[ { "id": "P14681-1.13.13", "start_pos": 13, "end_pos": 13, "uniprot_canonical_ac": "P14681-1", "length": 368, "uniprot_id": "KSS1_YEAST", "protein_name": "Mitogen-activated protein kinase KSS1", "refseq_ac": "NP_011554", "refseq_name": "mitogen-activated serine/threonine-protein kinase KSS1", "gene_name": "KSS1", "gene_names_uniprotkb": "KSS1", "gene_names_refseq": "KSS1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P14681", "url": "https://www.uniprot.org/uniprotkb/P14681" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P14681", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P14681" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000003272", "url": "https://www.yeastgenome.org/locus/S000003272", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P14681", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P14681", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "MARTITFDIPSQ", "down_seq": "KLVDLIGEGAYGTVCSAIHK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003272", "url": "https://www.yeastgenome.org/locus/S000003272" }, { "database": "iPTMnet", "id": "P14681", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P14681" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Tyr13" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "26", "end_pos": "26" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P14681-1.11.11", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P14681-1.26.26", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P14681-1.183.183", "start_pos": 183, "end_pos": 183, "uniprot_canonical_ac": "P14681-1", "length": 368, "uniprot_id": "KSS1_YEAST", "protein_name": "Mitogen-activated protein kinase KSS1", "refseq_ac": "NP_011554", "refseq_name": "mitogen-activated serine/threonine-protein kinase KSS1", "gene_name": "KSS1", "gene_names_uniprotkb": "KSS1", "gene_names_refseq": "KSS1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P14681", "url": "https://www.uniprot.org/uniprotkb/P14681" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "Journal of proteome research", "date": "2007-03", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "UniProtKB", "id": "P14681", "url": "https://www.uniprot.org/uniprotkb/P14681" }, { "database": "iPTMnet", "id": "P14681", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P14681" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "Specificity of MAP kinase signaling in yeast differentiation involves transient versus sustained MAPK activation.", "journal": "Molecular cell", "date": "2001-09", "authors": "Sabbagh W, Flatauer L J, Bardwell A J, Bardwell L", "evidence": [ { "database": "UniProtKB", "id": "P14681", "url": "https://www.uniprot.org/uniprotkb/P14681" }, { "database": "iPTMnet", "id": "P14681", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P14681" } ], "reference": [ { "type": "PubMed", "id": "11583629", "url": "https://glygen.org/publication/PubMed/11583629" } ] }, { "title": "A conserved protein interaction network involving the yeast MAP kinases Fus3 and Kss1.", "journal": "The Journal of cell biology", "date": "2004-01-19", "authors": "Kusari Anasua B, Molina Douglas M, Sabbagh Walid, Lau Chang S, Bardwell Lee", "evidence": [ { "database": "iPTMnet", "id": "P14681", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P14681" } ], "reference": [ { "type": "PubMed", "id": "14734536", "url": "https://glygen.org/publication/PubMed/14734536" } ] }, { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P14681", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P14681" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "Combined computational and experimental analysis reveals mitogen-activated protein kinase-mediated feedback phosphorylation as a mechanism for signaling specificity.", "journal": "Molecular biology of the cell", "date": "2012-10", "authors": "Hao Nan, Yildirim Necmettin, Nagiec Michal J, Parnell Stephen C, Errede Beverly, Dohlman Henrik G, Elston Timothy C", "evidence": [ { "database": "iPTMnet", "id": "P14681", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P14681" } ], "reference": [ { "type": "PubMed", "id": "22875986", "url": "https://glygen.org/publication/PubMed/22875986" } ] }, { "title": "Phosphorylation and localization of Kss1, a MAP kinase of the Saccharomyces cerevisiae pheromone response pathway.", "journal": "Molecular biology of the cell", "date": "1995-07", "authors": "Ma D, Cook J G, Thorner J", "evidence": [ { "database": "iPTMnet", "id": "P14681", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P14681" } ], "reference": [ { "type": "PubMed", "id": "7579701", "url": "https://glygen.org/publication/PubMed/7579701" } ] }, { "title": "Signal transduction in Saccharomyces cerevisiae requires tyrosine and threonine phosphorylation of FUS3 and KSS1.", "journal": "Genes & development", "date": "1992-07", "authors": "Gartner A, Nasmyth K, Ammerer G", "evidence": [ { "database": "UniProtKB", "id": "P14681", "url": "https://www.uniprot.org/uniprotkb/P14681" }, { "database": "iPTMnet", "id": "P14681", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P14681" } ], "reference": [ { "type": "PubMed", "id": "1628831", "url": "https://glygen.org/publication/PubMed/1628831" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P14681", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P14681" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P14681", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P14681" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P14681", "url": "https://www.uniprot.org/uniprotkb/P14681", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P14681", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P14681", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "11583629", "url": "https://glygen.org/publication/PubMed/11583629", "database": "PubMed", "categories": [ "Other" ] }, { "id": "14734536", "url": "https://glygen.org/publication/PubMed/14734536", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22875986", "url": "https://glygen.org/publication/PubMed/22875986", "database": "PubMed", "categories": [ "Other" ] }, { "id": "7579701", "url": "https://glygen.org/publication/PubMed/7579701", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000003272", "url": "https://www.yeastgenome.org/locus/S000003272", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "1628831", "url": "https://glygen.org/publication/PubMed/1628831", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "GLARCLASSSDSRETLVGFM", "down_seq": "EYVATRWYRAPEIMLTFQEY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P14681", "url": "https://www.uniprot.org/uniprotkb/P14681" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P14681", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P14681" }, { "database": "PubMed", "id": "11583629", "url": "https://glygen.org/publication/PubMed/11583629" }, { "database": "PubMed", "id": "14734536", "url": "https://glygen.org/publication/PubMed/14734536" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "22875986", "url": "https://glygen.org/publication/PubMed/22875986" }, { "database": "PubMed", "id": "7579701", "url": "https://glygen.org/publication/PubMed/7579701" }, { "database": "SGD", "id": "S000003272", "url": "https://www.yeastgenome.org/locus/S000003272" }, { "database": "PubMed", "id": "1628831", "url": "https://glygen.org/publication/PubMed/1628831" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr183" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "26", "end_pos": "26" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P14681-1.185.185", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 9 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P14681-1.185.185", "start_pos": 185, "end_pos": 185, "uniprot_canonical_ac": "P14681-1", "length": 368, "uniprot_id": "KSS1_YEAST", "protein_name": "Mitogen-activated protein kinase KSS1", "refseq_ac": "NP_011554", "refseq_name": "mitogen-activated serine/threonine-protein kinase KSS1", "gene_name": "KSS1", "gene_names_uniprotkb": "KSS1", "gene_names_refseq": "KSS1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P14681", "url": "https://www.uniprot.org/uniprotkb/P14681" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "Journal of proteome research", "date": "2007-03", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "UniProtKB", "id": "P14681", "url": "https://www.uniprot.org/uniprotkb/P14681" }, { "database": "iPTMnet", "id": "P14681", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P14681" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "A conserved protein interaction network involving the yeast MAP kinases Fus3 and Kss1.", "journal": "The Journal of cell biology", "date": "2004-01-19", "authors": "Kusari Anasua B, Molina Douglas M, Sabbagh Walid, Lau Chang S, Bardwell Lee", "evidence": [ { "database": "iPTMnet", "id": "P14681", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P14681" } ], "reference": [ { "type": "PubMed", "id": "14734536", "url": "https://glygen.org/publication/PubMed/14734536" } ] }, { "title": "Combined computational and experimental analysis reveals mitogen-activated protein kinase-mediated feedback phosphorylation as a mechanism for signaling specificity.", "journal": "Molecular biology of the cell", "date": "2012-10", "authors": "Hao Nan, Yildirim Necmettin, Nagiec Michal J, Parnell Stephen C, Errede Beverly, Dohlman Henrik G, Elston Timothy C", "evidence": [ { "database": "iPTMnet", "id": "P14681", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P14681" } ], "reference": [ { "type": "PubMed", "id": "22875986", "url": "https://glygen.org/publication/PubMed/22875986" } ] }, { "title": "Phosphorylation and localization of Kss1, a MAP kinase of the Saccharomyces cerevisiae pheromone response pathway.", "journal": "Molecular biology of the cell", "date": "1995-07", "authors": "Ma D, Cook J G, Thorner J", "evidence": [ { "database": "iPTMnet", "id": "P14681", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P14681" } ], "reference": [ { "type": "PubMed", "id": "7579701", "url": "https://glygen.org/publication/PubMed/7579701" } ] }, { "title": "Signal transduction in Saccharomyces cerevisiae requires tyrosine and threonine phosphorylation of FUS3 and KSS1.", "journal": "Genes & development", "date": "1992-07", "authors": "Gartner A, Nasmyth K, Ammerer G", "evidence": [ { "database": "UniProtKB", "id": "P14681", "url": "https://www.uniprot.org/uniprotkb/P14681" }, { "database": "iPTMnet", "id": "P14681", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P14681" } ], "reference": [ { "type": "PubMed", "id": "1628831", "url": "https://glygen.org/publication/PubMed/1628831" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P14681", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P14681" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P14681", "url": "https://www.uniprot.org/uniprotkb/P14681", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P14681", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P14681", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "14734536", "url": "https://glygen.org/publication/PubMed/14734536", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22875986", "url": "https://glygen.org/publication/PubMed/22875986", "database": "PubMed", "categories": [ "Other" ] }, { "id": "7579701", "url": "https://glygen.org/publication/PubMed/7579701", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000003272", "url": "https://www.yeastgenome.org/locus/S000003272", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "1628831", "url": "https://glygen.org/publication/PubMed/1628831", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "ARCLASSSDSRETLVGFMTE", "down_seq": "VATRWYRAPEIMLTFQEYTT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "P14681", "url": "https://www.uniprot.org/uniprotkb/P14681" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P14681", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P14681" }, { "database": "PubMed", "id": "14734536", "url": "https://glygen.org/publication/PubMed/14734536" }, { "database": "PubMed", "id": "22875986", "url": "https://glygen.org/publication/PubMed/22875986" }, { "database": "PubMed", "id": "7579701", "url": "https://glygen.org/publication/PubMed/7579701" }, { "database": "SGD", "id": "S000003272", "url": "https://www.yeastgenome.org/locus/S000003272" }, { "database": "PubMed", "id": "1628831", "url": "https://glygen.org/publication/PubMed/1628831" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Tyr185" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "26", "end_pos": "26" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P14681-1.183.183", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P14681-1.26.26", "start_pos": 26, "end_pos": 26, "uniprot_canonical_ac": "P14681-1", "length": 368, "uniprot_id": "KSS1_YEAST", "protein_name": "Mitogen-activated protein kinase KSS1", "refseq_ac": "NP_011554", "refseq_name": "mitogen-activated serine/threonine-protein kinase KSS1", "gene_name": "KSS1", "gene_names_uniprotkb": "KSS1", "gene_names_refseq": "KSS1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P14681", "url": "https://www.uniprot.org/uniprotkb/P14681" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P14681", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P14681" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] } ], "crossref": [ { "id": "P14681", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P14681", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000003272", "url": "https://www.yeastgenome.org/locus/S000003272", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "TFDIPSQYKLVDLIGEGAYG", "down_seq": "VCSAIHKPSGIKVAIKKIQP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P14681", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P14681" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000003272", "url": "https://www.yeastgenome.org/locus/S000003272" } ], "site_lbl": "Thr26" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "26", "end_pos": "26" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P14681-1.11.11", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P14681-1.13.13", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P14741-1.291.291", "start_pos": 291, "end_pos": 291, "uniprot_canonical_ac": "P14741-1", "length": 305, "uniprot_id": "EI2BA_YEAST", "protein_name": "Translation initiation factor eIF2B subunit alpha", "refseq_ac": "NP_012951", "refseq_name": "translation initiation factor eIF2B subunit alpha", "gene_name": "GCN3", "gene_names_uniprotkb": "GCN3; AAS2; TIF221", "gene_names_refseq": "AAS2; GCN3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P14741", "url": "https://www.uniprot.org/uniprotkb/P14741" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P14741", "url": "https://www.uniprot.org/uniprotkb/P14741" }, { "database": "iPTMnet", "id": "P14741", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P14741" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ], "crossref": [ { "id": "P14741", "url": "https://www.uniprot.org/uniprotkb/P14741", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P14741", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P14741", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000001734", "url": "https://www.yeastgenome.org/locus/S000001734", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "TIDYTAQEYITALITDLGVL", "down_seq": "PSAVSEELIKMWYD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P14741", "url": "https://www.uniprot.org/uniprotkb/P14741" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P14741", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P14741" }, { "database": "SGD", "id": "S000001734", "url": "https://www.yeastgenome.org/locus/S000001734" } ], "site_lbl": "Thr291" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "291", "end_pos": "291" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.453.453", "start_pos": 453, "end_pos": 453, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Interaction between the N-terminal and middle regions is essential for the in vivo function of HSP90 molecular chaperone.", "journal": "The Journal of biological chemistry", "date": "2002-09-20", "authors": "Matsumoto Shigeki, Tanaka Etsuko, Nemoto Takayuki K, Ono Toshio, Takagi Takashi, Imai Jun, Kimura Yoko, Yahara Ichiro, Kobayakawa Takeshi, Ayuse Takao, Oi Kumiko, Mizuno Akio", "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "reference": [ { "type": "PubMed", "id": "12121981", "url": "https://glygen.org/publication/PubMed/12121981" } ] } ], "crossref": [ { "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "12121981", "url": "https://glygen.org/publication/PubMed/12121981", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "AALAKLLRYNSTKSVDELTS", "down_seq": "TDYVTRMPEHQKNIYYITGE", "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "A", "comment": "Leads to growth defect at 37 degrees Celsius, probably by disrupting the intramolecular interaction of the N-termini with the middle domains; when associated with A-493.", "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" }, { "database": "PubMed", "id": "12121981", "url": "https://glygen.org/publication/PubMed/12121981" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P15108-1.446.446", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P15108-1.452.452", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P15108-1.469.469", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P15108-1.471.471", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.493.493", "start_pos": 493, "end_pos": 493, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Interaction between the N-terminal and middle regions is essential for the in vivo function of HSP90 molecular chaperone.", "journal": "The Journal of biological chemistry", "date": "2002-09-20", "authors": "Matsumoto Shigeki, Tanaka Etsuko, Nemoto Takayuki K, Ono Toshio, Takagi Takashi, Imai Jun, Kimura Yoko, Yahara Ichiro, Kobayakawa Takeshi, Ayuse Takao, Oi Kumiko, Mizuno Akio", "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "reference": [ { "type": "PubMed", "id": "12121981", "url": "https://glygen.org/publication/PubMed/12121981" } ] } ], "crossref": [ { "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "12121981", "url": "https://glygen.org/publication/PubMed/12121981", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "E", "start_aa": "E", "up_seq": "ESLKAVEKSPFLDALKAKNF", "down_seq": "VLFLTDPIDEYAFTQLKEFE", "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Leads to growth defect at 37 degrees Celsius, probably by disrupting the intramolecular interaction of the N-termini with the middle domains; when associated with A-453.", "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" }, { "database": "PubMed", "id": "12121981", "url": "https://glygen.org/publication/PubMed/12121981" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P15108-1.474.474", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P15108-1.481.481", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.22.22", "start_pos": 22, "end_pos": 22, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Casein kinase 2 phosphorylation of Hsp90 threonine 22 modulates chaperone function and drug sensitivity.", "journal": "Oncotarget", "date": "2011-05", "authors": "Mollapour Mehdi, Tsutsumi Shinji, Kim Yeong Sang, Trepel Jane, Neckers Len", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "21576760", "url": "https://glygen.org/publication/PubMed/21576760" } ] } ], "crossref": [ { "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "21576760", "url": "https://glygen.org/publication/PubMed/21576760", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "AGETFEFQAEITQLMSLIIN", "down_seq": "VYSNKEIFLRELISNASDAL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798" }, { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" }, { "database": "PubMed", "id": "21576760", "url": "https://glygen.org/publication/PubMed/21576760" } ], "site_lbl": "Thr22" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P15108-1.24.24", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P15108-1.36.36", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.24.24", "start_pos": 24, "end_pos": 24, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Swe1Wee1-dependent tyrosine phosphorylation of Hsp90 regulates distinct facets of chaperone function.", "journal": "Molecular cell", "date": "2010-02-12", "authors": "Mollapour Mehdi, Tsutsumi Shinji, Donnelly Alison C, Beebe Kristin, Tokita Mari J, Lee Min-Jung, Lee Sunmin, Morra Giulia, Bourboulia Dimitra, Scroggins Bradley T, Colombo Giorgio, Blagg Brian S, Panaretou Barry, Stetler-Stevenson William G, Trepel Jane B, Piper Peter W, Prodromou Chrisostomos, Pearl Laurence H, Neckers Len", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "20159553", "url": "https://glygen.org/publication/PubMed/20159553" } ] } ], "crossref": [ { "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "20159553", "url": "https://glygen.org/publication/PubMed/20159553", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "ETFEFQAEITQLMSLIINTV", "down_seq": "SNKEIFLRELISNASDALDK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798" }, { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" }, { "database": "PubMed", "id": "20159553", "url": "https://glygen.org/publication/PubMed/20159553" } ], "site_lbl": "Tyr24" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P15108-1.22.22", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P15108-1.36.36", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.278.278", "start_pos": 278, "end_pos": 278, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" }, { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EEVQELEELNKTKPLWTRNP", "down_seq": "DITQEEYNAFYKSISNDWED", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser278" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "P15108-1.281.281", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P15108-1.291.291", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P15108-1.293.293", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.281.281", "start_pos": 281, "end_pos": 281, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" }, { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ], "crossref": [ { "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "QELEELNKTKPLWTRNPSDI", "down_seq": "QEEYNAFYKSISNDWEDPLY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798" } ], "site_lbl": "Thr281" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P15108-1.278.278", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P15108-1.291.291", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P15108-1.293.293", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.291.291", "start_pos": 291, "end_pos": 291, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] }, { "title": "Glucose intake hampers PKA-regulated HSP90 chaperone activity.", "journal": "eLife", "date": "2018-12-05", "authors": "Chen Yu-Chen, Jiang Pei-Heng, Chen Hsuan-Ming, Chen Chang-Han, Wang Yi-Ting, Chen Yu-Ju, Yu Chia-Jung, Teng Shu-Chun", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PLWTRNPSDITQEEYNAFYK", "down_seq": "ISNDWEDPLYVKHFSVEGQL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser291" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P15108-1.278.278", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P15108-1.281.281", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P15108-1.293.293", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.293.293", "start_pos": 293, "end_pos": 293, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" }, { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "Glucose intake hampers PKA-regulated HSP90 chaperone activity.", "journal": "eLife", "date": "2018-12-05", "authors": "Chen Yu-Chen, Jiang Pei-Heng, Chen Hsuan-Ming, Chen Chang-Han, Wang Yi-Ting, Chen Yu-Ju, Yu Chia-Jung, Teng Shu-Chun", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "WTRNPSDITQEEYNAFYKSI", "down_seq": "NDWEDPLYVKHFSVEGQLEF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser293" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P15108-1.278.278", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P15108-1.281.281", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P15108-1.291.291", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.330.330", "start_pos": 330, "end_pos": 330, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-06-19", "authors": "Smolka Marcus B, Albuquerque Claudio P, Chen Sheng-hong, Zhou Huilin", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" }, { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Glucose intake hampers PKA-regulated HSP90 chaperone activity.", "journal": "eLife", "date": "2018-12-05", "authors": "Chen Yu-Chen, Jiang Pei-Heng, Chen Hsuan-Ming, Chen Chang-Han, Wang Yi-Ting, Chen Yu-Ju, Yu Chia-Jung, Teng Shu-Chun", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QLEFRAILFIPKRAPFDLFE", "down_seq": "KKKKNNIKLYVRRVFITDEA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser330" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.367.367", "start_pos": 367, "end_pos": 367, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TDEAEDLIPEWLSFVKGVVD", "down_seq": "EDLPLNLSREMLQQNKIMKV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser367" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "upstream", "id": "P15108-1.375.375", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.36.36", "start_pos": 36, "end_pos": 36, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" }, { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MSLIINTVYSNKEIFLRELI", "down_seq": "NASDALDKIRYQALSDPKQL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser36" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "P15108-1.22.22", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P15108-1.24.24", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P15108-1.47.47", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P15108-1.51.51", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.375.375", "start_pos": 375, "end_pos": 375, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" }, { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PEWLSFVKGVVDSEDLPLNL", "down_seq": "REMLQQNKIMKVIRKNIVKK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser375" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "P15108-1.367.367", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.415.415", "start_pos": 415, "end_pos": 415, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KLIEAFNEIAEDSEQFDKFY", "down_seq": "AFAKNIKLGVHEDTQNRAAL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798" }, { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser415" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "upstream", "id": "P15108-1.429.429", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.429.429", "start_pos": 429, "end_pos": 429, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ], "crossref": [ { "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "QFDKFYSAFAKNIKLGVHED", "down_seq": "QNRAALAKLLRYNSTKSVDE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798" }, { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ], "site_lbl": "Thr429" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "P15108-1.415.415", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P15108-1.446.446", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.446.446", "start_pos": 446, "end_pos": 446, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" }, { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "HEDTQNRAALAKLLRYNSTK", "down_seq": "VDELTSLTDYVTRMPEHQKN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser446" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P15108-1.429.429", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P15108-1.452.452", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P15108-1.453.453", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.452.452", "start_pos": 452, "end_pos": 452, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" }, { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Glucose intake hampers PKA-regulated HSP90 chaperone activity.", "journal": "eLife", "date": "2018-12-05", "authors": "Chen Yu-Chen, Jiang Pei-Heng, Chen Hsuan-Ming, Chen Chang-Han, Wang Yi-Ting, Chen Yu-Ju, Yu Chia-Jung, Teng Shu-Chun", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RAALAKLLRYNSTKSVDELT", "down_seq": "LTDYVTRMPEHQKNIYYITG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser452" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "P15108-1.446.446", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P15108-1.453.453", "categories": [ "mutagenesis_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P15108-1.469.469", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P15108-1.471.471", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.469.469", "start_pos": 469, "end_pos": 469, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "ELTSLTDYVTRMPEHQKNIY", "down_seq": "ITGESLKAVEKSPFLDALKA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798" }, { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Tyr469" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P15108-1.452.452", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P15108-1.453.453", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P15108-1.471.471", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P15108-1.474.474", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P15108-1.481.481", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.471.471", "start_pos": 471, "end_pos": 471, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" }, { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ], "crossref": [ { "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "TSLTDYVTRMPEHQKNIYYI", "down_seq": "GESLKAVEKSPFLDALKAKN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798" } ], "site_lbl": "Thr471" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P15108-1.452.452", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "downstream", "id": "P15108-1.453.453", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P15108-1.469.469", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P15108-1.474.474", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P15108-1.481.481", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.474.474", "start_pos": 474, "end_pos": 474, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" }, { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TDYVTRMPEHQKNIYYITGE", "down_seq": "LKAVEKSPFLDALKAKNFEV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser474" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "P15108-1.469.469", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P15108-1.471.471", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P15108-1.481.481", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P15108-1.493.493", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.47.47", "start_pos": 47, "end_pos": 47, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "KEIFLRELISNASDALDKIR", "down_seq": "QALSDPKQLETEPDLFIRIT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Tyr47" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P15108-1.36.36", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P15108-1.51.51", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P15108-1.58.58", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P15108-1.67.67", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.481.481", "start_pos": 481, "end_pos": 481, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PEHQKNIYYITGESLKAVEK", "down_seq": "PFLDALKAKNFEVLFLTDPI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser481" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P15108-1.469.469", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P15108-1.471.471", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P15108-1.474.474", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P15108-1.493.493", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.516.516", "start_pos": 516, "end_pos": 516, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "FLTDPIDEYAFTQLKEFEGK", "down_seq": "LVDITKDFELEETDEEKAER", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798" }, { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr516" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "upstream", "id": "P15108-1.529.529", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.51.51", "start_pos": 51, "end_pos": 51, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" }, { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LRELISNASDALDKIRYQAL", "down_seq": "DPKQLETEPDLFIRITPKPE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798" }, { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser51" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P15108-1.36.36", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P15108-1.47.47", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P15108-1.58.58", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P15108-1.67.67", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.529.529", "start_pos": 529, "end_pos": 529, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" }, { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "LKEFEGKTLVDITKDFELEE", "down_seq": "DEEKAEREKEIKEYEPLTKA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr529" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P15108-1.516.516", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.576.576", "start_pos": 576, "end_pos": 576, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "DQVEKVVVSYKLLDAPAAIR", "down_seq": "GQFGWSANMERIMKAQALRD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr576" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "upstream", "id": "P15108-1.582.582", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.582.582", "start_pos": 582, "end_pos": 582, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VVSYKLLDAPAAIRTGQFGW", "down_seq": "ANMERIMKAQALRDSSMSSY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798" }, { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser582" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "P15108-1.576.576", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P15108-1.597.597", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P15108-1.598.598", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P15108-1.600.600", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P15108-1.601.601", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P15108-1.602.602", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.58.58", "start_pos": 58, "end_pos": 58, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "ASDALDKIRYQALSDPKQLE", "down_seq": "EPDLFIRITPKPEEKVLEIR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798" }, { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr58" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P15108-1.47.47", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P15108-1.51.51", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P15108-1.67.67", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.597.597", "start_pos": 597, "end_pos": 597, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-02-13", "authors": "Chi An, Huttenhower Curtis, Geer Lewis Y, Coon Joshua J, Syka John E P, Bai Dina L, Shabanowitz Jeffrey, Burke Daniel J, Troyanskaya Olga G, Hunt Donald F", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" }, { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GQFGWSANMERIMKAQALRD", "down_seq": "SMSSYMSSKKTFEISPKSPI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "SGD", "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser597" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P15108-1.582.582", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P15108-1.598.598", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P15108-1.600.600", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P15108-1.601.601", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P15108-1.602.602", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P15108-1.604.604", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P15108-1.608.608", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P15108-1.612.612", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P15108-1.615.615", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.598.598", "start_pos": 598, "end_pos": 598, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-02-13", "authors": "Chi An, Huttenhower Curtis, Geer Lewis Y, Coon Joshua J, Syka John E P, Bai Dina L, Shabanowitz Jeffrey, Burke Daniel J, Troyanskaya Olga G, Hunt Donald F", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" }, { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QFGWSANMERIMKAQALRDS", "down_seq": "MSSYMSSKKTFEISPKSPII", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser598" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P15108-1.582.582", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P15108-1.597.597", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P15108-1.600.600", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P15108-1.601.601", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P15108-1.602.602", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P15108-1.604.604", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P15108-1.608.608", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P15108-1.612.612", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P15108-1.615.615", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.600.600", "start_pos": 600, "end_pos": 600, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GWSANMERIMKAQALRDSSM", "down_seq": "SYMSSKKTFEISPKSPIIKE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798" }, { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser600" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P15108-1.582.582", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P15108-1.597.597", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P15108-1.598.598", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P15108-1.601.601", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P15108-1.602.602", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P15108-1.604.604", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P15108-1.608.608", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P15108-1.612.612", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P15108-1.615.615", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.601.601", "start_pos": 601, "end_pos": 601, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "WSANMERIMKAQALRDSSMS", "down_seq": "YMSSKKTFEISPKSPIIKEL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798" }, { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser601" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P15108-1.582.582", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P15108-1.597.597", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P15108-1.598.598", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P15108-1.600.600", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P15108-1.602.602", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P15108-1.604.604", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P15108-1.608.608", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P15108-1.612.612", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P15108-1.615.615", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.602.602", "start_pos": 602, "end_pos": 602, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" }, { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "SANMERIMKAQALRDSSMSS", "down_seq": "MSSKKTFEISPKSPIIKELK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Tyr602" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P15108-1.582.582", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P15108-1.597.597", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P15108-1.598.598", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P15108-1.600.600", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P15108-1.601.601", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P15108-1.604.604", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P15108-1.608.608", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P15108-1.612.612", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P15108-1.615.615", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.604.604", "start_pos": 604, "end_pos": 604, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NMERIMKAQALRDSSMSSYM", "down_seq": "SKKTFEISPKSPIIKELKKR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798" }, { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser604" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P15108-1.597.597", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P15108-1.598.598", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P15108-1.600.600", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P15108-1.601.601", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P15108-1.602.602", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P15108-1.608.608", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P15108-1.612.612", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P15108-1.615.615", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.608.608", "start_pos": 608, "end_pos": 608, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "IMKAQALRDSSMSSYMSSKK", "down_seq": "FEISPKSPIIKELKKRVDEG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798" }, { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr608" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P15108-1.597.597", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P15108-1.598.598", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P15108-1.600.600", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P15108-1.601.601", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P15108-1.602.602", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P15108-1.604.604", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P15108-1.612.612", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P15108-1.615.615", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.612.612", "start_pos": 612, "end_pos": 612, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QALRDSSMSSYMSSKKTFEI", "down_seq": "PKSPIIKELKKRVDEGGAQD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798" }, { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser612" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P15108-1.597.597", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P15108-1.598.598", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P15108-1.600.600", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P15108-1.601.601", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P15108-1.602.602", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P15108-1.604.604", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P15108-1.608.608", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P15108-1.615.615", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.615.615", "start_pos": 615, "end_pos": 615, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "Journal of proteome research", "date": "2007-03", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-06-19", "authors": "Smolka Marcus B, Albuquerque Claudio P, Chen Sheng-hong, Zhou Huilin", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" }, { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "crossref": [ { "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RDSSMSSYMSSKKTFEISPK", "down_seq": "PIIKELKKRVDEGGAQDKTV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Ser615" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P15108-1.597.597", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P15108-1.598.598", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P15108-1.600.600", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P15108-1.601.601", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P15108-1.602.602", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P15108-1.604.604", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P15108-1.608.608", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P15108-1.612.612", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.653.653", "start_pos": 653, "end_pos": 653, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" }, { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ], "crossref": [ { "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KTVKDLTNLLFETALLTSGF", "down_seq": "LEEPTSFASRINRLISLGLN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" }, { "database": "SGD", "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798" } ], "site_lbl": "Ser653" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.67.67", "start_pos": 67, "end_pos": 67, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "YQALSDPKQLETEPDLFIRI", "down_seq": "PKPEEKVLEIRDSGIGMTKA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798" }, { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr67" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P15108-1.47.47", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P15108-1.51.51", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P15108-1.58.58", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P15108-1.80.80", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15108-1.80.80", "start_pos": 80, "end_pos": 80, "uniprot_canonical_ac": "P15108-1", "length": 705, "uniprot_id": "HSC82_YEAST", "protein_name": "ATP-dependent molecular chaperone HSC82", "refseq_ac": "NP_013911", "refseq_name": "Hsp90 family chaperone HSC82", "gene_name": "HSC82", "gene_names_uniprotkb": "HSC82; YM8010.16", "gene_names_refseq": "HSC82; HSP90", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15108", "url": "https://www.uniprot.org/uniprotkb/P15108" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PDLFIRITPKPEEKVLEIRD", "down_seq": "GIGMTKAELINNLGTIAKSG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004798", "url": "https://www.yeastgenome.org/locus/S000004798" }, { "database": "iPTMnet", "id": "P15108", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15108" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser80" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "453", "end_pos": "453" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "429", "end_pos": "429" }, { "start_pos": "446", "end_pos": "446" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "516", "end_pos": "516" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "582", "end_pos": "582" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "597", "end_pos": "597" }, { "start_pos": "598", "end_pos": "598" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "602", "end_pos": "602" }, { "start_pos": "604", "end_pos": "604" }, { "start_pos": "608", "end_pos": "608" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P15108-1.67.67", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15705-1.213.213", "start_pos": 213, "end_pos": 213, "uniprot_canonical_ac": "P15705-1", "length": 589, "uniprot_id": "STI1_YEAST", "protein_name": "Heat shock protein STI1", "refseq_ac": "NP_014670", "refseq_name": "Hsp90 cochaperone STI1", "gene_name": "STI1", "gene_names_uniprotkb": "STI1; OR26.17", "gene_names_refseq": "STI1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15705", "url": "https://www.uniprot.org/uniprotkb/P15705" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P15705", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P15705" }, { "database": "O-GlcNAc Atlas", "id": "P15705", "url": "https://oglcnac.org/atlas/detail/P15705" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P15705", "url": "https://oglcnac.org/atlas/detail/P15705", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "GVDLNMDDINQSNSMPKEPE", "down_seq": "SKSTEQKKDAEPQSDSTTSK", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr213", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P15705", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P15705" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "217", "end_pos": "217" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "227", "end_pos": "227" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "482", "end_pos": "482" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "526", "end_pos": "526" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "P15705-1.214.214", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P15705-1.216.216", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P15705-1.217.217", "categories": [ "glycosylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P15705-1.227.227", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15705-1.214.214", "start_pos": 214, "end_pos": 214, "uniprot_canonical_ac": "P15705-1", "length": 589, "uniprot_id": "STI1_YEAST", "protein_name": "Heat shock protein STI1", "refseq_ac": "NP_014670", "refseq_name": "Hsp90 cochaperone STI1", "gene_name": "STI1", "gene_names_uniprotkb": "STI1; OR26.17", "gene_names_refseq": "STI1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15705", "url": "https://www.uniprot.org/uniprotkb/P15705" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P15705", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P15705" }, { "database": "O-GlcNAc Atlas", "id": "P15705", "url": "https://oglcnac.org/atlas/detail/P15705" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P15705", "url": "https://oglcnac.org/atlas/detail/P15705", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VDLNMDDINQSNSMPKEPET", "down_seq": "KSTEQKKDAEPQSDSTTSKE", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser214", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P15705", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P15705" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "217", "end_pos": "217" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "227", "end_pos": "227" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "482", "end_pos": "482" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "526", "end_pos": "526" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "P15705-1.213.213", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P15705-1.216.216", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P15705-1.217.217", "categories": [ "glycosylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P15705-1.227.227", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15705-1.216.216", "start_pos": 216, "end_pos": 216, "uniprot_canonical_ac": "P15705-1", "length": 589, "uniprot_id": "STI1_YEAST", "protein_name": "Heat shock protein STI1", "refseq_ac": "NP_014670", "refseq_name": "Hsp90 cochaperone STI1", "gene_name": "STI1", "gene_names_uniprotkb": "STI1; OR26.17", "gene_names_refseq": "STI1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15705", "url": "https://www.uniprot.org/uniprotkb/P15705" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P15705", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P15705" }, { "database": "O-GlcNAc Atlas", "id": "P15705", "url": "https://oglcnac.org/atlas/detail/P15705" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P15705", "url": "https://oglcnac.org/atlas/detail/P15705", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LNMDDINQSNSMPKEPETSK", "down_seq": "TEQKKDAEPQSDSTTSKENS", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser216", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P15705", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P15705" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "217", "end_pos": "217" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "227", "end_pos": "227" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "482", "end_pos": "482" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "526", "end_pos": "526" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P15705-1.213.213", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P15705-1.214.214", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P15705-1.217.217", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P15705-1.227.227", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15705-1.217.217", "start_pos": 217, "end_pos": 217, "uniprot_canonical_ac": "P15705-1", "length": 589, "uniprot_id": "STI1_YEAST", "protein_name": "Heat shock protein STI1", "refseq_ac": "NP_014670", "refseq_name": "Hsp90 cochaperone STI1", "gene_name": "STI1", "gene_names_uniprotkb": "STI1; OR26.17", "gene_names_refseq": "STI1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15705", "url": "https://www.uniprot.org/uniprotkb/P15705" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P15705", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P15705" }, { "database": "O-GlcNAc Atlas", "id": "P15705", "url": "https://oglcnac.org/atlas/detail/P15705" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P15705", "url": "https://oglcnac.org/atlas/detail/P15705", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "NMDDINQSNSMPKEPETSKS", "down_seq": "EQKKDAEPQSDSTTSKENSS", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr217", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P15705", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P15705" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "217", "end_pos": "217" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "227", "end_pos": "227" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "482", "end_pos": "482" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "526", "end_pos": "526" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P15705-1.213.213", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P15705-1.214.214", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P15705-1.216.216", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P15705-1.227.227", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15705-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "P15705-1", "length": 589, "uniprot_id": "STI1_YEAST", "protein_name": "Heat shock protein STI1", "refseq_ac": "NP_014670", "refseq_name": "Hsp90 cochaperone STI1", "gene_name": "STI1", "gene_names_uniprotkb": "STI1; OR26.17", "gene_names_refseq": "STI1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15705", "url": "https://www.uniprot.org/uniprotkb/P15705" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P15705", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P15705" }, { "database": "O-GlcNAc Atlas", "id": "P15705", "url": "https://oglcnac.org/atlas/detail/P15705" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P15705", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P15705", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P15705", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P15705" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "217", "end_pos": "217" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "227", "end_pos": "227" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "482", "end_pos": "482" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "526", "end_pos": "526" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P15705-1.2.2", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P15705-1.4.4", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15705-1.133.133", "start_pos": 133, "end_pos": 133, "uniprot_canonical_ac": "P15705-1", "length": 589, "uniprot_id": "STI1_YEAST", "protein_name": "Heat shock protein STI1", "refseq_ac": "NP_014670", "refseq_name": "Hsp90 cochaperone STI1", "gene_name": "STI1", "gene_names_uniprotkb": "STI1; OR26.17", "gene_names_refseq": "STI1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15705", "url": "https://www.uniprot.org/uniprotkb/P15705" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005553", "url": "https://www.yeastgenome.org/locus/S000005553", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "GLDQVHRTQQARQAQPDLGL", "down_seq": "QLFADPNLIENLKKNPKTSE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005553", "url": "https://www.yeastgenome.org/locus/S000005553" }, { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr133" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "217", "end_pos": "217" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "227", "end_pos": "227" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "482", "end_pos": "482" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "526", "end_pos": "526" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15705-1.227.227", "start_pos": 227, "end_pos": 227, "uniprot_canonical_ac": "P15705-1", "length": 589, "uniprot_id": "STI1_YEAST", "protein_name": "Heat shock protein STI1", "refseq_ac": "NP_014670", "refseq_name": "Hsp90 cochaperone STI1", "gene_name": "STI1", "gene_names_uniprotkb": "STI1; OR26.17", "gene_names_refseq": "STI1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15705", "url": "https://www.uniprot.org/uniprotkb/P15705" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P15705", "url": "https://www.uniprot.org/uniprotkb/P15705" }, { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-06-19", "authors": "Smolka Marcus B, Albuquerque Claudio P, Chen Sheng-hong, Zhou Huilin", "evidence": [ { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" } ], "reference": [ { "type": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] }, { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] }, { "title": "Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast.", "journal": "Science signaling", "date": "2010-12-21", "authors": "Bodenmiller Bernd, Wanka Stefanie, Kraft Claudine, Urban J\u00f6rg, Campbell David, Pedrioli Patrick G, Gerrits Bertran, Picotti Paola, Lam Henry, Vitek Olga, Brusniak Mi-Youn, Roschitzki Bernd, Zhang Chao, Shokat Kevan M, Schlapbach Ralph, Colman-Lerner Alejandro, Nolan Garry P, Nesvizhskii Alexey I, Peter Matthias, Loewith Robbie, von Mering Christian, Aebersold Ruedi", "evidence": [ { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" } ], "reference": [ { "type": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P15705", "url": "https://www.uniprot.org/uniprotkb/P15705", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005553", "url": "https://www.yeastgenome.org/locus/S000005553", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MPKEPETSKSTEQKKDAEPQ", "down_seq": "DSTTSKENSSKAPQKEESKE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P15705", "url": "https://www.uniprot.org/uniprotkb/P15705" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005553", "url": "https://www.yeastgenome.org/locus/S000005553" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser227" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "217", "end_pos": "217" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "227", "end_pos": "227" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "482", "end_pos": "482" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "526", "end_pos": "526" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "P15705-1.213.213", "categories": [ "glycosylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P15705-1.214.214", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P15705-1.216.216", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P15705-1.217.217", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 7 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15705-1.248.248", "start_pos": 248, "end_pos": 248, "uniprot_canonical_ac": "P15705-1", "length": 589, "uniprot_id": "STI1_YEAST", "protein_name": "Heat shock protein STI1", "refseq_ac": "NP_014670", "refseq_name": "Hsp90 cochaperone STI1", "gene_name": "STI1", "gene_names_uniprotkb": "STI1; OR26.17", "gene_names_refseq": "STI1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15705", "url": "https://www.uniprot.org/uniprotkb/P15705" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ], "crossref": [ { "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DSTTSKENSSKAPQKEESKE", "down_seq": "EPMEVDEDDSKIEADKEKAE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ], "site_lbl": "Ser248" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "217", "end_pos": "217" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "227", "end_pos": "227" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "482", "end_pos": "482" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "526", "end_pos": "526" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "upstream", "id": "P15705-1.258.258", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15705-1.258.258", "start_pos": 258, "end_pos": 258, "uniprot_canonical_ac": "P15705-1", "length": 589, "uniprot_id": "STI1_YEAST", "protein_name": "Heat shock protein STI1", "refseq_ac": "NP_014670", "refseq_name": "Hsp90 cochaperone STI1", "gene_name": "STI1", "gene_names_uniprotkb": "STI1; OR26.17", "gene_names_refseq": "STI1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15705", "url": "https://www.uniprot.org/uniprotkb/P15705" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005553", "url": "https://www.yeastgenome.org/locus/S000005553", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KAPQKEESKESEPMEVDEDD", "down_seq": "KIEADKEKAEGNKFYKARQF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005553", "url": "https://www.yeastgenome.org/locus/S000005553" }, { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser258" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "217", "end_pos": "217" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "227", "end_pos": "227" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "482", "end_pos": "482" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "526", "end_pos": "526" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "P15705-1.248.248", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15705-1.296.296", "start_pos": 296, "end_pos": 296, "uniprot_canonical_ac": "P15705-1", "length": 589, "uniprot_id": "STI1_YEAST", "protein_name": "Heat shock protein STI1", "refseq_ac": "NP_014670", "refseq_name": "Hsp90 cochaperone STI1", "gene_name": "STI1", "gene_names_uniprotkb": "STI1; OR26.17", "gene_names_refseq": "STI1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15705", "url": "https://www.uniprot.org/uniprotkb/P15705" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005553", "url": "https://www.yeastgenome.org/locus/S000005553", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "RQFDEAIEHYNKAWELHKDI", "down_seq": "YLNNRAAAEYEKGEYETAIS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005553", "url": "https://www.yeastgenome.org/locus/S000005553" }, { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr296" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "217", "end_pos": "217" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "227", "end_pos": "227" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "482", "end_pos": "482" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "526", "end_pos": "526" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "upstream", "id": "P15705-1.316.316", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15705-1.2.2", "start_pos": 2, "end_pos": 2, "uniprot_canonical_ac": "P15705-1", "length": 589, "uniprot_id": "STI1_YEAST", "protein_name": "Heat shock protein STI1", "refseq_ac": "NP_014670", "refseq_name": "Hsp90 cochaperone STI1", "gene_name": "STI1", "gene_names_uniprotkb": "STI1; OR26.17", "gene_names_refseq": "STI1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15705", "url": "https://www.uniprot.org/uniprotkb/P15705" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P15705", "url": "https://www.uniprot.org/uniprotkb/P15705" }, { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005553", "url": "https://www.yeastgenome.org/locus/S000005553", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "M", "down_seq": "LTADEYKQQGNAAFTAKDYD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005553", "url": "https://www.yeastgenome.org/locus/S000005553" }, { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser2" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "217", "end_pos": "217" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "227", "end_pos": "227" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "482", "end_pos": "482" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "526", "end_pos": "526" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P15705-1.0.0", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P15705-1.4.4", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15705-1.316.316", "start_pos": 316, "end_pos": 316, "uniprot_canonical_ac": "P15705-1", "length": 589, "uniprot_id": "STI1_YEAST", "protein_name": "Heat shock protein STI1", "refseq_ac": "NP_014670", "refseq_name": "Hsp90 cochaperone STI1", "gene_name": "STI1", "gene_names_uniprotkb": "STI1; OR26.17", "gene_names_refseq": "STI1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15705", "url": "https://www.uniprot.org/uniprotkb/P15705" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005553", "url": "https://www.yeastgenome.org/locus/S000005553", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TYLNNRAAAEYEKGEYETAI", "down_seq": "TLNDAVEQGREMRADYKVIS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005553", "url": "https://www.yeastgenome.org/locus/S000005553" }, { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser316" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "217", "end_pos": "217" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "227", "end_pos": "227" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "482", "end_pos": "482" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "526", "end_pos": "526" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P15705-1.296.296", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15705-1.37.37", "start_pos": 37, "end_pos": 37, "uniprot_canonical_ac": "P15705-1", "length": 589, "uniprot_id": "STI1_YEAST", "protein_name": "Heat shock protein STI1", "refseq_ac": "NP_014670", "refseq_name": "Hsp90 cochaperone STI1", "gene_name": "STI1", "gene_names_uniprotkb": "STI1; OR26.17", "gene_names_refseq": "STI1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15705", "url": "https://www.uniprot.org/uniprotkb/P15705" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005553", "url": "https://www.yeastgenome.org/locus/S000005553", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "TAKDYDKAIELFTKAIEVSE", "down_seq": "PNHVLYSNRSACYTSLKKFS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005553", "url": "https://www.yeastgenome.org/locus/S000005553" }, { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr37" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "217", "end_pos": "217" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "227", "end_pos": "227" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "482", "end_pos": "482" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "526", "end_pos": "526" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "upstream", "id": "P15705-1.47.47", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P15705-1.52.52", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15705-1.410.410", "start_pos": 410, "end_pos": 410, "uniprot_canonical_ac": "P15705-1", "length": 589, "uniprot_id": "STI1_YEAST", "protein_name": "Heat shock protein STI1", "refseq_ac": "NP_014670", "refseq_name": "Hsp90 cochaperone STI1", "gene_name": "STI1", "gene_names_uniprotkb": "STI1; OR26.17", "gene_names_refseq": "STI1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15705", "url": "https://www.uniprot.org/uniprotkb/P15705" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000005553", "url": "https://www.yeastgenome.org/locus/S000005553", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "YVNPEKAEEARLEGKEYFTK", "down_seq": "DWPNAVKAYTEMIKRAPEDA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005553", "url": "https://www.yeastgenome.org/locus/S000005553" }, { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser410" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "217", "end_pos": "217" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "227", "end_pos": "227" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "482", "end_pos": "482" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "526", "end_pos": "526" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15705-1.47.47", "start_pos": 47, "end_pos": 47, "uniprot_canonical_ac": "P15705-1", "length": 589, "uniprot_id": "STI1_YEAST", "protein_name": "Heat shock protein STI1", "refseq_ac": "NP_014670", "refseq_name": "Hsp90 cochaperone STI1", "gene_name": "STI1", "gene_names_uniprotkb": "STI1; OR26.17", "gene_names_refseq": "STI1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15705", "url": "https://www.uniprot.org/uniprotkb/P15705" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000005553", "url": "https://www.yeastgenome.org/locus/S000005553", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LFTKAIEVSETPNHVLYSNR", "down_seq": "ACYTSLKKFSDALNDANECV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005553", "url": "https://www.yeastgenome.org/locus/S000005553" }, { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser47" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "217", "end_pos": "217" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "227", "end_pos": "227" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "482", "end_pos": "482" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "526", "end_pos": "526" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "P15705-1.37.37", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P15705-1.52.52", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15705-1.482.482", "start_pos": 482, "end_pos": 482, "uniprot_canonical_ac": "P15705-1", "length": 589, "uniprot_id": "STI1_YEAST", "protein_name": "Heat shock protein STI1", "refseq_ac": "NP_014670", "refseq_name": "Hsp90 cochaperone STI1", "gene_name": "STI1", "gene_names_uniprotkb": "STI1; OR26.17", "gene_names_refseq": "STI1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15705", "url": "https://www.uniprot.org/uniprotkb/P15705" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000005553", "url": "https://www.yeastgenome.org/locus/S000005553", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NFVRAYIRKATAQIAVKEYA", "down_seq": "ALETLDAARTKDAEVNNGSS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005553", "url": "https://www.yeastgenome.org/locus/S000005553" }, { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser482" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "217", "end_pos": "217" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "227", "end_pos": "227" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "482", "end_pos": "482" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "526", "end_pos": "526" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15705-1.4.4", "start_pos": 4, "end_pos": 4, "uniprot_canonical_ac": "P15705-1", "length": 589, "uniprot_id": "STI1_YEAST", "protein_name": "Heat shock protein STI1", "refseq_ac": "NP_014670", "refseq_name": "Hsp90 cochaperone STI1", "gene_name": "STI1", "gene_names_uniprotkb": "STI1; OR26.17", "gene_names_refseq": "STI1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15705", "url": "https://www.uniprot.org/uniprotkb/P15705" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005553", "url": "https://www.yeastgenome.org/locus/S000005553", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "MSL", "down_seq": "ADEYKQQGNAAFTAKDYDKA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005553", "url": "https://www.yeastgenome.org/locus/S000005553" }, { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr4" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "217", "end_pos": "217" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "227", "end_pos": "227" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "482", "end_pos": "482" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "526", "end_pos": "526" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P15705-1.0.0", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P15705-1.2.2", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15705-1.522.522", "start_pos": 522, "end_pos": 522, "uniprot_canonical_ac": "P15705-1", "length": 589, "uniprot_id": "STI1_YEAST", "protein_name": "Heat shock protein STI1", "refseq_ac": "NP_014670", "refseq_name": "Hsp90 cochaperone STI1", "gene_name": "STI1", "gene_names_uniprotkb": "STI1; OR26.17", "gene_names_refseq": "STI1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15705", "url": "https://www.uniprot.org/uniprotkb/P15705" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005553", "url": "https://www.yeastgenome.org/locus/S000005553", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SAREIDQLYYKASQQRFQPG", "down_seq": "SNETPEETYQRAMKDPEVAA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005553", "url": "https://www.yeastgenome.org/locus/S000005553" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr522" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "217", "end_pos": "217" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "227", "end_pos": "227" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "482", "end_pos": "482" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "526", "end_pos": "526" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "P15705-1.523.523", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P15705-1.526.526", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15705-1.523.523", "start_pos": 523, "end_pos": 523, "uniprot_canonical_ac": "P15705-1", "length": 589, "uniprot_id": "STI1_YEAST", "protein_name": "Heat shock protein STI1", "refseq_ac": "NP_014670", "refseq_name": "Hsp90 cochaperone STI1", "gene_name": "STI1", "gene_names_uniprotkb": "STI1; OR26.17", "gene_names_refseq": "STI1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15705", "url": "https://www.uniprot.org/uniprotkb/P15705" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P15705", "url": "https://www.uniprot.org/uniprotkb/P15705" }, { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005553", "url": "https://www.yeastgenome.org/locus/S000005553", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AREIDQLYYKASQQRFQPGT", "down_seq": "NETPEETYQRAMKDPEVAAI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005553", "url": "https://www.yeastgenome.org/locus/S000005553" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser523" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "217", "end_pos": "217" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "227", "end_pos": "227" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "482", "end_pos": "482" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "526", "end_pos": "526" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "P15705-1.522.522", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P15705-1.526.526", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15705-1.526.526", "start_pos": 526, "end_pos": 526, "uniprot_canonical_ac": "P15705-1", "length": 589, "uniprot_id": "STI1_YEAST", "protein_name": "Heat shock protein STI1", "refseq_ac": "NP_014670", "refseq_name": "Hsp90 cochaperone STI1", "gene_name": "STI1", "gene_names_uniprotkb": "STI1; OR26.17", "gene_names_refseq": "STI1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15705", "url": "https://www.uniprot.org/uniprotkb/P15705" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005553", "url": "https://www.yeastgenome.org/locus/S000005553", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "IDQLYYKASQQRFQPGTSNE", "down_seq": "PEETYQRAMKDPEVAAIMQD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005553", "url": "https://www.yeastgenome.org/locus/S000005553" }, { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr526" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "217", "end_pos": "217" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "227", "end_pos": "227" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "482", "end_pos": "482" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "526", "end_pos": "526" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P15705-1.522.522", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P15705-1.523.523", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15705-1.52.52", "start_pos": 52, "end_pos": 52, "uniprot_canonical_ac": "P15705-1", "length": 589, "uniprot_id": "STI1_YEAST", "protein_name": "Heat shock protein STI1", "refseq_ac": "NP_014670", "refseq_name": "Hsp90 cochaperone STI1", "gene_name": "STI1", "gene_names_uniprotkb": "STI1; OR26.17", "gene_names_refseq": "STI1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15705", "url": "https://www.uniprot.org/uniprotkb/P15705" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000005553", "url": "https://www.yeastgenome.org/locus/S000005553", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IEVSETPNHVLYSNRSACYT", "down_seq": "LKKFSDALNDANECVKINPS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005553", "url": "https://www.yeastgenome.org/locus/S000005553" }, { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser52" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "217", "end_pos": "217" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "227", "end_pos": "227" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "482", "end_pos": "482" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "526", "end_pos": "526" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P15705-1.37.37", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P15705-1.47.47", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P15705-1.72.72", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15705-1.72.72", "start_pos": 72, "end_pos": 72, "uniprot_canonical_ac": "P15705-1", "length": 589, "uniprot_id": "STI1_YEAST", "protein_name": "Heat shock protein STI1", "refseq_ac": "NP_014670", "refseq_name": "Hsp90 cochaperone STI1", "gene_name": "STI1", "gene_names_uniprotkb": "STI1; OR26.17", "gene_names_refseq": "STI1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15705", "url": "https://www.uniprot.org/uniprotkb/P15705" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005553", "url": "https://www.yeastgenome.org/locus/S000005553", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SLKKFSDALNDANECVKINP", "down_seq": "WSKGYNRLGAAHLGLGDLDE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005553", "url": "https://www.yeastgenome.org/locus/S000005553" }, { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser72" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "217", "end_pos": "217" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "227", "end_pos": "227" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "482", "end_pos": "482" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "526", "end_pos": "526" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P15705-1.52.52", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15705-1.95.95", "start_pos": 95, "end_pos": 95, "uniprot_canonical_ac": "P15705-1", "length": 589, "uniprot_id": "STI1_YEAST", "protein_name": "Heat shock protein STI1", "refseq_ac": "NP_014670", "refseq_name": "Hsp90 cochaperone STI1", "gene_name": "STI1", "gene_names_uniprotkb": "STI1; OR26.17", "gene_names_refseq": "STI1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15705", "url": "https://www.uniprot.org/uniprotkb/P15705" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005553", "url": "https://www.yeastgenome.org/locus/S000005553", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KGYNRLGAAHLGLGDLDEAE", "down_seq": "NYKKALELDASNKAAKEGLD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005553", "url": "https://www.yeastgenome.org/locus/S000005553" }, { "database": "iPTMnet", "id": "P15705", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15705" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser95" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "213", "end_pos": "213" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "217", "end_pos": "217" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "227", "end_pos": "227" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "37", "end_pos": "37" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "482", "end_pos": "482" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "526", "end_pos": "526" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "72", "end_pos": "72" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15873-1.126.128", "start_pos": 126, "end_pos": 128, "uniprot_canonical_ac": "P15873-1", "length": 258, "uniprot_id": "PCNA_YEAST", "protein_name": "DNA sliding clamp PCNA", "refseq_ac": "NP_009645", "refseq_name": "proliferating cell nuclear antigen", "gene_name": "POL30", "gene_names_uniprotkb": "POL30; YBR0811", "gene_names_refseq": "POL30", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15873", "url": "https://www.uniprot.org/uniprotkb/P15873" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Mutations in yeast proliferating cell nuclear antigen define distinct sites for interaction with DNA polymerase delta and DNA polymerase epsilon.", "journal": "Molecular and cellular biology", "date": "1997-11", "authors": "Eissenberg J C, Ayyagari R, Gomes X V, Burgers P M", "evidence": [ { "database": "UniProtKB", "id": "P15873", "url": "https://www.uniprot.org/uniprotkb/P15873" } ], "reference": [ { "type": "PubMed", "id": "9343398", "url": "https://glygen.org/publication/PubMed/9343398" } ] } ], "crossref": [ { "id": "P15873", "url": "https://www.uniprot.org/uniprotkb/P15873", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "9343398", "url": "https://glygen.org/publication/PubMed/9343398", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "LKI", "start_aa": "L", "up_seq": "TKKDRIAEYSLKLMDIDADF", "down_seq": "EELQYDSTLSLPSSEFSKIV", "mutagenesis": [ { "sequence_org": "LKI", "sequence_mut": "AKA", "comment": "Strongly affects PCNA processivity factor activity for DNA polymerase delta. Mutator; mutations occur at a higher frequency than normal. Dumbell-shaped buds. Sensitive to ultraviolet light, hydroxyurea and methyl methanesulfonate. Decreases cell population growth.", "evidence": [ { "database": "UniProtKB", "id": "P15873", "url": "https://www.uniprot.org/uniprotkb/P15873" }, { "database": "PubMed", "id": "9343398", "url": "https://glygen.org/publication/PubMed/9343398" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "126", "end_pos": "128" }, { "start_pos": "252", "end_pos": "253" }, { "start_pos": "253", "end_pos": "254" }, { "start_pos": "256", "end_pos": "257" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "220", "end_pos": "220" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15873-1.252.253", "start_pos": 252, "end_pos": 253, "uniprot_canonical_ac": "P15873-1", "length": 258, "uniprot_id": "PCNA_YEAST", "protein_name": "DNA sliding clamp PCNA", "refseq_ac": "NP_009645", "refseq_name": "proliferating cell nuclear antigen", "gene_name": "POL30", "gene_names_uniprotkb": "POL30; YBR0811", "gene_names_refseq": "POL30", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15873", "url": "https://www.uniprot.org/uniprotkb/P15873" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Mutations in yeast proliferating cell nuclear antigen define distinct sites for interaction with DNA polymerase delta and DNA polymerase epsilon.", "journal": "Molecular and cellular biology", "date": "1997-11", "authors": "Eissenberg J C, Ayyagari R, Gomes X V, Burgers P M", "evidence": [ { "database": "UniProtKB", "id": "P15873", "url": "https://www.uniprot.org/uniprotkb/P15873" } ], "reference": [ { "type": "PubMed", "id": "9343398", "url": "https://glygen.org/publication/PubMed/9343398" } ] } ], "crossref": [ { "id": "P15873", "url": "https://www.uniprot.org/uniprotkb/P15873", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "9343398", "url": "https://glygen.org/publication/PubMed/9343398", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "PK", "start_aa": "P", "up_seq": "EAPALFQFDLKSGFLQFFLA", "down_seq": "FNDEE", "mutagenesis": [ { "sequence_org": "PK", "sequence_mut": "AA", "comment": "Strongly affects PCNA processivity factor activity for DNA polymerase epsilon. Mutator; mutations occur at a higher frequency than normal due to defective mismatch repair. Abnormal RAD27 activity. Dumbell-shaped buds. Sensitive to ultraviolet light, hydroxyurea and methyl methanesulfonate. Decreases cell population growth.", "evidence": [ { "database": "UniProtKB", "id": "P15873", "url": "https://www.uniprot.org/uniprotkb/P15873" }, { "database": "PubMed", "id": "9343398", "url": "https://glygen.org/publication/PubMed/9343398" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "126", "end_pos": "128" }, { "start_pos": "252", "end_pos": "253" }, { "start_pos": "253", "end_pos": "254" }, { "start_pos": "256", "end_pos": "257" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "220", "end_pos": "220" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 0, "direction": "upstream", "id": "P15873-1.253.254", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P15873-1.256.257", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15873-1.253.254", "start_pos": 253, "end_pos": 254, "uniprot_canonical_ac": "P15873-1", "length": 258, "uniprot_id": "PCNA_YEAST", "protein_name": "DNA sliding clamp PCNA", "refseq_ac": "NP_009645", "refseq_name": "proliferating cell nuclear antigen", "gene_name": "POL30", "gene_names_uniprotkb": "POL30; YBR0811", "gene_names_refseq": "POL30", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15873", "url": "https://www.uniprot.org/uniprotkb/P15873" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Mutations in yeast proliferating cell nuclear antigen define distinct sites for interaction with DNA polymerase delta and DNA polymerase epsilon.", "journal": "Molecular and cellular biology", "date": "1997-11", "authors": "Eissenberg J C, Ayyagari R, Gomes X V, Burgers P M", "evidence": [ { "database": "UniProtKB", "id": "P15873", "url": "https://www.uniprot.org/uniprotkb/P15873" } ], "reference": [ { "type": "PubMed", "id": "9343398", "url": "https://glygen.org/publication/PubMed/9343398" } ] } ], "crossref": [ { "id": "P15873", "url": "https://www.uniprot.org/uniprotkb/P15873", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "9343398", "url": "https://glygen.org/publication/PubMed/9343398", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "KF", "start_aa": "K", "up_seq": "APALFQFDLKSGFLQFFLAP", "down_seq": "NDEE", "mutagenesis": [ { "sequence_org": "KF", "sequence_mut": "AA", "comment": "Dumbell-shaped buds. Sensitive to cold, ultraviolet light, hydroxyurea and methyl methanesulfonate.", "evidence": [ { "database": "UniProtKB", "id": "P15873", "url": "https://www.uniprot.org/uniprotkb/P15873" }, { "database": "PubMed", "id": "9343398", "url": "https://glygen.org/publication/PubMed/9343398" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "126", "end_pos": "128" }, { "start_pos": "252", "end_pos": "253" }, { "start_pos": "253", "end_pos": "254" }, { "start_pos": "256", "end_pos": "257" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "220", "end_pos": "220" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 0, "direction": "downstream", "id": "P15873-1.252.253", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P15873-1.256.257", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15873-1.256.257", "start_pos": 256, "end_pos": 257, "uniprot_canonical_ac": "P15873-1", "length": 258, "uniprot_id": "PCNA_YEAST", "protein_name": "DNA sliding clamp PCNA", "refseq_ac": "NP_009645", "refseq_name": "proliferating cell nuclear antigen", "gene_name": "POL30", "gene_names_uniprotkb": "POL30; YBR0811", "gene_names_refseq": "POL30", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15873", "url": "https://www.uniprot.org/uniprotkb/P15873" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Mutations in yeast proliferating cell nuclear antigen define distinct sites for interaction with DNA polymerase delta and DNA polymerase epsilon.", "journal": "Molecular and cellular biology", "date": "1997-11", "authors": "Eissenberg J C, Ayyagari R, Gomes X V, Burgers P M", "evidence": [ { "database": "UniProtKB", "id": "P15873", "url": "https://www.uniprot.org/uniprotkb/P15873" } ], "reference": [ { "type": "PubMed", "id": "9343398", "url": "https://glygen.org/publication/PubMed/9343398" } ] } ], "crossref": [ { "id": "P15873", "url": "https://www.uniprot.org/uniprotkb/P15873", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "9343398", "url": "https://glygen.org/publication/PubMed/9343398", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "DE", "start_aa": "D", "up_seq": "LFQFDLKSGFLQFFLAPKFN", "down_seq": "", "mutagenesis": [ { "sequence_org": "DE", "sequence_mut": "AA", "comment": "Sensitive to ultraviolet light.", "evidence": [ { "database": "UniProtKB", "id": "P15873", "url": "https://www.uniprot.org/uniprotkb/P15873" }, { "database": "PubMed", "id": "9343398", "url": "https://glygen.org/publication/PubMed/9343398" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "126", "end_pos": "128" }, { "start_pos": "252", "end_pos": "253" }, { "start_pos": "253", "end_pos": "254" }, { "start_pos": "256", "end_pos": "257" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "220", "end_pos": "220" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P15873-1.252.253", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P15873-1.253.254", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15873-1.10.10", "start_pos": 10, "end_pos": 10, "uniprot_canonical_ac": "P15873-1", "length": 258, "uniprot_id": "PCNA_YEAST", "protein_name": "DNA sliding clamp PCNA", "refseq_ac": "NP_009645", "refseq_name": "proliferating cell nuclear antigen", "gene_name": "POL30", "gene_names_uniprotkb": "POL30; YBR0811", "gene_names_refseq": "POL30", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15873", "url": "https://www.uniprot.org/uniprotkb/P15873" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P15873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15873" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P15873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15873" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000292", "url": "https://www.yeastgenome.org/locus/S000000292", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P15873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15873", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MLEAKFEEA", "down_seq": "LFKRIIDGFKDCVQLVNFQC", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000292", "url": "https://www.yeastgenome.org/locus/S000000292" }, { "database": "iPTMnet", "id": "P15873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15873" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser10" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "126", "end_pos": "128" }, { "start_pos": "252", "end_pos": "253" }, { "start_pos": "253", "end_pos": "254" }, { "start_pos": "256", "end_pos": "257" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "220", "end_pos": "220" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15873-1.163.163", "start_pos": 163, "end_pos": 163, "uniprot_canonical_ac": "P15873-1", "length": 258, "uniprot_id": "PCNA_YEAST", "protein_name": "DNA sliding clamp PCNA", "refseq_ac": "NP_009645", "refseq_name": "proliferating cell nuclear antigen", "gene_name": "POL30", "gene_names_uniprotkb": "POL30; YBR0811", "gene_names_refseq": "POL30", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15873", "url": "https://www.uniprot.org/uniprotkb/P15873" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "SUMO is a pervasive regulator of meiosis.", "journal": "eLife", "date": "2021-01-27", "authors": "Bhagwat Nikhil R, Owens Shannon N, Ito Masaru, Boinapalli Jay V, Poa Philip, Ditzel Alexander, Kopparapu Srujan, Mahalawat Meghan, Davies Owen Richard, Collins Sean R, Johnson Jeffrey R, Krogan Nevan J, Hunter Neil", "evidence": [ { "database": "iPTMnet", "id": "P15873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15873" } ], "reference": [ { "type": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ] } ], "crossref": [ { "id": "S000000292", "url": "https://www.yeastgenome.org/locus/S000000292", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P15873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15873", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "EFSKIVRDLSQLSDSINIMI", "down_seq": "KETIKFVADGDIGSGSVIIK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000292", "url": "https://www.yeastgenome.org/locus/S000000292" }, { "database": "iPTMnet", "id": "P15873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15873" }, { "database": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ], "site_lbl": "Thr163" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "126", "end_pos": "128" }, { "start_pos": "252", "end_pos": "253" }, { "start_pos": "253", "end_pos": "254" }, { "start_pos": "256", "end_pos": "257" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "220", "end_pos": "220" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "P15873-1.166.166", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15873-1.166.166", "start_pos": 166, "end_pos": 166, "uniprot_canonical_ac": "P15873-1", "length": 258, "uniprot_id": "PCNA_YEAST", "protein_name": "DNA sliding clamp PCNA", "refseq_ac": "NP_009645", "refseq_name": "proliferating cell nuclear antigen", "gene_name": "POL30", "gene_names_uniprotkb": "POL30; YBR0811", "gene_names_refseq": "POL30", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15873", "url": "https://www.uniprot.org/uniprotkb/P15873" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "SUMO is a pervasive regulator of meiosis.", "journal": "eLife", "date": "2021-01-27", "authors": "Bhagwat Nikhil R, Owens Shannon N, Ito Masaru, Boinapalli Jay V, Poa Philip, Ditzel Alexander, Kopparapu Srujan, Mahalawat Meghan, Davies Owen Richard, Collins Sean R, Johnson Jeffrey R, Krogan Nevan J, Hunter Neil", "evidence": [ { "database": "iPTMnet", "id": "P15873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15873" } ], "reference": [ { "type": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ] } ], "crossref": [ { "id": "S000000292", "url": "https://www.yeastgenome.org/locus/S000000292", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P15873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15873", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "KIVRDLSQLSDSINIMITKE", "down_seq": "IKFVADGDIGSGSVIIKPFV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000292", "url": "https://www.yeastgenome.org/locus/S000000292" }, { "database": "iPTMnet", "id": "P15873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15873" }, { "database": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ], "site_lbl": "Thr166" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "126", "end_pos": "128" }, { "start_pos": "252", "end_pos": "253" }, { "start_pos": "253", "end_pos": "254" }, { "start_pos": "256", "end_pos": "257" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "220", "end_pos": "220" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P15873-1.163.163", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P15873-1.220.220", "start_pos": 220, "end_pos": 220, "uniprot_canonical_ac": "P15873-1", "length": 258, "uniprot_id": "PCNA_YEAST", "protein_name": "DNA sliding clamp PCNA", "refseq_ac": "NP_009645", "refseq_name": "proliferating cell nuclear antigen", "gene_name": "POL30", "gene_names_uniprotkb": "POL30; YBR0811", "gene_names_refseq": "POL30", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P15873", "url": "https://www.uniprot.org/uniprotkb/P15873" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P15873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15873" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000292", "url": "https://www.yeastgenome.org/locus/S000000292", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P15873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15873", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DQPVDLTFGAKYLLDIIKGS", "down_seq": "LSDRVGIRLSSEAPALFQFD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000292", "url": "https://www.yeastgenome.org/locus/S000000292" }, { "database": "iPTMnet", "id": "P15873", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15873" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser220" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "126", "end_pos": "128" }, { "start_pos": "252", "end_pos": "253" }, { "start_pos": "253", "end_pos": "254" }, { "start_pos": "256", "end_pos": "257" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "220", "end_pos": "220" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P16370-1.9.9", "start_pos": 9, "end_pos": 9, "uniprot_canonical_ac": "P16370-1", "length": 318, "uniprot_id": "RPB3_YEAST", "protein_name": "DNA-directed RNA polymerase II subunit RPB3", "refseq_ac": "NP_012243", "refseq_name": "DNA-directed RNA polymerase II core subunit RPB3", "gene_name": "RPB3", "gene_names_uniprotkb": "RPB3", "gene_names_refseq": "RPB3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P16370", "url": "https://www.uniprot.org/uniprotkb/P16370" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "cis- and trans-Acting determinants of transcription termination by yeast RNA polymerase II.", "journal": "Molecular and cellular biology", "date": "2006-04", "authors": "Steinmetz Eric J, Ng Sarah B H, Cloute Joseph P, Brow David A", "evidence": [ { "database": "UniProtKB", "id": "P16370", "url": "https://www.uniprot.org/uniprotkb/P16370" } ], "reference": [ { "type": "PubMed", "id": "16537912", "url": "https://glygen.org/publication/PubMed/16537912" } ] } ], "crossref": [ { "id": "P16370", "url": "https://www.uniprot.org/uniprotkb/P16370", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "16537912", "url": "https://glygen.org/publication/PubMed/16537912", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "MSEEGPQV", "down_seq": "IREASKDNVDFILSNVDLAM", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "E", "comment": "Transcript termination readthrough.", "evidence": [ { "database": "UniProtKB", "id": "P16370", "url": "https://www.uniprot.org/uniprotkb/P16370" }, { "database": "PubMed", "id": "16537912", "url": "https://glygen.org/publication/PubMed/16537912" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "9", "end_pos": "9" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "250", "end_pos": "250" }, { "start_pos": "2", "end_pos": "2" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P16370-1.2.2", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P16370-1.250.250", "start_pos": 250, "end_pos": 250, "uniprot_canonical_ac": "P16370-1", "length": 318, "uniprot_id": "RPB3_YEAST", "protein_name": "DNA-directed RNA polymerase II subunit RPB3", "refseq_ac": "NP_012243", "refseq_name": "DNA-directed RNA polymerase II core subunit RPB3", "gene_name": "RPB3", "gene_names_uniprotkb": "RPB3", "gene_names_refseq": "RPB3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P16370", "url": "https://www.uniprot.org/uniprotkb/P16370" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P16370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16370" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000001283", "url": "https://www.yeastgenome.org/locus/S000001283", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P16370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16370", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "MNVESVGSIPVDQVVVRGID", "down_seq": "LQKKVASILLALTQMDQDKV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000001283", "url": "https://www.yeastgenome.org/locus/S000001283" }, { "database": "iPTMnet", "id": "P16370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16370" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr250" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "9", "end_pos": "9" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "250", "end_pos": "250" }, { "start_pos": "2", "end_pos": "2" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P16370-1.2.2", "start_pos": 2, "end_pos": 2, "uniprot_canonical_ac": "P16370-1", "length": 318, "uniprot_id": "RPB3_YEAST", "protein_name": "DNA-directed RNA polymerase II subunit RPB3", "refseq_ac": "NP_012243", "refseq_name": "DNA-directed RNA polymerase II core subunit RPB3", "gene_name": "RPB3", "gene_names_uniprotkb": "RPB3", "gene_names_refseq": "RPB3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P16370", "url": "https://www.uniprot.org/uniprotkb/P16370" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P16370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16370" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000001283", "url": "https://www.yeastgenome.org/locus/S000001283", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P16370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16370", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "M", "down_seq": "EEGPQVKIREASKDNVDFIL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000001283", "url": "https://www.yeastgenome.org/locus/S000001283" }, { "database": "iPTMnet", "id": "P16370", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16370" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser2" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "9", "end_pos": "9" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "250", "end_pos": "250" }, { "start_pos": "2", "end_pos": "2" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "upstream", "id": "P16370-1.9.9", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P16892-1.11.11", "start_pos": 11, "end_pos": 11, "uniprot_canonical_ac": "P16892-1", "length": 353, "uniprot_id": "FUS3_YEAST", "protein_name": "Mitogen-activated protein kinase FUS3", "refseq_ac": "NP_009537", "refseq_name": "mitogen-activated serine/threonine-protein kinase FUS3", "gene_name": "FUS3", "gene_names_uniprotkb": "FUS3; DAC2; YBL03.21; YBL0303", "gene_names_refseq": "DAC2; FUS3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P16892", "url": "https://www.uniprot.org/uniprotkb/P16892" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000112", "url": "https://www.yeastgenome.org/locus/S000000112", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MPKRIVYNIS", "down_seq": "DFQLKSLLGEGAYGVVCSAT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000112", "url": "https://www.yeastgenome.org/locus/S000000112" }, { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser11" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "262", "end_pos": "262" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "upstream", "id": "P16892-1.17.17", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P16892-1.173.173", "start_pos": 173, "end_pos": 173, "uniprot_canonical_ac": "P16892-1", "length": 353, "uniprot_id": "FUS3_YEAST", "protein_name": "Mitogen-activated protein kinase FUS3", "refseq_ac": "NP_009537", "refseq_name": "mitogen-activated serine/threonine-protein kinase FUS3", "gene_name": "FUS3", "gene_names_uniprotkb": "FUS3; DAC2; YBL03.21; YBL0303", "gene_names_refseq": "DAC2; FUS3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P16892", "url": "https://www.uniprot.org/uniprotkb/P16892" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000000112", "url": "https://www.yeastgenome.org/locus/S000000112", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "VCDFGLARIIDESAADNSEP", "down_seq": "GQQSGMTEYVATRWYRAPEV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000112", "url": "https://www.yeastgenome.org/locus/S000000112" }, { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr173" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "262", "end_pos": "262" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "P16892-1.177.177", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P16892-1.180.180", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P16892-1.182.182", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P16892-1.177.177", "start_pos": 177, "end_pos": 177, "uniprot_canonical_ac": "P16892-1", "length": 353, "uniprot_id": "FUS3_YEAST", "protein_name": "Mitogen-activated protein kinase FUS3", "refseq_ac": "NP_009537", "refseq_name": "mitogen-activated serine/threonine-protein kinase FUS3", "gene_name": "FUS3", "gene_names_uniprotkb": "FUS3; DAC2; YBL03.21; YBL0303", "gene_names_refseq": "DAC2; FUS3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P16892", "url": "https://www.uniprot.org/uniprotkb/P16892" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000112", "url": "https://www.yeastgenome.org/locus/S000000112", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GLARIIDESAADNSEPTGQQ", "down_seq": "GMTEYVATRWYRAPEVMLTS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000112", "url": "https://www.yeastgenome.org/locus/S000000112" }, { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser177" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "262", "end_pos": "262" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P16892-1.173.173", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P16892-1.180.180", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P16892-1.182.182", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P16892-1.197.197", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P16892-1.17.17", "start_pos": 17, "end_pos": 17, "uniprot_canonical_ac": "P16892-1", "length": 353, "uniprot_id": "FUS3_YEAST", "protein_name": "Mitogen-activated protein kinase FUS3", "refseq_ac": "NP_009537", "refseq_name": "mitogen-activated serine/threonine-protein kinase FUS3", "gene_name": "FUS3", "gene_names_uniprotkb": "FUS3; DAC2; YBL03.21; YBL0303", "gene_names_refseq": "DAC2; FUS3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P16892", "url": "https://www.uniprot.org/uniprotkb/P16892" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000112", "url": "https://www.yeastgenome.org/locus/S000000112", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MPKRIVYNISSDFQLK", "down_seq": "LLGEGAYGVVCSATHKPTGE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000112", "url": "https://www.yeastgenome.org/locus/S000000112" }, { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser17" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "262", "end_pos": "262" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "P16892-1.11.11", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P16892-1.180.180", "start_pos": 180, "end_pos": 180, "uniprot_canonical_ac": "P16892-1", "length": 353, "uniprot_id": "FUS3_YEAST", "protein_name": "Mitogen-activated protein kinase FUS3", "refseq_ac": "NP_009537", "refseq_name": "mitogen-activated serine/threonine-protein kinase FUS3", "gene_name": "FUS3", "gene_names_uniprotkb": "FUS3; DAC2; YBL03.21; YBL0303", "gene_names_refseq": "DAC2; FUS3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P16892", "url": "https://www.uniprot.org/uniprotkb/P16892" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Signal transduction in Saccharomyces cerevisiae requires tyrosine and threonine phosphorylation of FUS3 and KSS1.", "journal": "Genes & development", "date": "1992-07", "authors": "Gartner A, Nasmyth K, Ammerer G", "evidence": [ { "database": "UniProtKB", "id": "P16892", "url": "https://www.uniprot.org/uniprotkb/P16892" }, { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" } ], "reference": [ { "type": "PubMed", "id": "1628831", "url": "https://glygen.org/publication/PubMed/1628831" } ] }, { "title": "Specificity of MAP kinase signaling in yeast differentiation involves transient versus sustained MAPK activation.", "journal": "Molecular cell", "date": "2001-09", "authors": "Sabbagh W, Flatauer L J, Bardwell A J, Bardwell L", "evidence": [ { "database": "UniProtKB", "id": "P16892", "url": "https://www.uniprot.org/uniprotkb/P16892" }, { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" } ], "reference": [ { "type": "PubMed", "id": "11583629", "url": "https://glygen.org/publication/PubMed/11583629" } ] }, { "title": "A conserved protein interaction network involving the yeast MAP kinases Fus3 and Kss1.", "journal": "The Journal of cell biology", "date": "2004-01-19", "authors": "Kusari Anasua B, Molina Douglas M, Sabbagh Walid, Lau Chang S, Bardwell Lee", "evidence": [ { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" } ], "reference": [ { "type": "PubMed", "id": "14734536", "url": "https://glygen.org/publication/PubMed/14734536" } ] }, { "title": "Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.", "journal": "Molecular & cellular proteomics : MCP", "date": "2005-03", "authors": "Gruhler Albrecht, Olsen Jesper V, Mohammed Shabaz, Mortensen Peter, Faergeman Nils J, Mann Matthias, Jensen Ole N", "evidence": [ { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" } ], "reference": [ { "type": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" } ] }, { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "MSG5, a novel protein phosphatase promotes adaptation to pheromone response in S. cerevisiae.", "journal": "The EMBO journal", "date": "1994-01-01", "authors": "Doi K, Gartner A, Ammerer G, Errede B, Shinkawa H, Sugimoto K, Matsumoto K", "evidence": [ { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" } ], "reference": [ { "type": "PubMed", "id": "8306972", "url": "https://glygen.org/publication/PubMed/8306972" } ] }, { "title": "MAP kinase-related FUS3 from S. cerevisiae is activated by STE7 in vitro.", "journal": "Nature", "date": "1993-03-18", "authors": "Errede B, Gartner A, Zhou Z, Nasmyth K, Ammerer G", "evidence": [ { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" } ], "reference": [ { "type": "PubMed", "id": "8384702", "url": "https://glygen.org/publication/PubMed/8384702" } ] }, { "title": "Pheromone-induced signal transduction in Saccharomyces cerevisiae requires the sequential function of three protein kinases.", "journal": "Molecular and cellular biology", "date": "1993-04", "authors": "Zhou Z, Gartner A, Cade R, Ammerer G, Errede B", "evidence": [ { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" } ], "reference": [ { "type": "PubMed", "id": "8455599", "url": "https://glygen.org/publication/PubMed/8455599" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Mol. Cell. Proteomics", "date": "2008", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P16892", "url": "https://www.uniprot.org/uniprotkb/P16892" }, { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Quantitative profiling of dual phosphorylation of Fus3 MAP kinase in Saccharomyces cerevisiae.", "journal": "Molecules and cells", "date": "2008-07-31", "authors": "Hur Jae-Young, Kang Gum-Yong, Choi Min-Yeon, Jung Jin Woo, Kim Kwang-Pyo, Park Sang-Hyun", "evidence": [ { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" } ], "reference": [ { "type": "PubMed", "id": "18596411", "url": "https://glygen.org/publication/PubMed/18596411" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P16892", "url": "https://www.uniprot.org/uniprotkb/P16892", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "1628831", "url": "https://glygen.org/publication/PubMed/1628831", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "11583629", "url": "https://glygen.org/publication/PubMed/11583629", "database": "PubMed", "categories": [ "Other" ] }, { "id": "14734536", "url": "https://glygen.org/publication/PubMed/14734536", "database": "PubMed", "categories": [ "Other" ] }, { "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "8306972", "url": "https://glygen.org/publication/PubMed/8306972", "database": "PubMed", "categories": [ "Other" ] }, { "id": "8384702", "url": "https://glygen.org/publication/PubMed/8384702", "database": "PubMed", "categories": [ "Other" ] }, { "id": "8455599", "url": "https://glygen.org/publication/PubMed/8455599", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000112", "url": "https://www.yeastgenome.org/locus/S000000112", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18596411", "url": "https://glygen.org/publication/PubMed/18596411", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "RIIDESAADNSEPTGQQSGM", "down_seq": "EYVATRWYRAPEVMLTSAKY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P16892", "url": "https://www.uniprot.org/uniprotkb/P16892" }, { "database": "PubMed", "id": "1628831", "url": "https://glygen.org/publication/PubMed/1628831" }, { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" }, { "database": "PubMed", "id": "11583629", "url": "https://glygen.org/publication/PubMed/11583629" }, { "database": "PubMed", "id": "14734536", "url": "https://glygen.org/publication/PubMed/14734536" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "8306972", "url": "https://glygen.org/publication/PubMed/8306972" }, { "database": "PubMed", "id": "8384702", "url": "https://glygen.org/publication/PubMed/8384702" }, { "database": "PubMed", "id": "8455599", "url": "https://glygen.org/publication/PubMed/8455599" }, { "database": "SGD", "id": "S000000112", "url": "https://www.yeastgenome.org/locus/S000000112" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "18596411", "url": "https://glygen.org/publication/PubMed/18596411" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr180" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "262", "end_pos": "262" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P16892-1.173.173", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P16892-1.177.177", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P16892-1.182.182", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P16892-1.197.197", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 12 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P16892-1.182.182", "start_pos": 182, "end_pos": 182, "uniprot_canonical_ac": "P16892-1", "length": 353, "uniprot_id": "FUS3_YEAST", "protein_name": "Mitogen-activated protein kinase FUS3", "refseq_ac": "NP_009537", "refseq_name": "mitogen-activated serine/threonine-protein kinase FUS3", "gene_name": "FUS3", "gene_names_uniprotkb": "FUS3; DAC2; YBL03.21; YBL0303", "gene_names_refseq": "DAC2; FUS3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P16892", "url": "https://www.uniprot.org/uniprotkb/P16892" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Signal transduction in Saccharomyces cerevisiae requires tyrosine and threonine phosphorylation of FUS3 and KSS1.", "journal": "Genes & development", "date": "1992-07", "authors": "Gartner A, Nasmyth K, Ammerer G", "evidence": [ { "database": "UniProtKB", "id": "P16892", "url": "https://www.uniprot.org/uniprotkb/P16892" }, { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" } ], "reference": [ { "type": "PubMed", "id": "1628831", "url": "https://glygen.org/publication/PubMed/1628831" } ] }, { "title": "Specificity of MAP kinase signaling in yeast differentiation involves transient versus sustained MAPK activation.", "journal": "Molecular cell", "date": "2001-09", "authors": "Sabbagh W, Flatauer L J, Bardwell A J, Bardwell L", "evidence": [ { "database": "UniProtKB", "id": "P16892", "url": "https://www.uniprot.org/uniprotkb/P16892" }, { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" } ], "reference": [ { "type": "PubMed", "id": "11583629", "url": "https://glygen.org/publication/PubMed/11583629" } ] }, { "title": "A conserved protein interaction network involving the yeast MAP kinases Fus3 and Kss1.", "journal": "The Journal of cell biology", "date": "2004-01-19", "authors": "Kusari Anasua B, Molina Douglas M, Sabbagh Walid, Lau Chang S, Bardwell Lee", "evidence": [ { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" } ], "reference": [ { "type": "PubMed", "id": "14734536", "url": "https://glygen.org/publication/PubMed/14734536" } ] }, { "title": "Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.", "journal": "Molecular & cellular proteomics : MCP", "date": "2005-03", "authors": "Gruhler Albrecht, Olsen Jesper V, Mohammed Shabaz, Mortensen Peter, Faergeman Nils J, Mann Matthias, Jensen Ole N", "evidence": [ { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" } ], "reference": [ { "type": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" } ] }, { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "J. Proteome Res.", "date": "2007", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "UniProtKB", "id": "P16892", "url": "https://www.uniprot.org/uniprotkb/P16892" }, { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Mol. Cell. Proteomics", "date": "2008", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P16892", "url": "https://www.uniprot.org/uniprotkb/P16892" }, { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "MAP kinase-related FUS3 from S. cerevisiae is activated by STE7 in vitro.", "journal": "Nature", "date": "1993-03-18", "authors": "Errede B, Gartner A, Zhou Z, Nasmyth K, Ammerer G", "evidence": [ { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" } ], "reference": [ { "type": "PubMed", "id": "8384702", "url": "https://glygen.org/publication/PubMed/8384702" } ] }, { "title": "Pheromone-induced signal transduction in Saccharomyces cerevisiae requires the sequential function of three protein kinases.", "journal": "Molecular and cellular biology", "date": "1993-04", "authors": "Zhou Z, Gartner A, Cade R, Ammerer G, Errede B", "evidence": [ { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" } ], "reference": [ { "type": "PubMed", "id": "8455599", "url": "https://glygen.org/publication/PubMed/8455599" } ] }, { "title": "Differential regulation of FUS3 MAP kinase by tyrosine-specific phosphatases PTP2/PTP3 and dual-specificity phosphatase MSG5 in Saccharomyces cerevisiae.", "journal": "Genes & development", "date": "1997-07-01", "authors": "Zhan X L, Deschenes R J, Guan K L", "evidence": [ { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" } ], "reference": [ { "type": "PubMed", "id": "9224718", "url": "https://glygen.org/publication/PubMed/9224718" } ] }, { "title": "Quantitative profiling of dual phosphorylation of Fus3 MAP kinase in Saccharomyces cerevisiae.", "journal": "Molecules and cells", "date": "2008-07-31", "authors": "Hur Jae-Young, Kang Gum-Yong, Choi Min-Yeon, Jung Jin Woo, Kim Kwang-Pyo, Park Sang-Hyun", "evidence": [ { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" } ], "reference": [ { "type": "PubMed", "id": "18596411", "url": "https://glygen.org/publication/PubMed/18596411" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Design of a MAPK signalling cascade balances energetic cost versus accuracy of information transmission.", "journal": "Nature communications", "date": "2020-07-13", "authors": "Anders Alexander, Ghosh Bhaswar, Glatter Timo, Sourjik Victor", "evidence": [ { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" } ], "reference": [ { "type": "PubMed", "id": "32661402", "url": "https://glygen.org/publication/PubMed/32661402" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P16892", "url": "https://www.uniprot.org/uniprotkb/P16892", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "1628831", "url": "https://glygen.org/publication/PubMed/1628831", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "11583629", "url": "https://glygen.org/publication/PubMed/11583629", "database": "PubMed", "categories": [ "Other" ] }, { "id": "14734536", "url": "https://glygen.org/publication/PubMed/14734536", "database": "PubMed", "categories": [ "Other" ] }, { "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "8384702", "url": "https://glygen.org/publication/PubMed/8384702", "database": "PubMed", "categories": [ "Other" ] }, { "id": "8455599", "url": "https://glygen.org/publication/PubMed/8455599", "database": "PubMed", "categories": [ "Other" ] }, { "id": "9224718", "url": "https://glygen.org/publication/PubMed/9224718", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000112", "url": "https://www.yeastgenome.org/locus/S000000112", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "18596411", "url": "https://glygen.org/publication/PubMed/18596411", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32661402", "url": "https://glygen.org/publication/PubMed/32661402", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "IDESAADNSEPTGQQSGMTE", "down_seq": "VATRWYRAPEVMLTSAKYSR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "P16892", "url": "https://www.uniprot.org/uniprotkb/P16892" }, { "database": "PubMed", "id": "1628831", "url": "https://glygen.org/publication/PubMed/1628831" }, { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" }, { "database": "PubMed", "id": "11583629", "url": "https://glygen.org/publication/PubMed/11583629" }, { "database": "PubMed", "id": "14734536", "url": "https://glygen.org/publication/PubMed/14734536" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "8384702", "url": "https://glygen.org/publication/PubMed/8384702" }, { "database": "PubMed", "id": "8455599", "url": "https://glygen.org/publication/PubMed/8455599" }, { "database": "PubMed", "id": "9224718", "url": "https://glygen.org/publication/PubMed/9224718" }, { "database": "SGD", "id": "S000000112", "url": "https://www.yeastgenome.org/locus/S000000112" }, { "database": "PubMed", "id": "18596411", "url": "https://glygen.org/publication/PubMed/18596411" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "32661402", "url": "https://glygen.org/publication/PubMed/32661402" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Tyr182" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "262", "end_pos": "262" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "P16892-1.173.173", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P16892-1.177.177", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P16892-1.180.180", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P16892-1.197.197", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 15 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P16892-1.197.197", "start_pos": 197, "end_pos": 197, "uniprot_canonical_ac": "P16892-1", "length": 353, "uniprot_id": "FUS3_YEAST", "protein_name": "Mitogen-activated protein kinase FUS3", "refseq_ac": "NP_009537", "refseq_name": "mitogen-activated serine/threonine-protein kinase FUS3", "gene_name": "FUS3", "gene_names_uniprotkb": "FUS3; DAC2; YBL03.21; YBL0303", "gene_names_refseq": "DAC2; FUS3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P16892", "url": "https://www.uniprot.org/uniprotkb/P16892" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000112", "url": "https://www.yeastgenome.org/locus/S000000112", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SGMTEYVATRWYRAPEVMLT", "down_seq": "AKYSRAMDVWSCGCILAELF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000112", "url": "https://www.yeastgenome.org/locus/S000000112" }, { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser197" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "262", "end_pos": "262" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P16892-1.177.177", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P16892-1.180.180", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P16892-1.182.182", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P16892-1.262.262", "start_pos": 262, "end_pos": 262, "uniprot_canonical_ac": "P16892-1", "length": 353, "uniprot_id": "FUS3_YEAST", "protein_name": "Mitogen-activated protein kinase FUS3", "refseq_ac": "NP_009537", "refseq_name": "mitogen-activated serine/threonine-protein kinase FUS3", "gene_name": "FUS3", "gene_names_uniprotkb": "FUS3; DAC2; YBL03.21; YBL0303", "gene_names_refseq": "DAC2; FUS3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P16892", "url": "https://www.uniprot.org/uniprotkb/P16892" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000000112", "url": "https://www.yeastgenome.org/locus/S000000112", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PHSDNDLRCIESPRAREYIK", "down_seq": "LPMYPAAPLEKMFPRVNPKG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000112", "url": "https://www.yeastgenome.org/locus/S000000112" }, { "database": "iPTMnet", "id": "P16892", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16892" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser262" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "182", "end_pos": "182" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "262", "end_pos": "262" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17065-1.483.483", "start_pos": 483, "end_pos": 483, "uniprot_canonical_ac": "P17065-1", "length": 759, "uniprot_id": "SEC2_YEAST", "protein_name": "Rab guanine nucleotide exchange factor SEC2", "refseq_ac": "NP_014127", "refseq_name": "guanine nucleotide exchange factor SEC2", "gene_name": "SEC2", "gene_names_uniprotkb": "SEC2; N0641", "gene_names_refseq": "SEC2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "The role of the COOH terminus of Sec2p in the transport of post-Golgi vesicles.", "journal": "The Journal of cell biology", "date": "2000", "authors": "Elkind NB, Walch-Solimena C, Novick PJ", "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" } ], "reference": [ { "type": "PubMed", "id": "10747090", "url": "https://glygen.org/publication/PubMed/10747090" } ] } ], "crossref": [ { "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10747090", "url": "https://glygen.org/publication/PubMed/10747090", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "ETNAKPGQPTTNIQRAWLQL", "down_seq": "KLRCILHWTHIGIWAVDDSI", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "Y", "comment": "In SEC2-78; temperature-sensitive; causes mislocalization of the protein, displaying many cytoplasmic punctae.", "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" }, { "database": "PubMed", "id": "10747090", "url": "https://glygen.org/publication/PubMed/10747090" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "515", "end_pos": "515" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "542", "end_pos": "542" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "544", "end_pos": "544" }, { "start_pos": "545", "end_pos": "545" }, { "start_pos": "552", "end_pos": "552" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "705", "end_pos": "705" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "724", "end_pos": "724" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "747", "end_pos": "747" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17065-1.11.11", "start_pos": 11, "end_pos": 11, "uniprot_canonical_ac": "P17065-1", "length": 759, "uniprot_id": "SEC2_YEAST", "protein_name": "Rab guanine nucleotide exchange factor SEC2", "refseq_ac": "NP_014127", "refseq_name": "guanine nucleotide exchange factor SEC2", "gene_name": "SEC2", "gene_names_uniprotkb": "SEC2; N0641", "gene_names_refseq": "SEC2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global mapping of protein phosphorylation events identifies Ste20, Sch9 and the cell-cycle regulatory kinases Cdc28/Pho85 as mediators of fatty acid starvation responses in Saccharomyces cerevisiae.", "journal": "Molecular bioSystems", "date": "2012-03", "authors": "Pultz Dennis, Bennetzen Martin V, R\u00f8dk\u00e6r Steven Vestergaard, Zimmermann Christine, Enserink Jorrit M, Andersen Jens S, F\u00e6rgeman Nils J", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" } ] } ], "crossref": [ { "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MDASEEAKRV", "down_seq": "IQVTSLSTQLIESVDKQSHL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" } ], "site_lbl": "Ser11" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "515", "end_pos": "515" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "542", "end_pos": "542" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "544", "end_pos": "544" }, { "start_pos": "545", "end_pos": "545" }, { "start_pos": "552", "end_pos": "552" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "705", "end_pos": "705" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "724", "end_pos": "724" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "747", "end_pos": "747" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P17065-1.4.4", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P17065-1.24.24", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17065-1.168.168", "start_pos": 168, "end_pos": 168, "uniprot_canonical_ac": "P17065-1", "length": 759, "uniprot_id": "SEC2_YEAST", "protein_name": "Rab guanine nucleotide exchange factor SEC2", "refseq_ac": "NP_014127", "refseq_name": "guanine nucleotide exchange factor SEC2", "gene_name": "SEC2", "gene_names_uniprotkb": "SEC2; N0641", "gene_names_refseq": "SEC2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] } ], "crossref": [ { "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "TLQLKNLKKVMHSLDNESTV", "down_seq": "NNSNRYSTILSDSATSSSTS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" }, { "database": "SGD", "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216" } ], "site_lbl": "Thr168" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "515", "end_pos": "515" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "542", "end_pos": "542" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "544", "end_pos": "544" }, { "start_pos": "545", "end_pos": "545" }, { "start_pos": "552", "end_pos": "552" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "705", "end_pos": "705" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "724", "end_pos": "724" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "747", "end_pos": "747" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "P17065-1.171.171", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P17065-1.181.181", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P17065-1.183.183", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P17065-1.184.184", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P17065-1.185.185", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P17065-1.186.186", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P17065-1.188.188", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17065-1.171.171", "start_pos": 171, "end_pos": 171, "uniprot_canonical_ac": "P17065-1", "length": 759, "uniprot_id": "SEC2_YEAST", "protein_name": "Rab guanine nucleotide exchange factor SEC2", "refseq_ac": "NP_014127", "refseq_name": "guanine nucleotide exchange factor SEC2", "gene_name": "SEC2", "gene_names_uniprotkb": "SEC2; N0641", "gene_names_refseq": "SEC2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LKNLKKVMHSLDNESTVTNN", "down_seq": "NRYSTILSDSATSSSTSLNK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" }, { "database": "SGD", "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser171" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "515", "end_pos": "515" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "542", "end_pos": "542" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "544", "end_pos": "544" }, { "start_pos": "545", "end_pos": "545" }, { "start_pos": "552", "end_pos": "552" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "705", "end_pos": "705" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "724", "end_pos": "724" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "747", "end_pos": "747" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P17065-1.168.168", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P17065-1.181.181", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P17065-1.183.183", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P17065-1.184.184", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P17065-1.185.185", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P17065-1.186.186", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P17065-1.188.188", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17065-1.181.181", "start_pos": 181, "end_pos": 181, "uniprot_canonical_ac": "P17065-1", "length": 759, "uniprot_id": "SEC2_YEAST", "protein_name": "Rab guanine nucleotide exchange factor SEC2", "refseq_ac": "NP_014127", "refseq_name": "guanine nucleotide exchange factor SEC2", "gene_name": "SEC2", "gene_names_uniprotkb": "SEC2; N0641", "gene_names_refseq": "SEC2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LDNESTVTNNSNRYSTILSD", "down_seq": "ATSSSTSLNKVPTSYSLASQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser181" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "515", "end_pos": "515" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "542", "end_pos": "542" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "544", "end_pos": "544" }, { "start_pos": "545", "end_pos": "545" }, { "start_pos": "552", "end_pos": "552" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "705", "end_pos": "705" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "724", "end_pos": "724" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "747", "end_pos": "747" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P17065-1.168.168", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P17065-1.171.171", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P17065-1.183.183", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P17065-1.184.184", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P17065-1.185.185", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P17065-1.186.186", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P17065-1.188.188", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P17065-1.197.197", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P17065-1.200.200", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17065-1.183.183", "start_pos": 183, "end_pos": 183, "uniprot_canonical_ac": "P17065-1", "length": 759, "uniprot_id": "SEC2_YEAST", "protein_name": "Rab guanine nucleotide exchange factor SEC2", "refseq_ac": "NP_014127", "refseq_name": "guanine nucleotide exchange factor SEC2", "gene_name": "SEC2", "gene_names_uniprotkb": "SEC2; N0641", "gene_names_refseq": "SEC2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "NESTVTNNSNRYSTILSDSA", "down_seq": "SSSTSLNKVPTSYSLASQDI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr183" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "515", "end_pos": "515" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "542", "end_pos": "542" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "544", "end_pos": "544" }, { "start_pos": "545", "end_pos": "545" }, { "start_pos": "552", "end_pos": "552" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "705", "end_pos": "705" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "724", "end_pos": "724" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "747", "end_pos": "747" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P17065-1.168.168", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P17065-1.171.171", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P17065-1.181.181", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P17065-1.184.184", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P17065-1.185.185", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P17065-1.186.186", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P17065-1.188.188", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P17065-1.197.197", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P17065-1.200.200", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17065-1.184.184", "start_pos": 184, "end_pos": 184, "uniprot_canonical_ac": "P17065-1", "length": 759, "uniprot_id": "SEC2_YEAST", "protein_name": "Rab guanine nucleotide exchange factor SEC2", "refseq_ac": "NP_014127", "refseq_name": "guanine nucleotide exchange factor SEC2", "gene_name": "SEC2", "gene_names_uniprotkb": "SEC2; N0641", "gene_names_refseq": "SEC2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ESTVTNNSNRYSTILSDSAT", "down_seq": "SSTSLNKVPTSYSLASQDIY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser184" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "515", "end_pos": "515" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "542", "end_pos": "542" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "544", "end_pos": "544" }, { "start_pos": "545", "end_pos": "545" }, { "start_pos": "552", "end_pos": "552" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "705", "end_pos": "705" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "724", "end_pos": "724" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "747", "end_pos": "747" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P17065-1.168.168", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P17065-1.171.171", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P17065-1.181.181", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P17065-1.183.183", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P17065-1.185.185", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P17065-1.186.186", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P17065-1.188.188", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P17065-1.197.197", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P17065-1.200.200", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P17065-1.204.204", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17065-1.185.185", "start_pos": 185, "end_pos": 185, "uniprot_canonical_ac": "P17065-1", "length": 759, "uniprot_id": "SEC2_YEAST", "protein_name": "Rab guanine nucleotide exchange factor SEC2", "refseq_ac": "NP_014127", "refseq_name": "guanine nucleotide exchange factor SEC2", "gene_name": "SEC2", "gene_names_uniprotkb": "SEC2; N0641", "gene_names_refseq": "SEC2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "STVTNNSNRYSTILSDSATS", "down_seq": "STSLNKVPTSYSLASQDIYS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser185" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "515", "end_pos": "515" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "542", "end_pos": "542" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "544", "end_pos": "544" }, { "start_pos": "545", "end_pos": "545" }, { "start_pos": "552", "end_pos": "552" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "705", "end_pos": "705" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "724", "end_pos": "724" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "747", "end_pos": "747" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P17065-1.168.168", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P17065-1.171.171", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P17065-1.181.181", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P17065-1.183.183", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P17065-1.184.184", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P17065-1.186.186", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P17065-1.188.188", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P17065-1.197.197", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P17065-1.200.200", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P17065-1.204.204", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17065-1.186.186", "start_pos": 186, "end_pos": 186, "uniprot_canonical_ac": "P17065-1", "length": 759, "uniprot_id": "SEC2_YEAST", "protein_name": "Rab guanine nucleotide exchange factor SEC2", "refseq_ac": "NP_014127", "refseq_name": "guanine nucleotide exchange factor SEC2", "gene_name": "SEC2", "gene_names_uniprotkb": "SEC2; N0641", "gene_names_refseq": "SEC2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TVTNNSNRYSTILSDSATSS", "down_seq": "TSLNKVPTSYSLASQDIYSG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser186" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "515", "end_pos": "515" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "542", "end_pos": "542" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "544", "end_pos": "544" }, { "start_pos": "545", "end_pos": "545" }, { "start_pos": "552", "end_pos": "552" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "705", "end_pos": "705" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "724", "end_pos": "724" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "747", "end_pos": "747" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P17065-1.168.168", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P17065-1.171.171", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P17065-1.181.181", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P17065-1.183.183", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P17065-1.184.184", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P17065-1.185.185", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P17065-1.188.188", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P17065-1.197.197", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P17065-1.200.200", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P17065-1.204.204", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17065-1.188.188", "start_pos": 188, "end_pos": 188, "uniprot_canonical_ac": "P17065-1", "length": 759, "uniprot_id": "SEC2_YEAST", "protein_name": "Rab guanine nucleotide exchange factor SEC2", "refseq_ac": "NP_014127", "refseq_name": "guanine nucleotide exchange factor SEC2", "gene_name": "SEC2", "gene_names_uniprotkb": "SEC2; N0641", "gene_names_refseq": "SEC2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TNNSNRYSTILSDSATSSST", "down_seq": "LNKVPTSYSLASQDIYSGIV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser188" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "515", "end_pos": "515" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "542", "end_pos": "542" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "544", "end_pos": "544" }, { "start_pos": "545", "end_pos": "545" }, { "start_pos": "552", "end_pos": "552" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "705", "end_pos": "705" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "724", "end_pos": "724" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "747", "end_pos": "747" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P17065-1.168.168", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P17065-1.171.171", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P17065-1.181.181", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P17065-1.183.183", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P17065-1.184.184", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P17065-1.185.185", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P17065-1.186.186", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P17065-1.197.197", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P17065-1.200.200", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P17065-1.204.204", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17065-1.197.197", "start_pos": 197, "end_pos": 197, "uniprot_canonical_ac": "P17065-1", "length": 759, "uniprot_id": "SEC2_YEAST", "protein_name": "Rab guanine nucleotide exchange factor SEC2", "refseq_ac": "NP_014127", "refseq_name": "guanine nucleotide exchange factor SEC2", "gene_name": "SEC2", "gene_names_uniprotkb": "SEC2; N0641", "gene_names_refseq": "SEC2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ILSDSATSSSTSLNKVPTSY", "down_seq": "LASQDIYSGIVYSPSISSIR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser197" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "515", "end_pos": "515" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "542", "end_pos": "542" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "544", "end_pos": "544" }, { "start_pos": "545", "end_pos": "545" }, { "start_pos": "552", "end_pos": "552" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "705", "end_pos": "705" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "724", "end_pos": "724" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "747", "end_pos": "747" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P17065-1.181.181", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P17065-1.183.183", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P17065-1.184.184", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P17065-1.185.185", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P17065-1.186.186", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P17065-1.188.188", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P17065-1.200.200", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P17065-1.204.204", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17065-1.200.200", "start_pos": 200, "end_pos": 200, "uniprot_canonical_ac": "P17065-1", "length": 759, "uniprot_id": "SEC2_YEAST", "protein_name": "Rab guanine nucleotide exchange factor SEC2", "refseq_ac": "NP_014127", "refseq_name": "guanine nucleotide exchange factor SEC2", "gene_name": "SEC2", "gene_names_uniprotkb": "SEC2; N0641", "gene_names_refseq": "SEC2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ], "crossref": [ { "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DSATSSSTSLNKVPTSYSLA", "down_seq": "QDIYSGIVYSPSISSIRYDI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216" } ], "site_lbl": "Ser200" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "515", "end_pos": "515" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "542", "end_pos": "542" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "544", "end_pos": "544" }, { "start_pos": "545", "end_pos": "545" }, { "start_pos": "552", "end_pos": "552" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "705", "end_pos": "705" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "724", "end_pos": "724" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "747", "end_pos": "747" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P17065-1.181.181", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P17065-1.183.183", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P17065-1.184.184", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P17065-1.185.185", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P17065-1.186.186", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P17065-1.188.188", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P17065-1.197.197", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P17065-1.204.204", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17065-1.204.204", "start_pos": 204, "end_pos": 204, "uniprot_canonical_ac": "P17065-1", "length": 759, "uniprot_id": "SEC2_YEAST", "protein_name": "Rab guanine nucleotide exchange factor SEC2", "refseq_ac": "NP_014127", "refseq_name": "guanine nucleotide exchange factor SEC2", "gene_name": "SEC2", "gene_names_uniprotkb": "SEC2; N0641", "gene_names_refseq": "SEC2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ], "crossref": [ { "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "SSSTSLNKVPTSYSLASQDI", "down_seq": "SGIVYSPSISSIRYDISLYN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ], "site_lbl": "Tyr204" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "515", "end_pos": "515" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "542", "end_pos": "542" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "544", "end_pos": "544" }, { "start_pos": "545", "end_pos": "545" }, { "start_pos": "552", "end_pos": "552" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "705", "end_pos": "705" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "724", "end_pos": "724" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "747", "end_pos": "747" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P17065-1.184.184", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "downstream", "id": "P17065-1.185.185", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "downstream", "id": "P17065-1.186.186", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P17065-1.188.188", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P17065-1.197.197", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P17065-1.200.200", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17065-1.24.24", "start_pos": 24, "end_pos": 24, "uniprot_canonical_ac": "P17065-1", "length": 759, "uniprot_id": "SEC2_YEAST", "protein_name": "Rab guanine nucleotide exchange factor SEC2", "refseq_ac": "NP_014127", "refseq_name": "guanine nucleotide exchange factor SEC2", "gene_name": "SEC2", "gene_names_uniprotkb": "SEC2; N0641", "gene_names_refseq": "SEC2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global mapping of protein phosphorylation events identifies Ste20, Sch9 and the cell-cycle regulatory kinases Cdc28/Pho85 as mediators of fatty acid starvation responses in Saccharomyces cerevisiae.", "journal": "Molecular bioSystems", "date": "2012-03", "authors": "Pultz Dennis, Bennetzen Martin V, R\u00f8dk\u00e6r Steven Vestergaard, Zimmermann Christine, Enserink Jorrit M, Andersen Jens S, F\u00e6rgeman Nils J", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" } ] } ], "crossref": [ { "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SEEAKRVSIQVTSLSTQLIE", "down_seq": "VDKQSHLEEQLNKSLKTIAS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" } ], "site_lbl": "Ser24" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "515", "end_pos": "515" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "542", "end_pos": "542" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "544", "end_pos": "544" }, { "start_pos": "545", "end_pos": "545" }, { "start_pos": "552", "end_pos": "552" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "705", "end_pos": "705" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "724", "end_pos": "724" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "747", "end_pos": "747" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P17065-1.4.4", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P17065-1.11.11", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17065-1.306.306", "start_pos": 306, "end_pos": 306, "uniprot_canonical_ac": "P17065-1", "length": 759, "uniprot_id": "SEC2_YEAST", "protein_name": "Rab guanine nucleotide exchange factor SEC2", "refseq_ac": "NP_014127", "refseq_name": "guanine nucleotide exchange factor SEC2", "gene_name": "SEC2", "gene_names_uniprotkb": "SEC2; N0641", "gene_names_refseq": "SEC2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VVVEPLSGVNATYQIGYNSS", "down_seq": "PAKQATSNMPKMFKFPLDSP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser306" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "515", "end_pos": "515" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "542", "end_pos": "542" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "544", "end_pos": "544" }, { "start_pos": "545", "end_pos": "545" }, { "start_pos": "552", "end_pos": "552" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "705", "end_pos": "705" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "724", "end_pos": "724" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "747", "end_pos": "747" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17065-1.409.409", "start_pos": 409, "end_pos": 409, "uniprot_canonical_ac": "P17065-1", "length": 759, "uniprot_id": "SEC2_YEAST", "protein_name": "Rab guanine nucleotide exchange factor SEC2", "refseq_ac": "NP_014127", "refseq_name": "guanine nucleotide exchange factor SEC2", "gene_name": "SEC2", "gene_names_uniprotkb": "SEC2; N0641", "gene_names_refseq": "SEC2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "FLRSLKVGAWHLEKLTTQNI", "down_seq": "KEDLEKFSEVTKHTKRDGRV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr409" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "515", "end_pos": "515" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "542", "end_pos": "542" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "544", "end_pos": "544" }, { "start_pos": "545", "end_pos": "545" }, { "start_pos": "552", "end_pos": "552" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "705", "end_pos": "705" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "724", "end_pos": "724" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "747", "end_pos": "747" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17065-1.4.4", "start_pos": 4, "end_pos": 4, "uniprot_canonical_ac": "P17065-1", "length": 759, "uniprot_id": "SEC2_YEAST", "protein_name": "Rab guanine nucleotide exchange factor SEC2", "refseq_ac": "NP_014127", "refseq_name": "guanine nucleotide exchange factor SEC2", "gene_name": "SEC2", "gene_names_uniprotkb": "SEC2; N0641", "gene_names_refseq": "SEC2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MDA", "down_seq": "EEAKRVSIQVTSLSTQLIES", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser4" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "515", "end_pos": "515" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "542", "end_pos": "542" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "544", "end_pos": "544" }, { "start_pos": "545", "end_pos": "545" }, { "start_pos": "552", "end_pos": "552" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "705", "end_pos": "705" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "724", "end_pos": "724" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "747", "end_pos": "747" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "upstream", "id": "P17065-1.11.11", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P17065-1.24.24", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17065-1.515.515", "start_pos": 515, "end_pos": 515, "uniprot_canonical_ac": "P17065-1", "length": 759, "uniprot_id": "SEC2_YEAST", "protein_name": "Rab guanine nucleotide exchange factor SEC2", "refseq_ac": "NP_014127", "refseq_name": "guanine nucleotide exchange factor SEC2", "gene_name": "SEC2", "gene_names_uniprotkb": "SEC2; N0641", "gene_names_refseq": "SEC2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "Journal of proteome research", "date": "2007-03", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.", "journal": "Genes & development", "date": "2009-08-15", "authors": "Huber Alexandre, Bodenmiller Bernd, Uotila Aino, Stahl Michael, Wanka Stefanie, Gerrits Bertran, Aebersold Ruedi, Loewith Robbie", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] }, { "title": "High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast.", "journal": "Proteomics", "date": "2009-10", "authors": "Gnad Florian, de Godoy Lyris M F, Cox J\u00fcrgen, Neuhauser Nadin, Ren Shubin, Olsen Jesper V, Mann Matthias", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" } ] }, { "title": "Global analysis of the yeast osmotic stress response by quantitative proteomics.", "journal": "Molecular bioSystems", "date": "2009-11", "authors": "Soufi Boumediene, Kelstrup Christian D, Stoehr Gabriele, Fr\u00f6hlich Florian, Walther Tobias C, Olsen Jesper V", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] }, { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] }, { "title": "Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast.", "journal": "Science signaling", "date": "2010-12-21", "authors": "Bodenmiller Bernd, Wanka Stefanie, Kraft Claudine, Urban J\u00f6rg, Campbell David, Pedrioli Patrick G, Gerrits Bertran, Picotti Paola, Lam Henry, Vitek Olga, Brusniak Mi-Youn, Roschitzki Bernd, Zhang Chao, Shokat Kevan M, Schlapbach Ralph, Colman-Lerner Alejandro, Nolan Garry P, Nesvizhskii Alexey I, Peter Matthias, Loewith Robbie, von Mering Christian, Aebersold Ruedi", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "title": "Global mapping of protein phosphorylation events identifies Ste20, Sch9 and the cell-cycle regulatory kinases Cdc28/Pho85 as mediators of fatty acid starvation responses in Saccharomyces cerevisiae.", "journal": "Molecular bioSystems", "date": "2012-03", "authors": "Pultz Dennis, Bennetzen Martin V, R\u00f8dk\u00e6r Steven Vestergaard, Zimmermann Christine, Enserink Jorrit M, Andersen Jens S, F\u00e6rgeman Nils J", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GIWAVDDSISSKIGPLVEDD", "down_seq": "DEDQNDAISVRLQDKALWKQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser515" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "515", "end_pos": "515" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "542", "end_pos": "542" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "544", "end_pos": "544" }, { "start_pos": "545", "end_pos": "545" }, { "start_pos": "552", "end_pos": "552" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "705", "end_pos": "705" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "724", "end_pos": "724" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "747", "end_pos": "747" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "upstream", "id": "P17065-1.524.524", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 13 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17065-1.524.524", "start_pos": 524, "end_pos": 524, "uniprot_canonical_ac": "P17065-1", "length": 759, "uniprot_id": "SEC2_YEAST", "protein_name": "Rab guanine nucleotide exchange factor SEC2", "refseq_ac": "NP_014127", "refseq_name": "guanine nucleotide exchange factor SEC2", "gene_name": "SEC2", "gene_names_uniprotkb": "SEC2; N0641", "gene_names_refseq": "SEC2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "Journal of proteome research", "date": "2007-03", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.", "journal": "Genes & development", "date": "2009-08-15", "authors": "Huber Alexandre, Bodenmiller Bernd, Uotila Aino, Stahl Michael, Wanka Stefanie, Gerrits Bertran, Aebersold Ruedi, Loewith Robbie", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SSKIGPLVEDDSDEDQNDAI", "down_seq": "VRLQDKALWKQDAKRPFSSS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser524" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "515", "end_pos": "515" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "542", "end_pos": "542" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "544", "end_pos": "544" }, { "start_pos": "545", "end_pos": "545" }, { "start_pos": "552", "end_pos": "552" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "705", "end_pos": "705" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "724", "end_pos": "724" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "747", "end_pos": "747" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "P17065-1.515.515", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P17065-1.542.542", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P17065-1.543.543", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P17065-1.544.544", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17065-1.542.542", "start_pos": 542, "end_pos": 542, "uniprot_canonical_ac": "P17065-1", "length": 759, "uniprot_id": "SEC2_YEAST", "protein_name": "Rab guanine nucleotide exchange factor SEC2", "refseq_ac": "NP_014127", "refseq_name": "guanine nucleotide exchange factor SEC2", "gene_name": "SEC2", "gene_names_uniprotkb": "SEC2; N0641", "gene_names_refseq": "SEC2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AISVRLQDKALWKQDAKRPF", "down_seq": "SSSAEESQKSDAFDFESGDM", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser542" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "515", "end_pos": "515" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "542", "end_pos": "542" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "544", "end_pos": "544" }, { "start_pos": "545", "end_pos": "545" }, { "start_pos": "552", "end_pos": "552" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "705", "end_pos": "705" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "724", "end_pos": "724" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "747", "end_pos": "747" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P17065-1.524.524", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P17065-1.543.543", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P17065-1.544.544", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P17065-1.545.545", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P17065-1.552.552", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17065-1.543.543", "start_pos": 543, "end_pos": 543, "uniprot_canonical_ac": "P17065-1", "length": 759, "uniprot_id": "SEC2_YEAST", "protein_name": "Rab guanine nucleotide exchange factor SEC2", "refseq_ac": "NP_014127", "refseq_name": "guanine nucleotide exchange factor SEC2", "gene_name": "SEC2", "gene_names_uniprotkb": "SEC2; N0641", "gene_names_refseq": "SEC2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ISVRLQDKALWKQDAKRPFS", "down_seq": "SSAEESQKSDAFDFESGDME", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser543" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "515", "end_pos": "515" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "542", "end_pos": "542" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "544", "end_pos": "544" }, { "start_pos": "545", "end_pos": "545" }, { "start_pos": "552", "end_pos": "552" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "705", "end_pos": "705" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "724", "end_pos": "724" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "747", "end_pos": "747" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P17065-1.524.524", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P17065-1.542.542", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P17065-1.544.544", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P17065-1.545.545", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P17065-1.552.552", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17065-1.544.544", "start_pos": 544, "end_pos": 544, "uniprot_canonical_ac": "P17065-1", "length": 759, "uniprot_id": "SEC2_YEAST", "protein_name": "Rab guanine nucleotide exchange factor SEC2", "refseq_ac": "NP_014127", "refseq_name": "guanine nucleotide exchange factor SEC2", "gene_name": "SEC2", "gene_names_uniprotkb": "SEC2; N0641", "gene_names_refseq": "SEC2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-06-19", "authors": "Smolka Marcus B, Albuquerque Claudio P, Chen Sheng-hong, Zhou Huilin", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] }, { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SVRLQDKALWKQDAKRPFSS", "down_seq": "SAEESQKSDAFDFESGDMEN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser544" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "515", "end_pos": "515" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "542", "end_pos": "542" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "544", "end_pos": "544" }, { "start_pos": "545", "end_pos": "545" }, { "start_pos": "552", "end_pos": "552" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "705", "end_pos": "705" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "724", "end_pos": "724" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "747", "end_pos": "747" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P17065-1.524.524", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P17065-1.542.542", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P17065-1.543.543", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P17065-1.545.545", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P17065-1.552.552", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17065-1.545.545", "start_pos": 545, "end_pos": 545, "uniprot_canonical_ac": "P17065-1", "length": 759, "uniprot_id": "SEC2_YEAST", "protein_name": "Rab guanine nucleotide exchange factor SEC2", "refseq_ac": "NP_014127", "refseq_name": "guanine nucleotide exchange factor SEC2", "gene_name": "SEC2", "gene_names_uniprotkb": "SEC2; N0641", "gene_names_refseq": "SEC2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-06-19", "authors": "Smolka Marcus B, Albuquerque Claudio P, Chen Sheng-hong, Zhou Huilin", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] }, { "title": "High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast.", "journal": "Proteomics", "date": "2009-10", "authors": "Gnad Florian, de Godoy Lyris M F, Cox J\u00fcrgen, Neuhauser Nadin, Ren Shubin, Olsen Jesper V, Mann Matthias", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" } ] }, { "title": "Global analysis of the yeast osmotic stress response by quantitative proteomics.", "journal": "Molecular bioSystems", "date": "2009-11", "authors": "Soufi Boumediene, Kelstrup Christian D, Stoehr Gabriele, Fr\u00f6hlich Florian, Walther Tobias C, Olsen Jesper V", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VRLQDKALWKQDAKRPFSSS", "down_seq": "AEESQKSDAFDFESGDMENE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser545" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "515", "end_pos": "515" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "542", "end_pos": "542" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "544", "end_pos": "544" }, { "start_pos": "545", "end_pos": "545" }, { "start_pos": "552", "end_pos": "552" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "705", "end_pos": "705" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "724", "end_pos": "724" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "747", "end_pos": "747" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P17065-1.542.542", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P17065-1.543.543", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P17065-1.544.544", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P17065-1.552.552", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17065-1.552.552", "start_pos": 552, "end_pos": 552, "uniprot_canonical_ac": "P17065-1", "length": 759, "uniprot_id": "SEC2_YEAST", "protein_name": "Rab guanine nucleotide exchange factor SEC2", "refseq_ac": "NP_014127", "refseq_name": "guanine nucleotide exchange factor SEC2", "gene_name": "SEC2", "gene_names_uniprotkb": "SEC2; N0641", "gene_names_refseq": "SEC2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LWKQDAKRPFSSSSAEESQK", "down_seq": "DAFDFESGDMENEITGESSS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser552" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "515", "end_pos": "515" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "542", "end_pos": "542" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "544", "end_pos": "544" }, { "start_pos": "545", "end_pos": "545" }, { "start_pos": "552", "end_pos": "552" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "705", "end_pos": "705" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "724", "end_pos": "724" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "747", "end_pos": "747" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "P17065-1.542.542", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P17065-1.543.543", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P17065-1.544.544", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P17065-1.545.545", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17065-1.629.629", "start_pos": 629, "end_pos": 629, "uniprot_canonical_ac": "P17065-1", "length": 759, "uniprot_id": "SEC2_YEAST", "protein_name": "Rab guanine nucleotide exchange factor SEC2", "refseq_ac": "NP_014127", "refseq_name": "guanine nucleotide exchange factor SEC2", "gene_name": "SEC2", "gene_names_uniprotkb": "SEC2; N0641", "gene_names_refseq": "SEC2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SPESIDNGEGDDTVTKDDKS", "down_seq": "IKSANNNEENSDCGDKKGRS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser629" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "515", "end_pos": "515" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "542", "end_pos": "542" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "544", "end_pos": "544" }, { "start_pos": "545", "end_pos": "545" }, { "start_pos": "552", "end_pos": "552" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "705", "end_pos": "705" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "724", "end_pos": "724" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "747", "end_pos": "747" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "P17065-1.632.632", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P17065-1.640.640", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17065-1.632.632", "start_pos": 632, "end_pos": 632, "uniprot_canonical_ac": "P17065-1", "length": 759, "uniprot_id": "SEC2_YEAST", "protein_name": "Rab guanine nucleotide exchange factor SEC2", "refseq_ac": "NP_014127", "refseq_name": "guanine nucleotide exchange factor SEC2", "gene_name": "SEC2", "gene_names_uniprotkb": "SEC2; N0641", "gene_names_refseq": "SEC2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SIDNGEGDDTVTKDDKSSIK", "down_seq": "ANNNEENSDCGDKKGRSIIK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser632" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "515", "end_pos": "515" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "542", "end_pos": "542" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "544", "end_pos": "544" }, { "start_pos": "545", "end_pos": "545" }, { "start_pos": "552", "end_pos": "552" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "705", "end_pos": "705" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "724", "end_pos": "724" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "747", "end_pos": "747" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P17065-1.629.629", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P17065-1.640.640", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17065-1.640.640", "start_pos": 640, "end_pos": 640, "uniprot_canonical_ac": "P17065-1", "length": 759, "uniprot_id": "SEC2_YEAST", "protein_name": "Rab guanine nucleotide exchange factor SEC2", "refseq_ac": "NP_014127", "refseq_name": "guanine nucleotide exchange factor SEC2", "gene_name": "SEC2", "gene_names_uniprotkb": "SEC2; N0641", "gene_names_refseq": "SEC2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DTVTKDDKSSIKSANNNEEN", "down_seq": "DCGDKKGRSIIKKKAPQRKI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser640" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "515", "end_pos": "515" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "542", "end_pos": "542" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "544", "end_pos": "544" }, { "start_pos": "545", "end_pos": "545" }, { "start_pos": "552", "end_pos": "552" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "705", "end_pos": "705" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "724", "end_pos": "724" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "747", "end_pos": "747" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P17065-1.629.629", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P17065-1.632.632", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17065-1.67.67", "start_pos": 67, "end_pos": 67, "uniprot_canonical_ac": "P17065-1", "length": 759, "uniprot_id": "SEC2_YEAST", "protein_name": "Rab guanine nucleotide exchange factor SEC2", "refseq_ac": "NP_014127", "refseq_name": "guanine nucleotide exchange factor SEC2", "gene_name": "SEC2", "gene_names_uniprotkb": "SEC2; N0641", "gene_names_refseq": "SEC2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AAIENYNQLKEDYNTLKREL", "down_seq": "DRDDEVKRLREDIAKENELR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser67" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "515", "end_pos": "515" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "542", "end_pos": "542" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "544", "end_pos": "544" }, { "start_pos": "545", "end_pos": "545" }, { "start_pos": "552", "end_pos": "552" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "705", "end_pos": "705" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "724", "end_pos": "724" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "747", "end_pos": "747" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17065-1.704.704", "start_pos": 704, "end_pos": 704, "uniprot_canonical_ac": "P17065-1", "length": 759, "uniprot_id": "SEC2_YEAST", "protein_name": "Rab guanine nucleotide exchange factor SEC2", "refseq_ac": "NP_014127", "refseq_name": "guanine nucleotide exchange factor SEC2", "gene_name": "SEC2", "gene_names_uniprotkb": "SEC2; N0641", "gene_names_refseq": "SEC2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QTEFENAESNVKQNISSKRA", "down_seq": "SGDENSKKDNNEKTLKTNLT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser704" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "515", "end_pos": "515" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "542", "end_pos": "542" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "544", "end_pos": "544" }, { "start_pos": "545", "end_pos": "545" }, { "start_pos": "552", "end_pos": "552" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "705", "end_pos": "705" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "724", "end_pos": "724" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "747", "end_pos": "747" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "P17065-1.705.705", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P17065-1.710.710", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P17065-1.724.724", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17065-1.705.705", "start_pos": 705, "end_pos": 705, "uniprot_canonical_ac": "P17065-1", "length": 759, "uniprot_id": "SEC2_YEAST", "protein_name": "Rab guanine nucleotide exchange factor SEC2", "refseq_ac": "NP_014127", "refseq_name": "guanine nucleotide exchange factor SEC2", "gene_name": "SEC2", "gene_names_uniprotkb": "SEC2; N0641", "gene_names_refseq": "SEC2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ], "crossref": [ { "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TEFENAESNVKQNISSKRAS", "down_seq": "GDENSKKDNNEKTLKTNLTI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ], "site_lbl": "Ser705" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "515", "end_pos": "515" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "542", "end_pos": "542" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "544", "end_pos": "544" }, { "start_pos": "545", "end_pos": "545" }, { "start_pos": "552", "end_pos": "552" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "705", "end_pos": "705" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "724", "end_pos": "724" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "747", "end_pos": "747" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "P17065-1.704.704", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P17065-1.710.710", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P17065-1.724.724", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17065-1.710.710", "start_pos": 710, "end_pos": 710, "uniprot_canonical_ac": "P17065-1", "length": 759, "uniprot_id": "SEC2_YEAST", "protein_name": "Rab guanine nucleotide exchange factor SEC2", "refseq_ac": "NP_014127", "refseq_name": "guanine nucleotide exchange factor SEC2", "gene_name": "SEC2", "gene_names_uniprotkb": "SEC2; N0641", "gene_names_refseq": "SEC2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast.", "journal": "Proteomics", "date": "2009-10", "authors": "Gnad Florian, de Godoy Lyris M F, Cox J\u00fcrgen, Neuhauser Nadin, Ren Shubin, Olsen Jesper V, Mann Matthias", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" } ] }, { "title": "Global analysis of the yeast osmotic stress response by quantitative proteomics.", "journal": "Molecular bioSystems", "date": "2009-11", "authors": "Soufi Boumediene, Kelstrup Christian D, Stoehr Gabriele, Fr\u00f6hlich Florian, Walther Tobias C, Olsen Jesper V", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AESNVKQNISSKRASSGDEN", "down_seq": "KKDNNEKTLKTNLTIGDKTQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser710" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "515", "end_pos": "515" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "542", "end_pos": "542" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "544", "end_pos": "544" }, { "start_pos": "545", "end_pos": "545" }, { "start_pos": "552", "end_pos": "552" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "705", "end_pos": "705" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "724", "end_pos": "724" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "747", "end_pos": "747" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "P17065-1.704.704", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P17065-1.705.705", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P17065-1.724.724", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17065-1.724.724", "start_pos": 724, "end_pos": 724, "uniprot_canonical_ac": "P17065-1", "length": 759, "uniprot_id": "SEC2_YEAST", "protein_name": "Rab guanine nucleotide exchange factor SEC2", "refseq_ac": "NP_014127", "refseq_name": "guanine nucleotide exchange factor SEC2", "gene_name": "SEC2", "gene_names_uniprotkb": "SEC2; N0641", "gene_names_refseq": "SEC2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SSGDENSKKDNNEKTLKTNL", "down_seq": "IGDKTQEQIGENSPSSGLHA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr724" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "515", "end_pos": "515" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "542", "end_pos": "542" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "544", "end_pos": "544" }, { "start_pos": "545", "end_pos": "545" }, { "start_pos": "552", "end_pos": "552" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "705", "end_pos": "705" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "724", "end_pos": "724" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "747", "end_pos": "747" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P17065-1.704.704", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "downstream", "id": "P17065-1.705.705", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P17065-1.710.710", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P17065-1.737.737", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17065-1.737.737", "start_pos": 737, "end_pos": 737, "uniprot_canonical_ac": "P17065-1", "length": 759, "uniprot_id": "SEC2_YEAST", "protein_name": "Rab guanine nucleotide exchange factor SEC2", "refseq_ac": "NP_014127", "refseq_name": "guanine nucleotide exchange factor SEC2", "gene_name": "SEC2", "gene_names_uniprotkb": "SEC2; N0641", "gene_names_refseq": "SEC2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KTLKTNLTIGDKTQEQIGEN", "down_seq": "PSSGLHASSSNDDNFDDAQE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser737" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "515", "end_pos": "515" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "542", "end_pos": "542" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "544", "end_pos": "544" }, { "start_pos": "545", "end_pos": "545" }, { "start_pos": "552", "end_pos": "552" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "705", "end_pos": "705" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "724", "end_pos": "724" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "747", "end_pos": "747" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P17065-1.724.724", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P17065-1.746.746", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P17065-1.747.747", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17065-1.746.746", "start_pos": 746, "end_pos": 746, "uniprot_canonical_ac": "P17065-1", "length": 759, "uniprot_id": "SEC2_YEAST", "protein_name": "Rab guanine nucleotide exchange factor SEC2", "refseq_ac": "NP_014127", "refseq_name": "guanine nucleotide exchange factor SEC2", "gene_name": "SEC2", "gene_names_uniprotkb": "SEC2; N0641", "gene_names_refseq": "SEC2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "crossref": [ { "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GDKTQEQIGENSPSSGLHAS", "down_seq": "SNDDNFDDAQEQQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Ser746" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "515", "end_pos": "515" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "542", "end_pos": "542" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "544", "end_pos": "544" }, { "start_pos": "545", "end_pos": "545" }, { "start_pos": "552", "end_pos": "552" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "705", "end_pos": "705" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "724", "end_pos": "724" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "747", "end_pos": "747" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "P17065-1.737.737", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P17065-1.747.747", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17065-1.747.747", "start_pos": 747, "end_pos": 747, "uniprot_canonical_ac": "P17065-1", "length": 759, "uniprot_id": "SEC2_YEAST", "protein_name": "Rab guanine nucleotide exchange factor SEC2", "refseq_ac": "NP_014127", "refseq_name": "guanine nucleotide exchange factor SEC2", "gene_name": "SEC2", "gene_names_uniprotkb": "SEC2; N0641", "gene_names_refseq": "SEC2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17065", "url": "https://www.uniprot.org/uniprotkb/P17065" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "crossref": [ { "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DKTQEQIGENSPSSGLHASS", "down_seq": "NDDNFDDAQEQQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005216", "url": "https://www.yeastgenome.org/locus/S000005216" }, { "database": "iPTMnet", "id": "P17065", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17065" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Ser747" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "515", "end_pos": "515" }, { "start_pos": "524", "end_pos": "524" }, { "start_pos": "542", "end_pos": "542" }, { "start_pos": "543", "end_pos": "543" }, { "start_pos": "544", "end_pos": "544" }, { "start_pos": "545", "end_pos": "545" }, { "start_pos": "552", "end_pos": "552" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "705", "end_pos": "705" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "724", "end_pos": "724" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "747", "end_pos": "747" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "P17065-1.737.737", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P17065-1.746.746", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17157-1.46.46", "start_pos": 46, "end_pos": 46, "uniprot_canonical_ac": "P17157-1", "length": 305, "uniprot_id": "PHO85_YEAST", "protein_name": "Cyclin-dependent protein kinase PHO85", "refseq_ac": "NP_015294", "refseq_name": "cyclin-dependent serine/threonine-protein kinase PHO85", "gene_name": "PHO85", "gene_names_uniprotkb": "PHO85; P7102.18A; SSG3", "gene_names_refseq": "LDB15; PHO85", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17157", "url": "https://www.uniprot.org/uniprotkb/P17157" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17157", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17157" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "GLY_001160", "url": "https://data.glygen.org/GLY_001160", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "S000005952", "url": "https://www.yeastgenome.org/locus/S000005952", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17157", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17157", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "NKTTGVYVALKEVKLDSEEG", "down_seq": "PSTAIREISLMKELKHENIV", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr46", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005952", "url": "https://www.yeastgenome.org/locus/S000005952" }, { "database": "iPTMnet", "id": "P17157", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17157" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr46" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "46", "end_pos": "46" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "18", "end_pos": "18" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "82", "end_pos": "82" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "5", "end_pos": "5" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "P17157-1.36.36", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P17157-1.48.48", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P17157-1.53.53", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17157-1.18.18", "start_pos": 18, "end_pos": 18, "uniprot_canonical_ac": "P17157-1", "length": 305, "uniprot_id": "PHO85_YEAST", "protein_name": "Cyclin-dependent protein kinase PHO85", "refseq_ac": "NP_015294", "refseq_name": "cyclin-dependent serine/threonine-protein kinase PHO85", "gene_name": "PHO85", "gene_names_uniprotkb": "PHO85; P7102.18A; SSG3", "gene_names_refseq": "LDB15; PHO85", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17157", "url": "https://www.uniprot.org/uniprotkb/P17157" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "The Pho85 kinase, a member of the yeast cyclin-dependent kinase (Cdk) family, has a regulation mechanism different from Cdks functioning throughout the cell cycle.", "journal": "Genes to cells : devoted to molecular & cellular mechanisms", "date": "1999-11", "authors": "Nishizawa M, Suzuki K, Fujino M, Oguchi T, Toh-e A", "evidence": [ { "database": "UniProtKB", "id": "P17157", "url": "https://www.uniprot.org/uniprotkb/P17157" }, { "database": "iPTMnet", "id": "P17157", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17157" } ], "reference": [ { "type": "PubMed", "id": "10620010", "url": "https://glygen.org/publication/PubMed/10620010" } ] } ], "crossref": [ { "id": "P17157", "url": "https://www.uniprot.org/uniprotkb/P17157", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10620010", "url": "https://glygen.org/publication/PubMed/10620010", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P17157", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17157", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "MSSSSQFKQLEKLGNGT", "down_seq": "ATVYKGLNKTTGVYVALKEV", "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "F", "comment": "Reduces kinase activity. Abolishes interaction to PHO80 cyclin, but not to PCL1.", "evidence": [ { "database": "UniProtKB", "id": "P17157", "url": "https://www.uniprot.org/uniprotkb/P17157" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "P17157", "url": "https://www.uniprot.org/uniprotkb/P17157" }, { "database": "PubMed", "id": "10620010", "url": "https://glygen.org/publication/PubMed/10620010" }, { "database": "iPTMnet", "id": "P17157", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17157" } ], "site_lbl": "Tyr18" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "46", "end_pos": "46" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "18", "end_pos": "18" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "82", "end_pos": "82" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "5", "end_pos": "5" } ] } ], "categories": [ "mutagenesis_flag", "phosphorylation_flag" ], "glycosylation": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P17157-1.3.3", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P17157-1.4.4", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P17157-1.5.5", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P17157-1.20.20", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P17157-1.36.36", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17157-1.36.36", "start_pos": 36, "end_pos": 36, "uniprot_canonical_ac": "P17157-1", "length": 305, "uniprot_id": "PHO85_YEAST", "protein_name": "Cyclin-dependent protein kinase PHO85", "refseq_ac": "NP_015294", "refseq_name": "cyclin-dependent serine/threonine-protein kinase PHO85", "gene_name": "PHO85", "gene_names_uniprotkb": "PHO85; P7102.18A; SSG3", "gene_names_refseq": "LDB15; PHO85", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17157", "url": "https://www.uniprot.org/uniprotkb/P17157" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "The yeast Pho80-Pho85 cyclin-CDK complex has multiple substrates.", "journal": "Current genetics", "date": "2004-07", "authors": "Waters Norman C, Knight Janine P, Creasy Caretha L, Bergman Lawrence W", "evidence": [ { "database": "UniProtKB", "id": "P17157", "url": "https://www.uniprot.org/uniprotkb/P17157" } ], "reference": [ { "type": "PubMed", "id": "15057567", "url": "https://glygen.org/publication/PubMed/15057567" } ] } ], "crossref": [ { "id": "P17157", "url": "https://www.uniprot.org/uniprotkb/P17157", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "15057567", "url": "https://glygen.org/publication/PubMed/15057567", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "GTYATVYKGLNKTTGVYVAL", "down_seq": "EVKLDSEEGTPSTAIREISL", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "R", "comment": "Loss of kinase activity.", "evidence": [ { "database": "UniProtKB", "id": "P17157", "url": "https://www.uniprot.org/uniprotkb/P17157" }, { "database": "PubMed", "id": "15057567", "url": "https://glygen.org/publication/PubMed/15057567" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "46", "end_pos": "46" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "18", "end_pos": "18" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "82", "end_pos": "82" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "5", "end_pos": "5" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P17157-1.18.18", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P17157-1.20.20", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P17157-1.46.46", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P17157-1.48.48", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P17157-1.53.53", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17157-1.53.53", "start_pos": 53, "end_pos": 53, "uniprot_canonical_ac": "P17157-1", "length": 305, "uniprot_id": "PHO85_YEAST", "protein_name": "Cyclin-dependent protein kinase PHO85", "refseq_ac": "NP_015294", "refseq_name": "cyclin-dependent serine/threonine-protein kinase PHO85", "gene_name": "PHO85", "gene_names_uniprotkb": "PHO85; P7102.18A; SSG3", "gene_names_refseq": "LDB15; PHO85", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17157", "url": "https://www.uniprot.org/uniprotkb/P17157" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "The Pho85 kinase, a member of the yeast cyclin-dependent kinase (Cdk) family, has a regulation mechanism different from Cdks functioning throughout the cell cycle.", "journal": "Genes to cells : devoted to molecular & cellular mechanisms", "date": "1999-11", "authors": "Nishizawa M, Suzuki K, Fujino M, Oguchi T, Toh-e A", "evidence": [ { "database": "UniProtKB", "id": "P17157", "url": "https://www.uniprot.org/uniprotkb/P17157" }, { "database": "iPTMnet", "id": "P17157", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17157" } ], "reference": [ { "type": "PubMed", "id": "10620010", "url": "https://glygen.org/publication/PubMed/10620010" } ] } ], "crossref": [ { "id": "P17157", "url": "https://www.uniprot.org/uniprotkb/P17157", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10620010", "url": "https://glygen.org/publication/PubMed/10620010", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "E", "start_aa": "E", "up_seq": "VALKEVKLDSEEGTPSTAIR", "down_seq": "ISLMKELKHENIVRLYDVIH", "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Loss of kinase activity. Abolishes interaction to PHO80 and PCL1 cyclins.", "evidence": [ { "database": "UniProtKB", "id": "P17157", "url": "https://www.uniprot.org/uniprotkb/P17157" }, { "database": "PubMed", "id": "10620010", "url": "https://glygen.org/publication/PubMed/10620010" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "46", "end_pos": "46" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "18", "end_pos": "18" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "82", "end_pos": "82" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "5", "end_pos": "5" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P17157-1.36.36", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P17157-1.46.46", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P17157-1.48.48", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17157-1.82.82", "start_pos": 82, "end_pos": 82, "uniprot_canonical_ac": "P17157-1", "length": 305, "uniprot_id": "PHO85_YEAST", "protein_name": "Cyclin-dependent protein kinase PHO85", "refseq_ac": "NP_015294", "refseq_name": "cyclin-dependent serine/threonine-protein kinase PHO85", "gene_name": "PHO85", "gene_names_uniprotkb": "PHO85; P7102.18A; SSG3", "gene_names_refseq": "LDB15; PHO85", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17157", "url": "https://www.uniprot.org/uniprotkb/P17157" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Chemical inhibition of the Pho85 cyclin-dependent kinase reveals a role in the environmental stress response.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2001-10-23", "authors": "Carroll A S, Bishop A C, DeRisi J L, Shokat K M, O'Shea E K", "evidence": [ { "database": "UniProtKB", "id": "P17157", "url": "https://www.uniprot.org/uniprotkb/P17157" } ], "reference": [ { "type": "PubMed", "id": "11675494", "url": "https://glygen.org/publication/PubMed/11675494" } ] } ], "crossref": [ { "id": "P17157", "url": "https://www.uniprot.org/uniprotkb/P17157", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "11675494", "url": "https://glygen.org/publication/PubMed/11675494", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "F", "start_aa": "F", "up_seq": "HENIVRLYDVIHTENKLTLV", "down_seq": "EFMDNDLKKYMDSRTVGNTP", "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "G", "comment": "Functional kinase, that can be rapidly inhibited by small, cell-permeable drugs like 1-Na PP1 (4-amino-1-tert-butyl-3-(1'-naphthyl)pyrazolo[3,4-d]pyrimidine).", "evidence": [ { "database": "UniProtKB", "id": "P17157", "url": "https://www.uniprot.org/uniprotkb/P17157" }, { "database": "PubMed", "id": "11675494", "url": "https://glygen.org/publication/PubMed/11675494" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "46", "end_pos": "46" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "18", "end_pos": "18" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "82", "end_pos": "82" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "5", "end_pos": "5" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "upstream", "id": "P17157-1.101.101", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17157-1.101.101", "start_pos": 101, "end_pos": 101, "uniprot_canonical_ac": "P17157-1", "length": 305, "uniprot_id": "PHO85_YEAST", "protein_name": "Cyclin-dependent protein kinase PHO85", "refseq_ac": "NP_015294", "refseq_name": "cyclin-dependent serine/threonine-protein kinase PHO85", "gene_name": "PHO85", "gene_names_uniprotkb": "PHO85; P7102.18A; SSG3", "gene_names_refseq": "LDB15; PHO85", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17157", "url": "https://www.uniprot.org/uniprotkb/P17157" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17157", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17157" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005952", "url": "https://www.yeastgenome.org/locus/S000005952", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17157", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17157", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "VFEFMDNDLKKYMDSRTVGN", "down_seq": "PRGLELNLVKYFQWQLLQGL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005952", "url": "https://www.yeastgenome.org/locus/S000005952" }, { "database": "iPTMnet", "id": "P17157", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17157" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr101" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "46", "end_pos": "46" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "18", "end_pos": "18" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "82", "end_pos": "82" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "5", "end_pos": "5" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P17157-1.82.82", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17157-1.20.20", "start_pos": 20, "end_pos": 20, "uniprot_canonical_ac": "P17157-1", "length": 305, "uniprot_id": "PHO85_YEAST", "protein_name": "Cyclin-dependent protein kinase PHO85", "refseq_ac": "NP_015294", "refseq_name": "cyclin-dependent serine/threonine-protein kinase PHO85", "gene_name": "PHO85", "gene_names_uniprotkb": "PHO85; P7102.18A; SSG3", "gene_names_refseq": "LDB15; PHO85", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17157", "url": "https://www.uniprot.org/uniprotkb/P17157" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17157", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17157" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005952", "url": "https://www.yeastgenome.org/locus/S000005952", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17157", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17157", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "", "down_seq": "VYKGLNKTTGVYVALKEVKL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005952", "url": "https://www.yeastgenome.org/locus/S000005952" }, { "database": "iPTMnet", "id": "P17157", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17157" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr20" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "46", "end_pos": "46" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "18", "end_pos": "18" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "82", "end_pos": "82" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "5", "end_pos": "5" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P17157-1.3.3", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P17157-1.4.4", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P17157-1.5.5", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P17157-1.18.18", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P17157-1.36.36", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17157-1.3.3", "start_pos": 3, "end_pos": 3, "uniprot_canonical_ac": "P17157-1", "length": 305, "uniprot_id": "PHO85_YEAST", "protein_name": "Cyclin-dependent protein kinase PHO85", "refseq_ac": "NP_015294", "refseq_name": "cyclin-dependent serine/threonine-protein kinase PHO85", "gene_name": "PHO85", "gene_names_uniprotkb": "PHO85; P7102.18A; SSG3", "gene_names_refseq": "LDB15; PHO85", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17157", "url": "https://www.uniprot.org/uniprotkb/P17157" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17157", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17157" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005952", "url": "https://www.yeastgenome.org/locus/S000005952", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17157", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17157", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MS", "down_seq": "SSQFKQLEKLGNGTYATVYK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005952", "url": "https://www.yeastgenome.org/locus/S000005952" }, { "database": "iPTMnet", "id": "P17157", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17157" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser3" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "46", "end_pos": "46" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "18", "end_pos": "18" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "82", "end_pos": "82" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "5", "end_pos": "5" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "P17157-1.4.4", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P17157-1.5.5", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P17157-1.18.18", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P17157-1.20.20", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17157-1.48.48", "start_pos": 48, "end_pos": 48, "uniprot_canonical_ac": "P17157-1", "length": 305, "uniprot_id": "PHO85_YEAST", "protein_name": "Cyclin-dependent protein kinase PHO85", "refseq_ac": "NP_015294", "refseq_name": "cyclin-dependent serine/threonine-protein kinase PHO85", "gene_name": "PHO85", "gene_names_uniprotkb": "PHO85; P7102.18A; SSG3", "gene_names_refseq": "LDB15; PHO85", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17157", "url": "https://www.uniprot.org/uniprotkb/P17157" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17157", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17157" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005952", "url": "https://www.yeastgenome.org/locus/S000005952", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17157", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17157", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TTGVYVALKEVKLDSEEGTP", "down_seq": "TAIREISLMKELKHENIVRL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005952", "url": "https://www.yeastgenome.org/locus/S000005952" }, { "database": "iPTMnet", "id": "P17157", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17157" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser48" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "46", "end_pos": "46" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "18", "end_pos": "18" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "82", "end_pos": "82" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "5", "end_pos": "5" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P17157-1.36.36", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P17157-1.46.46", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P17157-1.53.53", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17157-1.4.4", "start_pos": 4, "end_pos": 4, "uniprot_canonical_ac": "P17157-1", "length": 305, "uniprot_id": "PHO85_YEAST", "protein_name": "Cyclin-dependent protein kinase PHO85", "refseq_ac": "NP_015294", "refseq_name": "cyclin-dependent serine/threonine-protein kinase PHO85", "gene_name": "PHO85", "gene_names_uniprotkb": "PHO85; P7102.18A; SSG3", "gene_names_refseq": "LDB15; PHO85", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17157", "url": "https://www.uniprot.org/uniprotkb/P17157" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17157", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17157" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005952", "url": "https://www.yeastgenome.org/locus/S000005952", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17157", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17157", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MSS", "down_seq": "SQFKQLEKLGNGTYATVYKG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005952", "url": "https://www.yeastgenome.org/locus/S000005952" }, { "database": "iPTMnet", "id": "P17157", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17157" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser4" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "46", "end_pos": "46" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "18", "end_pos": "18" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "82", "end_pos": "82" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "5", "end_pos": "5" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "P17157-1.3.3", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P17157-1.5.5", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P17157-1.18.18", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P17157-1.20.20", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17157-1.5.5", "start_pos": 5, "end_pos": 5, "uniprot_canonical_ac": "P17157-1", "length": 305, "uniprot_id": "PHO85_YEAST", "protein_name": "Cyclin-dependent protein kinase PHO85", "refseq_ac": "NP_015294", "refseq_name": "cyclin-dependent serine/threonine-protein kinase PHO85", "gene_name": "PHO85", "gene_names_uniprotkb": "PHO85; P7102.18A; SSG3", "gene_names_refseq": "LDB15; PHO85", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17157", "url": "https://www.uniprot.org/uniprotkb/P17157" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17157", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17157" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005952", "url": "https://www.yeastgenome.org/locus/S000005952", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17157", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17157", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MSSS", "down_seq": "QFKQLEKLGNGTYATVYKGL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005952", "url": "https://www.yeastgenome.org/locus/S000005952" }, { "database": "iPTMnet", "id": "P17157", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17157" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser5" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "46", "end_pos": "46" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "18", "end_pos": "18" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "82", "end_pos": "82" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "5", "end_pos": "5" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P17157-1.3.3", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P17157-1.4.4", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P17157-1.18.18", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P17157-1.20.20", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17505-1.177.177", "start_pos": 177, "end_pos": 177, "uniprot_canonical_ac": "P17505-1", "length": 334, "uniprot_id": "MDHM_YEAST", "protein_name": "Malate dehydrogenase, mitochondrial", "refseq_ac": "NP_012838", "refseq_name": "malate dehydrogenase MDH1", "gene_name": "MDH1", "gene_names_uniprotkb": "MDH1", "gene_names_refseq": "MDH1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17505", "url": "https://www.uniprot.org/uniprotkb/P17505" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase.", "journal": "Molecular & cellular proteomics : MCP", "date": "2007-11", "authors": "Reinders J\u00f6rg, Wagner Karina, Zahedi Rene P, Stojanovski Diana, Eyrich Beate, van der Laan Martin, Rehling Peter, Sickmann Albert, Pfanner Nikolaus, Meisinger Chris", "evidence": [ { "database": "UniProtKB", "id": "P17505", "url": "https://www.uniprot.org/uniprotkb/P17505" }, { "database": "iPTMnet", "id": "P17505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17505" } ], "reference": [ { "type": "PubMed", "id": "17761666", "url": "https://glygen.org/publication/PubMed/17761666" } ] } ], "crossref": [ { "id": "P17505", "url": "https://www.uniprot.org/uniprotkb/P17505", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17761666", "url": "https://glygen.org/publication/PubMed/17761666", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P17505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17505", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000001568", "url": "https://www.yeastgenome.org/locus/S000001568", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NPKKLFGVTTLDSIRAARFI", "down_seq": "EVENTDPTQERVNVIGGHSG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P17505", "url": "https://www.uniprot.org/uniprotkb/P17505" }, { "database": "PubMed", "id": "17761666", "url": "https://glygen.org/publication/PubMed/17761666" }, { "database": "iPTMnet", "id": "P17505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17505" }, { "database": "SGD", "id": "S000001568", "url": "https://www.yeastgenome.org/locus/S000001568" } ], "site_lbl": "Ser177" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "177", "end_pos": "177" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "59", "end_pos": "59" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "upstream", "id": "P17505-1.196.196", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17505-1.196.196", "start_pos": 196, "end_pos": 196, "uniprot_canonical_ac": "P17505-1", "length": 334, "uniprot_id": "MDHM_YEAST", "protein_name": "Malate dehydrogenase, mitochondrial", "refseq_ac": "NP_012838", "refseq_name": "malate dehydrogenase MDH1", "gene_name": "MDH1", "gene_names_uniprotkb": "MDH1", "gene_names_refseq": "MDH1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17505", "url": "https://www.uniprot.org/uniprotkb/P17505" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P17505", "url": "https://www.uniprot.org/uniprotkb/P17505" }, { "database": "iPTMnet", "id": "P17505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17505" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17505" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P17505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17505", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000001568", "url": "https://www.yeastgenome.org/locus/S000001568", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ISEVENTDPTQERVNVIGGH", "down_seq": "GITIIPLISQTNHKLMSDDK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P17505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17505" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001568", "url": "https://www.yeastgenome.org/locus/S000001568" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser196" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "177", "end_pos": "177" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "59", "end_pos": "59" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P17505-1.177.177", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P17505-1.199.199", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P17505-1.213.213", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17505-1.199.199", "start_pos": 199, "end_pos": 199, "uniprot_canonical_ac": "P17505-1", "length": 334, "uniprot_id": "MDHM_YEAST", "protein_name": "Malate dehydrogenase, mitochondrial", "refseq_ac": "NP_012838", "refseq_name": "malate dehydrogenase MDH1", "gene_name": "MDH1", "gene_names_uniprotkb": "MDH1", "gene_names_refseq": "MDH1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17505", "url": "https://www.uniprot.org/uniprotkb/P17505" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P17505", "url": "https://www.uniprot.org/uniprotkb/P17505" }, { "database": "iPTMnet", "id": "P17505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17505" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] } ], "crossref": [ { "id": "P17505", "url": "https://www.uniprot.org/uniprotkb/P17505", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P17505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17505", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000001568", "url": "https://www.yeastgenome.org/locus/S000001568", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "VENTDPTQERVNVIGGHSGI", "down_seq": "IIPLISQTNHKLMSDDKRHE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P17505", "url": "https://www.uniprot.org/uniprotkb/P17505" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P17505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17505" }, { "database": "SGD", "id": "S000001568", "url": "https://www.yeastgenome.org/locus/S000001568" } ], "site_lbl": "Thr199" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "177", "end_pos": "177" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "59", "end_pos": "59" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P17505-1.196.196", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P17505-1.213.213", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17505-1.213.213", "start_pos": 213, "end_pos": 213, "uniprot_canonical_ac": "P17505-1", "length": 334, "uniprot_id": "MDHM_YEAST", "protein_name": "Malate dehydrogenase, mitochondrial", "refseq_ac": "NP_012838", "refseq_name": "malate dehydrogenase MDH1", "gene_name": "MDH1", "gene_names_uniprotkb": "MDH1", "gene_names_refseq": "MDH1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17505", "url": "https://www.uniprot.org/uniprotkb/P17505" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17505" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000001568", "url": "https://www.yeastgenome.org/locus/S000001568", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17505", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GGHSGITIIPLISQTNHKLM", "down_seq": "DDKRHELIHRIQFGGDEVVK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000001568", "url": "https://www.yeastgenome.org/locus/S000001568" }, { "database": "iPTMnet", "id": "P17505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17505" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser213" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "177", "end_pos": "177" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "59", "end_pos": "59" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P17505-1.196.196", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P17505-1.199.199", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17505-1.240.240", "start_pos": 240, "end_pos": 240, "uniprot_canonical_ac": "P17505-1", "length": 334, "uniprot_id": "MDHM_YEAST", "protein_name": "Malate dehydrogenase, mitochondrial", "refseq_ac": "NP_012838", "refseq_name": "malate dehydrogenase MDH1", "gene_name": "MDH1", "gene_names_uniprotkb": "MDH1", "gene_names_refseq": "MDH1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17505", "url": "https://www.uniprot.org/uniprotkb/P17505" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P17505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17505" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17505" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000001568", "url": "https://www.yeastgenome.org/locus/S000001568", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17505", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LIHRIQFGGDEVVKAKNGAG", "down_seq": "ATLSMAHAGAKFANAVLSGF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000001568", "url": "https://www.yeastgenome.org/locus/S000001568" }, { "database": "iPTMnet", "id": "P17505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17505" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser240" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "177", "end_pos": "177" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "59", "end_pos": "59" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "P17505-1.244.244", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P17505-1.258.258", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17505-1.244.244", "start_pos": 244, "end_pos": 244, "uniprot_canonical_ac": "P17505-1", "length": 334, "uniprot_id": "MDHM_YEAST", "protein_name": "Malate dehydrogenase, mitochondrial", "refseq_ac": "NP_012838", "refseq_name": "malate dehydrogenase MDH1", "gene_name": "MDH1", "gene_names_uniprotkb": "MDH1", "gene_names_refseq": "MDH1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17505", "url": "https://www.uniprot.org/uniprotkb/P17505" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17505" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000001568", "url": "https://www.yeastgenome.org/locus/S000001568", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17505", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IQFGGDEVVKAKNGAGSATL", "down_seq": "MAHAGAKFANAVLSGFKGER", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000001568", "url": "https://www.yeastgenome.org/locus/S000001568" }, { "database": "iPTMnet", "id": "P17505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17505" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser244" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "177", "end_pos": "177" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "59", "end_pos": "59" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P17505-1.240.240", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P17505-1.258.258", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17505-1.258.258", "start_pos": 258, "end_pos": 258, "uniprot_canonical_ac": "P17505-1", "length": 334, "uniprot_id": "MDHM_YEAST", "protein_name": "Malate dehydrogenase, mitochondrial", "refseq_ac": "NP_012838", "refseq_name": "malate dehydrogenase MDH1", "gene_name": "MDH1", "gene_names_uniprotkb": "MDH1", "gene_names_refseq": "MDH1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17505", "url": "https://www.uniprot.org/uniprotkb/P17505" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17505" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000001568", "url": "https://www.yeastgenome.org/locus/S000001568", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17505", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AGSATLSMAHAGAKFANAVL", "down_seq": "GFKGERDVIEPSFVDSPLFK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000001568", "url": "https://www.yeastgenome.org/locus/S000001568" }, { "database": "iPTMnet", "id": "P17505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17505" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser258" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "177", "end_pos": "177" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "59", "end_pos": "59" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P17505-1.240.240", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P17505-1.244.244", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17505-1.306.306", "start_pos": 306, "end_pos": 306, "uniprot_canonical_ac": "P17505-1", "length": 334, "uniprot_id": "MDHM_YEAST", "protein_name": "Malate dehydrogenase, mitochondrial", "refseq_ac": "NP_012838", "refseq_name": "malate dehydrogenase MDH1", "gene_name": "MDH1", "gene_names_uniprotkb": "MDH1", "gene_names_refseq": "MDH1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17505", "url": "https://www.uniprot.org/uniprotkb/P17505" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17505" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000001568", "url": "https://www.yeastgenome.org/locus/S000001568", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17505", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ASPVTLGPDGIEKIHPIGEL", "down_seq": "SEEEEMLQKCKETLKKNIEK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000001568", "url": "https://www.yeastgenome.org/locus/S000001568" }, { "database": "iPTMnet", "id": "P17505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17505" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser306" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "177", "end_pos": "177" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "59", "end_pos": "59" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17505-1.59.59", "start_pos": 59, "end_pos": 59, "uniprot_canonical_ac": "P17505-1", "length": 334, "uniprot_id": "MDHM_YEAST", "protein_name": "Malate dehydrogenase, mitochondrial", "refseq_ac": "NP_012838", "refseq_name": "malate dehydrogenase MDH1", "gene_name": "MDH1", "gene_names_uniprotkb": "MDH1", "gene_names_refseq": "MDH1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17505", "url": "https://www.uniprot.org/uniprotkb/P17505" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P17505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17505" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "crossref": [ { "id": "S000001568", "url": "https://www.yeastgenome.org/locus/S000001568", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17505", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "LNHKVTDLRLYDLKGAKGVA", "down_seq": "DLSHIPTNSVVKGFTPEEPD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000001568", "url": "https://www.yeastgenome.org/locus/S000001568" }, { "database": "iPTMnet", "id": "P17505", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17505" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Thr59" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "177", "end_pos": "177" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "199", "end_pos": "199" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "59", "end_pos": "59" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17555-1.116.116", "start_pos": 116, "end_pos": 116, "uniprot_canonical_ac": "P17555-1", "length": 526, "uniprot_id": "CAP_YEAST", "protein_name": "Adenylyl cyclase-associated protein", "refseq_ac": "NP_014261", "refseq_name": "adenylate cyclase-binding protein", "gene_name": "SRV2", "gene_names_uniprotkb": "SRV2; CAP1; N1210; N1838", "gene_names_refseq": "CAP; SRV2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17555", "url": "https://www.uniprot.org/uniprotkb/P17555" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SGKIDTVVLDALQLLKGGFQ", "down_seq": "QLTFLRAAVRSRKPDYSSQT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082" }, { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser116" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "342", "end_pos": "342" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "463", "end_pos": "463" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "6", "end_pos": "6" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17555-1.161.161", "start_pos": 161, "end_pos": 161, "uniprot_canonical_ac": "P17555-1", "length": 526, "uniprot_id": "CAP_YEAST", "protein_name": "Adenylyl cyclase-associated protein", "refseq_ac": "NP_014261", "refseq_name": "adenylate cyclase-binding protein", "gene_name": "SRV2", "gene_names_uniprotkb": "SRV2; CAP1; N1210; N1838", "gene_names_refseq": "CAP; SRV2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17555", "url": "https://www.uniprot.org/uniprotkb/P17555" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LRPINENIIKLGQLKESNRQ", "down_seq": "KYFAYLSALSEGAPLFSWVA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082" }, { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser161" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "342", "end_pos": "342" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "463", "end_pos": "463" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "6", "end_pos": "6" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17555-1.292.292", "start_pos": 292, "end_pos": 292, "uniprot_canonical_ac": "P17555-1", "length": 526, "uniprot_id": "CAP_YEAST", "protein_name": "Adenylyl cyclase-associated protein", "refseq_ac": "NP_014261", "refseq_name": "adenylate cyclase-binding protein", "gene_name": "SRV2", "gene_names_uniprotkb": "SRV2; CAP1; N1210; N1838", "gene_names_refseq": "CAP; SRV2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17555", "url": "https://www.uniprot.org/uniprotkb/P17555" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TAAPAPPPPPPAPPASVFEI", "down_seq": "NDTPATSSDANKGGIGAVFA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082" }, { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser292" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "342", "end_pos": "342" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "463", "end_pos": "463" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "6", "end_pos": "6" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "P17555-1.295.295", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17555-1.295.295", "start_pos": 295, "end_pos": 295, "uniprot_canonical_ac": "P17555-1", "length": 526, "uniprot_id": "CAP_YEAST", "protein_name": "Adenylyl cyclase-associated protein", "refseq_ac": "NP_014261", "refseq_name": "adenylate cyclase-binding protein", "gene_name": "SRV2", "gene_names_uniprotkb": "SRV2; CAP1; N1210; N1838", "gene_names_refseq": "CAP; SRV2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17555", "url": "https://www.uniprot.org/uniprotkb/P17555" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PAPPPPPPAPPASVFEISND", "down_seq": "PATSSDANKGGIGAVFAELN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082" }, { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr295" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "342", "end_pos": "342" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "463", "end_pos": "463" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "6", "end_pos": "6" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P17555-1.292.292", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17555-1.342.342", "start_pos": 342, "end_pos": 342, "uniprot_canonical_ac": "P17555-1", "length": 526, "uniprot_id": "CAP_YEAST", "protein_name": "Adenylyl cyclase-associated protein", "refseq_ac": "NP_014261", "refseq_name": "adenylate cyclase-binding protein", "gene_name": "SRV2", "gene_names_uniprotkb": "SRV2; CAP1; N1210; N1838", "gene_names_refseq": "CAP; SRV2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17555", "url": "https://www.uniprot.org/uniprotkb/P17555" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KGLKKVDKSQQTHKNPELRQ", "down_seq": "STVSSTGSKSGPPPRPKKPS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser342" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "342", "end_pos": "342" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "463", "end_pos": "463" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "6", "end_pos": "6" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "P17555-1.343.343", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P17555-1.346.346", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P17555-1.347.347", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P17555-1.350.350", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P17555-1.352.352", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P17555-1.362.362", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17555-1.343.343", "start_pos": 343, "end_pos": 343, "uniprot_canonical_ac": "P17555-1", "length": 526, "uniprot_id": "CAP_YEAST", "protein_name": "Adenylyl cyclase-associated protein", "refseq_ac": "NP_014261", "refseq_name": "adenylate cyclase-binding protein", "gene_name": "SRV2", "gene_names_uniprotkb": "SRV2; CAP1; N1210; N1838", "gene_names_refseq": "CAP; SRV2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17555", "url": "https://www.uniprot.org/uniprotkb/P17555" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "The Yeast DNA Damage Checkpoint Kinase Rad53 Targets the Exoribonuclease, Xrn1.", "journal": "G3 (Bethesda, Md.)", "date": "2018-12-10", "authors": "Lao Jessica P, Ulrich Katie M, Johnson Jeffrey R, Newton Billy W, Vashisht Ajay A, Wohlschlegel James A, Krogan Nevan J, Toczyski David P", "evidence": [ { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" } ], "reference": [ { "type": "PubMed", "id": "30377154", "url": "https://glygen.org/publication/PubMed/30377154" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "30377154", "url": "https://glygen.org/publication/PubMed/30377154", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GLKKVDKSQQTHKNPELRQS", "down_seq": "TVSSTGSKSGPPPRPKKPST", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082" }, { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" }, { "database": "PubMed", "id": "30377154", "url": "https://glygen.org/publication/PubMed/30377154" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser343" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "342", "end_pos": "342" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "463", "end_pos": "463" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "6", "end_pos": "6" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "P17555-1.342.342", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P17555-1.346.346", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P17555-1.347.347", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P17555-1.350.350", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P17555-1.352.352", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P17555-1.362.362", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17555-1.346.346", "start_pos": 346, "end_pos": 346, "uniprot_canonical_ac": "P17555-1", "length": 526, "uniprot_id": "CAP_YEAST", "protein_name": "Adenylyl cyclase-associated protein", "refseq_ac": "NP_014261", "refseq_name": "adenylate cyclase-binding protein", "gene_name": "SRV2", "gene_names_uniprotkb": "SRV2; CAP1; N1210; N1838", "gene_names_refseq": "CAP; SRV2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17555", "url": "https://www.uniprot.org/uniprotkb/P17555" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "The Yeast DNA Damage Checkpoint Kinase Rad53 Targets the Exoribonuclease, Xrn1.", "journal": "G3 (Bethesda, Md.)", "date": "2018-12-10", "authors": "Lao Jessica P, Ulrich Katie M, Johnson Jeffrey R, Newton Billy W, Vashisht Ajay A, Wohlschlegel James A, Krogan Nevan J, Toczyski David P", "evidence": [ { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" } ], "reference": [ { "type": "PubMed", "id": "30377154", "url": "https://glygen.org/publication/PubMed/30377154" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "30377154", "url": "https://glygen.org/publication/PubMed/30377154", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KVDKSQQTHKNPELRQSSTV", "down_seq": "STGSKSGPPPRPKKPSTLKT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082" }, { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" }, { "database": "PubMed", "id": "30377154", "url": "https://glygen.org/publication/PubMed/30377154" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser346" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "342", "end_pos": "342" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "463", "end_pos": "463" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "6", "end_pos": "6" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P17555-1.342.342", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P17555-1.343.343", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P17555-1.347.347", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P17555-1.350.350", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P17555-1.352.352", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P17555-1.362.362", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17555-1.347.347", "start_pos": 347, "end_pos": 347, "uniprot_canonical_ac": "P17555-1", "length": 526, "uniprot_id": "CAP_YEAST", "protein_name": "Adenylyl cyclase-associated protein", "refseq_ac": "NP_014261", "refseq_name": "adenylate cyclase-binding protein", "gene_name": "SRV2", "gene_names_uniprotkb": "SRV2; CAP1; N1210; N1838", "gene_names_refseq": "CAP; SRV2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17555", "url": "https://www.uniprot.org/uniprotkb/P17555" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ], "crossref": [ { "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VDKSQQTHKNPELRQSSTVS", "down_seq": "TGSKSGPPPRPKKPSTLKTK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082" }, { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ], "site_lbl": "Ser347" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "342", "end_pos": "342" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "463", "end_pos": "463" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "6", "end_pos": "6" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "P17555-1.342.342", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P17555-1.343.343", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P17555-1.346.346", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P17555-1.350.350", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P17555-1.352.352", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P17555-1.362.362", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17555-1.350.350", "start_pos": 350, "end_pos": 350, "uniprot_canonical_ac": "P17555-1", "length": 526, "uniprot_id": "CAP_YEAST", "protein_name": "Adenylyl cyclase-associated protein", "refseq_ac": "NP_014261", "refseq_name": "adenylate cyclase-binding protein", "gene_name": "SRV2", "gene_names_uniprotkb": "SRV2; CAP1; N1210; N1838", "gene_names_refseq": "CAP; SRV2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17555", "url": "https://www.uniprot.org/uniprotkb/P17555" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SQQTHKNPELRQSSTVSSTG", "down_seq": "KSGPPPRPKKPSTLKTKRPP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082" }, { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser350" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "342", "end_pos": "342" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "463", "end_pos": "463" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "6", "end_pos": "6" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "P17555-1.342.342", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P17555-1.343.343", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P17555-1.346.346", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P17555-1.347.347", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P17555-1.352.352", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P17555-1.362.362", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17555-1.352.352", "start_pos": 352, "end_pos": 352, "uniprot_canonical_ac": "P17555-1", "length": 526, "uniprot_id": "CAP_YEAST", "protein_name": "Adenylyl cyclase-associated protein", "refseq_ac": "NP_014261", "refseq_name": "adenylate cyclase-binding protein", "gene_name": "SRV2", "gene_names_uniprotkb": "SRV2; CAP1; N1210; N1838", "gene_names_refseq": "CAP; SRV2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17555", "url": "https://www.uniprot.org/uniprotkb/P17555" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "crossref": [ { "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QTHKNPELRQSSTVSSTGSK", "down_seq": "GPPPRPKKPSTLKTKRPPRK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082" }, { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Ser352" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "342", "end_pos": "342" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "463", "end_pos": "463" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "6", "end_pos": "6" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "P17555-1.342.342", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P17555-1.343.343", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P17555-1.346.346", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P17555-1.347.347", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P17555-1.350.350", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P17555-1.362.362", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17555-1.362.362", "start_pos": 362, "end_pos": 362, "uniprot_canonical_ac": "P17555-1", "length": 526, "uniprot_id": "CAP_YEAST", "protein_name": "Adenylyl cyclase-associated protein", "refseq_ac": "NP_014261", "refseq_name": "adenylate cyclase-binding protein", "gene_name": "SRV2", "gene_names_uniprotkb": "SRV2; CAP1; N1210; N1838", "gene_names_refseq": "CAP; SRV2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17555", "url": "https://www.uniprot.org/uniprotkb/P17555" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ], "crossref": [ { "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SSTVSSTGSKSGPPPRPKKP", "down_seq": "TLKTKRPPRKELVGNKWFIE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082" }, { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ], "site_lbl": "Ser362" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "342", "end_pos": "342" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "463", "end_pos": "463" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "6", "end_pos": "6" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P17555-1.342.342", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "downstream", "id": "P17555-1.343.343", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P17555-1.346.346", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P17555-1.347.347", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P17555-1.350.350", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P17555-1.352.352", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17555-1.388.388", "start_pos": 388, "end_pos": 388, "uniprot_canonical_ac": "P17555-1", "length": 526, "uniprot_id": "CAP_YEAST", "protein_name": "Adenylyl cyclase-associated protein", "refseq_ac": "NP_014261", "refseq_name": "adenylate cyclase-binding protein", "gene_name": "SRV2", "gene_names_uniprotkb": "SRV2; CAP1; N1210; N1838", "gene_names_refseq": "CAP; SRV2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17555", "url": "https://www.uniprot.org/uniprotkb/P17555" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "RPPRKELVGNKWFIENYENE", "down_seq": "ESLVIDANKDESIFIGKCSQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082" }, { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr388" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "342", "end_pos": "342" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "463", "end_pos": "463" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "6", "end_pos": "6" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17555-1.454.454", "start_pos": 454, "end_pos": 454, "uniprot_canonical_ac": "P17555-1", "length": 526, "uniprot_id": "CAP_YEAST", "protein_name": "Adenylyl cyclase-associated protein", "refseq_ac": "NP_014261", "refseq_name": "adenylate cyclase-binding protein", "gene_name": "SRV2", "gene_names_uniprotkb": "SRV2; CAP1; N1210; N1838", "gene_names_refseq": "CAP; SRV2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17555", "url": "https://www.uniprot.org/uniprotkb/P17555" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P17555", "url": "https://www.uniprot.org/uniprotkb/P17555" }, { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P17555", "url": "https://www.uniprot.org/uniprotkb/P17555", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SSISGMDVIKSNKFGIQVNH", "down_seq": "LPQISIDKSDGGNIYLSKES", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P17555", "url": "https://www.uniprot.org/uniprotkb/P17555" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" }, { "database": "SGD", "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser454" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "342", "end_pos": "342" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "463", "end_pos": "463" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "6", "end_pos": "6" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "upstream", "id": "P17555-1.463.463", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P17555-1.471.471", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17555-1.463.463", "start_pos": 463, "end_pos": 463, "uniprot_canonical_ac": "P17555-1", "length": 526, "uniprot_id": "CAP_YEAST", "protein_name": "Adenylyl cyclase-associated protein", "refseq_ac": "NP_014261", "refseq_name": "adenylate cyclase-binding protein", "gene_name": "SRV2", "gene_names_uniprotkb": "SRV2; CAP1; N1210; N1838", "gene_names_refseq": "CAP; SRV2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17555", "url": "https://www.uniprot.org/uniprotkb/P17555" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KSNKFGIQVNHSLPQISIDK", "down_seq": "DGGNIYLSKESLNTEIYTSC", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082" }, { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser463" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "342", "end_pos": "342" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "463", "end_pos": "463" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "6", "end_pos": "6" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "P17555-1.454.454", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P17555-1.471.471", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17555-1.471.471", "start_pos": 471, "end_pos": 471, "uniprot_canonical_ac": "P17555-1", "length": 526, "uniprot_id": "CAP_YEAST", "protein_name": "Adenylyl cyclase-associated protein", "refseq_ac": "NP_014261", "refseq_name": "adenylate cyclase-binding protein", "gene_name": "SRV2", "gene_names_uniprotkb": "SRV2; CAP1; N1210; N1838", "gene_names_refseq": "CAP; SRV2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17555", "url": "https://www.uniprot.org/uniprotkb/P17555" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VNHSLPQISIDKSDGGNIYL", "down_seq": "KESLNTEIYTSCSTAINVNL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082" }, { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser471" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "342", "end_pos": "342" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "463", "end_pos": "463" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "6", "end_pos": "6" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P17555-1.454.454", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P17555-1.463.463", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17555-1.4.4", "start_pos": 4, "end_pos": 4, "uniprot_canonical_ac": "P17555-1", "length": 526, "uniprot_id": "CAP_YEAST", "protein_name": "Adenylyl cyclase-associated protein", "refseq_ac": "NP_014261", "refseq_name": "adenylate cyclase-binding protein", "gene_name": "SRV2", "gene_names_uniprotkb": "SRV2; CAP1; N1210; N1838", "gene_names_refseq": "CAP; SRV2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17555", "url": "https://www.uniprot.org/uniprotkb/P17555" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MPD", "down_seq": "KYTMQGYNLVKLLKRLEEAT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082" }, { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser4" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "342", "end_pos": "342" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "463", "end_pos": "463" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "6", "end_pos": "6" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P17555-1.6.6", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17555-1.519.519", "start_pos": 519, "end_pos": 519, "uniprot_canonical_ac": "P17555-1", "length": 526, "uniprot_id": "CAP_YEAST", "protein_name": "Adenylyl cyclase-associated protein", "refseq_ac": "NP_014261", "refseq_name": "adenylate cyclase-binding protein", "gene_name": "SRV2", "gene_names_uniprotkb": "SRV2; CAP1; N1210; N1838", "gene_names_refseq": "CAP; SRV2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17555", "url": "https://www.uniprot.org/uniprotkb/P17555" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "YVEFPIPEQMKHSFADGKFK", "down_seq": "AVFEHAG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082" }, { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser519" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "342", "end_pos": "342" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "463", "end_pos": "463" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "6", "end_pos": "6" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17555-1.60.60", "start_pos": 60, "end_pos": 60, "uniprot_canonical_ac": "P17555-1", "length": 526, "uniprot_id": "CAP_YEAST", "protein_name": "Adenylyl cyclase-associated protein", "refseq_ac": "NP_014261", "refseq_name": "adenylate cyclase-binding protein", "gene_name": "SRV2", "gene_names_uniprotkb": "SRV2; CAP1; N1210; N1838", "gene_names_refseq": "CAP; SRV2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17555", "url": "https://www.uniprot.org/uniprotkb/P17555" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "crossref": [ { "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "NKLEASKNNKPSDSGADANT", "down_seq": "NEPSAENAPEVEQDPKCITA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082" }, { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Thr60" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "342", "end_pos": "342" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "463", "end_pos": "463" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "6", "end_pos": "6" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "P17555-1.64.64", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17555-1.64.64", "start_pos": 64, "end_pos": 64, "uniprot_canonical_ac": "P17555-1", "length": 526, "uniprot_id": "CAP_YEAST", "protein_name": "Adenylyl cyclase-associated protein", "refseq_ac": "NP_014261", "refseq_name": "adenylate cyclase-binding protein", "gene_name": "SRV2", "gene_names_uniprotkb": "SRV2; CAP1; N1210; N1838", "gene_names_refseq": "CAP; SRV2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17555", "url": "https://www.uniprot.org/uniprotkb/P17555" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "crossref": [ { "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ASKNNKPSDSGADANTTNEP", "down_seq": "AENAPEVEQDPKCITAFQSY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082" }, { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Ser64" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "342", "end_pos": "342" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "463", "end_pos": "463" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "6", "end_pos": "6" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P17555-1.60.60", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17555-1.6.6", "start_pos": 6, "end_pos": 6, "uniprot_canonical_ac": "P17555-1", "length": 526, "uniprot_id": "CAP_YEAST", "protein_name": "Adenylyl cyclase-associated protein", "refseq_ac": "NP_014261", "refseq_name": "adenylate cyclase-binding protein", "gene_name": "SRV2", "gene_names_uniprotkb": "SRV2; CAP1; N1210; N1838", "gene_names_refseq": "CAP; SRV2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P17555", "url": "https://www.uniprot.org/uniprotkb/P17555" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "MPDSK", "down_seq": "TMQGYNLVKLLKRLEEATAR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005082", "url": "https://www.yeastgenome.org/locus/S000005082" }, { "database": "iPTMnet", "id": "P17555", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17555" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Tyr6" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "342", "end_pos": "342" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "388", "end_pos": "388" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "463", "end_pos": "463" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "6", "end_pos": "6" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P17555-1.4.4", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P18239-1.109.109", "start_pos": 109, "end_pos": 109, "uniprot_canonical_ac": "P18239-1", "length": 318, "uniprot_id": "ADT2_YEAST", "protein_name": "ADP/ATP translocase 2", "refseq_ac": "NP_009523", "refseq_name": "ADP/ATP carrier protein PET9", "gene_name": "PET9", "gene_names_uniprotkb": "PET9; AAC2; YBL0421", "gene_names_refseq": "AAC2; ANC2; PET9", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Structures of yeast mitochondrial ADP/ATP carriers support a domain-based alternating-access transport mechanism.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2014-01-28", "authors": "Ruprecht Jonathan J, Hellawell Alex M, Harding Marilyn, Crichton Paul G, McCoy Airlie J, Kunji Edmund R S", "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" } ], "reference": [ { "type": "PubMed", "id": "24474793", "url": "https://glygen.org/publication/PubMed/24474793" } ] } ], "crossref": [ { "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "24474793", "url": "https://glygen.org/publication/PubMed/24474793", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "GNTANVIRYFPTQALNFAFK", "down_seq": "KIKAMFGFKKEEGYAKWFAG", "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "K", "comment": "Loss of transport activity; when associated with K-212 and K-306. Restored transport activity; when associated with D-112; K-212; D-215; K-306 and D-309.", "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" }, { "database": "PubMed", "id": "24474793", "url": "https://glygen.org/publication/PubMed/24474793" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "109", "end_pos": "109" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "73", "end_pos": "73" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "183", "end_pos": "183" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "P18239-1.112.112", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P18239-1.112.112", "start_pos": 112, "end_pos": 112, "uniprot_canonical_ac": "P18239-1", "length": 318, "uniprot_id": "ADT2_YEAST", "protein_name": "ADP/ATP translocase 2", "refseq_ac": "NP_009523", "refseq_name": "ADP/ATP carrier protein PET9", "gene_name": "PET9", "gene_names_uniprotkb": "PET9; AAC2; YBL0421", "gene_names_refseq": "AAC2; ANC2; PET9", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Structures of yeast mitochondrial ADP/ATP carriers support a domain-based alternating-access transport mechanism.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2014-01-28", "authors": "Ruprecht Jonathan J, Hellawell Alex M, Harding Marilyn, Crichton Paul G, McCoy Airlie J, Kunji Edmund R S", "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" } ], "reference": [ { "type": "PubMed", "id": "24474793", "url": "https://glygen.org/publication/PubMed/24474793" } ] } ], "crossref": [ { "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "24474793", "url": "https://glygen.org/publication/PubMed/24474793", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "ANVIRYFPTQALNFAFKDKI", "down_seq": "AMFGFKKEEGYAKWFAGNLA", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "D", "comment": "Loss of transport activity; when associated with D-215 and D-309. Restored transport activity; when associated with K-109; K-212; D-215; K-306 and D-309.", "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" }, { "database": "PubMed", "id": "24474793", "url": "https://glygen.org/publication/PubMed/24474793" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "109", "end_pos": "109" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "73", "end_pos": "73" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "183", "end_pos": "183" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P18239-1.109.109", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P18239-1.212.212", "start_pos": 212, "end_pos": 212, "uniprot_canonical_ac": "P18239-1", "length": 318, "uniprot_id": "ADT2_YEAST", "protein_name": "ADP/ATP translocase 2", "refseq_ac": "NP_009523", "refseq_name": "ADP/ATP carrier protein PET9", "gene_name": "PET9", "gene_names_uniprotkb": "PET9; AAC2; YBL0421", "gene_names_refseq": "AAC2; ANC2; PET9", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Structures of yeast mitochondrial ADP/ATP carriers support a domain-based alternating-access transport mechanism.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2014-01-28", "authors": "Ruprecht Jonathan J, Hellawell Alex M, Harding Marilyn, Crichton Paul G, McCoy Airlie J, Kunji Edmund R S", "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" } ], "reference": [ { "type": "PubMed", "id": "24474793", "url": "https://glygen.org/publication/PubMed/24474793" } ] } ], "crossref": [ { "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "24474793", "url": "https://glygen.org/publication/PubMed/24474793", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "GFLPSVVGIVVYRGLYFGMY", "down_seq": "SLKPLLLTGSLEGSFLASFL", "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "K", "comment": "Loss of transport activity; when associated with K-109 and K-306. Restored transport activity; when associated with D-109; D-112; D-215; K-306 and D-309.", "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" }, { "database": "PubMed", "id": "24474793", "url": "https://glygen.org/publication/PubMed/24474793" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "109", "end_pos": "109" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "73", "end_pos": "73" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "183", "end_pos": "183" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "P18239-1.215.215", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P18239-1.215.215", "start_pos": 215, "end_pos": 215, "uniprot_canonical_ac": "P18239-1", "length": 318, "uniprot_id": "ADT2_YEAST", "protein_name": "ADP/ATP translocase 2", "refseq_ac": "NP_009523", "refseq_name": "ADP/ATP carrier protein PET9", "gene_name": "PET9", "gene_names_uniprotkb": "PET9; AAC2; YBL0421", "gene_names_refseq": "AAC2; ANC2; PET9", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Structures of yeast mitochondrial ADP/ATP carriers support a domain-based alternating-access transport mechanism.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2014-01-28", "authors": "Ruprecht Jonathan J, Hellawell Alex M, Harding Marilyn, Crichton Paul G, McCoy Airlie J, Kunji Edmund R S", "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" } ], "reference": [ { "type": "PubMed", "id": "24474793", "url": "https://glygen.org/publication/PubMed/24474793" } ] } ], "crossref": [ { "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "24474793", "url": "https://glygen.org/publication/PubMed/24474793", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "PSVVGIVVYRGLYFGMYDSL", "down_seq": "PLLLTGSLEGSFLASFLLGW", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "D", "comment": "Loss of transport activity; when associated with D-112 and D-309. Restored transport activity; when associated with K-109; D-112; K-212; K-306 and D-309.", "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" }, { "database": "PubMed", "id": "24474793", "url": "https://glygen.org/publication/PubMed/24474793" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "109", "end_pos": "109" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "73", "end_pos": "73" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "183", "end_pos": "183" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P18239-1.212.212", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P18239-1.244.244", "start_pos": 244, "end_pos": 244, "uniprot_canonical_ac": "P18239-1", "length": 318, "uniprot_id": "ADT2_YEAST", "protein_name": "ADP/ATP translocase 2", "refseq_ac": "NP_009523", "refseq_name": "ADP/ATP carrier protein PET9", "gene_name": "PET9", "gene_names_uniprotkb": "PET9; AAC2; YBL0421", "gene_names_refseq": "AAC2; ANC2; PET9", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "The yeast mitochondrial ADP/ATP carrier functions as a monomer in mitochondrial membranes.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-06-26", "authors": "Bamber Lisa, Harding Marilyn, Monn\u00e9 Magnus, Slotboom Dirk-Jan, Kunji Edmund R S", "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" } ], "reference": [ { "type": "PubMed", "id": "17566106", "url": "https://glygen.org/publication/PubMed/17566106" } ] } ], "crossref": [ { "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17566106", "url": "https://glygen.org/publication/PubMed/17566106", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "EGSFLASFLLGWVVTTGAST", "down_seq": "SYPLDTVRRRMMMTSGQAVK", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Loss of inhibition by activity regulator 2-sulfonatoethyl-methanethiosulfonate(MTSES); when associated with A-73; A-271 and A-288.", "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" }, { "database": "PubMed", "id": "17566106", "url": "https://glygen.org/publication/PubMed/17566106" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "109", "end_pos": "109" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "73", "end_pos": "73" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "183", "end_pos": "183" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P18239-1.271.271", "start_pos": 271, "end_pos": 271, "uniprot_canonical_ac": "P18239-1", "length": 318, "uniprot_id": "ADT2_YEAST", "protein_name": "ADP/ATP translocase 2", "refseq_ac": "NP_009523", "refseq_name": "ADP/ATP carrier protein PET9", "gene_name": "PET9", "gene_names_uniprotkb": "PET9; AAC2; YBL0421", "gene_names_refseq": "AAC2; ANC2; PET9", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "The yeast mitochondrial ADP/ATP carrier functions as a monomer in mitochondrial membranes.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-06-26", "authors": "Bamber Lisa, Harding Marilyn, Monn\u00e9 Magnus, Slotboom Dirk-Jan, Kunji Edmund R S", "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" } ], "reference": [ { "type": "PubMed", "id": "17566106", "url": "https://glygen.org/publication/PubMed/17566106" } ] } ], "crossref": [ { "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17566106", "url": "https://glygen.org/publication/PubMed/17566106", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "VRRRMMMTSGQAVKYDGAFD", "down_seq": "LRKIVAAEGVGSLFKGCGAN", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Loss of inhibition by activity regulator 2-sulfonatoethyl-methanethiosulfonate(MTSES); when associated with A-73; A-244 and A-288.", "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" }, { "database": "PubMed", "id": "17566106", "url": "https://glygen.org/publication/PubMed/17566106" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "109", "end_pos": "109" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "73", "end_pos": "73" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "183", "end_pos": "183" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "upstream", "id": "P18239-1.283.283", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P18239-1.288.288", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P18239-1.288.288", "start_pos": 288, "end_pos": 288, "uniprot_canonical_ac": "P18239-1", "length": 318, "uniprot_id": "ADT2_YEAST", "protein_name": "ADP/ATP translocase 2", "refseq_ac": "NP_009523", "refseq_name": "ADP/ATP carrier protein PET9", "gene_name": "PET9", "gene_names_uniprotkb": "PET9; AAC2; YBL0421", "gene_names_refseq": "AAC2; ANC2; PET9", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "The yeast mitochondrial ADP/ATP carrier functions as a monomer in mitochondrial membranes.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-06-26", "authors": "Bamber Lisa, Harding Marilyn, Monn\u00e9 Magnus, Slotboom Dirk-Jan, Kunji Edmund R S", "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" } ], "reference": [ { "type": "PubMed", "id": "17566106", "url": "https://glygen.org/publication/PubMed/17566106" } ] } ], "crossref": [ { "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17566106", "url": "https://glygen.org/publication/PubMed/17566106", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "AFDCLRKIVAAEGVGSLFKG", "down_seq": "GANILRGVAGAGVISMYDQL", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Loss of inhibition by activity regulator 2-sulfonatoethyl-methanethiosulfonate(MTSES); when associated with A-73; A-244 and A-271.", "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" }, { "database": "PubMed", "id": "17566106", "url": "https://glygen.org/publication/PubMed/17566106" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "109", "end_pos": "109" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "73", "end_pos": "73" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "183", "end_pos": "183" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P18239-1.271.271", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P18239-1.283.283", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P18239-1.306.306", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P18239-1.306.306", "start_pos": 306, "end_pos": 306, "uniprot_canonical_ac": "P18239-1", "length": 318, "uniprot_id": "ADT2_YEAST", "protein_name": "ADP/ATP translocase 2", "refseq_ac": "NP_009523", "refseq_name": "ADP/ATP carrier protein PET9", "gene_name": "PET9", "gene_names_uniprotkb": "PET9; AAC2; YBL0421", "gene_names_refseq": "AAC2; ANC2; PET9", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Structures of yeast mitochondrial ADP/ATP carriers support a domain-based alternating-access transport mechanism.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2014-01-28", "authors": "Ruprecht Jonathan J, Hellawell Alex M, Harding Marilyn, Crichton Paul G, McCoy Airlie J, Kunji Edmund R S", "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" } ], "reference": [ { "type": "PubMed", "id": "24474793", "url": "https://glygen.org/publication/PubMed/24474793" } ] } ], "crossref": [ { "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "24474793", "url": "https://glygen.org/publication/PubMed/24474793", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "KGCGANILRGVAGAGVISMY", "down_seq": "QLQMILFGKKFK", "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "K", "comment": "Loss of transport activity; when associated with K-109 and K-212. Restored transport activity; when associated with D-109; D-112; K-212; D-215 and D-309.", "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" }, { "database": "PubMed", "id": "24474793", "url": "https://glygen.org/publication/PubMed/24474793" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "109", "end_pos": "109" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "73", "end_pos": "73" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "183", "end_pos": "183" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P18239-1.288.288", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P18239-1.309.309", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P18239-1.309.309", "start_pos": 309, "end_pos": 309, "uniprot_canonical_ac": "P18239-1", "length": 318, "uniprot_id": "ADT2_YEAST", "protein_name": "ADP/ATP translocase 2", "refseq_ac": "NP_009523", "refseq_name": "ADP/ATP carrier protein PET9", "gene_name": "PET9", "gene_names_uniprotkb": "PET9; AAC2; YBL0421", "gene_names_refseq": "AAC2; ANC2; PET9", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Structures of yeast mitochondrial ADP/ATP carriers support a domain-based alternating-access transport mechanism.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2014-01-28", "authors": "Ruprecht Jonathan J, Hellawell Alex M, Harding Marilyn, Crichton Paul G, McCoy Airlie J, Kunji Edmund R S", "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" } ], "reference": [ { "type": "PubMed", "id": "24474793", "url": "https://glygen.org/publication/PubMed/24474793" } ] } ], "crossref": [ { "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "24474793", "url": "https://glygen.org/publication/PubMed/24474793", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Q", "start_aa": "Q", "up_seq": "GANILRGVAGAGVISMYDQL", "down_seq": "MILFGKKFK", "mutagenesis": [ { "sequence_org": "Q", "sequence_mut": "D", "comment": "Loss of transport activity; when associated with D-112 and D-215. Restored transport activity; when associated with K-109; D-112; K-212; D-215 and K-306.", "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" }, { "database": "PubMed", "id": "24474793", "url": "https://glygen.org/publication/PubMed/24474793" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "109", "end_pos": "109" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "73", "end_pos": "73" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "183", "end_pos": "183" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P18239-1.306.306", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P18239-1.73.73", "start_pos": 73, "end_pos": 73, "uniprot_canonical_ac": "P18239-1", "length": 318, "uniprot_id": "ADT2_YEAST", "protein_name": "ADP/ATP translocase 2", "refseq_ac": "NP_009523", "refseq_name": "ADP/ATP carrier protein PET9", "gene_name": "PET9", "gene_names_uniprotkb": "PET9; AAC2; YBL0421", "gene_names_refseq": "AAC2; ANC2; PET9", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "The yeast mitochondrial ADP/ATP carrier functions as a monomer in mitochondrial membranes.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-06-26", "authors": "Bamber Lisa, Harding Marilyn, Monn\u00e9 Magnus, Slotboom Dirk-Jan, Kunji Edmund R S", "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" } ], "reference": [ { "type": "PubMed", "id": "17566106", "url": "https://glygen.org/publication/PubMed/17566106" } ] } ], "crossref": [ { "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17566106", "url": "https://glygen.org/publication/PubMed/17566106", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "NQDEMLKQGTLDRKYAGILD", "down_seq": "FKRTATQEGVISFWRGNTAN", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Loss of inhibition by activity regulator 2-sulfonatoethyl-methanethiosulfonate(MTSES); when associated with A-244; A-271 and A-288.", "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" }, { "database": "PubMed", "id": "17566106", "url": "https://glygen.org/publication/PubMed/17566106" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "109", "end_pos": "109" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "73", "end_pos": "73" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "183", "end_pos": "183" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "upstream", "id": "P18239-1.79.79", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P18239-1.85.85", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P18239-1.183.183", "start_pos": 183, "end_pos": 183, "uniprot_canonical_ac": "P18239-1", "length": 318, "uniprot_id": "ADT2_YEAST", "protein_name": "ADP/ATP translocase 2", "refseq_ac": "NP_009523", "refseq_name": "ADP/ATP carrier protein PET9", "gene_name": "PET9", "gene_names_uniprotkb": "PET9; AAC2; YBL0421", "gene_names_refseq": "AAC2; ANC2; PET9", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P18239", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18239" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000000126", "url": "https://www.yeastgenome.org/locus/S000000126", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P18239", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18239", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KKGGARQFNGLIDVYKKTLK", "down_seq": "DGVAGLYRGFLPSVVGIVVY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000126", "url": "https://www.yeastgenome.org/locus/S000000126" }, { "database": "iPTMnet", "id": "P18239", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18239" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser183" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "109", "end_pos": "109" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "73", "end_pos": "73" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "183", "end_pos": "183" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P18239-1.21.21", "start_pos": 21, "end_pos": 21, "uniprot_canonical_ac": "P18239-1", "length": 318, "uniprot_id": "ADT2_YEAST", "protein_name": "ADP/ATP translocase 2", "refseq_ac": "NP_009523", "refseq_name": "ADP/ATP carrier protein PET9", "gene_name": "PET9", "gene_names_uniprotkb": "PET9; AAC2; YBL0421", "gene_names_refseq": "AAC2; ANC2; PET9", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "iPTMnet", "id": "P18239", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18239" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] } ], "crossref": [ { "id": "P18239", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18239", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000126", "url": "https://www.yeastgenome.org/locus/S000000126", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MSSNAQVKTPLPPAPAPKKE", "down_seq": "NFLIDFLMGGVSAAVAKTAA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P18239", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18239" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000126", "url": "https://www.yeastgenome.org/locus/S000000126" } ], "site_lbl": "Ser21" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "109", "end_pos": "109" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "73", "end_pos": "73" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "183", "end_pos": "183" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P18239-1.2.2", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "downstream", "id": "P18239-1.3.3", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P18239-1.9.9", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P18239-1.39.39", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P18239-1.283.283", "start_pos": 283, "end_pos": 283, "uniprot_canonical_ac": "P18239-1", "length": 318, "uniprot_id": "ADT2_YEAST", "protein_name": "ADP/ATP translocase 2", "refseq_ac": "NP_009523", "refseq_name": "ADP/ATP carrier protein PET9", "gene_name": "PET9", "gene_names_uniprotkb": "PET9; AAC2; YBL0421", "gene_names_refseq": "AAC2; ANC2; PET9", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P18239", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18239" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000000126", "url": "https://www.yeastgenome.org/locus/S000000126", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P18239", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18239", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VKYDGAFDCLRKIVAAEGVG", "down_seq": "LFKGCGANILRGVAGAGVIS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000126", "url": "https://www.yeastgenome.org/locus/S000000126" }, { "database": "iPTMnet", "id": "P18239", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18239" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser283" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "109", "end_pos": "109" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "73", "end_pos": "73" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "183", "end_pos": "183" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P18239-1.271.271", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P18239-1.288.288", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P18239-1.2.2", "start_pos": 2, "end_pos": 2, "uniprot_canonical_ac": "P18239-1", "length": 318, "uniprot_id": "ADT2_YEAST", "protein_name": "ADP/ATP translocase 2", "refseq_ac": "NP_009523", "refseq_name": "ADP/ATP carrier protein PET9", "gene_name": "PET9", "gene_names_uniprotkb": "PET9; AAC2; YBL0421", "gene_names_refseq": "AAC2; ANC2; PET9", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P18239", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18239" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000126", "url": "https://www.yeastgenome.org/locus/S000000126", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P18239", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18239", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "M", "down_seq": "SNAQVKTPLPPAPAPKKESN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000126", "url": "https://www.yeastgenome.org/locus/S000000126" }, { "database": "iPTMnet", "id": "P18239", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18239" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser2" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "109", "end_pos": "109" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "73", "end_pos": "73" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "183", "end_pos": "183" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "P18239-1.3.3", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P18239-1.9.9", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P18239-1.21.21", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P18239-1.39.39", "start_pos": 39, "end_pos": 39, "uniprot_canonical_ac": "P18239-1", "length": 318, "uniprot_id": "ADT2_YEAST", "protein_name": "ADP/ATP translocase 2", "refseq_ac": "NP_009523", "refseq_name": "ADP/ATP carrier protein PET9", "gene_name": "PET9", "gene_names_uniprotkb": "PET9; AAC2; YBL0421", "gene_names_refseq": "AAC2; ANC2; PET9", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase.", "journal": "Mol. Cell. Proteomics", "date": "2007", "authors": "Reinders J\u00f6rg, Wagner Karina, Zahedi Rene P, Stojanovski Diana, Eyrich Beate, van der Laan Martin, Rehling Peter, Sickmann Albert, Pfanner Nikolaus, Meisinger Chris", "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" }, { "database": "iPTMnet", "id": "P18239", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18239" } ], "reference": [ { "type": "PubMed", "id": "17761666", "url": "https://glygen.org/publication/PubMed/17761666" } ] } ], "crossref": [ { "id": "P18239", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18239", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17761666", "url": "https://glygen.org/publication/PubMed/17761666", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000126", "url": "https://www.yeastgenome.org/locus/S000000126", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "KESNFLIDFLMGGVSAAVAK", "down_seq": "AASPIERVKLLIQNQDEMLK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P18239", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18239" }, { "database": "PubMed", "id": "17761666", "url": "https://glygen.org/publication/PubMed/17761666" }, { "database": "SGD", "id": "S000000126", "url": "https://www.yeastgenome.org/locus/S000000126" } ], "site_lbl": "Thr39" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "109", "end_pos": "109" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "73", "end_pos": "73" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "183", "end_pos": "183" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P18239-1.21.21", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P18239-1.42.42", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P18239-1.3.3", "start_pos": 3, "end_pos": 3, "uniprot_canonical_ac": "P18239-1", "length": 318, "uniprot_id": "ADT2_YEAST", "protein_name": "ADP/ATP translocase 2", "refseq_ac": "NP_009523", "refseq_name": "ADP/ATP carrier protein PET9", "gene_name": "PET9", "gene_names_uniprotkb": "PET9; AAC2; YBL0421", "gene_names_refseq": "AAC2; ANC2; PET9", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P18239", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18239" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000126", "url": "https://www.yeastgenome.org/locus/S000000126", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P18239", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18239", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MS", "down_seq": "NAQVKTPLPPAPAPKKESNF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000126", "url": "https://www.yeastgenome.org/locus/S000000126" }, { "database": "iPTMnet", "id": "P18239", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18239" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser3" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "109", "end_pos": "109" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "73", "end_pos": "73" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "183", "end_pos": "183" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "P18239-1.2.2", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P18239-1.9.9", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P18239-1.21.21", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P18239-1.42.42", "start_pos": 42, "end_pos": 42, "uniprot_canonical_ac": "P18239-1", "length": 318, "uniprot_id": "ADT2_YEAST", "protein_name": "ADP/ATP translocase 2", "refseq_ac": "NP_009523", "refseq_name": "ADP/ATP carrier protein PET9", "gene_name": "PET9", "gene_names_uniprotkb": "PET9; AAC2; YBL0421", "gene_names_refseq": "AAC2; ANC2; PET9", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase.", "journal": "Mol. Cell. Proteomics", "date": "2007", "authors": "Reinders J\u00f6rg, Wagner Karina, Zahedi Rene P, Stojanovski Diana, Eyrich Beate, van der Laan Martin, Rehling Peter, Sickmann Albert, Pfanner Nikolaus, Meisinger Chris", "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" }, { "database": "iPTMnet", "id": "P18239", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18239" } ], "reference": [ { "type": "PubMed", "id": "17761666", "url": "https://glygen.org/publication/PubMed/17761666" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P18239", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18239" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P18239", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18239" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P18239", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18239", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17761666", "url": "https://glygen.org/publication/PubMed/17761666", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000126", "url": "https://www.yeastgenome.org/locus/S000000126", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NFLIDFLMGGVSAAVAKTAA", "down_seq": "PIERVKLLIQNQDEMLKQGT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P18239", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18239" }, { "database": "PubMed", "id": "17761666", "url": "https://glygen.org/publication/PubMed/17761666" }, { "database": "SGD", "id": "S000000126", "url": "https://www.yeastgenome.org/locus/S000000126" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser42" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "109", "end_pos": "109" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "73", "end_pos": "73" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "183", "end_pos": "183" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P18239-1.39.39", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P18239-1.79.79", "start_pos": 79, "end_pos": 79, "uniprot_canonical_ac": "P18239-1", "length": 318, "uniprot_id": "ADT2_YEAST", "protein_name": "ADP/ATP translocase 2", "refseq_ac": "NP_009523", "refseq_name": "ADP/ATP carrier protein PET9", "gene_name": "PET9", "gene_names_uniprotkb": "PET9; AAC2; YBL0421", "gene_names_refseq": "AAC2; ANC2; PET9", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P18239", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18239" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000126", "url": "https://www.yeastgenome.org/locus/S000000126", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P18239", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18239", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "KQGTLDRKYAGILDCFKRTA", "down_seq": "QEGVISFWRGNTANVIRYFP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000126", "url": "https://www.yeastgenome.org/locus/S000000126" }, { "database": "iPTMnet", "id": "P18239", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18239" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr79" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "109", "end_pos": "109" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "73", "end_pos": "73" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "183", "end_pos": "183" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "P18239-1.73.73", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P18239-1.85.85", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P18239-1.85.85", "start_pos": 85, "end_pos": 85, "uniprot_canonical_ac": "P18239-1", "length": 318, "uniprot_id": "ADT2_YEAST", "protein_name": "ADP/ATP translocase 2", "refseq_ac": "NP_009523", "refseq_name": "ADP/ATP carrier protein PET9", "gene_name": "PET9", "gene_names_uniprotkb": "PET9; AAC2; YBL0421", "gene_names_refseq": "AAC2; ANC2; PET9", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P18239", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18239" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000000126", "url": "https://www.yeastgenome.org/locus/S000000126", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P18239", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18239", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RKYAGILDCFKRTATQEGVI", "down_seq": "FWRGNTANVIRYFPTQALNF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000126", "url": "https://www.yeastgenome.org/locus/S000000126" }, { "database": "iPTMnet", "id": "P18239", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18239" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser85" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "109", "end_pos": "109" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "73", "end_pos": "73" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "183", "end_pos": "183" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P18239-1.73.73", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P18239-1.79.79", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P18239-1.9.9", "start_pos": 9, "end_pos": 9, "uniprot_canonical_ac": "P18239-1", "length": 318, "uniprot_id": "ADT2_YEAST", "protein_name": "ADP/ATP translocase 2", "refseq_ac": "NP_009523", "refseq_name": "ADP/ATP carrier protein PET9", "gene_name": "PET9", "gene_names_uniprotkb": "PET9; AAC2; YBL0421", "gene_names_refseq": "AAC2; ANC2; PET9", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P18239", "url": "https://www.uniprot.org/uniprotkb/P18239" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P18239", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18239" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P18239", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18239" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000126", "url": "https://www.yeastgenome.org/locus/S000000126", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P18239", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18239", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "MSSNAQVK", "down_seq": "PLPPAPAPKKESNFLIDFLM", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000126", "url": "https://www.yeastgenome.org/locus/S000000126" }, { "database": "iPTMnet", "id": "P18239", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18239" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr9" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "109", "end_pos": "109" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "73", "end_pos": "73" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "183", "end_pos": "183" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P18239-1.2.2", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P18239-1.3.3", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P18239-1.21.21", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P18851-1.309.309", "start_pos": 309, "end_pos": 309, "uniprot_canonical_ac": "P18851-1", "length": 423, "uniprot_id": "GBB_YEAST", "protein_name": "Guanine nucleotide-binding protein subunit beta", "refseq_ac": "NP_014855", "refseq_name": "G protein subunit beta", "gene_name": "STE4", "gene_names_uniprotkb": "STE4; YOR50-2", "gene_names_refseq": "HMD2; STE4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P18851", "url": "https://www.uniprot.org/uniprotkb/P18851" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P18851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18851" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000005738", "url": "https://www.yeastgenome.org/locus/S000005738", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P18851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18851", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SDNGAINMYDLRSDCSIATF", "down_seq": "LFRGYEERTPTPTYMAANME", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005738", "url": "https://www.yeastgenome.org/locus/S000005738" }, { "database": "iPTMnet", "id": "P18851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18851" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser309" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "309", "end_pos": "309" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "46", "end_pos": "46" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "upstream", "id": "P18851-1.318.318", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P18851-1.320.320", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P18851-1.322.322", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P18851-1.323.323", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P18851-1.318.318", "start_pos": 318, "end_pos": 318, "uniprot_canonical_ac": "P18851-1", "length": 423, "uniprot_id": "GBB_YEAST", "protein_name": "Guanine nucleotide-binding protein subunit beta", "refseq_ac": "NP_014855", "refseq_name": "G protein subunit beta", "gene_name": "STE4", "gene_names_uniprotkb": "STE4; YOR50-2", "gene_names_refseq": "HMD2; STE4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P18851", "url": "https://www.uniprot.org/uniprotkb/P18851" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Mol. Cell. Proteomics", "date": "2008", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P18851", "url": "https://www.uniprot.org/uniprotkb/P18851" }, { "database": "iPTMnet", "id": "P18851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18851" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P18851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18851" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "crossref": [ { "id": "P18851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18851", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005738", "url": "https://www.yeastgenome.org/locus/S000005738", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "DLRSDCSIATFSLFRGYEER", "down_seq": "PTPTYMAANMEYNTAQSPQT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P18851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18851" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005738", "url": "https://www.yeastgenome.org/locus/S000005738" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Thr318" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "309", "end_pos": "309" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "46", "end_pos": "46" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "P18851-1.309.309", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P18851-1.320.320", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P18851-1.322.322", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P18851-1.323.323", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P18851-1.332.332", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P18851-1.335.335", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P18851-1.338.338", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P18851-1.320.320", "start_pos": 320, "end_pos": 320, "uniprot_canonical_ac": "P18851-1", "length": 423, "uniprot_id": "GBB_YEAST", "protein_name": "Guanine nucleotide-binding protein subunit beta", "refseq_ac": "NP_014855", "refseq_name": "G protein subunit beta", "gene_name": "STE4", "gene_names_uniprotkb": "STE4; YOR50-2", "gene_names_refseq": "HMD2; STE4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P18851", "url": "https://www.uniprot.org/uniprotkb/P18851" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphorylation of the pheromone-responsive Gbeta protein of Saccharomyces cerevisiae does not affect its mating-specific signaling function.", "journal": "Molecular & general genetics : MGG", "date": "1998-06", "authors": "Li E, Cismowski M J, Stone D E", "evidence": [ { "database": "iPTMnet", "id": "P18851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18851" } ], "reference": [ { "type": "PubMed", "id": "9671029", "url": "https://glygen.org/publication/PubMed/9671029" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P18851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18851" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P18851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18851" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P18851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18851", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "9671029", "url": "https://glygen.org/publication/PubMed/9671029", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005738", "url": "https://www.yeastgenome.org/locus/S000005738", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "RSDCSIATFSLFRGYEERTP", "down_seq": "PTYMAANMEYNTAQSPQTLK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P18851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18851" }, { "database": "PubMed", "id": "9671029", "url": "https://glygen.org/publication/PubMed/9671029" }, { "database": "SGD", "id": "S000005738", "url": "https://www.yeastgenome.org/locus/S000005738" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr320" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "309", "end_pos": "309" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "46", "end_pos": "46" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P18851-1.309.309", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P18851-1.318.318", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P18851-1.322.322", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P18851-1.323.323", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P18851-1.332.332", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P18851-1.335.335", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P18851-1.338.338", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P18851-1.322.322", "start_pos": 322, "end_pos": 322, "uniprot_canonical_ac": "P18851-1", "length": 423, "uniprot_id": "GBB_YEAST", "protein_name": "Guanine nucleotide-binding protein subunit beta", "refseq_ac": "NP_014855", "refseq_name": "G protein subunit beta", "gene_name": "STE4", "gene_names_uniprotkb": "STE4; YOR50-2", "gene_names_refseq": "HMD2; STE4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P18851", "url": "https://www.uniprot.org/uniprotkb/P18851" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P18851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18851" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005738", "url": "https://www.yeastgenome.org/locus/S000005738", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P18851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18851", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "DCSIATFSLFRGYEERTPTP", "down_seq": "YMAANMEYNTAQSPQTLKST", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005738", "url": "https://www.yeastgenome.org/locus/S000005738" }, { "database": "iPTMnet", "id": "P18851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18851" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr322" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "309", "end_pos": "309" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "46", "end_pos": "46" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P18851-1.309.309", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P18851-1.318.318", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P18851-1.320.320", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P18851-1.323.323", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P18851-1.332.332", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P18851-1.335.335", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P18851-1.338.338", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P18851-1.323.323", "start_pos": 323, "end_pos": 323, "uniprot_canonical_ac": "P18851-1", "length": 423, "uniprot_id": "GBB_YEAST", "protein_name": "Guanine nucleotide-binding protein subunit beta", "refseq_ac": "NP_014855", "refseq_name": "G protein subunit beta", "gene_name": "STE4", "gene_names_uniprotkb": "STE4; YOR50-2", "gene_names_refseq": "HMD2; STE4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P18851", "url": "https://www.uniprot.org/uniprotkb/P18851" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P18851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18851" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P18851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18851" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000005738", "url": "https://www.yeastgenome.org/locus/S000005738", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P18851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18851", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "CSIATFSLFRGYEERTPTPT", "down_seq": "MAANMEYNTAQSPQTLKSTS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005738", "url": "https://www.yeastgenome.org/locus/S000005738" }, { "database": "iPTMnet", "id": "P18851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18851" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Tyr323" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "309", "end_pos": "309" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "46", "end_pos": "46" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "P18851-1.309.309", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P18851-1.318.318", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P18851-1.320.320", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P18851-1.322.322", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P18851-1.332.332", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P18851-1.335.335", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P18851-1.338.338", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P18851-1.332.332", "start_pos": 332, "end_pos": 332, "uniprot_canonical_ac": "P18851-1", "length": 423, "uniprot_id": "GBB_YEAST", "protein_name": "Guanine nucleotide-binding protein subunit beta", "refseq_ac": "NP_014855", "refseq_name": "G protein subunit beta", "gene_name": "STE4", "gene_names_uniprotkb": "STE4; YOR50-2", "gene_names_refseq": "HMD2; STE4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P18851", "url": "https://www.uniprot.org/uniprotkb/P18851" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science", "date": "2009", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P18851", "url": "https://www.uniprot.org/uniprotkb/P18851" }, { "database": "iPTMnet", "id": "P18851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18851" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P18851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18851" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "crossref": [ { "id": "P18851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18851", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005738", "url": "https://www.yeastgenome.org/locus/S000005738", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "RGYEERTPTPTYMAANMEYN", "down_seq": "AQSPQTLKSTSSSYLDNQGV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P18851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18851" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005738", "url": "https://www.yeastgenome.org/locus/S000005738" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Thr332" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "309", "end_pos": "309" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "46", "end_pos": "46" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "P18851-1.318.318", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P18851-1.320.320", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P18851-1.322.322", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P18851-1.323.323", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P18851-1.335.335", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P18851-1.338.338", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P18851-1.335.335", "start_pos": 335, "end_pos": 335, "uniprot_canonical_ac": "P18851-1", "length": 423, "uniprot_id": "GBB_YEAST", "protein_name": "Guanine nucleotide-binding protein subunit beta", "refseq_ac": "NP_014855", "refseq_name": "G protein subunit beta", "gene_name": "STE4", "gene_names_uniprotkb": "STE4; YOR50-2", "gene_names_refseq": "HMD2; STE4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P18851", "url": "https://www.uniprot.org/uniprotkb/P18851" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphorylation of the pheromone-responsive Gbeta protein of Saccharomyces cerevisiae does not affect its mating-specific signaling function.", "journal": "Molecular & general genetics : MGG", "date": "1998-06", "authors": "Li E, Cismowski M J, Stone D E", "evidence": [ { "database": "iPTMnet", "id": "P18851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18851" } ], "reference": [ { "type": "PubMed", "id": "9671029", "url": "https://glygen.org/publication/PubMed/9671029" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P18851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18851" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P18851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18851" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P18851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18851" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P18851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18851" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P18851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18851", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "9671029", "url": "https://glygen.org/publication/PubMed/9671029", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005738", "url": "https://www.yeastgenome.org/locus/S000005738", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EERTPTPTYMAANMEYNTAQ", "down_seq": "PQTLKSTSSSYLDNQGVVSL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P18851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18851" }, { "database": "PubMed", "id": "9671029", "url": "https://glygen.org/publication/PubMed/9671029" }, { "database": "SGD", "id": "S000005738", "url": "https://www.yeastgenome.org/locus/S000005738" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser335" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "309", "end_pos": "309" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "46", "end_pos": "46" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P18851-1.318.318", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P18851-1.320.320", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P18851-1.322.322", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P18851-1.323.323", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P18851-1.332.332", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P18851-1.338.338", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P18851-1.338.338", "start_pos": 338, "end_pos": 338, "uniprot_canonical_ac": "P18851-1", "length": 423, "uniprot_id": "GBB_YEAST", "protein_name": "Guanine nucleotide-binding protein subunit beta", "refseq_ac": "NP_014855", "refseq_name": "G protein subunit beta", "gene_name": "STE4", "gene_names_uniprotkb": "STE4; YOR50-2", "gene_names_refseq": "HMD2; STE4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P18851", "url": "https://www.uniprot.org/uniprotkb/P18851" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P18851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18851" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000005738", "url": "https://www.yeastgenome.org/locus/S000005738", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P18851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18851", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "TPTPTYMAANMEYNTAQSPQ", "down_seq": "LKSTSSSYLDNQGVVSLDFS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005738", "url": "https://www.yeastgenome.org/locus/S000005738" }, { "database": "iPTMnet", "id": "P18851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18851" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr338" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "309", "end_pos": "309" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "46", "end_pos": "46" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P18851-1.318.318", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "downstream", "id": "P18851-1.320.320", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P18851-1.322.322", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P18851-1.323.323", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P18851-1.332.332", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P18851-1.335.335", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P18851-1.46.46", "start_pos": 46, "end_pos": 46, "uniprot_canonical_ac": "P18851-1", "length": 423, "uniprot_id": "GBB_YEAST", "protein_name": "Guanine nucleotide-binding protein subunit beta", "refseq_ac": "NP_014855", "refseq_name": "G protein subunit beta", "gene_name": "STE4", "gene_names_uniprotkb": "STE4; YOR50-2", "gene_names_refseq": "HMD2; STE4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P18851", "url": "https://www.uniprot.org/uniprotkb/P18851" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P18851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18851" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005738", "url": "https://www.yeastgenome.org/locus/S000005738", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P18851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18851", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QDISAVEDEIQNKIEAARQE", "down_seq": "KQLHAQINKAKHKIQDASLF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005738", "url": "https://www.yeastgenome.org/locus/S000005738" }, { "database": "iPTMnet", "id": "P18851", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P18851" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser46" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "309", "end_pos": "309" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "46", "end_pos": "46" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19073-1.118.118", "start_pos": 118, "end_pos": 118, "uniprot_canonical_ac": "P19073-1", "length": 191, "uniprot_id": "CDC42_YEAST", "protein_name": "Cell division control protein 42", "refseq_ac": "NP_013330", "refseq_name": "Rho family GTPase CDC42", "gene_name": "CDC42", "gene_names_uniprotkb": "CDC42; L8083.13; SRO2", "gene_names_refseq": "CDC42", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19073", "url": "https://www.uniprot.org/uniprotkb/P19073" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Characterization of the Saccharomyces cerevisiae cdc42-1ts allele and new temperature-conditional-lethal cdc42 alleles.", "journal": "Yeast (Chichester, England)", "date": "1997-05", "authors": "Miller P J, Johnson D I", "evidence": [ { "database": "UniProtKB", "id": "P19073", "url": "https://www.uniprot.org/uniprotkb/P19073" } ], "reference": [ { "type": "PubMed", "id": "9178507", "url": "https://glygen.org/publication/PubMed/9178507" } ] } ], "crossref": [ { "id": "P19073", "url": "https://www.uniprot.org/uniprotkb/P19073", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "9178507", "url": "https://glygen.org/publication/PubMed/9178507", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "FPEVHHHCPGVPCLVVGTQI", "down_seq": "LRDDKVIIEKLQRQRLRPIT", "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Dramatically reduces interaction with RGA1.", "evidence": [ { "database": "UniProtKB", "id": "P19073", "url": "https://www.uniprot.org/uniprotkb/P19073" }, { "database": "PubMed", "id": "9178507", "url": "https://glygen.org/publication/PubMed/9178507" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "118", "end_pos": "118" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "142", "end_pos": "142" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "71", "end_pos": "71" }, { "start_pos": "97", "end_pos": "97" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "139", "end_pos": "139" }, { "start_pos": "161", "end_pos": "161" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19073-1.12.12", "start_pos": 12, "end_pos": 12, "uniprot_canonical_ac": "P19073-1", "length": 191, "uniprot_id": "CDC42_YEAST", "protein_name": "Cell division control protein 42", "refseq_ac": "NP_013330", "refseq_name": "Rho family GTPase CDC42", "gene_name": "CDC42", "gene_names_uniprotkb": "CDC42; L8083.13; SRO2", "gene_names_refseq": "CDC42", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19073", "url": "https://www.uniprot.org/uniprotkb/P19073" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Characterization of the Saccharomyces cerevisiae cdc42-1ts allele and new temperature-conditional-lethal cdc42 alleles.", "journal": "Yeast (Chichester, England)", "date": "1997-05", "authors": "Miller P J, Johnson D I", "evidence": [ { "database": "UniProtKB", "id": "P19073", "url": "https://www.uniprot.org/uniprotkb/P19073" } ], "reference": [ { "type": "PubMed", "id": "9178507", "url": "https://glygen.org/publication/PubMed/9178507" } ] } ], "crossref": [ { "id": "P19073", "url": "https://www.uniprot.org/uniprotkb/P19073", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "9178507", "url": "https://glygen.org/publication/PubMed/9178507", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "G", "start_aa": "G", "up_seq": "MQTLKCVVVGD", "down_seq": "AVGKTCLLISYTTNQFPADY", "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "V", "comment": "Enhances interaction with RGA1.", "evidence": [ { "database": "UniProtKB", "id": "P19073", "url": "https://www.uniprot.org/uniprotkb/P19073" }, { "database": "PubMed", "id": "9178507", "url": "https://glygen.org/publication/PubMed/9178507" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "118", "end_pos": "118" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "142", "end_pos": "142" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "71", "end_pos": "71" }, { "start_pos": "97", "end_pos": "97" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "139", "end_pos": "139" }, { "start_pos": "161", "end_pos": "161" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19073-1.142.142", "start_pos": 142, "end_pos": 142, "uniprot_canonical_ac": "P19073-1", "length": 191, "uniprot_id": "CDC42_YEAST", "protein_name": "Cell division control protein 42", "refseq_ac": "NP_013330", "refseq_name": "Rho family GTPase CDC42", "gene_name": "CDC42", "gene_names_uniprotkb": "CDC42; L8083.13; SRO2", "gene_names_refseq": "CDC42", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19073", "url": "https://www.uniprot.org/uniprotkb/P19073" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Characterization of the Saccharomyces cerevisiae cdc42-1ts allele and new temperature-conditional-lethal cdc42 alleles.", "journal": "Yeast (Chichester, England)", "date": "1997-05", "authors": "Miller P J, Johnson D I", "evidence": [ { "database": "UniProtKB", "id": "P19073", "url": "https://www.uniprot.org/uniprotkb/P19073" } ], "reference": [ { "type": "PubMed", "id": "9178507", "url": "https://glygen.org/publication/PubMed/9178507" } ] } ], "crossref": [ { "id": "P19073", "url": "https://www.uniprot.org/uniprotkb/P19073", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "9178507", "url": "https://glygen.org/publication/PubMed/9178507", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "G", "start_aa": "G", "up_seq": "DKVIIEKLQRQRLRPITSEQ", "down_seq": "SRLARELKAVKYVECSALTQ", "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "S", "comment": "In CDC42-1; temperature-sensitive mutant.", "evidence": [ { "database": "UniProtKB", "id": "P19073", "url": "https://www.uniprot.org/uniprotkb/P19073" }, { "database": "PubMed", "id": "9178507", "url": "https://glygen.org/publication/PubMed/9178507" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "118", "end_pos": "118" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "142", "end_pos": "142" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "71", "end_pos": "71" }, { "start_pos": "97", "end_pos": "97" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "139", "end_pos": "139" }, { "start_pos": "161", "end_pos": "161" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P19073-1.139.139", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P19073-1.161.161", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19073-1.188.188", "start_pos": 188, "end_pos": 188, "uniprot_canonical_ac": "P19073-1", "length": 191, "uniprot_id": "CDC42_YEAST", "protein_name": "Cell division control protein 42", "refseq_ac": "NP_013330", "refseq_name": "Rho family GTPase CDC42", "gene_name": "CDC42", "gene_names_uniprotkb": "CDC42; L8083.13; SRO2", "gene_names_refseq": "CDC42", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19073", "url": "https://www.uniprot.org/uniprotkb/P19073" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Characterization of the Saccharomyces cerevisiae cdc42-1ts allele and new temperature-conditional-lethal cdc42 alleles.", "journal": "Yeast (Chichester, England)", "date": "1997-05", "authors": "Miller P J, Johnson D I", "evidence": [ { "database": "UniProtKB", "id": "P19073", "url": "https://www.uniprot.org/uniprotkb/P19073" } ], "reference": [ { "type": "PubMed", "id": "9178507", "url": "https://glygen.org/publication/PubMed/9178507" } ] } ], "crossref": [ { "id": "P19073", "url": "https://www.uniprot.org/uniprotkb/P19073", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "9178507", "url": "https://glygen.org/publication/PubMed/9178507", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "VFDEAIVAALEPPVIKKSKK", "down_seq": "AIL", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Enhances interaction with RGA1.", "evidence": [ { "database": "UniProtKB", "id": "P19073", "url": "https://www.uniprot.org/uniprotkb/P19073" }, { "database": "PubMed", "id": "9178507", "url": "https://glygen.org/publication/PubMed/9178507" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "118", "end_pos": "118" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "142", "end_pos": "142" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "71", "end_pos": "71" }, { "start_pos": "97", "end_pos": "97" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "139", "end_pos": "139" }, { "start_pos": "161", "end_pos": "161" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19073-1.58.58", "start_pos": 58, "end_pos": 58, "uniprot_canonical_ac": "P19073-1", "length": 191, "uniprot_id": "CDC42_YEAST", "protein_name": "Cell division control protein 42", "refseq_ac": "NP_013330", "refseq_name": "Rho family GTPase CDC42", "gene_name": "CDC42", "gene_names_uniprotkb": "CDC42; L8083.13; SRO2", "gene_names_refseq": "CDC42", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19073", "url": "https://www.uniprot.org/uniprotkb/P19073" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Characterization of the Saccharomyces cerevisiae cdc42-1ts allele and new temperature-conditional-lethal cdc42 alleles.", "journal": "Yeast (Chichester, England)", "date": "1997-05", "authors": "Miller P J, Johnson D I", "evidence": [ { "database": "UniProtKB", "id": "P19073", "url": "https://www.uniprot.org/uniprotkb/P19073" } ], "reference": [ { "type": "PubMed", "id": "9178507", "url": "https://glygen.org/publication/PubMed/9178507" } ] } ], "crossref": [ { "id": "P19073", "url": "https://www.uniprot.org/uniprotkb/P19073", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "9178507", "url": "https://glygen.org/publication/PubMed/9178507", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "DNYAVTVMIGDEPYTLGLFD", "down_seq": "AGQEDYDRLRPLSYPSTDVF", "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Temperature-sensitive mutant.", "evidence": [ { "database": "UniProtKB", "id": "P19073", "url": "https://www.uniprot.org/uniprotkb/P19073" }, { "database": "PubMed", "id": "9178507", "url": "https://glygen.org/publication/PubMed/9178507" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "118", "end_pos": "118" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "142", "end_pos": "142" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "71", "end_pos": "71" }, { "start_pos": "97", "end_pos": "97" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "139", "end_pos": "139" }, { "start_pos": "161", "end_pos": "161" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "P19073-1.61.61", "categories": [ "mutagenesis_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P19073-1.71.71", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19073-1.61.61", "start_pos": 61, "end_pos": 61, "uniprot_canonical_ac": "P19073-1", "length": 191, "uniprot_id": "CDC42_YEAST", "protein_name": "Cell division control protein 42", "refseq_ac": "NP_013330", "refseq_name": "Rho family GTPase CDC42", "gene_name": "CDC42", "gene_names_uniprotkb": "CDC42; L8083.13; SRO2", "gene_names_refseq": "CDC42", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19073", "url": "https://www.uniprot.org/uniprotkb/P19073" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Characterization of the Saccharomyces cerevisiae cdc42-1ts allele and new temperature-conditional-lethal cdc42 alleles.", "journal": "Yeast (Chichester, England)", "date": "1997-05", "authors": "Miller P J, Johnson D I", "evidence": [ { "database": "UniProtKB", "id": "P19073", "url": "https://www.uniprot.org/uniprotkb/P19073" } ], "reference": [ { "type": "PubMed", "id": "9178507", "url": "https://glygen.org/publication/PubMed/9178507" } ] } ], "crossref": [ { "id": "P19073", "url": "https://www.uniprot.org/uniprotkb/P19073", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "9178507", "url": "https://glygen.org/publication/PubMed/9178507", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Q", "start_aa": "Q", "up_seq": "AVTVMIGDEPYTLGLFDTAG", "down_seq": "EDYDRLRPLSYPSTDVFLVC", "mutagenesis": [ { "sequence_org": "Q", "sequence_mut": "L", "comment": "Enhances interaction with RGA1.", "evidence": [ { "database": "UniProtKB", "id": "P19073", "url": "https://www.uniprot.org/uniprotkb/P19073" }, { "database": "PubMed", "id": "9178507", "url": "https://glygen.org/publication/PubMed/9178507" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "118", "end_pos": "118" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "142", "end_pos": "142" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "71", "end_pos": "71" }, { "start_pos": "97", "end_pos": "97" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "139", "end_pos": "139" }, { "start_pos": "161", "end_pos": "161" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P19073-1.58.58", "categories": [ "mutagenesis_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P19073-1.71.71", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19073-1.71.71", "start_pos": 71, "end_pos": 71, "uniprot_canonical_ac": "P19073-1", "length": 191, "uniprot_id": "CDC42_YEAST", "protein_name": "Cell division control protein 42", "refseq_ac": "NP_013330", "refseq_name": "Rho family GTPase CDC42", "gene_name": "CDC42", "gene_names_uniprotkb": "CDC42; L8083.13; SRO2", "gene_names_refseq": "CDC42", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19073", "url": "https://www.uniprot.org/uniprotkb/P19073" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Characterization of the Saccharomyces cerevisiae cdc42-1ts allele and new temperature-conditional-lethal cdc42 alleles.", "journal": "Yeast (Chichester, England)", "date": "1997-05", "authors": "Miller P J, Johnson D I", "evidence": [ { "database": "UniProtKB", "id": "P19073", "url": "https://www.uniprot.org/uniprotkb/P19073" } ], "reference": [ { "type": "PubMed", "id": "9178507", "url": "https://glygen.org/publication/PubMed/9178507" } ] } ], "crossref": [ { "id": "P19073", "url": "https://www.uniprot.org/uniprotkb/P19073", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "9178507", "url": "https://glygen.org/publication/PubMed/9178507", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "YTLGLFDTAGQEDYDRLRPL", "down_seq": "YPSTDVFLVCFSVISPPSFE", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "P", "comment": "Temperature-sensitive mutant.", "evidence": [ { "database": "UniProtKB", "id": "P19073", "url": "https://www.uniprot.org/uniprotkb/P19073" }, { "database": "PubMed", "id": "9178507", "url": "https://glygen.org/publication/PubMed/9178507" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "118", "end_pos": "118" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "142", "end_pos": "142" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "71", "end_pos": "71" }, { "start_pos": "97", "end_pos": "97" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "139", "end_pos": "139" }, { "start_pos": "161", "end_pos": "161" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P19073-1.58.58", "categories": [ "mutagenesis_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P19073-1.61.61", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19073-1.97.97", "start_pos": 97, "end_pos": 97, "uniprot_canonical_ac": "P19073-1", "length": 191, "uniprot_id": "CDC42_YEAST", "protein_name": "Cell division control protein 42", "refseq_ac": "NP_013330", "refseq_name": "Rho family GTPase CDC42", "gene_name": "CDC42", "gene_names_uniprotkb": "CDC42; L8083.13; SRO2", "gene_names_refseq": "CDC42", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19073", "url": "https://www.uniprot.org/uniprotkb/P19073" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Characterization of the Saccharomyces cerevisiae cdc42-1ts allele and new temperature-conditional-lethal cdc42 alleles.", "journal": "Yeast (Chichester, England)", "date": "1997-05", "authors": "Miller P J, Johnson D I", "evidence": [ { "database": "UniProtKB", "id": "P19073", "url": "https://www.uniprot.org/uniprotkb/P19073" } ], "reference": [ { "type": "PubMed", "id": "9178507", "url": "https://glygen.org/publication/PubMed/9178507" } ] } ], "crossref": [ { "id": "P19073", "url": "https://www.uniprot.org/uniprotkb/P19073", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "9178507", "url": "https://glygen.org/publication/PubMed/9178507", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "W", "start_aa": "W", "up_seq": "VFLVCFSVISPPSFENVKEK", "down_seq": "FPEVHHHCPGVPCLVVGTQI", "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "R", "comment": "Temperature-sensitive mutant.", "evidence": [ { "database": "UniProtKB", "id": "P19073", "url": "https://www.uniprot.org/uniprotkb/P19073" }, { "database": "PubMed", "id": "9178507", "url": "https://glygen.org/publication/PubMed/9178507" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "118", "end_pos": "118" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "142", "end_pos": "142" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "71", "end_pos": "71" }, { "start_pos": "97", "end_pos": "97" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "139", "end_pos": "139" }, { "start_pos": "161", "end_pos": "161" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19073-1.139.139", "start_pos": 139, "end_pos": 139, "uniprot_canonical_ac": "P19073-1", "length": 191, "uniprot_id": "CDC42_YEAST", "protein_name": "Cell division control protein 42", "refseq_ac": "NP_013330", "refseq_name": "Rho family GTPase CDC42", "gene_name": "CDC42", "gene_names_uniprotkb": "CDC42; L8083.13; SRO2", "gene_names_refseq": "CDC42", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19073", "url": "https://www.uniprot.org/uniprotkb/P19073" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19073", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19073" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004219", "url": "https://www.yeastgenome.org/locus/S000004219", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19073", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19073", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LRDDKVIIEKLQRQRLRPIT", "down_seq": "EQGSRLARELKAVKYVECSA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004219", "url": "https://www.yeastgenome.org/locus/S000004219" }, { "database": "iPTMnet", "id": "P19073", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19073" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser139" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "118", "end_pos": "118" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "142", "end_pos": "142" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "71", "end_pos": "71" }, { "start_pos": "97", "end_pos": "97" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "139", "end_pos": "139" }, { "start_pos": "161", "end_pos": "161" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "P19073-1.142.142", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19073-1.161.161", "start_pos": 161, "end_pos": 161, "uniprot_canonical_ac": "P19073-1", "length": 191, "uniprot_id": "CDC42_YEAST", "protein_name": "Cell division control protein 42", "refseq_ac": "NP_013330", "refseq_name": "Rho family GTPase CDC42", "gene_name": "CDC42", "gene_names_uniprotkb": "CDC42; L8083.13; SRO2", "gene_names_refseq": "CDC42", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19073", "url": "https://www.uniprot.org/uniprotkb/P19073" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19073", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19073" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004219", "url": "https://www.yeastgenome.org/locus/S000004219", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19073", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19073", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "QGSRLARELKAVKYVECSAL", "down_seq": "QRGLKNVFDEAIVAALEPPV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004219", "url": "https://www.yeastgenome.org/locus/S000004219" }, { "database": "iPTMnet", "id": "P19073", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19073" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr161" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "118", "end_pos": "118" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "142", "end_pos": "142" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "71", "end_pos": "71" }, { "start_pos": "97", "end_pos": "97" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "139", "end_pos": "139" }, { "start_pos": "161", "end_pos": "161" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P19073-1.142.142", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.112.112", "start_pos": 112, "end_pos": 112, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "GLY_001160", "url": "https://data.glygen.org/GLY_001160", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PDPSELAAKEEPAKEEAPAP", "down_seq": "PAASAPAPAAAAPAPVAAAA", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr112", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr112" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P19097-1.95.95", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1250.1250", "start_pos": 1250, "end_pos": 1250, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cerulenin-resistant mutants of Saccharomyces cerevisiae with an altered fatty acid synthase gene.", "journal": "Molecular & general genetics : MGG", "date": "1994-07-08", "authors": "Inokoshi J, Tomoda H, Hashimoto H, Watanabe A, Takeshima H, Omura S", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "reference": [ { "type": "PubMed", "id": "8041367", "url": "https://glygen.org/publication/PubMed/8041367" } ] } ], "crossref": [ { "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "8041367", "url": "https://glygen.org/publication/PubMed/8041367", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "G", "start_aa": "G", "up_seq": "DPYEMYKYVHVSEVGNCSGS", "down_seq": "MGGVSALRGMFKDRFKDEPV", "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "S", "comment": "Cerulenin-resistance.", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" }, { "database": "PubMed", "id": "8041367", "url": "https://glygen.org/publication/PubMed/8041367" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "P19097-1.1249.1249", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P19097-1.1255.1255", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1769.1769", "start_pos": 1769, "end_pos": 1769, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Multimeric options for the auto-activation of the Saccharomyces cerevisiae FAS type I megasynthase.", "journal": "Structure (London, England : 1993)", "date": "2009-08-12", "authors": "Johansson Patrik, Mulinacci Barbara, Koestler Caecilia, Vollrath Ronnald, Oesterhelt Dieter, Grininger Martin", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "reference": [ { "type": "PubMed", "id": "19679086", "url": "https://glygen.org/publication/PubMed/19679086" } ] } ], "crossref": [ { "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19679086", "url": "https://glygen.org/publication/PubMed/19679086", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "V", "start_aa": "V", "up_seq": "TIETAKMIENMTKEKVSNGG", "down_seq": "GVDVELITSINVENDTFIER", "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "D", "comment": "Does not affect oligomerization; when associated with S-1771 and L-1773 or S-1771; L-1773; S-1879 and E-1881.", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" }, { "database": "PubMed", "id": "19679086", "url": "https://glygen.org/publication/PubMed/19679086" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P19097-1.1749.1749", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P19097-1.1752.1752", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P19097-1.1770.1770", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P19097-1.1771.1771", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P19097-1.1772.1772", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P19097-1.1773.1773", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P19097-1.1774.1774", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1770.1770", "start_pos": 1770, "end_pos": 1770, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Multimeric options for the auto-activation of the Saccharomyces cerevisiae FAS type I megasynthase.", "journal": "Structure (London, England : 1993)", "date": "2009-08-12", "authors": "Johansson Patrik, Mulinacci Barbara, Koestler Caecilia, Vollrath Ronnald, Oesterhelt Dieter, Grininger Martin", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "reference": [ { "type": "PubMed", "id": "19679086", "url": "https://glygen.org/publication/PubMed/19679086" } ] } ], "crossref": [ { "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19679086", "url": "https://glygen.org/publication/PubMed/19679086", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "G", "start_aa": "G", "up_seq": "IETAKMIENMTKEKVSNGGV", "down_seq": "VDVELITSINVENDTFIERN", "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "D", "comment": "Loss of transferase activity.", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" }, { "database": "PubMed", "id": "19679086", "url": "https://glygen.org/publication/PubMed/19679086" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P19097-1.1752.1752", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P19097-1.1769.1769", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P19097-1.1771.1771", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P19097-1.1772.1772", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P19097-1.1773.1773", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P19097-1.1774.1774", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1771.1771", "start_pos": 1771, "end_pos": 1771, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Multimeric options for the auto-activation of the Saccharomyces cerevisiae FAS type I megasynthase.", "journal": "Structure (London, England : 1993)", "date": "2009-08-12", "authors": "Johansson Patrik, Mulinacci Barbara, Koestler Caecilia, Vollrath Ronnald, Oesterhelt Dieter, Grininger Martin", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "reference": [ { "type": "PubMed", "id": "19679086", "url": "https://glygen.org/publication/PubMed/19679086" } ] } ], "crossref": [ { "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19679086", "url": "https://glygen.org/publication/PubMed/19679086", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "V", "start_aa": "V", "up_seq": "ETAKMIENMTKEKVSNGGVG", "down_seq": "DVELITSINVENDTFIERNF", "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "S", "comment": "Does not affect oligomerization but lacks transferase activity; when associated with D-1769 and L-1773 or D-1769; L-1773; S-1879 and E-1881.", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" }, { "database": "PubMed", "id": "19679086", "url": "https://glygen.org/publication/PubMed/19679086" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P19097-1.1752.1752", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P19097-1.1769.1769", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P19097-1.1770.1770", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P19097-1.1772.1772", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P19097-1.1773.1773", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P19097-1.1774.1774", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1772.1772", "start_pos": 1772, "end_pos": 1772, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Multimeric options for the auto-activation of the Saccharomyces cerevisiae FAS type I megasynthase.", "journal": "Structure (London, England : 1993)", "date": "2009-08-12", "authors": "Johansson Patrik, Mulinacci Barbara, Koestler Caecilia, Vollrath Ronnald, Oesterhelt Dieter, Grininger Martin", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "reference": [ { "type": "PubMed", "id": "19679086", "url": "https://glygen.org/publication/PubMed/19679086" } ] } ], "crossref": [ { "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19679086", "url": "https://glygen.org/publication/PubMed/19679086", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "TAKMIENMTKEKVSNGGVGV", "down_seq": "VELITSINVENDTFIERNFT", "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "S", "comment": "Loss of transferase activity; when associated with S-1774.", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" }, { "database": "PubMed", "id": "19679086", "url": "https://glygen.org/publication/PubMed/19679086" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P19097-1.1752.1752", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P19097-1.1769.1769", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P19097-1.1770.1770", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P19097-1.1771.1771", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P19097-1.1773.1773", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P19097-1.1774.1774", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1773.1773", "start_pos": 1773, "end_pos": 1773, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Multimeric options for the auto-activation of the Saccharomyces cerevisiae FAS type I megasynthase.", "journal": "Structure (London, England : 1993)", "date": "2009-08-12", "authors": "Johansson Patrik, Mulinacci Barbara, Koestler Caecilia, Vollrath Ronnald, Oesterhelt Dieter, Grininger Martin", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "reference": [ { "type": "PubMed", "id": "19679086", "url": "https://glygen.org/publication/PubMed/19679086" } ] } ], "crossref": [ { "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19679086", "url": "https://glygen.org/publication/PubMed/19679086", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "V", "start_aa": "V", "up_seq": "AKMIENMTKEKVSNGGVGVD", "down_seq": "ELITSINVENDTFIERNFTP", "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "L", "comment": "Does not affect oligomerization but lacks transferase activity; when associated with D-1769 and S-1771 or D-1769; S-1771; S-1879 and E-1881.", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" }, { "database": "PubMed", "id": "19679086", "url": "https://glygen.org/publication/PubMed/19679086" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P19097-1.1769.1769", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P19097-1.1770.1770", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P19097-1.1771.1771", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P19097-1.1772.1772", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P19097-1.1774.1774", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1774.1774", "start_pos": 1774, "end_pos": 1774, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Multimeric options for the auto-activation of the Saccharomyces cerevisiae FAS type I megasynthase.", "journal": "Structure (London, England : 1993)", "date": "2009-08-12", "authors": "Johansson Patrik, Mulinacci Barbara, Koestler Caecilia, Vollrath Ronnald, Oesterhelt Dieter, Grininger Martin", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "reference": [ { "type": "PubMed", "id": "19679086", "url": "https://glygen.org/publication/PubMed/19679086" } ] } ], "crossref": [ { "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19679086", "url": "https://glygen.org/publication/PubMed/19679086", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "E", "start_aa": "E", "up_seq": "KMIENMTKEKVSNGGVGVDV", "down_seq": "LITSINVENDTFIERNFTPQ", "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "S", "comment": "Loss of transferase activity; when associated with S-1772.", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" }, { "database": "PubMed", "id": "19679086", "url": "https://glygen.org/publication/PubMed/19679086" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "P19097-1.1769.1769", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P19097-1.1770.1770", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P19097-1.1771.1771", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P19097-1.1772.1772", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P19097-1.1773.1773", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1841.1841", "start_pos": 1841, "end_pos": 1841, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Multimeric options for the auto-activation of the Saccharomyces cerevisiae FAS type I megasynthase.", "journal": "Structure (London, England : 1993)", "date": "2009-08-12", "authors": "Johansson Patrik, Mulinacci Barbara, Koestler Caecilia, Vollrath Ronnald, Oesterhelt Dieter, Grininger Martin", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "reference": [ { "type": "PubMed", "id": "19679086", "url": "https://glygen.org/publication/PubMed/19679086" } ] } ], "crossref": [ { "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19679086", "url": "https://glygen.org/publication/PubMed/19679086", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "KSLGVKSLGGGAALKDIEIV", "down_seq": "VNKNAPAVELHGNAKKAAEE", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Loss off transferase activity.", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" }, { "database": "PubMed", "id": "19679086", "url": "https://glygen.org/publication/PubMed/19679086" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "P19097-1.1827.1827", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1879.1879", "start_pos": 1879, "end_pos": 1879, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Multimeric options for the auto-activation of the Saccharomyces cerevisiae FAS type I megasynthase.", "journal": "Structure (London, England : 1993)", "date": "2009-08-12", "authors": "Johansson Patrik, Mulinacci Barbara, Koestler Caecilia, Vollrath Ronnald, Oesterhelt Dieter, Grininger Martin", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "reference": [ { "type": "PubMed", "id": "19679086", "url": "https://glygen.org/publication/PubMed/19679086" } ] } ], "crossref": [ { "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19679086", "url": "https://glygen.org/publication/PubMed/19679086", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "V", "start_aa": "V", "up_seq": "AEEAGVTDVKVSISHDDLQA", "down_seq": "AVAVSTKK", "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "S", "comment": "Does not affect oligomerization but lacks transferase activity; when associated with D-1769; S-1771; L-1773 and E-1881.", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" }, { "database": "PubMed", "id": "19679086", "url": "https://glygen.org/publication/PubMed/19679086" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "P19097-1.1865.1865", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P19097-1.1870.1870", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P19097-1.1872.1872", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P19097-1.1881.1881", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1881.1881", "start_pos": 1881, "end_pos": 1881, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Multimeric options for the auto-activation of the Saccharomyces cerevisiae FAS type I megasynthase.", "journal": "Structure (London, England : 1993)", "date": "2009-08-12", "authors": "Johansson Patrik, Mulinacci Barbara, Koestler Caecilia, Vollrath Ronnald, Oesterhelt Dieter, Grininger Martin", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "reference": [ { "type": "PubMed", "id": "19679086", "url": "https://glygen.org/publication/PubMed/19679086" } ] } ], "crossref": [ { "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19679086", "url": "https://glygen.org/publication/PubMed/19679086", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "V", "start_aa": "V", "up_seq": "EAGVTDVKVSISHDDLQAVA", "down_seq": "AVSTKK", "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "E", "comment": "Does not affect oligomerization but lacks transferase activity; when associated with D-1769; S-1771; L-1773 and S-1879.", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" }, { "database": "PubMed", "id": "19679086", "url": "https://glygen.org/publication/PubMed/19679086" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P19097-1.1865.1865", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P19097-1.1870.1870", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P19097-1.1872.1872", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P19097-1.1879.1879", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1114.1114", "start_pos": 1114, "end_pos": 1114, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "ETSILEHSGIRLIEPELFNG", "down_seq": "NPEKKEMIQEVIVEEDLEPF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Tyr1114" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1191.1191", "start_pos": 1191, "end_pos": 1191, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "ATLYIPKALRFDRLVAGQIP", "down_seq": "GWNAKTYGISDDIISQVDPI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr1191" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1249.1249", "start_pos": 1249, "end_pos": 1249, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TDPYEMYKYVHVSEVGNCSG", "down_seq": "GMGGVSALRGMFKDRFKDEP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1249" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "P19097-1.1250.1250", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P19097-1.1255.1255", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1255.1255", "start_pos": 1255, "end_pos": 1255, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "YKYVHVSEVGNCSGSGMGGV", "down_seq": "ALRGMFKDRFKDEPVQNDIL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1255" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "P19097-1.1249.1249", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P19097-1.1250.1250", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1349.1349", "start_pos": 1349, "end_pos": 1349, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "VGGYDDFQEEGSFEFGNMKA", "down_seq": "SNTLEEFEHGRTPAEMSRPA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ], "site_lbl": "Thr1349" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "P19097-1.1350.1350", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P19097-1.1352.1352", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P19097-1.1361.1361", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P19097-1.1366.1366", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1350.1350", "start_pos": 1350, "end_pos": 1350, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GGYDDFQEEGSFEFGNMKAT", "down_seq": "NTLEEFEHGRTPAEMSRPAT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1350" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "P19097-1.1349.1349", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P19097-1.1352.1352", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P19097-1.1361.1361", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P19097-1.1366.1366", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P19097-1.1370.1370", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1352.1352", "start_pos": 1352, "end_pos": 1352, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "YDDFQEEGSFEFGNMKATSN", "down_seq": "LEEFEHGRTPAEMSRPATTT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr1352" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P19097-1.1349.1349", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P19097-1.1350.1350", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P19097-1.1361.1361", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P19097-1.1366.1366", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P19097-1.1370.1370", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1361.1361", "start_pos": 1361, "end_pos": 1361, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "FEFGNMKATSNTLEEFEHGR", "down_seq": "PAEMSRPATTTRNGFMEAQG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr1361" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P19097-1.1349.1349", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P19097-1.1350.1350", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P19097-1.1352.1352", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P19097-1.1366.1366", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P19097-1.1370.1370", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1366.1366", "start_pos": 1366, "end_pos": 1366, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MKATSNTLEEFEHGRTPAEM", "down_seq": "RPATTTRNGFMEAQGAGIQI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1366" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P19097-1.1349.1349", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P19097-1.1350.1350", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P19097-1.1352.1352", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P19097-1.1361.1361", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P19097-1.1370.1370", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1370.1370", "start_pos": 1370, "end_pos": 1370, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SNTLEEFEHGRTPAEMSRPA", "down_seq": "TTRNGFMEAQGAGIQIIMQA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr1370" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P19097-1.1350.1350", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "downstream", "id": "P19097-1.1352.1352", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P19097-1.1361.1361", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P19097-1.1366.1366", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1417.1417", "start_pos": 1417, "end_pos": 1417, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GVPIYGIVAMAATATDKIGR", "down_seq": "VPAPGKGILTTAREHHSSVK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Ser1417" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "upstream", "id": "P19097-1.1428.1428", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1428.1428", "start_pos": 1428, "end_pos": 1428, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "ATATDKIGRSVPAPGKGILT", "down_seq": "AREHHSSVKYASPNLNMKYR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr1428" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P19097-1.1417.1417", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P19097-1.1440.1440", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1440.1440", "start_pos": 1440, "end_pos": 1440, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "Journal of proteome research", "date": "2007-03", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Mol. Cell. Proteomics", "date": "2008", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast.", "journal": "Proteomics", "date": "2009-10", "authors": "Gnad Florian, de Godoy Lyris M F, Cox J\u00fcrgen, Neuhauser Nadin, Ren Shubin, Olsen Jesper V, Mann Matthias", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" } ] }, { "title": "Global analysis of the yeast osmotic stress response by quantitative proteomics.", "journal": "Molecular bioSystems", "date": "2009-11", "authors": "Soufi Boumediene, Kelstrup Christian D, Stoehr Gabriele, Fr\u00f6hlich Florian, Walther Tobias C, Olsen Jesper V", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] }, { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "APGKGILTTAREHHSSVKYA", "down_seq": "PNLNMKYRKRQLVTREAQIK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1440" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P19097-1.1428.1428", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 10 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1479.1479", "start_pos": 1479, "end_pos": 1479, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IKDWVENELEALKLEAEEIP", "down_seq": "EDQNEFLLERTREIHNEAES", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1479" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "upstream", "id": "P19097-1.1499.1499", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.148.148", "start_pos": 148, "end_pos": 148, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VAAAAPAAAAAEIADEPVKA", "down_seq": "LLLHVLVAHKLKKSLDSIPM", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Ser148" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "upstream", "id": "P19097-1.162.162", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P19097-1.165.165", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1499.1499", "start_pos": 1499, "end_pos": 1499, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SEDQNEFLLERTREIHNEAE", "down_seq": "QLRAAQQQWGNDFYKRDPRI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1499" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P19097-1.1479.1479", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1567.1567", "start_pos": 1567, "end_pos": 1567, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KANDKNESATINEMMKHLGR", "down_seq": "EGNPVIGVFQKFLTGHPKGA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser1567" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "upstream", "id": "P19097-1.1581.1581", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1581.1581", "start_pos": 1581, "end_pos": 1581, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "MKHLGRSEGNPVIGVFQKFL", "down_seq": "GHPKGAAGAWMMNGALQILN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr1581" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "P19097-1.1567.1567", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.162.162", "start_pos": 162, "end_pos": 162, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DEPVKASLLLHVLVAHKLKK", "down_seq": "LDSIPMSKTIKDLVGGKSTV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser162" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "P19097-1.148.148", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P19097-1.165.165", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P19097-1.169.169", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P19097-1.180.180", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P19097-1.181.181", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1640.1640", "start_pos": 1640, "end_pos": 1640, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QFEYVLYPSKTLKTDGVRAV", "down_seq": "ITSFGFGQKGGQAIVVHPDY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser1640" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "P19097-1.1643.1643", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1643.1643", "start_pos": 1643, "end_pos": 1643, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "YVLYPSKTLKTDGVRAVSIT", "down_seq": "FGFGQKGGQAIVVHPDYLYG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1643" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P19097-1.1640.1640", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.165.165", "start_pos": 165, "end_pos": 165, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VKASLLLHVLVAHKLKKSLD", "down_seq": "IPMSKTIKDLVGGKSTVQNE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser165" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P19097-1.148.148", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P19097-1.162.162", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P19097-1.169.169", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P19097-1.180.180", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P19097-1.181.181", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.169.169", "start_pos": 169, "end_pos": 169, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LLLHVLVAHKLKKSLDSIPM", "down_seq": "KTIKDLVGGKSTVQNEILGD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser169" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P19097-1.162.162", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P19097-1.165.165", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P19097-1.180.180", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P19097-1.181.181", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1728.1728", "start_pos": 1728, "end_pos": 1728, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DELEEDVYLDPLARVSKDKK", "down_seq": "GSLTFNSKNIQSKDSYINAN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1728" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P19097-1.1730.1730", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P19097-1.1732.1732", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P19097-1.1735.1735", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P19097-1.1740.1740", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P19097-1.1744.1744", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1730.1730", "start_pos": 1730, "end_pos": 1730, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LEEDVYLDPLARVSKDKKSG", "down_seq": "LTFNSKNIQSKDSYINANTI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1730" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P19097-1.1728.1728", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P19097-1.1732.1732", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P19097-1.1735.1735", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P19097-1.1740.1740", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P19097-1.1744.1744", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P19097-1.1749.1749", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1732.1732", "start_pos": 1732, "end_pos": 1732, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "EDVYLDPLARVSKDKKSGSL", "down_seq": "FNSKNIQSKDSYINANTIET", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr1732" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P19097-1.1728.1728", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P19097-1.1730.1730", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P19097-1.1735.1735", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P19097-1.1740.1740", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P19097-1.1744.1744", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P19097-1.1749.1749", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P19097-1.1752.1752", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1735.1735", "start_pos": 1735, "end_pos": 1735, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "YLDPLARVSKDKKSGSLTFN", "down_seq": "KNIQSKDSYINANTIETAKM", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1735" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P19097-1.1728.1728", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P19097-1.1730.1730", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P19097-1.1732.1732", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P19097-1.1740.1740", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P19097-1.1744.1744", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P19097-1.1749.1749", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P19097-1.1752.1752", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1740.1740", "start_pos": 1740, "end_pos": 1740, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ARVSKDKKSGSLTFNSKNIQ", "down_seq": "KDSYINANTIETAKMIENMT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Ser1740" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P19097-1.1728.1728", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P19097-1.1730.1730", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P19097-1.1732.1732", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P19097-1.1735.1735", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P19097-1.1744.1744", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P19097-1.1749.1749", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P19097-1.1752.1752", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1744.1744", "start_pos": 1744, "end_pos": 1744, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "KDKKSGSLTFNSKNIQSKDS", "down_seq": "INANTIETAKMIENMTKEKV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Tyr1744" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P19097-1.1728.1728", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P19097-1.1730.1730", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P19097-1.1732.1732", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P19097-1.1735.1735", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P19097-1.1740.1740", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P19097-1.1749.1749", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P19097-1.1752.1752", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1749.1749", "start_pos": 1749, "end_pos": 1749, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "GSLTFNSKNIQSKDSYINAN", "down_seq": "IETAKMIENMTKEKVSNGGV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr1749" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P19097-1.1730.1730", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P19097-1.1732.1732", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P19097-1.1735.1735", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P19097-1.1740.1740", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P19097-1.1744.1744", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P19097-1.1752.1752", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P19097-1.1769.1769", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1752.1752", "start_pos": 1752, "end_pos": 1752, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "TFNSKNIQSKDSYINANTIE", "down_seq": "AKMIENMTKEKVSNGGVGVD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr1752" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P19097-1.1732.1732", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P19097-1.1735.1735", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P19097-1.1740.1740", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P19097-1.1744.1744", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P19097-1.1749.1749", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P19097-1.1769.1769", "categories": [ "mutagenesis_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P19097-1.1770.1770", "categories": [ "mutagenesis_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P19097-1.1771.1771", "categories": [ "mutagenesis_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P19097-1.1772.1772", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.180.180", "start_pos": 180, "end_pos": 180, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ], "crossref": [ { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KKSLDSIPMSKTIKDLVGGK", "down_seq": "TVQNEILGDLGKEFGTTPEK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ], "site_lbl": "Ser180" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P19097-1.162.162", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P19097-1.165.165", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P19097-1.169.169", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P19097-1.181.181", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.181.181", "start_pos": 181, "end_pos": 181, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "KSLDSIPMSKTIKDLVGGKS", "down_seq": "VQNEILGDLGKEFGTTPEKP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ], "site_lbl": "Thr181" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P19097-1.162.162", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P19097-1.165.165", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P19097-1.169.169", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P19097-1.180.180", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1827.1827", "start_pos": 1827, "end_pos": 1827, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SSFAGTWSAKEAVFKSLGVK", "down_seq": "LGGGAALKDIEIVRVNKNAP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1827" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "upstream", "id": "P19097-1.1841.1841", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1865.1865", "start_pos": 1865, "end_pos": 1865, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "NAPAVELHGNAKKAAEEAGV", "down_seq": "DVKVSISHDDLQAVAVAVST", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr1865" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "upstream", "id": "P19097-1.1870.1870", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P19097-1.1872.1872", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P19097-1.1879.1879", "categories": [ "mutagenesis_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P19097-1.1881.1881", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1870.1870", "start_pos": 1870, "end_pos": 1870, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ELHGNAKKAAEEAGVTDVKV", "down_seq": "ISHDDLQAVAVAVSTKK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1870" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "P19097-1.1865.1865", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P19097-1.1872.1872", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P19097-1.1879.1879", "categories": [ "mutagenesis_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P19097-1.1881.1881", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.1872.1872", "start_pos": 1872, "end_pos": 1872, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "HGNAKKAAEEAGVTDVKVSI", "down_seq": "HDDLQAVAVAVSTKK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1872" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P19097-1.1865.1865", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P19097-1.1870.1870", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P19097-1.1879.1879", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P19097-1.1881.1881", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.235.235", "start_pos": 235, "end_pos": 235, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DTFSGALGKQSSSLLSRLIS", "down_seq": "KMPGGFTITVARKYLQTRWG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ], "site_lbl": "Ser235" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "upstream", "id": "P19097-1.244.244", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.244.244", "start_pos": 244, "end_pos": 244, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "QSSSLLSRLISSKMPGGFTI", "down_seq": "VARKYLQTRWGLPSGRQDGV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ], "site_lbl": "Thr244" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "P19097-1.235.235", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P19097-1.258.258", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.258.258", "start_pos": 258, "end_pos": 258, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PGGFTITVARKYLQTRWGLP", "down_seq": "GRQDGVLLVALSNEPAARLG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser258" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "P19097-1.244.244", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.289.289", "start_pos": 289, "end_pos": 289, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LSNEPAARLGSEADAKAFLD", "down_seq": "MAQKYASIVGVDLSSAASAS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser289" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.404.404", "start_pos": 404, "end_pos": 404, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EFFVNGVATSFSRKKARTFD", "down_seq": "SWNWAKQSLLSLYFEIIHGV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser404" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.443.443", "start_pos": 443, "end_pos": 443, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GVLKNVDREVVSEAINIMNR", "down_seq": "NDALIKFMEYHISNTDETKG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser443" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.471.471", "start_pos": 471, "end_pos": 471, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "MEYHISNTDETKGENYQLVK", "down_seq": "LGEQLIENCKQVLDVDPVYK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr471" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.50.50", "start_pos": 50, "end_pos": 50, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.", "journal": "Molecular & cellular proteomics : MCP", "date": "2005-03", "authors": "Gruhler Albrecht, Olsen Jesper V, Mohammed Shabaz, Mortensen Peter, Faergeman Nils J, Mann Matthias, Jensen Ole N", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Mol. Cell. Proteomics", "date": "2008", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] }, { "title": "Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast.", "journal": "Science signaling", "date": "2010-12-21", "authors": "Bodenmiller Bernd, Wanka Stefanie, Kraft Claudine, Urban J\u00f6rg, Campbell David, Pedrioli Patrick G, Gerrits Bertran, Picotti Paola, Lam Henry, Vitek Olga, Brusniak Mi-Youn, Roschitzki Bernd, Zhang Chao, Shokat Kevan M, Schlapbach Ralph, Colman-Lerner Alejandro, Nolan Garry P, Nesvizhskii Alexey I, Peter Matthias, Loewith Robbie, von Mering Christian, Aebersold Ruedi", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ETQDVFLKDFNTERVVEIGP", "down_seq": "PTLAGMAQRTLKNKYESYDA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser50" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P19097-1.52.52", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P19097-1.67.67", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.523.523", "start_pos": 523, "end_pos": 523, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Mol. Cell. Proteomics", "date": "2008", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IDKNGNITYSEEPREKVRKL", "down_seq": "QYVQEMALGGPITKESQPTI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser523" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P19097-1.525.525", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.525.525", "start_pos": 525, "end_pos": 525, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "KNGNITYSEEPREKVRKLSQ", "down_seq": "VQEMALGGPITKESQPTIEE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Tyr525" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P19097-1.523.523", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.52.52", "start_pos": 52, "end_pos": 52, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "QDVFLKDFNTERVVEIGPSP", "down_seq": "LAGMAQRTLKNKYESYDAAL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr52" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P19097-1.50.50", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P19097-1.67.67", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.555.555", "start_pos": 555, "end_pos": 555, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ITKESQPTIEEDLTRVYKAI", "down_seq": "AQADKQDISSSTRVEFEKLY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser555" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "upstream", "id": "P19097-1.564.564", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P19097-1.565.565", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P19097-1.566.566", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P19097-1.567.567", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.564.564", "start_pos": 564, "end_pos": 564, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Mol. Cell. Proteomics", "date": "2008", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EEDLTRVYKAISAQADKQDI", "down_seq": "SSTRVEFEKLYSDLMKFLES", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser564" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "P19097-1.555.555", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P19097-1.565.565", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P19097-1.566.566", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P19097-1.567.567", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P19097-1.576.576", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.565.565", "start_pos": 565, "end_pos": 565, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EDLTRVYKAISAQADKQDIS", "down_seq": "STRVEFEKLYSDLMKFLESS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser565" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "P19097-1.555.555", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P19097-1.564.564", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P19097-1.566.566", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P19097-1.567.567", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P19097-1.576.576", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.566.566", "start_pos": 566, "end_pos": 566, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DLTRVYKAISAQADKQDISS", "down_seq": "TRVEFEKLYSDLMKFLESSK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser566" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P19097-1.555.555", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P19097-1.564.564", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P19097-1.565.565", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P19097-1.567.567", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P19097-1.576.576", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.567.567", "start_pos": 567, "end_pos": 567, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase.", "journal": "Mol. Cell. Proteomics", "date": "2007", "authors": "Reinders J\u00f6rg, Wagner Karina, Zahedi Rene P, Stojanovski Diana, Eyrich Beate, van der Laan Martin, Rehling Peter, Sickmann Albert, Pfanner Nikolaus, Meisinger Chris", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "17761666", "url": "https://glygen.org/publication/PubMed/17761666" } ] } ], "crossref": [ { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17761666", "url": "https://glygen.org/publication/PubMed/17761666", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "LTRVYKAISAQADKQDISSS", "down_seq": "RVEFEKLYSDLMKFLESSKE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "17761666", "url": "https://glygen.org/publication/PubMed/17761666" }, { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" } ], "site_lbl": "Thr567" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P19097-1.555.555", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P19097-1.564.564", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P19097-1.565.565", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P19097-1.566.566", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P19097-1.576.576", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.576.576", "start_pos": 576, "end_pos": 576, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AQADKQDISSSTRVEFEKLY", "down_seq": "DLMKFLESSKEIDPSQTTQL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser576" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P19097-1.564.564", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P19097-1.565.565", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P19097-1.566.566", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P19097-1.567.567", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P19097-1.593.593", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P19097-1.594.594", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.593.593", "start_pos": 593, "end_pos": 593, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "KLYSDLMKFLESSKEIDPSQ", "down_seq": "TQLAGMDVEDALDKDSTKEV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr593" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P19097-1.576.576", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P19097-1.594.594", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P19097-1.609.609", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.594.594", "start_pos": 594, "end_pos": 594, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] } ], "crossref": [ { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "LYSDLMKFLESSKEIDPSQT", "down_seq": "QLAGMDVEDALDKDSTKEVA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" } ], "site_lbl": "Thr594" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P19097-1.576.576", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P19097-1.593.593", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P19097-1.609.609", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.609.609", "start_pos": 609, "end_pos": 609, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DPSQTTQLAGMDVEDALDKD", "down_seq": "TKEVASLPNKSTISKTVSST", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser609" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P19097-1.593.593", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P19097-1.594.594", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P19097-1.615.615", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P19097-1.620.620", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P19097-1.623.623", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P19097-1.627.627", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.615.615", "start_pos": 615, "end_pos": 615, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QLAGMDVEDALDKDSTKEVA", "down_seq": "LPNKSTISKTVSSTIPRETI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser615" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "P19097-1.609.609", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P19097-1.620.620", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P19097-1.623.623", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P19097-1.627.627", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.620.620", "start_pos": 620, "end_pos": 620, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DVEDALDKDSTKEVASLPNK", "down_seq": "TISKTVSSTIPRETIPFLHL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser620" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P19097-1.609.609", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P19097-1.615.615", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P19097-1.623.623", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P19097-1.627.627", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.623.623", "start_pos": 623, "end_pos": 623, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DALDKDSTKEVASLPNKSTI", "down_seq": "KTVSSTIPRETIPFLHLRKK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser623" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "P19097-1.609.609", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P19097-1.615.615", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P19097-1.620.620", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P19097-1.627.627", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.627.627", "start_pos": 627, "end_pos": 627, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KDSTKEVASLPNKSTISKTV", "down_seq": "STIPRETIPFLHLRKKTPAG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser627" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P19097-1.609.609", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P19097-1.615.615", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P19097-1.620.620", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P19097-1.623.623", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P19097-1.644.644", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.644.644", "start_pos": 644, "end_pos": 644, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "KTVSSTIPRETIPFLHLRKK", "down_seq": "PAGDWKYDRQLSSLFLDGLE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr644" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P19097-1.627.627", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P19097-1.656.656", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.656.656", "start_pos": 656, "end_pos": 656, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PFLHLRKKTPAGDWKYDRQL", "down_seq": "SLFLDGLEKAAFNGVTFKDK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser656" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P19097-1.644.644", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.67.67", "start_pos": 67, "end_pos": 67, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IGPSPTLAGMAQRTLKNKYE", "down_seq": "YDAALSLHREILCYSKDAKE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser67" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P19097-1.50.50", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P19097-1.52.52", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P19097-1.73.73", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.687.687", "start_pos": 687, "end_pos": 687, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AFNGVTFKDKYVLITGAGKG", "down_seq": "IGAEVLQGLLQGGAKVVVTT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser687" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.708.708", "start_pos": 708, "end_pos": 708, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IGAEVLQGLLQGGAKVVVTT", "down_seq": "RFSKQVTDYYQSIYAKYGAK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser708" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "P19097-1.711.711", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.711.711", "start_pos": 711, "end_pos": 711, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EVLQGLLQGGAKVVVTTSRF", "down_seq": "KQVTDYYQSIYAKYGAKGST", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser711" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P19097-1.708.708", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.73.73", "start_pos": 73, "end_pos": 73, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LAGMAQRTLKNKYESYDAAL", "down_seq": "LHREILCYSKDAKEIYYTPD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser73" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "P19097-1.67.67", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P19097-1.91.91", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.786.786", "start_pos": 786, "end_pos": 786, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DAIIPFAAIPEQGIELEHID", "down_seq": "KSEFAHRIMLTNILRMMGCV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser786" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P19097-1.788.788", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.788.788", "start_pos": 788, "end_pos": 788, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IIPFAAIPEQGIELEHIDSK", "down_seq": "EFAHRIMLTNILRMMGCVKK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser788" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P19097-1.786.786", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.827.827", "start_pos": 827, "end_pos": 827, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KKQKSARGIETRPAQVILPM", "down_seq": "PNHGTFGGDGMYSESKLSLE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser827" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "upstream", "id": "P19097-1.845.845", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.845.845", "start_pos": 845, "end_pos": 845, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PMSPNHGTFGGDGMYSESKL", "down_seq": "LETLFNRWHSESWANQLTVC", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser845" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P19097-1.827.827", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.879.879", "start_pos": 879, "end_pos": 879, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ANQLTVCGAIIGWTRGTGLM", "down_seq": "ANNIIAEGIEKMGVRTFSQK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser879" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.91.91", "start_pos": 91, "end_pos": 91, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "ALSLHREILCYSKDAKEIYY", "down_seq": "PDPSELAAKEEPAKEEAPAP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr91" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P19097-1.73.73", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P19097-1.95.95", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.920.920", "start_pos": 920, "end_pos": 920, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EMAFNLLGLLTPEVVELCQK", "down_seq": "PVMADLNGGLQFVPELKEFT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser920" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.951.951", "start_pos": 951, "end_pos": 951, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QFVPELKEFTAKLRKELVET", "down_seq": "EVRKAVSIETALEHKVVNGN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Ser951" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "upstream", "id": "P19097-1.958.958", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.958.958", "start_pos": 958, "end_pos": 958, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "Journal of proteome research", "date": "2007-03", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Mol. Cell. Proteomics", "date": "2008", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EFTAKLRKELVETSEVRKAV", "down_seq": "IETALEHKVVNGNSADAAYA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser958" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P19097-1.951.951", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19097-1.95.95", "start_pos": 95, "end_pos": 95, "uniprot_canonical_ac": "P19097-1", "length": 1887, "uniprot_id": "FAS2_YEAST", "protein_name": "Fatty acid synthase subunit alpha", "refseq_ac": "NP_015093", "refseq_name": "trifunctional fatty acid synthase subunit FAS2", "gene_name": "FAS2", "gene_names_uniprotkb": "FAS2; P1409", "gene_names_refseq": "FAS2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19097", "url": "https://www.uniprot.org/uniprotkb/P19097" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "HREILCYSKDAKEIYYTPDP", "down_seq": "ELAAKEEPAKEEAPAPTPAA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006152", "url": "https://www.yeastgenome.org/locus/S000006152" }, { "database": "iPTMnet", "id": "P19097", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19097" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser95" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "112", "end_pos": "112" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1250", "end_pos": "1250" }, { "start_pos": "1769", "end_pos": "1769" }, { "start_pos": "1770", "end_pos": "1770" }, { "start_pos": "1771", "end_pos": "1771" }, { "start_pos": "1772", "end_pos": "1772" }, { "start_pos": "1773", "end_pos": "1773" }, { "start_pos": "1774", "end_pos": "1774" }, { "start_pos": "1841", "end_pos": "1841" }, { "start_pos": "1879", "end_pos": "1879" }, { "start_pos": "1881", "end_pos": "1881" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1114", "end_pos": "1114" }, { "start_pos": "112", "end_pos": "112" }, { "start_pos": "1191", "end_pos": "1191" }, { "start_pos": "1249", "end_pos": "1249" }, { "start_pos": "1255", "end_pos": "1255" }, { "start_pos": "1349", "end_pos": "1349" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1352", "end_pos": "1352" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1366", "end_pos": "1366" }, { "start_pos": "1370", "end_pos": "1370" }, { "start_pos": "1417", "end_pos": "1417" }, { "start_pos": "1428", "end_pos": "1428" }, { "start_pos": "1440", "end_pos": "1440" }, { "start_pos": "1479", "end_pos": "1479" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "1499", "end_pos": "1499" }, { "start_pos": "1567", "end_pos": "1567" }, { "start_pos": "1581", "end_pos": "1581" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "1640", "end_pos": "1640" }, { "start_pos": "1643", "end_pos": "1643" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "1728", "end_pos": "1728" }, { "start_pos": "1730", "end_pos": "1730" }, { "start_pos": "1732", "end_pos": "1732" }, { "start_pos": "1735", "end_pos": "1735" }, { "start_pos": "1740", "end_pos": "1740" }, { "start_pos": "1744", "end_pos": "1744" }, { "start_pos": "1749", "end_pos": "1749" }, { "start_pos": "1752", "end_pos": "1752" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "181", "end_pos": "181" }, { "start_pos": "1827", "end_pos": "1827" }, { "start_pos": "1865", "end_pos": "1865" }, { "start_pos": "1870", "end_pos": "1870" }, { "start_pos": "1872", "end_pos": "1872" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "289", "end_pos": "289" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "443", "end_pos": "443" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "50", "end_pos": "50" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "555", "end_pos": "555" }, { "start_pos": "564", "end_pos": "564" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "593", "end_pos": "593" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "615", "end_pos": "615" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "67", "end_pos": "67" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "708", "end_pos": "708" }, { "start_pos": "711", "end_pos": "711" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "788", "end_pos": "788" }, { "start_pos": "827", "end_pos": "827" }, { "start_pos": "845", "end_pos": "845" }, { "start_pos": "879", "end_pos": "879" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "920", "end_pos": "920" }, { "start_pos": "951", "end_pos": "951" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P19097-1.91.91", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P19097-1.112.112", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19146-1.135.135", "start_pos": 135, "end_pos": 135, "uniprot_canonical_ac": "P19146-1", "length": 181, "uniprot_id": "ARF2_YEAST", "protein_name": "ADP-ribosylation factor 2", "refseq_ac": "NP_010144", "refseq_name": "Arf family GTPase ARF2", "gene_name": "ARF2", "gene_names_uniprotkb": "ARF2; D2165", "gene_names_refseq": "ARF2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19146", "url": "https://www.uniprot.org/uniprotkb/P19146" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P19146", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19146" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19146", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19146" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "crossref": [ { "id": "P19146", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19146", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000002296", "url": "https://www.yeastgenome.org/locus/S000002296", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ELRNAVWLVFANKQDLPEAM", "down_seq": "AAEITEKLGLHSIRNRPWFI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19146", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19146" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000002296", "url": "https://www.yeastgenome.org/locus/S000002296" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Ser135" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "147", "end_pos": "147" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "upstream", "id": "P19146-1.147.147", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19146-1.147.147", "start_pos": 147, "end_pos": 147, "uniprot_canonical_ac": "P19146-1", "length": 181, "uniprot_id": "ARF2_YEAST", "protein_name": "ADP-ribosylation factor 2", "refseq_ac": "NP_010144", "refseq_name": "Arf family GTPase ARF2", "gene_name": "ARF2", "gene_names_uniprotkb": "ARF2; D2165", "gene_names_refseq": "ARF2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19146", "url": "https://www.uniprot.org/uniprotkb/P19146" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-06-19", "authors": "Smolka Marcus B, Albuquerque Claudio P, Chen Sheng-hong, Zhou Huilin", "evidence": [ { "database": "iPTMnet", "id": "P19146", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19146" } ], "reference": [ { "type": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] }, { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P19146", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19146" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "iPTMnet", "id": "P19146", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19146" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19146", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19146" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "crossref": [ { "id": "P19146", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19146", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000002296", "url": "https://www.yeastgenome.org/locus/S000002296", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KQDLPEAMSAAEITEKLGLH", "down_seq": "IRNRPWFIQSTCATSGEGLY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19146", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19146" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000002296", "url": "https://www.yeastgenome.org/locus/S000002296" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Ser147" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "147", "end_pos": "147" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P19146-1.135.135", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19262-1.180.180", "start_pos": 180, "end_pos": 180, "uniprot_canonical_ac": "P19262-1", "length": 463, "uniprot_id": "ODO2_YEAST", "protein_name": "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "refseq_ac": "NP_010432", "refseq_name": "dihydrolipoyl transsuccinylase", "gene_name": "KGD2", "gene_names_uniprotkb": "KGD2; YD8358.05C", "gene_names_refseq": "KGD2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19262", "url": "https://www.uniprot.org/uniprotkb/P19262" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P19262", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19262" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19262", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19262" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000002555", "url": "https://www.yeastgenome.org/locus/S000002555", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19262", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19262", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SKPEPTEQAEPSQGVAAREN", "down_seq": "SEETASKKEAAPKKEAAPKK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000002555", "url": "https://www.yeastgenome.org/locus/S000002555" }, { "database": "iPTMnet", "id": "P19262", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19262" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser180" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "180", "end_pos": "180" }, { "start_pos": "203", "end_pos": "203" }, { "start_pos": "340", "end_pos": "340" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19262-1.203.203", "start_pos": 203, "end_pos": 203, "uniprot_canonical_ac": "P19262-1", "length": 463, "uniprot_id": "ODO2_YEAST", "protein_name": "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "refseq_ac": "NP_010432", "refseq_name": "dihydrolipoyl transsuccinylase", "gene_name": "KGD2", "gene_names_uniprotkb": "KGD2; YD8358.05C", "gene_names_refseq": "KGD2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19262", "url": "https://www.uniprot.org/uniprotkb/P19262" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19262", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19262" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000002555", "url": "https://www.yeastgenome.org/locus/S000002555", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19262", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19262", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "ETASKKEAAPKKEAAPKKEV", "down_seq": "EPKKADQPKKTVSKAQEPPV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000002555", "url": "https://www.yeastgenome.org/locus/S000002555" }, { "database": "iPTMnet", "id": "P19262", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19262" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr203" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "180", "end_pos": "180" }, { "start_pos": "203", "end_pos": "203" }, { "start_pos": "340", "end_pos": "340" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19262-1.340.340", "start_pos": 340, "end_pos": 340, "uniprot_canonical_ac": "P19262-1", "length": 463, "uniprot_id": "ODO2_YEAST", "protein_name": "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "refseq_ac": "NP_010432", "refseq_name": "dihydrolipoyl transsuccinylase", "gene_name": "KGD2", "gene_names_uniprotkb": "KGD2; YD8358.05C", "gene_names_refseq": "KGD2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19262", "url": "https://www.uniprot.org/uniprotkb/P19262" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase.", "journal": "Molecular & cellular proteomics : MCP", "date": "2007-11", "authors": "Reinders J\u00f6rg, Wagner Karina, Zahedi Rene P, Stojanovski Diana, Eyrich Beate, van der Laan Martin, Rehling Peter, Sickmann Albert, Pfanner Nikolaus, Meisinger Chris", "evidence": [ { "database": "UniProtKB", "id": "P19262", "url": "https://www.uniprot.org/uniprotkb/P19262" }, { "database": "iPTMnet", "id": "P19262", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19262" } ], "reference": [ { "type": "PubMed", "id": "17761666", "url": "https://glygen.org/publication/PubMed/17761666" } ] } ], "crossref": [ { "id": "P19262", "url": "https://www.uniprot.org/uniprotkb/P19262", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17761666", "url": "https://glygen.org/publication/PubMed/17761666", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19262", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19262", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000002555", "url": "https://www.yeastgenome.org/locus/S000002555", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "IVYRDYTDISVAVATPKGLV", "down_seq": "PVVRNAESLSVLDIENEIVR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P19262", "url": "https://www.uniprot.org/uniprotkb/P19262" }, { "database": "PubMed", "id": "17761666", "url": "https://glygen.org/publication/PubMed/17761666" }, { "database": "iPTMnet", "id": "P19262", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19262" }, { "database": "SGD", "id": "S000002555", "url": "https://www.yeastgenome.org/locus/S000002555" } ], "site_lbl": "Thr340" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "180", "end_pos": "180" }, { "start_pos": "203", "end_pos": "203" }, { "start_pos": "340", "end_pos": "340" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19358-1.103.103", "start_pos": 103, "end_pos": 103, "uniprot_canonical_ac": "P19358-1", "length": 384, "uniprot_id": "METK2_YEAST", "protein_name": "S-adenosylmethionine synthase 2", "refseq_ac": "NP_010790", "refseq_name": "methionine adenosyltransferase SAM2", "gene_name": "SAM2", "gene_names_uniprotkb": "SAM2; D9719.8; ETH2", "gene_names_refseq": "ETH2; SAM2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19358", "url": "https://www.uniprot.org/uniprotkb/P19358" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19358", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19358" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000002910", "url": "https://www.yeastgenome.org/locus/S000002910", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19358", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19358", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DSAKGFDYKTCNVLVAIEQQ", "down_seq": "PDIAQGLHYEKSLEDLGAGD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000002910", "url": "https://www.yeastgenome.org/locus/S000002910" }, { "database": "iPTMnet", "id": "P19358", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19358" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser103" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "68", "end_pos": "68" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19358-1.161.161", "start_pos": 161, "end_pos": 161, "uniprot_canonical_ac": "P19358-1", "length": 384, "uniprot_id": "METK2_YEAST", "protein_name": "S-adenosylmethionine synthase 2", "refseq_ac": "NP_010790", "refseq_name": "methionine adenosyltransferase SAM2", "gene_name": "SAM2", "gene_names_uniprotkb": "SAM2; D9719.8; ETH2", "gene_names_refseq": "ETH2; SAM2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19358", "url": "https://www.uniprot.org/uniprotkb/P19358" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19358", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19358" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000002910", "url": "https://www.yeastgenome.org/locus/S000002910", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19358", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19358", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LTILLAHKLNMAMADARRDG", "down_seq": "LPWLRPDTKTQVTVEYEDDN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000002910", "url": "https://www.yeastgenome.org/locus/S000002910" }, { "database": "iPTMnet", "id": "P19358", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19358" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser161" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "68", "end_pos": "68" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19358-1.195.195", "start_pos": 195, "end_pos": 195, "uniprot_canonical_ac": "P19358-1", "length": 384, "uniprot_id": "METK2_YEAST", "protein_name": "S-adenosylmethionine synthase 2", "refseq_ac": "NP_010790", "refseq_name": "methionine adenosyltransferase SAM2", "gene_name": "SAM2", "gene_names_uniprotkb": "SAM2; D9719.8; ETH2", "gene_names_refseq": "ETH2; SAM2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19358", "url": "https://www.uniprot.org/uniprotkb/P19358" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-02-13", "authors": "Chi An, Huttenhower Curtis, Geer Lewis Y, Coon Joshua J, Syka John E P, Bai Dina L, Shabanowitz Jeffrey, Burke Daniel J, Troyanskaya Olga G, Hunt Donald F", "evidence": [ { "database": "iPTMnet", "id": "P19358", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19358" } ], "reference": [ { "type": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ], "crossref": [ { "id": "P19358", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19358", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VEYEDDNGRWVPKRIDTVVI", "down_seq": "AQHADEISTADLRTQLQKDI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19358", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19358" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ], "site_lbl": "Ser195" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "68", "end_pos": "68" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19358-1.236.236", "start_pos": 236, "end_pos": 236, "uniprot_canonical_ac": "P19358-1", "length": 384, "uniprot_id": "METK2_YEAST", "protein_name": "S-adenosylmethionine synthase 2", "refseq_ac": "NP_010790", "refseq_name": "methionine adenosyltransferase SAM2", "gene_name": "SAM2", "gene_names_uniprotkb": "SAM2; D9719.8; ETH2", "gene_names_refseq": "ETH2; SAM2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19358", "url": "https://www.uniprot.org/uniprotkb/P19358" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "iPTMnet", "id": "P19358", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19358" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] } ], "crossref": [ { "id": "P19358", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19358", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000002910", "url": "https://www.yeastgenome.org/locus/S000002910", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VEKVIPKDMLDENTKYFIQP", "down_seq": "GRFVIGGPQGDAGLTGRKII", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19358", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19358" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002910", "url": "https://www.yeastgenome.org/locus/S000002910" } ], "site_lbl": "Ser236" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "68", "end_pos": "68" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19358-1.293.293", "start_pos": 293, "end_pos": 293, "uniprot_canonical_ac": "P19358-1", "length": 384, "uniprot_id": "METK2_YEAST", "protein_name": "S-adenosylmethionine synthase 2", "refseq_ac": "NP_010790", "refseq_name": "methionine adenosyltransferase SAM2", "gene_name": "SAM2", "gene_names_uniprotkb": "SAM2; D9719.8; ETH2", "gene_names_refseq": "ETH2; SAM2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19358", "url": "https://www.uniprot.org/uniprotkb/P19358" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "iPTMnet", "id": "P19358", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19358" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] } ], "crossref": [ { "id": "P19358", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19358", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000002910", "url": "https://www.yeastgenome.org/locus/S000002910", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GKDYSKVDRSAAYAARWVAK", "down_seq": "LVAAGLCKRVQVQFSYAIGI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19358", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19358" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002910", "url": "https://www.yeastgenome.org/locus/S000002910" } ], "site_lbl": "Ser293" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "68", "end_pos": "68" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19358-1.330.330", "start_pos": 330, "end_pos": 330, "uniprot_canonical_ac": "P19358-1", "length": 384, "uniprot_id": "METK2_YEAST", "protein_name": "S-adenosylmethionine synthase 2", "refseq_ac": "NP_010790", "refseq_name": "methionine adenosyltransferase SAM2", "gene_name": "SAM2", "gene_names_uniprotkb": "SAM2; D9719.8; ETH2", "gene_names_refseq": "ETH2; SAM2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19358", "url": "https://www.uniprot.org/uniprotkb/P19358" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19358", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19358" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000002910", "url": "https://www.yeastgenome.org/locus/S000002910", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19358", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19358", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AIGIAEPLSLHVDTYGTATK", "down_seq": "DDEIIEIIKKNFDLRPGVLV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000002910", "url": "https://www.yeastgenome.org/locus/S000002910" }, { "database": "iPTMnet", "id": "P19358", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19358" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser330" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "68", "end_pos": "68" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19358-1.68.68", "start_pos": 68, "end_pos": 68, "uniprot_canonical_ac": "P19358-1", "length": 384, "uniprot_id": "METK2_YEAST", "protein_name": "S-adenosylmethionine synthase 2", "refseq_ac": "NP_010790", "refseq_name": "methionine adenosyltransferase SAM2", "gene_name": "SAM2", "gene_names_uniprotkb": "SAM2; D9719.8; ETH2", "gene_names_refseq": "ETH2; SAM2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19358", "url": "https://www.uniprot.org/uniprotkb/P19358" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19358", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19358" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000002910", "url": "https://www.yeastgenome.org/locus/S000002910", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19358", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19358", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "AAKTGMIMVFGEITTKARLD", "down_seq": "QQIVRDTIKKIGYDDSAKGF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000002910", "url": "https://www.yeastgenome.org/locus/S000002910" }, { "database": "iPTMnet", "id": "P19358", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19358" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Tyr68" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "195", "end_pos": "195" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "293", "end_pos": "293" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "68", "end_pos": "68" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.703.703", "start_pos": 703, "end_pos": 703, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [], "crossref": [ { "id": "GLY_001160", "url": "https://data.glygen.org/GLY_001160", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "QQQQQQQQQQQQQQHIYPSS", "down_seq": "PGVANYSAMANAPGNNIPYM", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr703", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P19659-1.746.746", "start_pos": 746, "end_pos": 746, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P19659", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P19659" }, { "database": "O-GlcNAc Atlas", "id": "P19659", "url": "https://oglcnac.org/atlas/detail/P19659" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19659", "url": "https://oglcnac.org/atlas/detail/P19659", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KNTSSMDFLNSMENTPKVPV", "down_seq": "AAATPSLNKTINGKVNGRTK", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser746", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P19659", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P19659" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser746" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P19659-1.728.728", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P19659-1.729.729", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P19659-1.730.730", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P19659-1.736.736", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P19659-1.740.740", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P19659-1.750.750", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P19659-1.752.752", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P19659-1.765.765", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.750.750", "start_pos": 750, "end_pos": 750, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Identifying protein kinase-specific effectors of the osmostress response in yeast.", "journal": "Science signaling", "date": "2017-03-07", "authors": "Romanov Natalie, Hollenstein David Maria, Janschitz Marion, Ammerer Gustav, Anrather Dorothea, Reiter Wolfgang", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "28270554", "url": "https://glygen.org/publication/PubMed/28270554" } ] }, { "title": "Novel interconnections of HOG signaling revealed by combined use of two proteomic software packages.", "journal": "Cell communication and signaling : CCS", "date": "2019-06-17", "authors": "Janschitz Marion, Romanov Natalie, Varnavides Gina, Hollenstein David Maria, G\u00e9recov\u00e1 Gabriela, Ammerer Gustav, Hartl Markus, Reiter Wolfgang", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "31208443", "url": "https://glygen.org/publication/PubMed/31208443" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "GLY_001160", "url": "https://data.glygen.org/GLY_001160", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "28270554", "url": "https://glygen.org/publication/PubMed/28270554", "database": "PubMed", "categories": [ "Other" ] }, { "id": "31208443", "url": "https://glygen.org/publication/PubMed/31208443", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SMDFLNSMENTPKVPVSAAA", "down_seq": "PSLNKTINGKVNGRTKSNTI", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr750", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "28270554", "url": "https://glygen.org/publication/PubMed/28270554" }, { "database": "PubMed", "id": "31208443", "url": "https://glygen.org/publication/PubMed/31208443" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr750" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P19659-1.730.730", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P19659-1.736.736", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P19659-1.740.740", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P19659-1.746.746", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P19659-1.752.752", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P19659-1.765.765", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P19659-1.767.767", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P19659-1.769.769", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.752.752", "start_pos": 752, "end_pos": 752, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P19659", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P19659" }, { "database": "O-GlcNAc Atlas", "id": "P19659", "url": "https://oglcnac.org/atlas/detail/P19659" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19659", "url": "https://oglcnac.org/atlas/detail/P19659", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DFLNSMENTPKVPVSAAATP", "down_seq": "LNKTINGKVNGRTKSNTIPV", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser752", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P19659", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P19659" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser752" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P19659-1.736.736", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P19659-1.740.740", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P19659-1.746.746", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P19659-1.750.750", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P19659-1.765.765", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P19659-1.767.767", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P19659-1.769.769", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.767.767", "start_pos": 767, "end_pos": 767, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P19659", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P19659" }, { "database": "O-GlcNAc Atlas", "id": "P19659", "url": "https://oglcnac.org/atlas/detail/P19659" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast.", "journal": "Proteomics", "date": "2009-10", "authors": "Gnad Florian, de Godoy Lyris M F, Cox J\u00fcrgen, Neuhauser Nadin, Ren Shubin, Olsen Jesper V, Mann Matthias", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" } ] }, { "title": "Global analysis of the yeast osmotic stress response by quantitative proteomics.", "journal": "Molecular bioSystems", "date": "2009-11", "authors": "Soufi Boumediene, Kelstrup Christian D, Stoehr Gabriele, Fr\u00f6hlich Florian, Walther Tobias C, Olsen Jesper V", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19659", "url": "https://oglcnac.org/atlas/detail/P19659", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AAATPSLNKTINGKVNGRTK", "down_seq": "NTIPVTSIPSTNKKLSISNA", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser767", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P19659", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P19659" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser767" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P19659-1.750.750", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P19659-1.752.752", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P19659-1.765.765", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P19659-1.769.769", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P19659-1.773.773", "categories": [ "glycosylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P19659-1.774.774", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P19659-1.777.777", "categories": [ "glycosylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P19659-1.783.783", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P19659-1.785.785", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.769.769", "start_pos": 769, "end_pos": 769, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P19659", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P19659" }, { "database": "O-GlcNAc Atlas", "id": "P19659", "url": "https://oglcnac.org/atlas/detail/P19659" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] }, { "title": "High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast.", "journal": "Proteomics", "date": "2009-10", "authors": "Gnad Florian, de Godoy Lyris M F, Cox J\u00fcrgen, Neuhauser Nadin, Ren Shubin, Olsen Jesper V, Mann Matthias", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" } ] }, { "title": "Global analysis of the yeast osmotic stress response by quantitative proteomics.", "journal": "Molecular bioSystems", "date": "2009-11", "authors": "Soufi Boumediene, Kelstrup Christian D, Stoehr Gabriele, Fr\u00f6hlich Florian, Walther Tobias C, Olsen Jesper V", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19659", "url": "https://oglcnac.org/atlas/detail/P19659", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "ATPSLNKTINGKVNGRTKSN", "down_seq": "IPVTSIPSTNKKLSISNAAS", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr769", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P19659", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P19659" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr769" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P19659-1.750.750", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P19659-1.752.752", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P19659-1.765.765", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P19659-1.767.767", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P19659-1.773.773", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P19659-1.774.774", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P19659-1.777.777", "categories": [ "glycosylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P19659-1.783.783", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P19659-1.785.785", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P19659-1.789.789", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.773.773", "start_pos": 773, "end_pos": 773, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P19659", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P19659" }, { "database": "O-GlcNAc Atlas", "id": "P19659", "url": "https://oglcnac.org/atlas/detail/P19659" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19659", "url": "https://oglcnac.org/atlas/detail/P19659", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "LNKTINGKVNGRTKSNTIPV", "down_seq": "SIPSTNKKLSISNAASQQPT", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr773", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P19659", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P19659" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "P19659-1.765.765", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P19659-1.767.767", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P19659-1.769.769", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P19659-1.774.774", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P19659-1.777.777", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P19659-1.783.783", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P19659-1.785.785", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P19659-1.789.789", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P19659-1.793.793", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.774.774", "start_pos": 774, "end_pos": 774, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P19659", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P19659" }, { "database": "O-GlcNAc Atlas", "id": "P19659", "url": "https://oglcnac.org/atlas/detail/P19659" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19659", "url": "https://oglcnac.org/atlas/detail/P19659", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NKTINGKVNGRTKSNTIPVT", "down_seq": "IPSTNKKLSISNAASQQPTP", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser774", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P19659", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P19659" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "P19659-1.765.765", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P19659-1.767.767", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P19659-1.769.769", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P19659-1.773.773", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P19659-1.777.777", "categories": [ "glycosylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P19659-1.783.783", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P19659-1.785.785", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P19659-1.789.789", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P19659-1.793.793", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.777.777", "start_pos": 777, "end_pos": 777, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P19659", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P19659" }, { "database": "O-GlcNAc Atlas", "id": "P19659", "url": "https://oglcnac.org/atlas/detail/P19659" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19659", "url": "https://oglcnac.org/atlas/detail/P19659", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "INGKVNGRTKSNTIPVTSIP", "down_seq": "TNKKLSISNAASQQPTPRSA", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser777", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P19659", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P19659" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P19659-1.765.765", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P19659-1.767.767", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P19659-1.769.769", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P19659-1.773.773", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P19659-1.774.774", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P19659-1.783.783", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P19659-1.785.785", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P19659-1.789.789", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P19659-1.793.793", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P19659-1.796.796", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.803.803", "start_pos": 803, "end_pos": 803, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P19659", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P19659" }, { "database": "O-GlcNAc Atlas", "id": "P19659", "url": "https://oglcnac.org/atlas/detail/P19659" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast.", "journal": "Proteomics", "date": "2009-10", "authors": "Gnad Florian, de Godoy Lyris M F, Cox J\u00fcrgen, Neuhauser Nadin, Ren Shubin, Olsen Jesper V, Mann Matthias", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" } ] }, { "title": "Global analysis of the yeast osmotic stress response by quantitative proteomics.", "journal": "Molecular bioSystems", "date": "2009-11", "authors": "Soufi Boumediene, Kelstrup Christian D, Stoehr Gabriele, Fr\u00f6hlich Florian, Walther Tobias C, Olsen Jesper V", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] }, { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19659", "url": "https://oglcnac.org/atlas/detail/P19659", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SISNAASQQPTPRSASNTAK", "down_seq": "TPNTNPSPLKTQTKNGTPNP", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser803", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P19659", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P19659" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser803" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P19659-1.783.783", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "downstream", "id": "P19659-1.785.785", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P19659-1.789.789", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P19659-1.793.793", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P19659-1.796.796", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P19659-1.798.798", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P19659-1.800.800", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P19659-1.804.804", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P19659-1.810.810", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P19659-1.820.820", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 9 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.810.810", "start_pos": 810, "end_pos": 810, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P19659", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P19659" }, { "database": "O-GlcNAc Atlas", "id": "P19659", "url": "https://oglcnac.org/atlas/detail/P19659" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast.", "journal": "Proteomics", "date": "2009-10", "authors": "Gnad Florian, de Godoy Lyris M F, Cox J\u00fcrgen, Neuhauser Nadin, Ren Shubin, Olsen Jesper V, Mann Matthias", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" } ] }, { "title": "Global analysis of the yeast osmotic stress response by quantitative proteomics.", "journal": "Molecular bioSystems", "date": "2009-11", "authors": "Soufi Boumediene, Kelstrup Christian D, Stoehr Gabriele, Fr\u00f6hlich Florian, Walther Tobias C, Olsen Jesper V", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19659", "url": "https://oglcnac.org/atlas/detail/P19659", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QQPTPRSASNTAKSTPNTNP", "down_seq": "PLKTQTKNGTPNPNNMKTVQ", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser810", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P19659", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P19659" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser810" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P19659-1.793.793", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P19659-1.796.796", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P19659-1.798.798", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P19659-1.800.800", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P19659-1.803.803", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P19659-1.804.804", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P19659-1.820.820", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P19659-1.828.828", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 9 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P19659", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P19659" }, { "database": "O-GlcNAc Atlas", "id": "P19659", "url": "https://oglcnac.org/atlas/detail/P19659" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19659", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P19659", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P19659", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P19659" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P19659-1.2.2", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.196.199", "start_pos": 196, "end_pos": 199, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Activator Gcn4 employs multiple segments of Med15/Gal11, including the KIX domain, to recruit mediator to target genes in vivo.", "journal": "The Journal of biological chemistry", "date": "2010-01-22", "authors": "Jedidi Iness, Zhang Fan, Qiu Hongfang, Stahl Stephen J, Palmer Ira, Kaufman Joshua D, Nadaud Philippe S, Mukherjee Sujoy, Wingfield Paul T, Jaroniec Christopher P, Hinnebusch Alan G", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "reference": [ { "type": "PubMed", "id": "19940160", "url": "https://glygen.org/publication/PubMed/19940160" } ] } ], "crossref": [ { "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19940160", "url": "https://glygen.org/publication/PubMed/19940160", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "WQQV", "start_aa": "W", "up_seq": "APIPKQLLQRIPNIPPNINT", "down_seq": "TALAQQKLLTPQDMEAAKEV", "mutagenesis": [ { "sequence_org": "WQQV", "sequence_mut": "AQAA", "comment": "Decreases transcription of GCN4-dependent targets. Decreases recruitment of the mediator complex to the upstream activating sequence (UAS) of amino-acid starvation responsive genes. Sensitive to amino acid starvation.", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "PubMed", "id": "19940160", "url": "https://glygen.org/publication/PubMed/19940160" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.29.39", "start_pos": 29, "end_pos": 39, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Activator Gcn4 employs multiple segments of Med15/Gal11, including the KIX domain, to recruit mediator to target genes in vivo.", "journal": "The Journal of biological chemistry", "date": "2010-01-22", "authors": "Jedidi Iness, Zhang Fan, Qiu Hongfang, Stahl Stephen J, Palmer Ira, Kaufman Joshua D, Nadaud Philippe S, Mukherjee Sujoy, Wingfield Paul T, Jaroniec Christopher P, Hinnebusch Alan G", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "reference": [ { "type": "PubMed", "id": "19940160", "url": "https://glygen.org/publication/PubMed/19940160" } ] } ], "crossref": [ { "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19940160", "url": "https://glygen.org/publication/PubMed/19940160", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "MDINTLNGGSS", "start_aa": "M", "up_seq": "KDTLSNAERAKNVNGLLQVL", "down_seq": "DTADKIRIHAKNFEAALFAK", "mutagenesis": [ { "sequence_org": "MDINTLNGGSS", "sequence_mut": "ADIATLNGGAA", "comment": "Decreases the interaction between the mediator complex and GCN4. Decreases transcription of GCN4-dependent targets. Sensitive to amino acid starvation.", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "PubMed", "id": "19940160", "url": "https://glygen.org/publication/PubMed/19940160" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "upstream", "id": "P19659-1.29.43", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.29.43", "start_pos": 29, "end_pos": 43, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Activator Gcn4 employs multiple segments of Med15/Gal11, including the KIX domain, to recruit mediator to target genes in vivo.", "journal": "The Journal of biological chemistry", "date": "2010-01-22", "authors": "Jedidi Iness, Zhang Fan, Qiu Hongfang, Stahl Stephen J, Palmer Ira, Kaufman Joshua D, Nadaud Philippe S, Mukherjee Sujoy, Wingfield Paul T, Jaroniec Christopher P, Hinnebusch Alan G", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "reference": [ { "type": "PubMed", "id": "19940160", "url": "https://glygen.org/publication/PubMed/19940160" } ] } ], "crossref": [ { "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19940160", "url": "https://glygen.org/publication/PubMed/19940160", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "MDINTLNGGSSDTAD", "start_aa": "M", "up_seq": "KDTLSNAERAKNVNGLLQVL", "down_seq": "KIRIHAKNFEAALFAKSSSK", "mutagenesis": [ { "sequence_org": "MDINTLNGGSSDTAD", "sequence_mut": "ADIATANGGAADAAA", "comment": "Decreases the interaction between the mediator complex and GCN4. Decreases transcription of GCN4-dependent targets. Sensitive to amino acid starvation.", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "PubMed", "id": "19940160", "url": "https://glygen.org/publication/PubMed/19940160" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "P19659-1.29.39", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.1003.1003", "start_pos": 1003, "end_pos": 1003, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-06-19", "authors": "Smolka Marcus B, Albuquerque Claudio P, Chen Sheng-hong, Zhou Huilin", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SSSPSTSSNMDVGNPRKRKA", "down_seq": "VLEISPQDSIASVLSPDSNI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1003" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P19659-1.983.983", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "downstream", "id": "P19659-1.984.984", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "downstream", "id": "P19659-1.985.985", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P19659-1.987.987", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P19659-1.988.988", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P19659-1.1008.1008", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P19659-1.1018.1018", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.1008.1008", "start_pos": 1008, "end_pos": 1008, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TSSNMDVGNPRKRKASVLEI", "down_seq": "PQDSIASVLSPDSNIMSDSK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1008" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P19659-1.988.988", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P19659-1.1003.1003", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P19659-1.1018.1018", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.1018.1018", "start_pos": 1018, "end_pos": 1018, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-06-19", "authors": "Smolka Marcus B, Albuquerque Claudio P, Chen Sheng-hong, Zhou Huilin", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RKRKASVLEISPQDSIASVL", "down_seq": "PDSNIMSDSKKIKVDSPDDP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1018" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P19659-1.1003.1003", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P19659-1.1008.1008", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P19659-1.1034.1034", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.1034.1034", "start_pos": 1034, "end_pos": 1034, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "Journal of proteome research", "date": "2007-03", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-02-13", "authors": "Chi An, Huttenhower Curtis, Geer Lewis Y, Coon Joshua J, Syka John E P, Bai Dina L, Shabanowitz Jeffrey, Burke Daniel J, Troyanskaya Olga G, Hunt Donald F", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] }, { "title": "Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-06-19", "authors": "Smolka Marcus B, Albuquerque Claudio P, Chen Sheng-hong, Zhou Huilin", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] }, { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "Global mapping of protein phosphorylation events identifies Ste20, Sch9 and the cell-cycle regulatory kinases Cdc28/Pho85 as mediators of fatty acid starvation responses in Saccharomyces cerevisiae.", "journal": "Molecular bioSystems", "date": "2012-03", "authors": "Pultz Dennis, Bennetzen Martin V, R\u00f8dk\u00e6r Steven Vestergaard, Zimmermann Christine, Enserink Jorrit M, Andersen Jens S, F\u00e6rgeman Nils J", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] }, { "title": "SUMO is a pervasive regulator of meiosis.", "journal": "eLife", "date": "2021-01-27", "authors": "Bhagwat Nikhil R, Owens Shannon N, Ito Masaru, Boinapalli Jay V, Poa Philip, Ditzel Alexander, Kopparapu Srujan, Mahalawat Meghan, Davies Owen Richard, Collins Sean R, Johnson Jeffrey R, Krogan Nevan J, Hunter Neil", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ] } ], "crossref": [ { "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ASVLSPDSNIMSDSKKIKVD", "down_seq": "PDDPFMTKSGATTSEKQEVT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "33502312", "url": "https://glygen.org/publication/PubMed/33502312" } ], "site_lbl": "Ser1034" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P19659-1.1018.1018", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 13 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.163.163", "start_pos": 163, "end_pos": 163, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ], "crossref": [ { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "QLRNQQQQQQQQQQQQRRQL", "down_seq": "PQQQQLVNQMKVAPIPKQLL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ], "site_lbl": "Thr163" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.2.2", "start_pos": 2, "end_pos": 2, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "M", "down_seq": "AAPVQDKDTLSNAERAKNVN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser2" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P19659-1.0.0", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.335.335", "start_pos": 335, "end_pos": 335, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ], "crossref": [ { "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TCKNFEKTQLGSTMTEPVKQ", "down_seq": "FIRKYINQKALRKIQALRDV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" } ], "site_lbl": "Ser335" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.505.505", "start_pos": 505, "end_pos": 505, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "HQPSQQPQQAQQQPNPLHGL", "down_seq": "PTAKDVEVIKQLSLDASKTN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr505" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.728.728", "start_pos": 728, "end_pos": 728, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] } ], "crossref": [ { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "NYSAMANAPGNNIPYMNHKN", "down_seq": "SSMDFLNSMENTPKVPVSAA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ], "site_lbl": "Thr728" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "P19659-1.729.729", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P19659-1.730.730", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P19659-1.736.736", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P19659-1.740.740", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P19659-1.746.746", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.729.729", "start_pos": 729, "end_pos": 729, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Glucose intake hampers PKA-regulated HSP90 chaperone activity.", "journal": "eLife", "date": "2018-12-05", "authors": "Chen Yu-Chen, Jiang Pei-Heng, Chen Hsuan-Ming, Chen Chang-Han, Wang Yi-Ting, Chen Yu-Ju, Yu Chia-Jung, Teng Shu-Chun", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "YSAMANAPGNNIPYMNHKNT", "down_seq": "SMDFLNSMENTPKVPVSAAA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser729" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "P19659-1.728.728", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P19659-1.730.730", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P19659-1.736.736", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P19659-1.740.740", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P19659-1.746.746", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.730.730", "start_pos": 730, "end_pos": 730, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Glucose intake hampers PKA-regulated HSP90 chaperone activity.", "journal": "eLife", "date": "2018-12-05", "authors": "Chen Yu-Chen, Jiang Pei-Heng, Chen Hsuan-Ming, Chen Chang-Han, Wang Yi-Ting, Chen Yu-Ju, Yu Chia-Jung, Teng Shu-Chun", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SAMANAPGNNIPYMNHKNTS", "down_seq": "MDFLNSMENTPKVPVSAAAT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser730" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P19659-1.728.728", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P19659-1.729.729", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P19659-1.736.736", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P19659-1.740.740", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P19659-1.746.746", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P19659-1.750.750", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.736.736", "start_pos": 736, "end_pos": 736, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PGNNIPYMNHKNTSSMDFLN", "down_seq": "MENTPKVPVSAAATPSLNKT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser736" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "P19659-1.728.728", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P19659-1.729.729", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P19659-1.730.730", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P19659-1.740.740", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P19659-1.746.746", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P19659-1.750.750", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P19659-1.752.752", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.740.740", "start_pos": 740, "end_pos": 740, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "IPYMNHKNTSSMDFLNSMEN", "down_seq": "PKVPVSAAATPSLNKTINGK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr740" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P19659-1.728.728", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P19659-1.729.729", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P19659-1.730.730", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P19659-1.736.736", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P19659-1.746.746", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P19659-1.750.750", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P19659-1.752.752", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.765.765", "start_pos": 765, "end_pos": 765, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "crossref": [ { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "VSAAATPSLNKTINGKVNGR", "down_seq": "KSNTIPVTSIPSTNKKLSIS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Thr765" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P19659-1.746.746", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P19659-1.750.750", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P19659-1.752.752", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P19659-1.767.767", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P19659-1.769.769", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P19659-1.773.773", "categories": [ "glycosylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P19659-1.774.774", "categories": [ "glycosylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P19659-1.777.777", "categories": [ "glycosylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P19659-1.783.783", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P19659-1.785.785", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.783.783", "start_pos": 783, "end_pos": 783, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.", "journal": "Molecular & cellular proteomics : MCP", "date": "2005-03", "authors": "Gruhler Albrecht, Olsen Jesper V, Mohammed Shabaz, Mortensen Peter, Faergeman Nils J, Mann Matthias, Jensen Ole N", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast.", "journal": "Proteomics", "date": "2009-10", "authors": "Gnad Florian, de Godoy Lyris M F, Cox J\u00fcrgen, Neuhauser Nadin, Ren Shubin, Olsen Jesper V, Mann Matthias", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" } ] }, { "title": "Global analysis of the yeast osmotic stress response by quantitative proteomics.", "journal": "Molecular bioSystems", "date": "2009-11", "authors": "Soufi Boumediene, Kelstrup Christian D, Stoehr Gabriele, Fr\u00f6hlich Florian, Walther Tobias C, Olsen Jesper V", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] }, { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GRTKSNTIPVTSIPSTNKKL", "down_seq": "ISNAASQQPTPRSASNTAKS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser783" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P19659-1.765.765", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P19659-1.767.767", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P19659-1.769.769", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P19659-1.773.773", "categories": [ "glycosylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P19659-1.774.774", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P19659-1.777.777", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P19659-1.785.785", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P19659-1.789.789", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P19659-1.793.793", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P19659-1.796.796", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P19659-1.798.798", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P19659-1.800.800", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P19659-1.803.803", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 10 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.785.785", "start_pos": 785, "end_pos": 785, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-06-19", "authors": "Smolka Marcus B, Albuquerque Claudio P, Chen Sheng-hong, Zhou Huilin", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.", "journal": "Genes & development", "date": "2009-08-15", "authors": "Huber Alexandre, Bodenmiller Bernd, Uotila Aino, Stahl Michael, Wanka Stefanie, Gerrits Bertran, Aebersold Ruedi, Loewith Robbie", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] }, { "title": "High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast.", "journal": "Proteomics", "date": "2009-10", "authors": "Gnad Florian, de Godoy Lyris M F, Cox J\u00fcrgen, Neuhauser Nadin, Ren Shubin, Olsen Jesper V, Mann Matthias", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" } ] }, { "title": "Global analysis of the yeast osmotic stress response by quantitative proteomics.", "journal": "Molecular bioSystems", "date": "2009-11", "authors": "Soufi Boumediene, Kelstrup Christian D, Stoehr Gabriele, Fr\u00f6hlich Florian, Walther Tobias C, Olsen Jesper V", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] }, { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TKSNTIPVTSIPSTNKKLSI", "down_seq": "NAASQQPTPRSASNTAKSTP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser785" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P19659-1.765.765", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "downstream", "id": "P19659-1.767.767", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P19659-1.769.769", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P19659-1.773.773", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P19659-1.774.774", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P19659-1.777.777", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P19659-1.783.783", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P19659-1.789.789", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P19659-1.793.793", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P19659-1.796.796", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P19659-1.798.798", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P19659-1.800.800", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P19659-1.803.803", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P19659-1.804.804", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 10 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.789.789", "start_pos": 789, "end_pos": 789, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.", "journal": "Genes & development", "date": "2009-08-15", "authors": "Huber Alexandre, Bodenmiller Bernd, Uotila Aino, Stahl Michael, Wanka Stefanie, Gerrits Bertran, Aebersold Ruedi, Loewith Robbie", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TIPVTSIPSTNKKLSISNAA", "down_seq": "QQPTPRSASNTAKSTPNTNP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser789" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P19659-1.769.769", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P19659-1.773.773", "categories": [ "glycosylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P19659-1.774.774", "categories": [ "glycosylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P19659-1.777.777", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P19659-1.783.783", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P19659-1.785.785", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P19659-1.793.793", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P19659-1.796.796", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P19659-1.798.798", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P19659-1.800.800", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P19659-1.803.803", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P19659-1.804.804", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.793.793", "start_pos": 793, "end_pos": 793, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.", "journal": "Genes & development", "date": "2009-08-15", "authors": "Huber Alexandre, Bodenmiller Bernd, Uotila Aino, Stahl Michael, Wanka Stefanie, Gerrits Bertran, Aebersold Ruedi, Loewith Robbie", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "TSIPSTNKKLSISNAASQQP", "down_seq": "PRSASNTAKSTPNTNPSPLK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr793" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P19659-1.773.773", "categories": [ "glycosylation_flag" ] }, { "distance": 19, "direction": "downstream", "id": "P19659-1.774.774", "categories": [ "glycosylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P19659-1.777.777", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P19659-1.783.783", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P19659-1.785.785", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P19659-1.789.789", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P19659-1.796.796", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P19659-1.798.798", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P19659-1.800.800", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P19659-1.803.803", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P19659-1.804.804", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P19659-1.810.810", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 7 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.796.796", "start_pos": 796, "end_pos": 796, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.", "journal": "Genes & development", "date": "2009-08-15", "authors": "Huber Alexandre, Bodenmiller Bernd, Uotila Aino, Stahl Michael, Wanka Stefanie, Gerrits Bertran, Aebersold Ruedi, Loewith Robbie", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "crossref": [ { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PSTNKKLSISNAASQQPTPR", "down_seq": "ASNTAKSTPNTNPSPLKTQT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Ser796" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P19659-1.777.777", "categories": [ "glycosylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P19659-1.783.783", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P19659-1.785.785", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P19659-1.789.789", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P19659-1.793.793", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P19659-1.798.798", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P19659-1.800.800", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P19659-1.803.803", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P19659-1.804.804", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P19659-1.810.810", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.798.798", "start_pos": 798, "end_pos": 798, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.", "journal": "Genes & development", "date": "2009-08-15", "authors": "Huber Alexandre, Bodenmiller Bernd, Uotila Aino, Stahl Michael, Wanka Stefanie, Gerrits Bertran, Aebersold Ruedi, Loewith Robbie", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] } ], "crossref": [ { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TNKKLSISNAASQQPTPRSA", "down_seq": "NTAKSTPNTNPSPLKTQTKN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ], "site_lbl": "Ser798" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P19659-1.783.783", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P19659-1.785.785", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P19659-1.789.789", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P19659-1.793.793", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P19659-1.796.796", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P19659-1.800.800", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P19659-1.803.803", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P19659-1.804.804", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P19659-1.810.810", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.800.800", "start_pos": 800, "end_pos": 800, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast.", "journal": "Proteomics", "date": "2009-10", "authors": "Gnad Florian, de Godoy Lyris M F, Cox J\u00fcrgen, Neuhauser Nadin, Ren Shubin, Olsen Jesper V, Mann Matthias", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" } ] }, { "title": "Global analysis of the yeast osmotic stress response by quantitative proteomics.", "journal": "Molecular bioSystems", "date": "2009-11", "authors": "Soufi Boumediene, Kelstrup Christian D, Stoehr Gabriele, Fr\u00f6hlich Florian, Walther Tobias C, Olsen Jesper V", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ], "crossref": [ { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "KKLSISNAASQQPTPRSASN", "down_seq": "AKSTPNTNPSPLKTQTKNGT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ], "site_lbl": "Thr800" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P19659-1.783.783", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P19659-1.785.785", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P19659-1.789.789", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P19659-1.793.793", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P19659-1.796.796", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P19659-1.798.798", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P19659-1.803.803", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P19659-1.804.804", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P19659-1.810.810", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P19659-1.820.820", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.804.804", "start_pos": 804, "end_pos": 804, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.", "journal": "Genes & development", "date": "2009-08-15", "authors": "Huber Alexandre, Bodenmiller Bernd, Uotila Aino, Stahl Michael, Wanka Stefanie, Gerrits Bertran, Aebersold Ruedi, Loewith Robbie", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "ISNAASQQPTPRSASNTAKS", "down_seq": "PNTNPSPLKTQTKNGTPNPN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr804" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P19659-1.785.785", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P19659-1.789.789", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P19659-1.793.793", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P19659-1.796.796", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P19659-1.798.798", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P19659-1.800.800", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P19659-1.803.803", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P19659-1.810.810", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P19659-1.820.820", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 7 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.820.820", "start_pos": 820, "end_pos": 820, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "TAKSTPNTNPSPLKTQTKNG", "down_seq": "PNPNNMKTVQSPMGAQPSYN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr820" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P19659-1.800.800", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P19659-1.803.803", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P19659-1.804.804", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P19659-1.810.810", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P19659-1.828.828", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P19659-1.831.831", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P19659-1.838.838", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P19659-1.839.839", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.828.828", "start_pos": 828, "end_pos": 828, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast.", "journal": "Proteomics", "date": "2009-10", "authors": "Gnad Florian, de Godoy Lyris M F, Cox J\u00fcrgen, Neuhauser Nadin, Ren Shubin, Olsen Jesper V, Mann Matthias", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" } ] }, { "title": "Global analysis of the yeast osmotic stress response by quantitative proteomics.", "journal": "Molecular bioSystems", "date": "2009-11", "authors": "Soufi Boumediene, Kelstrup Christian D, Stoehr Gabriele, Fr\u00f6hlich Florian, Walther Tobias C, Olsen Jesper V", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] }, { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "NPSPLKTQTKNGTPNPNNMK", "down_seq": "VQSPMGAQPSYNSAIIENAF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr828" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P19659-1.810.810", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P19659-1.820.820", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P19659-1.831.831", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P19659-1.838.838", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P19659-1.839.839", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.831.831", "start_pos": 831, "end_pos": 831, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast.", "journal": "Proteomics", "date": "2009-10", "authors": "Gnad Florian, de Godoy Lyris M F, Cox J\u00fcrgen, Neuhauser Nadin, Ren Shubin, Olsen Jesper V, Mann Matthias", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" } ] }, { "title": "Global analysis of the yeast osmotic stress response by quantitative proteomics.", "journal": "Molecular bioSystems", "date": "2009-11", "authors": "Soufi Boumediene, Kelstrup Christian D, Stoehr Gabriele, Fr\u00f6hlich Florian, Walther Tobias C, Olsen Jesper V", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PLKTQTKNGTPNPNNMKTVQ", "down_seq": "PMGAQPSYNSAIIENAFRKE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser831" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P19659-1.820.820", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P19659-1.828.828", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P19659-1.838.838", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P19659-1.839.839", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.838.838", "start_pos": 838, "end_pos": 838, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "crossref": [ { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NGTPNPNNMKTVQSPMGAQP", "down_seq": "YNSAIIENAFRKEELLLKDL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Ser838" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P19659-1.820.820", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P19659-1.828.828", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P19659-1.831.831", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P19659-1.839.839", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.839.839", "start_pos": 839, "end_pos": 839, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "GTPNPNNMKTVQSPMGAQPS", "down_seq": "NSAIIENAFRKEELLLKDLE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Tyr839" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P19659-1.820.820", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P19659-1.828.828", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P19659-1.831.831", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P19659-1.838.838", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.916.916", "start_pos": 916, "end_pos": 916, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DEEMLTSCTIPKAVVDHING", "down_seq": "GKRKPTKAAQRARDQDSIDI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser916" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.957.957", "start_pos": 957, "end_pos": 957, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SIKDNKLVMKSKFNKSNRSY", "down_seq": "IALSNVAAIFKGIGGNFKDL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser957" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.978.978", "start_pos": 978, "end_pos": 978, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IALSNVAAIFKGIGGNFKDL", "down_seq": "TLVHSSSPSTSSNMDVGNPR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser978" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "P19659-1.979.979", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P19659-1.983.983", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P19659-1.984.984", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P19659-1.985.985", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P19659-1.987.987", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P19659-1.988.988", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.979.979", "start_pos": 979, "end_pos": 979, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "ALSNVAAIFKGIGGNFKDLS", "down_seq": "LVHSSSPSTSSNMDVGNPRK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr979" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "P19659-1.978.978", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P19659-1.983.983", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P19659-1.984.984", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P19659-1.985.985", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P19659-1.987.987", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P19659-1.988.988", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.983.983", "start_pos": 983, "end_pos": 983, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ], "crossref": [ { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VAAIFKGIGGNFKDLSTLVH", "down_seq": "SSPSTSSNMDVGNPRKRKAS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ], "site_lbl": "Ser983" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "P19659-1.978.978", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P19659-1.979.979", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P19659-1.984.984", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P19659-1.985.985", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P19659-1.987.987", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P19659-1.988.988", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P19659-1.1003.1003", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.984.984", "start_pos": 984, "end_pos": 984, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AAIFKGIGGNFKDLSTLVHS", "down_seq": "SPSTSSNMDVGNPRKRKASV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser984" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "P19659-1.978.978", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P19659-1.979.979", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P19659-1.983.983", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P19659-1.985.985", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P19659-1.987.987", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P19659-1.988.988", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P19659-1.1003.1003", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.985.985", "start_pos": 985, "end_pos": 985, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.", "journal": "Molecular & cellular proteomics : MCP", "date": "2005-03", "authors": "Gruhler Albrecht, Olsen Jesper V, Mohammed Shabaz, Mortensen Peter, Faergeman Nils J, Mann Matthias, Jensen Ole N", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" } ] }, { "title": "Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-06-19", "authors": "Smolka Marcus B, Albuquerque Claudio P, Chen Sheng-hong, Zhou Huilin", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast.", "journal": "Science signaling", "date": "2010-12-21", "authors": "Bodenmiller Bernd, Wanka Stefanie, Kraft Claudine, Urban J\u00f6rg, Campbell David, Pedrioli Patrick G, Gerrits Bertran, Picotti Paola, Lam Henry, Vitek Olga, Brusniak Mi-Youn, Roschitzki Bernd, Zhang Chao, Shokat Kevan M, Schlapbach Ralph, Colman-Lerner Alejandro, Nolan Garry P, Nesvizhskii Alexey I, Peter Matthias, Loewith Robbie, von Mering Christian, Aebersold Ruedi", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AIFKGIGGNFKDLSTLVHSS", "down_seq": "PSTSSNMDVGNPRKRKASVL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser985" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P19659-1.978.978", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P19659-1.979.979", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P19659-1.983.983", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P19659-1.984.984", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P19659-1.987.987", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P19659-1.988.988", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P19659-1.1003.1003", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 7 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.987.987", "start_pos": 987, "end_pos": 987, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "crossref": [ { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FKGIGGNFKDLSTLVHSSSP", "down_seq": "TSSNMDVGNPRKRKASVLEI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Ser987" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "P19659-1.978.978", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P19659-1.979.979", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P19659-1.983.983", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P19659-1.984.984", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P19659-1.985.985", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P19659-1.988.988", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P19659-1.1003.1003", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19659-1.988.988", "start_pos": 988, "end_pos": 988, "uniprot_canonical_ac": "P19659-1", "length": 1081, "uniprot_id": "MED15_YEAST", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "refseq_ac": "NP_014591", "refseq_name": "Gal11p", "gene_name": "GAL11", "gene_names_uniprotkb": "GAL11; ABE1; MED15; RAR3; SDS4; SPT13", "gene_names_refseq": "ABE1; GAL11; MED15; RAR3; SDS4; SPT13", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19659", "url": "https://www.uniprot.org/uniprotkb/P19659" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "crossref": [ { "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "KGIGGNFKDLSTLVHSSSPS", "down_seq": "SSNMDVGNPRKRKASVLEIS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005411", "url": "https://www.yeastgenome.org/locus/S000005411" }, { "database": "iPTMnet", "id": "P19659", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19659" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Thr988" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "703", "end_pos": "703" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "773", "end_pos": "773" }, { "start_pos": "774", "end_pos": "774" }, { "start_pos": "777", "end_pos": "777" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "810", "end_pos": "810" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "196", "end_pos": "199" }, { "start_pos": "29", "end_pos": "39" }, { "start_pos": "29", "end_pos": "43" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1008", "end_pos": "1008" }, { "start_pos": "1018", "end_pos": "1018" }, { "start_pos": "1034", "end_pos": "1034" }, { "start_pos": "163", "end_pos": "163" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "335", "end_pos": "335" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "728", "end_pos": "728" }, { "start_pos": "729", "end_pos": "729" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "740", "end_pos": "740" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "752", "end_pos": "752" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "767", "end_pos": "767" }, { "start_pos": "769", "end_pos": "769" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "789", "end_pos": "789" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "796", "end_pos": "796" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "800", "end_pos": "800" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "831", "end_pos": "831" }, { "start_pos": "838", "end_pos": "838" }, { "start_pos": "839", "end_pos": "839" }, { "start_pos": "916", "end_pos": "916" }, { "start_pos": "957", "end_pos": "957" }, { "start_pos": "978", "end_pos": "978" }, { "start_pos": "979", "end_pos": "979" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "984", "end_pos": "984" }, { "start_pos": "985", "end_pos": "985" }, { "start_pos": "987", "end_pos": "987" }, { "start_pos": "988", "end_pos": "988" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "P19659-1.978.978", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P19659-1.979.979", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P19659-1.983.983", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P19659-1.984.984", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P19659-1.985.985", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P19659-1.987.987", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P19659-1.1003.1003", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P19659-1.1008.1008", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.1168.1168", "start_pos": 1168, "end_pos": 1168, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "The E2-E3 interaction in the N-end rule pathway: the RING-H2 finger of E3 is required for the synthesis of multiubiquitin chain.", "journal": "The EMBO journal", "date": "1999", "authors": "Xie Y, Varshavsky A", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "reference": [ { "type": "PubMed", "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257" } ] } ], "crossref": [ { "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "DYKDKKLRQGVNLQETEKER", "down_seq": "RRLAKKHQARLLAKFNNQQT", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "S", "comment": "Impairs interaction with UBC2, but does not affect degradation of N-end rule substrates.", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "PubMed", "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "P19812-1.1169.1169", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P19812-1.1173.1173", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P19812-1.1175.1175", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P19812-1.1183.1183", "categories": [ "mutagenesis_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P19812-1.1186.1186", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.1169.1169", "start_pos": 1169, "end_pos": 1169, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "The E2-E3 interaction in the N-end rule pathway: the RING-H2 finger of E3 is required for the synthesis of multiubiquitin chain.", "journal": "The EMBO journal", "date": "1999", "authors": "Xie Y, Varshavsky A", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "reference": [ { "type": "PubMed", "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257" } ] } ], "crossref": [ { "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "YKDKKLRQGVNLQETEKERK", "down_seq": "RLAKKHQARLLAKFNNQQTK", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "L", "comment": "Impairs interaction with UBC2, but does not affect degradation of N-end rule substrates.", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "PubMed", "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "P19812-1.1168.1168", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P19812-1.1173.1173", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P19812-1.1175.1175", "categories": [ "mutagenesis_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P19812-1.1183.1183", "categories": [ "mutagenesis_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P19812-1.1186.1186", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.1173.1173", "start_pos": 1173, "end_pos": 1173, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "The E2-E3 interaction in the N-end rule pathway: the RING-H2 finger of E3 is required for the synthesis of multiubiquitin chain.", "journal": "The EMBO journal", "date": "1999", "authors": "Xie Y, Varshavsky A", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "reference": [ { "type": "PubMed", "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257" } ] } ], "crossref": [ { "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "KLRQGVNLQETEKERKRRLA", "down_seq": "KHQARLLAKFNNQQTKFMKE", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Impairs interaction with UBC2, but does not affect degradation of N-end rule substrates.", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "PubMed", "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "P19812-1.1168.1168", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P19812-1.1169.1169", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P19812-1.1175.1175", "categories": [ "mutagenesis_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P19812-1.1183.1183", "categories": [ "mutagenesis_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P19812-1.1186.1186", "categories": [ "mutagenesis_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P19812-1.1190.1190", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.1175.1175", "start_pos": 1175, "end_pos": 1175, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Structural insights into Ubr1-mediated N-degron polyubiquitination.", "journal": "Nature", "date": "2021-12", "authors": "Pan Man, Zheng Qingyun, Wang Tian, Liang Lujun, Mao Junxiong, Zuo Chong, Ding Ruichao, Ai Huasong, Xie Yuan, Si Dong, Yu Yuanyuan, Liu Lei, Zhao Minglei", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "reference": [ { "type": "PubMed", "id": "34789879", "url": "https://glygen.org/publication/PubMed/34789879" } ] } ], "crossref": [ { "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "34789879", "url": "https://glygen.org/publication/PubMed/34789879", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "H", "start_aa": "H", "up_seq": "RQGVNLQETEKERKRRLAKK", "down_seq": "QARLLAKFNNQQTKFMKEHE", "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "In DHHY mutant; abolished E3 ubiquitin protein ligase activity; when associated with A-161, A-933 and A-1763. In FQFH mutant; strongly reduced N-end rule-dependent protein degradation; when associated with A-1183, A-1186 and A-1190.", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "PubMed", "id": "34789879", "url": "https://glygen.org/publication/PubMed/34789879" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P19812-1.1168.1168", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P19812-1.1169.1169", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P19812-1.1173.1173", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P19812-1.1183.1183", "categories": [ "mutagenesis_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P19812-1.1186.1186", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P19812-1.1190.1190", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.1183.1183", "start_pos": 1183, "end_pos": 1183, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Structural insights into Ubr1-mediated N-degron polyubiquitination.", "journal": "Nature", "date": "2021-12", "authors": "Pan Man, Zheng Qingyun, Wang Tian, Liang Lujun, Mao Junxiong, Zuo Chong, Ding Ruichao, Ai Huasong, Xie Yuan, Si Dong, Yu Yuanyuan, Liu Lei, Zhao Minglei", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "reference": [ { "type": "PubMed", "id": "34789879", "url": "https://glygen.org/publication/PubMed/34789879" } ] } ], "crossref": [ { "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "34789879", "url": "https://glygen.org/publication/PubMed/34789879", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "F", "start_aa": "F", "up_seq": "TEKERKRRLAKKHQARLLAK", "down_seq": "NNQQTKFMKEHESEFDEQDN", "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "A", "comment": "In FQFH mutant; strongly reduced N-end rule-dependent protein degradation; when associated with A-1175, A-1186 and A-1190.", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "PubMed", "id": "34789879", "url": "https://glygen.org/publication/PubMed/34789879" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P19812-1.1168.1168", "categories": [ "mutagenesis_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P19812-1.1169.1169", "categories": [ "mutagenesis_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P19812-1.1173.1173", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P19812-1.1175.1175", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P19812-1.1186.1186", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P19812-1.1190.1190", "categories": [ "mutagenesis_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P19812-1.1196.1196", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.1186.1186", "start_pos": 1186, "end_pos": 1186, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Structural insights into Ubr1-mediated N-degron polyubiquitination.", "journal": "Nature", "date": "2021-12", "authors": "Pan Man, Zheng Qingyun, Wang Tian, Liang Lujun, Mao Junxiong, Zuo Chong, Ding Ruichao, Ai Huasong, Xie Yuan, Si Dong, Yu Yuanyuan, Liu Lei, Zhao Minglei", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "reference": [ { "type": "PubMed", "id": "34789879", "url": "https://glygen.org/publication/PubMed/34789879" } ] } ], "crossref": [ { "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "34789879", "url": "https://glygen.org/publication/PubMed/34789879", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Q", "start_aa": "Q", "up_seq": "ERKRRLAKKHQARLLAKFNN", "down_seq": "QTKFMKEHESEFDEQDNDVD", "mutagenesis": [ { "sequence_org": "Q", "sequence_mut": "A", "comment": "In FQFH mutant; strongly reduced N-end rule-dependent protein degradation; when associated with A-1175, A-1183 and A-1190.", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "PubMed", "id": "34789879", "url": "https://glygen.org/publication/PubMed/34789879" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P19812-1.1168.1168", "categories": [ "mutagenesis_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P19812-1.1169.1169", "categories": [ "mutagenesis_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P19812-1.1173.1173", "categories": [ "mutagenesis_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P19812-1.1175.1175", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P19812-1.1183.1183", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P19812-1.1190.1190", "categories": [ "mutagenesis_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P19812-1.1196.1196", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.1190.1190", "start_pos": 1190, "end_pos": 1190, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Structural insights into Ubr1-mediated N-degron polyubiquitination.", "journal": "Nature", "date": "2021-12", "authors": "Pan Man, Zheng Qingyun, Wang Tian, Liang Lujun, Mao Junxiong, Zuo Chong, Ding Ruichao, Ai Huasong, Xie Yuan, Si Dong, Yu Yuanyuan, Liu Lei, Zhao Minglei", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "reference": [ { "type": "PubMed", "id": "34789879", "url": "https://glygen.org/publication/PubMed/34789879" } ] } ], "crossref": [ { "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "34789879", "url": "https://glygen.org/publication/PubMed/34789879", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "F", "start_aa": "F", "up_seq": "RLAKKHQARLLAKFNNQQTK", "down_seq": "MKEHESEFDEQDNDVDMVGE", "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "A", "comment": "In FQFH mutant; strongly reduced N-end rule-dependent protein degradation; when associated with A-1175, A-1183 and A-1186.", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "PubMed", "id": "34789879", "url": "https://glygen.org/publication/PubMed/34789879" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P19812-1.1173.1173", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P19812-1.1175.1175", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P19812-1.1183.1183", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P19812-1.1186.1186", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P19812-1.1196.1196", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.1220.1220", "start_pos": 1220, "end_pos": 1220, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "The E2-E3 interaction in the N-end rule pathway: the RING-H2 finger of E3 is required for the synthesis of multiubiquitin chain.", "journal": "The EMBO journal", "date": "1999", "authors": "Xie Y, Varshavsky A", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "reference": [ { "type": "PubMed", "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257" } ] } ], "crossref": [ { "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "EQDNDVDMVGEKVYESEDFT", "down_seq": "ALCQDSSSTDFFVIPAYHDH", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "No effect on interaction with UBC2, but inhibits degradation of N-end rule substrates.", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "PubMed", "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "P19812-1.1223.1223", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.1223.1223", "start_pos": 1223, "end_pos": 1223, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "The E2-E3 interaction in the N-end rule pathway: the RING-H2 finger of E3 is required for the synthesis of multiubiquitin chain.", "journal": "The EMBO journal", "date": "1999", "authors": "Xie Y, Varshavsky A", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "reference": [ { "type": "PubMed", "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257" } ] } ], "crossref": [ { "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "NDVDMVGEKVYESEDFTCAL", "down_seq": "QDSSSTDFFVIPAYHDHSPI", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "No effect on interaction with UBC2, but inhibits degradation of N-end rule substrates.", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "PubMed", "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P19812-1.1220.1220", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.1295.1295", "start_pos": 1295, "end_pos": 1295, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "The E2-E3 interaction in the N-end rule pathway: the RING-H2 finger of E3 is required for the synthesis of multiubiquitin chain.", "journal": "The EMBO journal", "date": "1999", "authors": "Xie Y, Varshavsky A", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "reference": [ { "type": "PubMed", "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257" } ] } ], "crossref": [ { "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "DVLEALKENGSCGSRKVFVS", "down_seq": "NHHIHHNCFKRYVQKKRFSS", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "No effect on interaction with UBC2, but inhibits degradation of N-end rule substrates.", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "PubMed", "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P19812-1.1297.1297", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.1297.1297", "start_pos": 1297, "end_pos": 1297, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "The E2-E3 interaction in the N-end rule pathway: the RING-H2 finger of E3 is required for the synthesis of multiubiquitin chain.", "journal": "The EMBO journal", "date": "1999", "authors": "Xie Y, Varshavsky A", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "reference": [ { "type": "PubMed", "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257" } ] } ], "crossref": [ { "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "H", "start_aa": "H", "up_seq": "LEALKENGSCGSRKVFVSCN", "down_seq": "HIHHNCFKRYVQKKRFSSNA", "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "No effect on interaction with UBC2, but inhibits degradation of N-end rule substrates.", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "PubMed", "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P19812-1.1295.1295", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.1320.1320", "start_pos": 1320, "end_pos": 1320, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "The E2-E3 interaction in the N-end rule pathway: the RING-H2 finger of E3 is required for the synthesis of multiubiquitin chain.", "journal": "The EMBO journal", "date": "1999", "authors": "Xie Y, Varshavsky A", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "reference": [ { "type": "PubMed", "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257" } ] } ], "crossref": [ { "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "HHNCFKRYVQKKRFSSNAFI", "down_seq": "PLCQTFSNCTLPLCQTSKAN", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "No effect on interaction with UBC2, but inhibits degradation of N-end rule substrates.", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "PubMed", "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.145.146", "start_pos": 145, "end_pos": 146, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Substrate-binding sites of UBR1, the ubiquitin ligase of the N-end rule pathway.", "journal": "The Journal of biological chemistry", "date": "2008-08-29", "authors": "Xia Zanxian, Webster Ailsa, Du Fangyong, Piatkov Konstantin, Ghislain Michel, Varshavsky Alexander", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "reference": [ { "type": "PubMed", "id": "18566452", "url": "https://glygen.org/publication/PubMed/18566452" } ] } ], "crossref": [ { "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18566452", "url": "https://glygen.org/publication/PubMed/18566452", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "CV", "start_aa": "C", "up_seq": "RKFKIGEPLYRCHECGCDDT", "down_seq": "LCIHCFNPKDHVNHHVCTDI", "mutagenesis": [ { "sequence_org": "CV", "sequence_mut": "YM", "comment": "Abolished ability to degrade proteins with type-1 N-degrons without affecting ability to degrade proteins with type-2 N-degrons.", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "PubMed", "id": "18566452", "url": "https://glygen.org/publication/PubMed/18566452" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "upstream", "id": "P19812-1.161.161", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.161.161", "start_pos": 161, "end_pos": 161, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Structural insights into Ubr1-mediated N-degron polyubiquitination.", "journal": "Nature", "date": "2021-12", "authors": "Pan Man, Zheng Qingyun, Wang Tian, Liang Lujun, Mao Junxiong, Zuo Chong, Ding Ruichao, Ai Huasong, Xie Yuan, Si Dong, Yu Yuanyuan, Liu Lei, Zhao Minglei", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "reference": [ { "type": "PubMed", "id": "34789879", "url": "https://glygen.org/publication/PubMed/34789879" } ] } ], "crossref": [ { "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "34789879", "url": "https://glygen.org/publication/PubMed/34789879", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "H", "start_aa": "H", "up_seq": "CDDTCVLCIHCFNPKDHVNH", "down_seq": "VCTDICTEFTSGICDCGDEE", "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "In DHHY mutant; abolished E3 ubiquitin protein ligase activity; when associated with A-933, A-1175 and A-1763.", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "PubMed", "id": "34789879", "url": "https://glygen.org/publication/PubMed/34789879" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P19812-1.145.146", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P19812-1.173.173", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P19812-1.176.176", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.173.173", "start_pos": 173, "end_pos": 173, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Substrate-binding sites of UBR1, the ubiquitin ligase of the N-end rule pathway.", "journal": "The Journal of biological chemistry", "date": "2008-08-29", "authors": "Xia Zanxian, Webster Ailsa, Du Fangyong, Piatkov Konstantin, Ghislain Michel, Varshavsky Alexander", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "reference": [ { "type": "PubMed", "id": "18566452", "url": "https://glygen.org/publication/PubMed/18566452" } ] } ], "crossref": [ { "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18566452", "url": "https://glygen.org/publication/PubMed/18566452", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "G", "start_aa": "G", "up_seq": "NPKDHVNHHVCTDICTEFTS", "down_seq": "ICDCGDEEAWNSPLHCKAEE", "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "D", "comment": "Abolished ability to degrade proteins with type-1 N-degrons without affecting ability to degrade proteins with type-2 N-degrons.", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "PubMed", "id": "18566452", "url": "https://glygen.org/publication/PubMed/18566452" } ] }, { "sequence_org": "G", "sequence_mut": "R", "comment": "Abolished ability to degrade proteins with type-1 N-degrons without affecting ability to degrade proteins with type-2 N-degrons.", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "PubMed", "id": "18566452", "url": "https://glygen.org/publication/PubMed/18566452" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P19812-1.161.161", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P19812-1.176.176", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.1763.1763", "start_pos": 1763, "end_pos": 1763, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Structural insights into Ubr1-mediated N-degron polyubiquitination.", "journal": "Nature", "date": "2021-12", "authors": "Pan Man, Zheng Qingyun, Wang Tian, Liang Lujun, Mao Junxiong, Zuo Chong, Ding Ruichao, Ai Huasong, Xie Yuan, Si Dong, Yu Yuanyuan, Liu Lei, Zhao Minglei", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "reference": [ { "type": "PubMed", "id": "34789879", "url": "https://glygen.org/publication/PubMed/34789879" } ] } ], "crossref": [ { "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "34789879", "url": "https://glygen.org/publication/PubMed/34789879", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "H", "start_aa": "H", "up_seq": "CLHLTQPPSNIFISAPYLNS", "down_seq": "GEVGRNAMRRGDLTTLNLKR", "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "In DHHY mutant; abolished E3 ubiquitin protein ligase activity; when associated with A-161, A-933 and A-1175.", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "PubMed", "id": "34789879", "url": "https://glygen.org/publication/PubMed/34789879" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.176.176", "start_pos": 176, "end_pos": 176, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Substrate-binding sites of UBR1, the ubiquitin ligase of the N-end rule pathway.", "journal": "The Journal of biological chemistry", "date": "2008-08-29", "authors": "Xia Zanxian, Webster Ailsa, Du Fangyong, Piatkov Konstantin, Ghislain Michel, Varshavsky Alexander", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "reference": [ { "type": "PubMed", "id": "18566452", "url": "https://glygen.org/publication/PubMed/18566452" } ] } ], "crossref": [ { "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18566452", "url": "https://glygen.org/publication/PubMed/18566452", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "DHVNHHVCTDICTEFTSGIC", "down_seq": "CGDEEAWNSPLHCKAEEQEN", "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "E", "comment": "Abolished ability to degrade proteins with type-1 N-degrons without affecting ability to degrade proteins with type-2 N-degrons.", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "PubMed", "id": "18566452", "url": "https://glygen.org/publication/PubMed/18566452" } ] }, { "sequence_org": "D", "sequence_mut": "N", "comment": "Abolished ability to degrade proteins with type-1 N-degrons without affecting ability to degrade proteins with type-2 N-degrons.", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "PubMed", "id": "18566452", "url": "https://glygen.org/publication/PubMed/18566452" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P19812-1.161.161", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P19812-1.173.173", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.313.313", "start_pos": 313, "end_pos": 313, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "The E2-E3 interaction in the N-end rule pathway: the RING-H2 finger of E3 is required for the synthesis of multiubiquitin chain.", "journal": "The EMBO journal", "date": "1999", "authors": "Xie Y, Varshavsky A", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "reference": [ { "type": "PubMed", "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257" } ] } ], "crossref": [ { "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "V", "start_aa": "V", "up_seq": "PSNSPEASPSLAKIDPENYT", "down_seq": "IIYNDEYHNYSQATTALRQG", "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "I", "comment": "Abolished ability to degrade proteins with type-2 N-degrons without affecting ability to degrade proteins with type-1 N-degrons.", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "PubMed", "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P19812-1.294.294", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P19812-1.296.296", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P19812-1.300.300", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P19812-1.302.302", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P19812-1.318.318", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P19812-1.321.321", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.318.318", "start_pos": 318, "end_pos": 318, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "The E2-E3 interaction in the N-end rule pathway: the RING-H2 finger of E3 is required for the synthesis of multiubiquitin chain.", "journal": "The EMBO journal", "date": "1999", "authors": "Xie Y, Varshavsky A", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "reference": [ { "type": "PubMed", "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257" } ] } ], "crossref": [ { "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "EASPSLAKIDPENYTVIIYN", "down_seq": "EYHNYSQATTALRQGVPDNV", "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "N", "comment": "Abolished ability to degrade proteins with type-2 N-degrons without affecting ability to degrade proteins with type-1 N-degrons.", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "PubMed", "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P19812-1.300.300", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P19812-1.302.302", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P19812-1.313.313", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P19812-1.321.321", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.321.321", "start_pos": 321, "end_pos": 321, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "The E2-E3 interaction in the N-end rule pathway: the RING-H2 finger of E3 is required for the synthesis of multiubiquitin chain.", "journal": "The EMBO journal", "date": "1999", "authors": "Xie Y, Varshavsky A", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "reference": [ { "type": "PubMed", "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257" } ] } ], "crossref": [ { "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "H", "start_aa": "H", "up_seq": "PSLAKIDPENYTVIIYNDEY", "down_seq": "NYSQATTALRQGVPDNVHID", "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "Y", "comment": "Abolished ability to degrade proteins with type-2 N-degrons without affecting ability to degrade proteins with type-1 N-degrons.", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "PubMed", "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P19812-1.302.302", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P19812-1.313.313", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P19812-1.318.318", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.406.406", "start_pos": 406, "end_pos": 406, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "The E2-E3 interaction in the N-end rule pathway: the RING-H2 finger of E3 is required for the synthesis of multiubiquitin chain.", "journal": "The EMBO journal", "date": "1999", "authors": "Xie Y, Varshavsky A", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "reference": [ { "type": "PubMed", "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257" } ] } ], "crossref": [ { "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "P", "start_aa": "P", "up_seq": "YLHQETCKYIILWITHCLNI", "down_seq": "NSSFQTTFRNMMGKTLCSEY", "mutagenesis": [ { "sequence_org": "P", "sequence_mut": "S", "comment": "Abolished ability to degrade proteins with type-2 N-degrons without affecting ability to degrade proteins with type-1 N-degrons.", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "PubMed", "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.560.560", "start_pos": 560, "end_pos": 560, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "The E2-E3 interaction in the N-end rule pathway: the RING-H2 finger of E3 is required for the synthesis of multiubiquitin chain.", "journal": "The EMBO journal", "date": "1999", "authors": "Xie Y, Varshavsky A", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "reference": [ { "type": "PubMed", "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257" } ] } ], "crossref": [ { "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "E", "start_aa": "E", "up_seq": "CQQVVEIFNHITRSVAYMDR", "down_seq": "PQLTAIRECVVQLFTCPTNA", "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "K", "comment": "Abolished ability to degrade proteins with type-2 N-degrons without affecting ability to degrade proteins with type-1 N-degrons.", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "PubMed", "id": "10581257", "url": "https://glygen.org/publication/PubMed/10581257" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.678.681", "start_pos": 678, "end_pos": 681, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Structural insights into Ubr1-mediated N-degron polyubiquitination.", "journal": "Nature", "date": "2021-12", "authors": "Pan Man, Zheng Qingyun, Wang Tian, Liang Lujun, Mao Junxiong, Zuo Chong, Ding Ruichao, Ai Huasong, Xie Yuan, Si Dong, Yu Yuanyuan, Liu Lei, Zhao Minglei", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "reference": [ { "type": "PubMed", "id": "34789879", "url": "https://glygen.org/publication/PubMed/34789879" } ] } ], "crossref": [ { "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "34789879", "url": "https://glygen.org/publication/PubMed/34789879", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "HVLH", "start_aa": "H", "up_seq": "LLTLCKLFNGAWKIKRKEGE", "down_seq": "EDQNFISYLEYTTSIYSIIQ", "mutagenesis": [ { "sequence_org": "HVLH", "sequence_mut": "AAAA", "comment": "In UBLM mutant; strongly reduced ubiquitination of substrates.", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "PubMed", "id": "34789879", "url": "https://glygen.org/publication/PubMed/34789879" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.933.933", "start_pos": 933, "end_pos": 933, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Structural insights into Ubr1-mediated N-degron polyubiquitination.", "journal": "Nature", "date": "2021-12", "authors": "Pan Man, Zheng Qingyun, Wang Tian, Liang Lujun, Mao Junxiong, Zuo Chong, Ding Ruichao, Ai Huasong, Xie Yuan, Si Dong, Yu Yuanyuan, Liu Lei, Zhao Minglei", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "reference": [ { "type": "PubMed", "id": "34789879", "url": "https://glygen.org/publication/PubMed/34789879" } ] } ], "crossref": [ { "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "34789879", "url": "https://glygen.org/publication/PubMed/34789879", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "RRMDQIKNSIIYNLYMKPLS", "down_seq": "SKLLRSVPDYLTEDTTEFDE", "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "In DHHY mutant; abolished E3 ubiquitin protein ligase activity; when associated with A-161, A-1175 and A-1763.", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "PubMed", "id": "34789879", "url": "https://glygen.org/publication/PubMed/34789879" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.1196.1196", "start_pos": 1196, "end_pos": 1196, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000003416", "url": "https://www.yeastgenome.org/locus/S000003416", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QARLLAKFNNQQTKFMKEHE", "down_seq": "EFDEQDNDVDMVGEKVYESE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003416", "url": "https://www.yeastgenome.org/locus/S000003416" }, { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1196" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P19812-1.1183.1183", "categories": [ "mutagenesis_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P19812-1.1186.1186", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P19812-1.1190.1190", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.1720.1720", "start_pos": 1720, "end_pos": 1720, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ], "crossref": [ { "id": "S000003416", "url": "https://www.yeastgenome.org/locus/S000003416", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "FKICLTCGVKVHLRADRHEM", "down_seq": "KHLNKNCFKPFGAFLMPNSS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003416", "url": "https://www.yeastgenome.org/locus/S000003416" }, { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ], "site_lbl": "Thr1720" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.1938.1938", "start_pos": 1938, "end_pos": 1938, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.", "journal": "Genes & development", "date": "2009-08-15", "authors": "Huber Alexandre, Bodenmiller Bernd, Uotila Aino, Stahl Michael, Wanka Stefanie, Gerrits Bertran, Aebersold Ruedi, Loewith Robbie", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000003416", "url": "https://www.yeastgenome.org/locus/S000003416", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QFDGATIIRNTNPRNLDEDD", "down_seq": "DDNDDSDEREIW", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000003416", "url": "https://www.yeastgenome.org/locus/S000003416" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1938" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "upstream", "id": "P19812-1.1944.1944", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.1944.1944", "start_pos": 1944, "end_pos": 1944, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.", "journal": "Genes & development", "date": "2009-08-15", "authors": "Huber Alexandre, Bodenmiller Bernd, Uotila Aino, Stahl Michael, Wanka Stefanie, Gerrits Bertran, Aebersold Ruedi, Loewith Robbie", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000003416", "url": "https://www.yeastgenome.org/locus/S000003416", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IIRNTNPRNLDEDDSDDNDD", "down_seq": "DEREIW", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "SGD", "id": "S000003416", "url": "https://www.yeastgenome.org/locus/S000003416" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1944" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "P19812-1.1938.1938", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.277.277", "start_pos": 277, "end_pos": 277, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Regulation of peptide import through phosphorylation of Ubr1, the ubiquitin ligase of the N-end rule pathway.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2008-12-09", "authors": "Hwang Cheol-Sang, Varshavsky Alexander", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "19033468", "url": "https://glygen.org/publication/PubMed/19033468" } ] } ], "crossref": [ { "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19033468", "url": "https://glygen.org/publication/PubMed/19033468", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000003416", "url": "https://www.yeastgenome.org/locus/S000003416", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "REMTQQGKMYERAQFLNDLK", "down_seq": "ENDYMFDGTTTAKTSPSNSP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P21965-1", "kinase_gene_name": "MCK1", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" }, { "database": "PubMed", "id": "19033468", "url": "https://glygen.org/publication/PubMed/19033468" } ], "site_lbl": "Tyr277" }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003416", "url": "https://www.yeastgenome.org/locus/S000003416" }, { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" }, { "database": "PubMed", "id": "19033468", "url": "https://glygen.org/publication/PubMed/19033468" } ], "site_lbl": "Tyr277" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "upstream", "id": "P19812-1.286.286", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P19812-1.288.288", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P19812-1.291.291", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P19812-1.292.292", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P19812-1.294.294", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P19812-1.296.296", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.286.286", "start_pos": 286, "end_pos": 286, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000003416", "url": "https://www.yeastgenome.org/locus/S000003416", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "YERAQFLNDLKYENDYMFDG", "down_seq": "TTAKTSPSNSPEASPSLAKI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003416", "url": "https://www.yeastgenome.org/locus/S000003416" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr286" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "P19812-1.277.277", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P19812-1.288.288", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P19812-1.291.291", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P19812-1.292.292", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P19812-1.294.294", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P19812-1.296.296", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P19812-1.300.300", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P19812-1.302.302", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.288.288", "start_pos": 288, "end_pos": 288, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Regulation of peptide import through phosphorylation of Ubr1, the ubiquitin ligase of the N-end rule pathway.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2008-12-09", "authors": "Hwang Cheol-Sang, Varshavsky Alexander", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "19033468", "url": "https://glygen.org/publication/PubMed/19033468" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19033468", "url": "https://glygen.org/publication/PubMed/19033468", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000003416", "url": "https://www.yeastgenome.org/locus/S000003416", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "RAQFLNDLKYENDYMFDGTT", "down_seq": "AKTSPSNSPEASPSLAKIDP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" }, { "database": "PubMed", "id": "19033468", "url": "https://glygen.org/publication/PubMed/19033468" }, { "database": "SGD", "id": "S000003416", "url": "https://www.yeastgenome.org/locus/S000003416" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr288" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P19812-1.277.277", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P19812-1.286.286", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P19812-1.291.291", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P19812-1.292.292", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P19812-1.294.294", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P19812-1.296.296", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P19812-1.300.300", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P19812-1.302.302", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.291.291", "start_pos": 291, "end_pos": 291, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "Journal of proteome research", "date": "2007-03", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast.", "journal": "Proteomics", "date": "2009-10", "authors": "Gnad Florian, de Godoy Lyris M F, Cox J\u00fcrgen, Neuhauser Nadin, Ren Shubin, Olsen Jesper V, Mann Matthias", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" } ] }, { "title": "Global analysis of the yeast osmotic stress response by quantitative proteomics.", "journal": "Molecular bioSystems", "date": "2009-11", "authors": "Soufi Boumediene, Kelstrup Christian D, Stoehr Gabriele, Fr\u00f6hlich Florian, Walther Tobias C, Olsen Jesper V", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] }, { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000003416", "url": "https://www.yeastgenome.org/locus/S000003416", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "FLNDLKYENDYMFDGTTTAK", "down_seq": "SPSNSPEASPSLAKIDPENY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000003416", "url": "https://www.yeastgenome.org/locus/S000003416" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr291" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "P19812-1.277.277", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P19812-1.286.286", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P19812-1.288.288", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P19812-1.292.292", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P19812-1.294.294", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P19812-1.296.296", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P19812-1.300.300", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P19812-1.302.302", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.292.292", "start_pos": 292, "end_pos": 292, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "Journal of proteome research", "date": "2007-03", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Regulation of peptide import through phosphorylation of Ubr1, the ubiquitin ligase of the N-end rule pathway.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2008-12-09", "authors": "Hwang Cheol-Sang, Varshavsky Alexander", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "19033468", "url": "https://glygen.org/publication/PubMed/19033468" } ] }, { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19033468", "url": "https://glygen.org/publication/PubMed/19033468", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000003416", "url": "https://www.yeastgenome.org/locus/S000003416", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LNDLKYENDYMFDGTTTAKT", "down_seq": "PSNSPEASPSLAKIDPENYT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19033468", "url": "https://glygen.org/publication/PubMed/19033468" }, { "database": "SGD", "id": "S000003416", "url": "https://www.yeastgenome.org/locus/S000003416" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser292" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P19812-1.277.277", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P19812-1.286.286", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P19812-1.288.288", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P19812-1.291.291", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P19812-1.294.294", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P19812-1.296.296", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P19812-1.300.300", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P19812-1.302.302", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 7 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.294.294", "start_pos": 294, "end_pos": 294, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000003416", "url": "https://www.yeastgenome.org/locus/S000003416", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DLKYENDYMFDGTTTAKTSP", "down_seq": "NSPEASPSLAKIDPENYTVI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003416", "url": "https://www.yeastgenome.org/locus/S000003416" }, { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser294" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P19812-1.277.277", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P19812-1.286.286", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P19812-1.288.288", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P19812-1.291.291", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P19812-1.292.292", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P19812-1.296.296", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P19812-1.300.300", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P19812-1.302.302", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P19812-1.313.313", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.296.296", "start_pos": 296, "end_pos": 296, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "Journal of proteome research", "date": "2007-03", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "Regulation of peptide import through phosphorylation of Ubr1, the ubiquitin ligase of the N-end rule pathway.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2008-12-09", "authors": "Hwang Cheol-Sang, Varshavsky Alexander", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "19033468", "url": "https://glygen.org/publication/PubMed/19033468" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19033468", "url": "https://glygen.org/publication/PubMed/19033468", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000003416", "url": "https://www.yeastgenome.org/locus/S000003416", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KYENDYMFDGTTTAKTSPSN", "down_seq": "PEASPSLAKIDPENYTVIIY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "19033468", "url": "https://glygen.org/publication/PubMed/19033468" }, { "database": "SGD", "id": "S000003416", "url": "https://www.yeastgenome.org/locus/S000003416" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser296" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P19812-1.277.277", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P19812-1.286.286", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P19812-1.288.288", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P19812-1.291.291", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P19812-1.292.292", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P19812-1.294.294", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P19812-1.300.300", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P19812-1.302.302", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P19812-1.313.313", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 9 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.2.2", "start_pos": 2, "end_pos": 2, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.", "journal": "Molecular & cellular proteomics : MCP", "date": "2005-03", "authors": "Gruhler Albrecht, Olsen Jesper V, Mohammed Shabaz, Mortensen Peter, Faergeman Nils J, Mann Matthias, Jensen Ole N", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000003416", "url": "https://www.yeastgenome.org/locus/S000003416", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "M", "down_seq": "VADDDLGSLQGHIRRTLRSI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "SGD", "id": "S000003416", "url": "https://www.yeastgenome.org/locus/S000003416" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser2" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.300.300", "start_pos": 300, "end_pos": 300, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Regulation of peptide import through phosphorylation of Ubr1, the ubiquitin ligase of the N-end rule pathway.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2008-12-09", "authors": "Hwang Cheol-Sang, Varshavsky Alexander", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "19033468", "url": "https://glygen.org/publication/PubMed/19033468" } ] }, { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "Journal of proteome research", "date": "2007-03", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19033468", "url": "https://glygen.org/publication/PubMed/19033468", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000003416", "url": "https://www.yeastgenome.org/locus/S000003416", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DYMFDGTTTAKTSPSNSPEA", "down_seq": "PSLAKIDPENYTVIIYNDEY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P23291-1", "kinase_gene_name": "YCK1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" }, { "database": "PubMed", "id": "19033468", "url": "https://glygen.org/publication/PubMed/19033468" } ], "site_lbl": "Ser300" }, { "kinase_uniprot_canonical_ac": "P23292-1", "kinase_gene_name": "YCK2", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" }, { "database": "PubMed", "id": "19033468", "url": "https://glygen.org/publication/PubMed/19033468" } ], "site_lbl": "Ser300" }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000003416", "url": "https://www.yeastgenome.org/locus/S000003416" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19033468", "url": "https://glygen.org/publication/PubMed/19033468" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser300" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "P19812-1.286.286", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P19812-1.288.288", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P19812-1.291.291", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P19812-1.292.292", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P19812-1.294.294", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P19812-1.296.296", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P19812-1.302.302", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P19812-1.313.313", "categories": [ "mutagenesis_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P19812-1.318.318", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 9 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.302.302", "start_pos": 302, "end_pos": 302, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" }, { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000003416", "url": "https://www.yeastgenome.org/locus/S000003416", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MFDGTTTAKTSPSNSPEASP", "down_seq": "LAKIDPENYTVIIYNDEYHN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000003416", "url": "https://www.yeastgenome.org/locus/S000003416" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser302" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P19812-1.286.286", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P19812-1.288.288", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P19812-1.291.291", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P19812-1.292.292", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P19812-1.294.294", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P19812-1.296.296", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P19812-1.300.300", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P19812-1.313.313", "categories": [ "mutagenesis_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P19812-1.318.318", "categories": [ "mutagenesis_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P19812-1.321.321", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.492.492", "start_pos": 492, "end_pos": 492, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "crossref": [ { "id": "S000003416", "url": "https://www.yeastgenome.org/locus/S000003416", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "HKILPESSTHSLSPLINDVE", "down_seq": "PTSRTYSNTRLQHILYFDNR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003416", "url": "https://www.yeastgenome.org/locus/S000003416" }, { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Thr492" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19812-1.743.743", "start_pos": 743, "end_pos": 743, "uniprot_canonical_ac": "P19812-1", "length": 1950, "uniprot_id": "UBR1_YEAST", "protein_name": "E3 ubiquitin-protein ligase UBR1", "refseq_ac": "NP_011700", "refseq_name": "E3 ubiquitin-protein ligase UBR1", "gene_name": "UBR1", "gene_names_uniprotkb": "UBR1; G7168; PTR1", "gene_names_refseq": "PTR1; UBR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19812", "url": "https://www.uniprot.org/uniprotkb/P19812" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000003416", "url": "https://www.yeastgenome.org/locus/S000003416", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IRIISSFLGNRSLTYKLIYD", "down_seq": "HEVIKFSVSHERVAFMNPLQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003416", "url": "https://www.yeastgenome.org/locus/S000003416" }, { "database": "iPTMnet", "id": "P19812", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19812" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser743" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1168", "end_pos": "1168" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "1173", "end_pos": "1173" }, { "start_pos": "1175", "end_pos": "1175" }, { "start_pos": "1183", "end_pos": "1183" }, { "start_pos": "1186", "end_pos": "1186" }, { "start_pos": "1190", "end_pos": "1190" }, { "start_pos": "1220", "end_pos": "1220" }, { "start_pos": "1223", "end_pos": "1223" }, { "start_pos": "1295", "end_pos": "1295" }, { "start_pos": "1297", "end_pos": "1297" }, { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "145", "end_pos": "146" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "1763", "end_pos": "1763" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "560", "end_pos": "560" }, { "start_pos": "678", "end_pos": "681" }, { "start_pos": "933", "end_pos": "933" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1196", "end_pos": "1196" }, { "start_pos": "1720", "end_pos": "1720" }, { "start_pos": "1938", "end_pos": "1938" }, { "start_pos": "1944", "end_pos": "1944" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "286", "end_pos": "286" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "492", "end_pos": "492" }, { "start_pos": "743", "end_pos": "743" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19882-1.100.100", "start_pos": 100, "end_pos": 100, "uniprot_canonical_ac": "P19882-1", "length": 572, "uniprot_id": "HSP60_YEAST", "protein_name": "Heat shock protein 60, mitochondrial", "refseq_ac": "NP_013360", "refseq_name": "chaperone ATPase HSP60", "gene_name": "HSP60", "gene_names_uniprotkb": "HSP60; L8479.10; MIF4", "gene_names_refseq": "CPN60; HSP60; MIF4; MNA2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19882", "url": "https://www.uniprot.org/uniprotkb/P19882" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SIVLKDKFENMGAKLLQEVA", "down_seq": "KTNEAAGDGTTSATVLGRAI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249" }, { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser100" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "102", "end_pos": "102" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "250", "end_pos": "250" }, { "start_pos": "373", "end_pos": "373" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "495", "end_pos": "495" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P19882-1.102.102", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19882-1.102.102", "start_pos": 102, "end_pos": 102, "uniprot_canonical_ac": "P19882-1", "length": 572, "uniprot_id": "HSP60_YEAST", "protein_name": "Heat shock protein 60, mitochondrial", "refseq_ac": "NP_013360", "refseq_name": "chaperone ATPase HSP60", "gene_name": "HSP60", "gene_names_uniprotkb": "HSP60; L8479.10; MIF4", "gene_names_refseq": "CPN60; HSP60; MIF4; MNA2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19882", "url": "https://www.uniprot.org/uniprotkb/P19882" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase.", "journal": "Molecular & cellular proteomics : MCP", "date": "2007-11", "authors": "Reinders J\u00f6rg, Wagner Karina, Zahedi Rene P, Stojanovski Diana, Eyrich Beate, van der Laan Martin, Rehling Peter, Sickmann Albert, Pfanner Nikolaus, Meisinger Chris", "evidence": [ { "database": "UniProtKB", "id": "P19882", "url": "https://www.uniprot.org/uniprotkb/P19882" }, { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" } ], "reference": [ { "type": "PubMed", "id": "17761666", "url": "https://glygen.org/publication/PubMed/17761666" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P19882", "url": "https://www.uniprot.org/uniprotkb/P19882", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17761666", "url": "https://glygen.org/publication/PubMed/17761666", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "VLKDKFENMGAKLLQEVASK", "down_seq": "NEAAGDGTTSATVLGRAIFT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P19882", "url": "https://www.uniprot.org/uniprotkb/P19882" }, { "database": "PubMed", "id": "17761666", "url": "https://glygen.org/publication/PubMed/17761666" }, { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" }, { "database": "SGD", "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr102" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "102", "end_pos": "102" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "250", "end_pos": "250" }, { "start_pos": "373", "end_pos": "373" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "495", "end_pos": "495" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P19882-1.100.100", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P19882-1.122.122", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19882-1.122.122", "start_pos": 122, "end_pos": 122, "uniprot_canonical_ac": "P19882-1", "length": 572, "uniprot_id": "HSP60_YEAST", "protein_name": "Heat shock protein 60, mitochondrial", "refseq_ac": "NP_013360", "refseq_name": "chaperone ATPase HSP60", "gene_name": "HSP60", "gene_names_uniprotkb": "HSP60; L8479.10; MIF4", "gene_names_refseq": "CPN60; HSP60; MIF4; MNA2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19882", "url": "https://www.uniprot.org/uniprotkb/P19882" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "TNEAAGDGTTSATVLGRAIF", "down_seq": "ESVKNVAAGCNPMDLRRGSQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249" }, { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr122" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "102", "end_pos": "102" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "250", "end_pos": "250" }, { "start_pos": "373", "end_pos": "373" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "495", "end_pos": "495" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P19882-1.102.102", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P19882-1.141.141", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19882-1.141.141", "start_pos": 141, "end_pos": 141, "uniprot_canonical_ac": "P19882-1", "length": 572, "uniprot_id": "HSP60_YEAST", "protein_name": "Heat shock protein 60, mitochondrial", "refseq_ac": "NP_013360", "refseq_name": "chaperone ATPase HSP60", "gene_name": "HSP60", "gene_names_uniprotkb": "HSP60; L8479.10; MIF4", "gene_names_refseq": "CPN60; HSP60; MIF4; MNA2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19882", "url": "https://www.uniprot.org/uniprotkb/P19882" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FTESVKNVAAGCNPMDLRRG", "down_seq": "QVAVEKVIEFLSANKKEITT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249" }, { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser141" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "102", "end_pos": "102" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "250", "end_pos": "250" }, { "start_pos": "373", "end_pos": "373" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "495", "end_pos": "495" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P19882-1.122.122", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P19882-1.153.153", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19882-1.153.153", "start_pos": 153, "end_pos": 153, "uniprot_canonical_ac": "P19882-1", "length": 572, "uniprot_id": "HSP60_YEAST", "protein_name": "Heat shock protein 60, mitochondrial", "refseq_ac": "NP_013360", "refseq_name": "chaperone ATPase HSP60", "gene_name": "HSP60", "gene_names_uniprotkb": "HSP60; L8479.10; MIF4", "gene_names_refseq": "CPN60; HSP60; MIF4; MNA2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19882", "url": "https://www.uniprot.org/uniprotkb/P19882" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NPMDLRRGSQVAVEKVIEFL", "down_seq": "ANKKEITTSEEIAQVATISA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249" }, { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser153" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "102", "end_pos": "102" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "250", "end_pos": "250" }, { "start_pos": "373", "end_pos": "373" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "495", "end_pos": "495" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P19882-1.141.141", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19882-1.185.185", "start_pos": 185, "end_pos": 185, "uniprot_canonical_ac": "P19882-1", "length": 572, "uniprot_id": "HSP60_YEAST", "protein_name": "Heat shock protein 60, mitochondrial", "refseq_ac": "NP_013360", "refseq_name": "chaperone ATPase HSP60", "gene_name": "HSP60", "gene_names_uniprotkb": "HSP60; L8479.10; MIF4", "gene_names_refseq": "CPN60; HSP60; MIF4; MNA2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19882", "url": "https://www.uniprot.org/uniprotkb/P19882" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IAQVATISANGDSHVGKLLA", "down_seq": "AMEKVGKEGVITIREGRTLE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249" }, { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser185" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "102", "end_pos": "102" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "250", "end_pos": "250" }, { "start_pos": "373", "end_pos": "373" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "495", "end_pos": "495" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "upstream", "id": "P19882-1.197.197", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19882-1.197.197", "start_pos": 197, "end_pos": 197, "uniprot_canonical_ac": "P19882-1", "length": 572, "uniprot_id": "HSP60_YEAST", "protein_name": "Heat shock protein 60, mitochondrial", "refseq_ac": "NP_013360", "refseq_name": "chaperone ATPase HSP60", "gene_name": "HSP60", "gene_names_uniprotkb": "HSP60; L8479.10; MIF4", "gene_names_refseq": "CPN60; HSP60; MIF4; MNA2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19882", "url": "https://www.uniprot.org/uniprotkb/P19882" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SHVGKLLASAMEKVGKEGVI", "down_seq": "IREGRTLEDELEVTEGMRFD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249" }, { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr197" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "102", "end_pos": "102" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "250", "end_pos": "250" }, { "start_pos": "373", "end_pos": "373" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "495", "end_pos": "495" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P19882-1.185.185", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19882-1.22.22", "start_pos": 22, "end_pos": 22, "uniprot_canonical_ac": "P19882-1", "length": 572, "uniprot_id": "HSP60_YEAST", "protein_name": "Heat shock protein 60, mitochondrial", "refseq_ac": "NP_013360", "refseq_name": "chaperone ATPase HSP60", "gene_name": "HSP60", "gene_names_uniprotkb": "HSP60; L8479.10; MIF4", "gene_names_refseq": "CPN60; HSP60; MIF4; MNA2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19882", "url": "https://www.uniprot.org/uniprotkb/P19882" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LRSSVVRSRATLRPLLRRAY", "down_seq": "SHKELKFGVEGRASLLKGVE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249" }, { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser22" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "102", "end_pos": "102" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "250", "end_pos": "250" }, { "start_pos": "373", "end_pos": "373" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "495", "end_pos": "495" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "P19882-1.23.23", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19882-1.232.232", "start_pos": 232, "end_pos": 232, "uniprot_canonical_ac": "P19882-1", "length": 572, "uniprot_id": "HSP60_YEAST", "protein_name": "Heat shock protein 60, mitochondrial", "refseq_ac": "NP_013360", "refseq_name": "chaperone ATPase HSP60", "gene_name": "HSP60", "gene_names_uniprotkb": "HSP60; L8479.10; MIF4", "gene_names_refseq": "CPN60; HSP60; MIF4; MNA2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19882", "url": "https://www.uniprot.org/uniprotkb/P19882" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EGMRFDRGFISPYFITDPKS", "down_seq": "KVEFEKPLLLLSEKKISSIQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249" }, { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser232" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "102", "end_pos": "102" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "250", "end_pos": "250" }, { "start_pos": "373", "end_pos": "373" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "495", "end_pos": "495" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "upstream", "id": "P19882-1.249.249", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P19882-1.250.250", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19882-1.23.23", "start_pos": 23, "end_pos": 23, "uniprot_canonical_ac": "P19882-1", "length": 572, "uniprot_id": "HSP60_YEAST", "protein_name": "Heat shock protein 60, mitochondrial", "refseq_ac": "NP_013360", "refseq_name": "chaperone ATPase HSP60", "gene_name": "HSP60", "gene_names_uniprotkb": "HSP60; L8479.10; MIF4", "gene_names_refseq": "CPN60; HSP60; MIF4; MNA2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19882", "url": "https://www.uniprot.org/uniprotkb/P19882" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RSSVVRSRATLRPLLRRAYS", "down_seq": "HKELKFGVEGRASLLKGVET", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249" }, { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser23" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "102", "end_pos": "102" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "250", "end_pos": "250" }, { "start_pos": "373", "end_pos": "373" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "495", "end_pos": "495" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "P19882-1.22.22", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19882-1.249.249", "start_pos": 249, "end_pos": 249, "uniprot_canonical_ac": "P19882-1", "length": 572, "uniprot_id": "HSP60_YEAST", "protein_name": "Heat shock protein 60, mitochondrial", "refseq_ac": "NP_013360", "refseq_name": "chaperone ATPase HSP60", "gene_name": "HSP60", "gene_names_uniprotkb": "HSP60; L8479.10; MIF4", "gene_names_refseq": "CPN60; HSP60; MIF4; MNA2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19882", "url": "https://www.uniprot.org/uniprotkb/P19882" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PKSSKVEFEKPLLLLSEKKI", "down_seq": "SIQDILPALEISNQSRRPLL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249" }, { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser249" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "102", "end_pos": "102" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "250", "end_pos": "250" }, { "start_pos": "373", "end_pos": "373" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "495", "end_pos": "495" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P19882-1.232.232", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P19882-1.250.250", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19882-1.250.250", "start_pos": 250, "end_pos": 250, "uniprot_canonical_ac": "P19882-1", "length": 572, "uniprot_id": "HSP60_YEAST", "protein_name": "Heat shock protein 60, mitochondrial", "refseq_ac": "NP_013360", "refseq_name": "chaperone ATPase HSP60", "gene_name": "HSP60", "gene_names_uniprotkb": "HSP60; L8479.10; MIF4", "gene_names_refseq": "CPN60; HSP60; MIF4; MNA2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19882", "url": "https://www.uniprot.org/uniprotkb/P19882" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KSSKVEFEKPLLLLSEKKIS", "down_seq": "IQDILPALEISNQSRRPLLI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249" }, { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser250" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "102", "end_pos": "102" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "250", "end_pos": "250" }, { "start_pos": "373", "end_pos": "373" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "495", "end_pos": "495" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P19882-1.232.232", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P19882-1.249.249", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19882-1.373.373", "start_pos": 373, "end_pos": 373, "uniprot_canonical_ac": "P19882-1", "length": 572, "uniprot_id": "HSP60_YEAST", "protein_name": "Heat shock protein 60, mitochondrial", "refseq_ac": "NP_013360", "refseq_name": "chaperone ATPase HSP60", "gene_name": "HSP60", "gene_names_uniprotkb": "HSP60; L8479.10; MIF4", "gene_names_refseq": "CPN60; HSP60; MIF4; MNA2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19882", "url": "https://www.uniprot.org/uniprotkb/P19882" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ILNGSGPKEAIQERIEQIKG", "down_seq": "IDITTTNSYEKEKLQERLAK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser373" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "102", "end_pos": "102" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "250", "end_pos": "250" }, { "start_pos": "373", "end_pos": "373" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "495", "end_pos": "495" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "upstream", "id": "P19882-1.378.378", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P19882-1.381.381", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19882-1.378.378", "start_pos": 378, "end_pos": 378, "uniprot_canonical_ac": "P19882-1", "length": 572, "uniprot_id": "HSP60_YEAST", "protein_name": "Heat shock protein 60, mitochondrial", "refseq_ac": "NP_013360", "refseq_name": "chaperone ATPase HSP60", "gene_name": "HSP60", "gene_names_uniprotkb": "HSP60; L8479.10; MIF4", "gene_names_refseq": "CPN60; HSP60; MIF4; MNA2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19882", "url": "https://www.uniprot.org/uniprotkb/P19882" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "GPKEAIQERIEQIKGSIDIT", "down_seq": "TNSYEKEKLQERLAKLSGGV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249" }, { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr378" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "102", "end_pos": "102" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "250", "end_pos": "250" }, { "start_pos": "373", "end_pos": "373" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "495", "end_pos": "495" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "P19882-1.373.373", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P19882-1.381.381", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P19882-1.395.395", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19882-1.381.381", "start_pos": 381, "end_pos": 381, "uniprot_canonical_ac": "P19882-1", "length": 572, "uniprot_id": "HSP60_YEAST", "protein_name": "Heat shock protein 60, mitochondrial", "refseq_ac": "NP_013360", "refseq_name": "chaperone ATPase HSP60", "gene_name": "HSP60", "gene_names_uniprotkb": "HSP60; L8479.10; MIF4", "gene_names_refseq": "CPN60; HSP60; MIF4; MNA2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19882", "url": "https://www.uniprot.org/uniprotkb/P19882" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EAIQERIEQIKGSIDITTTN", "down_seq": "YEKEKLQERLAKLSGGVAVI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249" }, { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser381" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "102", "end_pos": "102" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "250", "end_pos": "250" }, { "start_pos": "373", "end_pos": "373" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "495", "end_pos": "495" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "P19882-1.373.373", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P19882-1.378.378", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P19882-1.395.395", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19882-1.395.395", "start_pos": 395, "end_pos": 395, "uniprot_canonical_ac": "P19882-1", "length": 572, "uniprot_id": "HSP60_YEAST", "protein_name": "Heat shock protein 60, mitochondrial", "refseq_ac": "NP_013360", "refseq_name": "chaperone ATPase HSP60", "gene_name": "HSP60", "gene_names_uniprotkb": "HSP60; L8479.10; MIF4", "gene_names_refseq": "CPN60; HSP60; MIF4; MNA2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19882", "url": "https://www.uniprot.org/uniprotkb/P19882" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DITTTNSYEKEKLQERLAKL", "down_seq": "GGVAVIRVGGASEVEVGEKK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser395" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "102", "end_pos": "102" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "250", "end_pos": "250" }, { "start_pos": "373", "end_pos": "373" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "495", "end_pos": "495" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P19882-1.378.378", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P19882-1.381.381", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P19882-1.407.407", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19882-1.407.407", "start_pos": 407, "end_pos": 407, "uniprot_canonical_ac": "P19882-1", "length": 572, "uniprot_id": "HSP60_YEAST", "protein_name": "Heat shock protein 60, mitochondrial", "refseq_ac": "NP_013360", "refseq_name": "chaperone ATPase HSP60", "gene_name": "HSP60", "gene_names_uniprotkb": "HSP60; L8479.10; MIF4", "gene_names_refseq": "CPN60; HSP60; MIF4; MNA2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19882", "url": "https://www.uniprot.org/uniprotkb/P19882" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LQERLAKLSGGVAVIRVGGA", "down_seq": "EVEVGEKKDRYDDALNATRA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249" }, { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser407" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "102", "end_pos": "102" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "250", "end_pos": "250" }, { "start_pos": "373", "end_pos": "373" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "495", "end_pos": "495" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P19882-1.395.395", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19882-1.485.485", "start_pos": 485, "end_pos": 485, "uniprot_canonical_ac": "P19882-1", "length": 572, "uniprot_id": "HSP60_YEAST", "protein_name": "Heat shock protein 60, mitochondrial", "refseq_ac": "NP_013360", "refseq_name": "chaperone ATPase HSP60", "gene_name": "HSP60", "gene_names_uniprotkb": "HSP60; L8479.10; MIF4", "gene_names_refseq": "CPN60; HSP60; MIF4; MNA2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19882", "url": "https://www.uniprot.org/uniprotkb/P19882" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P19882", "url": "https://www.uniprot.org/uniprotkb/P19882" }, { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P19882", "url": "https://www.uniprot.org/uniprotkb/P19882", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IRKAITRPAKQIIENAGEEG", "down_seq": "VIIGKLIDEYGDDFAKGYDA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P19882", "url": "https://www.uniprot.org/uniprotkb/P19882" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser485" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "102", "end_pos": "102" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "250", "end_pos": "250" }, { "start_pos": "373", "end_pos": "373" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "495", "end_pos": "495" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "upstream", "id": "P19882-1.495.495", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P19882-1.495.495", "start_pos": 495, "end_pos": 495, "uniprot_canonical_ac": "P19882-1", "length": 572, "uniprot_id": "HSP60_YEAST", "protein_name": "Heat shock protein 60, mitochondrial", "refseq_ac": "NP_013360", "refseq_name": "chaperone ATPase HSP60", "gene_name": "HSP60", "gene_names_uniprotkb": "HSP60; L8479.10; MIF4", "gene_names_refseq": "CPN60; HSP60; MIF4; MNA2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P19882", "url": "https://www.uniprot.org/uniprotkb/P19882" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "QIIENAGEEGSVIIGKLIDE", "down_seq": "GDDFAKGYDASKSEYTDMLA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004249", "url": "https://www.yeastgenome.org/locus/S000004249" }, { "database": "iPTMnet", "id": "P19882", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19882" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Tyr495" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "102", "end_pos": "102" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "250", "end_pos": "250" }, { "start_pos": "373", "end_pos": "373" }, { "start_pos": "378", "end_pos": "378" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "495", "end_pos": "495" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "P19882-1.485.485", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20434-1.158.158", "start_pos": 158, "end_pos": 158, "uniprot_canonical_ac": "P20434-1", "length": 215, "uniprot_id": "RPAB1_YEAST", "protein_name": "DNA-directed RNA polymerases I, II, and III subunit RPABC1", "refseq_ac": "NP_009712", "refseq_name": "DNA-directed RNA polymerase core subunit RPB5", "gene_name": "RPB5", "gene_names_uniprotkb": "RPB5; RPA7; RPC9; YBR1204", "gene_names_refseq": "RPB5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20434", "url": "https://www.uniprot.org/uniprotkb/P20434" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P20434", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20434" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000358", "url": "https://www.yeastgenome.org/locus/S000000358", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P20434", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20434", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AALVVNITHHELVPKHIRLS", "down_seq": "DEKRELLKRYRLKESQLPRI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000358", "url": "https://www.yeastgenome.org/locus/S000000358" }, { "database": "iPTMnet", "id": "P20434", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20434" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser158" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "158", "end_pos": "158" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20436-1.68.68", "start_pos": 68, "end_pos": 68, "uniprot_canonical_ac": "P20436-1", "length": 146, "uniprot_id": "RPAB3_YEAST", "protein_name": "DNA-directed RNA polymerases I, II, and III subunit RPABC3", "refseq_ac": "NP_014867", "refseq_name": "DNA-directed RNA polymerase core subunit RPB8", "gene_name": "RPB8", "gene_names_uniprotkb": "RPB8; YOR50-14", "gene_names_refseq": "RPB8", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20436", "url": "https://www.uniprot.org/uniprotkb/P20436" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P20436", "url": "https://www.uniprot.org/uniprotkb/P20436" }, { "database": "iPTMnet", "id": "P20436", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20436" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Effects of Acetylation and Phosphorylation on Subunit Interactions in Three Large Eukaryotic Complexes.", "journal": "Molecular & cellular proteomics : MCP", "date": "2018-12", "authors": "\u0160o\u0161tari\u0107 Nikolina, O'Reilly Francis J, Giansanti Piero, Heck Albert J R, Gavin Anne-Claude, van Noort Vera", "evidence": [ { "database": "iPTMnet", "id": "P20436", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20436" } ], "reference": [ { "type": "PubMed", "id": "30181345", "url": "https://glygen.org/publication/PubMed/30181345" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P20436", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20436" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P20436", "url": "https://www.uniprot.org/uniprotkb/P20436", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P20436", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20436", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000005750", "url": "https://www.yeastgenome.org/locus/S000005750", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "30181345", "url": "https://glygen.org/publication/PubMed/30181345", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PVAAQDSLTVTIASSLNLED", "down_seq": "PANDSSATRSWRPPQAGDRS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P20436", "url": "https://www.uniprot.org/uniprotkb/P20436" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P20436", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20436" }, { "database": "SGD", "id": "S000005750", "url": "https://www.yeastgenome.org/locus/S000005750" }, { "database": "PubMed", "id": "30181345", "url": "https://glygen.org/publication/PubMed/30181345" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr68" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "68", "end_pos": "68" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "78", "end_pos": "78" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "upstream", "id": "P20436-1.73.73", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P20436-1.74.74", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P20436-1.78.78", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20436-1.73.73", "start_pos": 73, "end_pos": 73, "uniprot_canonical_ac": "P20436-1", "length": 146, "uniprot_id": "RPAB3_YEAST", "protein_name": "DNA-directed RNA polymerases I, II, and III subunit RPABC3", "refseq_ac": "NP_014867", "refseq_name": "DNA-directed RNA polymerase core subunit RPB8", "gene_name": "RPB8", "gene_names_uniprotkb": "RPB8; YOR50-14", "gene_names_refseq": "RPB8", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20436", "url": "https://www.uniprot.org/uniprotkb/P20436" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P20436", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20436" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005750", "url": "https://www.yeastgenome.org/locus/S000005750", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P20436", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20436", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DSLTVTIASSLNLEDTPAND", "down_seq": "SATRSWRPPQAGDRSLADDY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005750", "url": "https://www.yeastgenome.org/locus/S000005750" }, { "database": "iPTMnet", "id": "P20436", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20436" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser73" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "68", "end_pos": "68" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "78", "end_pos": "78" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "P20436-1.68.68", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P20436-1.74.74", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P20436-1.78.78", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20436-1.74.74", "start_pos": 74, "end_pos": 74, "uniprot_canonical_ac": "P20436-1", "length": 146, "uniprot_id": "RPAB3_YEAST", "protein_name": "DNA-directed RNA polymerases I, II, and III subunit RPABC3", "refseq_ac": "NP_014867", "refseq_name": "DNA-directed RNA polymerase core subunit RPB8", "gene_name": "RPB8", "gene_names_uniprotkb": "RPB8; YOR50-14", "gene_names_refseq": "RPB8", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20436", "url": "https://www.uniprot.org/uniprotkb/P20436" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P20436", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20436" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005750", "url": "https://www.yeastgenome.org/locus/S000005750", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P20436", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20436", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SLTVTIASSLNLEDTPANDS", "down_seq": "ATRSWRPPQAGDRSLADDYD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005750", "url": "https://www.yeastgenome.org/locus/S000005750" }, { "database": "iPTMnet", "id": "P20436", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20436" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser74" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "68", "end_pos": "68" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "78", "end_pos": "78" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "P20436-1.68.68", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P20436-1.73.73", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P20436-1.78.78", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20436-1.78.78", "start_pos": 78, "end_pos": 78, "uniprot_canonical_ac": "P20436-1", "length": 146, "uniprot_id": "RPAB3_YEAST", "protein_name": "DNA-directed RNA polymerases I, II, and III subunit RPABC3", "refseq_ac": "NP_014867", "refseq_name": "DNA-directed RNA polymerase core subunit RPB8", "gene_name": "RPB8", "gene_names_uniprotkb": "RPB8; YOR50-14", "gene_names_refseq": "RPB8", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20436", "url": "https://www.uniprot.org/uniprotkb/P20436" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P20436", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20436" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005750", "url": "https://www.yeastgenome.org/locus/S000005750", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P20436", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20436", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TIASSLNLEDTPANDSSATR", "down_seq": "WRPPQAGDRSLADDYDYVMY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005750", "url": "https://www.yeastgenome.org/locus/S000005750" }, { "database": "iPTMnet", "id": "P20436", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20436" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser78" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "68", "end_pos": "68" }, { "start_pos": "73", "end_pos": "73" }, { "start_pos": "74", "end_pos": "74" }, { "start_pos": "78", "end_pos": "78" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "P20436-1.68.68", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P20436-1.73.73", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P20436-1.74.74", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20437-1.448.448", "start_pos": 448, "end_pos": 448, "uniprot_canonical_ac": "P20437-1", "length": 546, "uniprot_id": "CG11_YEAST", "protein_name": "G1/S-specific cyclin CLN1", "refseq_ac": "NP_013926", "refseq_name": "cyclin CLN1", "gene_name": "CLN1", "gene_names_uniprotkb": "CLN1; YM9646.13", "gene_names_refseq": "CLN1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20437", "url": "https://www.uniprot.org/uniprotkb/P20437" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "GLY_001160", "url": "https://data.glygen.org/GLY_001160", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "S000004812", "url": "https://www.yeastgenome.org/locus/S000004812", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SAQSDNSVFSTTNIDHSSPI", "down_seq": "PHMYTFNQFKNESACDSAIS", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr448", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004812", "url": "https://www.yeastgenome.org/locus/S000004812" }, { "database": "iPTMnet", "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr448" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "448", "end_pos": "448" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "448", "end_pos": "448" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "506", "end_pos": "506" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "535", "end_pos": "535" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P20437-1.445.445", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20437-1.105.105", "start_pos": 105, "end_pos": 105, "uniprot_canonical_ac": "P20437-1", "length": 546, "uniprot_id": "CG11_YEAST", "protein_name": "G1/S-specific cyclin CLN1", "refseq_ac": "NP_013926", "refseq_name": "cyclin CLN1", "gene_name": "CLN1", "gene_names_uniprotkb": "CLN1; YM9646.13", "gene_names_refseq": "CLN1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20437", "url": "https://www.uniprot.org/uniprotkb/P20437" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004812", "url": "https://www.yeastgenome.org/locus/S000004812", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MTRVSNGIFFHAVRFYDRYC", "down_seq": "KRVVLKDQAKLVVGTCLWLA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004812", "url": "https://www.yeastgenome.org/locus/S000004812" }, { "database": "iPTMnet", "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser105" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "448", "end_pos": "448" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "448", "end_pos": "448" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "506", "end_pos": "506" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "535", "end_pos": "535" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20437-1.252.252", "start_pos": 252, "end_pos": 252, "uniprot_canonical_ac": "P20437-1", "length": 546, "uniprot_id": "CG11_YEAST", "protein_name": "G1/S-specific cyclin CLN1", "refseq_ac": "NP_013926", "refseq_name": "cyclin CLN1", "gene_name": "CLN1", "gene_names_uniprotkb": "CLN1; YM9646.13", "gene_names_refseq": "CLN1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20437", "url": "https://www.uniprot.org/uniprotkb/P20437" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] } ], "crossref": [ { "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004812", "url": "https://www.yeastgenome.org/locus/S000004812", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KRKSQSSDDSDATVEEHISS", "down_seq": "PQSTGLDGDTTTMDEDEELN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000004812", "url": "https://www.yeastgenome.org/locus/S000004812" } ], "site_lbl": "Ser252" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "448", "end_pos": "448" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "448", "end_pos": "448" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "506", "end_pos": "506" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "535", "end_pos": "535" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "P20437-1.255.255", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20437-1.255.255", "start_pos": 255, "end_pos": 255, "uniprot_canonical_ac": "P20437-1", "length": 546, "uniprot_id": "CG11_YEAST", "protein_name": "G1/S-specific cyclin CLN1", "refseq_ac": "NP_013926", "refseq_name": "cyclin CLN1", "gene_name": "CLN1", "gene_names_uniprotkb": "CLN1; YM9646.13", "gene_names_refseq": "CLN1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20437", "url": "https://www.uniprot.org/uniprotkb/P20437" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] } ], "crossref": [ { "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004812", "url": "https://www.yeastgenome.org/locus/S000004812", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SQSSDDSDATVEEHISSSPQ", "down_seq": "TGLDGDTTTMDEDEELNSKI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000004812", "url": "https://www.yeastgenome.org/locus/S000004812" } ], "site_lbl": "Ser255" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "448", "end_pos": "448" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "448", "end_pos": "448" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "506", "end_pos": "506" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "535", "end_pos": "535" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P20437-1.252.252", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20437-1.385.385", "start_pos": 385, "end_pos": 385, "uniprot_canonical_ac": "P20437-1", "length": 546, "uniprot_id": "CG11_YEAST", "protein_name": "G1/S-specific cyclin CLN1", "refseq_ac": "NP_013926", "refseq_name": "cyclin CLN1", "gene_name": "CLN1", "gene_names_uniprotkb": "CLN1; YM9646.13", "gene_names_refseq": "CLN1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20437", "url": "https://www.uniprot.org/uniprotkb/P20437" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000004812", "url": "https://www.yeastgenome.org/locus/S000004812", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PFILQVKDYNLELQKKLQLA", "down_seq": "TIDLTRKIAVNSRYFDQNAS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004812", "url": "https://www.yeastgenome.org/locus/S000004812" }, { "database": "iPTMnet", "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser385" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "448", "end_pos": "448" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "448", "end_pos": "448" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "506", "end_pos": "506" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "535", "end_pos": "535" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20437-1.411.411", "start_pos": 411, "end_pos": 411, "uniprot_canonical_ac": "P20437-1", "length": 546, "uniprot_id": "CG11_YEAST", "protein_name": "G1/S-specific cyclin CLN1", "refseq_ac": "NP_013926", "refseq_name": "cyclin CLN1", "gene_name": "CLN1", "gene_names_uniprotkb": "CLN1; YM9646.13", "gene_names_refseq": "CLN1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20437", "url": "https://www.uniprot.org/uniprotkb/P20437" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] } ], "crossref": [ { "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004812", "url": "https://www.yeastgenome.org/locus/S000004812", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RKIAVNSRYFDQNASSSSVS", "down_seq": "PSTYSSGTNYTPMRNFSAQS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000004812", "url": "https://www.yeastgenome.org/locus/S000004812" } ], "site_lbl": "Ser411" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "448", "end_pos": "448" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "448", "end_pos": "448" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "506", "end_pos": "506" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "535", "end_pos": "535" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20437-1.445.445", "start_pos": 445, "end_pos": 445, "uniprot_canonical_ac": "P20437-1", "length": 546, "uniprot_id": "CG11_YEAST", "protein_name": "G1/S-specific cyclin CLN1", "refseq_ac": "NP_013926", "refseq_name": "cyclin CLN1", "gene_name": "CLN1", "gene_names_uniprotkb": "CLN1; YM9646.13", "gene_names_refseq": "CLN1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20437", "url": "https://www.uniprot.org/uniprotkb/P20437" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004812", "url": "https://www.yeastgenome.org/locus/S000004812", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RNFSAQSDNSVFSTTNIDHS", "down_seq": "PITPHMYTFNQFKNESACDS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004812", "url": "https://www.yeastgenome.org/locus/S000004812" }, { "database": "iPTMnet", "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser445" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "448", "end_pos": "448" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "448", "end_pos": "448" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "506", "end_pos": "506" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "535", "end_pos": "535" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "P20437-1.448.448", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20437-1.4.4", "start_pos": 4, "end_pos": 4, "uniprot_canonical_ac": "P20437-1", "length": 546, "uniprot_id": "CG11_YEAST", "protein_name": "G1/S-specific cyclin CLN1", "refseq_ac": "NP_013926", "refseq_name": "cyclin CLN1", "gene_name": "CLN1", "gene_names_uniprotkb": "CLN1; YM9646.13", "gene_names_refseq": "CLN1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20437", "url": "https://www.uniprot.org/uniprotkb/P20437" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004812", "url": "https://www.yeastgenome.org/locus/S000004812", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MNH", "down_seq": "EVKTGLIVTAKQTYYPIELS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004812", "url": "https://www.yeastgenome.org/locus/S000004812" }, { "database": "iPTMnet", "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser4" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "448", "end_pos": "448" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "448", "end_pos": "448" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "506", "end_pos": "506" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "535", "end_pos": "535" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20437-1.505.505", "start_pos": 505, "end_pos": 505, "uniprot_canonical_ac": "P20437-1", "length": 546, "uniprot_id": "CG11_YEAST", "protein_name": "G1/S-specific cyclin CLN1", "refseq_ac": "NP_013926", "refseq_name": "cyclin CLN1", "gene_name": "CLN1", "gene_names_uniprotkb": "CLN1; YM9646.13", "gene_names_refseq": "CLN1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20437", "url": "https://www.uniprot.org/uniprotkb/P20437" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004812", "url": "https://www.yeastgenome.org/locus/S000004812", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SNYQNMMLEERNKENRIPNS", "down_seq": "SAEIPQRAKFMTTGIFQNTG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004812", "url": "https://www.yeastgenome.org/locus/S000004812" }, { "database": "iPTMnet", "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser505" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "448", "end_pos": "448" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "448", "end_pos": "448" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "506", "end_pos": "506" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "535", "end_pos": "535" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "P20437-1.506.506", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20437-1.506.506", "start_pos": 506, "end_pos": 506, "uniprot_canonical_ac": "P20437-1", "length": 546, "uniprot_id": "CG11_YEAST", "protein_name": "G1/S-specific cyclin CLN1", "refseq_ac": "NP_013926", "refseq_name": "cyclin CLN1", "gene_name": "CLN1", "gene_names_uniprotkb": "CLN1; YM9646.13", "gene_names_refseq": "CLN1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20437", "url": "https://www.uniprot.org/uniprotkb/P20437" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast.", "journal": "Proteomics", "date": "2009-10", "authors": "Gnad Florian, de Godoy Lyris M F, Cox J\u00fcrgen, Neuhauser Nadin, Ren Shubin, Olsen Jesper V, Mann Matthias", "evidence": [ { "database": "iPTMnet", "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437" } ], "reference": [ { "type": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" } ] }, { "title": "Global analysis of the yeast osmotic stress response by quantitative proteomics.", "journal": "Molecular bioSystems", "date": "2009-11", "authors": "Soufi Boumediene, Kelstrup Christian D, Stoehr Gabriele, Fr\u00f6hlich Florian, Walther Tobias C, Olsen Jesper V", "evidence": [ { "database": "iPTMnet", "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437" } ], "reference": [ { "type": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004812", "url": "https://www.yeastgenome.org/locus/S000004812", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NYQNMMLEERNKENRIPNSS", "down_seq": "AEIPQRAKFMTTGIFQNTGE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000004812", "url": "https://www.yeastgenome.org/locus/S000004812" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser506" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "448", "end_pos": "448" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "448", "end_pos": "448" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "506", "end_pos": "506" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "535", "end_pos": "535" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "P20437-1.505.505", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20437-1.532.532", "start_pos": 532, "end_pos": 532, "uniprot_canonical_ac": "P20437-1", "length": 546, "uniprot_id": "CG11_YEAST", "protein_name": "G1/S-specific cyclin CLN1", "refseq_ac": "NP_013926", "refseq_name": "cyclin CLN1", "gene_name": "CLN1", "gene_names_uniprotkb": "CLN1; YM9646.13", "gene_names_refseq": "CLN1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20437", "url": "https://www.uniprot.org/uniprotkb/P20437" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000004812", "url": "https://www.yeastgenome.org/locus/S000004812", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RAKFMTTGIFQNTGELTNRA", "down_seq": "SISLSLRNHNSSQL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004812", "url": "https://www.yeastgenome.org/locus/S000004812" }, { "database": "iPTMnet", "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser532" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "448", "end_pos": "448" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "448", "end_pos": "448" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "506", "end_pos": "506" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "535", "end_pos": "535" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "P20437-1.533.533", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P20437-1.535.535", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20437-1.533.533", "start_pos": 533, "end_pos": 533, "uniprot_canonical_ac": "P20437-1", "length": 546, "uniprot_id": "CG11_YEAST", "protein_name": "G1/S-specific cyclin CLN1", "refseq_ac": "NP_013926", "refseq_name": "cyclin CLN1", "gene_name": "CLN1", "gene_names_uniprotkb": "CLN1; YM9646.13", "gene_names_refseq": "CLN1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20437", "url": "https://www.uniprot.org/uniprotkb/P20437" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "iPTMnet", "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] } ], "crossref": [ { "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004812", "url": "https://www.yeastgenome.org/locus/S000004812", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AKFMTTGIFQNTGELTNRAS", "down_seq": "ISLSLRNHNSSQL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004812", "url": "https://www.yeastgenome.org/locus/S000004812" } ], "site_lbl": "Ser533" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "448", "end_pos": "448" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "448", "end_pos": "448" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "506", "end_pos": "506" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "535", "end_pos": "535" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "P20437-1.532.532", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P20437-1.535.535", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20437-1.535.535", "start_pos": 535, "end_pos": 535, "uniprot_canonical_ac": "P20437-1", "length": 546, "uniprot_id": "CG11_YEAST", "protein_name": "G1/S-specific cyclin CLN1", "refseq_ac": "NP_013926", "refseq_name": "cyclin CLN1", "gene_name": "CLN1", "gene_names_uniprotkb": "CLN1; YM9646.13", "gene_names_refseq": "CLN1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20437", "url": "https://www.uniprot.org/uniprotkb/P20437" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004812", "url": "https://www.yeastgenome.org/locus/S000004812", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FMTTGIFQNTGELTNRASSI", "down_seq": "LSLRNHNSSQL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004812", "url": "https://www.yeastgenome.org/locus/S000004812" }, { "database": "iPTMnet", "id": "P20437", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20437" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser535" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "448", "end_pos": "448" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "448", "end_pos": "448" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "506", "end_pos": "506" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "535", "end_pos": "535" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P20437-1.532.532", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P20437-1.533.533", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20438-1.430.430", "start_pos": 430, "end_pos": 430, "uniprot_canonical_ac": "P20438-1", "length": 545, "uniprot_id": "CG12_YEAST", "protein_name": "G1/S-specific cyclin CLN2", "refseq_ac": "NP_015067", "refseq_name": "cyclin CLN2", "gene_name": "CLN2", "gene_names_uniprotkb": "CLN2", "gene_names_refseq": "CLN2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20438", "url": "https://www.uniprot.org/uniprotkb/P20438" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cdc53 targets phosphorylated G1 cyclins for degradation by the ubiquitin proteolytic pathway.", "journal": "Cell", "date": "1996-08-09", "authors": "Willems A R, Lanker S, Patton E E, Craig K L, Nason T F, Mathias N, Kobayashi R, Wittenberg C, Tyers M", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" } ], "reference": [ { "type": "PubMed", "id": "8756727", "url": "https://glygen.org/publication/PubMed/8756727" } ] } ], "crossref": [ { "id": "GLY_001160", "url": "https://data.glygen.org/GLY_001160", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "8756727", "url": "https://glygen.org/publication/PubMed/8756727", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "MSSLSDNSVFSRNMEQSSPI", "down_seq": "PSMYQFGQQQSNSICGSTVS", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr430", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" }, { "database": "PubMed", "id": "8756727", "url": "https://glygen.org/publication/PubMed/8756727" } ], "site_lbl": "Thr430" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "430", "end_pos": "430" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "233", "end_pos": "233" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "311", "end_pos": "311" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "417", "end_pos": "417" }, { "start_pos": "427", "end_pos": "427" }, { "start_pos": "430", "end_pos": "430" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "468", "end_pos": "468" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "518", "end_pos": "518" }, { "start_pos": "525", "end_pos": "525" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P20438-1.411.411", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "downstream", "id": "P20438-1.412.412", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P20438-1.414.414", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P20438-1.417.417", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P20438-1.427.427", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20438-1.233.233", "start_pos": 233, "end_pos": 233, "uniprot_canonical_ac": "P20438-1", "length": 545, "uniprot_id": "CG12_YEAST", "protein_name": "G1/S-specific cyclin CLN2", "refseq_ac": "NP_015067", "refseq_name": "cyclin CLN2", "gene_name": "CLN2", "gene_names_uniprotkb": "CLN2", "gene_names_refseq": "CLN2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20438", "url": "https://www.uniprot.org/uniprotkb/P20438" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] } ], "crossref": [ { "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000006177", "url": "https://www.yeastgenome.org/locus/S000006177", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QYELYENQVTYDKQCSEKRQ", "down_seq": "QLSQDSDATVDERPYQNEEE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000006177", "url": "https://www.yeastgenome.org/locus/S000006177" } ], "site_lbl": "Ser233" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "430", "end_pos": "430" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "233", "end_pos": "233" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "311", "end_pos": "311" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "417", "end_pos": "417" }, { "start_pos": "427", "end_pos": "427" }, { "start_pos": "430", "end_pos": "430" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "468", "end_pos": "468" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "518", "end_pos": "518" }, { "start_pos": "525", "end_pos": "525" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "P20438-1.236.236", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P20438-1.239.239", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20438-1.236.236", "start_pos": 236, "end_pos": 236, "uniprot_canonical_ac": "P20438-1", "length": 545, "uniprot_id": "CG12_YEAST", "protein_name": "G1/S-specific cyclin CLN2", "refseq_ac": "NP_015067", "refseq_name": "cyclin CLN2", "gene_name": "CLN2", "gene_names_uniprotkb": "CLN2", "gene_names_refseq": "CLN2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20438", "url": "https://www.uniprot.org/uniprotkb/P20438" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast.", "journal": "Proteomics", "date": "2009-10", "authors": "Gnad Florian, de Godoy Lyris M F, Cox J\u00fcrgen, Neuhauser Nadin, Ren Shubin, Olsen Jesper V, Mann Matthias", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" } ], "reference": [ { "type": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" } ] }, { "title": "Global analysis of the yeast osmotic stress response by quantitative proteomics.", "journal": "Molecular bioSystems", "date": "2009-11", "authors": "Soufi Boumediene, Kelstrup Christian D, Stoehr Gabriele, Fr\u00f6hlich Florian, Walther Tobias C, Olsen Jesper V", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" } ], "reference": [ { "type": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] }, { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] } ], "crossref": [ { "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000006177", "url": "https://www.yeastgenome.org/locus/S000006177", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LYENQVTYDKQCSEKRQSQL", "down_seq": "QDSDATVDERPYQNEEEEEE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000006177", "url": "https://www.yeastgenome.org/locus/S000006177" } ], "site_lbl": "Ser236" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "430", "end_pos": "430" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "233", "end_pos": "233" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "311", "end_pos": "311" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "417", "end_pos": "417" }, { "start_pos": "427", "end_pos": "427" }, { "start_pos": "430", "end_pos": "430" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "468", "end_pos": "468" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "518", "end_pos": "518" }, { "start_pos": "525", "end_pos": "525" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P20438-1.233.233", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P20438-1.239.239", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20438-1.239.239", "start_pos": 239, "end_pos": 239, "uniprot_canonical_ac": "P20438-1", "length": 545, "uniprot_id": "CG12_YEAST", "protein_name": "G1/S-specific cyclin CLN2", "refseq_ac": "NP_015067", "refseq_name": "cyclin CLN2", "gene_name": "CLN2", "gene_names_uniprotkb": "CLN2", "gene_names_refseq": "CLN2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20438", "url": "https://www.uniprot.org/uniprotkb/P20438" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast.", "journal": "Proteomics", "date": "2009-10", "authors": "Gnad Florian, de Godoy Lyris M F, Cox J\u00fcrgen, Neuhauser Nadin, Ren Shubin, Olsen Jesper V, Mann Matthias", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" } ], "reference": [ { "type": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" } ] }, { "title": "Global analysis of the yeast osmotic stress response by quantitative proteomics.", "journal": "Molecular bioSystems", "date": "2009-11", "authors": "Soufi Boumediene, Kelstrup Christian D, Stoehr Gabriele, Fr\u00f6hlich Florian, Walther Tobias C, Olsen Jesper V", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" } ], "reference": [ { "type": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000006177", "url": "https://www.yeastgenome.org/locus/S000006177", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NQVTYDKQCSEKRQSQLSQD", "down_seq": "DATVDERPYQNEEEEEEDLK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000006177", "url": "https://www.yeastgenome.org/locus/S000006177" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser239" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "430", "end_pos": "430" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "233", "end_pos": "233" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "311", "end_pos": "311" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "417", "end_pos": "417" }, { "start_pos": "427", "end_pos": "427" }, { "start_pos": "430", "end_pos": "430" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "468", "end_pos": "468" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "518", "end_pos": "518" }, { "start_pos": "525", "end_pos": "525" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "P20438-1.233.233", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P20438-1.236.236", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20438-1.311.311", "start_pos": 311, "end_pos": 311, "uniprot_canonical_ac": "P20438-1", "length": 545, "uniprot_id": "CG12_YEAST", "protein_name": "G1/S-specific cyclin CLN2", "refseq_ac": "NP_015067", "refseq_name": "cyclin CLN2", "gene_name": "CLN2", "gene_names_uniprotkb": "CLN2", "gene_names_refseq": "CLN2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20438", "url": "https://www.uniprot.org/uniprotkb/P20438" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cdc53 targets phosphorylated G1 cyclins for degradation by the ubiquitin proteolytic pathway.", "journal": "Cell", "date": "1996-08-09", "authors": "Willems A R, Lanker S, Patton E E, Craig K L, Nason T F, Mathias N, Kobayashi R, Wittenberg C, Tyers M", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" } ], "reference": [ { "type": "PubMed", "id": "8756727", "url": "https://glygen.org/publication/PubMed/8756727" } ] } ], "crossref": [ { "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "8756727", "url": "https://glygen.org/publication/PubMed/8756727", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "HGIFSIINQFTNQDHGPFLM", "down_seq": "PMTSESKNGEILSTLMNGIV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" }, { "database": "PubMed", "id": "8756727", "url": "https://glygen.org/publication/PubMed/8756727" } ], "site_lbl": "Thr311" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "430", "end_pos": "430" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "233", "end_pos": "233" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "311", "end_pos": "311" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "417", "end_pos": "417" }, { "start_pos": "427", "end_pos": "427" }, { "start_pos": "430", "end_pos": "430" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "468", "end_pos": "468" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "518", "end_pos": "518" }, { "start_pos": "525", "end_pos": "525" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20438-1.369.369", "start_pos": 369, "end_pos": 369, "uniprot_canonical_ac": "P20438-1", "length": 545, "uniprot_id": "CG12_YEAST", "protein_name": "G1/S-specific cyclin CLN2", "refseq_ac": "NP_015067", "refseq_name": "cyclin CLN2", "gene_name": "CLN2", "gene_names_uniprotkb": "CLN2", "gene_names_refseq": "CLN2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20438", "url": "https://www.uniprot.org/uniprotkb/P20438" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "crossref": [ { "id": "S000006177", "url": "https://www.yeastgenome.org/locus/S000006177", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PFINQVKEYHLDLQRKLQIA", "down_seq": "NLNISRKLTISTPSCSFENS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006177", "url": "https://www.yeastgenome.org/locus/S000006177" }, { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Ser369" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "430", "end_pos": "430" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "233", "end_pos": "233" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "311", "end_pos": "311" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "417", "end_pos": "417" }, { "start_pos": "427", "end_pos": "427" }, { "start_pos": "430", "end_pos": "430" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "468", "end_pos": "468" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "518", "end_pos": "518" }, { "start_pos": "525", "end_pos": "525" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "upstream", "id": "P20438-1.381.381", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20438-1.381.381", "start_pos": 381, "end_pos": 381, "uniprot_canonical_ac": "P20438-1", "length": 545, "uniprot_id": "CG12_YEAST", "protein_name": "G1/S-specific cyclin CLN2", "refseq_ac": "NP_015067", "refseq_name": "cyclin CLN2", "gene_name": "CLN2", "gene_names_uniprotkb": "CLN2", "gene_names_refseq": "CLN2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20438", "url": "https://www.uniprot.org/uniprotkb/P20438" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cdc53 targets phosphorylated G1 cyclins for degradation by the ubiquitin proteolytic pathway.", "journal": "Cell", "date": "1996-08-09", "authors": "Willems A R, Lanker S, Patton E E, Craig K L, Nason T F, Mathias N, Kobayashi R, Wittenberg C, Tyers M", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" } ], "reference": [ { "type": "PubMed", "id": "8756727", "url": "https://glygen.org/publication/PubMed/8756727" } ] } ], "crossref": [ { "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "8756727", "url": "https://glygen.org/publication/PubMed/8756727", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "LQRKLQIASNLNISRKLTIS", "down_seq": "PSCSFENSNSTSIPSPASSS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" }, { "database": "PubMed", "id": "8756727", "url": "https://glygen.org/publication/PubMed/8756727" } ], "site_lbl": "Thr381" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "430", "end_pos": "430" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "233", "end_pos": "233" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "311", "end_pos": "311" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "417", "end_pos": "417" }, { "start_pos": "427", "end_pos": "427" }, { "start_pos": "430", "end_pos": "430" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "468", "end_pos": "468" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "518", "end_pos": "518" }, { "start_pos": "525", "end_pos": "525" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P20438-1.369.369", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P20438-1.396.396", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20438-1.396.396", "start_pos": 396, "end_pos": 396, "uniprot_canonical_ac": "P20438-1", "length": 545, "uniprot_id": "CG12_YEAST", "protein_name": "G1/S-specific cyclin CLN2", "refseq_ac": "NP_015067", "refseq_name": "cyclin CLN2", "gene_name": "CLN2", "gene_names_uniprotkb": "CLN2", "gene_names_refseq": "CLN2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20438", "url": "https://www.uniprot.org/uniprotkb/P20438" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Rapid degradation of the G1 cyclin Cln2 induced by CDK-dependent phosphorylation.", "journal": "Science (New York, N.Y.)", "date": "1996-03-15", "authors": "Lanker S, Valdivieso M H, Wittenberg C", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" } ], "reference": [ { "type": "PubMed", "id": "8599119", "url": "https://glygen.org/publication/PubMed/8599119" } ] }, { "title": "Cdc53 targets phosphorylated G1 cyclins for degradation by the ubiquitin proteolytic pathway.", "journal": "Cell", "date": "1996-08-09", "authors": "Willems A R, Lanker S, Patton E E, Craig K L, Nason T F, Mathias N, Kobayashi R, Wittenberg C, Tyers M", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" } ], "reference": [ { "type": "PubMed", "id": "8756727", "url": "https://glygen.org/publication/PubMed/8756727" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "crossref": [ { "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "8599119", "url": "https://glygen.org/publication/PubMed/8599119", "database": "PubMed", "categories": [ "Other" ] }, { "id": "8756727", "url": "https://glygen.org/publication/PubMed/8756727", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000006177", "url": "https://www.yeastgenome.org/locus/S000006177", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KLTISTPSCSFENSNSTSIP", "down_seq": "PASSSQSHTPMRNMSSLSDN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" }, { "database": "PubMed", "id": "8599119", "url": "https://glygen.org/publication/PubMed/8599119" }, { "database": "PubMed", "id": "8756727", "url": "https://glygen.org/publication/PubMed/8756727" }, { "database": "SGD", "id": "S000006177", "url": "https://www.yeastgenome.org/locus/S000006177" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Ser396" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "430", "end_pos": "430" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "233", "end_pos": "233" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "311", "end_pos": "311" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "417", "end_pos": "417" }, { "start_pos": "427", "end_pos": "427" }, { "start_pos": "430", "end_pos": "430" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "468", "end_pos": "468" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "518", "end_pos": "518" }, { "start_pos": "525", "end_pos": "525" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P20438-1.381.381", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P20438-1.411.411", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P20438-1.412.412", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P20438-1.414.414", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20438-1.411.411", "start_pos": 411, "end_pos": 411, "uniprot_canonical_ac": "P20438-1", "length": 545, "uniprot_id": "CG12_YEAST", "protein_name": "G1/S-specific cyclin CLN2", "refseq_ac": "NP_015067", "refseq_name": "cyclin CLN2", "gene_name": "CLN2", "gene_names_uniprotkb": "CLN2", "gene_names_refseq": "CLN2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20438", "url": "https://www.uniprot.org/uniprotkb/P20438" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000006177", "url": "https://www.yeastgenome.org/locus/S000006177", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "STSIPSPASSSQSHTPMRNM", "down_seq": "SLSDNSVFSRNMEQSSPITP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006177", "url": "https://www.yeastgenome.org/locus/S000006177" }, { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser411" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "430", "end_pos": "430" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "233", "end_pos": "233" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "311", "end_pos": "311" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "417", "end_pos": "417" }, { "start_pos": "427", "end_pos": "427" }, { "start_pos": "430", "end_pos": "430" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "468", "end_pos": "468" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "518", "end_pos": "518" }, { "start_pos": "525", "end_pos": "525" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P20438-1.396.396", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P20438-1.412.412", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P20438-1.414.414", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P20438-1.417.417", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P20438-1.427.427", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P20438-1.430.430", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20438-1.412.412", "start_pos": 412, "end_pos": 412, "uniprot_canonical_ac": "P20438-1", "length": 545, "uniprot_id": "CG12_YEAST", "protein_name": "G1/S-specific cyclin CLN2", "refseq_ac": "NP_015067", "refseq_name": "cyclin CLN2", "gene_name": "CLN2", "gene_names_uniprotkb": "CLN2", "gene_names_refseq": "CLN2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20438", "url": "https://www.uniprot.org/uniprotkb/P20438" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006177", "url": "https://www.yeastgenome.org/locus/S000006177", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TSIPSPASSSQSHTPMRNMS", "down_seq": "LSDNSVFSRNMEQSSPITPS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006177", "url": "https://www.yeastgenome.org/locus/S000006177" }, { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser412" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "430", "end_pos": "430" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "233", "end_pos": "233" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "311", "end_pos": "311" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "417", "end_pos": "417" }, { "start_pos": "427", "end_pos": "427" }, { "start_pos": "430", "end_pos": "430" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "468", "end_pos": "468" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "518", "end_pos": "518" }, { "start_pos": "525", "end_pos": "525" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P20438-1.396.396", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P20438-1.411.411", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P20438-1.414.414", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P20438-1.417.417", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P20438-1.427.427", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P20438-1.430.430", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20438-1.414.414", "start_pos": 414, "end_pos": 414, "uniprot_canonical_ac": "P20438-1", "length": 545, "uniprot_id": "CG12_YEAST", "protein_name": "G1/S-specific cyclin CLN2", "refseq_ac": "NP_015067", "refseq_name": "cyclin CLN2", "gene_name": "CLN2", "gene_names_uniprotkb": "CLN2", "gene_names_refseq": "CLN2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20438", "url": "https://www.uniprot.org/uniprotkb/P20438" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006177", "url": "https://www.yeastgenome.org/locus/S000006177", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IPSPASSSQSHTPMRNMSSL", "down_seq": "DNSVFSRNMEQSSPITPSMY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006177", "url": "https://www.yeastgenome.org/locus/S000006177" }, { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser414" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "430", "end_pos": "430" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "233", "end_pos": "233" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "311", "end_pos": "311" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "417", "end_pos": "417" }, { "start_pos": "427", "end_pos": "427" }, { "start_pos": "430", "end_pos": "430" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "468", "end_pos": "468" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "518", "end_pos": "518" }, { "start_pos": "525", "end_pos": "525" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P20438-1.396.396", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P20438-1.411.411", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P20438-1.412.412", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P20438-1.417.417", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P20438-1.427.427", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P20438-1.430.430", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20438-1.417.417", "start_pos": 417, "end_pos": 417, "uniprot_canonical_ac": "P20438-1", "length": 545, "uniprot_id": "CG12_YEAST", "protein_name": "G1/S-specific cyclin CLN2", "refseq_ac": "NP_015067", "refseq_name": "cyclin CLN2", "gene_name": "CLN2", "gene_names_uniprotkb": "CLN2", "gene_names_refseq": "CLN2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20438", "url": "https://www.uniprot.org/uniprotkb/P20438" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000006177", "url": "https://www.yeastgenome.org/locus/S000006177", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PASSSQSHTPMRNMSSLSDN", "down_seq": "VFSRNMEQSSPITPSMYQFG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000006177", "url": "https://www.yeastgenome.org/locus/S000006177" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser417" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "430", "end_pos": "430" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "233", "end_pos": "233" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "311", "end_pos": "311" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "417", "end_pos": "417" }, { "start_pos": "427", "end_pos": "427" }, { "start_pos": "430", "end_pos": "430" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "468", "end_pos": "468" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "518", "end_pos": "518" }, { "start_pos": "525", "end_pos": "525" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "P20438-1.411.411", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P20438-1.412.412", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P20438-1.414.414", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P20438-1.427.427", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P20438-1.430.430", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20438-1.427.427", "start_pos": 427, "end_pos": 427, "uniprot_canonical_ac": "P20438-1", "length": 545, "uniprot_id": "CG12_YEAST", "protein_name": "G1/S-specific cyclin CLN2", "refseq_ac": "NP_015067", "refseq_name": "cyclin CLN2", "gene_name": "CLN2", "gene_names_uniprotkb": "CLN2", "gene_names_refseq": "CLN2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20438", "url": "https://www.uniprot.org/uniprotkb/P20438" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Rapid degradation of the G1 cyclin Cln2 induced by CDK-dependent phosphorylation.", "journal": "Science (New York, N.Y.)", "date": "1996-03-15", "authors": "Lanker S, Valdivieso M H, Wittenberg C", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" } ], "reference": [ { "type": "PubMed", "id": "8599119", "url": "https://glygen.org/publication/PubMed/8599119" } ] }, { "title": "Cdc53 targets phosphorylated G1 cyclins for degradation by the ubiquitin proteolytic pathway.", "journal": "Cell", "date": "1996-08-09", "authors": "Willems A R, Lanker S, Patton E E, Craig K L, Nason T F, Mathias N, Kobayashi R, Wittenberg C, Tyers M", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" } ], "reference": [ { "type": "PubMed", "id": "8756727", "url": "https://glygen.org/publication/PubMed/8756727" } ] } ], "crossref": [ { "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "8599119", "url": "https://glygen.org/publication/PubMed/8599119", "database": "PubMed", "categories": [ "Other" ] }, { "id": "8756727", "url": "https://glygen.org/publication/PubMed/8756727", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MRNMSSLSDNSVFSRNMEQS", "down_seq": "PITPSMYQFGQQQSNSICGS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" }, { "database": "PubMed", "id": "8599119", "url": "https://glygen.org/publication/PubMed/8599119" }, { "database": "PubMed", "id": "8756727", "url": "https://glygen.org/publication/PubMed/8756727" } ], "site_lbl": "Ser427" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "430", "end_pos": "430" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "233", "end_pos": "233" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "311", "end_pos": "311" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "417", "end_pos": "417" }, { "start_pos": "427", "end_pos": "427" }, { "start_pos": "430", "end_pos": "430" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "468", "end_pos": "468" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "518", "end_pos": "518" }, { "start_pos": "525", "end_pos": "525" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P20438-1.411.411", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P20438-1.412.412", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P20438-1.414.414", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P20438-1.417.417", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P20438-1.430.430", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20438-1.464.464", "start_pos": 464, "end_pos": 464, "uniprot_canonical_ac": "P20438-1", "length": 545, "uniprot_id": "CG12_YEAST", "protein_name": "G1/S-specific cyclin CLN2", "refseq_ac": "NP_015067", "refseq_name": "cyclin CLN2", "gene_name": "CLN2", "gene_names_uniprotkb": "CLN2", "gene_names_refseq": "CLN2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20438", "url": "https://www.uniprot.org/uniprotkb/P20438" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast.", "journal": "Science signaling", "date": "2010-12-21", "authors": "Bodenmiller Bernd, Wanka Stefanie, Kraft Claudine, Urban J\u00f6rg, Campbell David, Pedrioli Patrick G, Gerrits Bertran, Picotti Paola, Lam Henry, Vitek Olga, Brusniak Mi-Youn, Roschitzki Bernd, Zhang Chao, Shokat Kevan M, Schlapbach Ralph, Colman-Lerner Alejandro, Nolan Garry P, Nesvizhskii Alexey I, Peter Matthias, Loewith Robbie, von Mering Christian, Aebersold Ruedi", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" } ], "reference": [ { "type": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ], "crossref": [ { "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "ICGSTVSVNSLVNTNNKQRI", "down_seq": "EQITGPNSNNATNDYIDLLN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ], "site_lbl": "Tyr464" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "430", "end_pos": "430" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "233", "end_pos": "233" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "311", "end_pos": "311" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "417", "end_pos": "417" }, { "start_pos": "427", "end_pos": "427" }, { "start_pos": "430", "end_pos": "430" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "468", "end_pos": "468" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "518", "end_pos": "518" }, { "start_pos": "525", "end_pos": "525" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "P20438-1.468.468", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P20438-1.472.472", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20438-1.468.468", "start_pos": 468, "end_pos": 468, "uniprot_canonical_ac": "P20438-1", "length": 545, "uniprot_id": "CG12_YEAST", "protein_name": "G1/S-specific cyclin CLN2", "refseq_ac": "NP_015067", "refseq_name": "cyclin CLN2", "gene_name": "CLN2", "gene_names_uniprotkb": "CLN2", "gene_names_refseq": "CLN2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20438", "url": "https://www.uniprot.org/uniprotkb/P20438" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast.", "journal": "Science signaling", "date": "2010-12-21", "authors": "Bodenmiller Bernd, Wanka Stefanie, Kraft Claudine, Urban J\u00f6rg, Campbell David, Pedrioli Patrick G, Gerrits Bertran, Picotti Paola, Lam Henry, Vitek Olga, Brusniak Mi-Youn, Roschitzki Bernd, Zhang Chao, Shokat Kevan M, Schlapbach Ralph, Colman-Lerner Alejandro, Nolan Garry P, Nesvizhskii Alexey I, Peter Matthias, Loewith Robbie, von Mering Christian, Aebersold Ruedi", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" } ], "reference": [ { "type": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ], "crossref": [ { "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "TVSVNSLVNTNNKQRIYEQI", "down_seq": "GPNSNNATNDYIDLLNLNES", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ], "site_lbl": "Thr468" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "430", "end_pos": "430" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "233", "end_pos": "233" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "311", "end_pos": "311" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "417", "end_pos": "417" }, { "start_pos": "427", "end_pos": "427" }, { "start_pos": "430", "end_pos": "430" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "468", "end_pos": "468" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "518", "end_pos": "518" }, { "start_pos": "525", "end_pos": "525" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P20438-1.464.464", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P20438-1.472.472", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20438-1.472.472", "start_pos": 472, "end_pos": 472, "uniprot_canonical_ac": "P20438-1", "length": 545, "uniprot_id": "CG12_YEAST", "protein_name": "G1/S-specific cyclin CLN2", "refseq_ac": "NP_015067", "refseq_name": "cyclin CLN2", "gene_name": "CLN2", "gene_names_uniprotkb": "CLN2", "gene_names_refseq": "CLN2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20438", "url": "https://www.uniprot.org/uniprotkb/P20438" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast.", "journal": "Science signaling", "date": "2010-12-21", "authors": "Bodenmiller Bernd, Wanka Stefanie, Kraft Claudine, Urban J\u00f6rg, Campbell David, Pedrioli Patrick G, Gerrits Bertran, Picotti Paola, Lam Henry, Vitek Olga, Brusniak Mi-Youn, Roschitzki Bernd, Zhang Chao, Shokat Kevan M, Schlapbach Ralph, Colman-Lerner Alejandro, Nolan Garry P, Nesvizhskii Alexey I, Peter Matthias, Loewith Robbie, von Mering Christian, Aebersold Ruedi", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" } ], "reference": [ { "type": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ], "crossref": [ { "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000006177", "url": "https://www.yeastgenome.org/locus/S000006177", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NSLVNTNNKQRIYEQITGPN", "down_seq": "NNATNDYIDLLNLNESNKEN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000006177", "url": "https://www.yeastgenome.org/locus/S000006177" } ], "site_lbl": "Ser472" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "430", "end_pos": "430" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "233", "end_pos": "233" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "311", "end_pos": "311" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "417", "end_pos": "417" }, { "start_pos": "427", "end_pos": "427" }, { "start_pos": "430", "end_pos": "430" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "468", "end_pos": "468" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "518", "end_pos": "518" }, { "start_pos": "525", "end_pos": "525" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "P20438-1.464.464", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P20438-1.468.468", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20438-1.518.518", "start_pos": 518, "end_pos": 518, "uniprot_canonical_ac": "P20438-1", "length": 545, "uniprot_id": "CG12_YEAST", "protein_name": "G1/S-specific cyclin CLN2", "refseq_ac": "NP_015067", "refseq_name": "cyclin CLN2", "gene_name": "CLN2", "gene_names_uniprotkb": "CLN2", "gene_names_refseq": "CLN2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20438", "url": "https://www.uniprot.org/uniprotkb/P20438" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "Cdc53 targets phosphorylated G1 cyclins for degradation by the ubiquitin proteolytic pathway.", "journal": "Cell", "date": "1996-08-09", "authors": "Willems A R, Lanker S, Patton E E, Craig K L, Nason T F, Mathias N, Kobayashi R, Wittenberg C, Tyers M", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" } ], "reference": [ { "type": "PubMed", "id": "8756727", "url": "https://glygen.org/publication/PubMed/8756727" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "8756727", "url": "https://glygen.org/publication/PubMed/8756727", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000006177", "url": "https://www.yeastgenome.org/locus/S000006177", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AHYLNGGPPKTSFINHGMFP", "down_seq": "PTGTINSGKSSSASSLISFG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "8756727", "url": "https://glygen.org/publication/PubMed/8756727" }, { "database": "SGD", "id": "S000006177", "url": "https://www.yeastgenome.org/locus/S000006177" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser518" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "430", "end_pos": "430" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "233", "end_pos": "233" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "311", "end_pos": "311" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "417", "end_pos": "417" }, { "start_pos": "427", "end_pos": "427" }, { "start_pos": "430", "end_pos": "430" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "468", "end_pos": "468" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "518", "end_pos": "518" }, { "start_pos": "525", "end_pos": "525" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "upstream", "id": "P20438-1.525.525", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20438-1.525.525", "start_pos": 525, "end_pos": 525, "uniprot_canonical_ac": "P20438-1", "length": 545, "uniprot_id": "CG12_YEAST", "protein_name": "G1/S-specific cyclin CLN2", "refseq_ac": "NP_015067", "refseq_name": "cyclin CLN2", "gene_name": "CLN2", "gene_names_uniprotkb": "CLN2", "gene_names_refseq": "CLN2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20438", "url": "https://www.uniprot.org/uniprotkb/P20438" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "crossref": [ { "id": "S000006177", "url": "https://www.yeastgenome.org/locus/S000006177", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PPKTSFINHGMFPSPTGTIN", "down_seq": "GKSSSASSLISFGMGNTQVI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006177", "url": "https://www.yeastgenome.org/locus/S000006177" }, { "database": "iPTMnet", "id": "P20438", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20438" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Ser525" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "430", "end_pos": "430" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "233", "end_pos": "233" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "311", "end_pos": "311" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "414", "end_pos": "414" }, { "start_pos": "417", "end_pos": "417" }, { "start_pos": "427", "end_pos": "427" }, { "start_pos": "430", "end_pos": "430" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "468", "end_pos": "468" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "518", "end_pos": "518" }, { "start_pos": "525", "end_pos": "525" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P20438-1.518.518", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20795-1.360.360", "start_pos": 360, "end_pos": 360, "uniprot_canonical_ac": "P20795-1", "length": 691, "uniprot_id": "VPS33_YEAST", "protein_name": "Vacuolar protein sorting-associated protein 33", "refseq_ac": "NP_013500", "refseq_name": "tethering complex ATP-binding subunit VPS33", "gene_name": "VPS33", "gene_names_uniprotkb": "VPS33; L8084.15; SLP1; VAM5", "gene_names_refseq": "CLS14; MET27; PEP14; SLP1; VAM5; VPL25; VPS33; VPT33", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20795", "url": "https://www.uniprot.org/uniprotkb/P20795" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P20795", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20795" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P20795", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20795" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004388", "url": "https://www.yeastgenome.org/locus/S000004388", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P20795", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20795", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QLNKLAKELQTQYDTRHKAE", "down_seq": "VHEIKEFVDSLGSLQQRQAF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004388", "url": "https://www.yeastgenome.org/locus/S000004388" }, { "database": "iPTMnet", "id": "P20795", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20795" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser360" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "360", "end_pos": "360" }, { "start_pos": "373", "end_pos": "373" }, { "start_pos": "571", "end_pos": "571" }, { "start_pos": "618", "end_pos": "618" }, { "start_pos": "626", "end_pos": "626" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "upstream", "id": "P20795-1.373.373", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20795-1.373.373", "start_pos": 373, "end_pos": 373, "uniprot_canonical_ac": "P20795-1", "length": 691, "uniprot_id": "VPS33_YEAST", "protein_name": "Vacuolar protein sorting-associated protein 33", "refseq_ac": "NP_013500", "refseq_name": "tethering complex ATP-binding subunit VPS33", "gene_name": "VPS33", "gene_names_uniprotkb": "VPS33; L8084.15; SLP1; VAM5", "gene_names_refseq": "CLS14; MET27; PEP14; SLP1; VAM5; VPL25; VPS33; VPT33", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20795", "url": "https://www.uniprot.org/uniprotkb/P20795" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P20795", "url": "https://www.uniprot.org/uniprotkb/P20795" }, { "database": "iPTMnet", "id": "P20795", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20795" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P20795", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20795" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P20795", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20795", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004388", "url": "https://www.yeastgenome.org/locus/S000004388", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DTRHKAESVHEIKEFVDSLG", "down_seq": "LQQRQAFLKNHTTLSSDVLK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P20795", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20795" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004388", "url": "https://www.yeastgenome.org/locus/S000004388" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser373" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "360", "end_pos": "360" }, { "start_pos": "373", "end_pos": "373" }, { "start_pos": "571", "end_pos": "571" }, { "start_pos": "618", "end_pos": "618" }, { "start_pos": "626", "end_pos": "626" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P20795-1.360.360", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20795-1.571.571", "start_pos": 571, "end_pos": 571, "uniprot_canonical_ac": "P20795-1", "length": 691, "uniprot_id": "VPS33_YEAST", "protein_name": "Vacuolar protein sorting-associated protein 33", "refseq_ac": "NP_013500", "refseq_name": "tethering complex ATP-binding subunit VPS33", "gene_name": "VPS33", "gene_names_uniprotkb": "VPS33; L8084.15; SLP1; VAM5", "gene_names_refseq": "CLS14; MET27; PEP14; SLP1; VAM5; VPL25; VPS33; VPT33", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20795", "url": "https://www.uniprot.org/uniprotkb/P20795" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P20795", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20795" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004388", "url": "https://www.yeastgenome.org/locus/S000004388", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P20795", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20795", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PLTMRLVQMLYDRSILFHNY", "down_seq": "SQQPFILSREPRVSQTEDLI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004388", "url": "https://www.yeastgenome.org/locus/S000004388" }, { "database": "iPTMnet", "id": "P20795", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20795" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser571" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "360", "end_pos": "360" }, { "start_pos": "373", "end_pos": "373" }, { "start_pos": "571", "end_pos": "571" }, { "start_pos": "618", "end_pos": "618" }, { "start_pos": "626", "end_pos": "626" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20795-1.618.618", "start_pos": 618, "end_pos": 618, "uniprot_canonical_ac": "P20795-1", "length": 691, "uniprot_id": "VPS33_YEAST", "protein_name": "Vacuolar protein sorting-associated protein 33", "refseq_ac": "NP_013500", "refseq_name": "tethering complex ATP-binding subunit VPS33", "gene_name": "VPS33", "gene_names_uniprotkb": "VPS33; L8084.15; SLP1; VAM5", "gene_names_refseq": "CLS14; MET27; PEP14; SLP1; VAM5; VPL25; VPS33; VPT33", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20795", "url": "https://www.uniprot.org/uniprotkb/P20795" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P20795", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20795" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ], "crossref": [ { "id": "P20795", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20795", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SHAIEESIWVPGTITKKINA", "down_seq": "IKSNNRRSIDGSNGTFHAAE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P20795", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20795" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ], "site_lbl": "Ser618" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "360", "end_pos": "360" }, { "start_pos": "373", "end_pos": "373" }, { "start_pos": "571", "end_pos": "571" }, { "start_pos": "618", "end_pos": "618" }, { "start_pos": "626", "end_pos": "626" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "upstream", "id": "P20795-1.626.626", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P20795-1.626.626", "start_pos": 626, "end_pos": 626, "uniprot_canonical_ac": "P20795-1", "length": 691, "uniprot_id": "VPS33_YEAST", "protein_name": "Vacuolar protein sorting-associated protein 33", "refseq_ac": "NP_013500", "refseq_name": "tethering complex ATP-binding subunit VPS33", "gene_name": "VPS33", "gene_names_uniprotkb": "VPS33; L8084.15; SLP1; VAM5", "gene_names_refseq": "CLS14; MET27; PEP14; SLP1; VAM5; VPL25; VPS33; VPT33", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P20795", "url": "https://www.uniprot.org/uniprotkb/P20795" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P20795", "url": "https://www.uniprot.org/uniprotkb/P20795" }, { "database": "iPTMnet", "id": "P20795", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20795" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ], "crossref": [ { "id": "P20795", "url": "https://www.uniprot.org/uniprotkb/P20795", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P20795", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20795", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000004388", "url": "https://www.yeastgenome.org/locus/S000004388", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "WVPGTITKKINASIKSNNRR", "down_seq": "IDGSNGTFHAAEDIALVVFL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P20795", "url": "https://www.uniprot.org/uniprotkb/P20795" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P20795", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P20795" }, { "database": "SGD", "id": "S000004388", "url": "https://www.yeastgenome.org/locus/S000004388" } ], "site_lbl": "Ser626" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "360", "end_pos": "360" }, { "start_pos": "373", "end_pos": "373" }, { "start_pos": "571", "end_pos": "571" }, { "start_pos": "618", "end_pos": "618" }, { "start_pos": "626", "end_pos": "626" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "P20795-1.618.618", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.306.306", "start_pos": 306, "end_pos": 306, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Pheromone-dependent G1 cell cycle arrest requires Far1 phosphorylation, but may not involve inhibition of Cdc28-Cln2 kinase, in vivo.", "journal": "Molecular and cellular biology", "date": "1998", "authors": "Gartner A, Jovanovic A, Jeoung DI, Bourlat S, Cross FR, Ammerer G", "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "9632750", "url": "https://glygen.org/publication/PubMed/9632750" } ] }, { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "Journal of proteome research", "date": "2007-03", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "9632750", "url": "https://glygen.org/publication/PubMed/9632750", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "QQQWIDLKTARSFTGEFPQF", "down_seq": "PQEQLIRTADISCDGFRTPR", "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Abolishes G1 arrest function.", "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" }, { "database": "PubMed", "id": "9632750", "url": "https://glygen.org/publication/PubMed/9632750" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "9632750", "url": "https://glygen.org/publication/PubMed/9632750" }, { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr306" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "mutagenesis_flag", "phosphorylation_flag" ], "glycosylation": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "P21268-1.297.297", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P21268-1.299.299", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P21268-1.314.314", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P21268-1.318.318", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P21268-1.324.324", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.87.87", "start_pos": 87, "end_pos": 87, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Pheromone-dependent G1 cell cycle arrest requires Far1 phosphorylation, but may not involve inhibition of Cdc28-Cln2 kinase, in vivo.", "journal": "Molecular and cellular biology", "date": "1998", "authors": "Gartner A, Jovanovic A, Jeoung DI, Bourlat S, Cross FR, Ammerer G", "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "9632750", "url": "https://glygen.org/publication/PubMed/9632750" } ] }, { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "Journal of proteome research", "date": "2007-03", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "Phosphorylation- and ubiquitin-dependent degradation of the cyclin-dependent kinase inhibitor Far1p in budding yeast.", "journal": "Genes Dev.", "date": "1997", "authors": "Henchoz S, Chi Y, Catarin B, Herskowitz I, Deshaies R J, Peter M", "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "9367986", "url": "https://glygen.org/publication/PubMed/9367986" } ] }, { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "9632750", "url": "https://glygen.org/publication/PubMed/9632750", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "9367986", "url": "https://glygen.org/publication/PubMed/9367986", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GLMMSKRGNIPKPLNLSKPI", "down_seq": "PPPSLKKTAGSVASGFSKTG", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Prevents cell cycle-dependent degradation of FAR1.", "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" }, { "database": "PubMed", "id": "9632750", "url": "https://glygen.org/publication/PubMed/9632750" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "9367986", "url": "https://glygen.org/publication/PubMed/9367986" }, { "database": "PubMed", "id": "9632750", "url": "https://glygen.org/publication/PubMed/9632750" } ], "site_lbl": "Ser87" }, { "kinase_uniprot_canonical_ac": "P20438-1", "kinase_gene_name": "CLN2", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "9367986", "url": "https://glygen.org/publication/PubMed/9367986" }, { "database": "PubMed", "id": "9632750", "url": "https://glygen.org/publication/PubMed/9632750" } ], "site_lbl": "Ser87" }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by CDC28", "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" }, { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser87" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "mutagenesis_flag", "phosphorylation_flag" ], "glycosylation": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "P21268-1.91.91", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P21268-1.98.98", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P21268-1.101.101", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P21268-1.106.106", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.101.101", "start_pos": 101, "end_pos": 101, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] } ], "crossref": [ { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NLSKPISPPPSLKKTAGSVA", "down_seq": "GFSKTGQLSALQSPVNITSS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ], "site_lbl": "Ser101" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "P21268-1.87.87", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P21268-1.91.91", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P21268-1.98.98", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P21268-1.106.106", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P21268-1.110.110", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P21268-1.114.114", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.106.106", "start_pos": 106, "end_pos": 106, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.", "journal": "Genes & development", "date": "2009-08-15", "authors": "Huber Alexandre, Bodenmiller Bernd, Uotila Aino, Stahl Michael, Wanka Stefanie, Gerrits Bertran, Aebersold Ruedi, Loewith Robbie", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] } ], "crossref": [ { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "ISPPPSLKKTAGSVASGFSK", "down_seq": "GQLSALQSPVNITSSNKYNI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ], "site_lbl": "Thr106" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P21268-1.87.87", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P21268-1.91.91", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P21268-1.98.98", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P21268-1.101.101", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P21268-1.110.110", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P21268-1.114.114", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.110.110", "start_pos": 110, "end_pos": 110, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "Journal of proteome research", "date": "2007-03", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PSLKKTAGSVASGFSKTGQL", "down_seq": "ALQSPVNITSSNKYNIKATN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser110" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P21268-1.91.91", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P21268-1.98.98", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P21268-1.101.101", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P21268-1.106.106", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P21268-1.114.114", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.114.114", "start_pos": 114, "end_pos": 114, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "Journal of proteome research", "date": "2007-03", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.", "journal": "Molecular & cellular proteomics : MCP", "date": "2005-03", "authors": "Gruhler Albrecht, Olsen Jesper V, Mohammed Shabaz, Mortensen Peter, Faergeman Nils J, Mann Matthias, Jensen Ole N", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" } ] }, { "title": "Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.", "journal": "Genes & development", "date": "2009-08-15", "authors": "Huber Alexandre, Bodenmiller Bernd, Uotila Aino, Stahl Michael, Wanka Stefanie, Gerrits Bertran, Aebersold Ruedi, Loewith Robbie", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] }, { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KTAGSVASGFSKTGQLSALQ", "down_seq": "PVNITSSNKYNIKATNLTTS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser114" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P21268-1.98.98", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P21268-1.101.101", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P21268-1.106.106", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P21268-1.110.110", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P21268-1.132.132", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P21268-1.134.134", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.132.132", "start_pos": 132, "end_pos": 132, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] } ], "crossref": [ { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "LQSPVNITSSNKYNIKATNL", "down_seq": "TSLLRESISDSTTMCDTLSD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ], "site_lbl": "Thr132" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P21268-1.114.114", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P21268-1.134.134", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P21268-1.141.141", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P21268-1.149.149", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P21268-1.151.151", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.134.134", "start_pos": 134, "end_pos": 134, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SPVNITSSNKYNIKATNLTT", "down_seq": "LLRESISDSTTMCDTLSDIN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser134" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P21268-1.114.114", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P21268-1.132.132", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P21268-1.141.141", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P21268-1.149.149", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P21268-1.151.151", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.141.141", "start_pos": 141, "end_pos": 141, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] } ], "crossref": [ { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SNKYNIKATNLTTSLLRESI", "down_seq": "DSTTMCDTLSDINLTVMDED", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ], "site_lbl": "Ser141" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "P21268-1.132.132", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P21268-1.134.134", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P21268-1.149.149", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P21268-1.151.151", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.149.149", "start_pos": 149, "end_pos": 149, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] } ], "crossref": [ { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "TNLTTSLLRESISDSTTMCD", "down_seq": "LSDINLTVMDEDYRIDGDSY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ], "site_lbl": "Thr149" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P21268-1.132.132", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P21268-1.134.134", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P21268-1.141.141", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P21268-1.151.151", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P21268-1.168.168", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.151.151", "start_pos": 151, "end_pos": 151, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] } ], "crossref": [ { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LTTSLLRESISDSTTMCDTL", "down_seq": "DINLTVMDEDYRIDGDSYYE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ], "site_lbl": "Ser151" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P21268-1.132.132", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P21268-1.134.134", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P21268-1.141.141", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P21268-1.149.149", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P21268-1.168.168", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.15.15", "start_pos": 15, "end_pos": 15, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "MKTPTRVSFEKKIH", "down_seq": "PPSGDRDAERSPPKKFLRGL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ], "site_lbl": "Thr15" }, { "kinase_uniprot_canonical_ac": "P24869-1", "kinase_gene_name": "CLB2", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ], "site_lbl": "Thr15" }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr15" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P21268-1.3.3", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P21268-1.5.5", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P21268-1.8.8", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P21268-1.18.18", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P21268-1.26.26", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.168.168", "start_pos": 168, "end_pos": 168, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] } ], "crossref": [ { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DTLSDINLTVMDEDYRIDGD", "down_seq": "YYEEDSPTFMISLERNIKKC", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ], "site_lbl": "Ser168" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P21268-1.149.149", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P21268-1.151.151", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P21268-1.174.174", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P21268-1.176.176", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P21268-1.180.180", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.174.174", "start_pos": 174, "end_pos": 174, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NLTVMDEDYRIDGDSYYEED", "down_seq": "PTFMISLERNIKKCNSQFSP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser174" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "P21268-1.168.168", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P21268-1.176.176", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P21268-1.180.180", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P21268-1.193.193", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.176.176", "start_pos": 176, "end_pos": 176, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] } ], "crossref": [ { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "TVMDEDYRIDGDSYYEEDSP", "down_seq": "FMISLERNIKKCNSQFSPKR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ], "site_lbl": "Thr176" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "P21268-1.168.168", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P21268-1.174.174", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P21268-1.180.180", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P21268-1.193.193", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.180.180", "start_pos": 180, "end_pos": 180, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] } ], "crossref": [ { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EDYRIDGDSYYEEDSPTFMI", "down_seq": "LERNIKKCNSQFSPKRYIGE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ], "site_lbl": "Ser180" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P21268-1.168.168", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P21268-1.174.174", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P21268-1.176.176", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P21268-1.193.193", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.18.18", "start_pos": 18, "end_pos": 18, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MKTPTRVSFEKKIHTPP", "down_seq": "GDRDAERSPPKKFLRGLSGK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser18" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P21268-1.3.3", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P21268-1.5.5", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P21268-1.8.8", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P21268-1.15.15", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P21268-1.26.26", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.193.193", "start_pos": 193, "end_pos": 193, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DSPTFMISLERNIKKCNSQF", "down_seq": "PKRYIGEKCLICEESISSTF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser193" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P21268-1.174.174", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P21268-1.176.176", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P21268-1.180.180", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P21268-1.208.208", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P21268-1.210.210", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.208.208", "start_pos": 208, "end_pos": 208, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "CNSQFSPKRYIGEKCLICEE", "down_seq": "ISSTFTGEKVVESTCSHTSH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser208" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P21268-1.193.193", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P21268-1.210.210", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.210.210", "start_pos": 210, "end_pos": 210, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] } ], "crossref": [ { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SQFSPKRYIGEKCLICEESI", "down_seq": "STFTGEKVVESTCSHTSHYN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ], "site_lbl": "Ser210" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P21268-1.193.193", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P21268-1.208.208", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.26.26", "start_pos": 26, "end_pos": 26, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Systematic identification of cell cycle-dependent yeast nucleocytoplasmic shuttling proteins by prediction of composite motifs.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2009-06-23", "authors": "Kosugi Shunichi, Hasebe Masako, Tomita Masaru, Yanagawa Hiroshi", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "19520826", "url": "https://glygen.org/publication/PubMed/19520826" } ] }, { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19520826", "url": "https://glygen.org/publication/PubMed/19520826", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RVSFEKKIHTPPSGDRDAER", "down_seq": "PPKKFLRGLSGKVFRKTPEF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "19520826", "url": "https://glygen.org/publication/PubMed/19520826" }, { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser26" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P21268-1.8.8", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P21268-1.15.15", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P21268-1.18.18", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P21268-1.43.43", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.282.282", "start_pos": 282, "end_pos": 282, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] } ], "crossref": [ { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IVPEMVSKLLTGAGAHDDGP", "down_seq": "SNMQQQWIDLKTARSFTGEF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ], "site_lbl": "Ser282" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "P21268-1.283.283", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P21268-1.297.297", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P21268-1.299.299", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.283.283", "start_pos": 283, "end_pos": 283, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] } ], "crossref": [ { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VPEMVSKLLTGAGAHDDGPS", "down_seq": "NMQQQWIDLKTARSFTGEFP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ], "site_lbl": "Ser283" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "P21268-1.282.282", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P21268-1.297.297", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P21268-1.299.299", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.297.297", "start_pos": 297, "end_pos": 297, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "Journal of proteome research", "date": "2007-03", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "HDDGPSSNMQQQWIDLKTAR", "down_seq": "FTGEFPQFTPQEQLIRTADI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser297" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P21268-1.282.282", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P21268-1.283.283", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P21268-1.299.299", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P21268-1.306.306", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P21268-1.314.314", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.299.299", "start_pos": 299, "end_pos": 299, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "Journal of proteome research", "date": "2007-03", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "DGPSSNMQQQWIDLKTARSF", "down_seq": "GEFPQFTPQEQLIRTADISC", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr299" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P21268-1.282.282", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P21268-1.283.283", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P21268-1.297.297", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P21268-1.306.306", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P21268-1.314.314", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P21268-1.318.318", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.314.314", "start_pos": 314, "end_pos": 314, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] } ], "crossref": [ { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "TARSFTGEFPQFTPQEQLIR", "down_seq": "ADISCDGFRTPRLSNSNQFE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ], "site_lbl": "Thr314" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P21268-1.297.297", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P21268-1.299.299", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P21268-1.306.306", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P21268-1.318.318", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P21268-1.324.324", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P21268-1.328.328", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P21268-1.330.330", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.318.318", "start_pos": 318, "end_pos": 318, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FTGEFPQFTPQEQLIRTADI", "down_seq": "CDGFRTPRLSNSNQFEAVSY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser318" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P21268-1.299.299", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P21268-1.306.306", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P21268-1.314.314", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P21268-1.324.324", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P21268-1.328.328", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P21268-1.330.330", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P21268-1.337.337", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.324.324", "start_pos": 324, "end_pos": 324, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "QFTPQEQLIRTADISCDGFR", "down_seq": "PRLSNSNQFEAVSYLDSPFL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr324" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P21268-1.306.306", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P21268-1.314.314", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P21268-1.318.318", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P21268-1.328.328", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P21268-1.330.330", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P21268-1.337.337", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P21268-1.341.341", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.328.328", "start_pos": 328, "end_pos": 328, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] } ], "crossref": [ { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QEQLIRTADISCDGFRTPRL", "down_seq": "NSNQFEAVSYLDSPFLNSPF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ], "site_lbl": "Ser328" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "P21268-1.314.314", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P21268-1.318.318", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P21268-1.324.324", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P21268-1.330.330", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P21268-1.337.337", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P21268-1.341.341", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P21268-1.346.346", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.330.330", "start_pos": 330, "end_pos": 330, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QLIRTADISCDGFRTPRLSN", "down_seq": "NQFEAVSYLDSPFLNSPFVN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser330" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P21268-1.314.314", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P21268-1.318.318", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P21268-1.324.324", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P21268-1.328.328", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P21268-1.337.337", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P21268-1.341.341", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P21268-1.346.346", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.337.337", "start_pos": 337, "end_pos": 337, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] } ], "crossref": [ { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ISCDGFRTPRLSNSNQFEAV", "down_seq": "YLDSPFLNSPFVNKMATTDP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ], "site_lbl": "Ser337" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P21268-1.318.318", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P21268-1.324.324", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P21268-1.328.328", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P21268-1.330.330", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P21268-1.341.341", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P21268-1.346.346", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P21268-1.354.354", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.341.341", "start_pos": 341, "end_pos": 341, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GFRTPRLSNSNQFEAVSYLD", "down_seq": "PFLNSPFVNKMATTDPFDLS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser341" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P21268-1.324.324", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P21268-1.328.328", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P21268-1.330.330", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P21268-1.337.337", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P21268-1.346.346", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P21268-1.354.354", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P21268-1.361.361", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.346.346", "start_pos": 346, "end_pos": 346, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RLSNSNQFEAVSYLDSPFLN", "down_seq": "PFVNKMATTDPFDLSDDEKL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser346" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P21268-1.328.328", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P21268-1.330.330", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P21268-1.337.337", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P21268-1.341.341", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P21268-1.354.354", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P21268-1.361.361", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.354.354", "start_pos": 354, "end_pos": 354, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ], "crossref": [ { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "EAVSYLDSPFLNSPFVNKMA", "down_seq": "TDPFDLSDDEKLDCDDEIDE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ], "site_lbl": "Thr354" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P21268-1.337.337", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P21268-1.341.341", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P21268-1.346.346", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P21268-1.361.361", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.361.361", "start_pos": 361, "end_pos": 361, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "Global mapping of protein phosphorylation events identifies Ste20, Sch9 and the cell-cycle regulatory kinases Cdc28/Pho85 as mediators of fatty acid starvation responses in Saccharomyces cerevisiae.", "journal": "Molecular bioSystems", "date": "2012-03", "authors": "Pultz Dennis, Bennetzen Martin V, R\u00f8dk\u00e6r Steven Vestergaard, Zimmermann Christine, Enserink Jorrit M, Andersen Jens S, F\u00e6rgeman Nils J", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" } ] }, { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] } ], "crossref": [ { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487", "database": "PubMed", "categories": [ "Other" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SPFLNSPFVNKMATTDPFDL", "down_seq": "DDEKLDCDDEIDESAAEVWF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ], "site_lbl": "Ser361" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P21268-1.341.341", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P21268-1.346.346", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P21268-1.354.354", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.3.3", "start_pos": 3, "end_pos": 3, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast.", "journal": "Proteomics", "date": "2009-10", "authors": "Gnad Florian, de Godoy Lyris M F, Cox J\u00fcrgen, Neuhauser Nadin, Ren Shubin, Olsen Jesper V, Mann Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" } ] }, { "title": "Global analysis of the yeast osmotic stress response by quantitative proteomics.", "journal": "Molecular bioSystems", "date": "2009-11", "authors": "Soufi Boumediene, Kelstrup Christian D, Stoehr Gabriele, Fr\u00f6hlich Florian, Walther Tobias C, Olsen Jesper V", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] }, { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "MK", "down_seq": "PTRVSFEKKIHTPPSGDRDA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr3" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P21268-1.5.5", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P21268-1.8.8", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P21268-1.15.15", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P21268-1.18.18", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.400.400", "start_pos": 400, "end_pos": 400, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] } ], "crossref": [ { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "WFSKTGGEHVMVSVKFQEMR", "down_seq": "SDDLGVLQDVNHVDHEELEE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ], "site_lbl": "Thr400" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.43.43", "start_pos": 43, "end_pos": 43, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "AERSPPKKFLRGLSGKVFRK", "down_seq": "PEFKKQQMPTFGYIEESQFT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr43" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P21268-1.26.26", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.540.540", "start_pos": 540, "end_pos": 540, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FNENCEKWLLPKWKYCLENS", "down_seq": "LETLPLSEIVSTVKELSHVN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser540" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "upstream", "id": "P21268-1.557.557", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.557.557", "start_pos": 557, "end_pos": 557, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ENSSLETLPLSEIVSTVKEL", "down_seq": "HVNIIGALGAPPDVISAQSH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser557" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P21268-1.540.540", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P21268-1.573.573", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P21268-1.576.576", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.573.573", "start_pos": 573, "end_pos": 573, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] } ], "crossref": [ { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VKELSHVNIIGALGAPPDVI", "down_seq": "AQSHDSRLPWKRLHSDTPLK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ], "site_lbl": "Ser573" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P21268-1.557.557", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P21268-1.576.576", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.576.576", "start_pos": 576, "end_pos": 576, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] } ], "crossref": [ { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LSHVNIIGALGAPPDVISAQ", "down_seq": "HDSRLPWKRLHSDTPLKLIV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ], "site_lbl": "Ser576" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P21268-1.557.557", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P21268-1.573.573", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.5.5", "start_pos": 5, "end_pos": 5, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "MKTP", "down_seq": "RVSFEKKIHTPPSGDRDAER", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr5" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P21268-1.3.3", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P21268-1.8.8", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P21268-1.15.15", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P21268-1.18.18", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.700.700", "start_pos": 700, "end_pos": 700, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] } ], "crossref": [ { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "QYKVTLQTCERLASTSAYVD", "down_seq": "DDHIATGYAKQILVLNGSDV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ], "site_lbl": "Thr700" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.750.750", "start_pos": 750, "end_pos": 750, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "KKAFDQLSYHWRYEISQRRM", "down_seq": "PLNASIKQFLEELHTKRYLD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr750" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.8.8", "start_pos": 8, "end_pos": 8, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast.", "journal": "Proteomics", "date": "2009-10", "authors": "Gnad Florian, de Godoy Lyris M F, Cox J\u00fcrgen, Neuhauser Nadin, Ren Shubin, Olsen Jesper V, Mann Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" } ] }, { "title": "Global analysis of the yeast osmotic stress response by quantitative proteomics.", "journal": "Molecular bioSystems", "date": "2009-11", "authors": "Soufi Boumediene, Kelstrup Christian D, Stoehr Gabriele, Fr\u00f6hlich Florian, Walther Tobias C, Olsen Jesper V", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] }, { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MKTPTRV", "down_seq": "FEKKIHTPPSGDRDAERSPP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser8" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "P21268-1.3.3", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P21268-1.5.5", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P21268-1.15.15", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P21268-1.18.18", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P21268-1.26.26", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.91.91", "start_pos": 91, "end_pos": 91, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SKRGNIPKPLNLSKPISPPP", "down_seq": "LKKTAGSVASGFSKTGQLSA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser91" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P21268-1.87.87", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P21268-1.98.98", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P21268-1.101.101", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P21268-1.106.106", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P21268-1.110.110", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21268-1.98.98", "start_pos": 98, "end_pos": 98, "uniprot_canonical_ac": "P21268-1", "length": 830, "uniprot_id": "FAR1_YEAST", "protein_name": "Cyclin-dependent kinase inhibitor FAR1", "refseq_ac": "NP_012378", "refseq_name": "cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1", "gene_name": "FAR1", "gene_names_uniprotkb": "FAR1; J0565", "gene_names_refseq": "FAR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "Journal of proteome research", "date": "2007-03", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "UniProtKB", "id": "P21268", "url": "https://www.uniprot.org/uniprotkb/P21268" }, { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.", "journal": "The Journal of cell biology", "date": "2019-09-02", "authors": "van Drogen Frank, Mishra Ranjan, Rudolf Fabian, Walczak Michal J, Lee Sung Sik, Reiter Wolfgang, Hegemann Bj\u00f6rn, Pelet Serge, Dohnal Ilse, Binolfi Andres, Yudina Zinaida, Selenko Philipp, Wider Gerhard, Ammerer Gustav, Peter Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" } ], "reference": [ { "type": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ] } ], "crossref": [ { "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KPLNLSKPISPPPSLKKTAG", "down_seq": "VASGFSKTGQLSALQSPVNI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P21268", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21268" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "SGD", "id": "S000003693", "url": "https://www.yeastgenome.org/locus/S000003693" }, { "database": "PubMed", "id": "31315942", "url": "https://glygen.org/publication/PubMed/31315942" } ], "site_lbl": "Ser98" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "306", "end_pos": "306" }, { "start_pos": "87", "end_pos": "87" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "106", "end_pos": "106" }, { "start_pos": "110", "end_pos": "110" }, { "start_pos": "114", "end_pos": "114" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "176", "end_pos": "176" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "18", "end_pos": "18" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "282", "end_pos": "282" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "299", "end_pos": "299" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "314", "end_pos": "314" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "341", "end_pos": "341" }, { "start_pos": "346", "end_pos": "346" }, { "start_pos": "354", "end_pos": "354" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "400", "end_pos": "400" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "557", "end_pos": "557" }, { "start_pos": "573", "end_pos": "573" }, { "start_pos": "576", "end_pos": "576" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P21268-1.87.87", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P21268-1.91.91", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P21268-1.101.101", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P21268-1.106.106", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P21268-1.110.110", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P21268-1.114.114", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21269-1.273.273", "start_pos": 273, "end_pos": 273, "uniprot_canonical_ac": "P21269-1", "length": 546, "uniprot_id": "CCA1_YEAST", "protein_name": "CCA tRNA nucleotidyltransferase, mitochondrial", "refseq_ac": "NP_011095", "refseq_name": "tRNA adenylyltransferase", "gene_name": "CCA1", "gene_names_uniprotkb": "CCA1; TNT1", "gene_names_refseq": "CCA1; TNT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21269", "url": "https://www.uniprot.org/uniprotkb/P21269" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [], "crossref": [ { "id": "GLY_001160", "url": "https://data.glygen.org/GLY_001160", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "NSKISRERVGVEMEKILVGP", "down_seq": "PLLALQLIQRAHLENVIFFW", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr273", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "273", "end_pos": "273" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "189", "end_pos": "189" }, { "start_pos": "64", "end_pos": "64" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "164", "end_pos": "164" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "5", "end_pos": "5" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P21269-1.189.189", "start_pos": 189, "end_pos": 189, "uniprot_canonical_ac": "P21269-1", "length": 546, "uniprot_id": "CCA1_YEAST", "protein_name": "CCA tRNA nucleotidyltransferase, mitochondrial", "refseq_ac": "NP_011095", "refseq_name": "tRNA adenylyltransferase", "gene_name": "CCA1", "gene_names_uniprotkb": "CCA1; TNT1", "gene_names_refseq": "CCA1; TNT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21269", "url": "https://www.uniprot.org/uniprotkb/P21269" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "The ability of an arginine to tryptophan substitution in Saccharomyces cerevisiae tRNA nucleotidyltransferase to alleviate a temperature-sensitive phenotype suggests a role for motif C in active site organization.", "journal": "Biochimica et biophysica acta", "date": "2013-10", "authors": "Goring Mark E, Leibovitch Matthew, Gea-Mallorqui Ester, Karls Shawn, Richard Francis, Hanic-Joyce Pamela J, Joyce Paul B M", "evidence": [ { "database": "UniProtKB", "id": "P21269", "url": "https://www.uniprot.org/uniprotkb/P21269" } ], "reference": [ { "type": "PubMed", "id": "23872483", "url": "https://glygen.org/publication/PubMed/23872483" } ] } ], "crossref": [ { "id": "P21269", "url": "https://www.uniprot.org/uniprotkb/P21269", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "23872483", "url": "https://glygen.org/publication/PubMed/23872483", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "E", "start_aa": "E", "up_seq": "ALRRDATLNALFYNIHKGEV", "down_seq": "DFTKRGLQDLKDGVLRTPLP", "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "K", "comment": "Temperature-sensitive mutation; reduced ability to incorporate AMP and CMP at 37 degrees Celsius. Defects are compensated by mutant N-64; when associated with N-64.", "evidence": [ { "database": "UniProtKB", "id": "P21269", "url": "https://www.uniprot.org/uniprotkb/P21269" }, { "database": "PubMed", "id": "23872483", "url": "https://glygen.org/publication/PubMed/23872483" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "273", "end_pos": "273" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "189", "end_pos": "189" }, { "start_pos": "64", "end_pos": "64" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "164", "end_pos": "164" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "5", "end_pos": "5" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21269-1.64.64", "start_pos": 64, "end_pos": 64, "uniprot_canonical_ac": "P21269-1", "length": 546, "uniprot_id": "CCA1_YEAST", "protein_name": "CCA tRNA nucleotidyltransferase, mitochondrial", "refseq_ac": "NP_011095", "refseq_name": "tRNA adenylyltransferase", "gene_name": "CCA1", "gene_names_uniprotkb": "CCA1; TNT1", "gene_names_refseq": "CCA1; TNT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21269", "url": "https://www.uniprot.org/uniprotkb/P21269" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "The ability of an arginine to tryptophan substitution in Saccharomyces cerevisiae tRNA nucleotidyltransferase to alleviate a temperature-sensitive phenotype suggests a role for motif C in active site organization.", "journal": "Biochimica et biophysica acta", "date": "2013-10", "authors": "Goring Mark E, Leibovitch Matthew, Gea-Mallorqui Ester, Karls Shawn, Richard Francis, Hanic-Joyce Pamela J, Joyce Paul B M", "evidence": [ { "database": "UniProtKB", "id": "P21269", "url": "https://www.uniprot.org/uniprotkb/P21269" } ], "reference": [ { "type": "PubMed", "id": "23872483", "url": "https://glygen.org/publication/PubMed/23872483" } ] } ], "crossref": [ { "id": "P21269", "url": "https://www.uniprot.org/uniprotkb/P21269", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "23872483", "url": "https://glygen.org/publication/PubMed/23872483", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "NDYTDLYNQKYHNKPEPLTL", "down_seq": "ITGGWVRDKLLGQGSHDLDI", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "N", "comment": "No effect. Compensates K-189 mutant; when associated with K-189.", "evidence": [ { "database": "UniProtKB", "id": "P21269", "url": "https://www.uniprot.org/uniprotkb/P21269" }, { "database": "PubMed", "id": "23872483", "url": "https://glygen.org/publication/PubMed/23872483" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "273", "end_pos": "273" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "189", "end_pos": "189" }, { "start_pos": "64", "end_pos": "64" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "164", "end_pos": "164" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "5", "end_pos": "5" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21269-1.164.164", "start_pos": 164, "end_pos": 164, "uniprot_canonical_ac": "P21269-1", "length": 546, "uniprot_id": "CCA1_YEAST", "protein_name": "CCA tRNA nucleotidyltransferase, mitochondrial", "refseq_ac": "NP_011095", "refseq_name": "tRNA adenylyltransferase", "gene_name": "CCA1", "gene_names_uniprotkb": "CCA1; TNT1", "gene_names_refseq": "CCA1; TNT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21269", "url": "https://www.uniprot.org/uniprotkb/P21269" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P21269", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21269" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000970", "url": "https://www.yeastgenome.org/locus/S000000970", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21269", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21269", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "VNLRSEKYTELSRIPKVCFG", "down_seq": "PEEDALRRDATLNALFYNIH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000970", "url": "https://www.yeastgenome.org/locus/S000000970" }, { "database": "iPTMnet", "id": "P21269", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21269" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr164" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "273", "end_pos": "273" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "189", "end_pos": "189" }, { "start_pos": "64", "end_pos": "64" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "164", "end_pos": "164" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "5", "end_pos": "5" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21269-1.21.21", "start_pos": 21, "end_pos": 21, "uniprot_canonical_ac": "P21269-1", "length": 546, "uniprot_id": "CCA1_YEAST", "protein_name": "CCA tRNA nucleotidyltransferase, mitochondrial", "refseq_ac": "NP_011095", "refseq_name": "tRNA adenylyltransferase", "gene_name": "CCA1", "gene_names_uniprotkb": "CCA1; TNT1", "gene_names_refseq": "CCA1; TNT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21269", "url": "https://www.uniprot.org/uniprotkb/P21269" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "iPTMnet", "id": "P21269", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21269" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ], "crossref": [ { "id": "P21269", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21269", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000970", "url": "https://www.yeastgenome.org/locus/S000000970", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MLRSTISLLMNSAAQKTMTN", "down_seq": "NFVLNAPKITLTKVEQNICN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P21269", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21269" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000970", "url": "https://www.yeastgenome.org/locus/S000000970" } ], "site_lbl": "Ser21" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "273", "end_pos": "273" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "189", "end_pos": "189" }, { "start_pos": "64", "end_pos": "64" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "164", "end_pos": "164" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "5", "end_pos": "5" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P21269-1.4.4", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P21269-1.5.5", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21269-1.328.328", "start_pos": 328, "end_pos": 328, "uniprot_canonical_ac": "P21269-1", "length": 546, "uniprot_id": "CCA1_YEAST", "protein_name": "CCA tRNA nucleotidyltransferase, mitochondrial", "refseq_ac": "NP_011095", "refseq_name": "tRNA adenylyltransferase", "gene_name": "CCA1", "gene_names_uniprotkb": "CCA1; TNT1", "gene_names_refseq": "CCA1; TNT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21269", "url": "https://www.uniprot.org/uniprotkb/P21269" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast.", "journal": "Proteomics", "date": "2009-10", "authors": "Gnad Florian, de Godoy Lyris M F, Cox J\u00fcrgen, Neuhauser Nadin, Ren Shubin, Olsen Jesper V, Mann Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21269", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21269" } ], "reference": [ { "type": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" } ] }, { "title": "Global analysis of the yeast osmotic stress response by quantitative proteomics.", "journal": "Molecular bioSystems", "date": "2009-11", "authors": "Soufi Boumediene, Kelstrup Christian D, Stoehr Gabriele, Fr\u00f6hlich Florian, Walther Tobias C, Olsen Jesper V", "evidence": [ { "database": "iPTMnet", "id": "P21269", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21269" } ], "reference": [ { "type": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ], "crossref": [ { "id": "P21269", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21269", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QDMDKINHVYNDNILNSHLK", "down_seq": "FIELYPMFLEKLPILREKIG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P21269", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21269" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ], "site_lbl": "Ser328" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "273", "end_pos": "273" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "189", "end_pos": "189" }, { "start_pos": "64", "end_pos": "64" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "164", "end_pos": "164" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "5", "end_pos": "5" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21269-1.397.397", "start_pos": 397, "end_pos": 397, "uniprot_canonical_ac": "P21269-1", "length": 546, "uniprot_id": "CCA1_YEAST", "protein_name": "CCA tRNA nucleotidyltransferase, mitochondrial", "refseq_ac": "NP_011095", "refseq_name": "tRNA adenylyltransferase", "gene_name": "CCA1", "gene_names_uniprotkb": "CCA1; TNT1", "gene_names_refseq": "CCA1; TNT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21269", "url": "https://www.uniprot.org/uniprotkb/P21269" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P21269", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21269" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000970", "url": "https://www.yeastgenome.org/locus/S000000970", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21269", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21269", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KKINNLVSVTESIVKEGLKL", "down_seq": "KNDAAVIAKTVDSICSYEEI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000970", "url": "https://www.yeastgenome.org/locus/S000000970" }, { "database": "iPTMnet", "id": "P21269", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21269" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser397" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "273", "end_pos": "273" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "189", "end_pos": "189" }, { "start_pos": "64", "end_pos": "64" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "164", "end_pos": "164" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "5", "end_pos": "5" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21269-1.4.4", "start_pos": 4, "end_pos": 4, "uniprot_canonical_ac": "P21269-1", "length": 546, "uniprot_id": "CCA1_YEAST", "protein_name": "CCA tRNA nucleotidyltransferase, mitochondrial", "refseq_ac": "NP_011095", "refseq_name": "tRNA adenylyltransferase", "gene_name": "CCA1", "gene_names_uniprotkb": "CCA1; TNT1", "gene_names_refseq": "CCA1; TNT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21269", "url": "https://www.uniprot.org/uniprotkb/P21269" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P21269", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21269" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ], "crossref": [ { "id": "P21269", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21269", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MLR", "down_seq": "TISLLMNSAAQKTMTNSNFV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P21269", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21269" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ], "site_lbl": "Ser4" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "273", "end_pos": "273" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "189", "end_pos": "189" }, { "start_pos": "64", "end_pos": "64" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "164", "end_pos": "164" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "5", "end_pos": "5" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "P21269-1.5.5", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P21269-1.21.21", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21269-1.5.5", "start_pos": 5, "end_pos": 5, "uniprot_canonical_ac": "P21269-1", "length": 546, "uniprot_id": "CCA1_YEAST", "protein_name": "CCA tRNA nucleotidyltransferase, mitochondrial", "refseq_ac": "NP_011095", "refseq_name": "tRNA adenylyltransferase", "gene_name": "CCA1", "gene_names_uniprotkb": "CCA1; TNT1", "gene_names_refseq": "CCA1; TNT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21269", "url": "https://www.uniprot.org/uniprotkb/P21269" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P21269", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21269" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ], "crossref": [ { "id": "P21269", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21269", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "MLRS", "down_seq": "ISLLMNSAAQKTMTNSNFVL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P21269", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21269" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ], "site_lbl": "Thr5" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "273", "end_pos": "273" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "189", "end_pos": "189" }, { "start_pos": "64", "end_pos": "64" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "164", "end_pos": "164" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "5", "end_pos": "5" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "P21269-1.4.4", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P21269-1.21.21", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21524-1.608.608", "start_pos": 608, "end_pos": 608, "uniprot_canonical_ac": "P21524-1", "length": 888, "uniprot_id": "RIR1_YEAST", "protein_name": "Ribonucleoside-diphosphate reductase large chain 1", "refseq_ac": "NP_010993", "refseq_name": "ribonucleotide-diphosphate reductase subunit RNR1", "gene_name": "RNR1", "gene_names_uniprotkb": "RNR1; CRT7; RIR1; SDS12", "gene_names_refseq": "CRT7; RIR1; RNR1; SDS12", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [], "crossref": [ { "id": "GLY_001160", "url": "https://data.glygen.org/GLY_001160", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "LRKDIMKHGVRNSLTMAPMP", "down_seq": "ASTSQILGYNECFEPVTSNM", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr608", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "608", "end_pos": "608" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "428", "end_pos": "428" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "227", "end_pos": "227" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "778", "end_pos": "778" }, { "start_pos": "807", "end_pos": "807" }, { "start_pos": "808", "end_pos": "808" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "812", "end_pos": "812" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "822", "end_pos": "822" }, { "start_pos": "824", "end_pos": "824" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "863", "end_pos": "863" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "887", "end_pos": "887" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P21524-1.428.428", "start_pos": 428, "end_pos": 428, "uniprot_canonical_ac": "P21524-1", "length": 888, "uniprot_id": "RIR1_YEAST", "protein_name": "Ribonucleoside-diphosphate reductase large chain 1", "refseq_ac": "NP_010993", "refseq_name": "ribonucleotide-diphosphate reductase subunit RNR1", "gene_name": "RNR1", "gene_names_uniprotkb": "RNR1; CRT7; RIR1; SDS12", "gene_names_refseq": "CRT7; RIR1; RNR1; SDS12", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Yeast DNA damage-inducible Rnr3 has a very low catalytic activity strongly stimulated after the formation of a cross-talking Rnr1/Rnr3 complex.", "journal": "The Journal of biological chemistry", "date": "2002-05-24", "authors": "Domkin Vladimir, Thelander Lars, Chabes Andrei", "evidence": [ { "database": "UniProtKB", "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524" } ], "reference": [ { "type": "PubMed", "id": "11893751", "url": "https://glygen.org/publication/PubMed/11893751" } ] } ], "crossref": [ { "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "11893751", "url": "https://glygen.org/publication/PubMed/11893751", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "DACNRKSNQKNLGVIKSSNL", "down_seq": "CEIVEYSAPDETAVCNLASV", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Completely abolishes reductase activity.", "evidence": [ { "database": "UniProtKB", "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524" }, { "database": "PubMed", "id": "11893751", "url": "https://glygen.org/publication/PubMed/11893751" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "608", "end_pos": "608" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "428", "end_pos": "428" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "227", "end_pos": "227" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "778", "end_pos": "778" }, { "start_pos": "807", "end_pos": "807" }, { "start_pos": "808", "end_pos": "808" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "812", "end_pos": "812" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "822", "end_pos": "822" }, { "start_pos": "824", "end_pos": "824" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "863", "end_pos": "863" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "887", "end_pos": "887" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21524-1.227.227", "start_pos": 227, "end_pos": 227, "uniprot_canonical_ac": "P21524-1", "length": 888, "uniprot_id": "RIR1_YEAST", "protein_name": "Ribonucleoside-diphosphate reductase large chain 1", "refseq_ac": "NP_010993", "refseq_name": "ribonucleotide-diphosphate reductase subunit RNR1", "gene_name": "RNR1", "gene_names_uniprotkb": "RNR1; CRT7; RIR1; SDS12", "gene_names_refseq": "CRT7; RIR1; RNR1; SDS12", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524" }, { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000000872", "url": "https://www.yeastgenome.org/locus/S000000872", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NAGTPKPQMSSCFLVAMKED", "down_seq": "IEGIYDTLKECALISKTAGG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" }, { "database": "SGD", "id": "S000000872", "url": "https://www.yeastgenome.org/locus/S000000872" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser227" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "608", "end_pos": "608" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "428", "end_pos": "428" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "227", "end_pos": "227" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "778", "end_pos": "778" }, { "start_pos": "807", "end_pos": "807" }, { "start_pos": "808", "end_pos": "808" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "812", "end_pos": "812" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "822", "end_pos": "822" }, { "start_pos": "824", "end_pos": "824" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "863", "end_pos": "863" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "887", "end_pos": "887" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21524-1.765.765", "start_pos": 765, "end_pos": 765, "uniprot_canonical_ac": "P21524-1", "length": 888, "uniprot_id": "RIR1_YEAST", "protein_name": "Ribonucleoside-diphosphate reductase large chain 1", "refseq_ac": "NP_010993", "refseq_name": "ribonucleotide-diphosphate reductase subunit RNR1", "gene_name": "RNR1", "gene_names_uniprotkb": "RNR1; CRT7; RIR1; SDS12", "gene_names_refseq": "CRT7; RIR1; RNR1; SDS12", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000872", "url": "https://www.yeastgenome.org/locus/S000000872", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "TQAASAAIQFTIDQKIADQA", "down_seq": "ENVADISNLKRPSYMPSSAS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000872", "url": "https://www.yeastgenome.org/locus/S000000872" }, { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr765" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "608", "end_pos": "608" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "428", "end_pos": "428" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "227", "end_pos": "227" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "778", "end_pos": "778" }, { "start_pos": "807", "end_pos": "807" }, { "start_pos": "808", "end_pos": "808" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "812", "end_pos": "812" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "822", "end_pos": "822" }, { "start_pos": "824", "end_pos": "824" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "863", "end_pos": "863" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "887", "end_pos": "887" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "upstream", "id": "P21524-1.772.772", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P21524-1.778.778", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21524-1.772.772", "start_pos": 772, "end_pos": 772, "uniprot_canonical_ac": "P21524-1", "length": 888, "uniprot_id": "RIR1_YEAST", "protein_name": "Ribonucleoside-diphosphate reductase large chain 1", "refseq_ac": "NP_010993", "refseq_name": "ribonucleotide-diphosphate reductase subunit RNR1", "gene_name": "RNR1", "gene_names_uniprotkb": "RNR1; CRT7; RIR1; SDS12", "gene_names_refseq": "CRT7; RIR1; RNR1; SDS12", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000872", "url": "https://www.yeastgenome.org/locus/S000000872", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IQFTIDQKIADQATENVADI", "down_seq": "NLKRPSYMPSSASYAASDFV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000872", "url": "https://www.yeastgenome.org/locus/S000000872" }, { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser772" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "608", "end_pos": "608" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "428", "end_pos": "428" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "227", "end_pos": "227" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "778", "end_pos": "778" }, { "start_pos": "807", "end_pos": "807" }, { "start_pos": "808", "end_pos": "808" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "812", "end_pos": "812" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "822", "end_pos": "822" }, { "start_pos": "824", "end_pos": "824" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "863", "end_pos": "863" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "887", "end_pos": "887" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P21524-1.765.765", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P21524-1.778.778", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21524-1.778.778", "start_pos": 778, "end_pos": 778, "uniprot_canonical_ac": "P21524-1", "length": 888, "uniprot_id": "RIR1_YEAST", "protein_name": "Ribonucleoside-diphosphate reductase large chain 1", "refseq_ac": "NP_010993", "refseq_name": "ribonucleotide-diphosphate reductase subunit RNR1", "gene_name": "RNR1", "gene_names_uniprotkb": "RNR1; CRT7; RIR1; SDS12", "gene_names_refseq": "CRT7; RIR1; RNR1; SDS12", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast.", "journal": "Proteomics", "date": "2009-10", "authors": "Gnad Florian, de Godoy Lyris M F, Cox J\u00fcrgen, Neuhauser Nadin, Ren Shubin, Olsen Jesper V, Mann Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" } ] }, { "title": "Global analysis of the yeast osmotic stress response by quantitative proteomics.", "journal": "Molecular bioSystems", "date": "2009-11", "authors": "Soufi Boumediene, Kelstrup Christian D, Stoehr Gabriele, Fr\u00f6hlich Florian, Walther Tobias C, Olsen Jesper V", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ], "crossref": [ { "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QKIADQATENVADISNLKRP", "down_seq": "YMPSSASYAASDFVPAAVTA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ], "site_lbl": "Ser778" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "608", "end_pos": "608" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "428", "end_pos": "428" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "227", "end_pos": "227" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "778", "end_pos": "778" }, { "start_pos": "807", "end_pos": "807" }, { "start_pos": "808", "end_pos": "808" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "812", "end_pos": "812" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "822", "end_pos": "822" }, { "start_pos": "824", "end_pos": "824" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "863", "end_pos": "863" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "887", "end_pos": "887" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P21524-1.765.765", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P21524-1.772.772", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21524-1.807.807", "start_pos": 807, "end_pos": 807, "uniprot_canonical_ac": "P21524-1", "length": 888, "uniprot_id": "RIR1_YEAST", "protein_name": "Ribonucleoside-diphosphate reductase large chain 1", "refseq_ac": "NP_010993", "refseq_name": "ribonucleotide-diphosphate reductase subunit RNR1", "gene_name": "RNR1", "gene_names_uniprotkb": "RNR1; CRT7; RIR1; SDS12", "gene_names_refseq": "CRT7; RIR1; RNR1; SDS12", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000872", "url": "https://www.yeastgenome.org/locus/S000000872", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AASDFVPAAVTANATIPSLD", "down_seq": "SSEASREASPAPTGSHSLTK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000872", "url": "https://www.yeastgenome.org/locus/S000000872" }, { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser807" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "608", "end_pos": "608" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "428", "end_pos": "428" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "227", "end_pos": "227" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "778", "end_pos": "778" }, { "start_pos": "807", "end_pos": "807" }, { "start_pos": "808", "end_pos": "808" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "812", "end_pos": "812" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "822", "end_pos": "822" }, { "start_pos": "824", "end_pos": "824" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "863", "end_pos": "863" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "887", "end_pos": "887" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "P21524-1.808.808", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P21524-1.809.809", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P21524-1.812.812", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P21524-1.816.816", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P21524-1.820.820", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P21524-1.822.822", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P21524-1.824.824", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P21524-1.826.826", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21524-1.808.808", "start_pos": 808, "end_pos": 808, "uniprot_canonical_ac": "P21524-1", "length": 888, "uniprot_id": "RIR1_YEAST", "protein_name": "Ribonucleoside-diphosphate reductase large chain 1", "refseq_ac": "NP_010993", "refseq_name": "ribonucleotide-diphosphate reductase subunit RNR1", "gene_name": "RNR1", "gene_names_uniprotkb": "RNR1; CRT7; RIR1; SDS12", "gene_names_refseq": "CRT7; RIR1; RNR1; SDS12", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000872", "url": "https://www.yeastgenome.org/locus/S000000872", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ASDFVPAAVTANATIPSLDS", "down_seq": "SEASREASPAPTGSHSLTKG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000872", "url": "https://www.yeastgenome.org/locus/S000000872" }, { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser808" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "608", "end_pos": "608" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "428", "end_pos": "428" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "227", "end_pos": "227" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "778", "end_pos": "778" }, { "start_pos": "807", "end_pos": "807" }, { "start_pos": "808", "end_pos": "808" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "812", "end_pos": "812" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "822", "end_pos": "822" }, { "start_pos": "824", "end_pos": "824" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "863", "end_pos": "863" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "887", "end_pos": "887" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "P21524-1.807.807", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P21524-1.809.809", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P21524-1.812.812", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P21524-1.816.816", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P21524-1.820.820", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P21524-1.822.822", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P21524-1.824.824", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P21524-1.826.826", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21524-1.809.809", "start_pos": 809, "end_pos": 809, "uniprot_canonical_ac": "P21524-1", "length": 888, "uniprot_id": "RIR1_YEAST", "protein_name": "Ribonucleoside-diphosphate reductase large chain 1", "refseq_ac": "NP_010993", "refseq_name": "ribonucleotide-diphosphate reductase subunit RNR1", "gene_name": "RNR1", "gene_names_uniprotkb": "RNR1; CRT7; RIR1; SDS12", "gene_names_refseq": "CRT7; RIR1; RNR1; SDS12", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524" }, { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000872", "url": "https://www.yeastgenome.org/locus/S000000872", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SDFVPAAVTANATIPSLDSS", "down_seq": "EASREASPAPTGSHSLTKGM", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000872", "url": "https://www.yeastgenome.org/locus/S000000872" }, { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser809" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "608", "end_pos": "608" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "428", "end_pos": "428" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "227", "end_pos": "227" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "778", "end_pos": "778" }, { "start_pos": "807", "end_pos": "807" }, { "start_pos": "808", "end_pos": "808" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "812", "end_pos": "812" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "822", "end_pos": "822" }, { "start_pos": "824", "end_pos": "824" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "863", "end_pos": "863" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "887", "end_pos": "887" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P21524-1.807.807", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P21524-1.808.808", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P21524-1.812.812", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P21524-1.816.816", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P21524-1.820.820", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P21524-1.822.822", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P21524-1.824.824", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P21524-1.826.826", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21524-1.812.812", "start_pos": 812, "end_pos": 812, "uniprot_canonical_ac": "P21524-1", "length": 888, "uniprot_id": "RIR1_YEAST", "protein_name": "Ribonucleoside-diphosphate reductase large chain 1", "refseq_ac": "NP_010993", "refseq_name": "ribonucleotide-diphosphate reductase subunit RNR1", "gene_name": "RNR1", "gene_names_uniprotkb": "RNR1; CRT7; RIR1; SDS12", "gene_names_refseq": "CRT7; RIR1; RNR1; SDS12", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524" }, { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000872", "url": "https://www.yeastgenome.org/locus/S000000872", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VPAAVTANATIPSLDSSSEA", "down_seq": "REASPAPTGSHSLTKGMAEL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000872", "url": "https://www.yeastgenome.org/locus/S000000872" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser812" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "608", "end_pos": "608" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "428", "end_pos": "428" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "227", "end_pos": "227" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "778", "end_pos": "778" }, { "start_pos": "807", "end_pos": "807" }, { "start_pos": "808", "end_pos": "808" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "812", "end_pos": "812" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "822", "end_pos": "822" }, { "start_pos": "824", "end_pos": "824" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "863", "end_pos": "863" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "887", "end_pos": "887" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "P21524-1.807.807", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P21524-1.808.808", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P21524-1.809.809", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P21524-1.816.816", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P21524-1.820.820", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P21524-1.822.822", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P21524-1.824.824", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P21524-1.826.826", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21524-1.816.816", "start_pos": 816, "end_pos": 816, "uniprot_canonical_ac": "P21524-1", "length": 888, "uniprot_id": "RIR1_YEAST", "protein_name": "Ribonucleoside-diphosphate reductase large chain 1", "refseq_ac": "NP_010993", "refseq_name": "ribonucleotide-diphosphate reductase subunit RNR1", "gene_name": "RNR1", "gene_names_uniprotkb": "RNR1; CRT7; RIR1; SDS12", "gene_names_refseq": "CRT7; RIR1; RNR1; SDS12", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.", "journal": "Molecular & cellular proteomics : MCP", "date": "2005-03", "authors": "Gruhler Albrecht, Olsen Jesper V, Mohammed Shabaz, Mortensen Peter, Faergeman Nils J, Mann Matthias, Jensen Ole N", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" } ] }, { "title": "Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-06-19", "authors": "Smolka Marcus B, Albuquerque Claudio P, Chen Sheng-hong, Zhou Huilin", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524" }, { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast.", "journal": "Science signaling", "date": "2010-12-21", "authors": "Bodenmiller Bernd, Wanka Stefanie, Kraft Claudine, Urban J\u00f6rg, Campbell David, Pedrioli Patrick G, Gerrits Bertran, Picotti Paola, Lam Henry, Vitek Olga, Brusniak Mi-Youn, Roschitzki Bernd, Zhang Chao, Shokat Kevan M, Schlapbach Ralph, Colman-Lerner Alejandro, Nolan Garry P, Nesvizhskii Alexey I, Peter Matthias, Loewith Robbie, von Mering Christian, Aebersold Ruedi", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524" }, { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global mapping of protein phosphorylation events identifies Ste20, Sch9 and the cell-cycle regulatory kinases Cdc28/Pho85 as mediators of fatty acid starvation responses in Saccharomyces cerevisiae.", "journal": "Molecular bioSystems", "date": "2012-03", "authors": "Pultz Dennis, Bennetzen Martin V, R\u00f8dk\u00e6r Steven Vestergaard, Zimmermann Christine, Enserink Jorrit M, Andersen Jens S, F\u00e6rgeman Nils J", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000872", "url": "https://www.yeastgenome.org/locus/S000000872", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VTANATIPSLDSSSEASREA", "down_seq": "PAPTGSHSLTKGMAELNVQE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524" }, { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000872", "url": "https://www.yeastgenome.org/locus/S000000872" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser816" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "608", "end_pos": "608" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "428", "end_pos": "428" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "227", "end_pos": "227" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "778", "end_pos": "778" }, { "start_pos": "807", "end_pos": "807" }, { "start_pos": "808", "end_pos": "808" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "812", "end_pos": "812" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "822", "end_pos": "822" }, { "start_pos": "824", "end_pos": "824" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "863", "end_pos": "863" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "887", "end_pos": "887" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "P21524-1.807.807", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P21524-1.808.808", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P21524-1.809.809", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P21524-1.812.812", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P21524-1.820.820", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P21524-1.822.822", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P21524-1.824.824", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P21524-1.826.826", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21524-1.820.820", "start_pos": 820, "end_pos": 820, "uniprot_canonical_ac": "P21524-1", "length": 888, "uniprot_id": "RIR1_YEAST", "protein_name": "Ribonucleoside-diphosphate reductase large chain 1", "refseq_ac": "NP_010993", "refseq_name": "ribonucleotide-diphosphate reductase subunit RNR1", "gene_name": "RNR1", "gene_names_uniprotkb": "RNR1; CRT7; RIR1; SDS12", "gene_names_refseq": "CRT7; RIR1; RNR1; SDS12", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000000872", "url": "https://www.yeastgenome.org/locus/S000000872", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "ATIPSLDSSSEASREASPAP", "down_seq": "GSHSLTKGMAELNVQESKVE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000872", "url": "https://www.yeastgenome.org/locus/S000000872" }, { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr820" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "608", "end_pos": "608" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "428", "end_pos": "428" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "227", "end_pos": "227" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "778", "end_pos": "778" }, { "start_pos": "807", "end_pos": "807" }, { "start_pos": "808", "end_pos": "808" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "812", "end_pos": "812" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "822", "end_pos": "822" }, { "start_pos": "824", "end_pos": "824" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "863", "end_pos": "863" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "887", "end_pos": "887" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P21524-1.807.807", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P21524-1.808.808", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P21524-1.809.809", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P21524-1.812.812", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P21524-1.816.816", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P21524-1.822.822", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P21524-1.824.824", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P21524-1.826.826", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P21524-1.837.837", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21524-1.822.822", "start_pos": 822, "end_pos": 822, "uniprot_canonical_ac": "P21524-1", "length": 888, "uniprot_id": "RIR1_YEAST", "protein_name": "Ribonucleoside-diphosphate reductase large chain 1", "refseq_ac": "NP_010993", "refseq_name": "ribonucleotide-diphosphate reductase subunit RNR1", "gene_name": "RNR1", "gene_names_uniprotkb": "RNR1; CRT7; RIR1; SDS12", "gene_names_refseq": "CRT7; RIR1; RNR1; SDS12", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524" }, { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000872", "url": "https://www.yeastgenome.org/locus/S000000872", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IPSLDSSSEASREASPAPTG", "down_seq": "HSLTKGMAELNVQESKVEVP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000872", "url": "https://www.yeastgenome.org/locus/S000000872" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser822" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "608", "end_pos": "608" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "428", "end_pos": "428" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "227", "end_pos": "227" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "778", "end_pos": "778" }, { "start_pos": "807", "end_pos": "807" }, { "start_pos": "808", "end_pos": "808" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "812", "end_pos": "812" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "822", "end_pos": "822" }, { "start_pos": "824", "end_pos": "824" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "863", "end_pos": "863" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "887", "end_pos": "887" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P21524-1.807.807", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P21524-1.808.808", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P21524-1.809.809", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P21524-1.812.812", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P21524-1.816.816", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P21524-1.820.820", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P21524-1.824.824", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P21524-1.826.826", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P21524-1.837.837", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21524-1.824.824", "start_pos": 824, "end_pos": 824, "uniprot_canonical_ac": "P21524-1", "length": 888, "uniprot_id": "RIR1_YEAST", "protein_name": "Ribonucleoside-diphosphate reductase large chain 1", "refseq_ac": "NP_010993", "refseq_name": "ribonucleotide-diphosphate reductase subunit RNR1", "gene_name": "RNR1", "gene_names_uniprotkb": "RNR1; CRT7; RIR1; SDS12", "gene_names_refseq": "CRT7; RIR1; RNR1; SDS12", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000872", "url": "https://www.yeastgenome.org/locus/S000000872", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SLDSSSEASREASPAPTGSH", "down_seq": "LTKGMAELNVQESKVEVPEV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000872", "url": "https://www.yeastgenome.org/locus/S000000872" }, { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser824" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "608", "end_pos": "608" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "428", "end_pos": "428" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "227", "end_pos": "227" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "778", "end_pos": "778" }, { "start_pos": "807", "end_pos": "807" }, { "start_pos": "808", "end_pos": "808" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "812", "end_pos": "812" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "822", "end_pos": "822" }, { "start_pos": "824", "end_pos": "824" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "863", "end_pos": "863" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "887", "end_pos": "887" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P21524-1.807.807", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P21524-1.808.808", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P21524-1.809.809", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P21524-1.812.812", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P21524-1.816.816", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P21524-1.820.820", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P21524-1.822.822", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P21524-1.826.826", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P21524-1.837.837", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21524-1.826.826", "start_pos": 826, "end_pos": 826, "uniprot_canonical_ac": "P21524-1", "length": 888, "uniprot_id": "RIR1_YEAST", "protein_name": "Ribonucleoside-diphosphate reductase large chain 1", "refseq_ac": "NP_010993", "refseq_name": "ribonucleotide-diphosphate reductase subunit RNR1", "gene_name": "RNR1", "gene_names_uniprotkb": "RNR1; CRT7; RIR1; SDS12", "gene_names_refseq": "CRT7; RIR1; RNR1; SDS12", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000000872", "url": "https://www.yeastgenome.org/locus/S000000872", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "DSSSEASREASPAPTGSHSL", "down_seq": "KGMAELNVQESKVEVPEVPA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000872", "url": "https://www.yeastgenome.org/locus/S000000872" }, { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr826" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "608", "end_pos": "608" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "428", "end_pos": "428" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "227", "end_pos": "227" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "778", "end_pos": "778" }, { "start_pos": "807", "end_pos": "807" }, { "start_pos": "808", "end_pos": "808" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "812", "end_pos": "812" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "822", "end_pos": "822" }, { "start_pos": "824", "end_pos": "824" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "863", "end_pos": "863" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "887", "end_pos": "887" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P21524-1.807.807", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "downstream", "id": "P21524-1.808.808", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P21524-1.809.809", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P21524-1.812.812", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P21524-1.816.816", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P21524-1.820.820", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P21524-1.822.822", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P21524-1.824.824", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P21524-1.837.837", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21524-1.837.837", "start_pos": 837, "end_pos": 837, "uniprot_canonical_ac": "P21524-1", "length": 888, "uniprot_id": "RIR1_YEAST", "protein_name": "Ribonucleoside-diphosphate reductase large chain 1", "refseq_ac": "NP_010993", "refseq_name": "ribonucleotide-diphosphate reductase subunit RNR1", "gene_name": "RNR1", "gene_names_uniprotkb": "RNR1; CRT7; RIR1; SDS12", "gene_names_refseq": "CRT7; RIR1; RNR1; SDS12", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524" }, { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000000872", "url": "https://www.yeastgenome.org/locus/S000000872", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PAPTGSHSLTKGMAELNVQE", "down_seq": "KVEVPEVPAPTKNEEKAAPI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" }, { "database": "SGD", "id": "S000000872", "url": "https://www.yeastgenome.org/locus/S000000872" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser837" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "608", "end_pos": "608" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "428", "end_pos": "428" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "227", "end_pos": "227" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "778", "end_pos": "778" }, { "start_pos": "807", "end_pos": "807" }, { "start_pos": "808", "end_pos": "808" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "812", "end_pos": "812" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "822", "end_pos": "822" }, { "start_pos": "824", "end_pos": "824" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "863", "end_pos": "863" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "887", "end_pos": "887" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P21524-1.820.820", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P21524-1.822.822", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P21524-1.824.824", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P21524-1.826.826", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21524-1.863.863", "start_pos": 863, "end_pos": 863, "uniprot_canonical_ac": "P21524-1", "length": 888, "uniprot_id": "RIR1_YEAST", "protein_name": "Ribonucleoside-diphosphate reductase large chain 1", "refseq_ac": "NP_010993", "refseq_name": "ribonucleotide-diphosphate reductase subunit RNR1", "gene_name": "RNR1", "gene_names_uniprotkb": "RNR1; CRT7; RIR1; SDS12", "gene_names_refseq": "CRT7; RIR1; RNR1; SDS12", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000000872", "url": "https://www.yeastgenome.org/locus/S000000872", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "EVPAPTKNEEKAAPIVDDEE", "down_seq": "EFDIYNSKVIACAIDNPEAC", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000872", "url": "https://www.yeastgenome.org/locus/S000000872" }, { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr863" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "608", "end_pos": "608" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "428", "end_pos": "428" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "227", "end_pos": "227" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "778", "end_pos": "778" }, { "start_pos": "807", "end_pos": "807" }, { "start_pos": "808", "end_pos": "808" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "812", "end_pos": "812" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "822", "end_pos": "822" }, { "start_pos": "824", "end_pos": "824" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "863", "end_pos": "863" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "887", "end_pos": "887" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "upstream", "id": "P21524-1.870.870", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21524-1.870.870", "start_pos": 870, "end_pos": 870, "uniprot_canonical_ac": "P21524-1", "length": 888, "uniprot_id": "RIR1_YEAST", "protein_name": "Ribonucleoside-diphosphate reductase large chain 1", "refseq_ac": "NP_010993", "refseq_name": "ribonucleotide-diphosphate reductase subunit RNR1", "gene_name": "RNR1", "gene_names_uniprotkb": "RNR1; CRT7; RIR1; SDS12", "gene_names_refseq": "CRT7; RIR1; RNR1; SDS12", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000000872", "url": "https://www.yeastgenome.org/locus/S000000872", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NEEKAAPIVDDEETEFDIYN", "down_seq": "KVIACAIDNPEACEMCSG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000872", "url": "https://www.yeastgenome.org/locus/S000000872" }, { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser870" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "608", "end_pos": "608" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "428", "end_pos": "428" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "227", "end_pos": "227" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "778", "end_pos": "778" }, { "start_pos": "807", "end_pos": "807" }, { "start_pos": "808", "end_pos": "808" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "812", "end_pos": "812" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "822", "end_pos": "822" }, { "start_pos": "824", "end_pos": "824" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "863", "end_pos": "863" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "887", "end_pos": "887" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P21524-1.863.863", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P21524-1.887.887", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21524-1.887.887", "start_pos": 887, "end_pos": 887, "uniprot_canonical_ac": "P21524-1", "length": 888, "uniprot_id": "RIR1_YEAST", "protein_name": "Ribonucleoside-diphosphate reductase large chain 1", "refseq_ac": "NP_010993", "refseq_name": "ribonucleotide-diphosphate reductase subunit RNR1", "gene_name": "RNR1", "gene_names_uniprotkb": "RNR1; CRT7; RIR1; SDS12", "gene_names_refseq": "CRT7; RIR1; RNR1; SDS12", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524" }, { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524" }, { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.", "journal": "Genes & development", "date": "2009-08-15", "authors": "Huber Alexandre, Bodenmiller Bernd, Uotila Aino, Stahl Michael, Wanka Stefanie, Gerrits Bertran, Aebersold Ruedi, Loewith Robbie", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] }, { "title": "High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast.", "journal": "Proteomics", "date": "2009-10", "authors": "Gnad Florian, de Godoy Lyris M F, Cox J\u00fcrgen, Neuhauser Nadin, Ren Shubin, Olsen Jesper V, Mann Matthias", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" } ] }, { "title": "Global analysis of the yeast osmotic stress response by quantitative proteomics.", "journal": "Molecular bioSystems", "date": "2009-11", "authors": "Soufi Boumediene, Kelstrup Christian D, Stoehr Gabriele, Fr\u00f6hlich Florian, Walther Tobias C, Olsen Jesper V", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000872", "url": "https://www.yeastgenome.org/locus/S000000872", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IYNSKVIACAIDNPEACEMC", "down_seq": "", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P21524", "url": "https://www.uniprot.org/uniprotkb/P21524" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P21524", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21524" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000000872", "url": "https://www.yeastgenome.org/locus/S000000872" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser887" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "608", "end_pos": "608" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "428", "end_pos": "428" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "227", "end_pos": "227" }, { "start_pos": "765", "end_pos": "765" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "778", "end_pos": "778" }, { "start_pos": "807", "end_pos": "807" }, { "start_pos": "808", "end_pos": "808" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "812", "end_pos": "812" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "822", "end_pos": "822" }, { "start_pos": "824", "end_pos": "824" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "863", "end_pos": "863" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "887", "end_pos": "887" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P21524-1.870.870", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 9 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22082-1.151.151", "start_pos": 151, "end_pos": 151, "uniprot_canonical_ac": "P22082-1", "length": 1703, "uniprot_id": "SNF2_YEAST", "protein_name": "SWI/SNF chromatin-remodeling complex subunit SNF2", "refseq_ac": "NP_014933", "refseq_name": "SWI/SNF catalytic subunit SNF2", "gene_name": "SNF2", "gene_names_uniprotkb": "SNF2; GAM1; RIC1; SWI2; TYE3", "gene_names_refseq": "GAM1; HAF1; SNF2; SWI2; TYE3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [], "crossref": [ { "id": "GLY_001160", "url": "https://data.glygen.org/GLY_001160", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "NMLPQRQSSVGSLNATNFSP", "down_seq": "PANNGENAAEKPDNSNHNNL", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr151", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "151", "end_pos": "151" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "390", "end_pos": "390" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1340", "end_pos": "1340" }, { "start_pos": "1375", "end_pos": "1375" }, { "start_pos": "1422", "end_pos": "1422" }, { "start_pos": "1429", "end_pos": "1429" }, { "start_pos": "1470", "end_pos": "1470" }, { "start_pos": "1471", "end_pos": "1471" }, { "start_pos": "1474", "end_pos": "1474" }, { "start_pos": "1478", "end_pos": "1478" }, { "start_pos": "1480", "end_pos": "1480" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "1541", "end_pos": "1541" }, { "start_pos": "1542", "end_pos": "1542" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "364", "end_pos": "364" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "611", "end_pos": "611" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "745", "end_pos": "745" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P22082-1.149.149", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P22082-1.377.377", "start_pos": 377, "end_pos": 377, "uniprot_canonical_ac": "P22082-1", "length": 1703, "uniprot_id": "SNF2_YEAST", "protein_name": "SWI/SNF chromatin-remodeling complex subunit SNF2", "refseq_ac": "NP_014933", "refseq_name": "SWI/SNF catalytic subunit SNF2", "gene_name": "SNF2", "gene_names_uniprotkb": "SNF2; GAM1; RIC1; SWI2; TYE3", "gene_names_refseq": "GAM1; HAF1; SNF2; SWI2; TYE3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P22082", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P22082" }, { "database": "O-GlcNAc Atlas", "id": "P22082", "url": "https://oglcnac.org/atlas/detail/P22082" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] }, { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22082", "url": "https://oglcnac.org/atlas/detail/P22082", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VSPAGPSSVHNAKNGTLDKN", "down_seq": "QTVSGTPITQTESKKEENET", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser377", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P22082", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P22082" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ], "site_lbl": "Ser377" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "151", "end_pos": "151" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "390", "end_pos": "390" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1340", "end_pos": "1340" }, { "start_pos": "1375", "end_pos": "1375" }, { "start_pos": "1422", "end_pos": "1422" }, { "start_pos": "1429", "end_pos": "1429" }, { "start_pos": "1470", "end_pos": "1470" }, { "start_pos": "1471", "end_pos": "1471" }, { "start_pos": "1474", "end_pos": "1474" }, { "start_pos": "1478", "end_pos": "1478" }, { "start_pos": "1480", "end_pos": "1480" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "1541", "end_pos": "1541" }, { "start_pos": "1542", "end_pos": "1542" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "364", "end_pos": "364" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "611", "end_pos": "611" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "745", "end_pos": "745" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P22082-1.358.358", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P22082-1.364.364", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P22082-1.381.381", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P22082-1.383.383", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P22082-1.390.390", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22082-1.381.381", "start_pos": 381, "end_pos": 381, "uniprot_canonical_ac": "P22082-1", "length": 1703, "uniprot_id": "SNF2_YEAST", "protein_name": "SWI/SNF chromatin-remodeling complex subunit SNF2", "refseq_ac": "NP_014933", "refseq_name": "SWI/SNF catalytic subunit SNF2", "gene_name": "SNF2", "gene_names_uniprotkb": "SNF2; GAM1; RIC1; SWI2; TYE3", "gene_names_refseq": "GAM1; HAF1; SNF2; SWI2; TYE3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P22082", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P22082" }, { "database": "O-GlcNAc Atlas", "id": "P22082", "url": "https://oglcnac.org/atlas/detail/P22082" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" }, { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22082", "url": "https://oglcnac.org/atlas/detail/P22082", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GPSSVHNAKNGTLDKNSQTV", "down_seq": "GTPITQTESKKEENETISNV", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser381", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P22082", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P22082" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816" } ], "site_lbl": "Ser381" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "151", "end_pos": "151" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "390", "end_pos": "390" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1340", "end_pos": "1340" }, { "start_pos": "1375", "end_pos": "1375" }, { "start_pos": "1422", "end_pos": "1422" }, { "start_pos": "1429", "end_pos": "1429" }, { "start_pos": "1470", "end_pos": "1470" }, { "start_pos": "1471", "end_pos": "1471" }, { "start_pos": "1474", "end_pos": "1474" }, { "start_pos": "1478", "end_pos": "1478" }, { "start_pos": "1480", "end_pos": "1480" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "1541", "end_pos": "1541" }, { "start_pos": "1542", "end_pos": "1542" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "364", "end_pos": "364" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "611", "end_pos": "611" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "745", "end_pos": "745" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P22082-1.364.364", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P22082-1.377.377", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P22082-1.383.383", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P22082-1.390.390", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22082-1.390.390", "start_pos": 390, "end_pos": 390, "uniprot_canonical_ac": "P22082-1", "length": 1703, "uniprot_id": "SNF2_YEAST", "protein_name": "SWI/SNF chromatin-remodeling complex subunit SNF2", "refseq_ac": "NP_014933", "refseq_name": "SWI/SNF catalytic subunit SNF2", "gene_name": "SNF2", "gene_names_uniprotkb": "SNF2; GAM1; RIC1; SWI2; TYE3", "gene_names_refseq": "GAM1; HAF1; SNF2; SWI2; TYE3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P22082", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P22082" }, { "database": "O-GlcNAc Atlas", "id": "P22082", "url": "https://oglcnac.org/atlas/detail/P22082" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22082", "url": "https://oglcnac.org/atlas/detail/P22082", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NGTLDKNSQTVSGTPITQTE", "down_seq": "KKEENETISNVAKTAPNSNK", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser390", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P22082", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P22082" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "151", "end_pos": "151" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "390", "end_pos": "390" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1340", "end_pos": "1340" }, { "start_pos": "1375", "end_pos": "1375" }, { "start_pos": "1422", "end_pos": "1422" }, { "start_pos": "1429", "end_pos": "1429" }, { "start_pos": "1470", "end_pos": "1470" }, { "start_pos": "1471", "end_pos": "1471" }, { "start_pos": "1474", "end_pos": "1474" }, { "start_pos": "1478", "end_pos": "1478" }, { "start_pos": "1480", "end_pos": "1480" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "1541", "end_pos": "1541" }, { "start_pos": "1542", "end_pos": "1542" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "364", "end_pos": "364" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "611", "end_pos": "611" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "745", "end_pos": "745" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P22082-1.377.377", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P22082-1.381.381", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P22082-1.383.383", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22082-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "P22082-1", "length": 1703, "uniprot_id": "SNF2_YEAST", "protein_name": "SWI/SNF chromatin-remodeling complex subunit SNF2", "refseq_ac": "NP_014933", "refseq_name": "SWI/SNF catalytic subunit SNF2", "gene_name": "SNF2", "gene_names_uniprotkb": "SNF2; GAM1; RIC1; SWI2; TYE3", "gene_names_refseq": "GAM1; HAF1; SNF2; SWI2; TYE3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P22082", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P22082" }, { "database": "O-GlcNAc Atlas", "id": "P22082", "url": "https://oglcnac.org/atlas/detail/P22082" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22082", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P22082", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P22082", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P22082" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "151", "end_pos": "151" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "390", "end_pos": "390" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1340", "end_pos": "1340" }, { "start_pos": "1375", "end_pos": "1375" }, { "start_pos": "1422", "end_pos": "1422" }, { "start_pos": "1429", "end_pos": "1429" }, { "start_pos": "1470", "end_pos": "1470" }, { "start_pos": "1471", "end_pos": "1471" }, { "start_pos": "1474", "end_pos": "1474" }, { "start_pos": "1478", "end_pos": "1478" }, { "start_pos": "1480", "end_pos": "1480" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "1541", "end_pos": "1541" }, { "start_pos": "1542", "end_pos": "1542" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "364", "end_pos": "364" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "611", "end_pos": "611" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "745", "end_pos": "745" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22082-1.1340.1340", "start_pos": 1340, "end_pos": 1340, "uniprot_canonical_ac": "P22082-1", "length": 1703, "uniprot_id": "SNF2_YEAST", "protein_name": "SWI/SNF chromatin-remodeling complex subunit SNF2", "refseq_ac": "NP_014933", "refseq_name": "SWI/SNF catalytic subunit SNF2", "gene_name": "SNF2", "gene_names_uniprotkb": "SNF2; GAM1; RIC1; SWI2; TYE3", "gene_names_refseq": "GAM1; HAF1; SNF2; SWI2; TYE3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" }, { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-06-19", "authors": "Smolka Marcus B, Albuquerque Claudio P, Chen Sheng-hong, Zhou Huilin", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KSELPDIYSRDIGAELKREE", "down_seq": "ESAAVYNGRGARERKTATYN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1340" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "151", "end_pos": "151" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "390", "end_pos": "390" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1340", "end_pos": "1340" }, { "start_pos": "1375", "end_pos": "1375" }, { "start_pos": "1422", "end_pos": "1422" }, { "start_pos": "1429", "end_pos": "1429" }, { "start_pos": "1470", "end_pos": "1470" }, { "start_pos": "1471", "end_pos": "1471" }, { "start_pos": "1474", "end_pos": "1474" }, { "start_pos": "1478", "end_pos": "1478" }, { "start_pos": "1480", "end_pos": "1480" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "1541", "end_pos": "1541" }, { "start_pos": "1542", "end_pos": "1542" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "364", "end_pos": "364" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "611", "end_pos": "611" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "745", "end_pos": "745" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22082-1.1375.1375", "start_pos": 1375, "end_pos": 1375, "uniprot_canonical_ac": "P22082-1", "length": 1703, "uniprot_id": "SNF2_YEAST", "protein_name": "SWI/SNF chromatin-remodeling complex subunit SNF2", "refseq_ac": "NP_014933", "refseq_name": "SWI/SNF catalytic subunit SNF2", "gene_name": "SNF2", "gene_names_uniprotkb": "SNF2; GAM1; RIC1; SWI2; TYE3", "gene_names_refseq": "GAM1; HAF1; SNF2; SWI2; TYE3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-06-19", "authors": "Smolka Marcus B, Albuquerque Claudio P, Chen Sheng-hong, Zhou Huilin", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" }, { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "Global mapping of protein phosphorylation events identifies Ste20, Sch9 and the cell-cycle regulatory kinases Cdc28/Pho85 as mediators of fatty acid starvation responses in Saccharomyces cerevisiae.", "journal": "Molecular bioSystems", "date": "2012-03", "authors": "Pultz Dennis, Bennetzen Martin V, R\u00f8dk\u00e6r Steven Vestergaard, Zimmermann Christine, Enserink Jorrit M, Andersen Jens S, F\u00e6rgeman Nils J", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KTATYNDNMSEEQWLRQFEV", "down_seq": "DDEKNDKQARKQRTKKEDKS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1375" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "151", "end_pos": "151" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "390", "end_pos": "390" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1340", "end_pos": "1340" }, { "start_pos": "1375", "end_pos": "1375" }, { "start_pos": "1422", "end_pos": "1422" }, { "start_pos": "1429", "end_pos": "1429" }, { "start_pos": "1470", "end_pos": "1470" }, { "start_pos": "1471", "end_pos": "1471" }, { "start_pos": "1474", "end_pos": "1474" }, { "start_pos": "1478", "end_pos": "1478" }, { "start_pos": "1480", "end_pos": "1480" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "1541", "end_pos": "1541" }, { "start_pos": "1542", "end_pos": "1542" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "364", "end_pos": "364" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "611", "end_pos": "611" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "745", "end_pos": "745" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22082-1.1422.1422", "start_pos": 1422, "end_pos": 1422, "uniprot_canonical_ac": "P22082-1", "length": 1703, "uniprot_id": "SNF2_YEAST", "protein_name": "SWI/SNF chromatin-remodeling complex subunit SNF2", "refseq_ac": "NP_014933", "refseq_name": "SWI/SNF catalytic subunit SNF2", "gene_name": "SNF2", "gene_names_uniprotkb": "SNF2; GAM1; RIC1; SWI2; TYE3", "gene_names_refseq": "GAM1; HAF1; SNF2; SWI2; TYE3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GEIKGENIDADNDGPRINNI", "down_seq": "AEDRADTDLAMNDDDFLSKK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816" }, { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1422" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "151", "end_pos": "151" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "390", "end_pos": "390" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1340", "end_pos": "1340" }, { "start_pos": "1375", "end_pos": "1375" }, { "start_pos": "1422", "end_pos": "1422" }, { "start_pos": "1429", "end_pos": "1429" }, { "start_pos": "1470", "end_pos": "1470" }, { "start_pos": "1471", "end_pos": "1471" }, { "start_pos": "1474", "end_pos": "1474" }, { "start_pos": "1478", "end_pos": "1478" }, { "start_pos": "1480", "end_pos": "1480" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "1541", "end_pos": "1541" }, { "start_pos": "1542", "end_pos": "1542" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "364", "end_pos": "364" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "611", "end_pos": "611" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "745", "end_pos": "745" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "upstream", "id": "P22082-1.1429.1429", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22082-1.1429.1429", "start_pos": 1429, "end_pos": 1429, "uniprot_canonical_ac": "P22082-1", "length": 1703, "uniprot_id": "SNF2_YEAST", "protein_name": "SWI/SNF chromatin-remodeling complex subunit SNF2", "refseq_ac": "NP_014933", "refseq_name": "SWI/SNF catalytic subunit SNF2", "gene_name": "SNF2", "gene_names_uniprotkb": "SNF2; GAM1; RIC1; SWI2; TYE3", "gene_names_refseq": "GAM1; HAF1; SNF2; SWI2; TYE3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "IDADNDGPRINNISAEDRAD", "down_seq": "DLAMNDDDFLSKKRKAGRPR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816" }, { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr1429" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "151", "end_pos": "151" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "390", "end_pos": "390" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1340", "end_pos": "1340" }, { "start_pos": "1375", "end_pos": "1375" }, { "start_pos": "1422", "end_pos": "1422" }, { "start_pos": "1429", "end_pos": "1429" }, { "start_pos": "1470", "end_pos": "1470" }, { "start_pos": "1471", "end_pos": "1471" }, { "start_pos": "1474", "end_pos": "1474" }, { "start_pos": "1478", "end_pos": "1478" }, { "start_pos": "1480", "end_pos": "1480" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "1541", "end_pos": "1541" }, { "start_pos": "1542", "end_pos": "1542" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "364", "end_pos": "364" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "611", "end_pos": "611" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "745", "end_pos": "745" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P22082-1.1422.1422", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22082-1.1470.1470", "start_pos": 1470, "end_pos": 1470, "uniprot_canonical_ac": "P22082-1", "length": 1703, "uniprot_id": "SNF2_YEAST", "protein_name": "SWI/SNF chromatin-remodeling complex subunit SNF2", "refseq_ac": "NP_014933", "refseq_name": "SWI/SNF catalytic subunit SNF2", "gene_name": "SNF2", "gene_names_uniprotkb": "SNF2; GAM1; RIC1; SWI2; TYE3", "gene_names_refseq": "GAM1; HAF1; SNF2; SWI2; TYE3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" }, { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "crossref": [ { "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GRPKKVKLEGSENSEPPALE", "down_seq": "SPVTGDNSPSEDFMDIPKPR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816" }, { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Ser1470" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "151", "end_pos": "151" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "390", "end_pos": "390" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1340", "end_pos": "1340" }, { "start_pos": "1375", "end_pos": "1375" }, { "start_pos": "1422", "end_pos": "1422" }, { "start_pos": "1429", "end_pos": "1429" }, { "start_pos": "1470", "end_pos": "1470" }, { "start_pos": "1471", "end_pos": "1471" }, { "start_pos": "1474", "end_pos": "1474" }, { "start_pos": "1478", "end_pos": "1478" }, { "start_pos": "1480", "end_pos": "1480" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "1541", "end_pos": "1541" }, { "start_pos": "1542", "end_pos": "1542" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "364", "end_pos": "364" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "611", "end_pos": "611" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "745", "end_pos": "745" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "P22082-1.1471.1471", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P22082-1.1474.1474", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P22082-1.1478.1478", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P22082-1.1480.1480", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22082-1.1471.1471", "start_pos": 1471, "end_pos": 1471, "uniprot_canonical_ac": "P22082-1", "length": 1703, "uniprot_id": "SNF2_YEAST", "protein_name": "SWI/SNF chromatin-remodeling complex subunit SNF2", "refseq_ac": "NP_014933", "refseq_name": "SWI/SNF catalytic subunit SNF2", "gene_name": "SNF2", "gene_names_uniprotkb": "SNF2; GAM1; RIC1; SWI2; TYE3", "gene_names_refseq": "GAM1; HAF1; SNF2; SWI2; TYE3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "crossref": [ { "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RPKKVKLEGSENSEPPALES", "down_seq": "PVTGDNSPSEDFMDIPKPRT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816" }, { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Ser1471" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "151", "end_pos": "151" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "390", "end_pos": "390" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1340", "end_pos": "1340" }, { "start_pos": "1375", "end_pos": "1375" }, { "start_pos": "1422", "end_pos": "1422" }, { "start_pos": "1429", "end_pos": "1429" }, { "start_pos": "1470", "end_pos": "1470" }, { "start_pos": "1471", "end_pos": "1471" }, { "start_pos": "1474", "end_pos": "1474" }, { "start_pos": "1478", "end_pos": "1478" }, { "start_pos": "1480", "end_pos": "1480" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "1541", "end_pos": "1541" }, { "start_pos": "1542", "end_pos": "1542" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "364", "end_pos": "364" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "611", "end_pos": "611" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "745", "end_pos": "745" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "P22082-1.1470.1470", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P22082-1.1474.1474", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P22082-1.1478.1478", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P22082-1.1480.1480", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22082-1.1474.1474", "start_pos": 1474, "end_pos": 1474, "uniprot_canonical_ac": "P22082-1", "length": 1703, "uniprot_id": "SNF2_YEAST", "protein_name": "SWI/SNF chromatin-remodeling complex subunit SNF2", "refseq_ac": "NP_014933", "refseq_name": "SWI/SNF catalytic subunit SNF2", "gene_name": "SNF2", "gene_names_uniprotkb": "SNF2; GAM1; RIC1; SWI2; TYE3", "gene_names_refseq": "GAM1; HAF1; SNF2; SWI2; TYE3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "KVKLEGSENSEPPALESSPV", "down_seq": "GDNSPSEDFMDIPKPRTAGK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816" }, { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr1474" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "151", "end_pos": "151" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "390", "end_pos": "390" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1340", "end_pos": "1340" }, { "start_pos": "1375", "end_pos": "1375" }, { "start_pos": "1422", "end_pos": "1422" }, { "start_pos": "1429", "end_pos": "1429" }, { "start_pos": "1470", "end_pos": "1470" }, { "start_pos": "1471", "end_pos": "1471" }, { "start_pos": "1474", "end_pos": "1474" }, { "start_pos": "1478", "end_pos": "1478" }, { "start_pos": "1480", "end_pos": "1480" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "1541", "end_pos": "1541" }, { "start_pos": "1542", "end_pos": "1542" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "364", "end_pos": "364" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "611", "end_pos": "611" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "745", "end_pos": "745" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P22082-1.1470.1470", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P22082-1.1471.1471", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P22082-1.1478.1478", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P22082-1.1480.1480", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22082-1.1478.1478", "start_pos": 1478, "end_pos": 1478, "uniprot_canonical_ac": "P22082-1", "length": 1703, "uniprot_id": "SNF2_YEAST", "protein_name": "SWI/SNF chromatin-remodeling complex subunit SNF2", "refseq_ac": "NP_014933", "refseq_name": "SWI/SNF catalytic subunit SNF2", "gene_name": "SNF2", "gene_names_uniprotkb": "SNF2; GAM1; RIC1; SWI2; TYE3", "gene_names_refseq": "GAM1; HAF1; SNF2; SWI2; TYE3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-06-19", "authors": "Smolka Marcus B, Albuquerque Claudio P, Chen Sheng-hong, Zhou Huilin", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" }, { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EGSENSEPPALESSPVTGDN", "down_seq": "PSEDFMDIPKPRTAGKTSVK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1478" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "151", "end_pos": "151" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "390", "end_pos": "390" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1340", "end_pos": "1340" }, { "start_pos": "1375", "end_pos": "1375" }, { "start_pos": "1422", "end_pos": "1422" }, { "start_pos": "1429", "end_pos": "1429" }, { "start_pos": "1470", "end_pos": "1470" }, { "start_pos": "1471", "end_pos": "1471" }, { "start_pos": "1474", "end_pos": "1474" }, { "start_pos": "1478", "end_pos": "1478" }, { "start_pos": "1480", "end_pos": "1480" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "1541", "end_pos": "1541" }, { "start_pos": "1542", "end_pos": "1542" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "364", "end_pos": "364" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "611", "end_pos": "611" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "745", "end_pos": "745" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "P22082-1.1470.1470", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P22082-1.1471.1471", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P22082-1.1474.1474", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P22082-1.1480.1480", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22082-1.1480.1480", "start_pos": 1480, "end_pos": 1480, "uniprot_canonical_ac": "P22082-1", "length": 1703, "uniprot_id": "SNF2_YEAST", "protein_name": "SWI/SNF chromatin-remodeling complex subunit SNF2", "refseq_ac": "NP_014933", "refseq_name": "SWI/SNF catalytic subunit SNF2", "gene_name": "SNF2", "gene_names_uniprotkb": "SNF2; GAM1; RIC1; SWI2; TYE3", "gene_names_refseq": "GAM1; HAF1; SNF2; SWI2; TYE3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" }, { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SENSEPPALESSPVTGDNSP", "down_seq": "EDFMDIPKPRTAGKTSVKSA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1480" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "151", "end_pos": "151" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "390", "end_pos": "390" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1340", "end_pos": "1340" }, { "start_pos": "1375", "end_pos": "1375" }, { "start_pos": "1422", "end_pos": "1422" }, { "start_pos": "1429", "end_pos": "1429" }, { "start_pos": "1470", "end_pos": "1470" }, { "start_pos": "1471", "end_pos": "1471" }, { "start_pos": "1474", "end_pos": "1474" }, { "start_pos": "1478", "end_pos": "1478" }, { "start_pos": "1480", "end_pos": "1480" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "1541", "end_pos": "1541" }, { "start_pos": "1542", "end_pos": "1542" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "364", "end_pos": "364" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "611", "end_pos": "611" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "745", "end_pos": "745" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "P22082-1.1470.1470", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P22082-1.1471.1471", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P22082-1.1474.1474", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P22082-1.1478.1478", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22082-1.149.149", "start_pos": 149, "end_pos": 149, "uniprot_canonical_ac": "P22082-1", "length": 1703, "uniprot_id": "SNF2_YEAST", "protein_name": "SWI/SNF chromatin-remodeling complex subunit SNF2", "refseq_ac": "NP_014933", "refseq_name": "SWI/SNF catalytic subunit SNF2", "gene_name": "SNF2", "gene_names_uniprotkb": "SNF2; GAM1; RIC1; SWI2; TYE3", "gene_names_refseq": "GAM1; HAF1; SNF2; SWI2; TYE3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GNNMLPQRQSSVGSLNATNF", "down_seq": "PTPANNGENAAEKPDNSNHN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816" }, { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser149" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "151", "end_pos": "151" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "390", "end_pos": "390" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1340", "end_pos": "1340" }, { "start_pos": "1375", "end_pos": "1375" }, { "start_pos": "1422", "end_pos": "1422" }, { "start_pos": "1429", "end_pos": "1429" }, { "start_pos": "1470", "end_pos": "1470" }, { "start_pos": "1471", "end_pos": "1471" }, { "start_pos": "1474", "end_pos": "1474" }, { "start_pos": "1478", "end_pos": "1478" }, { "start_pos": "1480", "end_pos": "1480" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "1541", "end_pos": "1541" }, { "start_pos": "1542", "end_pos": "1542" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "364", "end_pos": "364" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "611", "end_pos": "611" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "745", "end_pos": "745" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P22082-1.151.151", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22082-1.1541.1541", "start_pos": 1541, "end_pos": 1541, "uniprot_canonical_ac": "P22082-1", "length": 1703, "uniprot_id": "SNF2_YEAST", "protein_name": "SWI/SNF chromatin-remodeling complex subunit SNF2", "refseq_ac": "NP_014933", "refseq_name": "SWI/SNF catalytic subunit SNF2", "gene_name": "SNF2", "gene_names_uniprotkb": "SNF2; GAM1; RIC1; SWI2; TYE3", "gene_names_refseq": "GAM1; HAF1; SNF2; SWI2; TYE3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "RGRPPKARNGLDYVRTPAAA", "down_seq": "SPIDIREKVAKQALDLYHFA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816" }, { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr1541" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "151", "end_pos": "151" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "390", "end_pos": "390" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1340", "end_pos": "1340" }, { "start_pos": "1375", "end_pos": "1375" }, { "start_pos": "1422", "end_pos": "1422" }, { "start_pos": "1429", "end_pos": "1429" }, { "start_pos": "1470", "end_pos": "1470" }, { "start_pos": "1471", "end_pos": "1471" }, { "start_pos": "1474", "end_pos": "1474" }, { "start_pos": "1478", "end_pos": "1478" }, { "start_pos": "1480", "end_pos": "1480" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "1541", "end_pos": "1541" }, { "start_pos": "1542", "end_pos": "1542" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "364", "end_pos": "364" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "611", "end_pos": "611" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "745", "end_pos": "745" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "P22082-1.1542.1542", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22082-1.1542.1542", "start_pos": 1542, "end_pos": 1542, "uniprot_canonical_ac": "P22082-1", "length": 1703, "uniprot_id": "SNF2_YEAST", "protein_name": "SWI/SNF chromatin-remodeling complex subunit SNF2", "refseq_ac": "NP_014933", "refseq_name": "SWI/SNF catalytic subunit SNF2", "gene_name": "SNF2", "gene_names_uniprotkb": "SNF2; GAM1; RIC1; SWI2; TYE3", "gene_names_refseq": "GAM1; HAF1; SNF2; SWI2; TYE3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GRPPKARNGLDYVRTPAAAT", "down_seq": "PIDIREKVAKQALDLYHFAL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816" }, { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1542" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "151", "end_pos": "151" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "390", "end_pos": "390" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1340", "end_pos": "1340" }, { "start_pos": "1375", "end_pos": "1375" }, { "start_pos": "1422", "end_pos": "1422" }, { "start_pos": "1429", "end_pos": "1429" }, { "start_pos": "1470", "end_pos": "1470" }, { "start_pos": "1471", "end_pos": "1471" }, { "start_pos": "1474", "end_pos": "1474" }, { "start_pos": "1478", "end_pos": "1478" }, { "start_pos": "1480", "end_pos": "1480" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "1541", "end_pos": "1541" }, { "start_pos": "1542", "end_pos": "1542" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "364", "end_pos": "364" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "611", "end_pos": "611" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "745", "end_pos": "745" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "P22082-1.1541.1541", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22082-1.356.356", "start_pos": 356, "end_pos": 356, "uniprot_canonical_ac": "P22082-1", "length": 1703, "uniprot_id": "SNF2_YEAST", "protein_name": "SWI/SNF chromatin-remodeling complex subunit SNF2", "refseq_ac": "NP_014933", "refseq_name": "SWI/SNF catalytic subunit SNF2", "gene_name": "SNF2", "gene_names_uniprotkb": "SNF2; GAM1; RIC1; SWI2; TYE3", "gene_names_refseq": "GAM1; HAF1; SNF2; SWI2; TYE3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" }, { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] } ], "crossref": [ { "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DNVSGLTRNAPLDSKDENFA", "down_seq": "VSPAGPSSVHNAKNGTLDKN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816" } ], "site_lbl": "Ser356" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "151", "end_pos": "151" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "390", "end_pos": "390" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1340", "end_pos": "1340" }, { "start_pos": "1375", "end_pos": "1375" }, { "start_pos": "1422", "end_pos": "1422" }, { "start_pos": "1429", "end_pos": "1429" }, { "start_pos": "1470", "end_pos": "1470" }, { "start_pos": "1471", "end_pos": "1471" }, { "start_pos": "1474", "end_pos": "1474" }, { "start_pos": "1478", "end_pos": "1478" }, { "start_pos": "1480", "end_pos": "1480" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "1541", "end_pos": "1541" }, { "start_pos": "1542", "end_pos": "1542" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "364", "end_pos": "364" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "611", "end_pos": "611" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "745", "end_pos": "745" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P22082-1.358.358", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P22082-1.364.364", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22082-1.358.358", "start_pos": 358, "end_pos": 358, "uniprot_canonical_ac": "P22082-1", "length": 1703, "uniprot_id": "SNF2_YEAST", "protein_name": "SWI/SNF chromatin-remodeling complex subunit SNF2", "refseq_ac": "NP_014933", "refseq_name": "SWI/SNF catalytic subunit SNF2", "gene_name": "SNF2", "gene_names_uniprotkb": "SNF2; GAM1; RIC1; SWI2; TYE3", "gene_names_refseq": "GAM1; HAF1; SNF2; SWI2; TYE3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" }, { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "Journal of proteome research", "date": "2007-03", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" }, { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" }, { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-06-19", "authors": "Smolka Marcus B, Albuquerque Claudio P, Chen Sheng-hong, Zhou Huilin", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] }, { "title": "Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast.", "journal": "Science signaling", "date": "2010-12-21", "authors": "Bodenmiller Bernd, Wanka Stefanie, Kraft Claudine, Urban J\u00f6rg, Campbell David, Pedrioli Patrick G, Gerrits Bertran, Picotti Paola, Lam Henry, Vitek Olga, Brusniak Mi-Youn, Roschitzki Bernd, Zhang Chao, Shokat Kevan M, Schlapbach Ralph, Colman-Lerner Alejandro, Nolan Garry P, Nesvizhskii Alexey I, Peter Matthias, Loewith Robbie, von Mering Christian, Aebersold Ruedi", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VSGLTRNAPLDSKDENFASV", "down_seq": "PAGPSSVHNAKNGTLDKNSQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser358" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "151", "end_pos": "151" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "390", "end_pos": "390" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1340", "end_pos": "1340" }, { "start_pos": "1375", "end_pos": "1375" }, { "start_pos": "1422", "end_pos": "1422" }, { "start_pos": "1429", "end_pos": "1429" }, { "start_pos": "1470", "end_pos": "1470" }, { "start_pos": "1471", "end_pos": "1471" }, { "start_pos": "1474", "end_pos": "1474" }, { "start_pos": "1478", "end_pos": "1478" }, { "start_pos": "1480", "end_pos": "1480" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "1541", "end_pos": "1541" }, { "start_pos": "1542", "end_pos": "1542" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "364", "end_pos": "364" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "611", "end_pos": "611" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "745", "end_pos": "745" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P22082-1.356.356", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P22082-1.364.364", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P22082-1.377.377", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22082-1.364.364", "start_pos": 364, "end_pos": 364, "uniprot_canonical_ac": "P22082-1", "length": 1703, "uniprot_id": "SNF2_YEAST", "protein_name": "SWI/SNF chromatin-remodeling complex subunit SNF2", "refseq_ac": "NP_014933", "refseq_name": "SWI/SNF catalytic subunit SNF2", "gene_name": "SNF2", "gene_names_uniprotkb": "SNF2; GAM1; RIC1; SWI2; TYE3", "gene_names_refseq": "GAM1; HAF1; SNF2; SWI2; TYE3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NAPLDSKDENFASVSPAGPS", "down_seq": "VHNAKNGTLDKNSQTVSGTP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816" }, { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser364" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "151", "end_pos": "151" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "390", "end_pos": "390" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1340", "end_pos": "1340" }, { "start_pos": "1375", "end_pos": "1375" }, { "start_pos": "1422", "end_pos": "1422" }, { "start_pos": "1429", "end_pos": "1429" }, { "start_pos": "1470", "end_pos": "1470" }, { "start_pos": "1471", "end_pos": "1471" }, { "start_pos": "1474", "end_pos": "1474" }, { "start_pos": "1478", "end_pos": "1478" }, { "start_pos": "1480", "end_pos": "1480" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "1541", "end_pos": "1541" }, { "start_pos": "1542", "end_pos": "1542" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "364", "end_pos": "364" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "611", "end_pos": "611" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "745", "end_pos": "745" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "P22082-1.356.356", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P22082-1.358.358", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P22082-1.377.377", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P22082-1.381.381", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P22082-1.383.383", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22082-1.383.383", "start_pos": 383, "end_pos": 383, "uniprot_canonical_ac": "P22082-1", "length": 1703, "uniprot_id": "SNF2_YEAST", "protein_name": "SWI/SNF chromatin-remodeling complex subunit SNF2", "refseq_ac": "NP_014933", "refseq_name": "SWI/SNF catalytic subunit SNF2", "gene_name": "SNF2", "gene_names_uniprotkb": "SNF2; GAM1; RIC1; SWI2; TYE3", "gene_names_refseq": "GAM1; HAF1; SNF2; SWI2; TYE3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" }, { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SSVHNAKNGTLDKNSQTVSG", "down_seq": "PITQTESKKEENETISNVAK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" }, { "database": "SGD", "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr383" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "151", "end_pos": "151" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "390", "end_pos": "390" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1340", "end_pos": "1340" }, { "start_pos": "1375", "end_pos": "1375" }, { "start_pos": "1422", "end_pos": "1422" }, { "start_pos": "1429", "end_pos": "1429" }, { "start_pos": "1470", "end_pos": "1470" }, { "start_pos": "1471", "end_pos": "1471" }, { "start_pos": "1474", "end_pos": "1474" }, { "start_pos": "1478", "end_pos": "1478" }, { "start_pos": "1480", "end_pos": "1480" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "1541", "end_pos": "1541" }, { "start_pos": "1542", "end_pos": "1542" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "364", "end_pos": "364" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "611", "end_pos": "611" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "745", "end_pos": "745" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P22082-1.364.364", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P22082-1.377.377", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P22082-1.381.381", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P22082-1.390.390", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22082-1.611.611", "start_pos": 611, "end_pos": 611, "uniprot_canonical_ac": "P22082-1", "length": 1703, "uniprot_id": "SNF2_YEAST", "protein_name": "SWI/SNF chromatin-remodeling complex subunit SNF2", "refseq_ac": "NP_014933", "refseq_name": "SWI/SNF catalytic subunit SNF2", "gene_name": "SNF2", "gene_names_uniprotkb": "SNF2; GAM1; RIC1; SWI2; TYE3", "gene_names_refseq": "GAM1; HAF1; SNF2; SWI2; TYE3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "crossref": [ { "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LLKLERKKTEAVARLKSMNK", "down_seq": "AINQYNRRQDKKNKRLKFGH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816" }, { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Ser611" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "151", "end_pos": "151" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "390", "end_pos": "390" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1340", "end_pos": "1340" }, { "start_pos": "1375", "end_pos": "1375" }, { "start_pos": "1422", "end_pos": "1422" }, { "start_pos": "1429", "end_pos": "1429" }, { "start_pos": "1470", "end_pos": "1470" }, { "start_pos": "1471", "end_pos": "1471" }, { "start_pos": "1474", "end_pos": "1474" }, { "start_pos": "1478", "end_pos": "1478" }, { "start_pos": "1480", "end_pos": "1480" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "1541", "end_pos": "1541" }, { "start_pos": "1542", "end_pos": "1542" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "364", "end_pos": "364" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "611", "end_pos": "611" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "745", "end_pos": "745" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22082-1.692.692", "start_pos": 692, "end_pos": 692, "uniprot_canonical_ac": "P22082-1", "length": 1703, "uniprot_id": "SNF2_YEAST", "protein_name": "SWI/SNF chromatin-remodeling complex subunit SNF2", "refseq_ac": "NP_014933", "refseq_name": "SWI/SNF catalytic subunit SNF2", "gene_name": "SNF2", "gene_names_uniprotkb": "SNF2; GAM1; RIC1; SWI2; TYE3", "gene_names_refseq": "GAM1; HAF1; SNF2; SWI2; TYE3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DQTKDTRITHLLRQTNAFLD", "down_seq": "LTRAVKDQQKYTKEMIDSHI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816" }, { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser692" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "151", "end_pos": "151" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "390", "end_pos": "390" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1340", "end_pos": "1340" }, { "start_pos": "1375", "end_pos": "1375" }, { "start_pos": "1422", "end_pos": "1422" }, { "start_pos": "1429", "end_pos": "1429" }, { "start_pos": "1470", "end_pos": "1470" }, { "start_pos": "1471", "end_pos": "1471" }, { "start_pos": "1474", "end_pos": "1474" }, { "start_pos": "1478", "end_pos": "1478" }, { "start_pos": "1480", "end_pos": "1480" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "1541", "end_pos": "1541" }, { "start_pos": "1542", "end_pos": "1542" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "364", "end_pos": "364" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "611", "end_pos": "611" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "745", "end_pos": "745" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "upstream", "id": "P22082-1.710.710", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22082-1.710.710", "start_pos": 710, "end_pos": 710, "uniprot_canonical_ac": "P22082-1", "length": 1703, "uniprot_id": "SNF2_YEAST", "protein_name": "SWI/SNF chromatin-remodeling complex subunit SNF2", "refseq_ac": "NP_014933", "refseq_name": "SWI/SNF catalytic subunit SNF2", "gene_name": "SNF2", "gene_names_uniprotkb": "SNF2; GAM1; RIC1; SWI2; TYE3", "gene_names_refseq": "GAM1; HAF1; SNF2; SWI2; TYE3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" }, { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast.", "journal": "Proteomics", "date": "2009-10", "authors": "Gnad Florian, de Godoy Lyris M F, Cox J\u00fcrgen, Neuhauser Nadin, Ren Shubin, Olsen Jesper V, Mann Matthias", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" } ] }, { "title": "Global analysis of the yeast osmotic stress response by quantitative proteomics.", "journal": "Molecular bioSystems", "date": "2009-11", "authors": "Soufi Boumediene, Kelstrup Christian D, Stoehr Gabriele, Fr\u00f6hlich Florian, Walther Tobias C, Olsen Jesper V", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LDSLTRAVKDQQKYTKEMID", "down_seq": "HIKEASEEVDDLSMVPKMKD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser710" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "151", "end_pos": "151" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "390", "end_pos": "390" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1340", "end_pos": "1340" }, { "start_pos": "1375", "end_pos": "1375" }, { "start_pos": "1422", "end_pos": "1422" }, { "start_pos": "1429", "end_pos": "1429" }, { "start_pos": "1470", "end_pos": "1470" }, { "start_pos": "1471", "end_pos": "1471" }, { "start_pos": "1474", "end_pos": "1474" }, { "start_pos": "1478", "end_pos": "1478" }, { "start_pos": "1480", "end_pos": "1480" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "1541", "end_pos": "1541" }, { "start_pos": "1542", "end_pos": "1542" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "364", "end_pos": "364" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "611", "end_pos": "611" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "745", "end_pos": "745" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P22082-1.692.692", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P22082-1.716.716", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22082-1.716.716", "start_pos": 716, "end_pos": 716, "uniprot_canonical_ac": "P22082-1", "length": 1703, "uniprot_id": "SNF2_YEAST", "protein_name": "SWI/SNF chromatin-remodeling complex subunit SNF2", "refseq_ac": "NP_014933", "refseq_name": "SWI/SNF catalytic subunit SNF2", "gene_name": "SNF2", "gene_names_uniprotkb": "SNF2; GAM1; RIC1; SWI2; TYE3", "gene_names_refseq": "GAM1; HAF1; SNF2; SWI2; TYE3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" }, { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" }, { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AVKDQQKYTKEMIDSHIKEA", "down_seq": "EEVDDLSMVPKMKDEEYDDD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" }, { "database": "SGD", "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser716" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "151", "end_pos": "151" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "390", "end_pos": "390" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1340", "end_pos": "1340" }, { "start_pos": "1375", "end_pos": "1375" }, { "start_pos": "1422", "end_pos": "1422" }, { "start_pos": "1429", "end_pos": "1429" }, { "start_pos": "1470", "end_pos": "1470" }, { "start_pos": "1471", "end_pos": "1471" }, { "start_pos": "1474", "end_pos": "1474" }, { "start_pos": "1478", "end_pos": "1478" }, { "start_pos": "1480", "end_pos": "1480" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "1541", "end_pos": "1541" }, { "start_pos": "1542", "end_pos": "1542" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "364", "end_pos": "364" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "611", "end_pos": "611" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "745", "end_pos": "745" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "P22082-1.710.710", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22082-1.745.745", "start_pos": 745, "end_pos": 745, "uniprot_canonical_ac": "P22082-1", "length": 1703, "uniprot_id": "SNF2_YEAST", "protein_name": "SWI/SNF chromatin-remodeling complex subunit SNF2", "refseq_ac": "NP_014933", "refseq_name": "SWI/SNF catalytic subunit SNF2", "gene_name": "SNF2", "gene_names_uniprotkb": "SNF2; GAM1; RIC1; SWI2; TYE3", "gene_names_refseq": "GAM1; HAF1; SNF2; SWI2; TYE3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22082", "url": "https://www.uniprot.org/uniprotkb/P22082" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cell cycle phosphorylation of mitotic exit network (MEN) proteins.", "journal": "Cell cycle (Georgetown, Tex.)", "date": "2011-10-15", "authors": "Jones Michele H, Keck Jamie M, Wong Catherine C L, Xu Tao, Yates John R, Winey Mark", "evidence": [ { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" } ], "reference": [ { "type": "PubMed", "id": "22031224", "url": "https://glygen.org/publication/PubMed/22031224" } ] } ], "crossref": [ { "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "22031224", "url": "https://glygen.org/publication/PubMed/22031224", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "VPKMKDEEYDDDDDNSNVDY", "down_seq": "NVAHRIKEDIKKQPSILVGG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005816", "url": "https://www.yeastgenome.org/locus/S000005816" }, { "database": "iPTMnet", "id": "P22082", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22082" }, { "database": "PubMed", "id": "22031224", "url": "https://glygen.org/publication/PubMed/22031224" } ], "site_lbl": "Tyr745" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "151", "end_pos": "151" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "390", "end_pos": "390" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1340", "end_pos": "1340" }, { "start_pos": "1375", "end_pos": "1375" }, { "start_pos": "1422", "end_pos": "1422" }, { "start_pos": "1429", "end_pos": "1429" }, { "start_pos": "1470", "end_pos": "1470" }, { "start_pos": "1471", "end_pos": "1471" }, { "start_pos": "1474", "end_pos": "1474" }, { "start_pos": "1478", "end_pos": "1478" }, { "start_pos": "1480", "end_pos": "1480" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "1541", "end_pos": "1541" }, { "start_pos": "1542", "end_pos": "1542" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "364", "end_pos": "364" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "383", "end_pos": "383" }, { "start_pos": "611", "end_pos": "611" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "710", "end_pos": "710" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "745", "end_pos": "745" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22138-1.677.677", "start_pos": 677, "end_pos": 677, "uniprot_canonical_ac": "P22138-1", "length": 1203, "uniprot_id": "RPA2_YEAST", "protein_name": "DNA-directed RNA polymerase I subunit RPA135", "refseq_ac": "NP_015335", "refseq_name": "DNA-directed RNA polymerase I core subunit RPA135", "gene_name": "RPA135", "gene_names_uniprotkb": "RPA135; RPA2; RRN2; SRP3; YP9531.03C", "gene_names_refseq": "RPA135; RPA2; RRN2; SRP3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [], "crossref": [ { "id": "GLY_001160", "url": "https://data.glygen.org/GLY_001160", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PLDKEDIVGPFEQVYMNIAV", "down_seq": "PQEIQNNVHTHVEFTPTNIL", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr677", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "677", "end_pos": "677" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1104", "end_pos": "1104" }, { "start_pos": "1107", "end_pos": "1107" }, { "start_pos": "1127", "end_pos": "1127" }, { "start_pos": "1128", "end_pos": "1128" }, { "start_pos": "1131", "end_pos": "1131" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1049", "end_pos": "1049" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "1122", "end_pos": "1122" }, { "start_pos": "1124", "end_pos": "1124" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "1156", "end_pos": "1156" }, { "start_pos": "115", "end_pos": "115" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "86", "end_pos": "86" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P22138-1.1104.1104", "start_pos": 1104, "end_pos": 1104, "uniprot_canonical_ac": "P22138-1", "length": 1203, "uniprot_id": "RPA2_YEAST", "protein_name": "DNA-directed RNA polymerase I subunit RPA135", "refseq_ac": "NP_015335", "refseq_name": "DNA-directed RNA polymerase I core subunit RPA135", "gene_name": "RPA135", "gene_names_uniprotkb": "RPA135; RPA2; RRN2; SRP3; YP9531.03C", "gene_names_refseq": "RPA135; RPA2; RRN2; SRP3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Role of second-largest RNA polymerase I subunit Zn-binding domain in enzyme assembly.", "journal": "Eukaryotic cell", "date": "2003-10", "authors": "Naryshkina Tatyana, Bruning Adrian, Gadal Olivier, Severinov Konstantin", "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" } ], "reference": [ { "type": "PubMed", "id": "14555487", "url": "https://glygen.org/publication/PubMed/14555487" } ] } ], "crossref": [ { "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "14555487", "url": "https://glygen.org/publication/PubMed/14555487", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "TSFLLQDRLLNSSDYTQASV", "down_seq": "RECGSILTTQQSVPRIGSIS", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "No effect; when associated with A-1107; A-1128 and A-1131.", "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" }, { "database": "PubMed", "id": "14555487", "url": "https://glygen.org/publication/PubMed/14555487" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "677", "end_pos": "677" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1104", "end_pos": "1104" }, { "start_pos": "1107", "end_pos": "1107" }, { "start_pos": "1127", "end_pos": "1127" }, { "start_pos": "1128", "end_pos": "1128" }, { "start_pos": "1131", "end_pos": "1131" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1049", "end_pos": "1049" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "1122", "end_pos": "1122" }, { "start_pos": "1124", "end_pos": "1124" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "1156", "end_pos": "1156" }, { "start_pos": "115", "end_pos": "115" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "86", "end_pos": "86" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P22138-1.1085.1085", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P22138-1.1107.1107", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P22138-1.1116.1116", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P22138-1.1122.1122", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P22138-1.1124.1124", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22138-1.1107.1107", "start_pos": 1107, "end_pos": 1107, "uniprot_canonical_ac": "P22138-1", "length": 1203, "uniprot_id": "RPA2_YEAST", "protein_name": "DNA-directed RNA polymerase I subunit RPA135", "refseq_ac": "NP_015335", "refseq_name": "DNA-directed RNA polymerase I core subunit RPA135", "gene_name": "RPA135", "gene_names_uniprotkb": "RPA135; RPA2; RRN2; SRP3; YP9531.03C", "gene_names_refseq": "RPA135; RPA2; RRN2; SRP3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Role of second-largest RNA polymerase I subunit Zn-binding domain in enzyme assembly.", "journal": "Eukaryotic cell", "date": "2003-10", "authors": "Naryshkina Tatyana, Bruning Adrian, Gadal Olivier, Severinov Konstantin", "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" } ], "reference": [ { "type": "PubMed", "id": "14555487", "url": "https://glygen.org/publication/PubMed/14555487" } ] } ], "crossref": [ { "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "14555487", "url": "https://glygen.org/publication/PubMed/14555487", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "LLQDRLLNSSDYTQASVCRE", "down_seq": "GSILTTQQSVPRIGSISTVC", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Lethal. Abolishes recruitment of RPA1 to Pol I. No effect; when associated with A-1104; A-1128 and A-1131.", "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" }, { "database": "PubMed", "id": "14555487", "url": "https://glygen.org/publication/PubMed/14555487" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "677", "end_pos": "677" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1104", "end_pos": "1104" }, { "start_pos": "1107", "end_pos": "1107" }, { "start_pos": "1127", "end_pos": "1127" }, { "start_pos": "1128", "end_pos": "1128" }, { "start_pos": "1131", "end_pos": "1131" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1049", "end_pos": "1049" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "1122", "end_pos": "1122" }, { "start_pos": "1124", "end_pos": "1124" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "1156", "end_pos": "1156" }, { "start_pos": "115", "end_pos": "115" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "86", "end_pos": "86" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P22138-1.1104.1104", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P22138-1.1116.1116", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P22138-1.1122.1122", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P22138-1.1124.1124", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P22138-1.1127.1127", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22138-1.1127.1127", "start_pos": 1127, "end_pos": 1127, "uniprot_canonical_ac": "P22138-1", "length": 1203, "uniprot_id": "RPA2_YEAST", "protein_name": "DNA-directed RNA polymerase I subunit RPA135", "refseq_ac": "NP_015335", "refseq_name": "DNA-directed RNA polymerase I core subunit RPA135", "gene_name": "RPA135", "gene_names_uniprotkb": "RPA135; RPA2; RRN2; SRP3; YP9531.03C", "gene_names_refseq": "RPA135; RPA2; RRN2; SRP3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [], "crossref": [ { "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "CGSILTTQQSVPRIGSISTV", "down_seq": "CRRCSMRFEDAKKLLTKSED", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "R", "comment": "Responsible of suppression of RPA190-5 and RPA190-1 mutations.", "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "677", "end_pos": "677" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1104", "end_pos": "1104" }, { "start_pos": "1107", "end_pos": "1107" }, { "start_pos": "1127", "end_pos": "1127" }, { "start_pos": "1128", "end_pos": "1128" }, { "start_pos": "1131", "end_pos": "1131" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1049", "end_pos": "1049" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "1122", "end_pos": "1122" }, { "start_pos": "1124", "end_pos": "1124" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "1156", "end_pos": "1156" }, { "start_pos": "115", "end_pos": "115" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "86", "end_pos": "86" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P22138-1.1107.1107", "categories": [ "mutagenesis_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P22138-1.1116.1116", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P22138-1.1122.1122", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P22138-1.1124.1124", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P22138-1.1128.1128", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P22138-1.1131.1131", "categories": [ "mutagenesis_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P22138-1.1145.1145", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P22138-1.1128.1128", "start_pos": 1128, "end_pos": 1128, "uniprot_canonical_ac": "P22138-1", "length": 1203, "uniprot_id": "RPA2_YEAST", "protein_name": "DNA-directed RNA polymerase I subunit RPA135", "refseq_ac": "NP_015335", "refseq_name": "DNA-directed RNA polymerase I core subunit RPA135", "gene_name": "RPA135", "gene_names_uniprotkb": "RPA135; RPA2; RRN2; SRP3; YP9531.03C", "gene_names_refseq": "RPA135; RPA2; RRN2; SRP3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Role of second-largest RNA polymerase I subunit Zn-binding domain in enzyme assembly.", "journal": "Eukaryotic cell", "date": "2003-10", "authors": "Naryshkina Tatyana, Bruning Adrian, Gadal Olivier, Severinov Konstantin", "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" } ], "reference": [ { "type": "PubMed", "id": "14555487", "url": "https://glygen.org/publication/PubMed/14555487" } ] } ], "crossref": [ { "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "14555487", "url": "https://glygen.org/publication/PubMed/14555487", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "GSILTTQQSVPRIGSISTVC", "down_seq": "RRCSMRFEDAKKLLTKSEDG", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "No effect; when associated with A-1104; A-1107 and A-1131.", "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" }, { "database": "PubMed", "id": "14555487", "url": "https://glygen.org/publication/PubMed/14555487" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "677", "end_pos": "677" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1104", "end_pos": "1104" }, { "start_pos": "1107", "end_pos": "1107" }, { "start_pos": "1127", "end_pos": "1127" }, { "start_pos": "1128", "end_pos": "1128" }, { "start_pos": "1131", "end_pos": "1131" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1049", "end_pos": "1049" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "1122", "end_pos": "1122" }, { "start_pos": "1124", "end_pos": "1124" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "1156", "end_pos": "1156" }, { "start_pos": "115", "end_pos": "115" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "86", "end_pos": "86" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P22138-1.1116.1116", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P22138-1.1122.1122", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P22138-1.1124.1124", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P22138-1.1127.1127", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P22138-1.1131.1131", "categories": [ "mutagenesis_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P22138-1.1145.1145", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22138-1.1131.1131", "start_pos": 1131, "end_pos": 1131, "uniprot_canonical_ac": "P22138-1", "length": 1203, "uniprot_id": "RPA2_YEAST", "protein_name": "DNA-directed RNA polymerase I subunit RPA135", "refseq_ac": "NP_015335", "refseq_name": "DNA-directed RNA polymerase I core subunit RPA135", "gene_name": "RPA135", "gene_names_uniprotkb": "RPA135; RPA2; RRN2; SRP3; YP9531.03C", "gene_names_refseq": "RPA135; RPA2; RRN2; SRP3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Role of second-largest RNA polymerase I subunit Zn-binding domain in enzyme assembly.", "journal": "Eukaryotic cell", "date": "2003-10", "authors": "Naryshkina Tatyana, Bruning Adrian, Gadal Olivier, Severinov Konstantin", "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" } ], "reference": [ { "type": "PubMed", "id": "14555487", "url": "https://glygen.org/publication/PubMed/14555487" } ] } ], "crossref": [ { "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "14555487", "url": "https://glygen.org/publication/PubMed/14555487", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "LTTQQSVPRIGSISTVCCRR", "down_seq": "SMRFEDAKKLLTKSEDGEKI", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "No effect; when associated with A-1104; A-1107 and A-1128.", "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" }, { "database": "PubMed", "id": "14555487", "url": "https://glygen.org/publication/PubMed/14555487" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "677", "end_pos": "677" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1104", "end_pos": "1104" }, { "start_pos": "1107", "end_pos": "1107" }, { "start_pos": "1127", "end_pos": "1127" }, { "start_pos": "1128", "end_pos": "1128" }, { "start_pos": "1131", "end_pos": "1131" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1049", "end_pos": "1049" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "1122", "end_pos": "1122" }, { "start_pos": "1124", "end_pos": "1124" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "1156", "end_pos": "1156" }, { "start_pos": "115", "end_pos": "115" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "86", "end_pos": "86" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P22138-1.1116.1116", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P22138-1.1122.1122", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P22138-1.1124.1124", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P22138-1.1127.1127", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P22138-1.1128.1128", "categories": [ "mutagenesis_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P22138-1.1145.1145", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22138-1.1049.1049", "start_pos": 1049, "end_pos": 1049, "uniprot_canonical_ac": "P22138-1", "length": 1203, "uniprot_id": "RPA2_YEAST", "protein_name": "DNA-directed RNA polymerase I subunit RPA135", "refseq_ac": "NP_015335", "refseq_name": "DNA-directed RNA polymerase I core subunit RPA135", "gene_name": "RPA135", "gene_names_uniprotkb": "RPA135; RPA2; RRN2; SRP3; YP9531.03C", "gene_names_refseq": "RPA135; RPA2; RRN2; SRP3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000006214", "url": "https://www.yeastgenome.org/locus/S000006214", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "GVVYYQRLRHMVNDKFQVRS", "down_seq": "GPVNSLTMQPVKGRKRHGGI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006214", "url": "https://www.yeastgenome.org/locus/S000006214" }, { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr1049" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "677", "end_pos": "677" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1104", "end_pos": "1104" }, { "start_pos": "1107", "end_pos": "1107" }, { "start_pos": "1127", "end_pos": "1127" }, { "start_pos": "1128", "end_pos": "1128" }, { "start_pos": "1131", "end_pos": "1131" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1049", "end_pos": "1049" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "1122", "end_pos": "1122" }, { "start_pos": "1124", "end_pos": "1124" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "1156", "end_pos": "1156" }, { "start_pos": "115", "end_pos": "115" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "86", "end_pos": "86" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "upstream", "id": "P22138-1.1054.1054", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22138-1.1054.1054", "start_pos": 1054, "end_pos": 1054, "uniprot_canonical_ac": "P22138-1", "length": 1203, "uniprot_id": "RPA2_YEAST", "protein_name": "DNA-directed RNA polymerase I subunit RPA135", "refseq_ac": "NP_015335", "refseq_name": "DNA-directed RNA polymerase I core subunit RPA135", "gene_name": "RPA135", "gene_names_uniprotkb": "RPA135; RPA2; RRN2; SRP3; YP9531.03C", "gene_names_refseq": "RPA135; RPA2; RRN2; SRP3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006214", "url": "https://www.yeastgenome.org/locus/S000006214", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QRLRHMVNDKFQVRSTGPVN", "down_seq": "LTMQPVKGRKRHGGIRVGEM", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006214", "url": "https://www.yeastgenome.org/locus/S000006214" }, { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1054" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "677", "end_pos": "677" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1104", "end_pos": "1104" }, { "start_pos": "1107", "end_pos": "1107" }, { "start_pos": "1127", "end_pos": "1127" }, { "start_pos": "1128", "end_pos": "1128" }, { "start_pos": "1131", "end_pos": "1131" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1049", "end_pos": "1049" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "1122", "end_pos": "1122" }, { "start_pos": "1124", "end_pos": "1124" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "1156", "end_pos": "1156" }, { "start_pos": "115", "end_pos": "115" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "86", "end_pos": "86" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "P22138-1.1049.1049", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22138-1.1085.1085", "start_pos": 1085, "end_pos": 1085, "uniprot_canonical_ac": "P22138-1", "length": 1203, "uniprot_id": "RPA2_YEAST", "protein_name": "DNA-directed RNA polymerase I subunit RPA135", "refseq_ac": "NP_015335", "refseq_name": "DNA-directed RNA polymerase I core subunit RPA135", "gene_name": "RPA135", "gene_names_uniprotkb": "RPA135; RPA2; RRN2; SRP3; YP9531.03C", "gene_names_refseq": "RPA135; RPA2; RRN2; SRP3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" }, { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000006214", "url": "https://www.yeastgenome.org/locus/S000006214", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RHGGIRVGEMERDALIGHGT", "down_seq": "FLLQDRLLNSSDYTQASVCR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000006214", "url": "https://www.yeastgenome.org/locus/S000006214" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1085" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "677", "end_pos": "677" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1104", "end_pos": "1104" }, { "start_pos": "1107", "end_pos": "1107" }, { "start_pos": "1127", "end_pos": "1127" }, { "start_pos": "1128", "end_pos": "1128" }, { "start_pos": "1131", "end_pos": "1131" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1049", "end_pos": "1049" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "1122", "end_pos": "1122" }, { "start_pos": "1124", "end_pos": "1124" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "1156", "end_pos": "1156" }, { "start_pos": "115", "end_pos": "115" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "86", "end_pos": "86" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "upstream", "id": "P22138-1.1104.1104", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22138-1.1116.1116", "start_pos": 1116, "end_pos": 1116, "uniprot_canonical_ac": "P22138-1", "length": 1203, "uniprot_id": "RPA2_YEAST", "protein_name": "DNA-directed RNA polymerase I subunit RPA135", "refseq_ac": "NP_015335", "refseq_name": "DNA-directed RNA polymerase I core subunit RPA135", "gene_name": "RPA135", "gene_names_uniprotkb": "RPA135; RPA2; RRN2; SRP3; YP9531.03C", "gene_names_refseq": "RPA135; RPA2; RRN2; SRP3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" }, { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000006214", "url": "https://www.yeastgenome.org/locus/S000006214", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SDYTQASVCRECGSILTTQQ", "down_seq": "VPRIGSISTVCCRRCSMRFE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000006214", "url": "https://www.yeastgenome.org/locus/S000006214" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1116" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "677", "end_pos": "677" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1104", "end_pos": "1104" }, { "start_pos": "1107", "end_pos": "1107" }, { "start_pos": "1127", "end_pos": "1127" }, { "start_pos": "1128", "end_pos": "1128" }, { "start_pos": "1131", "end_pos": "1131" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1049", "end_pos": "1049" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "1122", "end_pos": "1122" }, { "start_pos": "1124", "end_pos": "1124" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "1156", "end_pos": "1156" }, { "start_pos": "115", "end_pos": "115" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "86", "end_pos": "86" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P22138-1.1104.1104", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P22138-1.1107.1107", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P22138-1.1122.1122", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P22138-1.1124.1124", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P22138-1.1127.1127", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P22138-1.1128.1128", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P22138-1.1131.1131", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22138-1.1122.1122", "start_pos": 1122, "end_pos": 1122, "uniprot_canonical_ac": "P22138-1", "length": 1203, "uniprot_id": "RPA2_YEAST", "protein_name": "DNA-directed RNA polymerase I subunit RPA135", "refseq_ac": "NP_015335", "refseq_name": "DNA-directed RNA polymerase I core subunit RPA135", "gene_name": "RPA135", "gene_names_uniprotkb": "RPA135; RPA2; RRN2; SRP3; YP9531.03C", "gene_names_refseq": "RPA135; RPA2; RRN2; SRP3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006214", "url": "https://www.yeastgenome.org/locus/S000006214", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SVCRECGSILTTQQSVPRIG", "down_seq": "ISTVCCRRCSMRFEDAKKLL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006214", "url": "https://www.yeastgenome.org/locus/S000006214" }, { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1122" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "677", "end_pos": "677" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1104", "end_pos": "1104" }, { "start_pos": "1107", "end_pos": "1107" }, { "start_pos": "1127", "end_pos": "1127" }, { "start_pos": "1128", "end_pos": "1128" }, { "start_pos": "1131", "end_pos": "1131" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1049", "end_pos": "1049" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "1122", "end_pos": "1122" }, { "start_pos": "1124", "end_pos": "1124" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "1156", "end_pos": "1156" }, { "start_pos": "115", "end_pos": "115" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "86", "end_pos": "86" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P22138-1.1104.1104", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P22138-1.1107.1107", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P22138-1.1116.1116", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P22138-1.1124.1124", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P22138-1.1127.1127", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P22138-1.1128.1128", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P22138-1.1131.1131", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22138-1.1124.1124", "start_pos": 1124, "end_pos": 1124, "uniprot_canonical_ac": "P22138-1", "length": 1203, "uniprot_id": "RPA2_YEAST", "protein_name": "DNA-directed RNA polymerase I subunit RPA135", "refseq_ac": "NP_015335", "refseq_name": "DNA-directed RNA polymerase I core subunit RPA135", "gene_name": "RPA135", "gene_names_uniprotkb": "RPA135; RPA2; RRN2; SRP3; YP9531.03C", "gene_names_refseq": "RPA135; RPA2; RRN2; SRP3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006214", "url": "https://www.yeastgenome.org/locus/S000006214", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "CRECGSILTTQQSVPRIGSI", "down_seq": "TVCCRRCSMRFEDAKKLLTK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006214", "url": "https://www.yeastgenome.org/locus/S000006214" }, { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1124" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "677", "end_pos": "677" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1104", "end_pos": "1104" }, { "start_pos": "1107", "end_pos": "1107" }, { "start_pos": "1127", "end_pos": "1127" }, { "start_pos": "1128", "end_pos": "1128" }, { "start_pos": "1131", "end_pos": "1131" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1049", "end_pos": "1049" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "1122", "end_pos": "1122" }, { "start_pos": "1124", "end_pos": "1124" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "1156", "end_pos": "1156" }, { "start_pos": "115", "end_pos": "115" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "86", "end_pos": "86" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P22138-1.1104.1104", "categories": [ "mutagenesis_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P22138-1.1107.1107", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P22138-1.1116.1116", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P22138-1.1122.1122", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P22138-1.1127.1127", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P22138-1.1128.1128", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P22138-1.1131.1131", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22138-1.1145.1145", "start_pos": 1145, "end_pos": 1145, "uniprot_canonical_ac": "P22138-1", "length": 1203, "uniprot_id": "RPA2_YEAST", "protein_name": "DNA-directed RNA polymerase I subunit RPA135", "refseq_ac": "NP_015335", "refseq_name": "DNA-directed RNA polymerase I core subunit RPA135", "gene_name": "RPA135", "gene_names_uniprotkb": "RPA135; RPA2; RRN2; SRP3; YP9531.03C", "gene_names_refseq": "RPA135; RPA2; RRN2; SRP3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006214", "url": "https://www.yeastgenome.org/locus/S000006214", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TVCCRRCSMRFEDAKKLLTK", "down_seq": "EDGEKIFIDDSQIWEDGQGN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006214", "url": "https://www.yeastgenome.org/locus/S000006214" }, { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1145" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "677", "end_pos": "677" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1104", "end_pos": "1104" }, { "start_pos": "1107", "end_pos": "1107" }, { "start_pos": "1127", "end_pos": "1127" }, { "start_pos": "1128", "end_pos": "1128" }, { "start_pos": "1131", "end_pos": "1131" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1049", "end_pos": "1049" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "1122", "end_pos": "1122" }, { "start_pos": "1124", "end_pos": "1124" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "1156", "end_pos": "1156" }, { "start_pos": "115", "end_pos": "115" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "86", "end_pos": "86" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P22138-1.1127.1127", "categories": [ "mutagenesis_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P22138-1.1128.1128", "categories": [ "mutagenesis_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P22138-1.1131.1131", "categories": [ "mutagenesis_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P22138-1.1156.1156", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22138-1.1156.1156", "start_pos": 1156, "end_pos": 1156, "uniprot_canonical_ac": "P22138-1", "length": 1203, "uniprot_id": "RPA2_YEAST", "protein_name": "DNA-directed RNA polymerase I subunit RPA135", "refseq_ac": "NP_015335", "refseq_name": "DNA-directed RNA polymerase I core subunit RPA135", "gene_name": "RPA135", "gene_names_uniprotkb": "RPA135; RPA2; RRN2; SRP3; YP9531.03C", "gene_names_refseq": "RPA135; RPA2; RRN2; SRP3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" }, { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000006214", "url": "https://www.yeastgenome.org/locus/S000006214", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EDAKKLLTKSEDGEKIFIDD", "down_seq": "QIWEDGQGNKFVGGNETTTV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" }, { "database": "SGD", "id": "S000006214", "url": "https://www.yeastgenome.org/locus/S000006214" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1156" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "677", "end_pos": "677" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1104", "end_pos": "1104" }, { "start_pos": "1107", "end_pos": "1107" }, { "start_pos": "1127", "end_pos": "1127" }, { "start_pos": "1128", "end_pos": "1128" }, { "start_pos": "1131", "end_pos": "1131" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1049", "end_pos": "1049" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "1122", "end_pos": "1122" }, { "start_pos": "1124", "end_pos": "1124" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "1156", "end_pos": "1156" }, { "start_pos": "115", "end_pos": "115" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "86", "end_pos": "86" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P22138-1.1145.1145", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22138-1.115.115", "start_pos": 115, "end_pos": 115, "uniprot_canonical_ac": "P22138-1", "length": 1203, "uniprot_id": "RPA2_YEAST", "protein_name": "DNA-directed RNA polymerase I subunit RPA135", "refseq_ac": "NP_015335", "refseq_name": "DNA-directed RNA polymerase I core subunit RPA135", "gene_name": "RPA135", "gene_names_uniprotkb": "RPA135; RPA2; RRN2; SRP3; YP9531.03C", "gene_names_refseq": "RPA135; RPA2; RRN2; SRP3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006214", "url": "https://www.yeastgenome.org/locus/S000006214", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LSVSVEQVSIAKPMSNDGVS", "down_seq": "AVERKVYPSESRQRLTSYRG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006214", "url": "https://www.yeastgenome.org/locus/S000006214" }, { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser115" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "677", "end_pos": "677" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1104", "end_pos": "1104" }, { "start_pos": "1107", "end_pos": "1107" }, { "start_pos": "1127", "end_pos": "1127" }, { "start_pos": "1128", "end_pos": "1128" }, { "start_pos": "1131", "end_pos": "1131" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1049", "end_pos": "1049" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "1122", "end_pos": "1122" }, { "start_pos": "1124", "end_pos": "1124" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "1156", "end_pos": "1156" }, { "start_pos": "115", "end_pos": "115" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "86", "end_pos": "86" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22138-1.507.507", "start_pos": 507, "end_pos": 507, "uniprot_canonical_ac": "P22138-1", "length": 1203, "uniprot_id": "RPA2_YEAST", "protein_name": "DNA-directed RNA polymerase I subunit RPA135", "refseq_ac": "NP_015335", "refseq_name": "DNA-directed RNA polymerase I core subunit RPA135", "gene_name": "RPA135", "gene_names_uniprotkb": "RPA135; RPA2; RRN2; SRP3; YP9531.03C", "gene_names_refseq": "RPA135; RPA2; RRN2; SRP3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006214", "url": "https://www.yeastgenome.org/locus/S000006214", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VAEKINFYRFISHFRMVHRG", "down_seq": "FFAQLKTTTVRKLLPESWGF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006214", "url": "https://www.yeastgenome.org/locus/S000006214" }, { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser507" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "677", "end_pos": "677" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1104", "end_pos": "1104" }, { "start_pos": "1107", "end_pos": "1107" }, { "start_pos": "1127", "end_pos": "1127" }, { "start_pos": "1128", "end_pos": "1128" }, { "start_pos": "1131", "end_pos": "1131" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1049", "end_pos": "1049" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "1122", "end_pos": "1122" }, { "start_pos": "1124", "end_pos": "1124" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "1156", "end_pos": "1156" }, { "start_pos": "115", "end_pos": "115" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "86", "end_pos": "86" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22138-1.712.712", "start_pos": 712, "end_pos": 712, "uniprot_canonical_ac": "P22138-1", "length": 1203, "uniprot_id": "RPA2_YEAST", "protein_name": "DNA-directed RNA polymerase I subunit RPA135", "refseq_ac": "NP_015335", "refseq_name": "DNA-directed RNA polymerase I core subunit RPA135", "gene_name": "RPA135", "gene_names_uniprotkb": "RPA135; RPA2; RRN2; SRP3; YP9531.03C", "gene_names_refseq": "RPA135; RPA2; RRN2; SRP3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006214", "url": "https://www.yeastgenome.org/locus/S000006214", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TPTNILSILANLTPFSDFNQ", "down_seq": "PRNMYQCQMGKQTMGTPGVA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006214", "url": "https://www.yeastgenome.org/locus/S000006214" }, { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser712" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "677", "end_pos": "677" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1104", "end_pos": "1104" }, { "start_pos": "1107", "end_pos": "1107" }, { "start_pos": "1127", "end_pos": "1127" }, { "start_pos": "1128", "end_pos": "1128" }, { "start_pos": "1131", "end_pos": "1131" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1049", "end_pos": "1049" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "1122", "end_pos": "1122" }, { "start_pos": "1124", "end_pos": "1124" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "1156", "end_pos": "1156" }, { "start_pos": "115", "end_pos": "115" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "86", "end_pos": "86" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22138-1.737.737", "start_pos": 737, "end_pos": 737, "uniprot_canonical_ac": "P22138-1", "length": 1203, "uniprot_id": "RPA2_YEAST", "protein_name": "DNA-directed RNA polymerase I subunit RPA135", "refseq_ac": "NP_015335", "refseq_name": "DNA-directed RNA polymerase I core subunit RPA135", "gene_name": "RPA135", "gene_names_uniprotkb": "RPA135; RPA2; RRN2; SRP3; YP9531.03C", "gene_names_refseq": "RPA135; RPA2; RRN2; SRP3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006214", "url": "https://www.yeastgenome.org/locus/S000006214", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "YQCQMGKQTMGTPGVALCHR", "down_seq": "DNKLYRLQTGQTPIVKANLY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006214", "url": "https://www.yeastgenome.org/locus/S000006214" }, { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser737" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "677", "end_pos": "677" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1104", "end_pos": "1104" }, { "start_pos": "1107", "end_pos": "1107" }, { "start_pos": "1127", "end_pos": "1127" }, { "start_pos": "1128", "end_pos": "1128" }, { "start_pos": "1131", "end_pos": "1131" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1049", "end_pos": "1049" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "1122", "end_pos": "1122" }, { "start_pos": "1124", "end_pos": "1124" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "1156", "end_pos": "1156" }, { "start_pos": "115", "end_pos": "115" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "86", "end_pos": "86" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "upstream", "id": "P22138-1.746.746", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22138-1.746.746", "start_pos": 746, "end_pos": 746, "uniprot_canonical_ac": "P22138-1", "length": 1203, "uniprot_id": "RPA2_YEAST", "protein_name": "DNA-directed RNA polymerase I subunit RPA135", "refseq_ac": "NP_015335", "refseq_name": "DNA-directed RNA polymerase I core subunit RPA135", "gene_name": "RPA135", "gene_names_uniprotkb": "RPA135; RPA2; RRN2; SRP3; YP9531.03C", "gene_names_refseq": "RPA135; RPA2; RRN2; SRP3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006214", "url": "https://www.yeastgenome.org/locus/S000006214", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "MGTPGVALCHRSDNKLYRLQ", "down_seq": "GQTPIVKANLYDDYGMDNFP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006214", "url": "https://www.yeastgenome.org/locus/S000006214" }, { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr746" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "677", "end_pos": "677" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1104", "end_pos": "1104" }, { "start_pos": "1107", "end_pos": "1107" }, { "start_pos": "1127", "end_pos": "1127" }, { "start_pos": "1128", "end_pos": "1128" }, { "start_pos": "1131", "end_pos": "1131" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1049", "end_pos": "1049" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "1122", "end_pos": "1122" }, { "start_pos": "1124", "end_pos": "1124" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "1156", "end_pos": "1156" }, { "start_pos": "115", "end_pos": "115" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "86", "end_pos": "86" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "P22138-1.737.737", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22138-1.81.81", "start_pos": 81, "end_pos": 81, "uniprot_canonical_ac": "P22138-1", "length": 1203, "uniprot_id": "RPA2_YEAST", "protein_name": "DNA-directed RNA polymerase I subunit RPA135", "refseq_ac": "NP_015335", "refseq_name": "DNA-directed RNA polymerase I core subunit RPA135", "gene_name": "RPA135", "gene_names_uniprotkb": "RPA135; RPA2; RRN2; SRP3; YP9531.03C", "gene_names_refseq": "RPA135; RPA2; RRN2; SRP3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" }, { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" }, { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-06-19", "authors": "Smolka Marcus B, Albuquerque Claudio P, Chen Sheng-hong, Zhou Huilin", "evidence": [ { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" } ], "reference": [ { "type": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000006214", "url": "https://www.yeastgenome.org/locus/S000006214", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LNLGVKDIGEKVIFDGKPLN", "down_seq": "EDEISNSGYLGNKLSVSVEQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000006214", "url": "https://www.yeastgenome.org/locus/S000006214" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser81" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "677", "end_pos": "677" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1104", "end_pos": "1104" }, { "start_pos": "1107", "end_pos": "1107" }, { "start_pos": "1127", "end_pos": "1127" }, { "start_pos": "1128", "end_pos": "1128" }, { "start_pos": "1131", "end_pos": "1131" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1049", "end_pos": "1049" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "1122", "end_pos": "1122" }, { "start_pos": "1124", "end_pos": "1124" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "1156", "end_pos": "1156" }, { "start_pos": "115", "end_pos": "115" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "86", "end_pos": "86" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "upstream", "id": "P22138-1.86.86", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P22138-1.88.88", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22138-1.86.86", "start_pos": 86, "end_pos": 86, "uniprot_canonical_ac": "P22138-1", "length": 1203, "uniprot_id": "RPA2_YEAST", "protein_name": "DNA-directed RNA polymerase I subunit RPA135", "refseq_ac": "NP_015335", "refseq_name": "DNA-directed RNA polymerase I core subunit RPA135", "gene_name": "RPA135", "gene_names_uniprotkb": "RPA135; RPA2; RRN2; SRP3; YP9531.03C", "gene_names_refseq": "RPA135; RPA2; RRN2; SRP3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000006214", "url": "https://www.yeastgenome.org/locus/S000006214", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KDIGEKVIFDGKPLNSEDEI", "down_seq": "NSGYLGNKLSVSVEQVSIAK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000006214", "url": "https://www.yeastgenome.org/locus/S000006214" }, { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser86" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "677", "end_pos": "677" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1104", "end_pos": "1104" }, { "start_pos": "1107", "end_pos": "1107" }, { "start_pos": "1127", "end_pos": "1127" }, { "start_pos": "1128", "end_pos": "1128" }, { "start_pos": "1131", "end_pos": "1131" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1049", "end_pos": "1049" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "1122", "end_pos": "1122" }, { "start_pos": "1124", "end_pos": "1124" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "1156", "end_pos": "1156" }, { "start_pos": "115", "end_pos": "115" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "86", "end_pos": "86" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "P22138-1.81.81", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P22138-1.88.88", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22138-1.88.88", "start_pos": 88, "end_pos": 88, "uniprot_canonical_ac": "P22138-1", "length": 1203, "uniprot_id": "RPA2_YEAST", "protein_name": "DNA-directed RNA polymerase I subunit RPA135", "refseq_ac": "NP_015335", "refseq_name": "DNA-directed RNA polymerase I core subunit RPA135", "gene_name": "RPA135", "gene_names_uniprotkb": "RPA135; RPA2; RRN2; SRP3; YP9531.03C", "gene_names_refseq": "RPA135; RPA2; RRN2; SRP3", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22138", "url": "https://www.uniprot.org/uniprotkb/P22138" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-06-19", "authors": "Smolka Marcus B, Albuquerque Claudio P, Chen Sheng-hong, Zhou Huilin", "evidence": [ { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" } ], "reference": [ { "type": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000006214", "url": "https://www.yeastgenome.org/locus/S000006214", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IGEKVIFDGKPLNSEDEISN", "down_seq": "GYLGNKLSVSVEQVSIAKPM", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22138", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22138" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "SGD", "id": "S000006214", "url": "https://www.yeastgenome.org/locus/S000006214" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser88" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "677", "end_pos": "677" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1104", "end_pos": "1104" }, { "start_pos": "1107", "end_pos": "1107" }, { "start_pos": "1127", "end_pos": "1127" }, { "start_pos": "1128", "end_pos": "1128" }, { "start_pos": "1131", "end_pos": "1131" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1049", "end_pos": "1049" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "1122", "end_pos": "1122" }, { "start_pos": "1124", "end_pos": "1124" }, { "start_pos": "1145", "end_pos": "1145" }, { "start_pos": "1156", "end_pos": "1156" }, { "start_pos": "115", "end_pos": "115" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "737", "end_pos": "737" }, { "start_pos": "746", "end_pos": "746" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "86", "end_pos": "86" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P22138-1.81.81", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P22138-1.86.86", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22139-1.20.20", "start_pos": 20, "end_pos": 20, "uniprot_canonical_ac": "P22139-1", "length": 70, "uniprot_id": "RPAB5_YEAST", "protein_name": "DNA-directed RNA polymerases I, II, and III subunit RPABC5", "refseq_ac": "NP_014853", "refseq_name": "DNA-directed RNA polymerase core subunit RPB10", "gene_name": "RPB10", "gene_names_uniprotkb": "RPB10", "gene_names_refseq": "RPB10", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22139", "url": "https://www.uniprot.org/uniprotkb/P22139" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22139", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22139" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005736", "url": "https://www.yeastgenome.org/locus/S000005736", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22139", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22139", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "", "down_seq": "YLNLLQEDELDEGTALSRLG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005736", "url": "https://www.yeastgenome.org/locus/S000005736" }, { "database": "iPTMnet", "id": "P22139", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22139" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser20" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "20", "end_pos": "20" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22146-1.149.149", "start_pos": 149, "end_pos": 149, "uniprot_canonical_ac": "P22146-1", "length": 559, "uniprot_id": "GAS1_YEAST", "protein_name": "1,3-beta-glucanosyltransferase GAS1", "refseq_ac": "NP_014038", "refseq_name": "1,3-beta-glucanosyltransferase GAS1", "gene_name": "GAS1", "gene_names_uniprotkb": "GAS1; GGP1; YM9952.09", "gene_names_refseq": "CWH52; GAS1; GGP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [], "crossref": [ { "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "DPTWTVDLFNSYKTVVDTFA", "down_seq": "YTNVLGFFAGNEVTNNYTNT", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn149", "evidence": [ { "id": "P22146", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22146#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "149", "end_pos": "149" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "495", "end_pos": "495" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "262", "end_pos": "262" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "348", "end_pos": "348" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "211", "end_pos": "211" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "419", "end_pos": "419" }, { "start_pos": "422", "end_pos": "422" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "upstream", "id": "P22146-1.161.161", "categories": [ "mutagenesis_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P22146-1.165.165", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P22146-1.165.165", "start_pos": 165, "end_pos": 165, "uniprot_canonical_ac": "P22146-1", "length": 559, "uniprot_id": "GAS1_YEAST", "protein_name": "1,3-beta-glucanosyltransferase GAS1", "refseq_ac": "NP_014038", "refseq_name": "1,3-beta-glucanosyltransferase GAS1", "gene_name": "GAS1", "gene_names_uniprotkb": "GAS1; GGP1; YM9952.09", "gene_names_refseq": "CWH52; GAS1; GGP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [], "crossref": [ { "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "DTFANYTNVLGFFAGNEVTN", "down_seq": "YTNTDASAFVKAAIRDVRQY", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn165", "evidence": [ { "id": "P22146", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22146#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "149", "end_pos": "149" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "495", "end_pos": "495" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "262", "end_pos": "262" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "348", "end_pos": "348" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "211", "end_pos": "211" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "419", "end_pos": "419" }, { "start_pos": "422", "end_pos": "422" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P22146-1.149.149", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P22146-1.161.161", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P22146-1.253.253", "start_pos": 253, "end_pos": 253, "uniprot_canonical_ac": "P22146-1", "length": 559, "uniprot_id": "GAS1_YEAST", "protein_name": "1,3-beta-glucanosyltransferase GAS1", "refseq_ac": "NP_014038", "refseq_name": "1,3-beta-glucanosyltransferase GAS1", "gene_name": "GAS1", "gene_names_uniprotkb": "GAS1; GGP1; YM9952.09", "gene_names_refseq": "CWH52; GAS1; GGP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [], "crossref": [ { "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "WCGKSDFKTSGYADRTAEFK", "down_seq": "LSIPVFFSEYGCNEVTPRLF", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn253", "evidence": [ { "id": "P22146", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22146#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "149", "end_pos": "149" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "495", "end_pos": "495" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "262", "end_pos": "262" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "348", "end_pos": "348" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "211", "end_pos": "211" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "419", "end_pos": "419" }, { "start_pos": "422", "end_pos": "422" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "upstream", "id": "P22146-1.262.262", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P22146-1.265.265", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P22146-1.283.283", "start_pos": 283, "end_pos": 283, "uniprot_canonical_ac": "P22146-1", "length": 559, "uniprot_id": "GAS1_YEAST", "protein_name": "1,3-beta-glucanosyltransferase GAS1", "refseq_ac": "NP_014038", "refseq_name": "1,3-beta-glucanosyltransferase GAS1", "gene_name": "GAS1", "gene_names_uniprotkb": "GAS1; GGP1; YM9952.09", "gene_names_refseq": "CWH52; GAS1; GGP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [], "crossref": [ { "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "YGCNEVTPRLFTEVEALYGS", "down_seq": "MTDVWSGGIVYMYFEETNKY", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn283", "evidence": [ { "id": "P22146", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22146#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "149", "end_pos": "149" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "495", "end_pos": "495" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "262", "end_pos": "262" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "348", "end_pos": "348" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "211", "end_pos": "211" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "419", "end_pos": "419" }, { "start_pos": "422", "end_pos": "422" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P22146-1.265.265", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P22146-1.321.321", "start_pos": 321, "end_pos": 321, "uniprot_canonical_ac": "P22146-1", "length": 559, "uniprot_id": "GAS1_YEAST", "protein_name": "1,3-beta-glucanosyltransferase GAS1", "refseq_ac": "NP_014038", "refseq_name": "1,3-beta-glucanosyltransferase GAS1", "gene_name": "GAS1", "gene_names_uniprotkb": "GAS1; GGP1; YM9952.09", "gene_names_refseq": "CWH52; GAS1; GGP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [], "crossref": [ { "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "NKYGLVSIDGNDVKTLDDFN", "down_seq": "YSSEINKISPTSANTKSYSA", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn321", "evidence": [ { "id": "P22146", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22146#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "149", "end_pos": "149" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "495", "end_pos": "495" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "262", "end_pos": "262" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "348", "end_pos": "348" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "211", "end_pos": "211" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "419", "end_pos": "419" }, { "start_pos": "422", "end_pos": "422" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "upstream", "id": "P22146-1.332.332", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P22146-1.332.332", "start_pos": 332, "end_pos": 332, "uniprot_canonical_ac": "P22146-1", "length": 559, "uniprot_id": "GAS1_YEAST", "protein_name": "1,3-beta-glucanosyltransferase GAS1", "refseq_ac": "NP_014038", "refseq_name": "1,3-beta-glucanosyltransferase GAS1", "gene_name": "GAS1", "gene_names_uniprotkb": "GAS1; GGP1; YM9952.09", "gene_names_refseq": "CWH52; GAS1; GGP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [], "crossref": [ { "id": "GLY_001160", "url": "https://data.glygen.org/GLY_001160", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "DVKTLDDFNNYSSEINKISP", "down_seq": "SANTKSYSATTSDVACPATG", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr332", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "149", "end_pos": "149" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "495", "end_pos": "495" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "262", "end_pos": "262" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "348", "end_pos": "348" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "211", "end_pos": "211" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "419", "end_pos": "419" }, { "start_pos": "422", "end_pos": "422" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P22146-1.321.321", "categories": [ "glycosylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P22146-1.348.348", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P22146-1.409.409", "start_pos": 409, "end_pos": 409, "uniprot_canonical_ac": "P22146-1", "length": 559, "uniprot_id": "GAS1_YEAST", "protein_name": "1,3-beta-glucanosyltransferase GAS1", "refseq_ac": "NP_014038", "refseq_name": "1,3-beta-glucanosyltransferase GAS1", "gene_name": "GAS1", "gene_names_uniprotkb": "GAS1; GGP1; YM9952.09", "gene_names_refseq": "CWH52; GAS1; GGP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [], "crossref": [ { "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "DYETLFNWICNEVDCSGISA", "down_seq": "GTAGKYGAYSFCTPKEQLSF", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn409", "evidence": [ { "id": "P22146", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22146#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "149", "end_pos": "149" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "495", "end_pos": "495" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "262", "end_pos": "262" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "348", "end_pos": "348" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "211", "end_pos": "211" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "419", "end_pos": "419" }, { "start_pos": "422", "end_pos": "422" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "upstream", "id": "P22146-1.415.415", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P22146-1.419.419", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P22146-1.422.422", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P22146-1.40.40", "start_pos": 40, "end_pos": 40, "uniprot_canonical_ac": "P22146-1", "length": 559, "uniprot_id": "GAS1_YEAST", "protein_name": "1,3-beta-glucanosyltransferase GAS1", "refseq_ac": "NP_014038", "refseq_name": "1,3-beta-glucanosyltransferase GAS1", "gene_name": "GAS1", "gene_names_uniprotkb": "GAS1; GGP1; YM9952.09", "gene_names_refseq": "CWH52; GAS1; GGP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [], "crossref": [ { "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "ATADDVPAIEVVGNKFFYSN", "down_seq": "GSQFYIRGVAYQADTANETS", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn40", "evidence": [ { "id": "P22146", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22146#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "149", "end_pos": "149" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "495", "end_pos": "495" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "262", "end_pos": "262" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "348", "end_pos": "348" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "211", "end_pos": "211" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "419", "end_pos": "419" }, { "start_pos": "422", "end_pos": "422" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "upstream", "id": "P22146-1.57.57", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P22146-1.495.495", "start_pos": 495, "end_pos": 495, "uniprot_canonical_ac": "P22146-1", "length": 559, "uniprot_id": "GAS1_YEAST", "protein_name": "1,3-beta-glucanosyltransferase GAS1", "refseq_ac": "NP_014038", "refseq_name": "1,3-beta-glucanosyltransferase GAS1", "gene_name": "GAS1", "gene_names_uniprotkb": "GAS1; GGP1; YM9952.09", "gene_names_refseq": "CWH52; GAS1; GGP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [], "crossref": [ { "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "NSASGSVDLGSGTESSTASS", "down_seq": "ASGSSSKSNSGSSGSSSSSS", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn495", "evidence": [ { "id": "P22146", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22146#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "149", "end_pos": "149" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "495", "end_pos": "495" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "262", "end_pos": "262" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "348", "end_pos": "348" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "211", "end_pos": "211" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "419", "end_pos": "419" }, { "start_pos": "422", "end_pos": "422" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P22146-1.57.57", "start_pos": 57, "end_pos": 57, "uniprot_canonical_ac": "P22146-1", "length": 559, "uniprot_id": "GAS1_YEAST", "protein_name": "1,3-beta-glucanosyltransferase GAS1", "refseq_ac": "NP_014038", "refseq_name": "1,3-beta-glucanosyltransferase GAS1", "gene_name": "GAS1", "gene_names_uniprotkb": "GAS1; GGP1; YM9952.09", "gene_names_refseq": "CWH52; GAS1; GGP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [], "crossref": [ { "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "YSNNGSQFYIRGVAYQADTA", "down_seq": "ETSGSTVNDPLANYESCSRD", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn57", "evidence": [ { "id": "P22146", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22146#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "149", "end_pos": "149" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "495", "end_pos": "495" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "262", "end_pos": "262" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "348", "end_pos": "348" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "211", "end_pos": "211" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "419", "end_pos": "419" }, { "start_pos": "422", "end_pos": "422" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P22146-1.40.40", "categories": [ "glycosylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P22146-1.74.74", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P22146-1.95.95", "start_pos": 95, "end_pos": 95, "uniprot_canonical_ac": "P22146-1", "length": 559, "uniprot_id": "GAS1_YEAST", "protein_name": "1,3-beta-glucanosyltransferase GAS1", "refseq_ac": "NP_014038", "refseq_name": "1,3-beta-glucanosyltransferase GAS1", "gene_name": "GAS1", "gene_names_uniprotkb": "GAS1; GGP1; YM9952.09", "gene_names_refseq": "CWH52; GAS1; GGP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [], "crossref": [ { "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "SRDIPYLKKLNTNVIRVYAI", "down_seq": "TTLDHSECMKALNDADIYVI", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn95", "evidence": [ { "id": "P22146", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22146#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "149", "end_pos": "149" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "495", "end_pos": "495" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "262", "end_pos": "262" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "348", "end_pos": "348" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "211", "end_pos": "211" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "419", "end_pos": "419" }, { "start_pos": "422", "end_pos": "422" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "upstream", "id": "P22146-1.103.103", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P22146-1.103.103", "start_pos": 103, "end_pos": 103, "uniprot_canonical_ac": "P22146-1", "length": 559, "uniprot_id": "GAS1_YEAST", "protein_name": "1,3-beta-glucanosyltransferase GAS1", "refseq_ac": "NP_014038", "refseq_name": "1,3-beta-glucanosyltransferase GAS1", "gene_name": "GAS1", "gene_names_uniprotkb": "GAS1; GGP1; YM9952.09", "gene_names_refseq": "CWH52; GAS1; GGP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Characterization of recombinant forms of the yeast Gas1 protein and identification of residues essential for glucanosyltransferase activity and folding.", "journal": "European journal of biochemistry", "date": "2004", "authors": "Carotti C, Ragni E, Palomares O, Fontaine T, Tedeschi G, Rodriguez R, Latge JP, Vai M, Popolo L", "evidence": [ { "database": "UniProtKB", "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146" } ], "reference": [ { "type": "PubMed", "id": "15355340", "url": "https://glygen.org/publication/PubMed/15355340" } ] } ], "crossref": [ { "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "15355340", "url": "https://glygen.org/publication/PubMed/15355340", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "KLNTNVIRVYAINTTLDHSE", "down_seq": "MKALNDADIYVIADLAAPAT", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Partially impairs the folding and stability of the protein.", "evidence": [ { "database": "UniProtKB", "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146" }, { "database": "PubMed", "id": "15355340", "url": "https://glygen.org/publication/PubMed/15355340" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "149", "end_pos": "149" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "495", "end_pos": "495" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "262", "end_pos": "262" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "348", "end_pos": "348" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "211", "end_pos": "211" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "419", "end_pos": "419" }, { "start_pos": "422", "end_pos": "422" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "P22146-1.95.95", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22146-1.161.161", "start_pos": 161, "end_pos": 161, "uniprot_canonical_ac": "P22146-1", "length": 559, "uniprot_id": "GAS1_YEAST", "protein_name": "1,3-beta-glucanosyltransferase GAS1", "refseq_ac": "NP_014038", "refseq_name": "1,3-beta-glucanosyltransferase GAS1", "gene_name": "GAS1", "gene_names_uniprotkb": "GAS1; GGP1; YM9952.09", "gene_names_refseq": "CWH52; GAS1; GGP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Characterization of recombinant forms of the yeast Gas1 protein and identification of residues essential for glucanosyltransferase activity and folding.", "journal": "European journal of biochemistry", "date": "2004", "authors": "Carotti C, Ragni E, Palomares O, Fontaine T, Tedeschi G, Rodriguez R, Latge JP, Vai M, Popolo L", "evidence": [ { "database": "UniProtKB", "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146" } ], "reference": [ { "type": "PubMed", "id": "15355340", "url": "https://glygen.org/publication/PubMed/15355340" } ] } ], "crossref": [ { "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "15355340", "url": "https://glygen.org/publication/PubMed/15355340", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "E", "start_aa": "E", "up_seq": "KTVVDTFANYTNVLGFFAGN", "down_seq": "VTNNYTNTDASAFVKAAIRD", "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "Q", "comment": "Loss of function.", "evidence": [ { "database": "UniProtKB", "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146" }, { "database": "PubMed", "id": "15355340", "url": "https://glygen.org/publication/PubMed/15355340" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "149", "end_pos": "149" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "495", "end_pos": "495" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "262", "end_pos": "262" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "348", "end_pos": "348" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "211", "end_pos": "211" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "419", "end_pos": "419" }, { "start_pos": "422", "end_pos": "422" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P22146-1.149.149", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P22146-1.165.165", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22146-1.262.262", "start_pos": 262, "end_pos": 262, "uniprot_canonical_ac": "P22146-1", "length": 559, "uniprot_id": "GAS1_YEAST", "protein_name": "1,3-beta-glucanosyltransferase GAS1", "refseq_ac": "NP_014038", "refseq_name": "1,3-beta-glucanosyltransferase GAS1", "gene_name": "GAS1", "gene_names_uniprotkb": "GAS1; GGP1; YM9952.09", "gene_names_refseq": "CWH52; GAS1; GGP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Characterization of recombinant forms of the yeast Gas1 protein and identification of residues essential for glucanosyltransferase activity and folding.", "journal": "European journal of biochemistry", "date": "2004", "authors": "Carotti C, Ragni E, Palomares O, Fontaine T, Tedeschi G, Rodriguez R, Latge JP, Vai M, Popolo L", "evidence": [ { "database": "UniProtKB", "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146" } ], "reference": [ { "type": "PubMed", "id": "15355340", "url": "https://glygen.org/publication/PubMed/15355340" } ] } ], "crossref": [ { "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "15355340", "url": "https://glygen.org/publication/PubMed/15355340", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "E", "start_aa": "E", "up_seq": "SGYADRTAEFKNLSIPVFFS", "down_seq": "YGCNEVTPRLFTEVEALYGS", "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "Q", "comment": "Loss of function.", "evidence": [ { "database": "UniProtKB", "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146" }, { "database": "PubMed", "id": "15355340", "url": "https://glygen.org/publication/PubMed/15355340" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "149", "end_pos": "149" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "495", "end_pos": "495" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "262", "end_pos": "262" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "348", "end_pos": "348" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "211", "end_pos": "211" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "419", "end_pos": "419" }, { "start_pos": "422", "end_pos": "422" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "P22146-1.253.253", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P22146-1.265.265", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22146-1.265.265", "start_pos": 265, "end_pos": 265, "uniprot_canonical_ac": "P22146-1", "length": 559, "uniprot_id": "GAS1_YEAST", "protein_name": "1,3-beta-glucanosyltransferase GAS1", "refseq_ac": "NP_014038", "refseq_name": "1,3-beta-glucanosyltransferase GAS1", "gene_name": "GAS1", "gene_names_uniprotkb": "GAS1; GGP1; YM9952.09", "gene_names_refseq": "CWH52; GAS1; GGP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Characterization of recombinant forms of the yeast Gas1 protein and identification of residues essential for glucanosyltransferase activity and folding.", "journal": "European journal of biochemistry", "date": "2004", "authors": "Carotti C, Ragni E, Palomares O, Fontaine T, Tedeschi G, Rodriguez R, Latge JP, Vai M, Popolo L", "evidence": [ { "database": "UniProtKB", "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146" } ], "reference": [ { "type": "PubMed", "id": "15355340", "url": "https://glygen.org/publication/PubMed/15355340" } ] } ], "crossref": [ { "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "15355340", "url": "https://glygen.org/publication/PubMed/15355340", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "ADRTAEFKNLSIPVFFSEYG", "down_seq": "NEVTPRLFTEVEALYGSNMT", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Partially impairs the folding and stability of the protein.", "evidence": [ { "database": "UniProtKB", "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146" }, { "database": "PubMed", "id": "15355340", "url": "https://glygen.org/publication/PubMed/15355340" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "149", "end_pos": "149" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "495", "end_pos": "495" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "262", "end_pos": "262" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "348", "end_pos": "348" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "211", "end_pos": "211" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "419", "end_pos": "419" }, { "start_pos": "422", "end_pos": "422" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P22146-1.253.253", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P22146-1.262.262", "categories": [ "mutagenesis_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P22146-1.283.283", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22146-1.348.348", "start_pos": 348, "end_pos": 348, "uniprot_canonical_ac": "P22146-1", "length": 559, "uniprot_id": "GAS1_YEAST", "protein_name": "1,3-beta-glucanosyltransferase GAS1", "refseq_ac": "NP_014038", "refseq_name": "1,3-beta-glucanosyltransferase GAS1", "gene_name": "GAS1", "gene_names_uniprotkb": "GAS1; GGP1; YM9952.09", "gene_names_refseq": "CWH52; GAS1; GGP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Disulfide bond structure and domain organization of yeast beta(1,3)-glucanosyltransferases involved in cell wall biogenesis.", "journal": "The Journal of biological chemistry", "date": "2008-07-04", "authors": "Popolo Laura, Ragni Enrico, Carotti Cristina, Palomares Oscar, Aardema Ronald, Back Jaap Willem, Dekker Henk L, de Koning Leo J, de Jong Luitzen, de Koster Chris G", "evidence": [ { "database": "UniProtKB", "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146" } ], "reference": [ { "type": "PubMed", "id": "18468997", "url": "https://glygen.org/publication/PubMed/18468997" } ] } ], "crossref": [ { "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18468997", "url": "https://glygen.org/publication/PubMed/18468997", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "KISPTSANTKSYSATTSDVA", "down_seq": "PATGKYWSAATELPPTPNGG", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Impairs the folding and stability of the protein.", "evidence": [ { "database": "UniProtKB", "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146" }, { "database": "PubMed", "id": "18468997", "url": "https://glygen.org/publication/PubMed/18468997" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "149", "end_pos": "149" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "495", "end_pos": "495" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "262", "end_pos": "262" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "348", "end_pos": "348" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "211", "end_pos": "211" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "419", "end_pos": "419" }, { "start_pos": "422", "end_pos": "422" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P22146-1.332.332", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22146-1.74.74", "start_pos": 74, "end_pos": 74, "uniprot_canonical_ac": "P22146-1", "length": 559, "uniprot_id": "GAS1_YEAST", "protein_name": "1,3-beta-glucanosyltransferase GAS1", "refseq_ac": "NP_014038", "refseq_name": "1,3-beta-glucanosyltransferase GAS1", "gene_name": "GAS1", "gene_names_uniprotkb": "GAS1; GGP1; YM9952.09", "gene_names_refseq": "CWH52; GAS1; GGP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Characterization of recombinant forms of the yeast Gas1 protein and identification of residues essential for glucanosyltransferase activity and folding.", "journal": "European journal of biochemistry", "date": "2004", "authors": "Carotti C, Ragni E, Palomares O, Fontaine T, Tedeschi G, Rodriguez R, Latge JP, Vai M, Popolo L", "evidence": [ { "database": "UniProtKB", "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146" } ], "reference": [ { "type": "PubMed", "id": "15355340", "url": "https://glygen.org/publication/PubMed/15355340" } ] } ], "crossref": [ { "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "15355340", "url": "https://glygen.org/publication/PubMed/15355340", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "DTANETSGSTVNDPLANYES", "down_seq": "SRDIPYLKKLNTNVIRVYAI", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Impairs the folding and stability of the protein.", "evidence": [ { "database": "UniProtKB", "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146" }, { "database": "PubMed", "id": "15355340", "url": "https://glygen.org/publication/PubMed/15355340" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "149", "end_pos": "149" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "495", "end_pos": "495" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "262", "end_pos": "262" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "348", "end_pos": "348" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "211", "end_pos": "211" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "419", "end_pos": "419" }, { "start_pos": "422", "end_pos": "422" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P22146-1.57.57", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22146-1.211.211", "start_pos": 211, "end_pos": 211, "uniprot_canonical_ac": "P22146-1", "length": 559, "uniprot_id": "GAS1_YEAST", "protein_name": "1,3-beta-glucanosyltransferase GAS1", "refseq_ac": "NP_014038", "refseq_name": "1,3-beta-glucanosyltransferase GAS1", "gene_name": "GAS1", "gene_names_uniprotkb": "GAS1; GGP1; YM9952.09", "gene_names_refseq": "CWH52; GAS1; GGP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P22146", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22146" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "crossref": [ { "id": "S000004924", "url": "https://www.yeastgenome.org/locus/S000004924", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22146", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22146", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "YRKIPVGYSSNDDEDTRVKM", "down_seq": "DYFACGDDDVKADFYGINMY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004924", "url": "https://www.yeastgenome.org/locus/S000004924" }, { "database": "iPTMnet", "id": "P22146", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22146" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Thr211" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "149", "end_pos": "149" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "495", "end_pos": "495" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "262", "end_pos": "262" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "348", "end_pos": "348" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "211", "end_pos": "211" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "419", "end_pos": "419" }, { "start_pos": "422", "end_pos": "422" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22146-1.415.415", "start_pos": 415, "end_pos": 415, "uniprot_canonical_ac": "P22146-1", "length": 559, "uniprot_id": "GAS1_YEAST", "protein_name": "1,3-beta-glucanosyltransferase GAS1", "refseq_ac": "NP_014038", "refseq_name": "1,3-beta-glucanosyltransferase GAS1", "gene_name": "GAS1", "gene_names_uniprotkb": "GAS1; GGP1; YM9952.09", "gene_names_refseq": "CWH52; GAS1; GGP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "GPI-Modified Proteins Non-covalently Attached to Saccharomyces cerevisiae Yeast Cell Wall.", "journal": "Biochemistry. Biokhimiia", "date": "2019-12", "authors": "Rekstina V V, Bykova A A, Ziganshin R H, Kalebina T S", "evidence": [ { "database": "iPTMnet", "id": "P22146", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22146" } ], "reference": [ { "type": "PubMed", "id": "31870255", "url": "https://glygen.org/publication/PubMed/31870255" } ] } ], "crossref": [ { "id": "S000004924", "url": "https://www.yeastgenome.org/locus/S000004924", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22146", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22146", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "31870255", "url": "https://glygen.org/publication/PubMed/31870255", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "NWICNEVDCSGISANGTAGK", "down_seq": "GAYSFCTPKEQLSFVMNLYY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004924", "url": "https://www.yeastgenome.org/locus/S000004924" }, { "database": "iPTMnet", "id": "P22146", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22146" }, { "database": "PubMed", "id": "31870255", "url": "https://glygen.org/publication/PubMed/31870255" } ], "site_lbl": "Tyr415" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "149", "end_pos": "149" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "495", "end_pos": "495" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "262", "end_pos": "262" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "348", "end_pos": "348" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "211", "end_pos": "211" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "419", "end_pos": "419" }, { "start_pos": "422", "end_pos": "422" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "P22146-1.409.409", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P22146-1.419.419", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P22146-1.422.422", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22146-1.419.419", "start_pos": 419, "end_pos": 419, "uniprot_canonical_ac": "P22146-1", "length": 559, "uniprot_id": "GAS1_YEAST", "protein_name": "1,3-beta-glucanosyltransferase GAS1", "refseq_ac": "NP_014038", "refseq_name": "1,3-beta-glucanosyltransferase GAS1", "gene_name": "GAS1", "gene_names_uniprotkb": "GAS1; GGP1; YM9952.09", "gene_names_refseq": "CWH52; GAS1; GGP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22146", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22146" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000004924", "url": "https://www.yeastgenome.org/locus/S000004924", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22146", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22146", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NEVDCSGISANGTAGKYGAY", "down_seq": "FCTPKEQLSFVMNLYYEKSG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004924", "url": "https://www.yeastgenome.org/locus/S000004924" }, { "database": "iPTMnet", "id": "P22146", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22146" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser419" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "149", "end_pos": "149" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "495", "end_pos": "495" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "262", "end_pos": "262" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "348", "end_pos": "348" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "211", "end_pos": "211" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "419", "end_pos": "419" }, { "start_pos": "422", "end_pos": "422" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "P22146-1.409.409", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P22146-1.415.415", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P22146-1.422.422", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22146-1.422.422", "start_pos": 422, "end_pos": 422, "uniprot_canonical_ac": "P22146-1", "length": 559, "uniprot_id": "GAS1_YEAST", "protein_name": "1,3-beta-glucanosyltransferase GAS1", "refseq_ac": "NP_014038", "refseq_name": "1,3-beta-glucanosyltransferase GAS1", "gene_name": "GAS1", "gene_names_uniprotkb": "GAS1; GGP1; YM9952.09", "gene_names_refseq": "CWH52; GAS1; GGP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22146", "url": "https://www.uniprot.org/uniprotkb/P22146" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22146", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22146" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000004924", "url": "https://www.yeastgenome.org/locus/S000004924", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22146", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22146", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "DCSGISANGTAGKYGAYSFC", "down_seq": "PKEQLSFVMNLYYEKSGGSK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004924", "url": "https://www.yeastgenome.org/locus/S000004924" }, { "database": "iPTMnet", "id": "P22146", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22146" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr422" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "149", "end_pos": "149" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "495", "end_pos": "495" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "262", "end_pos": "262" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "348", "end_pos": "348" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "211", "end_pos": "211" }, { "start_pos": "415", "end_pos": "415" }, { "start_pos": "419", "end_pos": "419" }, { "start_pos": "422", "end_pos": "422" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P22146-1.409.409", "categories": [ "glycosylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P22146-1.415.415", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P22146-1.419.419", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.353.353", "start_pos": 353, "end_pos": 353, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P22211", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P22211" }, { "database": "O-GlcNAc Atlas", "id": "P22211", "url": "https://oglcnac.org/atlas/detail/P22211" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] }, { "title": "Identification of the rapamycin-sensitive phosphorylation sites within the Ser/Thr-rich domain of the yeast Npr1 protein kinase.", "journal": "Rapid communications in mass spectrometry : RCM", "date": "2008-12", "authors": "Gander Stefan, Bonenfant Debora, Altermatt Patrick, Martin Dietmar E, Hauri Simon, Moes Suzette, Hall Michael N, Jenoe Paul", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" } ] }, { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "Journal of proteome research", "date": "2007-03", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast.", "journal": "Science signaling", "date": "2010-12-21", "authors": "Bodenmiller Bernd, Wanka Stefanie, Kraft Claudine, Urban J\u00f6rg, Campbell David, Pedrioli Patrick G, Gerrits Bertran, Picotti Paola, Lam Henry, Vitek Olga, Brusniak Mi-Youn, Roschitzki Bernd, Zhang Chao, Shokat Kevan M, Schlapbach Ralph, Colman-Lerner Alejandro, Nolan Garry P, Nesvizhskii Alexey I, Peter Matthias, Loewith Robbie, von Mering Christian, Aebersold Ruedi", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22211", "url": "https://oglcnac.org/atlas/detail/P22211", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FYGSPSSVHDHLPPSQSVPR", "down_seq": "QHSSIGDLKRFFKKSSNSNL", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser353", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P22211", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P22211" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser353" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P22211-1.334.334", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P22211-1.336.336", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P22211-1.338.338", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P22211-1.339.339", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P22211-1.347.347", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P22211-1.349.349", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P22211-1.356.356", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P22211-1.357.357", "categories": [ "glycosylation_flag", "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P22211-1.369.369", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.356.356", "start_pos": 356, "end_pos": 356, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P22211", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P22211" }, { "database": "O-GlcNAc Atlas", "id": "P22211", "url": "https://oglcnac.org/atlas/detail/P22211" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] }, { "title": "Identification of the rapamycin-sensitive phosphorylation sites within the Ser/Thr-rich domain of the yeast Npr1 protein kinase.", "journal": "Rapid communications in mass spectrometry : RCM", "date": "2008-12", "authors": "Gander Stefan, Bonenfant Debora, Altermatt Patrick, Martin Dietmar E, Hauri Simon, Moes Suzette, Hall Michael N, Jenoe Paul", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Mol. Cell. Proteomics", "date": "2008", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22211", "url": "https://oglcnac.org/atlas/detail/P22211", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SPSSVHDHLPPSQSVPRSQH", "down_seq": "SIGDLKRFFKKSSNSNLSSN", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser356", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P22211", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P22211" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser356" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P22211-1.336.336", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "downstream", "id": "P22211-1.338.338", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P22211-1.339.339", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P22211-1.347.347", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P22211-1.349.349", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P22211-1.353.353", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P22211-1.357.357", "categories": [ "glycosylation_flag", "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P22211-1.369.369", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.357.357", "start_pos": 357, "end_pos": 357, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P22211", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P22211" }, { "database": "O-GlcNAc Atlas", "id": "P22211", "url": "https://oglcnac.org/atlas/detail/P22211" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] }, { "title": "Identification of the rapamycin-sensitive phosphorylation sites within the Ser/Thr-rich domain of the yeast Npr1 protein kinase.", "journal": "Rapid communications in mass spectrometry : RCM", "date": "2008-12", "authors": "Gander Stefan, Bonenfant Debora, Altermatt Patrick, Martin Dietmar E, Hauri Simon, Moes Suzette, Hall Michael N, Jenoe Paul", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" } ] }, { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "Journal of proteome research", "date": "2007-03", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Mol. Cell. Proteomics", "date": "2008", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast.", "journal": "Science signaling", "date": "2010-12-21", "authors": "Bodenmiller Bernd, Wanka Stefanie, Kraft Claudine, Urban J\u00f6rg, Campbell David, Pedrioli Patrick G, Gerrits Bertran, Picotti Paola, Lam Henry, Vitek Olga, Brusniak Mi-Youn, Roschitzki Bernd, Zhang Chao, Shokat Kevan M, Schlapbach Ralph, Colman-Lerner Alejandro, Nolan Garry P, Nesvizhskii Alexey I, Peter Matthias, Loewith Robbie, von Mering Christian, Aebersold Ruedi", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22211", "url": "https://oglcnac.org/atlas/detail/P22211", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PSSVHDHLPPSQSVPRSQHS", "down_seq": "IGDLKRFFKKSSNSNLSSNS", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser357", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P22211", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P22211" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Abolishes autophosphorylation; when associated with A-47 and A-257.", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P22211-1", "kinase_gene_name": "NPR1", "residue": "Ser", "comment": "", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ], "site_lbl": "Ser357" }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by autocatalysis", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser357" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "glycosylation_flag", "mutagenesis_flag", "phosphorylation_flag" ], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P22211-1.338.338", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "downstream", "id": "P22211-1.339.339", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P22211-1.347.347", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P22211-1.349.349", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P22211-1.353.353", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P22211-1.356.356", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P22211-1.369.369", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 12 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.45.45", "start_pos": 45, "end_pos": 45, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P22211", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P22211" }, { "database": "O-GlcNAc Atlas", "id": "P22211", "url": "https://oglcnac.org/atlas/detail/P22211" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Mol. Cell. Proteomics", "date": "2008", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22211", "url": "https://oglcnac.org/atlas/detail/P22211", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ADTLTTTPESQSLDLHSRNK", "down_seq": "SSHIGSVSNSSSSDRNRANV", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser45", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P22211", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P22211" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser45" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P22211-1.27.27", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P22211-1.31.31", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P22211-1.46.46", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P22211-1.47.47", "categories": [ "glycosylation_flag", "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P22211-1.51.51", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P22211-1.53.53", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P22211-1.55.55", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P22211-1.56.56", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P22211-1.57.57", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P22211-1.58.58", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 7 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.46.46", "start_pos": 46, "end_pos": 46, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P22211", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P22211" }, { "database": "O-GlcNAc Atlas", "id": "P22211", "url": "https://oglcnac.org/atlas/detail/P22211" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] }, { "title": "Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast.", "journal": "Science signaling", "date": "2010-12-21", "authors": "Bodenmiller Bernd, Wanka Stefanie, Kraft Claudine, Urban J\u00f6rg, Campbell David, Pedrioli Patrick G, Gerrits Bertran, Picotti Paola, Lam Henry, Vitek Olga, Brusniak Mi-Youn, Roschitzki Bernd, Zhang Chao, Shokat Kevan M, Schlapbach Ralph, Colman-Lerner Alejandro, Nolan Garry P, Nesvizhskii Alexey I, Peter Matthias, Loewith Robbie, von Mering Christian, Aebersold Ruedi", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22211", "url": "https://oglcnac.org/atlas/detail/P22211", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DTLTTTPESQSLDLHSRNKS", "down_seq": "SHIGSVSNSSSSDRNRANVP", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser46", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P22211", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P22211" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ], "site_lbl": "Ser46" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P22211-1.27.27", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P22211-1.31.31", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P22211-1.45.45", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P22211-1.47.47", "categories": [ "glycosylation_flag", "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P22211-1.51.51", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P22211-1.53.53", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P22211-1.55.55", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P22211-1.56.56", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P22211-1.57.57", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P22211-1.58.58", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.47.47", "start_pos": 47, "end_pos": 47, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P22211", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P22211" }, { "database": "O-GlcNAc Atlas", "id": "P22211", "url": "https://oglcnac.org/atlas/detail/P22211" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] }, { "title": "Identification of the rapamycin-sensitive phosphorylation sites within the Ser/Thr-rich domain of the yeast Npr1 protein kinase.", "journal": "Rapid communications in mass spectrometry : RCM", "date": "2008-12", "authors": "Gander Stefan, Bonenfant Debora, Altermatt Patrick, Martin Dietmar E, Hauri Simon, Moes Suzette, Hall Michael N, Jenoe Paul", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22211", "url": "https://oglcnac.org/atlas/detail/P22211", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TLTTTPESQSLDLHSRNKSS", "down_seq": "HIGSVSNSSSSDRNRANVPV", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser47", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P22211", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P22211" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Abolishes autophosphorylation; when associated with A-257 and A-357.", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P22211-1", "kinase_gene_name": "NPR1", "residue": "Ser", "comment": "", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" } ], "site_lbl": "Ser47" }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by autocatalysis", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser47" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "glycosylation_flag", "mutagenesis_flag", "phosphorylation_flag" ], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P22211-1.27.27", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P22211-1.31.31", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P22211-1.45.45", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P22211-1.46.46", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P22211-1.51.51", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P22211-1.53.53", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P22211-1.55.55", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P22211-1.56.56", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P22211-1.57.57", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P22211-1.58.58", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.51.51", "start_pos": 51, "end_pos": 51, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P22211", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P22211" }, { "database": "O-GlcNAc Atlas", "id": "P22211", "url": "https://oglcnac.org/atlas/detail/P22211" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22211", "url": "https://oglcnac.org/atlas/detail/P22211", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TPESQSLDLHSRNKSSSHIG", "down_seq": "VSNSSSSDRNRANVPVPGSV", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser51", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P22211", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P22211" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser51" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P22211-1.31.31", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P22211-1.45.45", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P22211-1.46.46", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P22211-1.47.47", "categories": [ "glycosylation_flag", "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P22211-1.53.53", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P22211-1.55.55", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P22211-1.56.56", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P22211-1.57.57", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P22211-1.58.58", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.53.53", "start_pos": 53, "end_pos": 53, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P22211", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P22211" }, { "database": "O-GlcNAc Atlas", "id": "P22211", "url": "https://oglcnac.org/atlas/detail/P22211" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22211", "url": "https://oglcnac.org/atlas/detail/P22211", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ESQSLDLHSRNKSSSHIGSV", "down_seq": "NSSSSDRNRANVPVPGSVTT", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser53", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P22211", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P22211" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser53" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "P22211-1.45.45", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P22211-1.46.46", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P22211-1.47.47", "categories": [ "glycosylation_flag", "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P22211-1.51.51", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P22211-1.55.55", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P22211-1.56.56", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P22211-1.57.57", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P22211-1.58.58", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.55.55", "start_pos": 55, "end_pos": 55, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P22211", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P22211" }, { "database": "O-GlcNAc Atlas", "id": "P22211", "url": "https://oglcnac.org/atlas/detail/P22211" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22211", "url": "https://oglcnac.org/atlas/detail/P22211", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QSLDLHSRNKSSSHIGSVSN", "down_seq": "SSSDRNRANVPVPGSVTTVT", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser55", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P22211", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P22211" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser55" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "P22211-1.45.45", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P22211-1.46.46", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P22211-1.47.47", "categories": [ "glycosylation_flag", "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P22211-1.51.51", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P22211-1.53.53", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P22211-1.56.56", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P22211-1.57.57", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P22211-1.58.58", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.56.56", "start_pos": 56, "end_pos": 56, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P22211", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P22211" }, { "database": "O-GlcNAc Atlas", "id": "P22211", "url": "https://oglcnac.org/atlas/detail/P22211" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22211", "url": "https://oglcnac.org/atlas/detail/P22211", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SLDLHSRNKSSSHIGSVSNS", "down_seq": "SSDRNRANVPVPGSVTTVTQ", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser56", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P22211", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P22211" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser56" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P22211-1.45.45", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P22211-1.46.46", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P22211-1.47.47", "categories": [ "glycosylation_flag", "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P22211-1.51.51", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P22211-1.53.53", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P22211-1.55.55", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P22211-1.57.57", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P22211-1.58.58", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.57.57", "start_pos": 57, "end_pos": 57, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P22211", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P22211" }, { "database": "O-GlcNAc Atlas", "id": "P22211", "url": "https://oglcnac.org/atlas/detail/P22211" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22211", "url": "https://oglcnac.org/atlas/detail/P22211", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LDLHSRNKSSSHIGSVSNSS", "down_seq": "SDRNRANVPVPGSVTTVTQI", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser57", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P22211", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P22211" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser57" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P22211-1.45.45", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P22211-1.46.46", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P22211-1.47.47", "categories": [ "glycosylation_flag", "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P22211-1.51.51", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P22211-1.53.53", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P22211-1.55.55", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P22211-1.56.56", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P22211-1.58.58", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.58.58", "start_pos": 58, "end_pos": 58, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P22211", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P22211" }, { "database": "O-GlcNAc Atlas", "id": "P22211", "url": "https://oglcnac.org/atlas/detail/P22211" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22211", "url": "https://oglcnac.org/atlas/detail/P22211", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DLHSRNKSSSHIGSVSNSSS", "down_seq": "DRNRANVPVPGSVTTVTQIY", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser58", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P22211", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P22211" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P22211-1.45.45", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P22211-1.46.46", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P22211-1.47.47", "categories": [ "glycosylation_flag", "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P22211-1.51.51", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P22211-1.53.53", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P22211-1.55.55", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P22211-1.56.56", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P22211-1.57.57", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P22211", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P22211" }, { "database": "O-GlcNAc Atlas", "id": "P22211", "url": "https://oglcnac.org/atlas/detail/P22211" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22211", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P22211", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P22211", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P22211" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "upstream", "id": "P22211-1.20.20", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.257.257", "start_pos": 257, "end_pos": 257, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of the rapamycin-sensitive phosphorylation sites within the Ser/Thr-rich domain of the yeast Npr1 protein kinase.", "journal": "Rapid communications in mass spectrometry : RCM", "date": "2008-12", "authors": "Gander Stefan, Bonenfant Debora, Altermatt Patrick, Martin Dietmar E, Hauri Simon, Moes Suzette, Hall Michael N, Jenoe Paul", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" } ] }, { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "Journal of proteome research", "date": "2007-03", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ASMDSNNANATQSRSISRSG", "down_seq": "FSSQLGNFFFSKNSKESSNS", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Abolishes autophosphorylation; when associated with A-47 and A-357.", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" } ] }, { "sequence_org": "S", "sequence_mut": "D", "comment": "Abolishes autophosphorylation.", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P22211-1", "kinase_gene_name": "NPR1", "residue": "Ser", "comment": "", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" } ], "site_lbl": "Ser257" }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by autocatalysis", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser257" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "mutagenesis_flag", "phosphorylation_flag" ], "glycosylation": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P22211-1.238.238", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P22211-1.241.241", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P22211-1.247.247", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P22211-1.249.249", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P22211-1.251.251", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P22211-1.253.253", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P22211-1.255.255", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P22211-1.259.259", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P22211-1.260.260", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.100.100", "start_pos": 100, "end_pos": 100, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of the rapamycin-sensitive phosphorylation sites within the Ser/Thr-rich domain of the yeast Npr1 protein kinase.", "journal": "Rapid communications in mass spectrometry : RCM", "date": "2008-12", "authors": "Gander Stefan, Bonenfant Debora, Altermatt Patrick, Martin Dietmar E, Hauri Simon, Moes Suzette, Hall Michael N, Jenoe Paul", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Mol. Cell. Proteomics", "date": "2008", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ], "crossref": [ { "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EEDSSSTAGSSLDDRNQFSS", "down_seq": "FLNANFAHTASFYGTSAQSR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" } ], "site_lbl": "Ser100" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P22211-1.85.85", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P22211-1.89.89", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P22211-1.90.90", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P22211-1.111.111", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P22211-1.113.113", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P22211-1.116.116", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P22211-1.119.119", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.111.111", "start_pos": 111, "end_pos": 111, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of the rapamycin-sensitive phosphorylation sites within the Ser/Thr-rich domain of the yeast Npr1 protein kinase.", "journal": "Rapid communications in mass spectrometry : RCM", "date": "2008-12", "authors": "Gander Stefan, Bonenfant Debora, Altermatt Patrick, Martin Dietmar E, Hauri Simon, Moes Suzette, Hall Michael N, Jenoe Paul", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" } ] } ], "crossref": [ { "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LDDRNQFSSSFLNANFAHTA", "down_seq": "FYGTSAQSRDRFGSLINDQG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" } ], "site_lbl": "Ser111" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P22211-1.100.100", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P22211-1.113.113", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P22211-1.116.116", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P22211-1.119.119", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P22211-1.125.125", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.113.113", "start_pos": 113, "end_pos": 113, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] } ], "crossref": [ { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "DRNQFSSSFLNANFAHTASF", "down_seq": "GTSAQSRDRFGSLINDQGTA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" } ], "site_lbl": "Tyr113" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P22211-1.100.100", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P22211-1.111.111", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P22211-1.116.116", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P22211-1.119.119", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P22211-1.125.125", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P22211-1.132.132", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.116.116", "start_pos": 116, "end_pos": 116, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of the rapamycin-sensitive phosphorylation sites within the Ser/Thr-rich domain of the yeast Npr1 protein kinase.", "journal": "Rapid communications in mass spectrometry : RCM", "date": "2008-12", "authors": "Gander Stefan, Bonenfant Debora, Altermatt Patrick, Martin Dietmar E, Hauri Simon, Moes Suzette, Hall Michael N, Jenoe Paul", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Mol. Cell. Proteomics", "date": "2008", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QFSSSFLNANFAHTASFYGT", "down_seq": "AQSRDRFGSLINDQGTAGLS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser116" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P22211-1.100.100", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P22211-1.111.111", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P22211-1.113.113", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P22211-1.119.119", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P22211-1.125.125", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P22211-1.132.132", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P22211-1.136.136", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.119.119", "start_pos": 119, "end_pos": 119, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SSFLNANFAHTASFYGTSAQ", "down_seq": "RDRFGSLINDQGTAGLSSHG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser119" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P22211-1.100.100", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P22211-1.111.111", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P22211-1.113.113", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P22211-1.116.116", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P22211-1.125.125", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P22211-1.132.132", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P22211-1.136.136", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P22211-1.137.137", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.125.125", "start_pos": 125, "end_pos": 125, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "Journal of proteome research", "date": "2007-03", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "Identification of the rapamycin-sensitive phosphorylation sites within the Ser/Thr-rich domain of the yeast Npr1 protein kinase.", "journal": "Rapid communications in mass spectrometry : RCM", "date": "2008-12", "authors": "Gander Stefan, Bonenfant Debora, Altermatt Patrick, Martin Dietmar E, Hauri Simon, Moes Suzette, Hall Michael N, Jenoe Paul", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NFAHTASFYGTSAQSRDRFG", "down_seq": "LINDQGTAGLSSHGGSFAAQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser125" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "P22211-1.111.111", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P22211-1.113.113", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P22211-1.116.116", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P22211-1.119.119", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P22211-1.132.132", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P22211-1.136.136", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P22211-1.137.137", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P22211-1.141.141", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.132.132", "start_pos": 132, "end_pos": 132, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "FYGTSAQSRDRFGSLINDQG", "down_seq": "AGLSSHGGSFAAQNRITSRL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr132" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P22211-1.113.113", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P22211-1.116.116", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P22211-1.119.119", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P22211-1.125.125", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P22211-1.136.136", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P22211-1.137.137", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P22211-1.141.141", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P22211-1.150.150", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.136.136", "start_pos": 136, "end_pos": 136, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SAQSRDRFGSLINDQGTAGL", "down_seq": "SHGGSFAAQNRITSRLSTTS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser136" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P22211-1.116.116", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P22211-1.119.119", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P22211-1.125.125", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P22211-1.132.132", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P22211-1.137.137", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P22211-1.141.141", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P22211-1.150.150", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P22211-1.153.153", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P22211-1.154.154", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P22211-1.156.156", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.137.137", "start_pos": 137, "end_pos": 137, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of the rapamycin-sensitive phosphorylation sites within the Ser/Thr-rich domain of the yeast Npr1 protein kinase.", "journal": "Rapid communications in mass spectrometry : RCM", "date": "2008-12", "authors": "Gander Stefan, Bonenfant Debora, Altermatt Patrick, Martin Dietmar E, Hauri Simon, Moes Suzette, Hall Michael N, Jenoe Paul", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AQSRDRFGSLINDQGTAGLS", "down_seq": "HGGSFAAQNRITSRLSTTSH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser137" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P22211-1.119.119", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P22211-1.125.125", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P22211-1.132.132", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P22211-1.136.136", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P22211-1.141.141", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P22211-1.150.150", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P22211-1.153.153", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P22211-1.154.154", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P22211-1.156.156", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.141.141", "start_pos": 141, "end_pos": 141, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Identification of the rapamycin-sensitive phosphorylation sites within the Ser/Thr-rich domain of the yeast Npr1 protein kinase.", "journal": "Rapid communications in mass spectrometry : RCM", "date": "2008-12", "authors": "Gander Stefan, Bonenfant Debora, Altermatt Patrick, Martin Dietmar E, Hauri Simon, Moes Suzette, Hall Michael N, Jenoe Paul", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DRFGSLINDQGTAGLSSHGG", "down_seq": "FAAQNRITSRLSTTSHTSGR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser141" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P22211-1.125.125", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P22211-1.132.132", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P22211-1.136.136", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P22211-1.137.137", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P22211-1.150.150", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P22211-1.153.153", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P22211-1.154.154", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P22211-1.156.156", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P22211-1.158.158", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P22211-1.159.159", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.150.150", "start_pos": 150, "end_pos": 150, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QGTAGLSSHGGSFAAQNRIT", "down_seq": "RLSTTSHTSGRAIPSLSSSI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser150" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P22211-1.132.132", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P22211-1.136.136", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P22211-1.137.137", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P22211-1.141.141", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P22211-1.153.153", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P22211-1.154.154", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P22211-1.156.156", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P22211-1.158.158", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P22211-1.159.159", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P22211-1.165.165", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P22211-1.167.167", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P22211-1.168.168", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P22211-1.169.169", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.153.153", "start_pos": 153, "end_pos": 153, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AGLSSHGGSFAAQNRITSRL", "down_seq": "TTSHTSGRAIPSLSSSIPYS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser153" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P22211-1.136.136", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P22211-1.137.137", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P22211-1.141.141", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P22211-1.150.150", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P22211-1.154.154", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P22211-1.156.156", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P22211-1.158.158", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P22211-1.159.159", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P22211-1.165.165", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P22211-1.167.167", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P22211-1.168.168", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P22211-1.169.169", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P22211-1.172.172", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P22211-1.173.173", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.154.154", "start_pos": 154, "end_pos": 154, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "crossref": [ { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "GLSSHGGSFAAQNRITSRLS", "down_seq": "TSHTSGRAIPSLSSSIPYSV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Thr154" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P22211-1.136.136", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P22211-1.137.137", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P22211-1.141.141", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P22211-1.150.150", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P22211-1.153.153", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P22211-1.156.156", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P22211-1.158.158", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P22211-1.159.159", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P22211-1.165.165", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P22211-1.167.167", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P22211-1.168.168", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P22211-1.169.169", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P22211-1.172.172", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P22211-1.173.173", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.156.156", "start_pos": 156, "end_pos": 156, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SSHGGSFAAQNRITSRLSTT", "down_seq": "HTSGRAIPSLSSSIPYSVPN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser156" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P22211-1.136.136", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "downstream", "id": "P22211-1.137.137", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P22211-1.141.141", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P22211-1.150.150", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P22211-1.153.153", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P22211-1.154.154", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P22211-1.158.158", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P22211-1.159.159", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P22211-1.165.165", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P22211-1.167.167", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P22211-1.168.168", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P22211-1.169.169", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P22211-1.172.172", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P22211-1.173.173", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.158.158", "start_pos": 158, "end_pos": 158, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "HGGSFAAQNRITSRLSTTSH", "down_seq": "SGRAIPSLSSSIPYSVPNSN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr158" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P22211-1.141.141", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P22211-1.150.150", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P22211-1.153.153", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P22211-1.154.154", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P22211-1.156.156", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P22211-1.159.159", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P22211-1.165.165", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P22211-1.167.167", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P22211-1.168.168", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P22211-1.169.169", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P22211-1.172.172", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P22211-1.173.173", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.159.159", "start_pos": 159, "end_pos": 159, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-06-19", "authors": "Smolka Marcus B, Albuquerque Claudio P, Chen Sheng-hong, Zhou Huilin", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GGSFAAQNRITSRLSTTSHT", "down_seq": "GRAIPSLSSSIPYSVPNSNK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser159" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P22211-1.141.141", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P22211-1.150.150", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P22211-1.153.153", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P22211-1.154.154", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P22211-1.156.156", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P22211-1.158.158", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P22211-1.165.165", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P22211-1.167.167", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P22211-1.168.168", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P22211-1.169.169", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P22211-1.172.172", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P22211-1.173.173", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.165.165", "start_pos": 165, "end_pos": 165, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QNRITSRLSTTSHTSGRAIP", "down_seq": "LSSSIPYSVPNSNKDNNSSN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser165" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P22211-1.150.150", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P22211-1.153.153", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P22211-1.154.154", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P22211-1.156.156", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P22211-1.158.158", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P22211-1.159.159", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P22211-1.167.167", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P22211-1.168.168", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P22211-1.169.169", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P22211-1.172.172", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P22211-1.173.173", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.167.167", "start_pos": 167, "end_pos": 167, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RITSRLSTTSHTSGRAIPSL", "down_seq": "SSIPYSVPNSNKDNNSSNSN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser167" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P22211-1.150.150", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P22211-1.153.153", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P22211-1.154.154", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P22211-1.156.156", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P22211-1.158.158", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P22211-1.159.159", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P22211-1.165.165", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P22211-1.168.168", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P22211-1.169.169", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P22211-1.172.172", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P22211-1.173.173", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.168.168", "start_pos": 168, "end_pos": 168, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ITSRLSTTSHTSGRAIPSLS", "down_seq": "SIPYSVPNSNKDNNSSNSNS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser168" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P22211-1.150.150", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P22211-1.153.153", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P22211-1.154.154", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P22211-1.156.156", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P22211-1.158.158", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P22211-1.159.159", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P22211-1.165.165", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P22211-1.167.167", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P22211-1.169.169", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P22211-1.172.172", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P22211-1.173.173", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.169.169", "start_pos": 169, "end_pos": 169, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Mol. Cell. Proteomics", "date": "2008", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "Global mapping of protein phosphorylation events identifies Ste20, Sch9 and the cell-cycle regulatory kinases Cdc28/Pho85 as mediators of fatty acid starvation responses in Saccharomyces cerevisiae.", "journal": "Molecular bioSystems", "date": "2012-03", "authors": "Pultz Dennis, Bennetzen Martin V, R\u00f8dk\u00e6r Steven Vestergaard, Zimmermann Christine, Enserink Jorrit M, Andersen Jens S, F\u00e6rgeman Nils J", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TSRLSTTSHTSGRAIPSLSS", "down_seq": "IPYSVPNSNKDNNSSNSNSS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser169" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P22211-1.150.150", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P22211-1.153.153", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P22211-1.154.154", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P22211-1.156.156", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P22211-1.158.158", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P22211-1.159.159", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P22211-1.165.165", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P22211-1.167.167", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P22211-1.168.168", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P22211-1.172.172", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P22211-1.173.173", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.172.172", "start_pos": 172, "end_pos": 172, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "LSTTSHTSGRAIPSLSSSIP", "down_seq": "SVPNSNKDNNSSNSNSSSLS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Tyr172" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P22211-1.153.153", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "downstream", "id": "P22211-1.154.154", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P22211-1.156.156", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P22211-1.158.158", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P22211-1.159.159", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P22211-1.165.165", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P22211-1.167.167", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P22211-1.168.168", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P22211-1.169.169", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P22211-1.173.173", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.173.173", "start_pos": 173, "end_pos": 173, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "STTSHTSGRAIPSLSSSIPY", "down_seq": "VPNSNKDNNSSNSNSSSLSS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser173" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P22211-1.153.153", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "downstream", "id": "P22211-1.154.154", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P22211-1.156.156", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P22211-1.158.158", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P22211-1.159.159", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P22211-1.165.165", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P22211-1.167.167", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P22211-1.168.168", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P22211-1.169.169", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P22211-1.172.172", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.20.20", "start_pos": 20, "end_pos": 20, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ], "crossref": [ { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "", "down_seq": "PRTSADTLTTTPESQSLDLH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ], "site_lbl": "Ser20" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P22211-1.0.0", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P22211-1.24.24", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P22211-1.27.27", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P22211-1.31.31", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.217.217", "start_pos": 217, "end_pos": 217, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ETYAGGMPNNISAIDSNVIS", "down_seq": "PKVDSVEPRFVISKQKLQKA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser217" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "upstream", "id": "P22211-1.222.222", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P22211-1.230.230", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.222.222", "start_pos": 222, "end_pos": 222, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GMPNNISAIDSNVISSPKVD", "down_seq": "VEPRFVISKQKLQKASMDSN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser222" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "P22211-1.217.217", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P22211-1.230.230", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P22211-1.238.238", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P22211-1.241.241", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.230.230", "start_pos": 230, "end_pos": 230, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IDSNVISSPKVDSVEPRFVI", "down_seq": "KQKLQKASMDSNNANATQSR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser230" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P22211-1.217.217", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P22211-1.222.222", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P22211-1.238.238", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P22211-1.241.241", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P22211-1.247.247", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P22211-1.249.249", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.238.238", "start_pos": 238, "end_pos": 238, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PKVDSVEPRFVISKQKLQKA", "down_seq": "MDSNNANATQSRSISRSGSF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser238" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P22211-1.222.222", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P22211-1.230.230", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P22211-1.241.241", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P22211-1.247.247", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P22211-1.249.249", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P22211-1.251.251", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P22211-1.253.253", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P22211-1.255.255", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P22211-1.257.257", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.241.241", "start_pos": 241, "end_pos": 241, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DSVEPRFVISKQKLQKASMD", "down_seq": "NNANATQSRSISRSGSFSSQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser241" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P22211-1.222.222", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P22211-1.230.230", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P22211-1.238.238", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P22211-1.247.247", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P22211-1.249.249", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P22211-1.251.251", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P22211-1.253.253", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P22211-1.255.255", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P22211-1.257.257", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P22211-1.259.259", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P22211-1.260.260", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.247.247", "start_pos": 247, "end_pos": 247, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "FVISKQKLQKASMDSNNANA", "down_seq": "QSRSISRSGSFSSQLGNFFF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr247" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P22211-1.230.230", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P22211-1.238.238", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P22211-1.241.241", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P22211-1.249.249", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P22211-1.251.251", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P22211-1.253.253", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P22211-1.255.255", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P22211-1.257.257", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P22211-1.259.259", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P22211-1.260.260", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.249.249", "start_pos": 249, "end_pos": 249, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Mol. Cell. Proteomics", "date": "2008", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast.", "journal": "Science signaling", "date": "2010-12-21", "authors": "Bodenmiller Bernd, Wanka Stefanie, Kraft Claudine, Urban J\u00f6rg, Campbell David, Pedrioli Patrick G, Gerrits Bertran, Picotti Paola, Lam Henry, Vitek Olga, Brusniak Mi-Youn, Roschitzki Bernd, Zhang Chao, Shokat Kevan M, Schlapbach Ralph, Colman-Lerner Alejandro, Nolan Garry P, Nesvizhskii Alexey I, Peter Matthias, Loewith Robbie, von Mering Christian, Aebersold Ruedi", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ISKQKLQKASMDSNNANATQ", "down_seq": "RSISRSGSFSSQLGNFFFSK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser249" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P22211-1.230.230", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P22211-1.238.238", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P22211-1.241.241", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P22211-1.247.247", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P22211-1.251.251", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P22211-1.253.253", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P22211-1.255.255", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P22211-1.257.257", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P22211-1.259.259", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P22211-1.260.260", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.24.24", "start_pos": 24, "end_pos": 24, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] } ], "crossref": [ { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LTRLLQEKRKNETSNSSPRT", "down_seq": "ADTLTTTPESQSLDLHSRNK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ], "site_lbl": "Ser24" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P22211-1.20.20", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P22211-1.27.27", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P22211-1.31.31", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.251.251", "start_pos": 251, "end_pos": 251, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KQKLQKASMDSNNANATQSR", "down_seq": "ISRSGSFSSQLGNFFFSKNS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser251" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P22211-1.238.238", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P22211-1.241.241", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P22211-1.247.247", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P22211-1.249.249", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P22211-1.253.253", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P22211-1.255.255", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P22211-1.257.257", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P22211-1.259.259", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P22211-1.260.260", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.253.253", "start_pos": 253, "end_pos": 253, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "crossref": [ { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KLQKASMDSNNANATQSRSI", "down_seq": "RSGSFSSQLGNFFFSKNSKE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Ser253" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P22211-1.238.238", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P22211-1.241.241", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P22211-1.247.247", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P22211-1.249.249", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P22211-1.251.251", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P22211-1.255.255", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P22211-1.257.257", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P22211-1.259.259", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P22211-1.260.260", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.255.255", "start_pos": 255, "end_pos": 255, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "Journal of proteome research", "date": "2007-03", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Mol. Cell. Proteomics", "date": "2008", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Identification of the rapamycin-sensitive phosphorylation sites within the Ser/Thr-rich domain of the yeast Npr1 protein kinase.", "journal": "Rapid communications in mass spectrometry : RCM", "date": "2008-12", "authors": "Gander Stefan, Bonenfant Debora, Altermatt Patrick, Martin Dietmar E, Hauri Simon, Moes Suzette, Hall Michael N, Jenoe Paul", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" } ] }, { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QKASMDSNNANATQSRSISR", "down_seq": "GSFSSQLGNFFFSKNSKESS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser255" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P22211-1.238.238", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P22211-1.241.241", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P22211-1.247.247", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P22211-1.249.249", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P22211-1.251.251", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P22211-1.253.253", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P22211-1.257.257", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P22211-1.259.259", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P22211-1.260.260", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.259.259", "start_pos": 259, "end_pos": 259, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of the rapamycin-sensitive phosphorylation sites within the Ser/Thr-rich domain of the yeast Npr1 protein kinase.", "journal": "Rapid communications in mass spectrometry : RCM", "date": "2008-12", "authors": "Gander Stefan, Bonenfant Debora, Altermatt Patrick, Martin Dietmar E, Hauri Simon, Moes Suzette, Hall Michael N, Jenoe Paul", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MDSNNANATQSRSISRSGSF", "down_seq": "SQLGNFFFSKNSKESSNSNS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser259" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P22211-1.241.241", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P22211-1.247.247", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P22211-1.249.249", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P22211-1.251.251", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P22211-1.253.253", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P22211-1.255.255", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P22211-1.257.257", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P22211-1.260.260", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.260.260", "start_pos": 260, "end_pos": 260, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of the rapamycin-sensitive phosphorylation sites within the Ser/Thr-rich domain of the yeast Npr1 protein kinase.", "journal": "Rapid communications in mass spectrometry : RCM", "date": "2008-12", "authors": "Gander Stefan, Bonenfant Debora, Altermatt Patrick, Martin Dietmar E, Hauri Simon, Moes Suzette, Hall Michael N, Jenoe Paul", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" } ] }, { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "Journal of proteome research", "date": "2007-03", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DSNNANATQSRSISRSGSFS", "down_seq": "QLGNFFFSKNSKESSNSNSA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser260" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P22211-1.241.241", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P22211-1.247.247", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P22211-1.249.249", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P22211-1.251.251", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P22211-1.253.253", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P22211-1.255.255", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P22211-1.257.257", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P22211-1.259.259", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.27.27", "start_pos": 27, "end_pos": 27, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "LLQEKRKNETSNSSPRTSAD", "down_seq": "LTTTPESQSLDLHSRNKSSS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr27" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P22211-1.20.20", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P22211-1.24.24", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P22211-1.31.31", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P22211-1.45.45", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P22211-1.46.46", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P22211-1.47.47", "categories": [ "glycosylation_flag", "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.288.288", "start_pos": 288, "end_pos": 288, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of the rapamycin-sensitive phosphorylation sites within the Ser/Thr-rich domain of the yeast Npr1 protein kinase.", "journal": "Rapid communications in mass spectrometry : RCM", "date": "2008-12", "authors": "Gander Stefan, Bonenfant Debora, Altermatt Patrick, Martin Dietmar E, Hauri Simon, Moes Suzette, Hall Michael N, Jenoe Paul", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" } ] } ], "crossref": [ { "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SKNSKESSNSNSAGMSFSAN", "down_seq": "NGPSPNIKNPNVTNGSTPIP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" } ], "site_lbl": "Ser288" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "P22211-1.292.292", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P22211-1.301.301", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P22211-1.304.304", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P22211-1.305.305", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.292.292", "start_pos": 292, "end_pos": 292, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of the rapamycin-sensitive phosphorylation sites within the Ser/Thr-rich domain of the yeast Npr1 protein kinase.", "journal": "Rapid communications in mass spectrometry : RCM", "date": "2008-12", "authors": "Gander Stefan, Bonenfant Debora, Altermatt Patrick, Martin Dietmar E, Hauri Simon, Moes Suzette, Hall Michael N, Jenoe Paul", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KESSNSNSAGMSFSANSNGP", "down_seq": "PNIKNPNVTNGSTPIPKPIR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser292" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P22211-1.288.288", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P22211-1.301.301", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P22211-1.304.304", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P22211-1.305.305", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.301.301", "start_pos": 301, "end_pos": 301, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "GMSFSANSNGPSPNIKNPNV", "down_seq": "NGSTPIPKPIRARQSSIYSA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr301" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P22211-1.288.288", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P22211-1.292.292", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P22211-1.304.304", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P22211-1.305.305", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P22211-1.316.316", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P22211-1.317.317", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P22211-1.320.320", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.304.304", "start_pos": 304, "end_pos": 304, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FSANSNGPSPNIKNPNVTNG", "down_seq": "TPIPKPIRARQSSIYSASRQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser304" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P22211-1.288.288", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P22211-1.292.292", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P22211-1.301.301", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P22211-1.305.305", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P22211-1.316.316", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P22211-1.317.317", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P22211-1.320.320", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P22211-1.322.322", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.305.305", "start_pos": 305, "end_pos": 305, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SANSNGPSPNIKNPNVTNGS", "down_seq": "PIPKPIRARQSSIYSASRQP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr305" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P22211-1.288.288", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P22211-1.292.292", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P22211-1.301.301", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P22211-1.304.304", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P22211-1.316.316", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P22211-1.317.317", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P22211-1.320.320", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P22211-1.322.322", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.316.316", "start_pos": 316, "end_pos": 316, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KNPNVTNGSTPIPKPIRARQ", "down_seq": "SIYSASRQPTGSYTDNFYGS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser316" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P22211-1.301.301", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P22211-1.304.304", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P22211-1.305.305", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P22211-1.317.317", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P22211-1.320.320", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P22211-1.322.322", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P22211-1.326.326", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P22211-1.328.328", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P22211-1.330.330", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P22211-1.334.334", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P22211-1.336.336", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.317.317", "start_pos": 317, "end_pos": 317, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of the rapamycin-sensitive phosphorylation sites within the Ser/Thr-rich domain of the yeast Npr1 protein kinase.", "journal": "Rapid communications in mass spectrometry : RCM", "date": "2008-12", "authors": "Gander Stefan, Bonenfant Debora, Altermatt Patrick, Martin Dietmar E, Hauri Simon, Moes Suzette, Hall Michael N, Jenoe Paul", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" } ] }, { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "Journal of proteome research", "date": "2007-03", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae.", "journal": "Nature biotechnology", "date": "2002-03", "authors": "Ficarro Scott B, McCleland Mark L, Stukenberg P Todd, Burke Daniel J, Ross Mark M, Shabanowitz Jeffrey, Hunt Donald F, White Forest M", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NPNVTNGSTPIPKPIRARQS", "down_seq": "IYSASRQPTGSYTDNFYGSP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser317" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P22211-1.301.301", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P22211-1.304.304", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P22211-1.305.305", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P22211-1.316.316", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P22211-1.320.320", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P22211-1.322.322", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P22211-1.326.326", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P22211-1.328.328", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P22211-1.330.330", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P22211-1.334.334", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P22211-1.336.336", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 7 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.31.31", "start_pos": 31, "end_pos": 31, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "KRKNETSNSSPRTSADTLTT", "down_seq": "PESQSLDLHSRNKSSSHIGS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr31" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P22211-1.20.20", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P22211-1.24.24", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P22211-1.27.27", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P22211-1.45.45", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P22211-1.46.46", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P22211-1.47.47", "categories": [ "glycosylation_flag", "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P22211-1.51.51", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.320.320", "start_pos": 320, "end_pos": 320, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of the rapamycin-sensitive phosphorylation sites within the Ser/Thr-rich domain of the yeast Npr1 protein kinase.", "journal": "Rapid communications in mass spectrometry : RCM", "date": "2008-12", "authors": "Gander Stefan, Bonenfant Debora, Altermatt Patrick, Martin Dietmar E, Hauri Simon, Moes Suzette, Hall Michael N, Jenoe Paul", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" } ] }, { "title": "Global mapping of protein phosphorylation events identifies Ste20, Sch9 and the cell-cycle regulatory kinases Cdc28/Pho85 as mediators of fatty acid starvation responses in Saccharomyces cerevisiae.", "journal": "Molecular bioSystems", "date": "2012-03", "authors": "Pultz Dennis, Bennetzen Martin V, R\u00f8dk\u00e6r Steven Vestergaard, Zimmermann Christine, Enserink Jorrit M, Andersen Jens S, F\u00e6rgeman Nils J", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VTNGSTPIPKPIRARQSSIY", "down_seq": "ASRQPTGSYTDNFYGSPSSV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser320" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P22211-1.301.301", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P22211-1.304.304", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P22211-1.305.305", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P22211-1.316.316", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P22211-1.317.317", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P22211-1.322.322", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P22211-1.326.326", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P22211-1.328.328", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P22211-1.330.330", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P22211-1.334.334", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P22211-1.336.336", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P22211-1.338.338", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P22211-1.339.339", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.322.322", "start_pos": 322, "end_pos": 322, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NGSTPIPKPIRARQSSIYSA", "down_seq": "RQPTGSYTDNFYGSPSSVHD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser322" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P22211-1.304.304", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P22211-1.305.305", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P22211-1.316.316", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P22211-1.317.317", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P22211-1.320.320", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P22211-1.326.326", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P22211-1.328.328", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P22211-1.330.330", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P22211-1.334.334", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P22211-1.336.336", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P22211-1.338.338", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P22211-1.339.339", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.326.326", "start_pos": 326, "end_pos": 326, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PIPKPIRARQSSIYSASRQP", "down_seq": "GSYTDNFYGSPSSVHDHLPP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr326" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "P22211-1.316.316", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P22211-1.317.317", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P22211-1.320.320", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P22211-1.322.322", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P22211-1.328.328", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P22211-1.330.330", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P22211-1.334.334", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P22211-1.336.336", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P22211-1.338.338", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P22211-1.339.339", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.328.328", "start_pos": 328, "end_pos": 328, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of the rapamycin-sensitive phosphorylation sites within the Ser/Thr-rich domain of the yeast Npr1 protein kinase.", "journal": "Rapid communications in mass spectrometry : RCM", "date": "2008-12", "authors": "Gander Stefan, Bonenfant Debora, Altermatt Patrick, Martin Dietmar E, Hauri Simon, Moes Suzette, Hall Michael N, Jenoe Paul", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PKPIRARQSSIYSASRQPTG", "down_seq": "YTDNFYGSPSSVHDHLPPSQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser328" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P22211-1.316.316", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P22211-1.317.317", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P22211-1.320.320", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P22211-1.322.322", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P22211-1.326.326", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P22211-1.330.330", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P22211-1.334.334", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P22211-1.336.336", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P22211-1.338.338", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P22211-1.339.339", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P22211-1.347.347", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.330.330", "start_pos": 330, "end_pos": 330, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PIRARQSSIYSASRQPTGSY", "down_seq": "DNFYGSPSSVHDHLPPSQSV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr330" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "P22211-1.316.316", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P22211-1.317.317", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P22211-1.320.320", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P22211-1.322.322", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P22211-1.326.326", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P22211-1.328.328", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P22211-1.334.334", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P22211-1.336.336", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P22211-1.338.338", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P22211-1.339.339", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P22211-1.347.347", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P22211-1.349.349", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.334.334", "start_pos": 334, "end_pos": 334, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "RQSSIYSASRQPTGSYTDNF", "down_seq": "GSPSSVHDHLPPSQSVPRSQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Tyr334" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P22211-1.316.316", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P22211-1.317.317", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P22211-1.320.320", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P22211-1.322.322", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P22211-1.326.326", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P22211-1.328.328", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P22211-1.330.330", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P22211-1.336.336", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P22211-1.338.338", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P22211-1.339.339", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P22211-1.347.347", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P22211-1.349.349", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P22211-1.353.353", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.336.336", "start_pos": 336, "end_pos": 336, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of the rapamycin-sensitive phosphorylation sites within the Ser/Thr-rich domain of the yeast Npr1 protein kinase.", "journal": "Rapid communications in mass spectrometry : RCM", "date": "2008-12", "authors": "Gander Stefan, Bonenfant Debora, Altermatt Patrick, Martin Dietmar E, Hauri Simon, Moes Suzette, Hall Michael N, Jenoe Paul", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SSIYSASRQPTGSYTDNFYG", "down_seq": "PSSVHDHLPPSQSVPRSQHS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser336" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P22211-1.316.316", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "downstream", "id": "P22211-1.317.317", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P22211-1.320.320", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P22211-1.322.322", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P22211-1.326.326", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P22211-1.328.328", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P22211-1.330.330", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P22211-1.334.334", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P22211-1.338.338", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P22211-1.339.339", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P22211-1.347.347", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P22211-1.349.349", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P22211-1.353.353", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P22211-1.356.356", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.338.338", "start_pos": 338, "end_pos": 338, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of the rapamycin-sensitive phosphorylation sites within the Ser/Thr-rich domain of the yeast Npr1 protein kinase.", "journal": "Rapid communications in mass spectrometry : RCM", "date": "2008-12", "authors": "Gander Stefan, Bonenfant Debora, Altermatt Patrick, Martin Dietmar E, Hauri Simon, Moes Suzette, Hall Michael N, Jenoe Paul", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] } ], "crossref": [ { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IYSASRQPTGSYTDNFYGSP", "down_seq": "SVHDHLPPSQSVPRSQHSSI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" } ], "site_lbl": "Ser338" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P22211-1.320.320", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P22211-1.322.322", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P22211-1.326.326", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P22211-1.328.328", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P22211-1.330.330", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P22211-1.334.334", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P22211-1.336.336", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P22211-1.339.339", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P22211-1.347.347", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P22211-1.349.349", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P22211-1.353.353", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P22211-1.356.356", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P22211-1.357.357", "categories": [ "glycosylation_flag", "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.339.339", "start_pos": 339, "end_pos": 339, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of the rapamycin-sensitive phosphorylation sites within the Ser/Thr-rich domain of the yeast Npr1 protein kinase.", "journal": "Rapid communications in mass spectrometry : RCM", "date": "2008-12", "authors": "Gander Stefan, Bonenfant Debora, Altermatt Patrick, Martin Dietmar E, Hauri Simon, Moes Suzette, Hall Michael N, Jenoe Paul", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] } ], "crossref": [ { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "YSASRQPTGSYTDNFYGSPS", "down_seq": "VHDHLPPSQSVPRSQHSSIG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" } ], "site_lbl": "Ser339" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P22211-1.320.320", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P22211-1.322.322", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P22211-1.326.326", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P22211-1.328.328", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P22211-1.330.330", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P22211-1.334.334", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P22211-1.336.336", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P22211-1.338.338", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P22211-1.347.347", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P22211-1.349.349", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P22211-1.353.353", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P22211-1.356.356", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P22211-1.357.357", "categories": [ "glycosylation_flag", "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.347.347", "start_pos": 347, "end_pos": 347, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of the rapamycin-sensitive phosphorylation sites within the Ser/Thr-rich domain of the yeast Npr1 protein kinase.", "journal": "Rapid communications in mass spectrometry : RCM", "date": "2008-12", "authors": "Gander Stefan, Bonenfant Debora, Altermatt Patrick, Martin Dietmar E, Hauri Simon, Moes Suzette, Hall Michael N, Jenoe Paul", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" } ] }, { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] } ], "crossref": [ { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GSYTDNFYGSPSSVHDHLPP", "down_seq": "QSVPRSQHSSIGDLKRFFKK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ], "site_lbl": "Ser347" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P22211-1.328.328", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P22211-1.330.330", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P22211-1.334.334", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P22211-1.336.336", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P22211-1.338.338", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P22211-1.339.339", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P22211-1.349.349", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P22211-1.353.353", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P22211-1.356.356", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P22211-1.357.357", "categories": [ "glycosylation_flag", "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.349.349", "start_pos": 349, "end_pos": 349, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of the rapamycin-sensitive phosphorylation sites within the Ser/Thr-rich domain of the yeast Npr1 protein kinase.", "journal": "Rapid communications in mass spectrometry : RCM", "date": "2008-12", "authors": "Gander Stefan, Bonenfant Debora, Altermatt Patrick, Martin Dietmar E, Hauri Simon, Moes Suzette, Hall Michael N, Jenoe Paul", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" } ] } ], "crossref": [ { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "YTDNFYGSPSSVHDHLPPSQ", "down_seq": "VPRSQHSSIGDLKRFFKKSS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" } ], "site_lbl": "Ser349" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P22211-1.330.330", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P22211-1.334.334", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P22211-1.336.336", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P22211-1.338.338", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P22211-1.339.339", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P22211-1.347.347", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P22211-1.353.353", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P22211-1.356.356", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P22211-1.357.357", "categories": [ "glycosylation_flag", "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P22211-1.369.369", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.369.369", "start_pos": 369, "end_pos": 369, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SVPRSQHSSIGDLKRFFKKS", "down_seq": "NSNLSSNSNNVIPNGSPLSS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser369" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P22211-1.349.349", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P22211-1.353.353", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P22211-1.356.356", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P22211-1.357.357", "categories": [ "glycosylation_flag", "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P22211-1.385.385", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.385.385", "start_pos": 385, "end_pos": 385, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of the rapamycin-sensitive phosphorylation sites within the Ser/Thr-rich domain of the yeast Npr1 protein kinase.", "journal": "Rapid communications in mass spectrometry : RCM", "date": "2008-12", "authors": "Gander Stefan, Bonenfant Debora, Altermatt Patrick, Martin Dietmar E, Hauri Simon, Moes Suzette, Hall Michael N, Jenoe Paul", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FKKSSNSNLSSNSNNVIPNG", "down_seq": "PLSSGIAVPSHSHSSSHFAA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser385" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P22211-1.369.369", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P22211-1.399.399", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.399.399", "start_pos": 399, "end_pos": 399, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NVIPNGSPLSSGIAVPSHSH", "down_seq": "SSHFAAGNNSYSTSYNGNGD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser399" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "P22211-1.385.385", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.425.425", "start_pos": 425, "end_pos": 425, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AGNNSYSTSYNGNGDTIYSH", "down_seq": "HGGSGIPFSKRYIKTGADLG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser425" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.451.451", "start_pos": 451, "end_pos": 451, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IPFSKRYIKTGADLGAGAGG", "down_seq": "VKLAQRISDNKIFAVKEFRT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser451" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.662.662", "start_pos": 662, "end_pos": 662, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KIPKLRDNSFKLFCSGRDCD", "down_seq": "LSSLVTRTPDPPSYDESHST", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser662" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "upstream", "id": "P22211-1.675.675", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P22211-1.681.681", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.675.675", "start_pos": 675, "end_pos": 675, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "CSGRDCDSLSSLVTRTPDPP", "down_seq": "YDESHSTEKKKPESSSNNVS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser675" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P22211-1.662.662", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P22211-1.681.681", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.681.681", "start_pos": 681, "end_pos": 681, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Mol. Cell. Proteomics", "date": "2008", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DSLSSLVTRTPDPPSYDESH", "down_seq": "TEKKKPESSSNNVSDPNNVN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser681" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P22211-1.662.662", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P22211-1.675.675", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.85.85", "start_pos": 85, "end_pos": 85, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of the rapamycin-sensitive phosphorylation sites within the Ser/Thr-rich domain of the yeast Npr1 protein kinase.", "journal": "Rapid communications in mass spectrometry : RCM", "date": "2008-12", "authors": "Gander Stefan, Bonenfant Debora, Altermatt Patrick, Martin Dietmar E, Hauri Simon, Moes Suzette, Hall Michael N, Jenoe Paul", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" } ] } ], "crossref": [ { "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VPVPGSVTTVTQIYSEEDSS", "down_seq": "TAGSSLDDRNQFSSSFLNAN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" } ], "site_lbl": "Ser85" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "P22211-1.89.89", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P22211-1.90.90", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P22211-1.100.100", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.89.89", "start_pos": 89, "end_pos": 89, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GSVTTVTQIYSEEDSSSTAG", "down_seq": "SLDDRNQFSSSFLNANFAHT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser89" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P22211-1.85.85", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P22211-1.90.90", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P22211-1.100.100", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22211-1.90.90", "start_pos": 90, "end_pos": 90, "uniprot_canonical_ac": "P22211-1", "length": 790, "uniprot_id": "NPR1_YEAST", "protein_name": "Nitrogen permease reactivator protein", "refseq_ac": "NP_014216", "refseq_name": "serine/threonine protein kinase NPR1", "gene_name": "NPR1", "gene_names_uniprotkb": "NPR1; N1631", "gene_names_refseq": "NPR1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of the rapamycin-sensitive phosphorylation sites within the Ser/Thr-rich domain of the yeast Npr1 protein kinase.", "journal": "Rapid communications in mass spectrometry : RCM", "date": "2008-12", "authors": "Gander Stefan, Bonenfant Debora, Altermatt Patrick, Martin Dietmar E, Hauri Simon, Moes Suzette, Hall Michael N, Jenoe Paul", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SVTTVTQIYSEEDSSSTAGS", "down_seq": "LDDRNQFSSSFLNANFAHTA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P22211", "url": "https://www.uniprot.org/uniprotkb/P22211" }, { "database": "PubMed", "id": "18980262", "url": "https://glygen.org/publication/PubMed/18980262" }, { "database": "iPTMnet", "id": "P22211", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22211" }, { "database": "SGD", "id": "S000005127", "url": "https://www.yeastgenome.org/locus/S000005127" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser90" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "257", "end_pos": "257" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "47", "end_pos": "47" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "111", "end_pos": "111" }, { "start_pos": "113", "end_pos": "113" }, { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "132", "end_pos": "132" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "150", "end_pos": "150" }, { "start_pos": "153", "end_pos": "153" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "156", "end_pos": "156" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "168", "end_pos": "168" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "259", "end_pos": "259" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "304", "end_pos": "304" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "316", "end_pos": "316" }, { "start_pos": "317", "end_pos": "317" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "322", "end_pos": "322" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "328", "end_pos": "328" }, { "start_pos": "330", "end_pos": "330" }, { "start_pos": "334", "end_pos": "334" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "347", "end_pos": "347" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "385", "end_pos": "385" }, { "start_pos": "399", "end_pos": "399" }, { "start_pos": "425", "end_pos": "425" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "662", "end_pos": "662" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "85", "end_pos": "85" }, { "start_pos": "89", "end_pos": "89" }, { "start_pos": "90", "end_pos": "90" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "P22211-1.85.85", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P22211-1.89.89", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P22211-1.100.100", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22214-1.160.160", "start_pos": 160, "end_pos": 160, "uniprot_canonical_ac": "P22214-1", "length": 214, "uniprot_id": "SEC22_YEAST", "protein_name": "Protein transport protein SEC22", "refseq_ac": "NP_013370", "refseq_name": "SNAP receptor SEC22", "gene_name": "SEC22", "gene_names_uniprotkb": "SEC22; L8479.3; SLY2; TSL26", "gene_names_refseq": "SEC22; SLY2; TS26; TSL26", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22214", "url": "https://www.uniprot.org/uniprotkb/P22214" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P22214", "url": "https://www.uniprot.org/uniprotkb/P22214" }, { "database": "iPTMnet", "id": "P22214", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22214" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22214", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22214" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22214", "url": "https://www.uniprot.org/uniprotkb/P22214", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22214", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22214", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000004258", "url": "https://www.yeastgenome.org/locus/S000004258", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LVGVKQIMSKNIEDLLYRGD", "down_seq": "LDKMSDMSSSLKETSKRYRK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P22214", "url": "https://www.uniprot.org/uniprotkb/P22214" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P22214", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22214" }, { "database": "SGD", "id": "S000004258", "url": "https://www.yeastgenome.org/locus/S000004258" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser160" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "160", "end_pos": "160" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "upstream", "id": "P22214-1.165.165", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P22214-1.169.169", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22214-1.165.165", "start_pos": 165, "end_pos": 165, "uniprot_canonical_ac": "P22214-1", "length": 214, "uniprot_id": "SEC22_YEAST", "protein_name": "Protein transport protein SEC22", "refseq_ac": "NP_013370", "refseq_name": "SNAP receptor SEC22", "gene_name": "SEC22", "gene_names_uniprotkb": "SEC22; L8479.3; SLY2; TSL26", "gene_names_refseq": "SEC22; SLY2; TS26; TSL26", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22214", "url": "https://www.uniprot.org/uniprotkb/P22214" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22214", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22214" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004258", "url": "https://www.yeastgenome.org/locus/S000004258", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22214", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22214", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QIMSKNIEDLLYRGDSLDKM", "down_seq": "DMSSSLKETSKRYRKSAQKI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004258", "url": "https://www.yeastgenome.org/locus/S000004258" }, { "database": "iPTMnet", "id": "P22214", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22214" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser165" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "160", "end_pos": "160" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "P22214-1.160.160", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P22214-1.169.169", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22214-1.169.169", "start_pos": 169, "end_pos": 169, "uniprot_canonical_ac": "P22214-1", "length": 214, "uniprot_id": "SEC22_YEAST", "protein_name": "Protein transport protein SEC22", "refseq_ac": "NP_013370", "refseq_name": "SNAP receptor SEC22", "gene_name": "SEC22", "gene_names_uniprotkb": "SEC22; L8479.3; SLY2; TSL26", "gene_names_refseq": "SEC22; SLY2; TS26; TSL26", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22214", "url": "https://www.uniprot.org/uniprotkb/P22214" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22214", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22214" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004258", "url": "https://www.yeastgenome.org/locus/S000004258", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22214", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22214", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KNIEDLLYRGDSLDKMSDMS", "down_seq": "SLKETSKRYRKSAQKINFDL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004258", "url": "https://www.yeastgenome.org/locus/S000004258" }, { "database": "iPTMnet", "id": "P22214", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22214" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser169" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "160", "end_pos": "160" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "169", "end_pos": "169" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "P22214-1.160.160", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P22214-1.165.165", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22219-1.1261.1261", "start_pos": 1261, "end_pos": 1261, "uniprot_canonical_ac": "P22219-1", "length": 1454, "uniprot_id": "VPS15_YEAST", "protein_name": "Serine/threonine-protein kinase VPS15", "refseq_ac": "NP_009655", "refseq_name": "ubiquitin-binding serine/threonine protein kinase VPS15", "gene_name": "VPS15", "gene_names_uniprotkb": "VPS15; GRD8; VAC4; VPL19; YBR0825", "gene_names_refseq": "GRD8; VAC4; VPL19; VPS15; VPS40; VPT15", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Structure and function of Vps15 in the endosomal G protein signaling pathway.", "journal": "Biochemistry", "date": "2009-07-14", "authors": "Heenan Erin J, Vanhooke Janeen L, Temple Brenda R, Betts Laurie, Sondek John E, Dohlman Henrik G", "evidence": [ { "database": "UniProtKB", "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219" } ], "reference": [ { "type": "PubMed", "id": "19445518", "url": "https://glygen.org/publication/PubMed/19445518" } ] } ], "crossref": [ { "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19445518", "url": "https://glygen.org/publication/PubMed/19445518", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "EECCVLILGTTRGIIDIWDI", "down_seq": "FNVLIRSWSFGDHAPITHVE", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Diminishes the interaction with GPA1.", "evidence": [ { "database": "UniProtKB", "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219" }, { "database": "PubMed", "id": "19445518", "url": "https://glygen.org/publication/PubMed/19445518" } ] }, { "sequence_org": "R", "sequence_mut": "K", "comment": "Diminishes the interaction with GPA1.", "evidence": [ { "database": "UniProtKB", "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219" }, { "database": "PubMed", "id": "19445518", "url": "https://glygen.org/publication/PubMed/19445518" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1261", "end_pos": "1261" }, { "start_pos": "147", "end_pos": "147" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "54", "end_pos": "54" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1385", "end_pos": "1385" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "904", "end_pos": "904" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22219-1.147.147", "start_pos": 147, "end_pos": 147, "uniprot_canonical_ac": "P22219-1", "length": 1454, "uniprot_id": "VPS15_YEAST", "protein_name": "Serine/threonine-protein kinase VPS15", "refseq_ac": "NP_009655", "refseq_name": "ubiquitin-binding serine/threonine protein kinase VPS15", "gene_name": "VPS15", "gene_names_uniprotkb": "VPS15; GRD8; VAC4; VPL19; YBR0825", "gene_names_refseq": "GRD8; VAC4; VPL19; VPS15; VPS40; VPT15", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A genetic and structural analysis of the yeast Vps15 protein kinase: evidence for a direct role of Vps15p in vacuolar protein delivery.", "journal": "The EMBO journal", "date": "1991-12", "authors": "Herman P K, Stack J H, Emr S D", "evidence": [ { "database": "UniProtKB", "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219" } ], "reference": [ { "type": "PubMed", "id": "1756716", "url": "https://glygen.org/publication/PubMed/1756716" } ] } ], "crossref": [ { "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "1756716", "url": "https://glygen.org/publication/PubMed/1756716", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "IAFQLLNALKDIHNLNIVHG", "down_seq": "IKTENILVTSWNWCILTDFA", "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "R", "comment": "Loss of activity.", "evidence": [ { "database": "UniProtKB", "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219" }, { "database": "PubMed", "id": "1756716", "url": "https://glygen.org/publication/PubMed/1756716" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1261", "end_pos": "1261" }, { "start_pos": "147", "end_pos": "147" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "54", "end_pos": "54" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1385", "end_pos": "1385" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "904", "end_pos": "904" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P22219-1.149.149", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P22219-1.151.151", "categories": [ "mutagenesis_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P22219-1.165.165", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22219-1.149.149", "start_pos": 149, "end_pos": 149, "uniprot_canonical_ac": "P22219-1", "length": 1454, "uniprot_id": "VPS15_YEAST", "protein_name": "Serine/threonine-protein kinase VPS15", "refseq_ac": "NP_009655", "refseq_name": "ubiquitin-binding serine/threonine protein kinase VPS15", "gene_name": "VPS15", "gene_names_uniprotkb": "VPS15; GRD8; VAC4; VPL19; YBR0825", "gene_names_refseq": "GRD8; VAC4; VPL19; VPS15; VPS40; VPT15", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A genetic and structural analysis of the yeast Vps15 protein kinase: evidence for a direct role of Vps15p in vacuolar protein delivery.", "journal": "The EMBO journal", "date": "1991-12", "authors": "Herman P K, Stack J H, Emr S D", "evidence": [ { "database": "UniProtKB", "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219" } ], "reference": [ { "type": "PubMed", "id": "1756716", "url": "https://glygen.org/publication/PubMed/1756716" } ] } ], "crossref": [ { "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "1756716", "url": "https://glygen.org/publication/PubMed/1756716", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "FQLLNALKDIHNLNIVHGDI", "down_seq": "TENILVTSWNWCILTDFAAF", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "D", "comment": "Loss of activity.", "evidence": [ { "database": "UniProtKB", "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219" }, { "database": "PubMed", "id": "1756716", "url": "https://glygen.org/publication/PubMed/1756716" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1261", "end_pos": "1261" }, { "start_pos": "147", "end_pos": "147" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "54", "end_pos": "54" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1385", "end_pos": "1385" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "904", "end_pos": "904" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P22219-1.147.147", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P22219-1.151.151", "categories": [ "mutagenesis_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P22219-1.165.165", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22219-1.151.151", "start_pos": 151, "end_pos": 151, "uniprot_canonical_ac": "P22219-1", "length": 1454, "uniprot_id": "VPS15_YEAST", "protein_name": "Serine/threonine-protein kinase VPS15", "refseq_ac": "NP_009655", "refseq_name": "ubiquitin-binding serine/threonine protein kinase VPS15", "gene_name": "VPS15", "gene_names_uniprotkb": "VPS15; GRD8; VAC4; VPL19; YBR0825", "gene_names_refseq": "GRD8; VAC4; VPL19; VPS15; VPS40; VPT15", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A genetic and structural analysis of the yeast Vps15 protein kinase: evidence for a direct role of Vps15p in vacuolar protein delivery.", "journal": "The EMBO journal", "date": "1991-12", "authors": "Herman P K, Stack J H, Emr S D", "evidence": [ { "database": "UniProtKB", "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219" } ], "reference": [ { "type": "PubMed", "id": "1756716", "url": "https://glygen.org/publication/PubMed/1756716" } ] } ], "crossref": [ { "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "1756716", "url": "https://glygen.org/publication/PubMed/1756716", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "E", "start_aa": "E", "up_seq": "LLNALKDIHNLNIVHGDIKT", "down_seq": "NILVTSWNWCILTDFAAFIK", "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "R", "comment": "Modest effect on activity and normal CPY sorting.", "evidence": [ { "database": "UniProtKB", "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219" }, { "database": "PubMed", "id": "1756716", "url": "https://glygen.org/publication/PubMed/1756716" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1261", "end_pos": "1261" }, { "start_pos": "147", "end_pos": "147" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "54", "end_pos": "54" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1385", "end_pos": "1385" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "904", "end_pos": "904" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P22219-1.147.147", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P22219-1.149.149", "categories": [ "mutagenesis_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P22219-1.165.165", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22219-1.165.165", "start_pos": 165, "end_pos": 165, "uniprot_canonical_ac": "P22219-1", "length": 1454, "uniprot_id": "VPS15_YEAST", "protein_name": "Serine/threonine-protein kinase VPS15", "refseq_ac": "NP_009655", "refseq_name": "ubiquitin-binding serine/threonine protein kinase VPS15", "gene_name": "VPS15", "gene_names_uniprotkb": "VPS15; GRD8; VAC4; VPL19; YBR0825", "gene_names_refseq": "GRD8; VAC4; VPL19; VPS15; VPS40; VPT15", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A novel protein kinase homolog essential for protein sorting to the yeast lysosome-like vacuole.", "journal": "Cell", "date": "1991-01-25", "authors": "Herman P K, Stack J H, DeModena J A, Emr S D", "evidence": [ { "database": "UniProtKB", "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219" } ], "reference": [ { "type": "PubMed", "id": "1988155", "url": "https://glygen.org/publication/PubMed/1988155" } ] } ], "crossref": [ { "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "1988155", "url": "https://glygen.org/publication/PubMed/1988155", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "HGDIKTENILVTSWNWCILT", "down_seq": "FAAFIKPVYLPEDNPGEFLF", "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "R", "comment": "Loss of activity.", "evidence": [ { "database": "UniProtKB", "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219" }, { "database": "PubMed", "id": "1988155", "url": "https://glygen.org/publication/PubMed/1988155" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1261", "end_pos": "1261" }, { "start_pos": "147", "end_pos": "147" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "54", "end_pos": "54" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1385", "end_pos": "1385" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "904", "end_pos": "904" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P22219-1.147.147", "categories": [ "mutagenesis_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P22219-1.149.149", "categories": [ "mutagenesis_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P22219-1.151.151", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22219-1.200.200", "start_pos": 200, "end_pos": 200, "uniprot_canonical_ac": "P22219-1", "length": 1454, "uniprot_id": "VPS15_YEAST", "protein_name": "Serine/threonine-protein kinase VPS15", "refseq_ac": "NP_009655", "refseq_name": "ubiquitin-binding serine/threonine protein kinase VPS15", "gene_name": "VPS15", "gene_names_uniprotkb": "VPS15; GRD8; VAC4; VPL19; YBR0825", "gene_names_refseq": "GRD8; VAC4; VPL19; VPS15; VPS40; VPT15", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A novel protein kinase homolog essential for protein sorting to the yeast lysosome-like vacuole.", "journal": "Cell", "date": "1991-01-25", "authors": "Herman P K, Stack J H, DeModena J A, Emr S D", "evidence": [ { "database": "UniProtKB", "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219" } ], "reference": [ { "type": "PubMed", "id": "1988155", "url": "https://glygen.org/publication/PubMed/1988155" } ] }, { "title": "A membrane-associated complex containing the Vps15 protein kinase and the Vps34 PI 3-kinase is essential for protein sorting to the yeast lysosome-like vacuole.", "journal": "The EMBO journal", "date": "1993-05", "authors": "Stack J H, Herman P K, Schu P V, Emr S D", "evidence": [ { "database": "UniProtKB", "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219" } ], "reference": [ { "type": "PubMed", "id": "8387919", "url": "https://glygen.org/publication/PubMed/8387919" } ] } ], "crossref": [ { "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "1988155", "url": "https://glygen.org/publication/PubMed/1988155", "database": "PubMed", "categories": [ "Other" ] }, { "id": "8387919", "url": "https://glygen.org/publication/PubMed/8387919", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "E", "start_aa": "E", "up_seq": "PGEFLFYFDTSKRRTCYLAP", "down_seq": "RFNSKLYQDGKSNNGRLTKE", "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "R", "comment": "Loss of activity. No activation of VPS34 kinase activity.", "evidence": [ { "database": "UniProtKB", "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219" }, { "database": "PubMed", "id": "1988155", "url": "https://glygen.org/publication/PubMed/1988155" }, { "database": "PubMed", "id": "8387919", "url": "https://glygen.org/publication/PubMed/8387919" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1261", "end_pos": "1261" }, { "start_pos": "147", "end_pos": "147" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "54", "end_pos": "54" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1385", "end_pos": "1385" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "904", "end_pos": "904" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22219-1.2.2", "start_pos": 2, "end_pos": 2, "uniprot_canonical_ac": "P22219-1", "length": 1454, "uniprot_id": "VPS15_YEAST", "protein_name": "Serine/threonine-protein kinase VPS15", "refseq_ac": "NP_009655", "refseq_name": "ubiquitin-binding serine/threonine protein kinase VPS15", "gene_name": "VPS15", "gene_names_uniprotkb": "VPS15; GRD8; VAC4; VPL19; YBR0825", "gene_names_refseq": "GRD8; VAC4; VPL19; VPS15; VPS40; VPT15", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A genetic and structural analysis of the yeast Vps15 protein kinase: evidence for a direct role of Vps15p in vacuolar protein delivery.", "journal": "The EMBO journal", "date": "1991-12", "authors": "Herman P K, Stack J H, Emr S D", "evidence": [ { "database": "UniProtKB", "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219" } ], "reference": [ { "type": "PubMed", "id": "1756716", "url": "https://glygen.org/publication/PubMed/1756716" } ] } ], "crossref": [ { "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "1756716", "url": "https://glygen.org/publication/PubMed/1756716", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "G", "start_aa": "G", "up_seq": "M", "down_seq": "AQLSLVVQASPSIAIFSYID", "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "A", "comment": "No myristoylation, but still membrane-association and normal activity.", "evidence": [ { "database": "UniProtKB", "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219" }, { "database": "PubMed", "id": "1756716", "url": "https://glygen.org/publication/PubMed/1756716" } ] }, { "sequence_org": "G", "sequence_mut": "W", "comment": "No myristoylation, but still membrane-association and normal activity.", "evidence": [ { "database": "UniProtKB", "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219" }, { "database": "PubMed", "id": "1756716", "url": "https://glygen.org/publication/PubMed/1756716" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1261", "end_pos": "1261" }, { "start_pos": "147", "end_pos": "147" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "54", "end_pos": "54" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1385", "end_pos": "1385" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "904", "end_pos": "904" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22219-1.54.54", "start_pos": 54, "end_pos": 54, "uniprot_canonical_ac": "P22219-1", "length": 1454, "uniprot_id": "VPS15_YEAST", "protein_name": "Serine/threonine-protein kinase VPS15", "refseq_ac": "NP_009655", "refseq_name": "ubiquitin-binding serine/threonine protein kinase VPS15", "gene_name": "VPS15", "gene_names_uniprotkb": "VPS15; GRD8; VAC4; VPL19; YBR0825", "gene_names_refseq": "GRD8; VAC4; VPL19; VPS15; VPS40; VPT15", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A genetic and structural analysis of the yeast Vps15 protein kinase: evidence for a direct role of Vps15p in vacuolar protein delivery.", "journal": "The EMBO journal", "date": "1991-12", "authors": "Herman P K, Stack J H, Emr S D", "evidence": [ { "database": "UniProtKB", "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219" } ], "reference": [ { "type": "PubMed", "id": "1756716", "url": "https://glygen.org/publication/PubMed/1756716" } ] } ], "crossref": [ { "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "1756716", "url": "https://glygen.org/publication/PubMed/1756716", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "NSSRFLKTCKALDPNGEIVI", "down_seq": "VFIKPKDQYSLRPFLQRIRA", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "D", "comment": "Loss of activity.", "evidence": [ { "database": "UniProtKB", "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219" }, { "database": "PubMed", "id": "1756716", "url": "https://glygen.org/publication/PubMed/1756716" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1261", "end_pos": "1261" }, { "start_pos": "147", "end_pos": "147" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "54", "end_pos": "54" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1385", "end_pos": "1385" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "904", "end_pos": "904" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22219-1.1003.1003", "start_pos": 1003, "end_pos": 1003, "uniprot_canonical_ac": "P22219-1", "length": 1454, "uniprot_id": "VPS15_YEAST", "protein_name": "Serine/threonine-protein kinase VPS15", "refseq_ac": "NP_009655", "refseq_name": "ubiquitin-binding serine/threonine protein kinase VPS15", "gene_name": "VPS15", "gene_names_uniprotkb": "VPS15; GRD8; VAC4; VPL19; YBR0825", "gene_names_refseq": "GRD8; VAC4; VPL19; VPS15; VPS40; VPT15", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22219" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000301", "url": "https://www.yeastgenome.org/locus/S000000301", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22219", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TTSNLKNVFVQLEPTSYHMH", "down_seq": "PNHGLKDNANVKPERKVVVS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000301", "url": "https://www.yeastgenome.org/locus/S000000301" }, { "database": "iPTMnet", "id": "P22219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22219" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1003" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1261", "end_pos": "1261" }, { "start_pos": "147", "end_pos": "147" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "54", "end_pos": "54" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1385", "end_pos": "1385" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "904", "end_pos": "904" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22219-1.1385.1385", "start_pos": 1385, "end_pos": 1385, "uniprot_canonical_ac": "P22219-1", "length": 1454, "uniprot_id": "VPS15_YEAST", "protein_name": "Serine/threonine-protein kinase VPS15", "refseq_ac": "NP_009655", "refseq_name": "ubiquitin-binding serine/threonine protein kinase VPS15", "gene_name": "VPS15", "gene_names_uniprotkb": "VPS15; GRD8; VAC4; VPL19; YBR0825", "gene_names_refseq": "GRD8; VAC4; VPL19; VPS15; VPS40; VPT15", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P22219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22219" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ], "crossref": [ { "id": "P22219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22219", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ATSSIVMFSLNELSSSKAVI", "down_seq": "PSRFSDVFIPTQVTANLTML", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22219" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ], "site_lbl": "Ser1385" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1261", "end_pos": "1261" }, { "start_pos": "147", "end_pos": "147" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "54", "end_pos": "54" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1385", "end_pos": "1385" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "904", "end_pos": "904" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22219-1.826.826", "start_pos": 826, "end_pos": 826, "uniprot_canonical_ac": "P22219-1", "length": 1454, "uniprot_id": "VPS15_YEAST", "protein_name": "Serine/threonine-protein kinase VPS15", "refseq_ac": "NP_009655", "refseq_name": "ubiquitin-binding serine/threonine protein kinase VPS15", "gene_name": "VPS15", "gene_names_uniprotkb": "VPS15; GRD8; VAC4; VPL19; YBR0825", "gene_names_refseq": "GRD8; VAC4; VPL19; VPS15; VPS40; VPT15", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22219" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000301", "url": "https://www.yeastgenome.org/locus/S000000301", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22219", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TKNYSSKNYGFNKRDTKSSS", "down_seq": "LKGIKTSSTVYSHDNKEIPL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000301", "url": "https://www.yeastgenome.org/locus/S000000301" }, { "database": "iPTMnet", "id": "P22219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22219" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser826" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1261", "end_pos": "1261" }, { "start_pos": "147", "end_pos": "147" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "54", "end_pos": "54" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1385", "end_pos": "1385" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "904", "end_pos": "904" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22219-1.904.904", "start_pos": 904, "end_pos": 904, "uniprot_canonical_ac": "P22219-1", "length": 1454, "uniprot_id": "VPS15_YEAST", "protein_name": "Serine/threonine-protein kinase VPS15", "refseq_ac": "NP_009655", "refseq_name": "ubiquitin-binding serine/threonine protein kinase VPS15", "gene_name": "VPS15", "gene_names_uniprotkb": "VPS15; GRD8; VAC4; VPL19; YBR0825", "gene_names_refseq": "GRD8; VAC4; VPL19; VPS15; VPS40; VPT15", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22219", "url": "https://www.uniprot.org/uniprotkb/P22219" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "iPTMnet", "id": "P22219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22219" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22219" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22219", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000301", "url": "https://www.yeastgenome.org/locus/S000000301", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MAANPDFPYNNSNYRPLVQN", "down_seq": "PPNLNLTNIMPRNIFFDVEF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22219", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22219" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000301", "url": "https://www.yeastgenome.org/locus/S000000301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser904" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "1261", "end_pos": "1261" }, { "start_pos": "147", "end_pos": "147" }, { "start_pos": "149", "end_pos": "149" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "54", "end_pos": "54" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1385", "end_pos": "1385" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "904", "end_pos": "904" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22543-1.442.442", "start_pos": 442, "end_pos": 442, "uniprot_canonical_ac": "P22543-1", "length": 875, "uniprot_id": "VPS34_YEAST", "protein_name": "Phosphatidylinositol 3-kinase VPS34", "refseq_ac": "NP_013341", "refseq_name": "phosphatidylinositol 3-kinase VPS34", "gene_name": "VPS34", "gene_names_uniprotkb": "VPS34; END12; L9672.10; PEP15; VPL7; VPT29", "gene_names_refseq": "END12; PEP15; STT8; VPL7; VPS34; VPS7; VPT29", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22543", "url": "https://www.uniprot.org/uniprotkb/P22543" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P22543", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P22543" }, { "database": "O-GlcNAc Atlas", "id": "P22543", "url": "https://oglcnac.org/atlas/detail/P22543" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22543", "url": "https://oglcnac.org/atlas/detail/P22543", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FSDKSNSEFTIVDAVSSQKL", "down_seq": "GDSMLLSTSHANQKLLKSIS", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser442", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P22543", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P22543" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "442", "end_pos": "442" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "451", "end_pos": "451" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "731", "end_pos": "731" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "749", "end_pos": "749" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "428", "end_pos": "428" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "605", "end_pos": "605" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "P22543-1.428.428", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P22543-1.445.445", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P22543-1.449.449", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P22543-1.451.451", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22543-1.445.445", "start_pos": 445, "end_pos": 445, "uniprot_canonical_ac": "P22543-1", "length": 875, "uniprot_id": "VPS34_YEAST", "protein_name": "Phosphatidylinositol 3-kinase VPS34", "refseq_ac": "NP_013341", "refseq_name": "phosphatidylinositol 3-kinase VPS34", "gene_name": "VPS34", "gene_names_uniprotkb": "VPS34; END12; L9672.10; PEP15; VPL7; VPT29", "gene_names_refseq": "END12; PEP15; STT8; VPL7; VPS34; VPS7; VPT29", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22543", "url": "https://www.uniprot.org/uniprotkb/P22543" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P22543", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P22543" }, { "database": "O-GlcNAc Atlas", "id": "P22543", "url": "https://oglcnac.org/atlas/detail/P22543" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] }, { "title": "Phosphoproteomic responses of TORC1 target kinases reveal discrete and convergent mechanisms that orchestrate the quiescence program in yeast.", "journal": "Cell reports", "date": "2021-12-28", "authors": "Dokl\u00e1dal Ladislav, Stumpe Michael, Hu Zehan, Jaquenoud Malika, Dengjel J\u00f6rn, De Virgilio Claudio", "evidence": [ { "database": "iPTMnet", "id": "P22543", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22543" } ], "reference": [ { "type": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22543", "url": "https://oglcnac.org/atlas/detail/P22543", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "S000004230", "url": "https://www.yeastgenome.org/locus/S000004230", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22543", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22543", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KSNSEFTIVDAVSSQKLSGD", "down_seq": "MLLSTSHANQKLLKSISSES", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser445", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P22543", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P22543" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004230", "url": "https://www.yeastgenome.org/locus/S000004230" }, { "database": "iPTMnet", "id": "P22543", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22543" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ], "site_lbl": "Ser445" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "442", "end_pos": "442" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "451", "end_pos": "451" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "731", "end_pos": "731" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "749", "end_pos": "749" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "428", "end_pos": "428" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "605", "end_pos": "605" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P22543-1.428.428", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P22543-1.442.442", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P22543-1.449.449", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P22543-1.451.451", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22543-1.449.449", "start_pos": 449, "end_pos": 449, "uniprot_canonical_ac": "P22543-1", "length": 875, "uniprot_id": "VPS34_YEAST", "protein_name": "Phosphatidylinositol 3-kinase VPS34", "refseq_ac": "NP_013341", "refseq_name": "phosphatidylinositol 3-kinase VPS34", "gene_name": "VPS34", "gene_names_uniprotkb": "VPS34; END12; L9672.10; PEP15; VPL7; VPT29", "gene_names_refseq": "END12; PEP15; STT8; VPL7; VPS34; VPS7; VPT29", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22543", "url": "https://www.uniprot.org/uniprotkb/P22543" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P22543", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P22543" }, { "database": "O-GlcNAc Atlas", "id": "P22543", "url": "https://oglcnac.org/atlas/detail/P22543" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] }, { "title": "Phosphoproteomic responses of TORC1 target kinases reveal discrete and convergent mechanisms that orchestrate the quiescence program in yeast.", "journal": "Cell reports", "date": "2021-12-28", "authors": "Dokl\u00e1dal Ladislav, Stumpe Michael, Hu Zehan, Jaquenoud Malika, Dengjel J\u00f6rn, De Virgilio Claudio", "evidence": [ { "database": "iPTMnet", "id": "P22543", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22543" } ], "reference": [ { "type": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22543", "url": "https://oglcnac.org/atlas/detail/P22543", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "S000004230", "url": "https://www.yeastgenome.org/locus/S000004230", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22543", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22543", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EFTIVDAVSSQKLSGDSMLL", "down_seq": "TSHANQKLLKSISSESETSG", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser449", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P22543", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P22543" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004230", "url": "https://www.yeastgenome.org/locus/S000004230" }, { "database": "iPTMnet", "id": "P22543", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22543" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ], "site_lbl": "Ser449" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "442", "end_pos": "442" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "451", "end_pos": "451" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "731", "end_pos": "731" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "749", "end_pos": "749" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "428", "end_pos": "428" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "605", "end_pos": "605" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P22543-1.442.442", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P22543-1.445.445", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P22543-1.451.451", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22543-1.451.451", "start_pos": 451, "end_pos": 451, "uniprot_canonical_ac": "P22543-1", "length": 875, "uniprot_id": "VPS34_YEAST", "protein_name": "Phosphatidylinositol 3-kinase VPS34", "refseq_ac": "NP_013341", "refseq_name": "phosphatidylinositol 3-kinase VPS34", "gene_name": "VPS34", "gene_names_uniprotkb": "VPS34; END12; L9672.10; PEP15; VPL7; VPT29", "gene_names_refseq": "END12; PEP15; STT8; VPL7; VPS34; VPS7; VPT29", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22543", "url": "https://www.uniprot.org/uniprotkb/P22543" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P22543", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P22543" }, { "database": "O-GlcNAc Atlas", "id": "P22543", "url": "https://oglcnac.org/atlas/detail/P22543" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P22543", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22543" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22543", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22543" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22543", "url": "https://oglcnac.org/atlas/detail/P22543", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "S000004230", "url": "https://www.yeastgenome.org/locus/S000004230", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22543", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22543", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TIVDAVSSQKLSGDSMLLST", "down_seq": "HANQKLLKSISSESETSGTE", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser451", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P22543", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P22543" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004230", "url": "https://www.yeastgenome.org/locus/S000004230" }, { "database": "iPTMnet", "id": "P22543", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22543" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser451" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "442", "end_pos": "442" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "451", "end_pos": "451" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "731", "end_pos": "731" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "749", "end_pos": "749" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "428", "end_pos": "428" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "605", "end_pos": "605" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "P22543-1.442.442", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P22543-1.445.445", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P22543-1.449.449", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22543-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "P22543-1", "length": 875, "uniprot_id": "VPS34_YEAST", "protein_name": "Phosphatidylinositol 3-kinase VPS34", "refseq_ac": "NP_013341", "refseq_name": "phosphatidylinositol 3-kinase VPS34", "gene_name": "VPS34", "gene_names_uniprotkb": "VPS34; END12; L9672.10; PEP15; VPL7; VPT29", "gene_names_refseq": "END12; PEP15; STT8; VPL7; VPS34; VPS7; VPT29", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22543", "url": "https://www.uniprot.org/uniprotkb/P22543" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P22543", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P22543" }, { "database": "O-GlcNAc Atlas", "id": "P22543", "url": "https://oglcnac.org/atlas/detail/P22543" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22543", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P22543", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P22543", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P22543" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "442", "end_pos": "442" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "451", "end_pos": "451" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "731", "end_pos": "731" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "749", "end_pos": "749" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "428", "end_pos": "428" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "605", "end_pos": "605" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22543-1.731.731", "start_pos": 731, "end_pos": 731, "uniprot_canonical_ac": "P22543-1", "length": 875, "uniprot_id": "VPS34_YEAST", "protein_name": "Phosphatidylinositol 3-kinase VPS34", "refseq_ac": "NP_013341", "refseq_name": "phosphatidylinositol 3-kinase VPS34", "gene_name": "VPS34", "gene_names_uniprotkb": "VPS34; END12; L9672.10; PEP15; VPL7; VPT29", "gene_names_refseq": "END12; PEP15; STT8; VPL7; VPS34; VPS7; VPT29", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22543", "url": "https://www.uniprot.org/uniprotkb/P22543" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting.", "journal": "Science (New York, N.Y.)", "date": "1993-04-02", "authors": "Schu P V, Takegawa K, Fry M J, Stack J H, Waterfield M D, Emr S D", "evidence": [ { "database": "UniProtKB", "id": "P22543", "url": "https://www.uniprot.org/uniprotkb/P22543" } ], "reference": [ { "type": "PubMed", "id": "8385367", "url": "https://glygen.org/publication/PubMed/8385367" } ] } ], "crossref": [ { "id": "P22543", "url": "https://www.uniprot.org/uniprotkb/P22543", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "8385367", "url": "https://glygen.org/publication/PubMed/8385367", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "DNFVKSCAGYCVITYILGVG", "down_seq": "RHLDNLLVTPDGHFFHADFG", "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Loss of kinase activity and no vacuolar carboxypeptidase Y (PCR1) sorting to the vacuole.", "evidence": [ { "database": "UniProtKB", "id": "P22543", "url": "https://www.uniprot.org/uniprotkb/P22543" }, { "database": "PubMed", "id": "8385367", "url": "https://glygen.org/publication/PubMed/8385367" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "442", "end_pos": "442" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "451", "end_pos": "451" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "731", "end_pos": "731" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "749", "end_pos": "749" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "428", "end_pos": "428" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "605", "end_pos": "605" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "upstream", "id": "P22543-1.736.736", "categories": [ "mutagenesis_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P22543-1.749.749", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22543-1.736.736", "start_pos": 736, "end_pos": 736, "uniprot_canonical_ac": "P22543-1", "length": 875, "uniprot_id": "VPS34_YEAST", "protein_name": "Phosphatidylinositol 3-kinase VPS34", "refseq_ac": "NP_013341", "refseq_name": "phosphatidylinositol 3-kinase VPS34", "gene_name": "VPS34", "gene_names_uniprotkb": "VPS34; END12; L9672.10; PEP15; VPL7; VPT29", "gene_names_refseq": "END12; PEP15; STT8; VPL7; VPS34; VPS7; VPT29", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22543", "url": "https://www.uniprot.org/uniprotkb/P22543" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting.", "journal": "Science (New York, N.Y.)", "date": "1993-04-02", "authors": "Schu P V, Takegawa K, Fry M J, Stack J H, Waterfield M D, Emr S D", "evidence": [ { "database": "UniProtKB", "id": "P22543", "url": "https://www.uniprot.org/uniprotkb/P22543" } ], "reference": [ { "type": "PubMed", "id": "8385367", "url": "https://glygen.org/publication/PubMed/8385367" } ] } ], "crossref": [ { "id": "P22543", "url": "https://www.uniprot.org/uniprotkb/P22543", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "8385367", "url": "https://glygen.org/publication/PubMed/8385367", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "SCAGYCVITYILGVGDRHLD", "down_seq": "LLVTPDGHFFHADFGYILGQ", "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "K", "comment": "Loss of kinase activity and no vacuolar carboxypeptidase Y (PCR1) sorting to the vacuole.", "evidence": [ { "database": "UniProtKB", "id": "P22543", "url": "https://www.uniprot.org/uniprotkb/P22543" }, { "database": "PubMed", "id": "8385367", "url": "https://glygen.org/publication/PubMed/8385367" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "442", "end_pos": "442" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "451", "end_pos": "451" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "731", "end_pos": "731" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "749", "end_pos": "749" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "428", "end_pos": "428" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "605", "end_pos": "605" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "P22543-1.731.731", "categories": [ "mutagenesis_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P22543-1.749.749", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22543-1.749.749", "start_pos": 749, "end_pos": 749, "uniprot_canonical_ac": "P22543-1", "length": 875, "uniprot_id": "VPS34_YEAST", "protein_name": "Phosphatidylinositol 3-kinase VPS34", "refseq_ac": "NP_013341", "refseq_name": "phosphatidylinositol 3-kinase VPS34", "gene_name": "VPS34", "gene_names_uniprotkb": "VPS34; END12; L9672.10; PEP15; VPL7; VPT29", "gene_names_refseq": "END12; PEP15; STT8; VPL7; VPS34; VPS7; VPT29", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22543", "url": "https://www.uniprot.org/uniprotkb/P22543" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting.", "journal": "Science (New York, N.Y.)", "date": "1993-04-02", "authors": "Schu P V, Takegawa K, Fry M J, Stack J H, Waterfield M D, Emr S D", "evidence": [ { "database": "UniProtKB", "id": "P22543", "url": "https://www.uniprot.org/uniprotkb/P22543" } ], "reference": [ { "type": "PubMed", "id": "8385367", "url": "https://glygen.org/publication/PubMed/8385367" } ] } ], "crossref": [ { "id": "P22543", "url": "https://www.uniprot.org/uniprotkb/P22543", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "8385367", "url": "https://glygen.org/publication/PubMed/8385367", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "VGDRHLDNLLVTPDGHFFHA", "down_seq": "FGYILGQDPKPFPPLMKLPP", "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "E", "comment": "Loss of kinase activity and no vacuolar carboxypeptidase Y (PCR1) sorting to the vacuole.", "evidence": [ { "database": "UniProtKB", "id": "P22543", "url": "https://www.uniprot.org/uniprotkb/P22543" }, { "database": "PubMed", "id": "8385367", "url": "https://glygen.org/publication/PubMed/8385367" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "442", "end_pos": "442" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "451", "end_pos": "451" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "731", "end_pos": "731" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "749", "end_pos": "749" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "428", "end_pos": "428" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "605", "end_pos": "605" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P22543-1.731.731", "categories": [ "mutagenesis_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P22543-1.736.736", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22543-1.114.114", "start_pos": 114, "end_pos": 114, "uniprot_canonical_ac": "P22543-1", "length": 875, "uniprot_id": "VPS34_YEAST", "protein_name": "Phosphatidylinositol 3-kinase VPS34", "refseq_ac": "NP_013341", "refseq_name": "phosphatidylinositol 3-kinase VPS34", "gene_name": "VPS34", "gene_names_uniprotkb": "VPS34; END12; L9672.10; PEP15; VPL7; VPT29", "gene_names_refseq": "END12; PEP15; STT8; VPL7; VPS34; VPS7; VPT29", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22543", "url": "https://www.uniprot.org/uniprotkb/P22543" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.", "journal": "Genes & development", "date": "2009-08-15", "authors": "Huber Alexandre, Bodenmiller Bernd, Uotila Aino, Stahl Michael, Wanka Stefanie, Gerrits Bertran, Aebersold Ruedi, Loewith Robbie", "evidence": [ { "database": "iPTMnet", "id": "P22543", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22543" } ], "reference": [ { "type": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] } ], "crossref": [ { "id": "P22543", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22543", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "LPIRIKQLTFSSHLRIILWE", "down_seq": "NGSKQIPFFNLETSIFNLKD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22543", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22543" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ], "site_lbl": "Tyr114" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "442", "end_pos": "442" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "451", "end_pos": "451" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "731", "end_pos": "731" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "749", "end_pos": "749" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "428", "end_pos": "428" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "605", "end_pos": "605" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "P22543-1.117.117", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22543-1.117.117", "start_pos": 117, "end_pos": 117, "uniprot_canonical_ac": "P22543-1", "length": 875, "uniprot_id": "VPS34_YEAST", "protein_name": "Phosphatidylinositol 3-kinase VPS34", "refseq_ac": "NP_013341", "refseq_name": "phosphatidylinositol 3-kinase VPS34", "gene_name": "VPS34", "gene_names_uniprotkb": "VPS34; END12; L9672.10; PEP15; VPL7; VPT29", "gene_names_refseq": "END12; PEP15; STT8; VPL7; VPS34; VPS7; VPT29", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22543", "url": "https://www.uniprot.org/uniprotkb/P22543" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.", "journal": "Genes & development", "date": "2009-08-15", "authors": "Huber Alexandre, Bodenmiller Bernd, Uotila Aino, Stahl Michael, Wanka Stefanie, Gerrits Bertran, Aebersold Ruedi, Loewith Robbie", "evidence": [ { "database": "iPTMnet", "id": "P22543", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22543" } ], "reference": [ { "type": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] } ], "crossref": [ { "id": "P22543", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22543", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RIKQLTFSSHLRIILWEYNG", "down_seq": "KQIPFFNLETSIFNLKDCTL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22543", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22543" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ], "site_lbl": "Ser117" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "442", "end_pos": "442" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "451", "end_pos": "451" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "731", "end_pos": "731" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "749", "end_pos": "749" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "428", "end_pos": "428" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "605", "end_pos": "605" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P22543-1.114.114", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22543-1.428.428", "start_pos": 428, "end_pos": 428, "uniprot_canonical_ac": "P22543-1", "length": 875, "uniprot_id": "VPS34_YEAST", "protein_name": "Phosphatidylinositol 3-kinase VPS34", "refseq_ac": "NP_013341", "refseq_name": "phosphatidylinositol 3-kinase VPS34", "gene_name": "VPS34", "gene_names_uniprotkb": "VPS34; END12; L9672.10; PEP15; VPL7; VPT29", "gene_names_refseq": "END12; PEP15; STT8; VPL7; VPS34; VPS7; VPT29", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22543", "url": "https://www.uniprot.org/uniprotkb/P22543" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22543", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22543" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004230", "url": "https://www.yeastgenome.org/locus/S000004230", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22543", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22543", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LQLVEAVCFENLSTFSDKSN", "down_seq": "EFTIVDAVSSQKLSGDSMLL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004230", "url": "https://www.yeastgenome.org/locus/S000004230" }, { "database": "iPTMnet", "id": "P22543", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22543" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser428" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "442", "end_pos": "442" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "451", "end_pos": "451" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "731", "end_pos": "731" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "749", "end_pos": "749" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "428", "end_pos": "428" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "605", "end_pos": "605" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "upstream", "id": "P22543-1.442.442", "categories": [ "glycosylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P22543-1.445.445", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22543-1.605.605", "start_pos": 605, "end_pos": 605, "uniprot_canonical_ac": "P22543-1", "length": 875, "uniprot_id": "VPS34_YEAST", "protein_name": "Phosphatidylinositol 3-kinase VPS34", "refseq_ac": "NP_013341", "refseq_name": "phosphatidylinositol 3-kinase VPS34", "gene_name": "VPS34", "gene_names_uniprotkb": "VPS34; END12; L9672.10; PEP15; VPL7; VPT29", "gene_names_refseq": "END12; PEP15; STT8; VPL7; VPS34; VPS7; VPT29", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22543", "url": "https://www.uniprot.org/uniprotkb/P22543" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22543", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22543" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004230", "url": "https://www.yeastgenome.org/locus/S000004230", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22543", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22543", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PDVLICDVCPETSKVFKSSL", "down_seq": "PLKITFKTTLNQPYHLMFKV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004230", "url": "https://www.yeastgenome.org/locus/S000004230" }, { "database": "iPTMnet", "id": "P22543", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22543" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser605" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "442", "end_pos": "442" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "451", "end_pos": "451" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "731", "end_pos": "731" }, { "start_pos": "736", "end_pos": "736" }, { "start_pos": "749", "end_pos": "749" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "428", "end_pos": "428" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "449", "end_pos": "449" }, { "start_pos": "451", "end_pos": "451" }, { "start_pos": "605", "end_pos": "605" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22696-1.120.120", "start_pos": 120, "end_pos": 120, "uniprot_canonical_ac": "P22696-1", "length": 170, "uniprot_id": "ESS1_YEAST", "protein_name": "Peptidyl-prolyl cis-trans isomerase ESS1", "refseq_ac": "NP_012551", "refseq_name": "peptidylprolyl isomerase ESS1", "gene_name": "ESS1", "gene_names_uniprotkb": "ESS1; J1452; PIN1; PTF1", "gene_names_refseq": "ESS1; PIN1; PTF1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22696", "url": "https://www.uniprot.org/uniprotkb/P22696" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Vanishingly low levels of Ess1 prolyl-isomerase activity are sufficient for growth in Saccharomyces cerevisiae.", "journal": "The Journal of biological chemistry", "date": "2005-04-22", "authors": "Gemmill Trent R, Wu Xiaoyun, Hanes Steven D", "evidence": [ { "database": "UniProtKB", "id": "P22696", "url": "https://www.uniprot.org/uniprotkb/P22696" } ], "reference": [ { "type": "PubMed", "id": "15728580", "url": "https://glygen.org/publication/PubMed/15728580" } ] } ], "crossref": [ { "id": "P22696", "url": "https://www.uniprot.org/uniprotkb/P22696", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "15728580", "url": "https://glygen.org/publication/PubMed/15728580", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "RLDDDSKTNSFEALAKERSD", "down_seq": "SSYKRGGDLGWFGRGEMQPS", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "R", "comment": "Abolishes PPIase activity.", "evidence": [ { "database": "UniProtKB", "id": "P22696", "url": "https://www.uniprot.org/uniprotkb/P22696" }, { "database": "PubMed", "id": "15728580", "url": "https://glygen.org/publication/PubMed/15728580" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "120", "end_pos": "120" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "164", "end_pos": "164" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "109", "end_pos": "109" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "7", "end_pos": "7" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P22696-1.105.105", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P22696-1.107.107", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P22696-1.109.109", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P22696-1.122.122", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P22696-1.127.127", "categories": [ "mutagenesis_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P22696-1.140.140", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22696-1.122.122", "start_pos": 122, "end_pos": 122, "uniprot_canonical_ac": "P22696-1", "length": 170, "uniprot_id": "ESS1_YEAST", "protein_name": "Peptidyl-prolyl cis-trans isomerase ESS1", "refseq_ac": "NP_012551", "refseq_name": "peptidylprolyl isomerase ESS1", "gene_name": "ESS1", "gene_names_uniprotkb": "ESS1; J1452; PIN1; PTF1", "gene_names_refseq": "ESS1; PIN1; PTF1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22696", "url": "https://www.uniprot.org/uniprotkb/P22696" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Vanishingly low levels of Ess1 prolyl-isomerase activity are sufficient for growth in Saccharomyces cerevisiae.", "journal": "The Journal of biological chemistry", "date": "2005-04-22", "authors": "Gemmill Trent R, Wu Xiaoyun, Hanes Steven D", "evidence": [ { "database": "UniProtKB", "id": "P22696", "url": "https://www.uniprot.org/uniprotkb/P22696" } ], "reference": [ { "type": "PubMed", "id": "15728580", "url": "https://glygen.org/publication/PubMed/15728580" } ] } ], "crossref": [ { "id": "P22696", "url": "https://www.uniprot.org/uniprotkb/P22696", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "15728580", "url": "https://glygen.org/publication/PubMed/15728580", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DDDSKTNSFEALAKERSDCS", "down_seq": "YKRGGDLGWFGRGEMQPSFE", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "P", "comment": "Abolishes PPIase activity.", "evidence": [ { "database": "UniProtKB", "id": "P22696", "url": "https://www.uniprot.org/uniprotkb/P22696" }, { "database": "PubMed", "id": "15728580", "url": "https://glygen.org/publication/PubMed/15728580" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "120", "end_pos": "120" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "164", "end_pos": "164" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "109", "end_pos": "109" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "7", "end_pos": "7" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P22696-1.105.105", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P22696-1.107.107", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P22696-1.109.109", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P22696-1.120.120", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P22696-1.127.127", "categories": [ "mutagenesis_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P22696-1.140.140", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22696-1.127.127", "start_pos": 127, "end_pos": 127, "uniprot_canonical_ac": "P22696-1", "length": 170, "uniprot_id": "ESS1_YEAST", "protein_name": "Peptidyl-prolyl cis-trans isomerase ESS1", "refseq_ac": "NP_012551", "refseq_name": "peptidylprolyl isomerase ESS1", "gene_name": "ESS1", "gene_names_uniprotkb": "ESS1; J1452; PIN1; PTF1", "gene_names_refseq": "ESS1; PIN1; PTF1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22696", "url": "https://www.uniprot.org/uniprotkb/P22696" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Mutations in a peptidylprolyl-cis/trans-isomerase gene lead to a defect in 3'-end formation of a pre-mRNA in Saccharomyces cerevisiae.", "journal": "The Journal of biological chemistry", "date": "1999-01-01", "authors": "Hani J, Schelbert B, Bernhardt A, Domdey H, Fischer G, Wiebauer K, Rahfeld J U", "evidence": [ { "database": "UniProtKB", "id": "P22696", "url": "https://www.uniprot.org/uniprotkb/P22696" } ], "reference": [ { "type": "PubMed", "id": "9867817", "url": "https://glygen.org/publication/PubMed/9867817" } ] } ], "crossref": [ { "id": "P22696", "url": "https://www.uniprot.org/uniprotkb/P22696", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "9867817", "url": "https://glygen.org/publication/PubMed/9867817", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "G", "start_aa": "G", "up_seq": "TNSFEALAKERSDCSSYKRG", "down_seq": "DLGWFGRGEMQPSFEDAAFQ", "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "D", "comment": "In PTF1-2; decreases the catalytic efficiency 20-fold.", "evidence": [ { "database": "UniProtKB", "id": "P22696", "url": "https://www.uniprot.org/uniprotkb/P22696" }, { "database": "PubMed", "id": "9867817", "url": "https://glygen.org/publication/PubMed/9867817" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "120", "end_pos": "120" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "164", "end_pos": "164" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "109", "end_pos": "109" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "7", "end_pos": "7" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P22696-1.107.107", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "downstream", "id": "P22696-1.109.109", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P22696-1.120.120", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P22696-1.122.122", "categories": [ "mutagenesis_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P22696-1.140.140", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22696-1.162.162", "start_pos": 162, "end_pos": 162, "uniprot_canonical_ac": "P22696-1", "length": 170, "uniprot_id": "ESS1_YEAST", "protein_name": "Peptidyl-prolyl cis-trans isomerase ESS1", "refseq_ac": "NP_012551", "refseq_name": "peptidylprolyl isomerase ESS1", "gene_name": "ESS1", "gene_names_uniprotkb": "ESS1; J1452; PIN1; PTF1", "gene_names_refseq": "ESS1; PIN1; PTF1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22696", "url": "https://www.uniprot.org/uniprotkb/P22696" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Mutations in a peptidylprolyl-cis/trans-isomerase gene lead to a defect in 3'-end formation of a pre-mRNA in Saccharomyces cerevisiae.", "journal": "The Journal of biological chemistry", "date": "1999-01-01", "authors": "Hani J, Schelbert B, Bernhardt A, Domdey H, Fischer G, Wiebauer K, Rahfeld J U", "evidence": [ { "database": "UniProtKB", "id": "P22696", "url": "https://www.uniprot.org/uniprotkb/P22696" } ], "reference": [ { "type": "PubMed", "id": "9867817", "url": "https://glygen.org/publication/PubMed/9867817" } ] } ], "crossref": [ { "id": "P22696", "url": "https://www.uniprot.org/uniprotkb/P22696", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "9867817", "url": "https://glygen.org/publication/PubMed/9867817", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "G", "start_aa": "G", "up_seq": "EDAAFQLKVGEVSDIVESGS", "down_seq": "VHVIKRVG", "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "S", "comment": "In PTF1-5; decreases the catalytic efficiency 12-fold.", "evidence": [ { "database": "UniProtKB", "id": "P22696", "url": "https://www.uniprot.org/uniprotkb/P22696" }, { "database": "PubMed", "id": "9867817", "url": "https://glygen.org/publication/PubMed/9867817" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "120", "end_pos": "120" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "164", "end_pos": "164" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "109", "end_pos": "109" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "7", "end_pos": "7" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P22696-1.159.159", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P22696-1.161.161", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P22696-1.164.164", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22696-1.164.164", "start_pos": 164, "end_pos": 164, "uniprot_canonical_ac": "P22696-1", "length": 170, "uniprot_id": "ESS1_YEAST", "protein_name": "Peptidyl-prolyl cis-trans isomerase ESS1", "refseq_ac": "NP_012551", "refseq_name": "peptidylprolyl isomerase ESS1", "gene_name": "ESS1", "gene_names_uniprotkb": "ESS1; J1452; PIN1; PTF1", "gene_names_refseq": "ESS1; PIN1; PTF1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22696", "url": "https://www.uniprot.org/uniprotkb/P22696" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Vanishingly low levels of Ess1 prolyl-isomerase activity are sufficient for growth in Saccharomyces cerevisiae.", "journal": "The Journal of biological chemistry", "date": "2005-04-22", "authors": "Gemmill Trent R, Wu Xiaoyun, Hanes Steven D", "evidence": [ { "database": "UniProtKB", "id": "P22696", "url": "https://www.uniprot.org/uniprotkb/P22696" } ], "reference": [ { "type": "PubMed", "id": "15728580", "url": "https://glygen.org/publication/PubMed/15728580" } ] } ], "crossref": [ { "id": "P22696", "url": "https://www.uniprot.org/uniprotkb/P22696", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "15728580", "url": "https://glygen.org/publication/PubMed/15728580", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "H", "start_aa": "H", "up_seq": "AAFQLKVGEVSDIVESGSGV", "down_seq": "VIKRVG", "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "R", "comment": "Abolishes PPIase activity.", "evidence": [ { "database": "UniProtKB", "id": "P22696", "url": "https://www.uniprot.org/uniprotkb/P22696" }, { "database": "PubMed", "id": "15728580", "url": "https://glygen.org/publication/PubMed/15728580" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "120", "end_pos": "120" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "164", "end_pos": "164" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "109", "end_pos": "109" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "7", "end_pos": "7" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "P22696-1.159.159", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P22696-1.161.161", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P22696-1.162.162", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22696-1.105.105", "start_pos": 105, "end_pos": 105, "uniprot_canonical_ac": "P22696-1", "length": 170, "uniprot_id": "ESS1_YEAST", "protein_name": "Peptidyl-prolyl cis-trans isomerase ESS1", "refseq_ac": "NP_012551", "refseq_name": "peptidylprolyl isomerase ESS1", "gene_name": "ESS1", "gene_names_uniprotkb": "ESS1; J1452; PIN1; PTF1", "gene_names_refseq": "ESS1; PIN1; PTF1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22696", "url": "https://www.uniprot.org/uniprotkb/P22696" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22696", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22696" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000003778", "url": "https://www.yeastgenome.org/locus/S000003778", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22696", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22696", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ISKQDATDELKTLITRLDDD", "down_seq": "KTNSFEALAKERSDCSSYKR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003778", "url": "https://www.yeastgenome.org/locus/S000003778" }, { "database": "iPTMnet", "id": "P22696", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22696" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser105" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "120", "end_pos": "120" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "164", "end_pos": "164" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "109", "end_pos": "109" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "7", "end_pos": "7" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P22696-1.107.107", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P22696-1.109.109", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P22696-1.120.120", "categories": [ "mutagenesis_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P22696-1.122.122", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22696-1.107.107", "start_pos": 107, "end_pos": 107, "uniprot_canonical_ac": "P22696-1", "length": 170, "uniprot_id": "ESS1_YEAST", "protein_name": "Peptidyl-prolyl cis-trans isomerase ESS1", "refseq_ac": "NP_012551", "refseq_name": "peptidylprolyl isomerase ESS1", "gene_name": "ESS1", "gene_names_uniprotkb": "ESS1; J1452; PIN1; PTF1", "gene_names_refseq": "ESS1; PIN1; PTF1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22696", "url": "https://www.uniprot.org/uniprotkb/P22696" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22696", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22696" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000003778", "url": "https://www.yeastgenome.org/locus/S000003778", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22696", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22696", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "KQDATDELKTLITRLDDDSK", "down_seq": "NSFEALAKERSDCSSYKRGG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003778", "url": "https://www.yeastgenome.org/locus/S000003778" }, { "database": "iPTMnet", "id": "P22696", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22696" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr107" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "120", "end_pos": "120" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "164", "end_pos": "164" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "109", "end_pos": "109" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "7", "end_pos": "7" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P22696-1.105.105", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P22696-1.109.109", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P22696-1.120.120", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P22696-1.122.122", "categories": [ "mutagenesis_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P22696-1.127.127", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22696-1.109.109", "start_pos": 109, "end_pos": 109, "uniprot_canonical_ac": "P22696-1", "length": 170, "uniprot_id": "ESS1_YEAST", "protein_name": "Peptidyl-prolyl cis-trans isomerase ESS1", "refseq_ac": "NP_012551", "refseq_name": "peptidylprolyl isomerase ESS1", "gene_name": "ESS1", "gene_names_uniprotkb": "ESS1; J1452; PIN1; PTF1", "gene_names_refseq": "ESS1; PIN1; PTF1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22696", "url": "https://www.uniprot.org/uniprotkb/P22696" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P22696", "url": "https://www.uniprot.org/uniprotkb/P22696" }, { "database": "iPTMnet", "id": "P22696", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22696" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Glucose intake hampers PKA-regulated HSP90 chaperone activity.", "journal": "eLife", "date": "2018-12-05", "authors": "Chen Yu-Chen, Jiang Pei-Heng, Chen Hsuan-Ming, Chen Chang-Han, Wang Yi-Ting, Chen Yu-Ju, Yu Chia-Jung, Teng Shu-Chun", "evidence": [ { "database": "iPTMnet", "id": "P22696", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22696" } ], "reference": [ { "type": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22696", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22696" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000003778", "url": "https://www.yeastgenome.org/locus/S000003778", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22696", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22696", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DATDELKTLITRLDDDSKTN", "down_seq": "FEALAKERSDCSSYKRGGDL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003778", "url": "https://www.yeastgenome.org/locus/S000003778" }, { "database": "iPTMnet", "id": "P22696", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22696" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser109" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "120", "end_pos": "120" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "164", "end_pos": "164" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "109", "end_pos": "109" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "7", "end_pos": "7" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P22696-1.105.105", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P22696-1.107.107", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P22696-1.120.120", "categories": [ "mutagenesis_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P22696-1.122.122", "categories": [ "mutagenesis_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P22696-1.127.127", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22696-1.13.13", "start_pos": 13, "end_pos": 13, "uniprot_canonical_ac": "P22696-1", "length": 170, "uniprot_id": "ESS1_YEAST", "protein_name": "Peptidyl-prolyl cis-trans isomerase ESS1", "refseq_ac": "NP_012551", "refseq_name": "peptidylprolyl isomerase ESS1", "gene_name": "ESS1", "gene_names_uniprotkb": "ESS1; J1452; PIN1; PTF1", "gene_names_refseq": "ESS1; PIN1; PTF1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22696", "url": "https://www.uniprot.org/uniprotkb/P22696" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22696", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22696" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000003778", "url": "https://www.yeastgenome.org/locus/S000003778", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22696", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22696", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "MPSDVASRTGLP", "down_seq": "PWTVRYSKSKKREYFFNPET", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003778", "url": "https://www.yeastgenome.org/locus/S000003778" }, { "database": "iPTMnet", "id": "P22696", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22696" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr13" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "120", "end_pos": "120" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "164", "end_pos": "164" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "109", "end_pos": "109" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "7", "end_pos": "7" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "P22696-1.3.3", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P22696-1.7.7", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P22696-1.16.16", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22696-1.140.140", "start_pos": 140, "end_pos": 140, "uniprot_canonical_ac": "P22696-1", "length": 170, "uniprot_id": "ESS1_YEAST", "protein_name": "Peptidyl-prolyl cis-trans isomerase ESS1", "refseq_ac": "NP_012551", "refseq_name": "peptidylprolyl isomerase ESS1", "gene_name": "ESS1", "gene_names_uniprotkb": "ESS1; J1452; PIN1; PTF1", "gene_names_refseq": "ESS1; PIN1; PTF1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22696", "url": "https://www.uniprot.org/uniprotkb/P22696" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P22696", "url": "https://www.uniprot.org/uniprotkb/P22696" }, { "database": "iPTMnet", "id": "P22696", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22696" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22696", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22696" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22696", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22696", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000003778", "url": "https://www.yeastgenome.org/locus/S000003778", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "CSSYKRGGDLGWFGRGEMQP", "down_seq": "FEDAAFQLKVGEVSDIVESG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22696", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22696" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000003778", "url": "https://www.yeastgenome.org/locus/S000003778" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser140" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "120", "end_pos": "120" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "164", "end_pos": "164" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "109", "end_pos": "109" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "7", "end_pos": "7" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P22696-1.120.120", "categories": [ "mutagenesis_flag" ] }, { "distance": 18, "direction": "downstream", "id": "P22696-1.122.122", "categories": [ "mutagenesis_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P22696-1.127.127", "categories": [ "mutagenesis_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P22696-1.159.159", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22696-1.159.159", "start_pos": 159, "end_pos": 159, "uniprot_canonical_ac": "P22696-1", "length": 170, "uniprot_id": "ESS1_YEAST", "protein_name": "Peptidyl-prolyl cis-trans isomerase ESS1", "refseq_ac": "NP_012551", "refseq_name": "peptidylprolyl isomerase ESS1", "gene_name": "ESS1", "gene_names_uniprotkb": "ESS1; J1452; PIN1; PTF1", "gene_names_refseq": "ESS1; PIN1; PTF1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22696", "url": "https://www.uniprot.org/uniprotkb/P22696" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22696", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22696" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000003778", "url": "https://www.yeastgenome.org/locus/S000003778", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22696", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22696", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PSFEDAAFQLKVGEVSDIVE", "down_seq": "GSGVHVIKRVG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003778", "url": "https://www.yeastgenome.org/locus/S000003778" }, { "database": "iPTMnet", "id": "P22696", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22696" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser159" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "120", "end_pos": "120" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "164", "end_pos": "164" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "109", "end_pos": "109" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "7", "end_pos": "7" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P22696-1.140.140", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P22696-1.161.161", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P22696-1.162.162", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P22696-1.164.164", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22696-1.161.161", "start_pos": 161, "end_pos": 161, "uniprot_canonical_ac": "P22696-1", "length": 170, "uniprot_id": "ESS1_YEAST", "protein_name": "Peptidyl-prolyl cis-trans isomerase ESS1", "refseq_ac": "NP_012551", "refseq_name": "peptidylprolyl isomerase ESS1", "gene_name": "ESS1", "gene_names_uniprotkb": "ESS1; J1452; PIN1; PTF1", "gene_names_refseq": "ESS1; PIN1; PTF1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22696", "url": "https://www.uniprot.org/uniprotkb/P22696" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P22696", "url": "https://www.uniprot.org/uniprotkb/P22696" }, { "database": "iPTMnet", "id": "P22696", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22696" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22696", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22696" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P22696", "url": "https://www.uniprot.org/uniprotkb/P22696", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P22696", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22696", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000003778", "url": "https://www.yeastgenome.org/locus/S000003778", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FEDAAFQLKVGEVSDIVESG", "down_seq": "GVHVIKRVG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P22696", "url": "https://www.uniprot.org/uniprotkb/P22696" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P22696", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22696" }, { "database": "SGD", "id": "S000003778", "url": "https://www.yeastgenome.org/locus/S000003778" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser161" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "120", "end_pos": "120" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "164", "end_pos": "164" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "109", "end_pos": "109" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "7", "end_pos": "7" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P22696-1.159.159", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P22696-1.162.162", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P22696-1.164.164", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22696-1.16.16", "start_pos": 16, "end_pos": 16, "uniprot_canonical_ac": "P22696-1", "length": 170, "uniprot_id": "ESS1_YEAST", "protein_name": "Peptidyl-prolyl cis-trans isomerase ESS1", "refseq_ac": "NP_012551", "refseq_name": "peptidylprolyl isomerase ESS1", "gene_name": "ESS1", "gene_names_uniprotkb": "ESS1; J1452; PIN1; PTF1", "gene_names_refseq": "ESS1; PIN1; PTF1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22696", "url": "https://www.uniprot.org/uniprotkb/P22696" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22696", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22696" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000003778", "url": "https://www.yeastgenome.org/locus/S000003778", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22696", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22696", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "MPSDVASRTGLPTPW", "down_seq": "VRYSKSKKREYFFNPETKHS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003778", "url": "https://www.yeastgenome.org/locus/S000003778" }, { "database": "iPTMnet", "id": "P22696", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22696" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr16" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "120", "end_pos": "120" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "164", "end_pos": "164" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "109", "end_pos": "109" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "7", "end_pos": "7" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P22696-1.3.3", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P22696-1.7.7", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P22696-1.13.13", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22696-1.3.3", "start_pos": 3, "end_pos": 3, "uniprot_canonical_ac": "P22696-1", "length": 170, "uniprot_id": "ESS1_YEAST", "protein_name": "Peptidyl-prolyl cis-trans isomerase ESS1", "refseq_ac": "NP_012551", "refseq_name": "peptidylprolyl isomerase ESS1", "gene_name": "ESS1", "gene_names_uniprotkb": "ESS1; J1452; PIN1; PTF1", "gene_names_refseq": "ESS1; PIN1; PTF1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22696", "url": "https://www.uniprot.org/uniprotkb/P22696" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22696", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22696" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000003778", "url": "https://www.yeastgenome.org/locus/S000003778", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22696", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22696", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MP", "down_seq": "DVASRTGLPTPWTVRYSKSK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003778", "url": "https://www.yeastgenome.org/locus/S000003778" }, { "database": "iPTMnet", "id": "P22696", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22696" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser3" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "120", "end_pos": "120" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "164", "end_pos": "164" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "109", "end_pos": "109" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "7", "end_pos": "7" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "P22696-1.7.7", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P22696-1.13.13", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P22696-1.16.16", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P22696-1.7.7", "start_pos": 7, "end_pos": 7, "uniprot_canonical_ac": "P22696-1", "length": 170, "uniprot_id": "ESS1_YEAST", "protein_name": "Peptidyl-prolyl cis-trans isomerase ESS1", "refseq_ac": "NP_012551", "refseq_name": "peptidylprolyl isomerase ESS1", "gene_name": "ESS1", "gene_names_uniprotkb": "ESS1; J1452; PIN1; PTF1", "gene_names_refseq": "ESS1; PIN1; PTF1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P22696", "url": "https://www.uniprot.org/uniprotkb/P22696" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P22696", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22696" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000003778", "url": "https://www.yeastgenome.org/locus/S000003778", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P22696", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22696", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MPSDVA", "down_seq": "RTGLPTPWTVRYSKSKKREY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000003778", "url": "https://www.yeastgenome.org/locus/S000003778" }, { "database": "iPTMnet", "id": "P22696", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22696" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser7" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "120", "end_pos": "120" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "162", "end_pos": "162" }, { "start_pos": "164", "end_pos": "164" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "107", "end_pos": "107" }, { "start_pos": "109", "end_pos": "109" }, { "start_pos": "13", "end_pos": "13" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "161", "end_pos": "161" }, { "start_pos": "16", "end_pos": "16" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "7", "end_pos": "7" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P22696-1.3.3", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P22696-1.13.13", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P22696-1.16.16", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P23287-1.18.18", "start_pos": 18, "end_pos": 18, "uniprot_canonical_ac": "P23287-1", "length": 553, "uniprot_id": "PP2B1_YEAST", "protein_name": "Serine/threonine-protein phosphatase 2B catalytic subunit A1", "refseq_ac": "NP_013537", "refseq_name": "calcineurin catalytic subunit A", "gene_name": "CNA1", "gene_names_uniprotkb": "CNA1; CMP1; L9753.6", "gene_names_refseq": "CMP1; CNA1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P23287", "url": "https://www.uniprot.org/uniprotkb/P23287" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P23287", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23287" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004425", "url": "https://www.yeastgenome.org/locus/S000004425", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P23287", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23287", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MSKDLNSSRIKIIKPND", "down_seq": "YIKVDRKKDLTKYELENGKV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004425", "url": "https://www.yeastgenome.org/locus/S000004425" }, { "database": "iPTMnet", "id": "P23287", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23287" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser18" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "18", "end_pos": "18" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "436", "end_pos": "436" }, { "start_pos": "438", "end_pos": "438" }, { "start_pos": "453", "end_pos": "453" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P23287-1.2.2", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P23287-1.8.8", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P23287-1.280.280", "start_pos": 280, "end_pos": 280, "uniprot_canonical_ac": "P23287-1", "length": 553, "uniprot_id": "PP2B1_YEAST", "protein_name": "Serine/threonine-protein phosphatase 2B catalytic subunit A1", "refseq_ac": "NP_013537", "refseq_name": "calcineurin catalytic subunit A", "gene_name": "CNA1", "gene_names_uniprotkb": "CNA1; CMP1; L9753.6", "gene_names_refseq": "CMP1; CNA1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P23287", "url": "https://www.uniprot.org/uniprotkb/P23287" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P23287", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23287" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P23287", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23287" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P23287", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23287", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004425", "url": "https://www.yeastgenome.org/locus/S000004425", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LWADPVENYDDARDGSEFDQ", "down_seq": "EDEFVPNSLRGCSFAFTFKA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P23287", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23287" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000004425", "url": "https://www.yeastgenome.org/locus/S000004425" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser280" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "18", "end_pos": "18" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "436", "end_pos": "436" }, { "start_pos": "438", "end_pos": "438" }, { "start_pos": "453", "end_pos": "453" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P23287-1.2.2", "start_pos": 2, "end_pos": 2, "uniprot_canonical_ac": "P23287-1", "length": 553, "uniprot_id": "PP2B1_YEAST", "protein_name": "Serine/threonine-protein phosphatase 2B catalytic subunit A1", "refseq_ac": "NP_013537", "refseq_name": "calcineurin catalytic subunit A", "gene_name": "CNA1", "gene_names_uniprotkb": "CNA1; CMP1; L9753.6", "gene_names_refseq": "CMP1; CNA1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P23287", "url": "https://www.uniprot.org/uniprotkb/P23287" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P23287", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23287" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004425", "url": "https://www.yeastgenome.org/locus/S000004425", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P23287", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23287", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "M", "down_seq": "KDLNSSRIKIIKPNDSYIKV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004425", "url": "https://www.yeastgenome.org/locus/S000004425" }, { "database": "iPTMnet", "id": "P23287", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23287" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser2" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "18", "end_pos": "18" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "436", "end_pos": "436" }, { "start_pos": "438", "end_pos": "438" }, { "start_pos": "453", "end_pos": "453" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "upstream", "id": "P23287-1.8.8", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P23287-1.18.18", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P23287-1.436.436", "start_pos": 436, "end_pos": 436, "uniprot_canonical_ac": "P23287-1", "length": 553, "uniprot_id": "PP2B1_YEAST", "protein_name": "Serine/threonine-protein phosphatase 2B catalytic subunit A1", "refseq_ac": "NP_013537", "refseq_name": "calcineurin catalytic subunit A", "gene_name": "CNA1", "gene_names_uniprotkb": "CNA1; CMP1; L9753.6", "gene_names_refseq": "CMP1; CNA1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P23287", "url": "https://www.uniprot.org/uniprotkb/P23287" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P23287", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23287" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004425", "url": "https://www.yeastgenome.org/locus/S000004425", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P23287", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23287", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "ESEPKAAEETVKARANATKE", "down_seq": "GTPSDEKASSAILEDETRRK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004425", "url": "https://www.yeastgenome.org/locus/S000004425" }, { "database": "iPTMnet", "id": "P23287", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23287" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr436" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "18", "end_pos": "18" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "436", "end_pos": "436" }, { "start_pos": "438", "end_pos": "438" }, { "start_pos": "453", "end_pos": "453" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P23287-1.438.438", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P23287-1.453.453", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P23287-1.438.438", "start_pos": 438, "end_pos": 438, "uniprot_canonical_ac": "P23287-1", "length": 553, "uniprot_id": "PP2B1_YEAST", "protein_name": "Serine/threonine-protein phosphatase 2B catalytic subunit A1", "refseq_ac": "NP_013537", "refseq_name": "calcineurin catalytic subunit A", "gene_name": "CNA1", "gene_names_uniprotkb": "CNA1; CMP1; L9753.6", "gene_names_refseq": "CMP1; CNA1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P23287", "url": "https://www.uniprot.org/uniprotkb/P23287" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P23287", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23287" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P23287", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23287" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004425", "url": "https://www.yeastgenome.org/locus/S000004425", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P23287", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23287", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "EPKAAEETVKARANATKETG", "down_seq": "PSDEKASSAILEDETRRKAL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004425", "url": "https://www.yeastgenome.org/locus/S000004425" }, { "database": "iPTMnet", "id": "P23287", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23287" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr438" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "18", "end_pos": "18" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "436", "end_pos": "436" }, { "start_pos": "438", "end_pos": "438" }, { "start_pos": "453", "end_pos": "453" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P23287-1.436.436", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P23287-1.453.453", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P23287-1.453.453", "start_pos": 453, "end_pos": 453, "uniprot_canonical_ac": "P23287-1", "length": 553, "uniprot_id": "PP2B1_YEAST", "protein_name": "Serine/threonine-protein phosphatase 2B catalytic subunit A1", "refseq_ac": "NP_013537", "refseq_name": "calcineurin catalytic subunit A", "gene_name": "CNA1", "gene_names_uniprotkb": "CNA1; CMP1; L9753.6", "gene_names_refseq": "CMP1; CNA1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P23287", "url": "https://www.uniprot.org/uniprotkb/P23287" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P23287", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23287" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004425", "url": "https://www.yeastgenome.org/locus/S000004425", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P23287", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23287", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "TKETGTPSDEKASSAILEDE", "down_seq": "RRKALRNKILAIAKVSRMFS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004425", "url": "https://www.yeastgenome.org/locus/S000004425" }, { "database": "iPTMnet", "id": "P23287", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23287" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr453" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "18", "end_pos": "18" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "436", "end_pos": "436" }, { "start_pos": "438", "end_pos": "438" }, { "start_pos": "453", "end_pos": "453" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P23287-1.436.436", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P23287-1.438.438", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P23287-1.8.8", "start_pos": 8, "end_pos": 8, "uniprot_canonical_ac": "P23287-1", "length": 553, "uniprot_id": "PP2B1_YEAST", "protein_name": "Serine/threonine-protein phosphatase 2B catalytic subunit A1", "refseq_ac": "NP_013537", "refseq_name": "calcineurin catalytic subunit A", "gene_name": "CNA1", "gene_names_uniprotkb": "CNA1; CMP1; L9753.6", "gene_names_refseq": "CMP1; CNA1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P23287", "url": "https://www.uniprot.org/uniprotkb/P23287" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P23287", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23287" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004425", "url": "https://www.yeastgenome.org/locus/S000004425", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P23287", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23287", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MSKDLNS", "down_seq": "RIKIIKPNDSYIKVDRKKDL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004425", "url": "https://www.yeastgenome.org/locus/S000004425" }, { "database": "iPTMnet", "id": "P23287", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23287" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser8" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "18", "end_pos": "18" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "436", "end_pos": "436" }, { "start_pos": "438", "end_pos": "438" }, { "start_pos": "453", "end_pos": "453" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "P23287-1.2.2", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P23287-1.18.18", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P23291-1.415.415", "start_pos": 415, "end_pos": 415, "uniprot_canonical_ac": "P23291-1", "length": 538, "uniprot_id": "KC11_YEAST", "protein_name": "Casein kinase I homolog 1", "refseq_ac": "NP_012003", "refseq_name": "serine/threonine protein kinase YCK1", "gene_name": "YCK1", "gene_names_uniprotkb": "YCK1; CKI2", "gene_names_refseq": "CKI2; YCK1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P23291", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P23291" }, { "database": "O-GlcNAc Atlas", "id": "P23291", "url": "https://oglcnac.org/atlas/detail/P23291" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P23291", "url": "https://oglcnac.org/atlas/detail/P23291", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "QQLQMQQLQQQQQQQQYAQK", "down_seq": "EADMRNSQYKPKLDPTSYEA", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr415", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P23291", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P23291" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "415", "end_pos": "415" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "236", "end_pos": "236" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "422", "end_pos": "422" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "512", "end_pos": "512" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "upstream", "id": "P23291-1.422.422", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P23291-1.43.43", "start_pos": 43, "end_pos": 43, "uniprot_canonical_ac": "P23291-1", "length": 538, "uniprot_id": "KC11_YEAST", "protein_name": "Casein kinase I homolog 1", "refseq_ac": "NP_012003", "refseq_name": "serine/threonine protein kinase YCK1", "gene_name": "YCK1", "gene_names_uniprotkb": "YCK1; CKI2", "gene_names_refseq": "CKI2; YCK1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P23291", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P23291" }, { "database": "O-GlcNAc Atlas", "id": "P23291", "url": "https://oglcnac.org/atlas/detail/P23291" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] }, { "title": "Glucose intake hampers PKA-regulated HSP90 chaperone activity.", "journal": "eLife", "date": "2018-12-05", "authors": "Chen Yu-Chen, Jiang Pei-Heng, Chen Hsuan-Ming, Chen Chang-Han, Wang Yi-Ting, Chen Yu-Ju, Yu Chia-Jung, Teng Shu-Chun", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P23291", "url": "https://oglcnac.org/atlas/detail/P23291", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NFNVQANKQLHHQAVDSPAR", "down_seq": "SMTATTAANSNSNSSRDDST", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser43", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P23291", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P23291" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177" }, { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser43" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "415", "end_pos": "415" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "236", "end_pos": "236" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "422", "end_pos": "422" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "512", "end_pos": "512" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P23291-1.39.39", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P23291-1.44.44", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P23291-1.46.46", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P23291-1.53.53", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P23291-1.55.55", "categories": [ "glycosylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P23291-1.57.57", "categories": [ "glycosylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P23291-1.58.58", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P23291-1.62.62", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P23291-1.63.63", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P23291-1.44.44", "start_pos": 44, "end_pos": 44, "uniprot_canonical_ac": "P23291-1", "length": 538, "uniprot_id": "KC11_YEAST", "protein_name": "Casein kinase I homolog 1", "refseq_ac": "NP_012003", "refseq_name": "serine/threonine protein kinase YCK1", "gene_name": "YCK1", "gene_names_uniprotkb": "YCK1; CKI2", "gene_names_refseq": "CKI2; YCK1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P23291", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P23291" }, { "database": "O-GlcNAc Atlas", "id": "P23291", "url": "https://oglcnac.org/atlas/detail/P23291" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] }, { "title": "Glucose intake hampers PKA-regulated HSP90 chaperone activity.", "journal": "eLife", "date": "2018-12-05", "authors": "Chen Yu-Chen, Jiang Pei-Heng, Chen Hsuan-Ming, Chen Chang-Han, Wang Yi-Ting, Chen Yu-Ju, Yu Chia-Jung, Teng Shu-Chun", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P23291", "url": "https://oglcnac.org/atlas/detail/P23291", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FNVQANKQLHHQAVDSPARS", "down_seq": "MTATTAANSNSNSSRDDSTI", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser44", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P23291", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P23291" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177" }, { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser44" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "415", "end_pos": "415" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "236", "end_pos": "236" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "422", "end_pos": "422" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "512", "end_pos": "512" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "P23291-1.39.39", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P23291-1.43.43", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P23291-1.46.46", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P23291-1.53.53", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P23291-1.55.55", "categories": [ "glycosylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P23291-1.57.57", "categories": [ "glycosylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P23291-1.58.58", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P23291-1.62.62", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P23291-1.63.63", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P23291-1.480.480", "start_pos": 480, "end_pos": 480, "uniprot_canonical_ac": "P23291-1", "length": 538, "uniprot_id": "KC11_YEAST", "protein_name": "Casein kinase I homolog 1", "refseq_ac": "NP_012003", "refseq_name": "serine/threonine protein kinase YCK1", "gene_name": "YCK1", "gene_names_uniprotkb": "YCK1; CKI2", "gene_names_refseq": "CKI2; YCK1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P23291", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P23291" }, { "database": "O-GlcNAc Atlas", "id": "P23291", "url": "https://oglcnac.org/atlas/detail/P23291" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] }, { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P23291", "url": "https://oglcnac.org/atlas/detail/P23291", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "QQLQEQQLQQQQQQQQQLRA", "down_seq": "GQPPSQPQAQTQSQQFGARY", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr480", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P23291", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P23291" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ], "site_lbl": "Thr480" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "415", "end_pos": "415" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "236", "end_pos": "236" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "422", "end_pos": "422" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "512", "end_pos": "512" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "upstream", "id": "P23291-1.485.485", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P23291-1.491.491", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P23291-1.493.493", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P23291-1.485.485", "start_pos": 485, "end_pos": 485, "uniprot_canonical_ac": "P23291-1", "length": 538, "uniprot_id": "KC11_YEAST", "protein_name": "Casein kinase I homolog 1", "refseq_ac": "NP_012003", "refseq_name": "serine/threonine protein kinase YCK1", "gene_name": "YCK1", "gene_names_uniprotkb": "YCK1; CKI2", "gene_names_refseq": "CKI2; YCK1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P23291", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P23291" }, { "database": "O-GlcNAc Atlas", "id": "P23291", "url": "https://oglcnac.org/atlas/detail/P23291" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" }, { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P23291", "url": "https://oglcnac.org/atlas/detail/P23291", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QQLQQQQQQQQQLRATGQPP", "down_seq": "QPQAQTQSQQFGARYQPQQQ", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser485", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P23291", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P23291" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser485" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "415", "end_pos": "415" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "236", "end_pos": "236" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "422", "end_pos": "422" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "512", "end_pos": "512" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "P23291-1.480.480", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P23291-1.491.491", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P23291-1.493.493", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P23291-1.493.493", "start_pos": 493, "end_pos": 493, "uniprot_canonical_ac": "P23291-1", "length": 538, "uniprot_id": "KC11_YEAST", "protein_name": "Casein kinase I homolog 1", "refseq_ac": "NP_012003", "refseq_name": "serine/threonine protein kinase YCK1", "gene_name": "YCK1", "gene_names_uniprotkb": "YCK1; CKI2", "gene_names_refseq": "CKI2; YCK1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P23291", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P23291" }, { "database": "O-GlcNAc Atlas", "id": "P23291", "url": "https://oglcnac.org/atlas/detail/P23291" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" }, { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P23291", "url": "https://oglcnac.org/atlas/detail/P23291", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QQQQLRATGQPPSQPQAQTQ", "down_seq": "QQFGARYQPQQQPSAALRTP", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser493", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P23291", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P23291" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser493" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "415", "end_pos": "415" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "236", "end_pos": "236" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "422", "end_pos": "422" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "512", "end_pos": "512" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P23291-1.480.480", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P23291-1.485.485", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P23291-1.491.491", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P23291-1.507.507", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P23291-1.512.512", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P23291-1.53.53", "start_pos": 53, "end_pos": 53, "uniprot_canonical_ac": "P23291-1", "length": 538, "uniprot_id": "KC11_YEAST", "protein_name": "Casein kinase I homolog 1", "refseq_ac": "NP_012003", "refseq_name": "serine/threonine protein kinase YCK1", "gene_name": "YCK1", "gene_names_uniprotkb": "YCK1; CKI2", "gene_names_refseq": "CKI2; YCK1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P23291", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P23291" }, { "database": "O-GlcNAc Atlas", "id": "P23291", "url": "https://oglcnac.org/atlas/detail/P23291" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] }, { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P23291", "url": "https://oglcnac.org/atlas/detail/P23291", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "HHQAVDSPARSSMTATTAAN", "down_seq": "NSNSSRDDSTIVGLHYKIGK", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser53", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P23291", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P23291" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser53" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "415", "end_pos": "415" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "236", "end_pos": "236" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "422", "end_pos": "422" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "512", "end_pos": "512" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "P23291-1.39.39", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P23291-1.43.43", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P23291-1.44.44", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P23291-1.46.46", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P23291-1.55.55", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P23291-1.57.57", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P23291-1.58.58", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P23291-1.62.62", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P23291-1.63.63", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P23291-1.55.55", "start_pos": 55, "end_pos": 55, "uniprot_canonical_ac": "P23291-1", "length": 538, "uniprot_id": "KC11_YEAST", "protein_name": "Casein kinase I homolog 1", "refseq_ac": "NP_012003", "refseq_name": "serine/threonine protein kinase YCK1", "gene_name": "YCK1", "gene_names_uniprotkb": "YCK1; CKI2", "gene_names_refseq": "CKI2; YCK1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P23291", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P23291" }, { "database": "O-GlcNAc Atlas", "id": "P23291", "url": "https://oglcnac.org/atlas/detail/P23291" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P23291", "url": "https://oglcnac.org/atlas/detail/P23291", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QAVDSPARSSMTATTAANSN", "down_seq": "NSSRDDSTIVGLHYKIGKKI", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser55", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P23291", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P23291" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "415", "end_pos": "415" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "236", "end_pos": "236" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "422", "end_pos": "422" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "512", "end_pos": "512" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P23291-1.39.39", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P23291-1.43.43", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P23291-1.44.44", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P23291-1.46.46", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P23291-1.53.53", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P23291-1.57.57", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P23291-1.58.58", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P23291-1.62.62", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P23291-1.63.63", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P23291-1.57.57", "start_pos": 57, "end_pos": 57, "uniprot_canonical_ac": "P23291-1", "length": 538, "uniprot_id": "KC11_YEAST", "protein_name": "Casein kinase I homolog 1", "refseq_ac": "NP_012003", "refseq_name": "serine/threonine protein kinase YCK1", "gene_name": "YCK1", "gene_names_uniprotkb": "YCK1; CKI2", "gene_names_refseq": "CKI2; YCK1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P23291", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P23291" }, { "database": "O-GlcNAc Atlas", "id": "P23291", "url": "https://oglcnac.org/atlas/detail/P23291" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P23291", "url": "https://oglcnac.org/atlas/detail/P23291", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VDSPARSSMTATTAANSNSN", "down_seq": "SRDDSTIVGLHYKIGKKIGE", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser57", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P23291", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P23291" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "415", "end_pos": "415" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "236", "end_pos": "236" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "422", "end_pos": "422" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "512", "end_pos": "512" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P23291-1.39.39", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P23291-1.43.43", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P23291-1.44.44", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P23291-1.46.46", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P23291-1.53.53", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P23291-1.55.55", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P23291-1.58.58", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P23291-1.62.62", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P23291-1.63.63", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P23291-1.58.58", "start_pos": 58, "end_pos": 58, "uniprot_canonical_ac": "P23291-1", "length": 538, "uniprot_id": "KC11_YEAST", "protein_name": "Casein kinase I homolog 1", "refseq_ac": "NP_012003", "refseq_name": "serine/threonine protein kinase YCK1", "gene_name": "YCK1", "gene_names_uniprotkb": "YCK1; CKI2", "gene_names_refseq": "CKI2; YCK1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P23291", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P23291" }, { "database": "O-GlcNAc Atlas", "id": "P23291", "url": "https://oglcnac.org/atlas/detail/P23291" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P23291", "url": "https://oglcnac.org/atlas/detail/P23291", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DSPARSSMTATTAANSNSNS", "down_seq": "RDDSTIVGLHYKIGKKIGEG", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser58", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P23291", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P23291" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177" }, { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser58" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "415", "end_pos": "415" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "236", "end_pos": "236" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "422", "end_pos": "422" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "512", "end_pos": "512" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P23291-1.39.39", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P23291-1.43.43", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P23291-1.44.44", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P23291-1.46.46", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P23291-1.53.53", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P23291-1.55.55", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P23291-1.57.57", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P23291-1.62.62", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P23291-1.63.63", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P23291-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "P23291-1", "length": 538, "uniprot_id": "KC11_YEAST", "protein_name": "Casein kinase I homolog 1", "refseq_ac": "NP_012003", "refseq_name": "serine/threonine protein kinase YCK1", "gene_name": "YCK1", "gene_names_uniprotkb": "YCK1; CKI2", "gene_names_refseq": "CKI2; YCK1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P23291", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P23291" }, { "database": "O-GlcNAc Atlas", "id": "P23291", "url": "https://oglcnac.org/atlas/detail/P23291" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P23291", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P23291", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P23291", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P23291" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "415", "end_pos": "415" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "236", "end_pos": "236" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "422", "end_pos": "422" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "512", "end_pos": "512" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P23291-1.236.236", "start_pos": 236, "end_pos": 236, "uniprot_canonical_ac": "P23291-1", "length": 538, "uniprot_id": "KC11_YEAST", "protein_name": "Casein kinase I homolog 1", "refseq_ac": "NP_012003", "refseq_name": "serine/threonine protein kinase YCK1", "gene_name": "YCK1", "gene_names_uniprotkb": "YCK1; CKI2", "gene_names_refseq": "CKI2; YCK1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ], "crossref": [ { "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KQYRDPKTKQHIPYREKKSL", "down_seq": "GTARYMSINTHLGREQSRRD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177" }, { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ], "site_lbl": "Ser236" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "415", "end_pos": "415" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "236", "end_pos": "236" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "422", "end_pos": "422" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "512", "end_pos": "512" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P23291-1.238.238", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P23291-1.238.238", "start_pos": 238, "end_pos": 238, "uniprot_canonical_ac": "P23291-1", "length": 538, "uniprot_id": "KC11_YEAST", "protein_name": "Casein kinase I homolog 1", "refseq_ac": "NP_012003", "refseq_name": "serine/threonine protein kinase YCK1", "gene_name": "YCK1", "gene_names_uniprotkb": "YCK1; CKI2", "gene_names_refseq": "CKI2; YCK1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ], "crossref": [ { "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "YRDPKTKQHIPYREKKSLSG", "down_seq": "ARYMSINTHLGREQSRRDDM", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177" }, { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ], "site_lbl": "Thr238" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "415", "end_pos": "415" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "236", "end_pos": "236" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "422", "end_pos": "422" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "512", "end_pos": "512" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P23291-1.236.236", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P23291-1.39.39", "start_pos": 39, "end_pos": 39, "uniprot_canonical_ac": "P23291-1", "length": 538, "uniprot_id": "KC11_YEAST", "protein_name": "Casein kinase I homolog 1", "refseq_ac": "NP_012003", "refseq_name": "serine/threonine protein kinase YCK1", "gene_name": "YCK1", "gene_names_uniprotkb": "YCK1; CKI2", "gene_names_refseq": "CKI2; YCK1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NGNANFNVQANKQLHHQAVD", "down_seq": "PARSSMTATTAANSNSNSSR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser39" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "415", "end_pos": "415" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "236", "end_pos": "236" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "422", "end_pos": "422" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "512", "end_pos": "512" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "P23291-1.43.43", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P23291-1.44.44", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P23291-1.46.46", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P23291-1.53.53", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P23291-1.55.55", "categories": [ "glycosylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P23291-1.57.57", "categories": [ "glycosylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P23291-1.58.58", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P23291-1.422.422", "start_pos": 422, "end_pos": 422, "uniprot_canonical_ac": "P23291-1", "length": 538, "uniprot_id": "KC11_YEAST", "protein_name": "Casein kinase I homolog 1", "refseq_ac": "NP_012003", "refseq_name": "serine/threonine protein kinase YCK1", "gene_name": "YCK1", "gene_names_uniprotkb": "YCK1; CKI2", "gene_names_refseq": "CKI2; YCK1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LQQQQQQQQYAQKTEADMRN", "down_seq": "QYKPKLDPTSYEAYQHQTQQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177" }, { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser422" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "415", "end_pos": "415" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "236", "end_pos": "236" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "422", "end_pos": "422" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "512", "end_pos": "512" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P23291-1.415.415", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P23291-1.46.46", "start_pos": 46, "end_pos": 46, "uniprot_canonical_ac": "P23291-1", "length": 538, "uniprot_id": "KC11_YEAST", "protein_name": "Casein kinase I homolog 1", "refseq_ac": "NP_012003", "refseq_name": "serine/threonine protein kinase YCK1", "gene_name": "YCK1", "gene_names_uniprotkb": "YCK1; CKI2", "gene_names_refseq": "CKI2; YCK1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "VQANKQLHHQAVDSPARSSM", "down_seq": "ATTAANSNSNSSRDDSTIVG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177" }, { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr46" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "415", "end_pos": "415" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "236", "end_pos": "236" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "422", "end_pos": "422" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "512", "end_pos": "512" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P23291-1.39.39", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P23291-1.43.43", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P23291-1.44.44", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P23291-1.53.53", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P23291-1.55.55", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P23291-1.57.57", "categories": [ "glycosylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P23291-1.58.58", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P23291-1.62.62", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P23291-1.63.63", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P23291-1.491.491", "start_pos": 491, "end_pos": 491, "uniprot_canonical_ac": "P23291-1", "length": 538, "uniprot_id": "KC11_YEAST", "protein_name": "Casein kinase I homolog 1", "refseq_ac": "NP_012003", "refseq_name": "serine/threonine protein kinase YCK1", "gene_name": "YCK1", "gene_names_uniprotkb": "YCK1; CKI2", "gene_names_refseq": "CKI2; YCK1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "QQQQQQLRATGQPPSQPQAQ", "down_seq": "QSQQFGARYQPQQQPSAALR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177" }, { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr491" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "415", "end_pos": "415" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "236", "end_pos": "236" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "422", "end_pos": "422" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "512", "end_pos": "512" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P23291-1.480.480", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P23291-1.485.485", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P23291-1.493.493", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P23291-1.507.507", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P23291-1.507.507", "start_pos": 507, "end_pos": 507, "uniprot_canonical_ac": "P23291-1", "length": 538, "uniprot_id": "KC11_YEAST", "protein_name": "Casein kinase I homolog 1", "refseq_ac": "NP_012003", "refseq_name": "serine/threonine protein kinase YCK1", "gene_name": "YCK1", "gene_names_uniprotkb": "YCK1; CKI2", "gene_names_refseq": "CKI2; YCK1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PQAQTQSQQFGARYQPQQQP", "down_seq": "AALRTPEQHPNDDNSSLAAS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177" }, { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser507" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "415", "end_pos": "415" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "236", "end_pos": "236" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "422", "end_pos": "422" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "512", "end_pos": "512" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P23291-1.491.491", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P23291-1.493.493", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P23291-1.512.512", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P23291-1.522.522", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P23291-1.523.523", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P23291-1.527.527", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P23291-1.512.512", "start_pos": 512, "end_pos": 512, "uniprot_canonical_ac": "P23291-1", "length": 538, "uniprot_id": "KC11_YEAST", "protein_name": "Casein kinase I homolog 1", "refseq_ac": "NP_012003", "refseq_name": "serine/threonine protein kinase YCK1", "gene_name": "YCK1", "gene_names_uniprotkb": "YCK1; CKI2", "gene_names_refseq": "CKI2; YCK1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "QSQQFGARYQPQQQPSAALR", "down_seq": "PEQHPNDDNSSLAASHKGFF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177" }, { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr512" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "415", "end_pos": "415" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "236", "end_pos": "236" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "422", "end_pos": "422" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "512", "end_pos": "512" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P23291-1.493.493", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P23291-1.507.507", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P23291-1.522.522", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P23291-1.523.523", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P23291-1.527.527", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P23291-1.522.522", "start_pos": 522, "end_pos": 522, "uniprot_canonical_ac": "P23291-1", "length": 538, "uniprot_id": "KC11_YEAST", "protein_name": "Casein kinase I homolog 1", "refseq_ac": "NP_012003", "refseq_name": "serine/threonine protein kinase YCK1", "gene_name": "YCK1", "gene_names_uniprotkb": "YCK1; CKI2", "gene_names_refseq": "CKI2; YCK1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "Journal of proteome research", "date": "2007-03", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" }, { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" }, { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Mol. Cell. Proteomics", "date": "2008", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" }, { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.", "journal": "Genes & development", "date": "2009-08-15", "authors": "Huber Alexandre, Bodenmiller Bernd, Uotila Aino, Stahl Michael, Wanka Stefanie, Gerrits Bertran, Aebersold Ruedi, Loewith Robbie", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] }, { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast.", "journal": "Science signaling", "date": "2010-12-21", "authors": "Bodenmiller Bernd, Wanka Stefanie, Kraft Claudine, Urban J\u00f6rg, Campbell David, Pedrioli Patrick G, Gerrits Bertran, Picotti Paola, Lam Henry, Vitek Olga, Brusniak Mi-Youn, Roschitzki Bernd, Zhang Chao, Shokat Kevan M, Schlapbach Ralph, Colman-Lerner Alejandro, Nolan Garry P, Nesvizhskii Alexey I, Peter Matthias, Loewith Robbie, von Mering Christian, Aebersold Ruedi", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PQQQPSAALRTPEQHPNDDN", "down_seq": "SLAASHKGFFQKLGCC", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser522" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "415", "end_pos": "415" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "236", "end_pos": "236" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "422", "end_pos": "422" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "512", "end_pos": "512" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P23291-1.507.507", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P23291-1.512.512", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P23291-1.523.523", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P23291-1.527.527", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P23291-1.523.523", "start_pos": 523, "end_pos": 523, "uniprot_canonical_ac": "P23291-1", "length": 538, "uniprot_id": "KC11_YEAST", "protein_name": "Casein kinase I homolog 1", "refseq_ac": "NP_012003", "refseq_name": "serine/threonine protein kinase YCK1", "gene_name": "YCK1", "gene_names_uniprotkb": "YCK1; CKI2", "gene_names_refseq": "CKI2; YCK1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" }, { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "Journal of proteome research", "date": "2007-03", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" }, { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Mol. Cell. Proteomics", "date": "2008", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" }, { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.", "journal": "Genes & development", "date": "2009-08-15", "authors": "Huber Alexandre, Bodenmiller Bernd, Uotila Aino, Stahl Michael, Wanka Stefanie, Gerrits Bertran, Aebersold Ruedi, Loewith Robbie", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] }, { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast.", "journal": "Science signaling", "date": "2010-12-21", "authors": "Bodenmiller Bernd, Wanka Stefanie, Kraft Claudine, Urban J\u00f6rg, Campbell David, Pedrioli Patrick G, Gerrits Bertran, Picotti Paola, Lam Henry, Vitek Olga, Brusniak Mi-Youn, Roschitzki Bernd, Zhang Chao, Shokat Kevan M, Schlapbach Ralph, Colman-Lerner Alejandro, Nolan Garry P, Nesvizhskii Alexey I, Peter Matthias, Loewith Robbie, von Mering Christian, Aebersold Ruedi", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Glucose intake hampers PKA-regulated HSP90 chaperone activity.", "journal": "eLife", "date": "2018-12-05", "authors": "Chen Yu-Chen, Jiang Pei-Heng, Chen Hsuan-Ming, Chen Chang-Han, Wang Yi-Ting, Chen Yu-Ju, Yu Chia-Jung, Teng Shu-Chun", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QQQPSAALRTPEQHPNDDNS", "down_seq": "LAASHKGFFQKLGCC", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser523" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "415", "end_pos": "415" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "236", "end_pos": "236" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "422", "end_pos": "422" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "512", "end_pos": "512" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P23291-1.507.507", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P23291-1.512.512", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P23291-1.522.522", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P23291-1.527.527", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 12 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P23291-1.527.527", "start_pos": 527, "end_pos": 527, "uniprot_canonical_ac": "P23291-1", "length": 538, "uniprot_id": "KC11_YEAST", "protein_name": "Casein kinase I homolog 1", "refseq_ac": "NP_012003", "refseq_name": "serine/threonine protein kinase YCK1", "gene_name": "YCK1", "gene_names_uniprotkb": "YCK1; CKI2", "gene_names_refseq": "CKI2; YCK1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "Journal of proteome research", "date": "2007-03", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" }, { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" }, { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.", "journal": "Genes & development", "date": "2009-08-15", "authors": "Huber Alexandre, Bodenmiller Bernd, Uotila Aino, Stahl Michael, Wanka Stefanie, Gerrits Bertran, Aebersold Ruedi, Loewith Robbie", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] }, { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast.", "journal": "Science signaling", "date": "2010-12-21", "authors": "Bodenmiller Bernd, Wanka Stefanie, Kraft Claudine, Urban J\u00f6rg, Campbell David, Pedrioli Patrick G, Gerrits Bertran, Picotti Paola, Lam Henry, Vitek Olga, Brusniak Mi-Youn, Roschitzki Bernd, Zhang Chao, Shokat Kevan M, Schlapbach Ralph, Colman-Lerner Alejandro, Nolan Garry P, Nesvizhskii Alexey I, Peter Matthias, Loewith Robbie, von Mering Christian, Aebersold Ruedi", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Glucose intake hampers PKA-regulated HSP90 chaperone activity.", "journal": "eLife", "date": "2018-12-05", "authors": "Chen Yu-Chen, Jiang Pei-Heng, Chen Hsuan-Ming, Chen Chang-Han, Wang Yi-Ting, Chen Yu-Ju, Yu Chia-Jung, Teng Shu-Chun", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SAALRTPEQHPNDDNSSLAA", "down_seq": "HKGFFQKLGCC", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser527" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "415", "end_pos": "415" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "236", "end_pos": "236" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "422", "end_pos": "422" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "512", "end_pos": "512" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P23291-1.507.507", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P23291-1.512.512", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P23291-1.522.522", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P23291-1.523.523", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P23291-1.62.62", "start_pos": 62, "end_pos": 62, "uniprot_canonical_ac": "P23291-1", "length": 538, "uniprot_id": "KC11_YEAST", "protein_name": "Casein kinase I homolog 1", "refseq_ac": "NP_012003", "refseq_name": "serine/threonine protein kinase YCK1", "gene_name": "YCK1", "gene_names_uniprotkb": "YCK1; CKI2", "gene_names_refseq": "CKI2; YCK1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RSSMTATTAANSNSNSSRDD", "down_seq": "TIVGLHYKIGKKIGEGSFGV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177" }, { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser62" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "415", "end_pos": "415" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "236", "end_pos": "236" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "422", "end_pos": "422" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "512", "end_pos": "512" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P23291-1.43.43", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 18, "direction": "downstream", "id": "P23291-1.44.44", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P23291-1.46.46", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P23291-1.53.53", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P23291-1.55.55", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P23291-1.57.57", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P23291-1.58.58", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P23291-1.63.63", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P23291-1.63.63", "start_pos": 63, "end_pos": 63, "uniprot_canonical_ac": "P23291-1", "length": 538, "uniprot_id": "KC11_YEAST", "protein_name": "Casein kinase I homolog 1", "refseq_ac": "NP_012003", "refseq_name": "serine/threonine protein kinase YCK1", "gene_name": "YCK1", "gene_names_uniprotkb": "YCK1; CKI2", "gene_names_refseq": "CKI2; YCK1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-06-19", "authors": "Smolka Marcus B, Albuquerque Claudio P, Chen Sheng-hong, Zhou Huilin", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Mol. Cell. Proteomics", "date": "2008", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P23291", "url": "https://www.uniprot.org/uniprotkb/P23291" }, { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SSMTATTAANSNSNSSRDDS", "down_seq": "IVGLHYKIGKKIGEGSFGVL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P23291", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P23291" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001177", "url": "https://www.yeastgenome.org/locus/S000001177" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr63" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "415", "end_pos": "415" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "236", "end_pos": "236" }, { "start_pos": "238", "end_pos": "238" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "422", "end_pos": "422" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "493", "end_pos": "493" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "512", "end_pos": "512" }, { "start_pos": "522", "end_pos": "522" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "527", "end_pos": "527" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "63", "end_pos": "63" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P23291-1.43.43", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 19, "direction": "downstream", "id": "P23291-1.44.44", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P23291-1.46.46", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P23291-1.53.53", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P23291-1.55.55", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P23291-1.57.57", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P23291-1.58.58", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P23291-1.62.62", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.1112.1112", "start_pos": 1112, "end_pos": 1112, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "LNLRVKPPYIPEIKSPEDTS", "down_seq": "FEQEFTSAPPTLTPLPSVLT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Tyr1112" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "upstream", "id": "P24583-1.1125.1125", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.1125.1125", "start_pos": 1125, "end_pos": 1125, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "Methylglyoxal activates the target of rapamycin complex 2-protein kinase C signaling pathway in Saccharomyces cerevisiae.", "journal": "Molecular and cellular biology", "date": "2015-04", "authors": "Nomura Wataru, Inoue Yoshiharu", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "25624345", "url": "https://glygen.org/publication/PubMed/25624345" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "25624345", "url": "https://glygen.org/publication/PubMed/25624345", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "KSPEDTSYFEQEFTSAPPTL", "down_seq": "PLPSVLTTSQQEEFRGFSFM", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "25624345", "url": "https://glygen.org/publication/PubMed/25624345" }, { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr1125" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P24583-1.1112.1112", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P24583-1.1143.1143", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.1143.1143", "start_pos": 1143, "end_pos": 1143, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Functional counterparts of mammalian protein kinases PDK1 and SGK in budding yeast.", "journal": "Current biology : CB", "date": "1999-02-25", "authors": "Casamayor A, Torrance P D, Kobayashi T, Thorner J, Alessi D R", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "10074427", "url": "https://glygen.org/publication/PubMed/10074427" } ] }, { "title": "Methylglyoxal activates the target of rapamycin complex 2-protein kinase C signaling pathway in Saccharomyces cerevisiae.", "journal": "Molecular and cellular biology", "date": "2015-04", "authors": "Nomura Wataru, Inoue Yoshiharu", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "25624345", "url": "https://glygen.org/publication/PubMed/25624345" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "10074427", "url": "https://glygen.org/publication/PubMed/10074427", "database": "PubMed", "categories": [ "Other" ] }, { "id": "25624345", "url": "https://glygen.org/publication/PubMed/25624345", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TLTPLPSVLTTSQQEEFRGF", "down_seq": "FMPDDLDL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "10074427", "url": "https://glygen.org/publication/PubMed/10074427" }, { "database": "PubMed", "id": "25624345", "url": "https://glygen.org/publication/PubMed/25624345" }, { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser1143" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P24583-1.1125.1125", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.152.152", "start_pos": 152, "end_pos": 152, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "crossref": [ { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QYQEANTKLTKLYQIDGDQR", "down_seq": "SSAAEGGAMESKYRIQMLNK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Ser152" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.226.226", "start_pos": 226, "end_pos": 226, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QLTGVLTIGITAARDVDHIQ", "down_seq": "PMFARKPESYVTIKIDDTIK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser226" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.2.2", "start_pos": 2, "end_pos": 2, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "M", "down_seq": "FSQLEQNIKKKIAVEENIIR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser2" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P24583-1.4.4", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.31.31", "start_pos": 31, "end_pos": 31, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ], "crossref": [ { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "KKKIAVEENIIRGASALKKK", "down_seq": "SNVMVIQKCNTNIREARQNL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ], "site_lbl": "Thr31" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "P24583-1.32.32", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.32.32", "start_pos": 32, "end_pos": 32, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science", "date": "2009", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KKIAVEENIIRGASALKKKT", "down_seq": "NVMVIQKCNTNIREARQNLE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser32" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "P24583-1.31.31", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.4.4", "start_pos": 4, "end_pos": 4, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MSF", "down_seq": "QLEQNIKKKIAVEENIIRGA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser4" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P24583-1.2.2", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.570.570", "start_pos": 570, "end_pos": 570, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "RNQEKKKRTVPSAQLGSSIG", "down_seq": "ANGSDLSPSKLAERANAPLP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr570" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "P24583-1.574.574", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P24583-1.577.577", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P24583-1.579.579", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.574.574", "start_pos": 574, "end_pos": 574, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "crossref": [ { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KKKRTVPSAQLGSSIGTANG", "down_seq": "DLSPSKLAERANAPLPPQPR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Ser574" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P24583-1.570.570", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P24583-1.577.577", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P24583-1.579.579", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.577.577", "start_pos": 577, "end_pos": 577, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-06-19", "authors": "Smolka Marcus B, Albuquerque Claudio P, Chen Sheng-hong, Zhou Huilin", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RTVPSAQLGSSIGTANGSDL", "down_seq": "PSKLAERANAPLPPQPRKHD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser577" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P24583-1.570.570", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P24583-1.574.574", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P24583-1.579.579", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 7 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.579.579", "start_pos": 579, "end_pos": 579, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VPSAQLGSSIGTANGSDLSP", "down_seq": "KLAERANAPLPPQPRKHDKT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser579" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "P24583-1.570.570", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P24583-1.574.574", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P24583-1.577.577", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P24583-1.599.599", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.599.599", "start_pos": 599, "end_pos": 599, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.", "journal": "Genes & development", "date": "2009-08-15", "authors": "Huber Alexandre, Bodenmiller Bernd, Uotila Aino, Stahl Michael, Wanka Stefanie, Gerrits Bertran, Aebersold Ruedi, Loewith Robbie", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] }, { "title": "High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast.", "journal": "Proteomics", "date": "2009-10", "authors": "Gnad Florian, de Godoy Lyris M F, Cox J\u00fcrgen, Neuhauser Nadin, Ren Shubin, Olsen Jesper V, Mann Matthias", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" } ] }, { "title": "Global analysis of the yeast osmotic stress response by quantitative proteomics.", "journal": "Molecular bioSystems", "date": "2009-11", "authors": "Soufi Boumediene, Kelstrup Christian D, Stoehr Gabriele, Fr\u00f6hlich Florian, Walther Tobias C, Olsen Jesper V", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SKLAERANAPLPPQPRKHDK", "down_seq": "PSPQKVGRDSPTKQHDPIID", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr599" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P24583-1.579.579", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P24583-1.601.601", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P24583-1.609.609", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.601.601", "start_pos": 601, "end_pos": 601, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.", "journal": "Genes & development", "date": "2009-08-15", "authors": "Huber Alexandre, Bodenmiller Bernd, Uotila Aino, Stahl Michael, Wanka Stefanie, Gerrits Bertran, Aebersold Ruedi, Loewith Robbie", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] }, { "title": "High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast.", "journal": "Proteomics", "date": "2009-10", "authors": "Gnad Florian, de Godoy Lyris M F, Cox J\u00fcrgen, Neuhauser Nadin, Ren Shubin, Olsen Jesper V, Mann Matthias", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" } ] }, { "title": "Global analysis of the yeast osmotic stress response by quantitative proteomics.", "journal": "Molecular bioSystems", "date": "2009-11", "authors": "Soufi Boumediene, Kelstrup Christian D, Stoehr Gabriele, Fr\u00f6hlich Florian, Walther Tobias C, Olsen Jesper V", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LAERANAPLPPQPRKHDKTP", "down_seq": "PQKVGRDSPTKQHDPIIDKR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser601" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P24583-1.599.599", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P24583-1.609.609", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.609.609", "start_pos": 609, "end_pos": 609, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LPPQPRKHDKTPSPQKVGRD", "down_seq": "PTKQHDPIIDKRISLQTHGR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser609" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "P24583-1.599.599", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P24583-1.601.601", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P24583-1.623.623", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.623.623", "start_pos": 623, "end_pos": 623, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QKVGRDSPTKQHDPIIDKRI", "down_seq": "LQTHGREKLNKFIDENEAYL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser623" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "P24583-1.609.609", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.656.656", "start_pos": 656, "end_pos": 656, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] } ], "crossref": [ { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IDENEAYLNFTEGAQQTAEF", "down_seq": "SPEKTLDPTSNRRSLGLTDL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ], "site_lbl": "Ser656" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "P24583-1.657.657", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P24583-1.670.670", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.657.657", "start_pos": 657, "end_pos": 657, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DENEAYLNFTEGAQQTAEFS", "down_seq": "PEKTLDPTSNRRSLGLTDLS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser657" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "P24583-1.656.656", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P24583-1.670.670", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P24583-1.677.677", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.670.670", "start_pos": 670, "end_pos": 670, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QQTAEFSSPEKTLDPTSNRR", "down_seq": "LGLTDLSIEHSQTWESKDDL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser670" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "P24583-1.656.656", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P24583-1.657.657", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P24583-1.677.677", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P24583-1.681.681", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P24583-1.683.683", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P24583-1.686.686", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.677.677", "start_pos": 677, "end_pos": 677, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SPEKTLDPTSNRRSLGLTDL", "down_seq": "IEHSQTWESKDDLMRDELEL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser677" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P24583-1.657.657", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P24583-1.670.670", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P24583-1.681.681", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P24583-1.683.683", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P24583-1.686.686", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.681.681", "start_pos": 681, "end_pos": 681, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TLDPTSNRRSLGLTDLSIEH", "down_seq": "QTWESKDDLMRDELELWKAQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser681" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P24583-1.670.670", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P24583-1.677.677", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P24583-1.683.683", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P24583-1.686.686", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.683.683", "start_pos": 683, "end_pos": 683, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "DPTSNRRSLGLTDLSIEHSQ", "down_seq": "WESKDDLMRDELELWKAQRE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr683" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P24583-1.670.670", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P24583-1.677.677", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P24583-1.681.681", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P24583-1.686.686", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.686.686", "start_pos": 686, "end_pos": 686, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SNRRSLGLTDLSIEHSQTWE", "down_seq": "KDDLMRDELELWKAQREEME", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser686" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P24583-1.670.670", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P24583-1.677.677", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P24583-1.681.681", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P24583-1.683.683", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.747.747", "start_pos": 747, "end_pos": 747, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "LETKQKLDWENKNDFREADL", "down_seq": "IDSTHTNPFRDMNSETFQIE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr747" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "P24583-1.750.750", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P24583-1.751.751", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P24583-1.753.753", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P24583-1.761.761", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P24583-1.763.763", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.750.750", "start_pos": 750, "end_pos": 750, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KQKLDWENKNDFREADLTID", "down_seq": "THTNPFRDMNSETFQIEQDH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser750" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P24583-1.747.747", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P24583-1.751.751", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P24583-1.753.753", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P24583-1.761.761", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P24583-1.763.763", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.751.751", "start_pos": 751, "end_pos": 751, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "QKLDWENKNDFREADLTIDS", "down_seq": "HTNPFRDMNSETFQIEQDHA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr751" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P24583-1.747.747", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P24583-1.750.750", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P24583-1.753.753", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P24583-1.761.761", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P24583-1.763.763", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.753.753", "start_pos": 753, "end_pos": 753, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science", "date": "2009", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "LDWENKNDFREADLTIDSTH", "down_seq": "NPFRDMNSETFQIEQDHASK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr753" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "P24583-1.747.747", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P24583-1.750.750", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P24583-1.751.751", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P24583-1.761.761", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P24583-1.763.763", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P24583-1.772.772", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.75.75", "start_pos": 75, "end_pos": 75, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EDSLKKLRLKTAQQSQGENG", "down_seq": "EDNERCNSKEYGFLSTKSPN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser75" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "upstream", "id": "P24583-1.83.83", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P24583-1.93.93", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.761.761", "start_pos": 761, "end_pos": 761, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-06-19", "authors": "Smolka Marcus B, Albuquerque Claudio P, Chen Sheng-hong, Zhou Huilin", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science", "date": "2009", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FREADLTIDSTHTNPFRDMN", "down_seq": "ETFQIEQDHASKEVLQETVS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser761" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "P24583-1.747.747", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P24583-1.750.750", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P24583-1.751.751", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P24583-1.753.753", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P24583-1.763.763", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P24583-1.772.772", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P24583-1.779.779", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P24583-1.781.781", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 7 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.763.763", "start_pos": 763, "end_pos": 763, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "EADLTIDSTHTNPFRDMNSE", "down_seq": "FQIEQDHASKEVLQETVSLA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr763" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P24583-1.747.747", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P24583-1.750.750", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P24583-1.751.751", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P24583-1.753.753", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P24583-1.761.761", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P24583-1.772.772", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P24583-1.779.779", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P24583-1.781.781", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.772.772", "start_pos": 772, "end_pos": 772, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "HTNPFRDMNSETFQIEQDHA", "down_seq": "KEVLQETVSLAPTSTHASRT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser772" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P24583-1.753.753", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P24583-1.761.761", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P24583-1.763.763", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P24583-1.779.779", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P24583-1.781.781", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P24583-1.785.785", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P24583-1.786.786", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P24583-1.787.787", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P24583-1.790.790", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.779.779", "start_pos": 779, "end_pos": 779, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "MNSETFQIEQDHASKEVLQE", "down_seq": "VSLAPTSTHASRTTDQQSPQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr779" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P24583-1.761.761", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P24583-1.763.763", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P24583-1.772.772", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P24583-1.781.781", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P24583-1.785.785", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P24583-1.786.786", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P24583-1.787.787", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P24583-1.790.790", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P24583-1.797.797", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.781.781", "start_pos": 781, "end_pos": 781, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SETFQIEQDHASKEVLQETV", "down_seq": "LAPTSTHASRTTDQQSPQKS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser781" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P24583-1.761.761", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "downstream", "id": "P24583-1.763.763", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P24583-1.772.772", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P24583-1.779.779", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P24583-1.785.785", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P24583-1.786.786", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P24583-1.787.787", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P24583-1.790.790", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P24583-1.797.797", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P24583-1.801.801", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.785.785", "start_pos": 785, "end_pos": 785, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "QIEQDHASKEVLQETVSLAP", "down_seq": "STHASRTTDQQSPQKSQTST", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr785" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P24583-1.772.772", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P24583-1.779.779", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P24583-1.781.781", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P24583-1.786.786", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P24583-1.787.787", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P24583-1.790.790", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P24583-1.797.797", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P24583-1.801.801", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P24583-1.803.803", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P24583-1.804.804", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.786.786", "start_pos": 786, "end_pos": 786, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IEQDHASKEVLQETVSLAPT", "down_seq": "THASRTTDQQSPQKSQTSTS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser786" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "P24583-1.772.772", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P24583-1.779.779", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P24583-1.781.781", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P24583-1.785.785", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P24583-1.787.787", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P24583-1.790.790", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P24583-1.797.797", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P24583-1.801.801", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P24583-1.803.803", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P24583-1.804.804", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.787.787", "start_pos": 787, "end_pos": 787, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "EQDHASKEVLQETVSLAPTS", "down_seq": "HASRTTDQQSPQKSQTSTSA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr787" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P24583-1.772.772", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P24583-1.779.779", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P24583-1.781.781", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P24583-1.785.785", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P24583-1.786.786", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P24583-1.790.790", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P24583-1.797.797", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P24583-1.801.801", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P24583-1.803.803", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P24583-1.804.804", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.790.790", "start_pos": 790, "end_pos": 790, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "HASKEVLQETVSLAPTSTHA", "down_seq": "RTTDQQSPQKSQTSTSAKHK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser790" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P24583-1.772.772", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P24583-1.779.779", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P24583-1.781.781", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P24583-1.785.785", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P24583-1.786.786", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P24583-1.787.787", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P24583-1.797.797", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P24583-1.801.801", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P24583-1.803.803", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P24583-1.804.804", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.797.797", "start_pos": 797, "end_pos": 797, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QETVSLAPTSTHASRTTDQQ", "down_seq": "PQKSQTSTSAKHKKRAAKRR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser797" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P24583-1.779.779", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P24583-1.781.781", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P24583-1.785.785", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P24583-1.786.786", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P24583-1.787.787", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P24583-1.790.790", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P24583-1.801.801", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P24583-1.803.803", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P24583-1.804.804", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.801.801", "start_pos": 801, "end_pos": 801, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SLAPTSTHASRTTDQQSPQK", "down_seq": "QTSTSAKHKKRAAKRRKVSL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser801" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P24583-1.781.781", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P24583-1.785.785", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P24583-1.786.786", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P24583-1.787.787", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P24583-1.790.790", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P24583-1.797.797", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P24583-1.803.803", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P24583-1.804.804", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P24583-1.820.820", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.803.803", "start_pos": 803, "end_pos": 803, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "APTSTHASRTTDQQSPQKSQ", "down_seq": "STSAKHKKRAAKRRKVSLDN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr803" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P24583-1.785.785", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P24583-1.786.786", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P24583-1.787.787", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P24583-1.790.790", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P24583-1.797.797", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P24583-1.801.801", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P24583-1.804.804", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P24583-1.820.820", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.804.804", "start_pos": 804, "end_pos": 804, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PTSTHASRTTDQQSPQKSQT", "down_seq": "TSAKHKKRAAKRRKVSLDNF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser804" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P24583-1.785.785", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "downstream", "id": "P24583-1.786.786", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P24583-1.787.787", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P24583-1.790.790", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P24583-1.797.797", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P24583-1.801.801", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P24583-1.803.803", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P24583-1.820.820", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.820.820", "start_pos": 820, "end_pos": 820, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KSQTSTSAKHKKRAAKRRKV", "down_seq": "LDNFVLLKVLGKGNFGKVIL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser820" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P24583-1.801.801", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P24583-1.803.803", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P24583-1.804.804", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.83.83", "start_pos": 83, "end_pos": 83, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LKTAQQSQGENGSEDNERCN", "down_seq": "KEYGFLSTKSPNEHIFSRLD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser83" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "P24583-1.75.75", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P24583-1.93.93", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.93.93", "start_pos": 93, "end_pos": 93, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NGSEDNERCNSKEYGFLSTK", "down_seq": "PNEHIFSRLDLVKYDCPSLA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser93" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P24583-1.75.75", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P24583-1.83.83", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.981.981", "start_pos": 981, "end_pos": 981, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "GHIKIADYGLCKDEMWYGNR", "down_seq": "STFCGTPEFMAPEILKEQEY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr981" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "P24583-1.982.982", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P24583-1.983.983", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P24583-1.987.987", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.982.982", "start_pos": 982, "end_pos": 982, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ], "crossref": [ { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "HIKIADYGLCKDEMWYGNRT", "down_seq": "TFCGTPEFMAPEILKEQEYT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ], "site_lbl": "Ser982" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "P24583-1.981.981", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P24583-1.983.983", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P24583-1.987.987", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.983.983", "start_pos": 983, "end_pos": 983, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Functional counterparts of mammalian protein kinases PDK1 and SGK in budding yeast.", "journal": "Current biology : CB", "date": "1999-02-25", "authors": "Casamayor A, Torrance P D, Kobayashi T, Thorner J, Alessi D R", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "10074427", "url": "https://glygen.org/publication/PubMed/10074427" } ] }, { "title": "PDK1 homologs activate the Pkc1-mitogen-activated protein kinase pathway in yeast.", "journal": "Molecular and cellular biology", "date": "1999-12", "authors": "Inagaki M, Schmelzle T, Yamaguchi K, Irie K, Hall M N, Matsumoto K", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "10567559", "url": "https://glygen.org/publication/PubMed/10567559" } ] }, { "title": "Differential roles of PDK1- and PDK2-phosphorylation sites in the yeast AGC kinases Ypk1, Pkc1 and Sch9.", "journal": "Microbiology (Reading, England)", "date": "2004-10", "authors": "Roelants Fran\u00e7oise M, Torrance Pamela D, Thorner Jeremy", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "15470109", "url": "https://glygen.org/publication/PubMed/15470109" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "10074427", "url": "https://glygen.org/publication/PubMed/10074427", "database": "PubMed", "categories": [ "Other" ] }, { "id": "10567559", "url": "https://glygen.org/publication/PubMed/10567559", "database": "PubMed", "categories": [ "Other" ] }, { "id": "15470109", "url": "https://glygen.org/publication/PubMed/15470109", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "IKIADYGLCKDEMWYGNRTS", "down_seq": "FCGTPEFMAPEILKEQEYTK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "Q03407-1", "kinase_gene_name": "PKH1", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "10074427", "url": "https://glygen.org/publication/PubMed/10074427" }, { "database": "PubMed", "id": "10567559", "url": "https://glygen.org/publication/PubMed/10567559" }, { "database": "PubMed", "id": "15470109", "url": "https://glygen.org/publication/PubMed/15470109" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ], "site_lbl": "Thr983" }, { "kinase_uniprot_canonical_ac": "Q12236-1", "kinase_gene_name": "PKH2", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "10074427", "url": "https://glygen.org/publication/PubMed/10074427" }, { "database": "PubMed", "id": "10567559", "url": "https://glygen.org/publication/PubMed/10567559" }, { "database": "PubMed", "id": "15470109", "url": "https://glygen.org/publication/PubMed/15470109" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ], "site_lbl": "Thr983" }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "10567559", "url": "https://glygen.org/publication/PubMed/10567559" }, { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr983" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P24583-1.981.981", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P24583-1.982.982", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P24583-1.987.987", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P24583-1.987.987", "start_pos": 987, "end_pos": 987, "uniprot_canonical_ac": "P24583-1", "length": 1151, "uniprot_id": "KPC1_YEAST", "protein_name": "Protein kinase C-like 1", "refseq_ac": "NP_009445", "refseq_name": "protein kinase C", "gene_name": "PKC1", "gene_names_uniprotkb": "PKC1; HPO2; STT1; YBL0807", "gene_names_refseq": "CLY15; CLY5; CLY7; HPO2; PKC1; RSF8; STT1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P24583", "url": "https://www.uniprot.org/uniprotkb/P24583" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "DYGLCKDEMWYGNRTSTFCG", "down_seq": "PEFMAPEILKEQEYTKAVDW", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000201", "url": "https://www.yeastgenome.org/locus/S000000201" }, { "database": "iPTMnet", "id": "P24583", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P24583" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr987" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1112", "end_pos": "1112" }, { "start_pos": "1125", "end_pos": "1125" }, { "start_pos": "1143", "end_pos": "1143" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "570", "end_pos": "570" }, { "start_pos": "574", "end_pos": "574" }, { "start_pos": "577", "end_pos": "577" }, { "start_pos": "579", "end_pos": "579" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "601", "end_pos": "601" }, { "start_pos": "609", "end_pos": "609" }, { "start_pos": "623", "end_pos": "623" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "670", "end_pos": "670" }, { "start_pos": "677", "end_pos": "677" }, { "start_pos": "681", "end_pos": "681" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "686", "end_pos": "686" }, { "start_pos": "747", "end_pos": "747" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "751", "end_pos": "751" }, { "start_pos": "753", "end_pos": "753" }, { "start_pos": "75", "end_pos": "75" }, { "start_pos": "761", "end_pos": "761" }, { "start_pos": "763", "end_pos": "763" }, { "start_pos": "772", "end_pos": "772" }, { "start_pos": "779", "end_pos": "779" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "785", "end_pos": "785" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "790", "end_pos": "790" }, { "start_pos": "797", "end_pos": "797" }, { "start_pos": "801", "end_pos": "801" }, { "start_pos": "803", "end_pos": "803" }, { "start_pos": "804", "end_pos": "804" }, { "start_pos": "820", "end_pos": "820" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "93", "end_pos": "93" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "982", "end_pos": "982" }, { "start_pos": "983", "end_pos": "983" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "P24583-1.981.981", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P24583-1.982.982", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P24583-1.983.983", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25293-1.159.159", "start_pos": 159, "end_pos": 159, "uniprot_canonical_ac": "P25293-1", "length": 417, "uniprot_id": "NAP1_YEAST", "protein_name": "Nucleosome assembly protein", "refseq_ac": "NP_012974", "refseq_name": "histone chaperone NAP1", "gene_name": "NAP1", "gene_names_uniprotkb": "NAP1", "gene_names_refseq": "NAP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphorylation by casein kinase 2 regulates Nap1 localization and function.", "journal": "Molecular and cellular biology", "date": "2008-02", "authors": "Calvert Meredith E K, Keck Kristin M, Ptak Celeste, Shabanowitz Jeffrey, Hunt Donald F, Pemberton Lucy F", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] }, { "title": "Phosphorylation in the accessory domain of yeast histone chaperone protein 1 exposes the nuclear export signal sequence.", "journal": "Proteins", "date": "2022-02", "authors": "Ashida Sho, Morita Rikuri, Shigeta Yasuteru, Harada Ryuhei", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "34536244", "url": "https://glygen.org/publication/PubMed/34536244" } ] } ], "crossref": [ { "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000001756", "url": "https://www.yeastgenome.org/locus/S000001756", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34536244", "url": "https://glygen.org/publication/PubMed/34536244", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ISGQEQPKPEQIAKGQEIVE", "down_seq": "LNETELLVDEEEKAQNDSEE", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Significant reduction in phosphorylation; when associated with A-397. Complete inhibition of phosphorylation; when associated with A-177 and A-397. Leads to a prolonged S phase and a shortened passage through G1; when associated with A-177 and A-397. Predominantly cytoplasmic; when associated with S-99, A-177 and A-397.", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "PubMed", "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883" } ] }, { "sequence_org": "S", "sequence_mut": "D", "comment": "Leads to a prolonged S phase and a shortened passage through G1; when associated with A-177 and A-397.", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "PubMed", "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P15790-1", "kinase_gene_name": "CKA1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" }, { "database": "PubMed", "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883" } ], "site_lbl": "Ser159" }, { "kinase_uniprot_canonical_ac": "P19454-1", "kinase_gene_name": "CKA2", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" }, { "database": "PubMed", "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883" } ], "site_lbl": "Ser159" }, { "kinase_uniprot_canonical_ac": "P38930-1", "kinase_gene_name": "CKB2", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" }, { "database": "PubMed", "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883" } ], "site_lbl": "Ser159" }, { "kinase_uniprot_canonical_ac": "P43639-1", "kinase_gene_name": "CKB1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" }, { "database": "PubMed", "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883" } ], "site_lbl": "Ser159" }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by CK2", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "SGD", "id": "S000001756", "url": "https://www.yeastgenome.org/locus/S000001756" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34536244", "url": "https://glygen.org/publication/PubMed/34536244" }, { "database": "PubMed", "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883" } ], "site_lbl": "Ser159" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "288", "end_pos": "292" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "290", "end_pos": "305" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "99", "end_pos": "99" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "104", "end_pos": "104" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "33", "end_pos": "33" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "mutagenesis_flag", "phosphorylation_flag" ], "glycosylation": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P25293-1.140.140", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P25293-1.177.177", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25293-1.177.177", "start_pos": 177, "end_pos": 177, "uniprot_canonical_ac": "P25293-1", "length": 417, "uniprot_id": "NAP1_YEAST", "protein_name": "Nucleosome assembly protein", "refseq_ac": "NP_012974", "refseq_name": "histone chaperone NAP1", "gene_name": "NAP1", "gene_names_uniprotkb": "NAP1", "gene_names_refseq": "NAP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphorylation by casein kinase 2 regulates Nap1 localization and function.", "journal": "Molecular and cellular biology", "date": "2008-02", "authors": "Calvert Meredith E K, Keck Kristin M, Ptak Celeste, Shabanowitz Jeffrey, Hunt Donald F, Pemberton Lucy F", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883" } ] }, { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "Journal of proteome research", "date": "2007-03", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-06-19", "authors": "Smolka Marcus B, Albuquerque Claudio P, Chen Sheng-hong, Zhou Huilin", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.", "journal": "Genes & development", "date": "2009-08-15", "authors": "Huber Alexandre, Bodenmiller Bernd, Uotila Aino, Stahl Michael, Wanka Stefanie, Gerrits Bertran, Aebersold Ruedi, Loewith Robbie", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast.", "journal": "Proteomics", "date": "2009-10", "authors": "Gnad Florian, de Godoy Lyris M F, Cox J\u00fcrgen, Neuhauser Nadin, Ren Shubin, Olsen Jesper V, Mann Matthias", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" } ] }, { "title": "Global analysis of the yeast osmotic stress response by quantitative proteomics.", "journal": "Molecular bioSystems", "date": "2009-11", "authors": "Soufi Boumediene, Kelstrup Christian D, Stoehr Gabriele, Fr\u00f6hlich Florian, Walther Tobias C, Olsen Jesper V", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] }, { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] }, { "title": "Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast.", "journal": "Science signaling", "date": "2010-12-21", "authors": "Bodenmiller Bernd, Wanka Stefanie, Kraft Claudine, Urban J\u00f6rg, Campbell David, Pedrioli Patrick G, Gerrits Bertran, Picotti Paola, Lam Henry, Vitek Olga, Brusniak Mi-Youn, Roschitzki Bernd, Zhang Chao, Shokat Kevan M, Schlapbach Ralph, Colman-Lerner Alejandro, Nolan Garry P, Nesvizhskii Alexey I, Peter Matthias, Loewith Robbie, von Mering Christian, Aebersold Ruedi", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "title": "Global mapping of protein phosphorylation events identifies Ste20, Sch9 and the cell-cycle regulatory kinases Cdc28/Pho85 as mediators of fatty acid starvation responses in Saccharomyces cerevisiae.", "journal": "Molecular bioSystems", "date": "2012-03", "authors": "Pultz Dennis, Bennetzen Martin V, R\u00f8dk\u00e6r Steven Vestergaard, Zimmermann Christine, Enserink Jorrit M, Andersen Jens S, F\u00e6rgeman Nils J", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] }, { "title": "Phosphorylation in the accessory domain of yeast histone chaperone protein 1 exposes the nuclear export signal sequence.", "journal": "Proteins", "date": "2022-02", "authors": "Ashida Sho, Morita Rikuri, Shigeta Yasuteru, Harada Ryuhei", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "34536244", "url": "https://glygen.org/publication/PubMed/34536244" } ] } ], "crossref": [ { "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000001756", "url": "https://www.yeastgenome.org/locus/S000001756", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34536244", "url": "https://glygen.org/publication/PubMed/34536244", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VESLNETELLVDEEEKAQND", "down_seq": "EEEQVKGIPSFWLTALENLP", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Significant reduction in phosphorylation; when associated with A-397. Complete inhibition of phosphorylation; when associated with A-159 and A-397. Leads to a prolonged S phase and a shortened passage through G1; when associated with A-159 and A-397. Predominantly cytoplasmic; when associated with S-99, A-159 and A-397.", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "PubMed", "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883" } ] }, { "sequence_org": "S", "sequence_mut": "D", "comment": "Leads to a prolonged S phase and a shortened passage through G1; when associated with A-159 and A-397.", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "PubMed", "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P15790-1", "kinase_gene_name": "CKA1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ], "site_lbl": "Ser177" }, { "kinase_uniprot_canonical_ac": "P19454-1", "kinase_gene_name": "CKA2", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ], "site_lbl": "Ser177" }, { "kinase_uniprot_canonical_ac": "P38930-1", "kinase_gene_name": "CKB2", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ], "site_lbl": "Ser177" }, { "kinase_uniprot_canonical_ac": "P43639-1", "kinase_gene_name": "CKB1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ], "site_lbl": "Ser177" }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by CK2", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "SGD", "id": "S000001756", "url": "https://www.yeastgenome.org/locus/S000001756" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34536244", "url": "https://glygen.org/publication/PubMed/34536244" }, { "database": "PubMed", "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ], "site_lbl": "Ser177" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "288", "end_pos": "292" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "290", "end_pos": "305" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "99", "end_pos": "99" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "104", "end_pos": "104" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "33", "end_pos": "33" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "mutagenesis_flag", "phosphorylation_flag" ], "glycosylation": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P25293-1.159.159", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 17 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25293-1.288.292", "start_pos": 288, "end_pos": 292, "uniprot_canonical_ac": "P25293-1", "length": 417, "uniprot_id": "NAP1_YEAST", "protein_name": "Nucleosome assembly protein", "refseq_ac": "NP_012974", "refseq_name": "histone chaperone NAP1", "gene_name": "NAP1", "gene_names_uniprotkb": "NAP1", "gene_names_refseq": "NAP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Nap1 and Kap114 co-chaperone H2A-H2B and facilitate targeted histone release in the nucleus.", "journal": "The Journal of cell biology", "date": "2025-01-06", "authors": "Fung Ho Yee Joyce, Jiou Jenny, Niesman Ashley B, Bernardes Natalia E, Chook Yuh Min", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" } ], "reference": [ { "type": "PubMed", "id": "39601790", "url": "https://glygen.org/publication/PubMed/39601790" } ] } ], "crossref": [ { "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "39601790", "url": "https://glygen.org/publication/PubMed/39601790", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "EMRKQ", "start_aa": "E", "up_seq": "HAEGCEISWKDNAHNVTVDL", "down_seq": "RNKTTKQVRTIEKITPIESF", "mutagenesis": [ { "sequence_org": "EMRKQ", "sequence_mut": "AMAKA", "comment": "Abolishes the interaction with KAP114.", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "PubMed", "id": "39601790", "url": "https://glygen.org/publication/PubMed/39601790" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "288", "end_pos": "292" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "290", "end_pos": "305" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "99", "end_pos": "99" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "104", "end_pos": "104" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "33", "end_pos": "33" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P25293-1.290.290", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P25293-1.290.305", "categories": [ "mutagenesis_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P25293-1.305.305", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25293-1.290.290", "start_pos": 290, "end_pos": 290, "uniprot_canonical_ac": "P25293-1", "length": 417, "uniprot_id": "NAP1_YEAST", "protein_name": "Nucleosome assembly protein", "refseq_ac": "NP_012974", "refseq_name": "histone chaperone NAP1", "gene_name": "NAP1", "gene_names_uniprotkb": "NAP1", "gene_names_refseq": "NAP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A beta-hairpin comprising the nuclear localization sequence sustains the self-associated states of nucleosome assembly protein 1.", "journal": "Journal of molecular biology", "date": "2008-01-25", "authors": "Park Young-Jun, McBryant Steven J, Luger Karolin", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" } ], "reference": [ { "type": "PubMed", "id": "18068721", "url": "https://glygen.org/publication/PubMed/18068721" } ] } ], "crossref": [ { "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18068721", "url": "https://glygen.org/publication/PubMed/18068721", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "EGCEISWKDNAHNVTVDLEM", "down_seq": "KQRNKTTKQVRTIEKITPIE", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "P", "comment": "Disrupts oligomerization of NAP1 dimers.", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "PubMed", "id": "18068721", "url": "https://glygen.org/publication/PubMed/18068721" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "288", "end_pos": "292" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "290", "end_pos": "305" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "99", "end_pos": "99" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "104", "end_pos": "104" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "33", "end_pos": "33" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P25293-1.288.292", "categories": [ "mutagenesis_flag" ] }, { "distance": 0, "direction": "upstream", "id": "P25293-1.290.305", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P25293-1.305.305", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25293-1.290.305", "start_pos": 290, "end_pos": 305, "uniprot_canonical_ac": "P25293-1", "length": 417, "uniprot_id": "NAP1_YEAST", "protein_name": "Nucleosome assembly protein", "refseq_ac": "NP_012974", "refseq_name": "histone chaperone NAP1", "gene_name": "NAP1", "gene_names_uniprotkb": "NAP1", "gene_names_refseq": "NAP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A beta-hairpin comprising the nuclear localization sequence sustains the self-associated states of nucleosome assembly protein 1.", "journal": "Journal of molecular biology", "date": "2008-01-25", "authors": "Park Young-Jun, McBryant Steven J, Luger Karolin", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" } ], "reference": [ { "type": "PubMed", "id": "18068721", "url": "https://glygen.org/publication/PubMed/18068721" } ] } ], "crossref": [ { "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18068721", "url": "https://glygen.org/publication/PubMed/18068721", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "RKQRNKTTKQVRTIEK", "start_aa": "R", "up_seq": "EGCEISWKDNAHNVTVDLEM", "down_seq": "ITPIESFFNFFDPPKIQNED", "mutagenesis": [ { "sequence_org": "RKQRNKTTKQVRTIEK", "sequence_mut": "PKQRNKTTKQVPPIEP", "comment": "Disrupts oligomerization of NAP1 dimers.", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "PubMed", "id": "18068721", "url": "https://glygen.org/publication/PubMed/18068721" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "288", "end_pos": "292" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "290", "end_pos": "305" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "99", "end_pos": "99" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "104", "end_pos": "104" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "33", "end_pos": "33" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P25293-1.288.292", "categories": [ "mutagenesis_flag" ] }, { "distance": 0, "direction": "downstream", "id": "P25293-1.290.290", "categories": [ "mutagenesis_flag" ] }, { "distance": 0, "direction": "upstream", "id": "P25293-1.305.305", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25293-1.305.305", "start_pos": 305, "end_pos": 305, "uniprot_canonical_ac": "P25293-1", "length": 417, "uniprot_id": "NAP1_YEAST", "protein_name": "Nucleosome assembly protein", "refseq_ac": "NP_012974", "refseq_name": "histone chaperone NAP1", "gene_name": "NAP1", "gene_names_uniprotkb": "NAP1", "gene_names_refseq": "NAP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A beta-hairpin comprising the nuclear localization sequence sustains the self-associated states of nucleosome assembly protein 1.", "journal": "Journal of molecular biology", "date": "2008-01-25", "authors": "Park Young-Jun, McBryant Steven J, Luger Karolin", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" } ], "reference": [ { "type": "PubMed", "id": "18068721", "url": "https://glygen.org/publication/PubMed/18068721" } ] } ], "crossref": [ { "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18068721", "url": "https://glygen.org/publication/PubMed/18068721", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "VDLEMRKQRNKTTKQVRTIE", "down_seq": "ITPIESFFNFFDPPKIQNED", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "P", "comment": "Disrupts oligomerization of NAP1 dimers.", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "PubMed", "id": "18068721", "url": "https://glygen.org/publication/PubMed/18068721" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "288", "end_pos": "292" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "290", "end_pos": "305" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "99", "end_pos": "99" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "104", "end_pos": "104" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "33", "end_pos": "33" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P25293-1.288.292", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P25293-1.290.290", "categories": [ "mutagenesis_flag" ] }, { "distance": 0, "direction": "downstream", "id": "P25293-1.290.305", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25293-1.397.397", "start_pos": 397, "end_pos": 397, "uniprot_canonical_ac": "P25293-1", "length": 417, "uniprot_id": "NAP1_YEAST", "protein_name": "Nucleosome assembly protein", "refseq_ac": "NP_012974", "refseq_name": "histone chaperone NAP1", "gene_name": "NAP1", "gene_names_uniprotkb": "NAP1", "gene_names_refseq": "NAP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphorylation by casein kinase 2 regulates Nap1 localization and function.", "journal": "Molecular and cellular biology", "date": "2008-02", "authors": "Calvert Meredith E K, Keck Kristin M, Ptak Celeste, Shabanowitz Jeffrey, Hunt Donald F, Pemberton Lucy F", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883" } ] } ], "crossref": [ { "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DEDEDEEEDDDHGLEDDDGE", "down_seq": "AEEQDDFAGRPEQAPECKQS", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Significant reduction in phosphorylation; when associated with either A-159 or A-177. Complete inhibition of phosphorylation; when associated with A-159 and A-177. Leads to a prolonged S phase and a shortened passage through G1; when associated with A-159 and A-177. Predominantly cytoplasmic; when associated with S-99; A-159 and A-177.", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "PubMed", "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883" } ] }, { "sequence_org": "S", "sequence_mut": "D", "comment": "Leads to a prolonged S phase and a shortened passage through G1; when associated with A-159 and A-177.", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "PubMed", "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P15790-1", "kinase_gene_name": "CKA1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" }, { "database": "PubMed", "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883" } ], "site_lbl": "Ser397" }, { "kinase_uniprot_canonical_ac": "P19454-1", "kinase_gene_name": "CKA2", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" }, { "database": "PubMed", "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883" } ], "site_lbl": "Ser397" }, { "kinase_uniprot_canonical_ac": "P38930-1", "kinase_gene_name": "CKB2", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" }, { "database": "PubMed", "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883" } ], "site_lbl": "Ser397" }, { "kinase_uniprot_canonical_ac": "P43639-1", "kinase_gene_name": "CKB1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" }, { "database": "PubMed", "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883" } ], "site_lbl": "Ser397" }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by CK2", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" }, { "database": "PubMed", "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883" } ], "site_lbl": "Ser397" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "288", "end_pos": "292" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "290", "end_pos": "305" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "99", "end_pos": "99" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "104", "end_pos": "104" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "33", "end_pos": "33" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "mutagenesis_flag", "phosphorylation_flag" ], "glycosylation": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25293-1.99.99", "start_pos": 99, "end_pos": 99, "uniprot_canonical_ac": "P25293-1", "length": 417, "uniprot_id": "NAP1_YEAST", "protein_name": "Nucleosome assembly protein", "refseq_ac": "NP_012974", "refseq_name": "histone chaperone NAP1", "gene_name": "NAP1", "gene_names_uniprotkb": "NAP1", "gene_names_refseq": "NAP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphorylation by casein kinase 2 regulates Nap1 localization and function.", "journal": "Molecular and cellular biology", "date": "2008-02", "authors": "Calvert Meredith E K, Keck Kristin M, Ptak Celeste, Shabanowitz Jeffrey, Hunt Donald F, Pemberton Lucy F", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883" } ] } ], "crossref": [ { "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "GQDSGYVGGLPKNVKEKLLS", "down_seq": "KTLQSELFEVEKEFQVEMFE", "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "S", "comment": "Predominantly cytoplasmic; when associated with A-159, A-177 and S-397.", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "PubMed", "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "288", "end_pos": "292" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "290", "end_pos": "305" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "99", "end_pos": "99" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "104", "end_pos": "104" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "33", "end_pos": "33" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P25293-1.82.82", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P25293-1.84.84", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P25293-1.98.98", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P25293-1.104.104", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25293-1.104.104", "start_pos": 104, "end_pos": 104, "uniprot_canonical_ac": "P25293-1", "length": 417, "uniprot_id": "NAP1_YEAST", "protein_name": "Nucleosome assembly protein", "refseq_ac": "NP_012974", "refseq_name": "histone chaperone NAP1", "gene_name": "NAP1", "gene_names_uniprotkb": "NAP1", "gene_names_refseq": "NAP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphorylation by casein kinase 2 regulates Nap1 localization and function.", "journal": "Molecular and cellular biology", "date": "2008-02", "authors": "Calvert Meredith E K, Keck Kristin M, Ptak Celeste, Shabanowitz Jeffrey, Hunt Donald F, Pemberton Lucy F", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000001756", "url": "https://www.yeastgenome.org/locus/S000001756", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "YVGGLPKNVKEKLLSLKTLQ", "down_seq": "ELFEVEKEFQVEMFELENKF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "PubMed", "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883" }, { "database": "SGD", "id": "S000001756", "url": "https://www.yeastgenome.org/locus/S000001756" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser104" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "288", "end_pos": "292" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "290", "end_pos": "305" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "99", "end_pos": "99" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "104", "end_pos": "104" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "33", "end_pos": "33" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P25293-1.84.84", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P25293-1.98.98", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P25293-1.99.99", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25293-1.11.11", "start_pos": 11, "end_pos": 11, "uniprot_canonical_ac": "P25293-1", "length": 417, "uniprot_id": "NAP1_YEAST", "protein_name": "Nucleosome assembly protein", "refseq_ac": "NP_012974", "refseq_name": "histone chaperone NAP1", "gene_name": "NAP1", "gene_names_uniprotkb": "NAP1", "gene_names_refseq": "NAP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ], "crossref": [ { "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000001756", "url": "https://www.yeastgenome.org/locus/S000001756", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MSDPIRTKPK", "down_seq": "SMQIDNAPTPHNTPASVLNP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000001756", "url": "https://www.yeastgenome.org/locus/S000001756" } ], "site_lbl": "Ser11" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "288", "end_pos": "292" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "290", "end_pos": "305" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "99", "end_pos": "99" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "104", "end_pos": "104" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "33", "end_pos": "33" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "P25293-1.2.2", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P25293-1.12.12", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P25293-1.20.20", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P25293-1.24.24", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P25293-1.27.27", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25293-1.12.12", "start_pos": 12, "end_pos": 12, "uniprot_canonical_ac": "P25293-1", "length": 417, "uniprot_id": "NAP1_YEAST", "protein_name": "Nucleosome assembly protein", "refseq_ac": "NP_012974", "refseq_name": "histone chaperone NAP1", "gene_name": "NAP1", "gene_names_uniprotkb": "NAP1", "gene_names_refseq": "NAP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] } ], "crossref": [ { "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MSDPIRTKPKS", "down_seq": "MQIDNAPTPHNTPASVLNPS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ], "site_lbl": "Ser12" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "288", "end_pos": "292" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "290", "end_pos": "305" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "99", "end_pos": "99" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "104", "end_pos": "104" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "33", "end_pos": "33" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "P25293-1.2.2", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P25293-1.11.11", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P25293-1.20.20", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P25293-1.24.24", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P25293-1.27.27", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P25293-1.32.32", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25293-1.140.140", "start_pos": 140, "end_pos": 140, "uniprot_canonical_ac": "P25293-1", "length": 417, "uniprot_id": "NAP1_YEAST", "protein_name": "Nucleosome assembly protein", "refseq_ac": "NP_012974", "refseq_name": "histone chaperone NAP1", "gene_name": "NAP1", "gene_names_uniprotkb": "NAP1", "gene_names_refseq": "NAP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphorylation by casein kinase 2 regulates Nap1 localization and function.", "journal": "Molecular and cellular biology", "date": "2008-02", "authors": "Calvert Meredith E K, Keck Kristin M, Ptak Celeste, Shabanowitz Jeffrey, Hunt Donald F, Pemberton Lucy F", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-06-19", "authors": "Smolka Marcus B, Albuquerque Claudio P, Chen Sheng-hong, Zhou Huilin", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] }, { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast.", "journal": "Science signaling", "date": "2010-12-21", "authors": "Bodenmiller Bernd, Wanka Stefanie, Kraft Claudine, Urban J\u00f6rg, Campbell David, Pedrioli Patrick G, Gerrits Bertran, Picotti Paola, Lam Henry, Vitek Olga, Brusniak Mi-Youn, Roschitzki Bernd, Zhang Chao, Shokat Kevan M, Schlapbach Ralph, Colman-Lerner Alejandro, Nolan Garry P, Nesvizhskii Alexey I, Peter Matthias, Loewith Robbie, von Mering Christian, Aebersold Ruedi", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] }, { "title": "Phosphorylation in the accessory domain of yeast histone chaperone protein 1 exposes the nuclear export signal sequence.", "journal": "Proteins", "date": "2022-02", "authors": "Ashida Sho, Morita Rikuri, Shigeta Yasuteru, Harada Ryuhei", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "34536244", "url": "https://glygen.org/publication/PubMed/34536244" } ] } ], "crossref": [ { "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000001756", "url": "https://www.yeastgenome.org/locus/S000001756", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34536244", "url": "https://glygen.org/publication/PubMed/34536244", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LENKFLQKYKPIWEQRSRII", "down_seq": "GQEQPKPEQIAKGQEIVESL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "PubMed", "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001756", "url": "https://www.yeastgenome.org/locus/S000001756" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34536244", "url": "https://glygen.org/publication/PubMed/34536244" } ], "site_lbl": "Ser140" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "288", "end_pos": "292" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "290", "end_pos": "305" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "99", "end_pos": "99" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "104", "end_pos": "104" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "33", "end_pos": "33" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "upstream", "id": "P25293-1.159.159", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 10 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25293-1.20.20", "start_pos": 20, "end_pos": 20, "uniprot_canonical_ac": "P25293-1", "length": 417, "uniprot_id": "NAP1_YEAST", "protein_name": "Nucleosome assembly protein", "refseq_ac": "NP_012974", "refseq_name": "histone chaperone NAP1", "gene_name": "NAP1", "gene_names_uniprotkb": "NAP1", "gene_names_refseq": "NAP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "Journal of proteome research", "date": "2007-03", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.", "journal": "Molecular & cellular proteomics : MCP", "date": "2005-03", "authors": "Gruhler Albrecht, Olsen Jesper V, Mohammed Shabaz, Mortensen Peter, Faergeman Nils J, Mann Matthias, Jensen Ole N", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" } ] }, { "title": "Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-06-19", "authors": "Smolka Marcus B, Albuquerque Claudio P, Chen Sheng-hong, Zhou Huilin", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] }, { "title": "Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.", "journal": "Genes & development", "date": "2009-08-15", "authors": "Huber Alexandre, Bodenmiller Bernd, Uotila Aino, Stahl Michael, Wanka Stefanie, Gerrits Bertran, Aebersold Ruedi, Loewith Robbie", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] }, { "title": "High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast.", "journal": "Proteomics", "date": "2009-10", "authors": "Gnad Florian, de Godoy Lyris M F, Cox J\u00fcrgen, Neuhauser Nadin, Ren Shubin, Olsen Jesper V, Mann Matthias", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" } ] }, { "title": "Global analysis of the yeast osmotic stress response by quantitative proteomics.", "journal": "Molecular bioSystems", "date": "2009-11", "authors": "Soufi Boumediene, Kelstrup Christian D, Stoehr Gabriele, Fr\u00f6hlich Florian, Walther Tobias C, Olsen Jesper V", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] }, { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast.", "journal": "Science signaling", "date": "2010-12-21", "authors": "Bodenmiller Bernd, Wanka Stefanie, Kraft Claudine, Urban J\u00f6rg, Campbell David, Pedrioli Patrick G, Gerrits Bertran, Picotti Paola, Lam Henry, Vitek Olga, Brusniak Mi-Youn, Roschitzki Bernd, Zhang Chao, Shokat Kevan M, Schlapbach Ralph, Colman-Lerner Alejandro, Nolan Garry P, Nesvizhskii Alexey I, Peter Matthias, Loewith Robbie, von Mering Christian, Aebersold Ruedi", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Glucose intake hampers PKA-regulated HSP90 chaperone activity.", "journal": "eLife", "date": "2018-12-05", "authors": "Chen Yu-Chen, Jiang Pei-Heng, Chen Hsuan-Ming, Chen Chang-Han, Wang Yi-Ting, Chen Yu-Ju, Yu Chia-Jung, Teng Shu-Chun", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000001756", "url": "https://www.yeastgenome.org/locus/S000001756", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "", "down_seq": "PHNTPASVLNPSYLKNGNPV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001756", "url": "https://www.yeastgenome.org/locus/S000001756" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr20" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "288", "end_pos": "292" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "290", "end_pos": "305" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "99", "end_pos": "99" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "104", "end_pos": "104" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "33", "end_pos": "33" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P25293-1.2.2", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P25293-1.11.11", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P25293-1.12.12", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P25293-1.24.24", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P25293-1.27.27", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P25293-1.32.32", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P25293-1.33.33", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 16 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25293-1.237.237", "start_pos": 237, "end_pos": 237, "uniprot_canonical_ac": "P25293-1", "length": 417, "uniprot_id": "NAP1_YEAST", "protein_name": "Nucleosome assembly protein", "refseq_ac": "NP_012974", "refseq_name": "histone chaperone NAP1", "gene_name": "NAP1", "gene_names_uniprotkb": "NAP1", "gene_names_refseq": "NAP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000001756", "url": "https://www.yeastgenome.org/locus/S000001756", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IGLEYLTDGRPGFKLLFRFD", "down_seq": "SANPFFTNDILCKTYFYQKE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000001756", "url": "https://www.yeastgenome.org/locus/S000001756" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser237" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "288", "end_pos": "292" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "290", "end_pos": "305" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "99", "end_pos": "99" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "104", "end_pos": "104" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "33", "end_pos": "33" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25293-1.24.24", "start_pos": 24, "end_pos": 24, "uniprot_canonical_ac": "P25293-1", "length": 417, "uniprot_id": "NAP1_YEAST", "protein_name": "Nucleosome assembly protein", "refseq_ac": "NP_012974", "refseq_name": "histone chaperone NAP1", "gene_name": "NAP1", "gene_names_uniprotkb": "NAP1", "gene_names_refseq": "NAP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "Journal of proteome research", "date": "2007-03", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.", "journal": "Molecular & cellular proteomics : MCP", "date": "2005-03", "authors": "Gruhler Albrecht, Olsen Jesper V, Mohammed Shabaz, Mortensen Peter, Faergeman Nils J, Mann Matthias, Jensen Ole N", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" } ] }, { "title": "Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.", "journal": "Genes & development", "date": "2009-08-15", "authors": "Huber Alexandre, Bodenmiller Bernd, Uotila Aino, Stahl Michael, Wanka Stefanie, Gerrits Bertran, Aebersold Ruedi, Loewith Robbie", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] }, { "title": "High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast.", "journal": "Proteomics", "date": "2009-10", "authors": "Gnad Florian, de Godoy Lyris M F, Cox J\u00fcrgen, Neuhauser Nadin, Ren Shubin, Olsen Jesper V, Mann Matthias", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" } ] }, { "title": "Global analysis of the yeast osmotic stress response by quantitative proteomics.", "journal": "Molecular bioSystems", "date": "2009-11", "authors": "Soufi Boumediene, Kelstrup Christian D, Stoehr Gabriele, Fr\u00f6hlich Florian, Walther Tobias C, Olsen Jesper V", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] }, { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast.", "journal": "Science signaling", "date": "2010-12-21", "authors": "Bodenmiller Bernd, Wanka Stefanie, Kraft Claudine, Urban J\u00f6rg, Campbell David, Pedrioli Patrick G, Gerrits Bertran, Picotti Paola, Lam Henry, Vitek Olga, Brusniak Mi-Youn, Roschitzki Bernd, Zhang Chao, Shokat Kevan M, Schlapbach Ralph, Colman-Lerner Alejandro, Nolan Garry P, Nesvizhskii Alexey I, Peter Matthias, Loewith Robbie, von Mering Christian, Aebersold Ruedi", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Glucose intake hampers PKA-regulated HSP90 chaperone activity.", "journal": "eLife", "date": "2018-12-05", "authors": "Chen Yu-Chen, Jiang Pei-Heng, Chen Hsuan-Ming, Chen Chang-Han, Wang Yi-Ting, Chen Yu-Ju, Yu Chia-Jung, Teng Shu-Chun", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000001756", "url": "https://www.yeastgenome.org/locus/S000001756", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PIRTKPKSSMQIDNAPTPHN", "down_seq": "PASVLNPSYLKNGNPVRAQA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001756", "url": "https://www.yeastgenome.org/locus/S000001756" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr24" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "288", "end_pos": "292" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "290", "end_pos": "305" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "99", "end_pos": "99" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "104", "end_pos": "104" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "33", "end_pos": "33" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P25293-1.11.11", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P25293-1.12.12", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P25293-1.20.20", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P25293-1.27.27", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P25293-1.32.32", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P25293-1.33.33", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 15 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25293-1.27.27", "start_pos": 27, "end_pos": 27, "uniprot_canonical_ac": "P25293-1", "length": 417, "uniprot_id": "NAP1_YEAST", "protein_name": "Nucleosome assembly protein", "refseq_ac": "NP_012974", "refseq_name": "histone chaperone NAP1", "gene_name": "NAP1", "gene_names_uniprotkb": "NAP1", "gene_names_refseq": "NAP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "Journal of proteome research", "date": "2007-03", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.", "journal": "Genes & development", "date": "2009-08-15", "authors": "Huber Alexandre, Bodenmiller Bernd, Uotila Aino, Stahl Michael, Wanka Stefanie, Gerrits Bertran, Aebersold Ruedi, Loewith Robbie", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] }, { "title": "High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast.", "journal": "Proteomics", "date": "2009-10", "authors": "Gnad Florian, de Godoy Lyris M F, Cox J\u00fcrgen, Neuhauser Nadin, Ren Shubin, Olsen Jesper V, Mann Matthias", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" } ] }, { "title": "Global analysis of the yeast osmotic stress response by quantitative proteomics.", "journal": "Molecular bioSystems", "date": "2009-11", "authors": "Soufi Boumediene, Kelstrup Christian D, Stoehr Gabriele, Fr\u00f6hlich Florian, Walther Tobias C, Olsen Jesper V", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] }, { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast.", "journal": "Science signaling", "date": "2010-12-21", "authors": "Bodenmiller Bernd, Wanka Stefanie, Kraft Claudine, Urban J\u00f6rg, Campbell David, Pedrioli Patrick G, Gerrits Bertran, Picotti Paola, Lam Henry, Vitek Olga, Brusniak Mi-Youn, Roschitzki Bernd, Zhang Chao, Shokat Kevan M, Schlapbach Ralph, Colman-Lerner Alejandro, Nolan Garry P, Nesvizhskii Alexey I, Peter Matthias, Loewith Robbie, von Mering Christian, Aebersold Ruedi", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Glucose intake hampers PKA-regulated HSP90 chaperone activity.", "journal": "eLife", "date": "2018-12-05", "authors": "Chen Yu-Chen, Jiang Pei-Heng, Chen Hsuan-Ming, Chen Chang-Han, Wang Yi-Ting, Chen Yu-Ju, Yu Chia-Jung, Teng Shu-Chun", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000001756", "url": "https://www.yeastgenome.org/locus/S000001756", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TKPKSSMQIDNAPTPHNTPA", "down_seq": "VLNPSYLKNGNPVRAQAQEQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001756", "url": "https://www.yeastgenome.org/locus/S000001756" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser27" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "288", "end_pos": "292" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "290", "end_pos": "305" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "99", "end_pos": "99" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "104", "end_pos": "104" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "33", "end_pos": "33" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P25293-1.11.11", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P25293-1.12.12", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P25293-1.20.20", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P25293-1.24.24", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P25293-1.32.32", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P25293-1.33.33", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 14 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25293-1.2.2", "start_pos": 2, "end_pos": 2, "uniprot_canonical_ac": "P25293-1", "length": 417, "uniprot_id": "NAP1_YEAST", "protein_name": "Nucleosome assembly protein", "refseq_ac": "NP_012974", "refseq_name": "histone chaperone NAP1", "gene_name": "NAP1", "gene_names_uniprotkb": "NAP1", "gene_names_refseq": "NAP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000001756", "url": "https://www.yeastgenome.org/locus/S000001756", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "M", "down_seq": "DPIRTKPKSSMQIDNAPTPH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000001756", "url": "https://www.yeastgenome.org/locus/S000001756" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser2" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "288", "end_pos": "292" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "290", "end_pos": "305" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "99", "end_pos": "99" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "104", "end_pos": "104" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "33", "end_pos": "33" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "upstream", "id": "P25293-1.11.11", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P25293-1.12.12", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P25293-1.20.20", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25293-1.32.32", "start_pos": 32, "end_pos": 32, "uniprot_canonical_ac": "P25293-1", "length": 417, "uniprot_id": "NAP1_YEAST", "protein_name": "Nucleosome assembly protein", "refseq_ac": "NP_012974", "refseq_name": "histone chaperone NAP1", "gene_name": "NAP1", "gene_names_uniprotkb": "NAP1", "gene_names_refseq": "NAP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000001756", "url": "https://www.yeastgenome.org/locus/S000001756", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SMQIDNAPTPHNTPASVLNP", "down_seq": "YLKNGNPVRAQAQEQDDKIG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000001756", "url": "https://www.yeastgenome.org/locus/S000001756" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser32" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "288", "end_pos": "292" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "290", "end_pos": "305" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "99", "end_pos": "99" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "104", "end_pos": "104" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "33", "end_pos": "33" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P25293-1.12.12", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P25293-1.20.20", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P25293-1.24.24", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P25293-1.27.27", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P25293-1.33.33", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25293-1.33.33", "start_pos": 33, "end_pos": 33, "uniprot_canonical_ac": "P25293-1", "length": 417, "uniprot_id": "NAP1_YEAST", "protein_name": "Nucleosome assembly protein", "refseq_ac": "NP_012974", "refseq_name": "histone chaperone NAP1", "gene_name": "NAP1", "gene_names_uniprotkb": "NAP1", "gene_names_refseq": "NAP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ], "crossref": [ { "id": "S000001756", "url": "https://www.yeastgenome.org/locus/S000001756", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "MQIDNAPTPHNTPASVLNPS", "down_seq": "LKNGNPVRAQAQEQDDKIGT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000001756", "url": "https://www.yeastgenome.org/locus/S000001756" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ], "site_lbl": "Tyr33" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "288", "end_pos": "292" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "290", "end_pos": "305" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "99", "end_pos": "99" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "104", "end_pos": "104" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "33", "end_pos": "33" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P25293-1.20.20", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P25293-1.24.24", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P25293-1.27.27", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P25293-1.32.32", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P25293-1.53.53", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25293-1.53.53", "start_pos": 53, "end_pos": 53, "uniprot_canonical_ac": "P25293-1", "length": 417, "uniprot_id": "NAP1_YEAST", "protein_name": "Nucleosome assembly protein", "refseq_ac": "NP_012974", "refseq_name": "histone chaperone NAP1", "gene_name": "NAP1", "gene_names_uniprotkb": "NAP1", "gene_names_refseq": "NAP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000001756", "url": "https://www.yeastgenome.org/locus/S000001756", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "YLKNGNPVRAQAQEQDDKIG", "down_seq": "INEEDILANQPLLLQSIQDR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000001756", "url": "https://www.yeastgenome.org/locus/S000001756" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr53" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "288", "end_pos": "292" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "290", "end_pos": "305" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "99", "end_pos": "99" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "104", "end_pos": "104" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "33", "end_pos": "33" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P25293-1.33.33", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P25293-1.69.69", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25293-1.69.69", "start_pos": 69, "end_pos": 69, "uniprot_canonical_ac": "P25293-1", "length": 417, "uniprot_id": "NAP1_YEAST", "protein_name": "Nucleosome assembly protein", "refseq_ac": "NP_012974", "refseq_name": "histone chaperone NAP1", "gene_name": "NAP1", "gene_names_uniprotkb": "NAP1", "gene_names_refseq": "NAP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000001756", "url": "https://www.yeastgenome.org/locus/S000001756", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DKIGTINEEDILANQPLLLQ", "down_seq": "IQDRLGSLVGQDSGYVGGLP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" }, { "database": "SGD", "id": "S000001756", "url": "https://www.yeastgenome.org/locus/S000001756" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser69" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "288", "end_pos": "292" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "290", "end_pos": "305" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "99", "end_pos": "99" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "104", "end_pos": "104" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "33", "end_pos": "33" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P25293-1.53.53", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P25293-1.76.76", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P25293-1.82.82", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P25293-1.84.84", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25293-1.76.76", "start_pos": 76, "end_pos": 76, "uniprot_canonical_ac": "P25293-1", "length": 417, "uniprot_id": "NAP1_YEAST", "protein_name": "Nucleosome assembly protein", "refseq_ac": "NP_012974", "refseq_name": "histone chaperone NAP1", "gene_name": "NAP1", "gene_names_uniprotkb": "NAP1", "gene_names_refseq": "NAP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.", "journal": "Molecular & cellular proteomics : MCP", "date": "2005-03", "authors": "Gruhler Albrecht, Olsen Jesper V, Mohammed Shabaz, Mortensen Peter, Faergeman Nils J, Mann Matthias, Jensen Ole N", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "Journal of proteome research", "date": "2007-03", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] }, { "title": "Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast.", "journal": "Science signaling", "date": "2010-12-21", "authors": "Bodenmiller Bernd, Wanka Stefanie, Kraft Claudine, Urban J\u00f6rg, Campbell David, Pedrioli Patrick G, Gerrits Bertran, Picotti Paola, Lam Henry, Vitek Olga, Brusniak Mi-Youn, Roschitzki Bernd, Zhang Chao, Shokat Kevan M, Schlapbach Ralph, Colman-Lerner Alejandro, Nolan Garry P, Nesvizhskii Alexey I, Peter Matthias, Loewith Robbie, von Mering Christian, Aebersold Ruedi", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "title": "Global mapping of protein phosphorylation events identifies Ste20, Sch9 and the cell-cycle regulatory kinases Cdc28/Pho85 as mediators of fatty acid starvation responses in Saccharomyces cerevisiae.", "journal": "Molecular bioSystems", "date": "2012-03", "authors": "Pultz Dennis, Bennetzen Martin V, R\u00f8dk\u00e6r Steven Vestergaard, Zimmermann Christine, Enserink Jorrit M, Andersen Jens S, F\u00e6rgeman Nils J", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000001756", "url": "https://www.yeastgenome.org/locus/S000001756", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EEDILANQPLLLQSIQDRLG", "down_seq": "LVGQDSGYVGGLPKNVKEKL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000001756", "url": "https://www.yeastgenome.org/locus/S000001756" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser76" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "288", "end_pos": "292" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "290", "end_pos": "305" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "99", "end_pos": "99" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "104", "end_pos": "104" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "33", "end_pos": "33" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P25293-1.69.69", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P25293-1.82.82", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P25293-1.84.84", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 13 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25293-1.82.82", "start_pos": 82, "end_pos": 82, "uniprot_canonical_ac": "P25293-1", "length": 417, "uniprot_id": "NAP1_YEAST", "protein_name": "Nucleosome assembly protein", "refseq_ac": "NP_012974", "refseq_name": "histone chaperone NAP1", "gene_name": "NAP1", "gene_names_uniprotkb": "NAP1", "gene_names_refseq": "NAP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphorylation by casein kinase 2 regulates Nap1 localization and function.", "journal": "Molecular and cellular biology", "date": "2008-02", "authors": "Calvert Meredith E K, Keck Kristin M, Ptak Celeste, Shabanowitz Jeffrey, Hunt Donald F, Pemberton Lucy F", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global mapping of protein phosphorylation events identifies Ste20, Sch9 and the cell-cycle regulatory kinases Cdc28/Pho85 as mediators of fatty acid starvation responses in Saccharomyces cerevisiae.", "journal": "Molecular bioSystems", "date": "2012-03", "authors": "Pultz Dennis, Bennetzen Martin V, R\u00f8dk\u00e6r Steven Vestergaard, Zimmermann Christine, Enserink Jorrit M, Andersen Jens S, F\u00e6rgeman Nils J", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Glucose intake hampers PKA-regulated HSP90 chaperone activity.", "journal": "eLife", "date": "2018-12-05", "authors": "Chen Yu-Chen, Jiang Pei-Heng, Chen Hsuan-Ming, Chen Chang-Han, Wang Yi-Ting, Chen Yu-Ju, Yu Chia-Jung, Teng Shu-Chun", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000001756", "url": "https://www.yeastgenome.org/locus/S000001756", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NQPLLLQSIQDRLGSLVGQD", "down_seq": "GYVGGLPKNVKEKLLSLKTL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "PubMed", "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000001756", "url": "https://www.yeastgenome.org/locus/S000001756" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser82" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "288", "end_pos": "292" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "290", "end_pos": "305" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "99", "end_pos": "99" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "104", "end_pos": "104" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "33", "end_pos": "33" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P25293-1.69.69", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P25293-1.76.76", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P25293-1.84.84", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P25293-1.98.98", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P25293-1.99.99", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25293-1.84.84", "start_pos": 84, "end_pos": 84, "uniprot_canonical_ac": "P25293-1", "length": 417, "uniprot_id": "NAP1_YEAST", "protein_name": "Nucleosome assembly protein", "refseq_ac": "NP_012974", "refseq_name": "histone chaperone NAP1", "gene_name": "NAP1", "gene_names_uniprotkb": "NAP1", "gene_names_refseq": "NAP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000001756", "url": "https://www.yeastgenome.org/locus/S000001756", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "PLLLQSIQDRLGSLVGQDSG", "down_seq": "VGGLPKNVKEKLLSLKTLQS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000001756", "url": "https://www.yeastgenome.org/locus/S000001756" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Tyr84" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "288", "end_pos": "292" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "290", "end_pos": "305" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "99", "end_pos": "99" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "104", "end_pos": "104" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "33", "end_pos": "33" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P25293-1.69.69", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P25293-1.76.76", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P25293-1.82.82", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P25293-1.98.98", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P25293-1.99.99", "categories": [ "mutagenesis_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P25293-1.104.104", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25293-1.98.98", "start_pos": 98, "end_pos": 98, "uniprot_canonical_ac": "P25293-1", "length": 417, "uniprot_id": "NAP1_YEAST", "protein_name": "Nucleosome assembly protein", "refseq_ac": "NP_012974", "refseq_name": "histone chaperone NAP1", "gene_name": "NAP1", "gene_names_uniprotkb": "NAP1", "gene_names_refseq": "NAP1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphorylation by casein kinase 2 regulates Nap1 localization and function.", "journal": "Molecular and cellular biology", "date": "2008-02", "authors": "Calvert Meredith E K, Keck Kristin M, Ptak Celeste, Shabanowitz Jeffrey, Hunt Donald F, Pemberton Lucy F", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "reference": [ { "type": "PubMed", "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883" } ] } ], "crossref": [ { "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VGQDSGYVGGLPKNVKEKLL", "down_seq": "LKTLQSELFEVEKEFQVEMF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P25293", "url": "https://www.uniprot.org/uniprotkb/P25293" }, { "database": "PubMed", "id": "18086883", "url": "https://glygen.org/publication/PubMed/18086883" }, { "database": "iPTMnet", "id": "P25293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25293" } ], "site_lbl": "Ser98" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "288", "end_pos": "292" }, { "start_pos": "290", "end_pos": "290" }, { "start_pos": "290", "end_pos": "305" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "99", "end_pos": "99" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "104", "end_pos": "104" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "33", "end_pos": "33" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "76", "end_pos": "76" }, { "start_pos": "82", "end_pos": "82" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P25293-1.82.82", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P25293-1.84.84", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P25293-1.99.99", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P25293-1.104.104", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25294-1.107.107", "start_pos": 107, "end_pos": 107, "uniprot_canonical_ac": "P25294-1", "length": 352, "uniprot_id": "SIS1_YEAST", "protein_name": "Protein SIS1", "refseq_ac": "NP_014391", "refseq_name": "type II HSP40 co-chaperone SIS1", "gene_name": "SIS1", "gene_names_uniprotkb": "SIS1; N2879", "gene_names_refseq": "SIS1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25294", "url": "https://www.uniprot.org/uniprotkb/P25294" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004952", "url": "https://www.yeastgenome.org/locus/S000004952", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AGGAGGFPGGAGGFSGGHAF", "down_seq": "NEDAFNIFSQFFGGSSPFGG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004952", "url": "https://www.yeastgenome.org/locus/S000004952" }, { "database": "iPTMnet", "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser107" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "175", "end_pos": "175" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "339", "end_pos": "339" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25294-1.14.14", "start_pos": 14, "end_pos": 14, "uniprot_canonical_ac": "P25294-1", "length": 352, "uniprot_id": "SIS1_YEAST", "protein_name": "Protein SIS1", "refseq_ac": "NP_014391", "refseq_name": "type II HSP40 co-chaperone SIS1", "gene_name": "SIS1", "gene_names_uniprotkb": "SIS1; N2879", "gene_names_refseq": "SIS1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25294", "url": "https://www.uniprot.org/uniprotkb/P25294" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Mol. Cell. Proteomics", "date": "2008", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P25294", "url": "https://www.uniprot.org/uniprotkb/P25294" }, { "database": "iPTMnet", "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004952", "url": "https://www.yeastgenome.org/locus/S000004952", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MVKETKLYDLLGV", "down_seq": "PSANEQELKKGYRKAALKYH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004952", "url": "https://www.yeastgenome.org/locus/S000004952" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser14" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "175", "end_pos": "175" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "339", "end_pos": "339" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25294-1.169.169", "start_pos": 169, "end_pos": 169, "uniprot_canonical_ac": "P25294-1", "length": 352, "uniprot_id": "SIS1_YEAST", "protein_name": "Protein SIS1", "refseq_ac": "NP_014391", "refseq_name": "type II HSP40 co-chaperone SIS1", "gene_name": "SIS1", "gene_names_uniprotkb": "SIS1; N2879", "gene_names_refseq": "SIS1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25294", "url": "https://www.uniprot.org/uniprotkb/P25294" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P25294", "url": "https://www.uniprot.org/uniprotkb/P25294" }, { "database": "iPTMnet", "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] } ], "crossref": [ { "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004952", "url": "https://www.yeastgenome.org/locus/S000004952", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MPGGMGGMHGGMGGMPGGFR", "down_seq": "ASSSPTYPEEETVQVNLPVS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004952", "url": "https://www.yeastgenome.org/locus/S000004952" } ], "site_lbl": "Ser169" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "175", "end_pos": "175" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "339", "end_pos": "339" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P25294-1.171.171", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P25294-1.172.172", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P25294-1.173.173", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P25294-1.175.175", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25294-1.171.171", "start_pos": 171, "end_pos": 171, "uniprot_canonical_ac": "P25294-1", "length": 352, "uniprot_id": "SIS1_YEAST", "protein_name": "Protein SIS1", "refseq_ac": "NP_014391", "refseq_name": "type II HSP40 co-chaperone SIS1", "gene_name": "SIS1", "gene_names_uniprotkb": "SIS1; N2879", "gene_names_refseq": "SIS1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25294", "url": "https://www.uniprot.org/uniprotkb/P25294" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P25294", "url": "https://www.uniprot.org/uniprotkb/P25294" }, { "database": "iPTMnet", "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] } ], "crossref": [ { "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004952", "url": "https://www.yeastgenome.org/locus/S000004952", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GGMGGMHGGMGGMPGGFRSA", "down_seq": "SSPTYPEEETVQVNLPVSLE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004952", "url": "https://www.yeastgenome.org/locus/S000004952" } ], "site_lbl": "Ser171" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "175", "end_pos": "175" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "339", "end_pos": "339" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P25294-1.169.169", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P25294-1.172.172", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P25294-1.173.173", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P25294-1.175.175", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25294-1.172.172", "start_pos": 172, "end_pos": 172, "uniprot_canonical_ac": "P25294-1", "length": 352, "uniprot_id": "SIS1_YEAST", "protein_name": "Protein SIS1", "refseq_ac": "NP_014391", "refseq_name": "type II HSP40 co-chaperone SIS1", "gene_name": "SIS1", "gene_names_uniprotkb": "SIS1; N2879", "gene_names_refseq": "SIS1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25294", "url": "https://www.uniprot.org/uniprotkb/P25294" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004952", "url": "https://www.yeastgenome.org/locus/S000004952", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GMGGMHGGMGGMPGGFRSAS", "down_seq": "SPTYPEEETVQVNLPVSLED", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004952", "url": "https://www.yeastgenome.org/locus/S000004952" }, { "database": "iPTMnet", "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser172" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "175", "end_pos": "175" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "339", "end_pos": "339" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P25294-1.169.169", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P25294-1.171.171", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P25294-1.173.173", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P25294-1.175.175", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25294-1.173.173", "start_pos": 173, "end_pos": 173, "uniprot_canonical_ac": "P25294-1", "length": 352, "uniprot_id": "SIS1_YEAST", "protein_name": "Protein SIS1", "refseq_ac": "NP_014391", "refseq_name": "type II HSP40 co-chaperone SIS1", "gene_name": "SIS1", "gene_names_uniprotkb": "SIS1; N2879", "gene_names_refseq": "SIS1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25294", "url": "https://www.uniprot.org/uniprotkb/P25294" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.", "journal": "Molecular & cellular proteomics : MCP", "date": "2005-03", "authors": "Gruhler Albrecht, Olsen Jesper V, Mohammed Shabaz, Mortensen Peter, Faergeman Nils J, Mann Matthias, Jensen Ole N", "evidence": [ { "database": "iPTMnet", "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294" } ], "reference": [ { "type": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Mol. Cell. Proteomics", "date": "2008", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P25294", "url": "https://www.uniprot.org/uniprotkb/P25294" }, { "database": "iPTMnet", "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ], "crossref": [ { "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004952", "url": "https://www.yeastgenome.org/locus/S000004952", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MGGMHGGMGGMPGGFRSASS", "down_seq": "PTYPEEETVQVNLPVSLEDL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "SGD", "id": "S000004952", "url": "https://www.yeastgenome.org/locus/S000004952" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ], "site_lbl": "Ser173" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "175", "end_pos": "175" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "339", "end_pos": "339" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P25294-1.169.169", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P25294-1.171.171", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P25294-1.172.172", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P25294-1.175.175", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25294-1.175.175", "start_pos": 175, "end_pos": 175, "uniprot_canonical_ac": "P25294-1", "length": 352, "uniprot_id": "SIS1_YEAST", "protein_name": "Protein SIS1", "refseq_ac": "NP_014391", "refseq_name": "type II HSP40 co-chaperone SIS1", "gene_name": "SIS1", "gene_names_uniprotkb": "SIS1; N2879", "gene_names_refseq": "SIS1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25294", "url": "https://www.uniprot.org/uniprotkb/P25294" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P25294", "url": "https://www.uniprot.org/uniprotkb/P25294" }, { "database": "iPTMnet", "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] } ], "crossref": [ { "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004952", "url": "https://www.yeastgenome.org/locus/S000004952", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "GMHGGMGGMPGGFRSASSSP", "down_seq": "YPEEETVQVNLPVSLEDLFV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004952", "url": "https://www.yeastgenome.org/locus/S000004952" } ], "site_lbl": "Thr175" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "175", "end_pos": "175" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "339", "end_pos": "339" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "P25294-1.169.169", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P25294-1.171.171", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P25294-1.172.172", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P25294-1.173.173", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25294-1.248.248", "start_pos": 248, "end_pos": 248, "uniprot_canonical_ac": "P25294-1", "length": 352, "uniprot_id": "SIS1_YEAST", "protein_name": "Protein SIS1", "refseq_ac": "NP_014391", "refseq_name": "type II HSP40 co-chaperone SIS1", "gene_name": "SIS1", "gene_names_uniprotkb": "SIS1; N2879", "gene_names_refseq": "SIS1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25294", "url": "https://www.uniprot.org/uniprotkb/P25294" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004952", "url": "https://www.yeastgenome.org/locus/S000004952", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "GTKITYKNQGDYNPQTGRRK", "down_seq": "LQFVIQEKSHPNFKRDGDDL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000004952", "url": "https://www.yeastgenome.org/locus/S000004952" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr248" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "175", "end_pos": "175" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "339", "end_pos": "339" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25294-1.275.275", "start_pos": 275, "end_pos": 275, "uniprot_canonical_ac": "P25294-1", "length": 352, "uniprot_id": "SIS1_YEAST", "protein_name": "Protein SIS1", "refseq_ac": "NP_014391", "refseq_name": "type II HSP40 co-chaperone SIS1", "gene_name": "SIS1", "gene_names_uniprotkb": "SIS1; N2879", "gene_names_refseq": "SIS1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25294", "url": "https://www.uniprot.org/uniprotkb/P25294" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P25294", "url": "https://www.uniprot.org/uniprotkb/P25294" }, { "database": "iPTMnet", "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P25294", "url": "https://www.uniprot.org/uniprotkb/P25294", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004952", "url": "https://www.yeastgenome.org/locus/S000004952", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EKSHPNFKRDGDDLIYTLPL", "down_seq": "FKESLLGFSKTIQTIDGRTL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P25294", "url": "https://www.uniprot.org/uniprotkb/P25294" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000004952", "url": "https://www.yeastgenome.org/locus/S000004952" }, { "database": "iPTMnet", "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser275" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "175", "end_pos": "175" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "339", "end_pos": "339" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "upstream", "id": "P25294-1.284.284", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25294-1.284.284", "start_pos": 284, "end_pos": 284, "uniprot_canonical_ac": "P25294-1", "length": 352, "uniprot_id": "SIS1_YEAST", "protein_name": "Protein SIS1", "refseq_ac": "NP_014391", "refseq_name": "type II HSP40 co-chaperone SIS1", "gene_name": "SIS1", "gene_names_uniprotkb": "SIS1; N2879", "gene_names_refseq": "SIS1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25294", "url": "https://www.uniprot.org/uniprotkb/P25294" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004952", "url": "https://www.yeastgenome.org/locus/S000004952", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DGDDLIYTLPLSFKESLLGF", "down_seq": "KTIQTIDGRTLPLSRVQPVQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004952", "url": "https://www.yeastgenome.org/locus/S000004952" }, { "database": "iPTMnet", "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser284" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "175", "end_pos": "175" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "339", "end_pos": "339" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "P25294-1.275.275", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25294-1.318.318", "start_pos": 318, "end_pos": 318, "uniprot_canonical_ac": "P25294-1", "length": 352, "uniprot_id": "SIS1_YEAST", "protein_name": "Protein SIS1", "refseq_ac": "NP_014391", "refseq_name": "type II HSP40 co-chaperone SIS1", "gene_name": "SIS1", "gene_names_uniprotkb": "SIS1; N2879", "gene_names_refseq": "SIS1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25294", "url": "https://www.uniprot.org/uniprotkb/P25294" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "crossref": [ { "id": "S000004952", "url": "https://www.yeastgenome.org/locus/S000004952", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SRVQPVQPSQTSTYPGQGMP", "down_seq": "PKNPSQRGNLIVKYKVDYPI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004952", "url": "https://www.yeastgenome.org/locus/S000004952" }, { "database": "iPTMnet", "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Thr318" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "175", "end_pos": "175" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "339", "end_pos": "339" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25294-1.339.339", "start_pos": 339, "end_pos": 339, "uniprot_canonical_ac": "P25294-1", "length": 352, "uniprot_id": "SIS1_YEAST", "protein_name": "Protein SIS1", "refseq_ac": "NP_014391", "refseq_name": "type II HSP40 co-chaperone SIS1", "gene_name": "SIS1", "gene_names_uniprotkb": "SIS1; N2879", "gene_names_refseq": "SIS1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25294", "url": "https://www.uniprot.org/uniprotkb/P25294" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004952", "url": "https://www.yeastgenome.org/locus/S000004952", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PKNPSQRGNLIVKYKVDYPI", "down_seq": "LNDAQKRAIDENF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004952", "url": "https://www.yeastgenome.org/locus/S000004952" }, { "database": "iPTMnet", "id": "P25294", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25294" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser339" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "14", "end_pos": "14" }, { "start_pos": "169", "end_pos": "169" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "175", "end_pos": "175" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "339", "end_pos": "339" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.23.23", "start_pos": 23, "end_pos": 23, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P25302", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P25302" }, { "database": "O-GlcNAc Atlas", "id": "P25302", "url": "https://oglcnac.org/atlas/detail/P25302" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P25302", "url": "https://oglcnac.org/atlas/detail/P25302", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FDVLISNQKDNTNHQNITPI", "down_seq": "KSVLLAPHSNHPVIEIATYS", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser23", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P25302", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P25302" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser23" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P25302-1.8.8", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P25302-1.20.20", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.456.456", "start_pos": 456, "end_pos": 456, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P25302", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P25302" }, { "database": "O-GlcNAc Atlas", "id": "P25302", "url": "https://oglcnac.org/atlas/detail/P25302" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P25302", "url": "https://oglcnac.org/atlas/detail/P25302", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SSIEVFSSNENDNSMNMSSR", "down_seq": "MTPFSAGNTSSQNKLENKMT", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser456", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P25302", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P25302" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P25302-1.458.458", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P25302-1.461.461", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P25302-1.466.466", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P25302-1.467.467", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.458.458", "start_pos": 458, "end_pos": 458, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P25302", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P25302" }, { "database": "O-GlcNAc Atlas", "id": "P25302", "url": "https://oglcnac.org/atlas/detail/P25302" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P25302", "url": "https://oglcnac.org/atlas/detail/P25302", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "IEVFSSNENDNSMNMSSRSM", "down_seq": "PFSAGNTSSQNKLENKMTDQ", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr458", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P25302", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P25302" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr458" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P25302-1.456.456", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P25302-1.461.461", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P25302-1.466.466", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P25302-1.467.467", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.461.461", "start_pos": 461, "end_pos": 461, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P25302", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P25302" }, { "database": "O-GlcNAc Atlas", "id": "P25302", "url": "https://oglcnac.org/atlas/detail/P25302" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P25302", "url": "https://oglcnac.org/atlas/detail/P25302", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FSSNENDNSMNMSSRSMTPF", "down_seq": "AGNTSSQNKLENKMTDQEYK", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser461", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P25302", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P25302" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "P25302-1.456.456", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P25302-1.458.458", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P25302-1.466.466", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P25302-1.467.467", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.466.466", "start_pos": 466, "end_pos": 466, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P25302", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P25302" }, { "database": "O-GlcNAc Atlas", "id": "P25302", "url": "https://oglcnac.org/atlas/detail/P25302" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P25302", "url": "https://oglcnac.org/atlas/detail/P25302", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NDNSMNMSSRSMTPFSAGNT", "down_seq": "SQNKLENKMTDQEYKQTILT", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser466", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P25302", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P25302" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser466" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "P25302-1.456.456", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P25302-1.458.458", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P25302-1.461.461", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P25302-1.467.467", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.467.467", "start_pos": 467, "end_pos": 467, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P25302", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P25302" }, { "database": "O-GlcNAc Atlas", "id": "P25302", "url": "https://oglcnac.org/atlas/detail/P25302" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P25302", "url": "https://oglcnac.org/atlas/detail/P25302", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DNSMNMSSRSMTPFSAGNTS", "down_seq": "QNKLENKMTDQEYKQTILTI", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser467", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P25302", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P25302" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P25302-1.456.456", "categories": [ "glycosylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P25302-1.458.458", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P25302-1.461.461", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P25302-1.466.466", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P25302", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P25302" }, { "database": "O-GlcNAc Atlas", "id": "P25302", "url": "https://oglcnac.org/atlas/detail/P25302" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P25302", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P25302", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P25302", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P25302" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "upstream", "id": "P25302-1.8.8", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P25302-1.20.20", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.1003.1003", "start_pos": 1003, "end_pos": 1003, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae.", "journal": "Nature biotechnology", "date": "2002-03", "authors": "Ficarro Scott B, McCleland Mark L, Stukenberg P Todd, Burke Daniel J, Ross Mark M, Shabanowitz Jeffrey, Hunt Donald F, White Forest M", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TNSSSHPEKQEDEEPIPKST", "down_seq": "ETSSPKNTKADAKFSNTVQE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1003" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P25302-1.1005.1005", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P25302-1.1006.1006", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P25302-1.1007.1007", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P25302-1.1011.1011", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.1005.1005", "start_pos": 1005, "end_pos": 1005, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SSSHPEKQEDEEPIPKSTSE", "down_seq": "SSPKNTKADAKFSNTVQESY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr1005" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P25302-1.1003.1003", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P25302-1.1006.1006", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P25302-1.1007.1007", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P25302-1.1011.1011", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.1006.1006", "start_pos": 1006, "end_pos": 1006, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SSHPEKQEDEEPIPKSTSET", "down_seq": "SPKNTKADAKFSNTVQESYD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1006" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P25302-1.1003.1003", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P25302-1.1005.1005", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P25302-1.1007.1007", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P25302-1.1011.1011", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.1007.1007", "start_pos": 1007, "end_pos": 1007, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae.", "journal": "Nature biotechnology", "date": "2002-03", "authors": "Ficarro Scott B, McCleland Mark L, Stukenberg P Todd, Burke Daniel J, Ross Mark M, Shabanowitz Jeffrey, Hunt Donald F, White Forest M", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SHPEKQEDEEPIPKSTSETS", "down_seq": "PKNTKADAKFSNTVQESYDV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1007" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P25302-1.1003.1003", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P25302-1.1005.1005", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P25302-1.1006.1006", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P25302-1.1011.1011", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.1011.1011", "start_pos": 1011, "end_pos": 1011, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ], "crossref": [ { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "KQEDEEPIPKSTSETSSPKN", "down_seq": "KADAKFSNTVQESYDVNETL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ], "site_lbl": "Thr1011" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "P25302-1.1003.1003", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P25302-1.1005.1005", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P25302-1.1006.1006", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P25302-1.1007.1007", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.1060.1060", "start_pos": 1060, "end_pos": 1060, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LQFKRRMTTLKISEAKSKIN", "down_seq": "SVKLDKYRNLIGITIENIDS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser1060" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "P25302-1.1061.1061", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.1061.1061", "start_pos": 1061, "end_pos": 1061, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QFKRRMTTLKISEAKSKINS", "down_seq": "VKLDKYRNLIGITIENIDSK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser1061" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "P25302-1.1060.1060", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.158.158", "start_pos": 158, "end_pos": 158, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cell cycle phosphorylation of mitotic exit network (MEN) proteins.", "journal": "Cell cycle (Georgetown, Tex.)", "date": "2011-10-15", "authors": "Jones Michele H, Keck Jamie M, Wong Catherine C L, Xu Tao, Yates John R, Winey Mark", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "22031224", "url": "https://glygen.org/publication/PubMed/22031224" } ] } ], "crossref": [ { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "22031224", "url": "https://glygen.org/publication/PubMed/22031224", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "FQFDPNNPPPKRSKNSILRK", "down_seq": "SPGTKITSPSSYNKTPRKKN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "22031224", "url": "https://glygen.org/publication/PubMed/22031224" } ], "site_lbl": "Thr158" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "P25302-1.159.159", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P25302-1.165.165", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P25302-1.166.166", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P25302-1.173.173", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.159.159", "start_pos": 159, "end_pos": 159, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2007", "authors": "Chi An, Huttenhower Curtis, Geer Lewis Y, Coon Joshua J, Syka John E P, Bai Dina L, Shabanowitz Jeffrey, Burke Daniel J, Troyanskaya Olga G, Hunt Donald F", "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QFDPNNPPPKRSKNSILRKT", "down_seq": "PGTKITSPSSYNKTPRKKNS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser159" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "P25302-1.158.158", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P25302-1.165.165", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P25302-1.166.166", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P25302-1.173.173", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.165.165", "start_pos": 165, "end_pos": 165, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ], "crossref": [ { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PPPKRSKNSILRKTSPGTKI", "down_seq": "SPSSYNKTPRKKNSSSSTSA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ], "site_lbl": "Thr165" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P25302-1.158.158", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P25302-1.159.159", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P25302-1.166.166", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P25302-1.173.173", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P25302-1.180.180", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P25302-1.184.184", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.166.166", "start_pos": 166, "end_pos": 166, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.", "journal": "Genes & development", "date": "2009-08-15", "authors": "Huber Alexandre, Bodenmiller Bernd, Uotila Aino, Stahl Michael, Wanka Stefanie, Gerrits Bertran, Aebersold Ruedi, Loewith Robbie", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] }, { "title": "Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast.", "journal": "Science signaling", "date": "2010-12-21", "authors": "Bodenmiller Bernd, Wanka Stefanie, Kraft Claudine, Urban J\u00f6rg, Campbell David, Pedrioli Patrick G, Gerrits Bertran, Picotti Paola, Lam Henry, Vitek Olga, Brusniak Mi-Youn, Roschitzki Bernd, Zhang Chao, Shokat Kevan M, Schlapbach Ralph, Colman-Lerner Alejandro, Nolan Garry P, Nesvizhskii Alexey I, Peter Matthias, Loewith Robbie, von Mering Christian, Aebersold Ruedi", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PPKRSKNSILRKTSPGTKIT", "down_seq": "PSSYNKTPRKKNSSSSTSAT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser166" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "P25302-1.158.158", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P25302-1.159.159", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P25302-1.165.165", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P25302-1.173.173", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P25302-1.180.180", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P25302-1.184.184", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.173.173", "start_pos": 173, "end_pos": 173, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.", "journal": "Genes & development", "date": "2009-08-15", "authors": "Huber Alexandre, Bodenmiller Bernd, Uotila Aino, Stahl Michael, Wanka Stefanie, Gerrits Bertran, Aebersold Ruedi, Loewith Robbie", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] }, { "title": "Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast.", "journal": "Science signaling", "date": "2010-12-21", "authors": "Bodenmiller Bernd, Wanka Stefanie, Kraft Claudine, Urban J\u00f6rg, Campbell David, Pedrioli Patrick G, Gerrits Bertran, Picotti Paola, Lam Henry, Vitek Olga, Brusniak Mi-Youn, Roschitzki Bernd, Zhang Chao, Shokat Kevan M, Schlapbach Ralph, Colman-Lerner Alejandro, Nolan Garry P, Nesvizhskii Alexey I, Peter Matthias, Loewith Robbie, von Mering Christian, Aebersold Ruedi", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SILRKTSPGTKITSPSSYNK", "down_seq": "PRKKNSSSSTSATTTAANKK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr173" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P25302-1.158.158", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P25302-1.159.159", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P25302-1.165.165", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P25302-1.166.166", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P25302-1.180.180", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P25302-1.184.184", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P25302-1.187.187", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P25302-1.188.188", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.180.180", "start_pos": 180, "end_pos": 180, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PGTKITSPSSYNKTPRKKNS", "down_seq": "SSTSATTTAANKKGKKNASI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser180" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P25302-1.165.165", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P25302-1.166.166", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P25302-1.173.173", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P25302-1.184.184", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P25302-1.187.187", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P25302-1.188.188", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.184.184", "start_pos": 184, "end_pos": 184, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ITSPSSYNKTPRKKNSSSST", "down_seq": "ATTTAANKKGKKNASINQPN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser184" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P25302-1.165.165", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "downstream", "id": "P25302-1.166.166", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P25302-1.173.173", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P25302-1.180.180", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P25302-1.187.187", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P25302-1.188.188", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.187.187", "start_pos": 187, "end_pos": 187, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cell cycle phosphorylation of mitotic exit network (MEN) proteins.", "journal": "Cell cycle (Georgetown, Tex.)", "date": "2011-10-15", "authors": "Jones Michele H, Keck Jamie M, Wong Catherine C L, Xu Tao, Yates John R, Winey Mark", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "22031224", "url": "https://glygen.org/publication/PubMed/22031224" } ] } ], "crossref": [ { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "22031224", "url": "https://glygen.org/publication/PubMed/22031224", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PSSYNKTPRKKNSSSSTSAT", "down_seq": "TAANKKGKKNASINQPNPSP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "22031224", "url": "https://glygen.org/publication/PubMed/22031224" } ], "site_lbl": "Thr187" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "P25302-1.173.173", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P25302-1.180.180", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P25302-1.184.184", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P25302-1.188.188", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P25302-1.206.206", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.188.188", "start_pos": 188, "end_pos": 188, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SSYNKTPRKKNSSSSTSATT", "down_seq": "AANKKGKKNASINQPNPSPL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr188" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P25302-1.173.173", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P25302-1.180.180", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P25302-1.184.184", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P25302-1.187.187", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P25302-1.206.206", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.206.206", "start_pos": 206, "end_pos": 206, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TTTAANKKGKKNASINQPNP", "down_seq": "PLQNLVFQTPQQFQVNSSMN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser206" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P25302-1.187.187", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "downstream", "id": "P25302-1.188.188", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.20.20", "start_pos": 20, "end_pos": 20, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast.", "journal": "Proteomics", "date": "2009-10", "authors": "Gnad Florian, de Godoy Lyris M F, Cox J\u00fcrgen, Neuhauser Nadin, Ren Shubin, Olsen Jesper V, Mann Matthias", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" } ] }, { "title": "Global analysis of the yeast osmotic stress response by quantitative proteomics.", "journal": "Molecular bioSystems", "date": "2009-11", "authors": "Soufi Boumediene, Kelstrup Christian D, Stoehr Gabriele, Fr\u00f6hlich Florian, Walther Tobias C, Olsen Jesper V", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "", "down_seq": "PISKSVLLAPHSNHPVIEIA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr20" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P25302-1.0.0", "categories": [ "glycosylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P25302-1.8.8", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P25302-1.23.23", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 7 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.255.255", "start_pos": 255, "end_pos": 255, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TTMNFNNDTRHNLINNISNN", "down_seq": "NQSTIIQQQKSIHENSFNNN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser255" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "upstream", "id": "P25302-1.271.271", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.271.271", "start_pos": 271, "end_pos": 271, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ISNNSNQSTIIQQQKSIHEN", "down_seq": "FNNNYSATQKPLQFFPIPTN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser271" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P25302-1.255.255", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.687.687", "start_pos": 687, "end_pos": 687, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "STDILNLDNESPASIMNKFN", "down_seq": "PAGGSNSRNNNTKADRKLAR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr687" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "upstream", "id": "P25302-1.692.692", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P25302-1.694.694", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.692.692", "start_pos": 692, "end_pos": 692, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NLDNESPASIMNKFNTPAGG", "down_seq": "NSRNNNTKADRKLARNLPQK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser692" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "P25302-1.687.687", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P25302-1.694.694", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.694.694", "start_pos": 694, "end_pos": 694, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DNESPASIMNKFNTPAGGSN", "down_seq": "RNNNTKADRKLARNLPQKNY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser694" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P25302-1.687.687", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P25302-1.692.692", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.744.744", "start_pos": 744, "end_pos": 744, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PQNNVKIPKIIKTQHPDKED", "down_seq": "TADVNIAKTDSEVNESQYLH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser744" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.798.798", "start_pos": 798, "end_pos": 798, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "EDLSNINSFVTSSVIKDIKS", "down_seq": "PSKILENSPILYRRRSQSIS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr798" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "upstream", "id": "P25302-1.806.806", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P25302-1.810.810", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P25302-1.814.814", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P25302-1.816.816", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.806.806", "start_pos": 806, "end_pos": 806, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.", "journal": "Molecular & cellular proteomics : MCP", "date": "2005-03", "authors": "Gruhler Albrecht, Olsen Jesper V, Mohammed Shabaz, Mortensen Peter, Faergeman Nils J, Mann Matthias, Jensen Ole N", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FVTSSVIKDIKSTPSKILEN", "down_seq": "PILYRRRSQSISDEKEKAKD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser806" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "P25302-1.798.798", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P25302-1.810.810", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P25302-1.814.814", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P25302-1.816.816", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 9 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.810.810", "start_pos": 810, "end_pos": 810, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "SVIKDIKSTPSKILENSPIL", "down_seq": "RRRSQSISDEKEKAKDNENQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Tyr810" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P25302-1.798.798", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P25302-1.806.806", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P25302-1.814.814", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P25302-1.816.816", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.814.814", "start_pos": 814, "end_pos": 814, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DIKSTPSKILENSPILYRRR", "down_seq": "QSISDEKEKAKDNENQVEKK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser814" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P25302-1.798.798", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P25302-1.806.806", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P25302-1.810.810", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P25302-1.816.816", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.816.816", "start_pos": 816, "end_pos": 816, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast.", "journal": "Science signaling", "date": "2010-12-21", "authors": "Bodenmiller Bernd, Wanka Stefanie, Kraft Claudine, Urban J\u00f6rg, Campbell David, Pedrioli Patrick G, Gerrits Bertran, Picotti Paola, Lam Henry, Vitek Olga, Brusniak Mi-Youn, Roschitzki Bernd, Zhang Chao, Shokat Kevan M, Schlapbach Ralph, Colman-Lerner Alejandro, Nolan Garry P, Nesvizhskii Alexey I, Peter Matthias, Loewith Robbie, von Mering Christian, Aebersold Ruedi", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KSTPSKILENSPILYRRRSQ", "down_seq": "ISDEKEKAKDNENQVEKKKD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser816" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P25302-1.798.798", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P25302-1.806.806", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P25302-1.810.810", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P25302-1.814.814", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.840.840", "start_pos": 840, "end_pos": 840, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EKEKAKDNENQVEKKKDPLN", "down_seq": "VKTAMPSLESPSSLLPIQMS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser840" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "upstream", "id": "P25302-1.850.850", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P25302-1.853.853", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P25302-1.860.860", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.850.850", "start_pos": 850, "end_pos": 850, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QVEKKKDPLNSVKTAMPSLE", "down_seq": "PSSLLPIQMSPLGKYSKPLS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser850" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "P25302-1.840.840", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P25302-1.853.853", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P25302-1.860.860", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P25302-1.870.870", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.853.853", "start_pos": 853, "end_pos": 853, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KKKDPLNSVKTAMPSLESPS", "down_seq": "LLPIQMSPLGKYSKPLSQQI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser853" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P25302-1.840.840", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P25302-1.850.850", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P25302-1.860.860", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P25302-1.870.870", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.860.860", "start_pos": 860, "end_pos": 860, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SVKTAMPSLESPSSLLPIQM", "down_seq": "PLGKYSKPLSQQINKLNTKV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser860" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P25302-1.840.840", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P25302-1.850.850", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P25302-1.853.853", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P25302-1.870.870", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.870.870", "start_pos": 870, "end_pos": 870, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "crossref": [ { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SPSSLLPIQMSPLGKYSKPL", "down_seq": "QQINKLNTKVSSLQRIMGEE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Ser870" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P25302-1.850.850", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P25302-1.853.853", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P25302-1.860.860", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.8.8", "start_pos": 8, "end_pos": 8, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MPFDVLI", "down_seq": "NQKDNTNHQNITPISKSVLL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser8" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "P25302-1.0.0", "categories": [ "glycosylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P25302-1.20.20", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P25302-1.23.23", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.930.930", "start_pos": 930, "end_pos": 930, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "KRLITIAHQIEDAFDSVSNK", "down_seq": "PINSISDLQSRIKETSSKLN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr930" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "upstream", "id": "P25302-1.936.936", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.936.936", "start_pos": 936, "end_pos": 936, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AHQIEDAFDSVSNKTPINSI", "down_seq": "DLQSRIKETSSKLNSEKQNF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser936" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "P25302-1.930.930", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P25302-1.951.951", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25302-1.951.951", "start_pos": 951, "end_pos": 951, "uniprot_canonical_ac": "P25302-1", "length": 1093, "uniprot_id": "SWI4_YEAST", "protein_name": "Regulatory protein SWI4", "refseq_ac": "NP_011036", "refseq_name": "SBF complex DNA-binding subunit SWI4", "gene_name": "SWI4", "gene_names_uniprotkb": "SWI4; ART1", "gene_names_refseq": "ART1; SWI4", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25302", "url": "https://www.uniprot.org/uniprotkb/P25302" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "crossref": [ { "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PINSISDLQSRIKETSSKLN", "down_seq": "EKQNFIQSLEKSQALKLATI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000913", "url": "https://www.yeastgenome.org/locus/S000000913" }, { "database": "iPTMnet", "id": "P25302", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25302" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Ser951" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "23", "end_pos": "23" }, { "start_pos": "456", "end_pos": "456" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "461", "end_pos": "461" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "467", "end_pos": "467" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1003", "end_pos": "1003" }, { "start_pos": "1005", "end_pos": "1005" }, { "start_pos": "1006", "end_pos": "1006" }, { "start_pos": "1007", "end_pos": "1007" }, { "start_pos": "1011", "end_pos": "1011" }, { "start_pos": "1060", "end_pos": "1060" }, { "start_pos": "1061", "end_pos": "1061" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "159", "end_pos": "159" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "180", "end_pos": "180" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "206", "end_pos": "206" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "23", "end_pos": "23" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "687", "end_pos": "687" }, { "start_pos": "692", "end_pos": "692" }, { "start_pos": "694", "end_pos": "694" }, { "start_pos": "744", "end_pos": "744" }, { "start_pos": "798", "end_pos": "798" }, { "start_pos": "806", "end_pos": "806" }, { "start_pos": "810", "end_pos": "810" }, { "start_pos": "814", "end_pos": "814" }, { "start_pos": "816", "end_pos": "816" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "850", "end_pos": "850" }, { "start_pos": "853", "end_pos": "853" }, { "start_pos": "860", "end_pos": "860" }, { "start_pos": "870", "end_pos": "870" }, { "start_pos": "8", "end_pos": "8" }, { "start_pos": "930", "end_pos": "930" }, { "start_pos": "936", "end_pos": "936" }, { "start_pos": "951", "end_pos": "951" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P25302-1.936.936", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25454-1.188.188", "start_pos": 188, "end_pos": 188, "uniprot_canonical_ac": "P25454-1", "length": 400, "uniprot_id": "RAD51_YEAST", "protein_name": "DNA repair protein RAD51", "refseq_ac": "NP_011021", "refseq_name": "recombinase RAD51", "gene_name": "RAD51", "gene_names_uniprotkb": "RAD51", "gene_names_refseq": "MUT5; RAD51", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25454", "url": "https://www.uniprot.org/uniprotkb/P25454" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Rad51 is an accessory factor for Dmc1-mediated joint molecule formation during meiosis.", "journal": "Science (New York, N.Y.)", "date": "2012-09-07", "authors": "Cloud Veronica, Chan Yuen-Ling, Grubb Jennifer, Budke Brian, Bishop Douglas K", "evidence": [ { "database": "UniProtKB", "id": "P25454", "url": "https://www.uniprot.org/uniprotkb/P25454" } ], "reference": [ { "type": "PubMed", "id": "22955832", "url": "https://glygen.org/publication/PubMed/22955832" } ] } ], "crossref": [ { "id": "P25454", "url": "https://www.uniprot.org/uniprotkb/P25454", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "22955832", "url": "https://glygen.org/publication/PubMed/22955832", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "DTLLGGGVETGSITELFGEF", "down_seq": "TGKSQLCHTLAVTCQIPLDI", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "In Rad51-IIA mutant; abolished DNA strand exchange activity without affecting ability to form filaments; when associated with A-361 and A-371.", "evidence": [ { "database": "UniProtKB", "id": "P25454", "url": "https://www.uniprot.org/uniprotkb/P25454" }, { "database": "PubMed", "id": "22955832", "url": "https://glygen.org/publication/PubMed/22955832" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "188", "end_pos": "188" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "371", "end_pos": "371" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "79", "end_pos": "79" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25454-1.352.352", "start_pos": 352, "end_pos": 352, "uniprot_canonical_ac": "P25454-1", "length": 400, "uniprot_id": "RAD51_YEAST", "protein_name": "DNA repair protein RAD51", "refseq_ac": "NP_011021", "refseq_name": "recombinase RAD51", "gene_name": "RAD51", "gene_names_uniprotkb": "RAD51", "gene_names_refseq": "MUT5; RAD51", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25454", "url": "https://www.uniprot.org/uniprotkb/P25454" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Insights into the mechanism of Rad51 recombinase from the structure and properties of a filament interface mutant.", "journal": "Nucleic acids research", "date": "2010-08", "authors": "Chen Jianhong, Villanueva Nicolas, Rould Mark A, Morrical Scott W", "evidence": [ { "database": "UniProtKB", "id": "P25454", "url": "https://www.uniprot.org/uniprotkb/P25454" } ], "reference": [ { "type": "PubMed", "id": "20371520", "url": "https://glygen.org/publication/PubMed/20371520" } ] } ], "crossref": [ { "id": "P25454", "url": "https://www.uniprot.org/uniprotkb/P25454", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "20371520", "url": "https://glygen.org/publication/PubMed/20371520", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "H", "start_aa": "H", "up_seq": "DGGMAFNPDPKKPIGGNIMA", "down_seq": "SSTTRLGFKKGKGCQRLCKV", "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Does not affect the DNA strand exchange activity but forms salt-labile oligomers.", "evidence": [ { "database": "UniProtKB", "id": "P25454", "url": "https://www.uniprot.org/uniprotkb/P25454" }, { "database": "PubMed", "id": "20371520", "url": "https://glygen.org/publication/PubMed/20371520" } ] }, { "sequence_org": "H", "sequence_mut": "Y", "comment": "Impaired DNA strand exchange activity.", "evidence": [ { "database": "UniProtKB", "id": "P25454", "url": "https://www.uniprot.org/uniprotkb/P25454" }, { "database": "PubMed", "id": "20371520", "url": "https://glygen.org/publication/PubMed/20371520" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "188", "end_pos": "188" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "371", "end_pos": "371" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "79", "end_pos": "79" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "P25454-1.353.353", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P25454-1.356.356", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P25454-1.361.361", "categories": [ "mutagenesis_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P25454-1.371.371", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25454-1.361.361", "start_pos": 361, "end_pos": 361, "uniprot_canonical_ac": "P25454-1", "length": 400, "uniprot_id": "RAD51_YEAST", "protein_name": "DNA repair protein RAD51", "refseq_ac": "NP_011021", "refseq_name": "recombinase RAD51", "gene_name": "RAD51", "gene_names_uniprotkb": "RAD51", "gene_names_refseq": "MUT5; RAD51", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25454", "url": "https://www.uniprot.org/uniprotkb/P25454" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Rad51 is an accessory factor for Dmc1-mediated joint molecule formation during meiosis.", "journal": "Science (New York, N.Y.)", "date": "2012-09-07", "authors": "Cloud Veronica, Chan Yuen-Ling, Grubb Jennifer, Budke Brian, Bishop Douglas K", "evidence": [ { "database": "UniProtKB", "id": "P25454", "url": "https://www.uniprot.org/uniprotkb/P25454" } ], "reference": [ { "type": "PubMed", "id": "22955832", "url": "https://glygen.org/publication/PubMed/22955832" } ] } ], "crossref": [ { "id": "P25454", "url": "https://www.uniprot.org/uniprotkb/P25454", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "22955832", "url": "https://glygen.org/publication/PubMed/22955832", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "PKKPIGGNIMAHSSTTRLGF", "down_seq": "KGKGCQRLCKVVDSPCLPEA", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "In Rad51-IIA mutant; abolished DNA strand exchange activity without affecting ability to form filaments; when associated with A-188 and A-371.", "evidence": [ { "database": "UniProtKB", "id": "P25454", "url": "https://www.uniprot.org/uniprotkb/P25454" }, { "database": "PubMed", "id": "22955832", "url": "https://glygen.org/publication/PubMed/22955832" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "188", "end_pos": "188" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "371", "end_pos": "371" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "79", "end_pos": "79" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "P25454-1.352.352", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P25454-1.353.353", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P25454-1.356.356", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P25454-1.371.371", "categories": [ "mutagenesis_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P25454-1.375.375", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25454-1.371.371", "start_pos": 371, "end_pos": 371, "uniprot_canonical_ac": "P25454-1", "length": 400, "uniprot_id": "RAD51_YEAST", "protein_name": "DNA repair protein RAD51", "refseq_ac": "NP_011021", "refseq_name": "recombinase RAD51", "gene_name": "RAD51", "gene_names_uniprotkb": "RAD51", "gene_names_refseq": "MUT5; RAD51", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25454", "url": "https://www.uniprot.org/uniprotkb/P25454" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Rad51 is an accessory factor for Dmc1-mediated joint molecule formation during meiosis.", "journal": "Science (New York, N.Y.)", "date": "2012-09-07", "authors": "Cloud Veronica, Chan Yuen-Ling, Grubb Jennifer, Budke Brian, Bishop Douglas K", "evidence": [ { "database": "UniProtKB", "id": "P25454", "url": "https://www.uniprot.org/uniprotkb/P25454" } ], "reference": [ { "type": "PubMed", "id": "22955832", "url": "https://glygen.org/publication/PubMed/22955832" } ] } ], "crossref": [ { "id": "P25454", "url": "https://www.uniprot.org/uniprotkb/P25454", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "22955832", "url": "https://glygen.org/publication/PubMed/22955832", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "AHSSTTRLGFKKGKGCQRLC", "down_seq": "VVDSPCLPEAECVFAIYEDG", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "In Rad51-IIA mutant; abolished DNA strand exchange activity without affecting ability to form filaments; when associated with A-188 and A-361.", "evidence": [ { "database": "UniProtKB", "id": "P25454", "url": "https://www.uniprot.org/uniprotkb/P25454" }, { "database": "PubMed", "id": "22955832", "url": "https://glygen.org/publication/PubMed/22955832" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "188", "end_pos": "188" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "371", "end_pos": "371" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "79", "end_pos": "79" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P25454-1.352.352", "categories": [ "mutagenesis_flag" ] }, { "distance": 18, "direction": "downstream", "id": "P25454-1.353.353", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P25454-1.356.356", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P25454-1.361.361", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P25454-1.375.375", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25454-1.10.10", "start_pos": 10, "end_pos": 10, "uniprot_canonical_ac": "P25454-1", "length": 400, "uniprot_id": "RAD51_YEAST", "protein_name": "DNA repair protein RAD51", "refseq_ac": "NP_011021", "refseq_name": "recombinase RAD51", "gene_name": "RAD51", "gene_names_uniprotkb": "RAD51", "gene_names_refseq": "MUT5; RAD51", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25454", "url": "https://www.uniprot.org/uniprotkb/P25454" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25454" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000897", "url": "https://www.yeastgenome.org/locus/S000000897", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25454", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MSQVQEQHI", "down_seq": "ESQLQYGNGSLMSTVPADLS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000897", "url": "https://www.yeastgenome.org/locus/S000000897" }, { "database": "iPTMnet", "id": "P25454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25454" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser10" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "188", "end_pos": "188" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "371", "end_pos": "371" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "79", "end_pos": "79" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "P25454-1.2.2", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P25454-1.12.12", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P25454-1.30.30", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25454-1.125.125", "start_pos": 125, "end_pos": 125, "uniprot_canonical_ac": "P25454-1", "length": 400, "uniprot_id": "RAD51_YEAST", "protein_name": "DNA repair protein RAD51", "refseq_ac": "NP_011021", "refseq_name": "recombinase RAD51", "gene_name": "RAD51", "gene_names_uniprotkb": "RAD51", "gene_names_refseq": "MUT5; RAD51", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25454", "url": "https://www.uniprot.org/uniprotkb/P25454" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphoregulation of Rad51/Rad52 by CDK1 functions as a molecular switch for cell cycle-specific activation of homologous recombination.", "journal": "Science advances", "date": "2020-02", "authors": "Lim Gyubum, Chang Yeonji, Huh Won-Ki", "evidence": [ { "database": "iPTMnet", "id": "P25454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25454" } ], "reference": [ { "type": "PubMed", "id": "32083180", "url": "https://glygen.org/publication/PubMed/32083180" } ] } ], "crossref": [ { "id": "P25454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25454", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32083180", "url": "https://glygen.org/publication/PubMed/32083180", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000897", "url": "https://www.yeastgenome.org/locus/S000000897", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "HTAEAVAYAPRKDLLEIKGI", "down_seq": "EAKADKLLNEAARLVPMGFV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25454" }, { "database": "PubMed", "id": "32083180", "url": "https://glygen.org/publication/PubMed/32083180" }, { "database": "SGD", "id": "S000000897", "url": "https://www.yeastgenome.org/locus/S000000897" } ], "site_lbl": "Ser125" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "188", "end_pos": "188" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "371", "end_pos": "371" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "79", "end_pos": "79" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25454-1.12.12", "start_pos": 12, "end_pos": 12, "uniprot_canonical_ac": "P25454-1", "length": 400, "uniprot_id": "RAD51_YEAST", "protein_name": "DNA repair protein RAD51", "refseq_ac": "NP_011021", "refseq_name": "recombinase RAD51", "gene_name": "RAD51", "gene_names_uniprotkb": "RAD51", "gene_names_refseq": "MUT5; RAD51", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25454", "url": "https://www.uniprot.org/uniprotkb/P25454" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Dual roles of yeast Rad51 N-terminal domain in repairing DNA double-strand breaks.", "journal": "Nucleic acids research", "date": "2020-09-04", "authors": "Woo Tai-Ting, Chuang Chi-Ning, Higashide Mika, Shinohara Akira, Wang Ting-Fang", "evidence": [ { "database": "iPTMnet", "id": "P25454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25454" } ], "reference": [ { "type": "PubMed", "id": "32652040", "url": "https://glygen.org/publication/PubMed/32652040" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25454" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P25454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25454", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32652040", "url": "https://glygen.org/publication/PubMed/32652040", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000897", "url": "https://www.yeastgenome.org/locus/S000000897", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MSQVQEQHISE", "down_seq": "QLQYGNGSLMSTVPADLSQS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25454" }, { "database": "PubMed", "id": "32652040", "url": "https://glygen.org/publication/PubMed/32652040" }, { "database": "SGD", "id": "S000000897", "url": "https://www.yeastgenome.org/locus/S000000897" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser12" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "188", "end_pos": "188" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "371", "end_pos": "371" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "79", "end_pos": "79" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "P25454-1.2.2", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P25454-1.10.10", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P25454-1.30.30", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25454-1.2.2", "start_pos": 2, "end_pos": 2, "uniprot_canonical_ac": "P25454-1", "length": 400, "uniprot_id": "RAD51_YEAST", "protein_name": "DNA repair protein RAD51", "refseq_ac": "NP_011021", "refseq_name": "recombinase RAD51", "gene_name": "RAD51", "gene_names_uniprotkb": "RAD51", "gene_names_refseq": "MUT5; RAD51", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25454", "url": "https://www.uniprot.org/uniprotkb/P25454" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Dual roles of yeast Rad51 N-terminal domain in repairing DNA double-strand breaks.", "journal": "Nucleic acids research", "date": "2020-09-04", "authors": "Woo Tai-Ting, Chuang Chi-Ning, Higashide Mika, Shinohara Akira, Wang Ting-Fang", "evidence": [ { "database": "iPTMnet", "id": "P25454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25454" } ], "reference": [ { "type": "PubMed", "id": "32652040", "url": "https://glygen.org/publication/PubMed/32652040" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25454" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000897", "url": "https://www.yeastgenome.org/locus/S000000897", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25454", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32652040", "url": "https://glygen.org/publication/PubMed/32652040", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "M", "down_seq": "QVQEQHISESQLQYGNGSLM", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000897", "url": "https://www.yeastgenome.org/locus/S000000897" }, { "database": "iPTMnet", "id": "P25454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25454" }, { "database": "PubMed", "id": "32652040", "url": "https://glygen.org/publication/PubMed/32652040" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser2" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "188", "end_pos": "188" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "371", "end_pos": "371" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "79", "end_pos": "79" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "upstream", "id": "P25454-1.10.10", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P25454-1.12.12", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25454-1.30.30", "start_pos": 30, "end_pos": 30, "uniprot_canonical_ac": "P25454-1", "length": 400, "uniprot_id": "RAD51_YEAST", "protein_name": "DNA repair protein RAD51", "refseq_ac": "NP_011021", "refseq_name": "recombinase RAD51", "gene_name": "RAD51", "gene_names_uniprotkb": "RAD51", "gene_names_refseq": "MUT5; RAD51", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25454", "url": "https://www.uniprot.org/uniprotkb/P25454" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Dual roles of yeast Rad51 N-terminal domain in repairing DNA double-strand breaks.", "journal": "Nucleic acids research", "date": "2020-09-04", "authors": "Woo Tai-Ting, Chuang Chi-Ning, Higashide Mika, Shinohara Akira, Wang Ting-Fang", "evidence": [ { "database": "iPTMnet", "id": "P25454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25454" } ], "reference": [ { "type": "PubMed", "id": "32652040", "url": "https://glygen.org/publication/PubMed/32652040" } ] } ], "crossref": [ { "id": "P25454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25454", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32652040", "url": "https://glygen.org/publication/PubMed/32652040", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000897", "url": "https://www.yeastgenome.org/locus/S000000897", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SESQLQYGNGSLMSTVPADL", "down_seq": "QSVVDGNGNGSSEDIEATNG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25454" }, { "database": "PubMed", "id": "32652040", "url": "https://glygen.org/publication/PubMed/32652040" }, { "database": "SGD", "id": "S000000897", "url": "https://www.yeastgenome.org/locus/S000000897" } ], "site_lbl": "Ser30" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "188", "end_pos": "188" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "371", "end_pos": "371" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "79", "end_pos": "79" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P25454-1.10.10", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "downstream", "id": "P25454-1.12.12", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25454-1.353.353", "start_pos": 353, "end_pos": 353, "uniprot_canonical_ac": "P25454-1", "length": 400, "uniprot_id": "RAD51_YEAST", "protein_name": "DNA repair protein RAD51", "refseq_ac": "NP_011021", "refseq_name": "recombinase RAD51", "gene_name": "RAD51", "gene_names_uniprotkb": "RAD51", "gene_names_refseq": "MUT5; RAD51", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25454", "url": "https://www.uniprot.org/uniprotkb/P25454" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cell cycle phosphorylation of mitotic exit network (MEN) proteins.", "journal": "Cell cycle (Georgetown, Tex.)", "date": "2011-10-15", "authors": "Jones Michele H, Keck Jamie M, Wong Catherine C L, Xu Tao, Yates John R, Winey Mark", "evidence": [ { "database": "iPTMnet", "id": "P25454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25454" } ], "reference": [ { "type": "PubMed", "id": "22031224", "url": "https://glygen.org/publication/PubMed/22031224" } ] } ], "crossref": [ { "id": "S000000897", "url": "https://www.yeastgenome.org/locus/S000000897", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25454", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "22031224", "url": "https://glygen.org/publication/PubMed/22031224", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GGMAFNPDPKKPIGGNIMAH", "down_seq": "STTRLGFKKGKGCQRLCKVV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000897", "url": "https://www.yeastgenome.org/locus/S000000897" }, { "database": "iPTMnet", "id": "P25454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25454" }, { "database": "PubMed", "id": "22031224", "url": "https://glygen.org/publication/PubMed/22031224" } ], "site_lbl": "Ser353" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "188", "end_pos": "188" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "371", "end_pos": "371" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "79", "end_pos": "79" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "P25454-1.352.352", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P25454-1.356.356", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P25454-1.361.361", "categories": [ "mutagenesis_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P25454-1.371.371", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25454-1.356.356", "start_pos": 356, "end_pos": 356, "uniprot_canonical_ac": "P25454-1", "length": 400, "uniprot_id": "RAD51_YEAST", "protein_name": "DNA repair protein RAD51", "refseq_ac": "NP_011021", "refseq_name": "recombinase RAD51", "gene_name": "RAD51", "gene_names_uniprotkb": "RAD51", "gene_names_refseq": "MUT5; RAD51", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25454", "url": "https://www.uniprot.org/uniprotkb/P25454" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cell cycle phosphorylation of mitotic exit network (MEN) proteins.", "journal": "Cell cycle (Georgetown, Tex.)", "date": "2011-10-15", "authors": "Jones Michele H, Keck Jamie M, Wong Catherine C L, Xu Tao, Yates John R, Winey Mark", "evidence": [ { "database": "iPTMnet", "id": "P25454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25454" } ], "reference": [ { "type": "PubMed", "id": "22031224", "url": "https://glygen.org/publication/PubMed/22031224" } ] } ], "crossref": [ { "id": "S000000897", "url": "https://www.yeastgenome.org/locus/S000000897", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25454", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "22031224", "url": "https://glygen.org/publication/PubMed/22031224", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "AFNPDPKKPIGGNIMAHSST", "down_seq": "RLGFKKGKGCQRLCKVVDSP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000897", "url": "https://www.yeastgenome.org/locus/S000000897" }, { "database": "iPTMnet", "id": "P25454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25454" }, { "database": "PubMed", "id": "22031224", "url": "https://glygen.org/publication/PubMed/22031224" } ], "site_lbl": "Thr356" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "188", "end_pos": "188" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "371", "end_pos": "371" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "79", "end_pos": "79" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P25454-1.352.352", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P25454-1.353.353", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P25454-1.361.361", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P25454-1.371.371", "categories": [ "mutagenesis_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P25454-1.375.375", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25454-1.375.375", "start_pos": 375, "end_pos": 375, "uniprot_canonical_ac": "P25454-1", "length": 400, "uniprot_id": "RAD51_YEAST", "protein_name": "DNA repair protein RAD51", "refseq_ac": "NP_011021", "refseq_name": "recombinase RAD51", "gene_name": "RAD51", "gene_names_uniprotkb": "RAD51", "gene_names_refseq": "MUT5; RAD51", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25454", "url": "https://www.uniprot.org/uniprotkb/P25454" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphoregulation of Rad51/Rad52 by CDK1 functions as a molecular switch for cell cycle-specific activation of homologous recombination.", "journal": "Science advances", "date": "2020-02", "authors": "Lim Gyubum, Chang Yeonji, Huh Won-Ki", "evidence": [ { "database": "iPTMnet", "id": "P25454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25454" } ], "reference": [ { "type": "PubMed", "id": "32083180", "url": "https://glygen.org/publication/PubMed/32083180" } ] } ], "crossref": [ { "id": "P25454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25454", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32083180", "url": "https://glygen.org/publication/PubMed/32083180", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000897", "url": "https://www.yeastgenome.org/locus/S000000897", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TTRLGFKKGKGCQRLCKVVD", "down_seq": "PCLPEAECVFAIYEDGVGDP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25454" }, { "database": "PubMed", "id": "32083180", "url": "https://glygen.org/publication/PubMed/32083180" }, { "database": "SGD", "id": "S000000897", "url": "https://www.yeastgenome.org/locus/S000000897" } ], "site_lbl": "Ser375" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "188", "end_pos": "188" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "371", "end_pos": "371" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "79", "end_pos": "79" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P25454-1.356.356", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P25454-1.361.361", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P25454-1.371.371", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25454-1.79.79", "start_pos": 79, "end_pos": 79, "uniprot_canonical_ac": "P25454-1", "length": 400, "uniprot_id": "RAD51_YEAST", "protein_name": "DNA repair protein RAD51", "refseq_ac": "NP_011021", "refseq_name": "recombinase RAD51", "gene_name": "RAD51", "gene_names_uniprotkb": "RAD51", "gene_names_refseq": "MUT5; RAD51", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25454", "url": "https://www.uniprot.org/uniprotkb/P25454" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25454" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000897", "url": "https://www.yeastgenome.org/locus/S000000897", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25454", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EQAEAQGEMEDEAYDEAALG", "down_seq": "FVPIEKLQVNGITMADVKKL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000897", "url": "https://www.yeastgenome.org/locus/S000000897" }, { "database": "iPTMnet", "id": "P25454", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25454" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser79" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "188", "end_pos": "188" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "371", "end_pos": "371" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "375", "end_pos": "375" }, { "start_pos": "79", "end_pos": "79" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25638-1.70.70", "start_pos": 70, "end_pos": 70, "uniprot_canonical_ac": "P25638-1", "length": 111, "uniprot_id": "TAH1_YEAST", "protein_name": "TPR repeat-containing protein associated with Hsp90", "refseq_ac": "NP_009986", "refseq_name": "Tah1p", "gene_name": "TAH1", "gene_names_uniprotkb": "TAH1; YCR60W", "gene_names_refseq": "TAH1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25638", "url": "https://www.uniprot.org/uniprotkb/P25638" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25638", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25638" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000656", "url": "https://www.yeastgenome.org/locus/S000000656", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25638", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25638", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "KLGEYTQAIQMCQQGLRYTS", "down_seq": "AEHVAIRSKLQYRLELAQGA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000656", "url": "https://www.yeastgenome.org/locus/S000000656" }, { "database": "iPTMnet", "id": "P25638", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25638" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr70" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "70", "end_pos": "70" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25655-1.1257.1257", "start_pos": 1257, "end_pos": 1257, "uniprot_canonical_ac": "P25655-1", "length": 2108, "uniprot_id": "NOT1_YEAST", "protein_name": "General negative regulator of transcription subunit 1", "refseq_ac": "NP_010017", "refseq_name": "CCR4-NOT core subunit CDC39", "gene_name": "CDC39", "gene_names_uniprotkb": "CDC39; NOT1; ROS1; YCR1151; YCR93W", "gene_names_refseq": "CDC39; NOT1; ROS1; SMD6", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25655", "url": "https://www.uniprot.org/uniprotkb/P25655" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P25655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25655" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ], "crossref": [ { "id": "S000000689", "url": "https://www.yeastgenome.org/locus/S000000689", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25655", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "ITQNTNPYSLSLPEPLGLKN", "down_seq": "GVTPQQFRVYEEFGKNIPNL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000689", "url": "https://www.yeastgenome.org/locus/S000000689" }, { "database": "iPTMnet", "id": "P25655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25655" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ], "site_lbl": "Thr1257" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1257", "end_pos": "1257" }, { "start_pos": "1260", "end_pos": "1260" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "2094", "end_pos": "2094" }, { "start_pos": "2102", "end_pos": "2102" }, { "start_pos": "2106", "end_pos": "2106" }, { "start_pos": "755", "end_pos": "755" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "P25655-1.1260.1260", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25655-1.1260.1260", "start_pos": 1260, "end_pos": 1260, "uniprot_canonical_ac": "P25655-1", "length": 2108, "uniprot_id": "NOT1_YEAST", "protein_name": "General negative regulator of transcription subunit 1", "refseq_ac": "NP_010017", "refseq_name": "CCR4-NOT core subunit CDC39", "gene_name": "CDC39", "gene_names_uniprotkb": "CDC39; NOT1; ROS1; YCR1151; YCR93W", "gene_names_refseq": "CDC39; NOT1; ROS1; SMD6", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25655", "url": "https://www.uniprot.org/uniprotkb/P25655" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P25655", "url": "https://www.uniprot.org/uniprotkb/P25655" }, { "database": "iPTMnet", "id": "P25655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25655" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P25655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25655" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25655" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25655" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P25655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25655", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000689", "url": "https://www.yeastgenome.org/locus/S000000689", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "NTNPYSLSLPEPLGLKNTGV", "down_seq": "PQQFRVYEEFGKNIPNLDVI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25655" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000689", "url": "https://www.yeastgenome.org/locus/S000000689" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr1260" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1257", "end_pos": "1257" }, { "start_pos": "1260", "end_pos": "1260" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "2094", "end_pos": "2094" }, { "start_pos": "2102", "end_pos": "2102" }, { "start_pos": "2106", "end_pos": "2106" }, { "start_pos": "755", "end_pos": "755" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P25655-1.1257.1257", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25655-1.140.140", "start_pos": 140, "end_pos": 140, "uniprot_canonical_ac": "P25655-1", "length": 2108, "uniprot_id": "NOT1_YEAST", "protein_name": "General negative regulator of transcription subunit 1", "refseq_ac": "NP_010017", "refseq_name": "CCR4-NOT core subunit CDC39", "gene_name": "CDC39", "gene_names_uniprotkb": "CDC39; NOT1; ROS1; YCR1151; YCR93W", "gene_names_refseq": "CDC39; NOT1; ROS1; SMD6", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25655", "url": "https://www.uniprot.org/uniprotkb/P25655" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25655" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000689", "url": "https://www.yeastgenome.org/locus/S000000689", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25655", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QEFQKQTGITLSLFIDLFDK", "down_seq": "ANKDIIESLDRSSQINDFKT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000689", "url": "https://www.yeastgenome.org/locus/S000000689" }, { "database": "iPTMnet", "id": "P25655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25655" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser140" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1257", "end_pos": "1257" }, { "start_pos": "1260", "end_pos": "1260" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "2094", "end_pos": "2094" }, { "start_pos": "2102", "end_pos": "2102" }, { "start_pos": "2106", "end_pos": "2106" }, { "start_pos": "755", "end_pos": "755" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25655-1.2094.2094", "start_pos": 2094, "end_pos": 2094, "uniprot_canonical_ac": "P25655-1", "length": 2108, "uniprot_id": "NOT1_YEAST", "protein_name": "General negative regulator of transcription subunit 1", "refseq_ac": "NP_010017", "refseq_name": "CCR4-NOT core subunit CDC39", "gene_name": "CDC39", "gene_names_uniprotkb": "CDC39; NOT1; ROS1; YCR1151; YCR93W", "gene_names_refseq": "CDC39; NOT1; ROS1; SMD6", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25655", "url": "https://www.uniprot.org/uniprotkb/P25655" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25655" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000689", "url": "https://www.yeastgenome.org/locus/S000000689", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25655", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ILQQLVKYSKKYTTSEQDDQ", "down_seq": "ATINRRQTPLQSNA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000689", "url": "https://www.yeastgenome.org/locus/S000000689" }, { "database": "iPTMnet", "id": "P25655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25655" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser2094" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1257", "end_pos": "1257" }, { "start_pos": "1260", "end_pos": "1260" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "2094", "end_pos": "2094" }, { "start_pos": "2102", "end_pos": "2102" }, { "start_pos": "2106", "end_pos": "2106" }, { "start_pos": "755", "end_pos": "755" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "upstream", "id": "P25655-1.2102.2102", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P25655-1.2106.2106", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25655-1.2102.2102", "start_pos": 2102, "end_pos": 2102, "uniprot_canonical_ac": "P25655-1", "length": 2108, "uniprot_id": "NOT1_YEAST", "protein_name": "General negative regulator of transcription subunit 1", "refseq_ac": "NP_010017", "refseq_name": "CCR4-NOT core subunit CDC39", "gene_name": "CDC39", "gene_names_uniprotkb": "CDC39; NOT1; ROS1; YCR1151; YCR93W", "gene_names_refseq": "CDC39; NOT1; ROS1; SMD6", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25655", "url": "https://www.uniprot.org/uniprotkb/P25655" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P25655", "url": "https://www.uniprot.org/uniprotkb/P25655" }, { "database": "iPTMnet", "id": "P25655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25655" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.", "journal": "Molecular & cellular proteomics : MCP", "date": "2005-03", "authors": "Gruhler Albrecht, Olsen Jesper V, Mohammed Shabaz, Mortensen Peter, Faergeman Nils J, Mann Matthias, Jensen Ole N", "evidence": [ { "database": "UniProtKB", "id": "P25655", "url": "https://www.uniprot.org/uniprotkb/P25655" }, { "database": "iPTMnet", "id": "P25655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25655" } ], "reference": [ { "type": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" } ] }, { "title": "Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae.", "journal": "Nature biotechnology", "date": "2002-03", "authors": "Ficarro Scott B, McCleland Mark L, Stukenberg P Todd, Burke Daniel J, Ross Mark M, Shabanowitz Jeffrey, Hunt Donald F, White Forest M", "evidence": [ { "database": "iPTMnet", "id": "P25655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25655" } ], "reference": [ { "type": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "iPTMnet", "id": "P25655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25655" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast.", "journal": "Proteomics", "date": "2009-10", "authors": "Gnad Florian, de Godoy Lyris M F, Cox J\u00fcrgen, Neuhauser Nadin, Ren Shubin, Olsen Jesper V, Mann Matthias", "evidence": [ { "database": "iPTMnet", "id": "P25655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25655" } ], "reference": [ { "type": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" } ] }, { "title": "Global analysis of the yeast osmotic stress response by quantitative proteomics.", "journal": "Molecular bioSystems", "date": "2009-11", "authors": "Soufi Boumediene, Kelstrup Christian D, Stoehr Gabriele, Fr\u00f6hlich Florian, Walther Tobias C, Olsen Jesper V", "evidence": [ { "database": "iPTMnet", "id": "P25655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25655" } ], "reference": [ { "type": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] }, { "title": "Phosphorylation of Not4p functions parallel to BUR2 to regulate resistance to cellular stresses in Saccharomyces cerevisiae.", "journal": "PloS one", "date": "2010-04-08", "authors": "Lau Nga-Chi, Mulder Klaas W, Brenkman Arjan B, Mohammed Shabaz, van den Broek Niels J F, Heck Albert J R, Timmers H Th Marc", "evidence": [ { "database": "iPTMnet", "id": "P25655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25655" } ], "reference": [ { "type": "PubMed", "id": "20386698", "url": "https://glygen.org/publication/PubMed/20386698" } ] }, { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P25655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25655" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "Global mapping of protein phosphorylation events identifies Ste20, Sch9 and the cell-cycle regulatory kinases Cdc28/Pho85 as mediators of fatty acid starvation responses in Saccharomyces cerevisiae.", "journal": "Molecular bioSystems", "date": "2012-03", "authors": "Pultz Dennis, Bennetzen Martin V, R\u00f8dk\u00e6r Steven Vestergaard, Zimmermann Christine, Enserink Jorrit M, Andersen Jens S, F\u00e6rgeman Nils J", "evidence": [ { "database": "iPTMnet", "id": "P25655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25655" } ], "reference": [ { "type": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P25655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25655" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P25655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25655" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25655" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25655" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P25655", "url": "https://www.uniprot.org/uniprotkb/P25655", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P25655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25655", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20386698", "url": "https://glygen.org/publication/PubMed/20386698", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000689", "url": "https://www.yeastgenome.org/locus/S000000689", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SKKYTTSEQDDQSATINRRQ", "down_seq": "PLQSNA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P25655", "url": "https://www.uniprot.org/uniprotkb/P25655" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "iPTMnet", "id": "P25655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25655" }, { "database": "PubMed", "id": "11875433", "url": "https://glygen.org/publication/PubMed/11875433" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20386698", "url": "https://glygen.org/publication/PubMed/20386698" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000000689", "url": "https://www.yeastgenome.org/locus/S000000689" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr2102" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1257", "end_pos": "1257" }, { "start_pos": "1260", "end_pos": "1260" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "2094", "end_pos": "2094" }, { "start_pos": "2102", "end_pos": "2102" }, { "start_pos": "2106", "end_pos": "2106" }, { "start_pos": "755", "end_pos": "755" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "P25655-1.2094.2094", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P25655-1.2106.2106", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 13 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25655-1.2106.2106", "start_pos": 2106, "end_pos": 2106, "uniprot_canonical_ac": "P25655-1", "length": 2108, "uniprot_id": "NOT1_YEAST", "protein_name": "General negative regulator of transcription subunit 1", "refseq_ac": "NP_010017", "refseq_name": "CCR4-NOT core subunit CDC39", "gene_name": "CDC39", "gene_names_uniprotkb": "CDC39; NOT1; ROS1; YCR1151; YCR93W", "gene_names_refseq": "CDC39; NOT1; ROS1; SMD6", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25655", "url": "https://www.uniprot.org/uniprotkb/P25655" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P25655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25655" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ], "crossref": [ { "id": "S000000689", "url": "https://www.yeastgenome.org/locus/S000000689", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25655", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TTSEQDDQSATINRRQTPLQ", "down_seq": "NA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000689", "url": "https://www.yeastgenome.org/locus/S000000689" }, { "database": "iPTMnet", "id": "P25655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25655" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ], "site_lbl": "Ser2106" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1257", "end_pos": "1257" }, { "start_pos": "1260", "end_pos": "1260" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "2094", "end_pos": "2094" }, { "start_pos": "2102", "end_pos": "2102" }, { "start_pos": "2106", "end_pos": "2106" }, { "start_pos": "755", "end_pos": "755" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P25655-1.2094.2094", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P25655-1.2102.2102", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25655-1.755.755", "start_pos": 755, "end_pos": 755, "uniprot_canonical_ac": "P25655-1", "length": 2108, "uniprot_id": "NOT1_YEAST", "protein_name": "General negative regulator of transcription subunit 1", "refseq_ac": "NP_010017", "refseq_name": "CCR4-NOT core subunit CDC39", "gene_name": "CDC39", "gene_names_uniprotkb": "CDC39; NOT1; ROS1; YCR1151; YCR93W", "gene_names_refseq": "CDC39; NOT1; ROS1; SMD6", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25655", "url": "https://www.uniprot.org/uniprotkb/P25655" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25655" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000689", "url": "https://www.yeastgenome.org/locus/S000000689", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25655", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AQVYQSIVEAATLANAPKER", "down_seq": "RPVQEMIPLKFFAVDEVSCQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000689", "url": "https://www.yeastgenome.org/locus/S000000689" }, { "database": "iPTMnet", "id": "P25655", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25655" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser755" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1257", "end_pos": "1257" }, { "start_pos": "1260", "end_pos": "1260" }, { "start_pos": "140", "end_pos": "140" }, { "start_pos": "2094", "end_pos": "2094" }, { "start_pos": "2102", "end_pos": "2102" }, { "start_pos": "2106", "end_pos": "2106" }, { "start_pos": "755", "end_pos": "755" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25693-1.201.201", "start_pos": 201, "end_pos": 201, "uniprot_canonical_ac": "P25693-1", "length": 308, "uniprot_id": "PCL2_YEAST", "protein_name": "PHO85 cyclin-2", "refseq_ac": "NP_010156", "refseq_name": "cyclin PCL2", "gene_name": "PCL2", "gene_names_uniprotkb": "PCL2; CLN4; D2223", "gene_names_refseq": "CLN4; PCL2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25693", "url": "https://www.uniprot.org/uniprotkb/P25693" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25693", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25693" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000002285", "url": "https://www.yeastgenome.org/locus/S000002285", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25693", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25693", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FSAQEKDIVNKTSISHSRSS", "down_seq": "NMSIPSLASTSTLSTLESRR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000002285", "url": "https://www.yeastgenome.org/locus/S000002285" }, { "database": "iPTMnet", "id": "P25693", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25693" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser201" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "201", "end_pos": "201" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25693-1.222.222", "start_pos": 222, "end_pos": 222, "uniprot_canonical_ac": "P25693-1", "length": 308, "uniprot_id": "PCL2_YEAST", "protein_name": "PHO85 cyclin-2", "refseq_ac": "NP_010156", "refseq_name": "cyclin PCL2", "gene_name": "PCL2", "gene_names_uniprotkb": "PCL2; CLN4; D2223", "gene_names_refseq": "CLN4; PCL2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25693", "url": "https://www.uniprot.org/uniprotkb/P25693" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25693", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25693" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000002285", "url": "https://www.yeastgenome.org/locus/S000002285", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25693", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25693", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NMSIPSLASTSTLSTLESRR", "down_seq": "NLSNYSNRIRTLPELHESNN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000002285", "url": "https://www.yeastgenome.org/locus/S000002285" }, { "database": "iPTMnet", "id": "P25693", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25693" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser222" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "201", "end_pos": "201" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25693-1.248.248", "start_pos": 248, "end_pos": 248, "uniprot_canonical_ac": "P25693-1", "length": 308, "uniprot_id": "PCL2_YEAST", "protein_name": "PHO85 cyclin-2", "refseq_ac": "NP_010156", "refseq_name": "cyclin PCL2", "gene_name": "PCL2", "gene_names_uniprotkb": "PCL2; CLN4; D2223", "gene_names_refseq": "CLN4; PCL2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25693", "url": "https://www.uniprot.org/uniprotkb/P25693" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25693", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25693" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000002285", "url": "https://www.yeastgenome.org/locus/S000002285", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25693", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25693", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SNRIRTLPELHESNNISDKF", "down_seq": "PRTYNIDSKHDNKENRPIPT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000002285", "url": "https://www.yeastgenome.org/locus/S000002285" }, { "database": "iPTMnet", "id": "P25693", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25693" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser248" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "201", "end_pos": "201" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25693-1.38.38", "start_pos": 38, "end_pos": 38, "uniprot_canonical_ac": "P25693-1", "length": 308, "uniprot_id": "PCL2_YEAST", "protein_name": "PHO85 cyclin-2", "refseq_ac": "NP_010156", "refseq_name": "cyclin PCL2", "gene_name": "PCL2", "gene_names_uniprotkb": "PCL2; CLN4; D2223", "gene_names_refseq": "CLN4; PCL2", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25693", "url": "https://www.uniprot.org/uniprotkb/P25693" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25693", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25693" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000002285", "url": "https://www.yeastgenome.org/locus/S000002285", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25693", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25693", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EMVQYLASTTASIIKIKKTN", "down_seq": "MIDIALPAPPLTKFINRLIK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000002285", "url": "https://www.yeastgenome.org/locus/S000002285" }, { "database": "iPTMnet", "id": "P25693", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25693" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser38" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "201", "end_pos": "201" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.261.261", "start_pos": 261, "end_pos": 261, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Positive cooperativity of the p97 AAA ATPase is critical for essential functions.", "journal": "The Journal of biological chemistry", "date": "2011-05-06", "authors": "Nishikori Shingo, Esaki Masatoshi, Yamanaka Kunitoshi, Sugimoto Shinya, Ogura Teru", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "reference": [ { "type": "PubMed", "id": "21454554", "url": "https://glygen.org/publication/PubMed/21454554" } ] } ], "crossref": [ { "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21454554", "url": "https://glygen.org/publication/PubMed/21454554", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "KAIGIKPPRGVLMYGPPGTG", "down_seq": "TLMARAVANETGAFFFLING", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Moderate reduction in growth rate.", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "PubMed", "id": "21454554", "url": "https://glygen.org/publication/PubMed/21454554" } ] }, { "sequence_org": "K", "sequence_mut": "T", "comment": "Probable loss of ATP binding. Complete loss of catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "PubMed", "id": "21454554", "url": "https://glygen.org/publication/PubMed/21454554" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.315.315", "start_pos": 315, "end_pos": 315, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Positive cooperativity of the p97 AAA ATPase is critical for essential functions.", "journal": "The Journal of biological chemistry", "date": "2011-05-06", "authors": "Nishikori Shingo, Esaki Masatoshi, Yamanaka Kunitoshi, Sugimoto Shinya, Ogura Teru", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "reference": [ { "type": "PubMed", "id": "21454554", "url": "https://glygen.org/publication/PubMed/21454554" } ] } ], "crossref": [ { "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21454554", "url": "https://glygen.org/publication/PubMed/21454554", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "E", "start_aa": "E", "up_seq": "NLRKAFEEAEKNAPAIIFID", "down_seq": "IDSIAPKRDKTNGEVERRVV", "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Moderate reduction in growth rate.", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "PubMed", "id": "21454554", "url": "https://glygen.org/publication/PubMed/21454554" } ] }, { "sequence_org": "E", "sequence_mut": "D", "comment": "Severe loss of catalytic activity without affecting cooperativity between the 2 ATP-binding regions. Slight reduction in growth rate.", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "PubMed", "id": "21454554", "url": "https://glygen.org/publication/PubMed/21454554" } ] }, { "sequence_org": "E", "sequence_mut": "N", "comment": "Severe reduction in growth rate.", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "PubMed", "id": "21454554", "url": "https://glygen.org/publication/PubMed/21454554" } ] }, { "sequence_org": "E", "sequence_mut": "Q", "comment": "Severe loss of catalytic activity and cooperativity between the 2 ATP-binding regions. Lethal. Restores cell growth; when associated with A-358; A-369; S-471; A-471 or H-475.", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "PubMed", "id": "21454554", "url": "https://glygen.org/publication/PubMed/21454554" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "P25694-1.318.318", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.358.358", "start_pos": 358, "end_pos": 358, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Positive cooperativity of the p97 AAA ATPase is critical for essential functions.", "journal": "The Journal of biological chemistry", "date": "2011-05-06", "authors": "Nishikori Shingo, Esaki Masatoshi, Yamanaka Kunitoshi, Sugimoto Shinya, Ogura Teru", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "reference": [ { "type": "PubMed", "id": "21454554", "url": "https://glygen.org/publication/PubMed/21454554" } ] } ], "crossref": [ { "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21454554", "url": "https://glygen.org/publication/PubMed/21454554", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "LLTLMDGMKARSNVVVIAAT", "down_seq": "RPNSIDPALRRFGRFDREVD", "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "A", "comment": "Slight reduction in growth rate. Restores cell growth; when associated with Q-315.", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "PubMed", "id": "21454554", "url": "https://glygen.org/publication/PubMed/21454554" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P25694-1.340.340", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P25694-1.369.369", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.369.369", "start_pos": 369, "end_pos": 369, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Positive cooperativity of the p97 AAA ATPase is critical for essential functions.", "journal": "The Journal of biological chemistry", "date": "2011-05-06", "authors": "Nishikori Shingo, Esaki Masatoshi, Yamanaka Kunitoshi, Sugimoto Shinya, Ogura Teru", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "reference": [ { "type": "PubMed", "id": "21454554", "url": "https://glygen.org/publication/PubMed/21454554" } ] }, { "title": "Physical and genetic associations of the Irc20 ubiquitin ligase with Cdc48 and SUMO.", "journal": "PloS one", "date": "2013", "authors": "Richardson Aaron, Gardner Richard G, Prelich Gregory", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "reference": [ { "type": "PubMed", "id": "24155900", "url": "https://glygen.org/publication/PubMed/24155900" } ] } ], "crossref": [ { "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21454554", "url": "https://glygen.org/publication/PubMed/21454554", "database": "PubMed", "categories": [ "Other" ] }, { "id": "24155900", "url": "https://glygen.org/publication/PubMed/24155900", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "SNVVVIAATNRPNSIDPALR", "down_seq": "FGRFDREVDIGIPDATGRLE", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "No effect on growth rate. Restores cell growth; when associated with Q-315.", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "PubMed", "id": "21454554", "url": "https://glygen.org/publication/PubMed/21454554" } ] }, { "sequence_org": "R", "sequence_mut": "K", "comment": "Cold sensitive.", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "PubMed", "id": "24155900", "url": "https://glygen.org/publication/PubMed/24155900" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P25694-1.358.358", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.471.471", "start_pos": 471, "end_pos": 471, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Positive cooperativity of the p97 AAA ATPase is critical for essential functions.", "journal": "The Journal of biological chemistry", "date": "2011-05-06", "authors": "Nishikori Shingo, Esaki Masatoshi, Yamanaka Kunitoshi, Sugimoto Shinya, Ogura Teru", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "reference": [ { "type": "PubMed", "id": "21454554", "url": "https://glygen.org/publication/PubMed/21454554" } ] } ], "crossref": [ { "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21454554", "url": "https://glygen.org/publication/PubMed/21454554", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "P", "start_aa": "P", "up_seq": "VLDSLGVTMDNFRFALGNSN", "down_seq": "SALRETVVESVNVTWDDVGG", "mutagenesis": [ { "sequence_org": "P", "sequence_mut": "A", "comment": "Restores cell growth; when associated with Q-315.", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "PubMed", "id": "21454554", "url": "https://glygen.org/publication/PubMed/21454554" } ] }, { "sequence_org": "P", "sequence_mut": "S", "comment": "Restores cell growth; when associated with Q-315.", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "PubMed", "id": "21454554", "url": "https://glygen.org/publication/PubMed/21454554" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P25694-1.469.469", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P25694-1.472.472", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P25694-1.475.475", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.475.475", "start_pos": 475, "end_pos": 475, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Positive cooperativity of the p97 AAA ATPase is critical for essential functions.", "journal": "The Journal of biological chemistry", "date": "2011-05-06", "authors": "Nishikori Shingo, Esaki Masatoshi, Yamanaka Kunitoshi, Sugimoto Shinya, Ogura Teru", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "reference": [ { "type": "PubMed", "id": "21454554", "url": "https://glygen.org/publication/PubMed/21454554" } ] } ], "crossref": [ { "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21454554", "url": "https://glygen.org/publication/PubMed/21454554", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "LGVTMDNFRFALGNSNPSAL", "down_seq": "ETVVESVNVTWDDVGGLDEI", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "H", "comment": "Restores cell growth; when associated with Q-315.", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "PubMed", "id": "21454554", "url": "https://glygen.org/publication/PubMed/21454554" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "P25694-1.469.469", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P25694-1.471.471", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P25694-1.472.472", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.534.534", "start_pos": 534, "end_pos": 534, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Positive cooperativity of the p97 AAA ATPase is critical for essential functions.", "journal": "The Journal of biological chemistry", "date": "2011-05-06", "authors": "Nishikori Shingo, Esaki Masatoshi, Yamanaka Kunitoshi, Sugimoto Shinya, Ogura Teru", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "reference": [ { "type": "PubMed", "id": "21454554", "url": "https://glygen.org/publication/PubMed/21454554" } ] } ], "crossref": [ { "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21454554", "url": "https://glygen.org/publication/PubMed/21454554", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "TKFGLSPSKGVLFYGPPGTG", "down_seq": "TLLAKAVATEVSANFISVKG", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Severe loss of catalytic activity. Lethal.", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "PubMed", "id": "21454554", "url": "https://glygen.org/publication/PubMed/21454554" } ] }, { "sequence_org": "K", "sequence_mut": "T", "comment": "Severe loss of catalytic activity. Lethal.", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "PubMed", "id": "21454554", "url": "https://glygen.org/publication/PubMed/21454554" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P25694-1.519.519", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P25694-1.521.521", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P25694-1.532.532", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P25694-1.535.535", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.588.588", "start_pos": 588, "end_pos": 588, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Positive cooperativity of the p97 AAA ATPase is critical for essential functions.", "journal": "The Journal of biological chemistry", "date": "2011-05-06", "authors": "Nishikori Shingo, Esaki Masatoshi, Yamanaka Kunitoshi, Sugimoto Shinya, Ogura Teru", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "reference": [ { "type": "PubMed", "id": "21454554", "url": "https://glygen.org/publication/PubMed/21454554" } ] } ], "crossref": [ { "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21454554", "url": "https://glygen.org/publication/PubMed/21454554", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "E", "start_aa": "E", "up_seq": "NIRDIFDKARAAAPTVVFLD", "down_seq": "LDSIAKARGGSLGDAGGASD", "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "D", "comment": "Moderate reduction in growth rate.", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "PubMed", "id": "21454554", "url": "https://glygen.org/publication/PubMed/21454554" } ] }, { "sequence_org": "E", "sequence_mut": "Q", "comment": "Lethal.", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "PubMed", "id": "21454554", "url": "https://glygen.org/publication/PubMed/21454554" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "P25694-1.591.591", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P25694-1.599.599", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P25694-1.607.607", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.645.645", "start_pos": 645, "end_pos": 645, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Positive cooperativity of the p97 AAA ATPase is critical for essential functions.", "journal": "The Journal of biological chemistry", "date": "2011-05-06", "authors": "Nishikori Shingo, Esaki Masatoshi, Yamanaka Kunitoshi, Sugimoto Shinya, Ogura Teru", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "reference": [ { "type": "PubMed", "id": "21454554", "url": "https://glygen.org/publication/PubMed/21454554" } ] } ], "crossref": [ { "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21454554", "url": "https://glygen.org/publication/PubMed/21454554", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "KNVFVIGATNRPDQIDPAIL", "down_seq": "PGRLDQLIYVPLPDENARLS", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Lethal.", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "PubMed", "id": "21454554", "url": "https://glygen.org/publication/PubMed/21454554" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "upstream", "id": "P25694-1.665.665", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.12.12", "start_pos": 12, "end_pos": 12, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] }, { "title": "Phosphoproteomic responses of TORC1 target kinases reveal discrete and convergent mechanisms that orchestrate the quiescence program in yeast.", "journal": "Cell reports", "date": "2021-12-28", "authors": "Dokl\u00e1dal Ladislav, Stumpe Michael, Hu Zehan, Jaquenoud Malika, Dengjel J\u00f6rn, De Virgilio Claudio", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ] } ], "crossref": [ { "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MGEEHKPLLDA", "down_seq": "GVDPREEDKTATAILRRKKK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ], "site_lbl": "Ser12" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "upstream", "id": "P25694-1.22.22", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P25694-1.24.24", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.22.22", "start_pos": 22, "end_pos": 22, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "GEEHKPLLDASGVDPREEDK", "down_seq": "ATAILRRKKKDNMLLVDDAI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr22" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "P25694-1.12.12", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P25694-1.24.24", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.24.24", "start_pos": 24, "end_pos": 24, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "EHKPLLDASGVDPREEDKTA", "down_seq": "AILRRKKKDNMLLVDDAIND", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr24" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P25694-1.12.12", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P25694-1.22.22", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.292.292", "start_pos": 292, "end_pos": 292, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TGAFFFLINGPEVMSKMAGE", "down_seq": "ESNLRKAFEEAEKNAPAIIF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser292" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P25694-1.294.294", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.294.294", "start_pos": 294, "end_pos": 294, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AFFFLINGPEVMSKMAGESE", "down_seq": "NLRKAFEEAEKNAPAIIFID", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser294" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P25694-1.292.292", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.318.318", "start_pos": 318, "end_pos": 318, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ], "crossref": [ { "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KAFEEAEKNAPAIIFIDEID", "down_seq": "IAPKRDKTNGEVERRVVSQL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284" } ], "site_lbl": "Ser318" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P25694-1.315.315", "categories": [ "mutagenesis_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P25694-1.336.336", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.336.336", "start_pos": 336, "end_pos": 336, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IDSIAPKRDKTNGEVERRVV", "down_seq": "QLLTLMDGMKARSNVVVIAA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser336" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P25694-1.318.318", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P25694-1.340.340", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.340.340", "start_pos": 340, "end_pos": 340, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] } ], "crossref": [ { "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "APKRDKTNGEVERRVVSQLL", "down_seq": "LMDGMKARSNVVVIAATNRP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Thr340" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P25694-1.336.336", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P25694-1.358.358", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.423.423", "start_pos": 423, "end_pos": 423, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ], "crossref": [ { "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DVDLEALAAETHGYVGADIA", "down_seq": "LCSEAAMQQIREKMDLIDLD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284" } ], "site_lbl": "Ser423" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.469.469", "start_pos": 469, "end_pos": 469, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AEVLDSLGVTMDNFRFALGN", "down_seq": "NPSALRETVVESVNVTWDDV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser469" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P25694-1.471.471", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P25694-1.472.472", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P25694-1.475.475", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.472.472", "start_pos": 472, "end_pos": 472, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LDSLGVTMDNFRFALGNSNP", "down_seq": "ALRETVVESVNVTWDDVGGL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" }, { "database": "SGD", "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser472" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P25694-1.469.469", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P25694-1.471.471", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P25694-1.475.475", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.519.519", "start_pos": 519, "end_pos": 519, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "Journal of proteome research", "date": "2007-03", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.", "journal": "Molecular & cellular proteomics : MCP", "date": "2005-03", "authors": "Gruhler Albrecht, Olsen Jesper V, Mohammed Shabaz, Mortensen Peter, Faergeman Nils J, Mann Matthias, Jensen Ole N", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" } ] }, { "title": "Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-06-19", "authors": "Smolka Marcus B, Albuquerque Claudio P, Chen Sheng-hong, Zhou Huilin", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.", "journal": "Genes & development", "date": "2009-08-15", "authors": "Huber Alexandre, Bodenmiller Bernd, Uotila Aino, Stahl Michael, Wanka Stefanie, Gerrits Bertran, Aebersold Ruedi, Loewith Robbie", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] }, { "title": "High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast.", "journal": "Proteomics", "date": "2009-10", "authors": "Gnad Florian, de Godoy Lyris M F, Cox J\u00fcrgen, Neuhauser Nadin, Ren Shubin, Olsen Jesper V, Mann Matthias", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" } ] }, { "title": "Global analysis of the yeast osmotic stress response by quantitative proteomics.", "journal": "Molecular bioSystems", "date": "2009-11", "authors": "Soufi Boumediene, Kelstrup Christian D, Stoehr Gabriele, Fr\u00f6hlich Florian, Walther Tobias C, Olsen Jesper V", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] }, { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] }, { "title": "Global mapping of protein phosphorylation events identifies Ste20, Sch9 and the cell-cycle regulatory kinases Cdc28/Pho85 as mediators of fatty acid starvation responses in Saccharomyces cerevisiae.", "journal": "Molecular bioSystems", "date": "2012-03", "authors": "Pultz Dennis, Bennetzen Martin V, R\u00f8dk\u00e6r Steven Vestergaard, Zimmermann Christine, Enserink Jorrit M, Andersen Jens S, F\u00e6rgeman Nils J", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Quantitative proteomics identifies unanticipated regulators of nitrogen- and glucose starvation.", "journal": "Molecular bioSystems", "date": "2014-08", "authors": "R\u00f8dk\u00e6r Steven V, Pultz Dennis, Brusch Michelle, Bennetzen Martin V, Falkenby Lasse G, Andersen Jens S, F\u00e6rgeman Nils J", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LKETVEYPVLHPDQYTKFGL", "down_seq": "PSKGVLFYGPPGTGKTLLAK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser519" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P25694-1.521.521", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P25694-1.532.532", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P25694-1.534.534", "categories": [ "mutagenesis_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P25694-1.535.535", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 16 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.521.521", "start_pos": 521, "end_pos": 521, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast.", "journal": "Proteomics", "date": "2009-10", "authors": "Gnad Florian, de Godoy Lyris M F, Cox J\u00fcrgen, Neuhauser Nadin, Ren Shubin, Olsen Jesper V, Mann Matthias", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" } ] }, { "title": "Global analysis of the yeast osmotic stress response by quantitative proteomics.", "journal": "Molecular bioSystems", "date": "2009-11", "authors": "Soufi Boumediene, Kelstrup Christian D, Stoehr Gabriele, Fr\u00f6hlich Florian, Walther Tobias C, Olsen Jesper V", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ETVEYPVLHPDQYTKFGLSP", "down_seq": "KGVLFYGPPGTGKTLLAKAV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" }, { "database": "SGD", "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser521" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P25694-1.519.519", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P25694-1.532.532", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P25694-1.534.534", "categories": [ "mutagenesis_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P25694-1.535.535", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.532.532", "start_pos": 532, "end_pos": 532, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "QYTKFGLSPSKGVLFYGPPG", "down_seq": "GKTLLAKAVATEVSANFISV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr532" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P25694-1.519.519", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P25694-1.521.521", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P25694-1.534.534", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P25694-1.535.535", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.535.535", "start_pos": 535, "end_pos": 535, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "KFGLSPSKGVLFYGPPGTGK", "down_seq": "LLAKAVATEVSANFISVKGP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr535" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P25694-1.519.519", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P25694-1.521.521", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P25694-1.532.532", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P25694-1.534.534", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.565.565", "start_pos": 565, "end_pos": 565, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VSANFISVKGPELLSMWYGE", "down_seq": "ESNIRDIFDKARAAAPTVVF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser565" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P25694-1.567.567", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.567.567", "start_pos": 567, "end_pos": 567, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ANFISVKGPELLSMWYGESE", "down_seq": "NIRDIFDKARAAAPTVVFLD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser567" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P25694-1.565.565", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.591.591", "start_pos": 591, "end_pos": 591, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DIFDKARAAAPTVVFLDELD", "down_seq": "IAKARGGSLGDAGGASDRVV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser591" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P25694-1.588.588", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P25694-1.599.599", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P25694-1.607.607", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.599.599", "start_pos": 599, "end_pos": 599, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Glucose intake hampers PKA-regulated HSP90 chaperone activity.", "journal": "eLife", "date": "2018-12-05", "authors": "Chen Yu-Chen, Jiang Pei-Heng, Chen Hsuan-Ming, Chen Chang-Han, Wang Yi-Ting, Chen Yu-Ju, Yu Chia-Jung, Teng Shu-Chun", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AAPTVVFLDELDSIAKARGG", "down_seq": "LGDAGGASDRVVNQLLTEMD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser599" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P25694-1.588.588", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P25694-1.591.591", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P25694-1.607.607", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.607.607", "start_pos": 607, "end_pos": 607, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DELDSIAKARGGSLGDAGGA", "down_seq": "DRVVNQLLTEMDGMNAKKNV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser607" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P25694-1.588.588", "categories": [ "mutagenesis_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P25694-1.591.591", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P25694-1.599.599", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.665.665", "start_pos": 665, "end_pos": 665, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RPGRLDQLIYVPLPDENARL", "down_seq": "ILNAQLRKTPLEPGLELTAI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser665" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P25694-1.645.645", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P25694-1.674.674", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P25694-1.683.683", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.66.66", "start_pos": 66, "end_pos": 66, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "NSVIAINSNTMDKLELFRGD", "down_seq": "VLVKGKKRKDTVLIVLIDDE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr66" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.674.674", "start_pos": 674, "end_pos": 674, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "YVPLPDENARLSILNAQLRK", "down_seq": "PLEPGLELTAIAKATQGFSG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr674" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "P25694-1.665.665", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P25694-1.683.683", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.683.683", "start_pos": 683, "end_pos": 683, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A proteomics approach to understanding protein ubiquitination.", "journal": "Nat. Biotechnol.", "date": "2003", "authors": "Peng Junmin, Schwartz Daniel, Elias Joshua E, Thoreen Carson C, Cheng Dongmei, Marsischky Gerald, Roelofs Jeroen, Finley Daniel, Gygi Steven P", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "12872131", "url": "https://glygen.org/publication/PubMed/12872131" } ] } ], "crossref": [ { "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "12872131", "url": "https://glygen.org/publication/PubMed/12872131", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "RLSILNAQLRKTPLEPGLEL", "down_seq": "AIAKATQGFSGADLLYIVQR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" }, { "database": "PubMed", "id": "12872131", "url": "https://glygen.org/publication/PubMed/12872131" } ], "site_lbl": "Thr683" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P25694-1.665.665", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P25694-1.674.674", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.735.735", "start_pos": 735, "end_pos": 735, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-06-19", "authors": "Smolka Marcus B, Albuquerque Claudio P, Chen Sheng-hong, Zhou Huilin", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] }, { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] }, { "title": "Global mapping of protein phosphorylation events identifies Ste20, Sch9 and the cell-cycle regulatory kinases Cdc28/Pho85 as mediators of fatty acid starvation responses in Saccharomyces cerevisiae.", "journal": "Molecular bioSystems", "date": "2012-03", "authors": "Pultz Dennis, Bennetzen Martin V, R\u00f8dk\u00e6r Steven Vestergaard, Zimmermann Christine, Enserink Jorrit M, Andersen Jens S, F\u00e6rgeman Nils J", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Quantitative proteomics identifies unanticipated regulators of nitrogen- and glucose starvation.", "journal": "Molecular bioSystems", "date": "2014-08", "authors": "R\u00f8dk\u00e6r Steven V, Pultz Dennis, Brusch Michelle, Bennetzen Martin V, Falkenby Lasse G, Andersen Jens S, F\u00e6rgeman Nils J", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "AHRQHEAEKEVKVEGEDVEM", "down_seq": "DEGAKAEQEPEVDPVPYITK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284" }, { "database": "PubMed", "id": "22218487", "url": "https://glygen.org/publication/PubMed/22218487" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr735" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 10 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.768.768", "start_pos": 768, "end_pos": 768, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DPVPYITKEHFAEAMKTAKR", "down_seq": "VSDAELRRYEAYSQQMKASR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser768" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P25694-1.770.770", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P25694-1.781.781", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P25694-1.787.787", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.770.770", "start_pos": 770, "end_pos": 770, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-02-13", "authors": "Chi An, Huttenhower Curtis, Geer Lewis Y, Coon Joshua J, Syka John E P, Bai Dina L, Shabanowitz Jeffrey, Burke Daniel J, Troyanskaya Olga G, Hunt Donald F", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] }, { "title": "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.", "journal": "Journal of proteome research", "date": "2007-03", "authors": "Li Xue, Gerber Scott A, Rudner Adam D, Beausoleil Sean A, Haas Wilhelm, Vill\u00e9n Judit, Elias Joshua E, Gygi Steve P", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" } ] }, { "title": "Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-06-19", "authors": "Smolka Marcus B, Albuquerque Claudio P, Chen Sheng-hong, Zhou Huilin", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast.", "journal": "Science signaling", "date": "2010-12-21", "authors": "Bodenmiller Bernd, Wanka Stefanie, Kraft Claudine, Urban J\u00f6rg, Campbell David, Pedrioli Patrick G, Gerrits Bertran, Picotti Paola, Lam Henry, Vitek Olga, Brusniak Mi-Youn, Roschitzki Bernd, Zhang Chao, Shokat Kevan M, Schlapbach Ralph, Colman-Lerner Alejandro, Nolan Garry P, Nesvizhskii Alexey I, Peter Matthias, Loewith Robbie, von Mering Christian, Aebersold Ruedi", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Quantitative proteomics identifies unanticipated regulators of nitrogen- and glucose starvation.", "journal": "Molecular bioSystems", "date": "2014-08", "authors": "R\u00f8dk\u00e6r Steven V, Pultz Dennis, Brusch Michelle, Bennetzen Martin V, Falkenby Lasse G, Andersen Jens S, F\u00e6rgeman Nils J", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VPYITKEHFAEAMKTAKRSV", "down_seq": "DAELRRYEAYSQQMKASRGQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "PubMed", "id": "17330950", "url": "https://glygen.org/publication/PubMed/17330950" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser770" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P25694-1.768.768", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P25694-1.781.781", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P25694-1.787.787", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 13 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.781.781", "start_pos": 781, "end_pos": 781, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AMKTAKRSVSDAELRRYEAY", "down_seq": "QQMKASRGQFSNFNFNDAPL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser781" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P25694-1.768.768", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P25694-1.770.770", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P25694-1.787.787", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.787.787", "start_pos": 787, "end_pos": 787, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast.", "journal": "Proteomics", "date": "2009-10", "authors": "Gnad Florian, de Godoy Lyris M F, Cox J\u00fcrgen, Neuhauser Nadin, Ren Shubin, Olsen Jesper V, Mann Matthias", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" } ] }, { "title": "Global analysis of the yeast osmotic stress response by quantitative proteomics.", "journal": "Molecular bioSystems", "date": "2009-11", "authors": "Soufi Boumediene, Kelstrup Christian D, Stoehr Gabriele, Fr\u00f6hlich Florian, Walther Tobias C, Olsen Jesper V", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ] } ], "crossref": [ { "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RSVSDAELRRYEAYSQQMKA", "down_seq": "RGQFSNFNFNDAPLGTTATD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" }, { "database": "PubMed", "id": "19795423", "url": "https://glygen.org/publication/PubMed/19795423" }, { "database": "PubMed", "id": "19823750", "url": "https://glygen.org/publication/PubMed/19823750" } ], "site_lbl": "Ser787" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P25694-1.768.768", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P25694-1.770.770", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P25694-1.781.781", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P25694-1.825.825", "start_pos": 825, "end_pos": 825, "uniprot_canonical_ac": "P25694-1", "length": 835, "uniprot_id": "CDC48_YEAST", "protein_name": "AAA family ATPase involved in ubiquitin-mediated protein degradation CDC48", "refseq_ac": "NP_010157", "refseq_name": "AAA family ATPase CDC48", "gene_name": "CDC48", "gene_names_uniprotkb": "CDC48", "gene_names_refseq": "CDC48", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P25694", "url": "https://www.uniprot.org/uniprotkb/P25694" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ATDNANSNNSAPSGAGAAFG", "down_seq": "NAEEDDDLYS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000002284", "url": "https://www.yeastgenome.org/locus/S000002284" }, { "database": "iPTMnet", "id": "P25694", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P25694" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser825" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "471", "end_pos": "471" }, { "start_pos": "475", "end_pos": "475" }, { "start_pos": "534", "end_pos": "534" }, { "start_pos": "588", "end_pos": "588" }, { "start_pos": "645", "end_pos": "645" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "12", "end_pos": "12" }, { "start_pos": "22", "end_pos": "22" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "336", "end_pos": "336" }, { "start_pos": "340", "end_pos": "340" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "469", "end_pos": "469" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "532", "end_pos": "532" }, { "start_pos": "535", "end_pos": "535" }, { "start_pos": "565", "end_pos": "565" }, { "start_pos": "567", "end_pos": "567" }, { "start_pos": "591", "end_pos": "591" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "607", "end_pos": "607" }, { "start_pos": "665", "end_pos": "665" }, { "start_pos": "66", "end_pos": "66" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "683", "end_pos": "683" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "768", "end_pos": "768" }, { "start_pos": "770", "end_pos": "770" }, { "start_pos": "781", "end_pos": "781" }, { "start_pos": "787", "end_pos": "787" }, { "start_pos": "825", "end_pos": "825" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27616-1.126.126", "start_pos": 126, "end_pos": 126, "uniprot_canonical_ac": "P27616-1", "length": 306, "uniprot_id": "PUR7_YEAST", "protein_name": "Phosphoribosylaminoimidazole-succinocarboxamide synthase", "refseq_ac": "NP_009409", "refseq_name": "phosphoribosylaminoimidazolesuccinocarboxamide synthase", "gene_name": "ADE1", "gene_names_uniprotkb": "ADE1", "gene_names_refseq": "ADE1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27616", "url": "https://www.uniprot.org/uniprotkb/P27616" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P27616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27616" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000070", "url": "https://www.yeastgenome.org/locus/S000000070", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P27616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27616", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SLLVHKHKLIPLEVIVRGYI", "down_seq": "GSAWKEYVKTGTVHGLKQPQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000070", "url": "https://www.yeastgenome.org/locus/S000000070" }, { "database": "iPTMnet", "id": "P27616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27616" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr126" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "126", "end_pos": "126" }, { "start_pos": "128", "end_pos": "128" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "175", "end_pos": "175" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "2", "end_pos": "2" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P27616-1.128.128", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27616-1.128.128", "start_pos": 128, "end_pos": 128, "uniprot_canonical_ac": "P27616-1", "length": 306, "uniprot_id": "PUR7_YEAST", "protein_name": "Phosphoribosylaminoimidazole-succinocarboxamide synthase", "refseq_ac": "NP_009409", "refseq_name": "phosphoribosylaminoimidazolesuccinocarboxamide synthase", "gene_name": "ADE1", "gene_names_uniprotkb": "ADE1", "gene_names_refseq": "ADE1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27616", "url": "https://www.uniprot.org/uniprotkb/P27616" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P27616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27616" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000070", "url": "https://www.yeastgenome.org/locus/S000000070", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P27616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27616", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LVHKHKLIPLEVIVRGYITG", "down_seq": "AWKEYVKTGTVHGLKQPQGL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000070", "url": "https://www.yeastgenome.org/locus/S000000070" }, { "database": "iPTMnet", "id": "P27616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27616" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser128" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "126", "end_pos": "126" }, { "start_pos": "128", "end_pos": "128" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "175", "end_pos": "175" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "2", "end_pos": "2" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P27616-1.126.126", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27616-1.160.160", "start_pos": 160, "end_pos": 160, "uniprot_canonical_ac": "P27616-1", "length": 306, "uniprot_id": "PUR7_YEAST", "protein_name": "Phosphoribosylaminoimidazole-succinocarboxamide synthase", "refseq_ac": "NP_009409", "refseq_name": "phosphoribosylaminoimidazolesuccinocarboxamide synthase", "gene_name": "ADE1", "gene_names_uniprotkb": "ADE1", "gene_names_refseq": "ADE1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27616", "url": "https://www.uniprot.org/uniprotkb/P27616" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Molecular & cellular proteomics : MCP", "date": "2008-07", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "iPTMnet", "id": "P27616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27616" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P27616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27616" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P27616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27616", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000000070", "url": "https://www.yeastgenome.org/locus/S000000070", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "HGLKQPQGLKESQEFPEPIF", "down_seq": "PSTKAEQGEHDENISPAQAA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P27616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27616" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000000070", "url": "https://www.yeastgenome.org/locus/S000000070" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr160" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "126", "end_pos": "126" }, { "start_pos": "128", "end_pos": "128" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "175", "end_pos": "175" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "2", "end_pos": "2" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "upstream", "id": "P27616-1.175.175", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27616-1.175.175", "start_pos": 175, "end_pos": 175, "uniprot_canonical_ac": "P27616-1", "length": 306, "uniprot_id": "PUR7_YEAST", "protein_name": "Phosphoribosylaminoimidazole-succinocarboxamide synthase", "refseq_ac": "NP_009409", "refseq_name": "phosphoribosylaminoimidazolesuccinocarboxamide synthase", "gene_name": "ADE1", "gene_names_uniprotkb": "ADE1", "gene_names_refseq": "ADE1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27616", "url": "https://www.uniprot.org/uniprotkb/P27616" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P27616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27616" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000070", "url": "https://www.yeastgenome.org/locus/S000000070", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P27616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27616", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PEPIFTPSTKAEQGEHDENI", "down_seq": "PAQAAELVGEDLSRRVAELA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000070", "url": "https://www.yeastgenome.org/locus/S000000070" }, { "database": "iPTMnet", "id": "P27616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27616" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser175" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "126", "end_pos": "126" }, { "start_pos": "128", "end_pos": "128" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "175", "end_pos": "175" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "2", "end_pos": "2" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P27616-1.160.160", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27616-1.254.254", "start_pos": 254, "end_pos": 254, "uniprot_canonical_ac": "P27616-1", "length": 306, "uniprot_id": "PUR7_YEAST", "protein_name": "Phosphoribosylaminoimidazole-succinocarboxamide synthase", "refseq_ac": "NP_009409", "refseq_name": "phosphoribosylaminoimidazolesuccinocarboxamide synthase", "gene_name": "ADE1", "gene_names_uniprotkb": "ADE1", "gene_names_refseq": "ADE1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27616", "url": "https://www.uniprot.org/uniprotkb/P27616" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P27616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27616" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000070", "url": "https://www.yeastgenome.org/locus/S000000070", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P27616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27616", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EVLTPDSSRFWNGASYKVGE", "down_seq": "QDSYDKQFLRDWLTANKLNG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000070", "url": "https://www.yeastgenome.org/locus/S000000070" }, { "database": "iPTMnet", "id": "P27616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27616" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser254" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "126", "end_pos": "126" }, { "start_pos": "128", "end_pos": "128" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "175", "end_pos": "175" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "2", "end_pos": "2" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "P27616-1.257.257", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27616-1.257.257", "start_pos": 257, "end_pos": 257, "uniprot_canonical_ac": "P27616-1", "length": 306, "uniprot_id": "PUR7_YEAST", "protein_name": "Phosphoribosylaminoimidazole-succinocarboxamide synthase", "refseq_ac": "NP_009409", "refseq_name": "phosphoribosylaminoimidazolesuccinocarboxamide synthase", "gene_name": "ADE1", "gene_names_uniprotkb": "ADE1", "gene_names_refseq": "ADE1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27616", "url": "https://www.uniprot.org/uniprotkb/P27616" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P27616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27616" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000070", "url": "https://www.yeastgenome.org/locus/S000000070", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P27616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27616", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TPDSSRFWNGASYKVGESQD", "down_seq": "YDKQFLRDWLTANKLNGVNG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000070", "url": "https://www.yeastgenome.org/locus/S000000070" }, { "database": "iPTMnet", "id": "P27616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27616" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser257" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "126", "end_pos": "126" }, { "start_pos": "128", "end_pos": "128" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "175", "end_pos": "175" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "2", "end_pos": "2" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P27616-1.254.254", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27616-1.2.2", "start_pos": 2, "end_pos": 2, "uniprot_canonical_ac": "P27616-1", "length": 306, "uniprot_id": "PUR7_YEAST", "protein_name": "Phosphoribosylaminoimidazole-succinocarboxamide synthase", "refseq_ac": "NP_009409", "refseq_name": "phosphoribosylaminoimidazolesuccinocarboxamide synthase", "gene_name": "ADE1", "gene_names_uniprotkb": "ADE1", "gene_names_refseq": "ADE1", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27616", "url": "https://www.uniprot.org/uniprotkb/P27616" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P27616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27616" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000000070", "url": "https://www.yeastgenome.org/locus/S000000070", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P27616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27616", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "M", "down_seq": "ITKTELDGILPLVARGKVRD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000000070", "url": "https://www.yeastgenome.org/locus/S000000070" }, { "database": "iPTMnet", "id": "P27616", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27616" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser2" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "126", "end_pos": "126" }, { "start_pos": "128", "end_pos": "128" }, { "start_pos": "160", "end_pos": "160" }, { "start_pos": "175", "end_pos": "175" }, { "start_pos": "254", "end_pos": "254" }, { "start_pos": "257", "end_pos": "257" }, { "start_pos": "2", "end_pos": "2" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.1009.1009", "start_pos": 1009, "end_pos": 1009, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P27692", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P27692" }, { "database": "O-GlcNAc Atlas", "id": "P27692", "url": "https://oglcnac.org/atlas/detail/P27692" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] }, { "title": "The transcription factor Spt4-Spt5 complex regulates the expression of ATG8 and ATG41.", "journal": "Autophagy", "date": "2020-07", "authors": "Wen Xin, Gatica Dami\u00e1n, Yin Zhangyuan, Hu Zehan, Dengjel J\u00f6rn, Klionsky Daniel J", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "reference": [ { "type": "PubMed", "id": "31462158", "url": "https://glygen.org/publication/PubMed/31462158" } ] }, { "title": "Phosphorylation of the transcription elongation factor Spt5 by yeast Bur1 kinase stimulates recruitment of the PAF complex.", "journal": "Molecular and cellular biology", "date": "2009-09", "authors": "Liu Ying, Warfield Linda, Zhang Chao, Luo Jie, Allen Jasmina, Lang Walter H, Ranish Jeffrey, Shokat Kevan M, Hahn Steven", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P27692", "url": "https://oglcnac.org/atlas/detail/P27692", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "31462158", "url": "https://glygen.org/publication/PubMed/31462158", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "WASGGESNGAMSTWGGTGDR", "down_seq": "AYGGASTWGGNNNNKSTRDG", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1009", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P27692", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P27692" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Reduces autophagic activity; when associated with A-1015; A-1025; A-1032; A-1043; A-1052 and A-1058.", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "PubMed", "id": "31462158", "url": "https://glygen.org/publication/PubMed/31462158" } ] }, { "sequence_org": "S", "sequence_mut": "E", "comment": "Phosphomimetic mutation that exhibits up-regulated autophagy activity; when associated with E-1015; E-1025; E-1032; E-1043; E-1052 and E-1058.", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "PubMed", "id": "31462158", "url": "https://glygen.org/publication/PubMed/31462158" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P23293-1", "kinase_gene_name": "SGV1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" } ], "site_lbl": "Ser1009" }, { "kinase_uniprot_canonical_ac": "Q05949-1", "kinase_gene_name": "BUR2", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" } ], "site_lbl": "Ser1009" }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "PubMed", "id": "31462158", "url": "https://glygen.org/publication/PubMed/31462158" }, { "database": "SGD", "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser1009" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "glycosylation_flag", "mutagenesis_flag", "phosphorylation_flag" ], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "P27692-1.1000.1000", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P27692-1.1015.1015", "categories": [ "glycosylation_flag", "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P27692-1.1025.1025", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.1015.1015", "start_pos": 1015, "end_pos": 1015, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P27692", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P27692" }, { "database": "O-GlcNAc Atlas", "id": "P27692", "url": "https://oglcnac.org/atlas/detail/P27692" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] }, { "title": "The transcription factor Spt4-Spt5 complex regulates the expression of ATG8 and ATG41.", "journal": "Autophagy", "date": "2020-07", "authors": "Wen Xin, Gatica Dami\u00e1n, Yin Zhangyuan, Hu Zehan, Dengjel J\u00f6rn, Klionsky Daniel J", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "reference": [ { "type": "PubMed", "id": "31462158", "url": "https://glygen.org/publication/PubMed/31462158" } ] }, { "title": "Phosphorylation of the transcription elongation factor Spt5 by yeast Bur1 kinase stimulates recruitment of the PAF complex.", "journal": "Molecular and cellular biology", "date": "2009-09", "authors": "Liu Ying, Warfield Linda, Zhang Chao, Luo Jie, Allen Jasmina, Lang Walter H, Ranish Jeffrey, Shokat Kevan M, Hahn Steven", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P27692", "url": "https://oglcnac.org/atlas/detail/P27692", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "31462158", "url": "https://glygen.org/publication/PubMed/31462158", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SNGAMSTWGGTGDRSAYGGA", "down_seq": "TWGGNNNNKSTRDGGASAWG", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1015", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P27692", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P27692" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Reduces autophagic activity; when associated with A-1009; A-1025; A-1032; A-1043; A-1052 and A-1058.", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "PubMed", "id": "31462158", "url": "https://glygen.org/publication/PubMed/31462158" } ] }, { "sequence_org": "S", "sequence_mut": "E", "comment": "Phosphomimetic mutation that exhibits up-regulated autophagy activity; when associated with E-1009; E-1025; E-1032; E-1043; E-1052 and E-1058.", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "PubMed", "id": "31462158", "url": "https://glygen.org/publication/PubMed/31462158" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P23293-1", "kinase_gene_name": "SGV1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ], "site_lbl": "Ser1015" }, { "kinase_uniprot_canonical_ac": "Q05949-1", "kinase_gene_name": "BUR2", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ], "site_lbl": "Ser1015" }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "PubMed", "id": "31462158", "url": "https://glygen.org/publication/PubMed/31462158" }, { "database": "SGD", "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser1015" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "glycosylation_flag", "mutagenesis_flag", "phosphorylation_flag" ], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P27692-1.1000.1000", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P27692-1.1009.1009", "categories": [ "glycosylation_flag", "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P27692-1.1025.1025", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P27692-1.1032.1032", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.241.241", "start_pos": 241, "end_pos": 241, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P27692", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P27692" }, { "database": "O-GlcNAc Atlas", "id": "P27692", "url": "https://oglcnac.org/atlas/detail/P27692" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P27692", "url": "https://oglcnac.org/atlas/detail/P27692", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PGARRDDRLHRQLDQDLNKT", "down_seq": "EEDAQRLAKELRERYGRSSS", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser241", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P27692", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P27692" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser241" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "P27692-1.240.240", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.501.501", "start_pos": 501, "end_pos": 501, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [], "crossref": [ { "id": "GLY_001160", "url": "https://data.glygen.org/GLY_001160", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "DGYLYKSFRIQHVETKNIQP", "down_seq": "VEELARFGSKEGAVDLTSVS", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr501", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P27692-1.783.783", "start_pos": 783, "end_pos": 783, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P27692", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P27692" }, { "database": "O-GlcNAc Atlas", "id": "P27692", "url": "https://oglcnac.org/atlas/detail/P27692" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P27692", "url": "https://oglcnac.org/atlas/detail/P27692", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SNKMDLSKMNPEIISKMGPP", "down_seq": "SKTFQQPIQSRGGREVALGK", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser783", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P27692", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P27692" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "P27692-1.784.784", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P27692-1.793.793", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.784.784", "start_pos": 784, "end_pos": 784, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P27692", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P27692" }, { "database": "O-GlcNAc Atlas", "id": "P27692", "url": "https://oglcnac.org/atlas/detail/P27692" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P27692", "url": "https://oglcnac.org/atlas/detail/P27692", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NKMDLSKMNPEIISKMGPPS", "down_seq": "KTFQQPIQSRGGREVALGKT", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser784", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P27692", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P27692" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "P27692-1.783.783", "categories": [ "glycosylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P27692-1.793.793", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "P27692", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P27692" }, { "database": "O-GlcNAc Atlas", "id": "P27692", "url": "https://oglcnac.org/atlas/detail/P27692" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] } ], "crossref": [ { "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P27692", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P27692", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "P27692", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P27692" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P27692-1.2.2", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P27692-1.5.5", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P27692-1.7.7", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.1025.1025", "start_pos": 1025, "end_pos": 1025, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "The transcription factor Spt4-Spt5 complex regulates the expression of ATG8 and ATG41.", "journal": "Autophagy", "date": "2020-07", "authors": "Wen Xin, Gatica Dami\u00e1n, Yin Zhangyuan, Hu Zehan, Dengjel J\u00f6rn, Klionsky Daniel J", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "reference": [ { "type": "PubMed", "id": "31462158", "url": "https://glygen.org/publication/PubMed/31462158" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] } ], "crossref": [ { "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "31462158", "url": "https://glygen.org/publication/PubMed/31462158", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TGDRSAYGGASTWGGNNNNK", "down_seq": "TRDGGASAWGNQDDGNRSAW", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Reduces autophagic activity; when associated with A-1009; A-1015; A-1032; A-1043; A-1052 and A-1058.", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "PubMed", "id": "31462158", "url": "https://glygen.org/publication/PubMed/31462158" } ] }, { "sequence_org": "S", "sequence_mut": "E", "comment": "Phosphomimetic mutation that exhibits up-regulated autophagy activity; when associated with E-1009; E-1015; E-1032; E-1043; E-1052 and E-1058.", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "PubMed", "id": "31462158", "url": "https://glygen.org/publication/PubMed/31462158" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "PubMed", "id": "31462158", "url": "https://glygen.org/publication/PubMed/31462158" }, { "database": "SGD", "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ], "site_lbl": "Ser1025" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "mutagenesis_flag", "phosphorylation_flag" ], "glycosylation": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P27692-1.1009.1009", "categories": [ "glycosylation_flag", "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P27692-1.1015.1015", "categories": [ "glycosylation_flag", "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P27692-1.1032.1032", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P27692-1.1043.1043", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.1032.1032", "start_pos": 1032, "end_pos": 1032, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "The transcription factor Spt4-Spt5 complex regulates the expression of ATG8 and ATG41.", "journal": "Autophagy", "date": "2020-07", "authors": "Wen Xin, Gatica Dami\u00e1n, Yin Zhangyuan, Hu Zehan, Dengjel J\u00f6rn, Klionsky Daniel J", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "reference": [ { "type": "PubMed", "id": "31462158", "url": "https://glygen.org/publication/PubMed/31462158" } ] }, { "title": "Phosphorylation of the transcription elongation factor Spt5 by yeast Bur1 kinase stimulates recruitment of the PAF complex.", "journal": "Molecular and cellular biology", "date": "2009-09", "authors": "Liu Ying, Warfield Linda, Zhang Chao, Luo Jie, Allen Jasmina, Lang Walter H, Ranish Jeffrey, Shokat Kevan M, Hahn Steven", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" } ] }, { "title": "Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.", "journal": "Genes & development", "date": "2009-08-15", "authors": "Huber Alexandre, Bodenmiller Bernd, Uotila Aino, Stahl Michael, Wanka Stefanie, Gerrits Bertran, Aebersold Ruedi, Loewith Robbie", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "31462158", "url": "https://glygen.org/publication/PubMed/31462158", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GGASTWGGNNNNKSTRDGGA", "down_seq": "AWGNQDDGNRSAWNNQGNKS", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Reduces autophagic activity; when associated with A-1009; A-1015; A-1025; A-1043; A-1052 and A-1058.", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "PubMed", "id": "31462158", "url": "https://glygen.org/publication/PubMed/31462158" } ] }, { "sequence_org": "S", "sequence_mut": "E", "comment": "Phosphomimetic mutation that exhibits up-regulated autophagy activity; when associated with E-1009; E-1015; E-1025; E-1043; E-1052 and E-1058.", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "PubMed", "id": "31462158", "url": "https://glygen.org/publication/PubMed/31462158" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P23293-1", "kinase_gene_name": "SGV1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ], "site_lbl": "Ser1032" }, { "kinase_uniprot_canonical_ac": "Q05949-1", "kinase_gene_name": "BUR2", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ], "site_lbl": "Ser1032" }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "PubMed", "id": "31462158", "url": "https://glygen.org/publication/PubMed/31462158" }, { "database": "SGD", "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser1032" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "mutagenesis_flag", "phosphorylation_flag" ], "glycosylation": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P27692-1.1015.1015", "categories": [ "glycosylation_flag", "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P27692-1.1025.1025", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P27692-1.1043.1043", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P27692-1.1052.1052", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.1043.1043", "start_pos": 1043, "end_pos": 1043, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "The transcription factor Spt4-Spt5 complex regulates the expression of ATG8 and ATG41.", "journal": "Autophagy", "date": "2020-07", "authors": "Wen Xin, Gatica Dami\u00e1n, Yin Zhangyuan, Hu Zehan, Dengjel J\u00f6rn, Klionsky Daniel J", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "reference": [ { "type": "PubMed", "id": "31462158", "url": "https://glygen.org/publication/PubMed/31462158" } ] }, { "title": "Phosphorylation of the transcription elongation factor Spt5 by yeast Bur1 kinase stimulates recruitment of the PAF complex.", "journal": "Molecular and cellular biology", "date": "2009-09", "authors": "Liu Ying, Warfield Linda, Zhang Chao, Luo Jie, Allen Jasmina, Lang Walter H, Ranish Jeffrey, Shokat Kevan M, Hahn Steven", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" } ] }, { "title": "Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.", "journal": "Genes & development", "date": "2009-08-15", "authors": "Huber Alexandre, Bodenmiller Bernd, Uotila Aino, Stahl Michael, Wanka Stefanie, Gerrits Bertran, Aebersold Ruedi, Loewith Robbie", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "31462158", "url": "https://glygen.org/publication/PubMed/31462158", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NKSTRDGGASAWGNQDDGNR", "down_seq": "AWNNQGNKSNYGGNSTWGGH", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Reduces autophagic activity; when associated with A-1009; A-1015; A-1015; A-1032; A-1052 and A-1058.", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "PubMed", "id": "31462158", "url": "https://glygen.org/publication/PubMed/31462158" } ] }, { "sequence_org": "S", "sequence_mut": "E", "comment": "Phosphomimetic mutation that exhibits up-regulated autophagy activity; when associated with E-1009; E-1015; E-1015; E-1032; E-1052 and E-1058.", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "PubMed", "id": "31462158", "url": "https://glygen.org/publication/PubMed/31462158" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P23293-1", "kinase_gene_name": "SGV1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ], "site_lbl": "Ser1043" }, { "kinase_uniprot_canonical_ac": "Q05949-1", "kinase_gene_name": "BUR2", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ], "site_lbl": "Ser1043" }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "PubMed", "id": "31462158", "url": "https://glygen.org/publication/PubMed/31462158" }, { "database": "SGD", "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser1043" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "mutagenesis_flag", "phosphorylation_flag" ], "glycosylation": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P27692-1.1025.1025", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P27692-1.1032.1032", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P27692-1.1052.1052", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P27692-1.1054.1054", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P27692-1.1058.1058", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P27692-1.1059.1059", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.1052.1052", "start_pos": 1052, "end_pos": 1052, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "The transcription factor Spt4-Spt5 complex regulates the expression of ATG8 and ATG41.", "journal": "Autophagy", "date": "2020-07", "authors": "Wen Xin, Gatica Dami\u00e1n, Yin Zhangyuan, Hu Zehan, Dengjel J\u00f6rn, Klionsky Daniel J", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "reference": [ { "type": "PubMed", "id": "31462158", "url": "https://glygen.org/publication/PubMed/31462158" } ] }, { "title": "Phosphorylation of the transcription elongation factor Spt5 by yeast Bur1 kinase stimulates recruitment of the PAF complex.", "journal": "Molecular and cellular biology", "date": "2009-09", "authors": "Liu Ying, Warfield Linda, Zhang Chao, Luo Jie, Allen Jasmina, Lang Walter H, Ranish Jeffrey, Shokat Kevan M, Hahn Steven", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "31462158", "url": "https://glygen.org/publication/PubMed/31462158", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SAWGNQDDGNRSAWNNQGNK", "down_seq": "NYGGNSTWGGH", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Reduces autophagic activity; when associated with A-1009; A-1015; A-1025; A-1032; A-1043, and A-1058.", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "PubMed", "id": "31462158", "url": "https://glygen.org/publication/PubMed/31462158" } ] }, { "sequence_org": "S", "sequence_mut": "E", "comment": "Phosphomimetic mutation that exhibits up-regulated autophagy activity; when associated with E-1009; E-1015; E-1025; E-1032; E-1043 and E-1058.", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "PubMed", "id": "31462158", "url": "https://glygen.org/publication/PubMed/31462158" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P23293-1", "kinase_gene_name": "SGV1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" } ], "site_lbl": "Ser1052" }, { "kinase_uniprot_canonical_ac": "Q05949-1", "kinase_gene_name": "BUR2", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" } ], "site_lbl": "Ser1052" }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "PubMed", "id": "31462158", "url": "https://glygen.org/publication/PubMed/31462158" }, { "database": "SGD", "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser1052" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "mutagenesis_flag", "phosphorylation_flag" ], "glycosylation": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P27692-1.1032.1032", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P27692-1.1043.1043", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P27692-1.1054.1054", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P27692-1.1058.1058", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P27692-1.1059.1059", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.1058.1058", "start_pos": 1058, "end_pos": 1058, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "The transcription factor Spt4-Spt5 complex regulates the expression of ATG8 and ATG41.", "journal": "Autophagy", "date": "2020-07", "authors": "Wen Xin, Gatica Dami\u00e1n, Yin Zhangyuan, Hu Zehan, Dengjel J\u00f6rn, Klionsky Daniel J", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "reference": [ { "type": "PubMed", "id": "31462158", "url": "https://glygen.org/publication/PubMed/31462158" } ] }, { "title": "Phosphorylation of the transcription elongation factor Spt5 by yeast Bur1 kinase stimulates recruitment of the PAF complex.", "journal": "Molecular and cellular biology", "date": "2009-09", "authors": "Liu Ying, Warfield Linda, Zhang Chao, Luo Jie, Allen Jasmina, Lang Walter H, Ranish Jeffrey, Shokat Kevan M, Hahn Steven", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" } ] }, { "title": "Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.", "journal": "Genes & development", "date": "2009-08-15", "authors": "Huber Alexandre, Bodenmiller Bernd, Uotila Aino, Stahl Michael, Wanka Stefanie, Gerrits Bertran, Aebersold Ruedi, Loewith Robbie", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "31462158", "url": "https://glygen.org/publication/PubMed/31462158", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DDGNRSAWNNQGNKSNYGGN", "down_seq": "TWGGH", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Reduces autophagic activity; when associated with A-1009; A-1015; A-1025; A-1032; A-1043, and A-1052.", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "PubMed", "id": "31462158", "url": "https://glygen.org/publication/PubMed/31462158" } ] }, { "sequence_org": "S", "sequence_mut": "E", "comment": "Phosphomimetic mutation that exhibits up-regulated autophagy activity; when associated with E-1009; E-1015; E-1025; E-1032; E-1043 and E-1052.", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "PubMed", "id": "31462158", "url": "https://glygen.org/publication/PubMed/31462158" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P23293-1", "kinase_gene_name": "SGV1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ], "site_lbl": "Ser1058" }, { "kinase_uniprot_canonical_ac": "Q05949-1", "kinase_gene_name": "BUR2", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ], "site_lbl": "Ser1058" }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "PubMed", "id": "31462158", "url": "https://glygen.org/publication/PubMed/31462158" }, { "database": "SGD", "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser1058" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "mutagenesis_flag", "phosphorylation_flag" ], "glycosylation": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P27692-1.1043.1043", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P27692-1.1052.1052", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P27692-1.1054.1054", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P27692-1.1059.1059", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.1000.1000", "start_pos": 1000, "end_pos": 1000, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphorylation of the transcription elongation factor Spt5 by yeast Bur1 kinase stimulates recruitment of the PAF complex.", "journal": "Molecular and cellular biology", "date": "2009-09", "authors": "Liu Ying, Warfield Linda, Zhang Chao, Luo Jie, Allen Jasmina, Lang Walter H, Ranish Jeffrey, Shokat Kevan M, Hahn Steven", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" } ] } ], "crossref": [ { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KSSWGGASTWASGGESNGAM", "down_seq": "TWGGTGDRSAYGGASTWGGN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P23293-1", "kinase_gene_name": "SGV1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" } ], "site_lbl": "Ser1000" }, { "kinase_uniprot_canonical_ac": "Q05949-1", "kinase_gene_name": "BUR2", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" } ], "site_lbl": "Ser1000" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P27692-1.981.981", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P27692-1.987.987", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P27692-1.1009.1009", "categories": [ "glycosylation_flag", "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P27692-1.1015.1015", "categories": [ "glycosylation_flag", "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.1054.1054", "start_pos": 1054, "end_pos": 1054, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "WGNQDDGNRSAWNNQGNKSN", "down_seq": "GGNSTWGGH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Tyr1054" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P27692-1.1043.1043", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P27692-1.1052.1052", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P27692-1.1058.1058", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P27692-1.1059.1059", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.1059.1059", "start_pos": 1059, "end_pos": 1059, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "DGNRSAWNNQGNKSNYGGNS", "down_seq": "WGGH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr1059" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P27692-1.1043.1043", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P27692-1.1052.1052", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P27692-1.1054.1054", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P27692-1.1058.1058", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.122.122", "start_pos": 122, "end_pos": 122, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QATLNTDSSEANEIVKKEEG", "down_seq": "DERKRPREEDTKNSDGDTKD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser122" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "upstream", "id": "P27692-1.133.133", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P27692-1.136.136", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.133.133", "start_pos": 133, "end_pos": 133, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-02-13", "authors": "Chi An, Huttenhower Curtis, Geer Lewis Y, Coon Joshua J, Syka John E P, Bai Dina L, Shabanowitz Jeffrey, Burke Daniel J, Troyanskaya Olga G, Hunt Donald F", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] } ], "crossref": [ { "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "NEIVKKEEGSDERKRPREED", "down_seq": "KNSDGDTKDEGDNKDEDDDE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "site_lbl": "Thr133" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P27692-1.122.122", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P27692-1.136.136", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.136.136", "start_pos": 136, "end_pos": 136, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-02-13", "authors": "Chi An, Huttenhower Curtis, Geer Lewis Y, Coon Joshua J, Syka John E P, Bai Dina L, Shabanowitz Jeffrey, Burke Daniel J, Troyanskaya Olga G, Hunt Donald F", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VKKEEGSDERKRPREEDTKN", "down_seq": "DGDTKDEGDNKDEDDDEDDD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "PubMed", "id": "17287358", "url": "https://glygen.org/publication/PubMed/17287358" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "SGD", "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser136" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "P27692-1.122.122", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P27692-1.133.133", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.188.188", "start_pos": 188, "end_pos": 188, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "APTKRRRQERNRFLDIEAEV", "down_seq": "DDEDEDEDEEDSELVREGFI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "SGD", "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser188" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.209.209", "start_pos": 209, "end_pos": 209, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "DDEDEDEDEEDSELVREGFI", "down_seq": "HGDDEDDEASAPGARRDDRL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr209" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "upstream", "id": "P27692-1.219.219", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.219.219", "start_pos": 219, "end_pos": 219, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DSELVREGFITHGDDEDDEA", "down_seq": "APGARRDDRLHRQLDQDLNK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "SGD", "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser219" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "P27692-1.209.209", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.240.240", "start_pos": 240, "end_pos": 240, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "APGARRDDRLHRQLDQDLNK", "down_seq": "SEEDAQRLAKELRERYGRSS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr240" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "P27692-1.241.241", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.2.2", "start_pos": 2, "end_pos": 2, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "The spt5 C-terminal region recruits yeast 3' RNA cleavage factor I.", "journal": "Molecular and cellular biology", "date": "2012-04", "authors": "Mayer Andreas, Schreieck Amelie, Lidschreiber Michael, Leike Kristin, Martin Dietmar E, Cramer Patrick", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "22290438", "url": "https://glygen.org/publication/PubMed/22290438" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "22290438", "url": "https://glygen.org/publication/PubMed/22290438", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "M", "down_seq": "DNSDTNVSMQDHDQQFADPV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "22290438", "url": "https://glygen.org/publication/PubMed/22290438" }, { "database": "SGD", "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser2" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P27692-1.0.0", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P27692-1.5.5", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P27692-1.7.7", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.343.343", "start_pos": 343, "end_pos": 343, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LSIFQRDNYTGRIYIEAPKQ", "down_seq": "VIEKFCNGVPDIYISQKLLI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser343" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "upstream", "id": "P27692-1.358.358", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.358.358", "start_pos": 358, "end_pos": 358, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Mol. Cell. Proteomics", "date": "2008", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EAPKQSVIEKFCNGVPDIYI", "down_seq": "QKLLIPVQELPLLLKPNKSD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser358" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P27692-1.343.343", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.35.35", "start_pos": 35, "end_pos": 35, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007-06-19", "authors": "Smolka Marcus B, Albuquerque Claudio P, Chen Sheng-hong, Zhou Huilin", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Mol. Cell. Proteomics", "date": "2008", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] } ], "crossref": [ { "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470", "database": "SGD", "categories": [ "Organism-specific" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "DQQFADPVVVPQSTDTKDEN", "down_seq": "SDKDTVDSGNVTTTESTERA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "17563356", "url": "https://glygen.org/publication/PubMed/17563356" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470" } ], "site_lbl": "Thr35" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "P27692-1.36.36", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P27692-1.40.40", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P27692-1.43.43", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P27692-1.47.47", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P27692-1.48.48", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.36.36", "start_pos": 36, "end_pos": 36, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A global protein kinase and phosphatase interaction network in yeast.", "journal": "Science (New York, N.Y.)", "date": "2010-05-21", "authors": "Breitkreutz Ashton, Choi Hyungwon, Sharom Jeffrey R, Boucher Lorrie, Neduva Victor, Larsen Brett, Lin Zhen-Yuan, Breitkreutz Bobby-Joe, Stark Chris, Liu Guomin, Ahn Jessica, Dewar-Darch Danielle, Reguly Teresa, Tang Xiaojing, Almeida Ricardo, Qin Zhaohui Steve, Pawson Tony, Gingras Anne-Claude, Nesvizhskii Alexey I, Tyers Mike", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" } ] }, { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Mol. Cell. Proteomics", "date": "2008", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Glucose intake hampers PKA-regulated HSP90 chaperone activity.", "journal": "eLife", "date": "2018-12-05", "authors": "Chen Yu-Chen, Jiang Pei-Heng, Chen Hsuan-Ming, Chen Chang-Han, Wang Yi-Ting, Chen Yu-Ju, Yu Chia-Jung, Teng Shu-Chun", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QQFADPVVVPQSTDTKDENT", "down_seq": "DKDTVDSGNVTTTESTERAE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "20489023", "url": "https://glygen.org/publication/PubMed/20489023" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "30516470", "url": "https://glygen.org/publication/PubMed/30516470" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser36" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "P27692-1.35.35", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P27692-1.40.40", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P27692-1.43.43", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P27692-1.47.47", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P27692-1.48.48", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 7 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.40.40", "start_pos": 40, "end_pos": 40, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.", "journal": "Molecular biology of the cell", "date": "2010-10-01", "authors": "Soulard Alexandre, Cremonesi Alessio, Moes Suzette, Sch\u00fctz Fr\u00e9d\u00e9ric, Jen\u00f6 Paul, Hall Michael N", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "DPVVVPQSTDTKDENTSDKD", "down_seq": "VDSGNVTTTESTERAESTSN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "20702584", "url": "https://glygen.org/publication/PubMed/20702584" }, { "database": "SGD", "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr40" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "P27692-1.35.35", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P27692-1.36.36", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P27692-1.43.43", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P27692-1.47.47", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P27692-1.48.48", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P27692-1.57.57", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.43.43", "start_pos": 43, "end_pos": 43, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VVPQSTDTKDENTSDKDTVD", "down_seq": "GNVTTTESTERAESTSNIPP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser43" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "P27692-1.35.35", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P27692-1.36.36", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P27692-1.40.40", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P27692-1.47.47", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P27692-1.48.48", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P27692-1.57.57", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.47.47", "start_pos": 47, "end_pos": 47, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "STDTKDENTSDKDTVDSGNV", "down_seq": "TTESTERAESTSNIPPLDGE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr47" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P27692-1.35.35", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P27692-1.36.36", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P27692-1.40.40", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P27692-1.43.43", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P27692-1.48.48", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P27692-1.57.57", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.48.48", "start_pos": 48, "end_pos": 48, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "TDTKDENTSDKDTVDSGNVT", "down_seq": "TESTERAESTSNIPPLDGEE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr48" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P27692-1.35.35", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P27692-1.36.36", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P27692-1.40.40", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P27692-1.43.43", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P27692-1.47.47", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P27692-1.57.57", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.523.523", "start_pos": 523, "end_pos": 523, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EELARFGSKEGAVDLTSVSQ", "down_seq": "IKKAQAAKVTFQPGDRIEVL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser523" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.57.57", "start_pos": 57, "end_pos": 57, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Mol. Cell. Proteomics", "date": "2008", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DKDTVDSGNVTTTESTERAE", "down_seq": "TSNIPPLDGEEKEAKSEPQQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser57" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P27692-1.40.40", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "P27692-1.43.43", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P27692-1.47.47", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P27692-1.48.48", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.5.5", "start_pos": 5, "end_pos": 5, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MSDN", "down_seq": "DTNVSMQDHDQQFADPVVVP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser5" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "P27692-1.0.0", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P27692-1.2.2", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P27692-1.7.7", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.793.793", "start_pos": 793, "end_pos": 793, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PEIISKMGPPSSKTFQQPIQ", "down_seq": "RGGREVALGKTVRIRSAGYK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser793" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "P27692-1.783.783", "categories": [ "glycosylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P27692-1.784.784", "categories": [ "glycosylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P27692-1.809.809", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.7.7", "start_pos": 7, "end_pos": 7, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Pol II CTD kinases Bur1 and Kin28 promote Spt5 CTR-independent recruitment of Paf1 complex.", "journal": "The EMBO journal", "date": "2012-08-15", "authors": "Qiu Hongfang, Hu Cuihua, Gaur Naseem A, Hinnebusch Alan G", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "22796944", "url": "https://glygen.org/publication/PubMed/22796944" } ] } ], "crossref": [ { "id": "P27692", "url": "https://www.ebi.ac.uk/intact/interactors/id:P27692*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "22796944", "url": "https://glygen.org/publication/PubMed/22796944", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "MSDNSD", "down_seq": "NVSMQDHDQQFADPVVVPQS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "IntAct", "id": "P27692", "url": "https://www.ebi.ac.uk/intact/interactors/id:P27692*" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "22796944", "url": "https://glygen.org/publication/PubMed/22796944" } ], "site_lbl": "Thr7" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P27692-1.0.0", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P27692-1.2.2", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P27692-1.5.5", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.809.809", "start_pos": 809, "end_pos": 809, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] } ], "crossref": [ { "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QPIQSRGGREVALGKTVRIR", "down_seq": "AGYKGQLGIVKDVNGDKATV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser809" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P27692-1.793.793", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.905.905", "start_pos": 905, "end_pos": 905, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] } ], "crossref": [ { "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "ATGGIAAGAAATSSGLSGGM", "down_seq": "PGWSSFDGGKTPAVNAHGGS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000004470", "url": "https://www.yeastgenome.org/locus/S000004470" }, { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr905" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.931.931", "start_pos": 931, "end_pos": 931, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphorylation of the transcription elongation factor Spt5 by yeast Bur1 kinase stimulates recruitment of the PAF complex.", "journal": "Molecular and cellular biology", "date": "2009-09", "authors": "Liu Ying, Warfield Linda, Zhang Chao, Luo Jie, Allen Jasmina, Lang Walter H, Ranish Jeffrey, Shokat Kevan M, Hahn Steven", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" } ] } ], "crossref": [ { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FDGGKTPAVNAHGGSGGGGV", "down_seq": "SWGGASTWGGQGNGGASAWG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P23293-1", "kinase_gene_name": "SGV1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" } ], "site_lbl": "Ser931" }, { "kinase_uniprot_canonical_ac": "Q05949-1", "kinase_gene_name": "BUR2", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" } ], "site_lbl": "Ser931" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "upstream", "id": "P27692-1.937.937", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P27692-1.948.948", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.937.937", "start_pos": 937, "end_pos": 937, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphorylation of the transcription elongation factor Spt5 by yeast Bur1 kinase stimulates recruitment of the PAF complex.", "journal": "Molecular and cellular biology", "date": "2009-09", "authors": "Liu Ying, Warfield Linda, Zhang Chao, Luo Jie, Allen Jasmina, Lang Walter H, Ranish Jeffrey, Shokat Kevan M, Hahn Steven", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" } ] } ], "crossref": [ { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PAVNAHGGSGGGGVSSWGGA", "down_seq": "TWGGQGNGGASAWGGAGGGA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P23293-1", "kinase_gene_name": "SGV1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" } ], "site_lbl": "Ser937" }, { "kinase_uniprot_canonical_ac": "Q05949-1", "kinase_gene_name": "BUR2", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" } ], "site_lbl": "Ser937" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "P27692-1.931.931", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P27692-1.948.948", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.948.948", "start_pos": 948, "end_pos": 948, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphorylation of the transcription elongation factor Spt5 by yeast Bur1 kinase stimulates recruitment of the PAF complex.", "journal": "Molecular and cellular biology", "date": "2009-09", "authors": "Liu Ying, Warfield Linda, Zhang Chao, Luo Jie, Allen Jasmina, Lang Walter H, Ranish Jeffrey, Shokat Kevan M, Hahn Steven", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" } ] } ], "crossref": [ { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GGVSSWGGASTWGGQGNGGA", "down_seq": "AWGGAGGGASAWGGQGTGAT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P23293-1", "kinase_gene_name": "SGV1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" } ], "site_lbl": "Ser948" }, { "kinase_uniprot_canonical_ac": "Q05949-1", "kinase_gene_name": "BUR2", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" } ], "site_lbl": "Ser948" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P27692-1.931.931", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P27692-1.937.937", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P27692-1.958.958", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.958.958", "start_pos": 958, "end_pos": 958, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphorylation of the transcription elongation factor Spt5 by yeast Bur1 kinase stimulates recruitment of the PAF complex.", "journal": "Molecular and cellular biology", "date": "2009-09", "authors": "Liu Ying, Warfield Linda, Zhang Chao, Luo Jie, Allen Jasmina, Lang Walter H, Ranish Jeffrey, Shokat Kevan M, Hahn Steven", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" } ] } ], "crossref": [ { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TWGGQGNGGASAWGGAGGGA", "down_seq": "AWGGQGTGATSTWGGASAWG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P23293-1", "kinase_gene_name": "SGV1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" } ], "site_lbl": "Ser958" }, { "kinase_uniprot_canonical_ac": "Q05949-1", "kinase_gene_name": "BUR2", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" } ], "site_lbl": "Ser958" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "P27692-1.948.948", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P27692-1.969.969", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P27692-1.975.975", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.969.969", "start_pos": 969, "end_pos": 969, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphorylation of the transcription elongation factor Spt5 by yeast Bur1 kinase stimulates recruitment of the PAF complex.", "journal": "Molecular and cellular biology", "date": "2009-09", "authors": "Liu Ying, Warfield Linda, Zhang Chao, Luo Jie, Allen Jasmina, Lang Walter H, Ranish Jeffrey, Shokat Kevan M, Hahn Steven", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" } ] } ], "crossref": [ { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AWGGAGGGASAWGGQGTGAT", "down_seq": "TWGGASAWGNKSSWGGASTW", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P23293-1", "kinase_gene_name": "SGV1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" } ], "site_lbl": "Ser969" }, { "kinase_uniprot_canonical_ac": "Q05949-1", "kinase_gene_name": "BUR2", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" } ], "site_lbl": "Ser969" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P27692-1.958.958", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P27692-1.975.975", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P27692-1.981.981", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P27692-1.987.987", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.975.975", "start_pos": 975, "end_pos": 975, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphorylation of the transcription elongation factor Spt5 by yeast Bur1 kinase stimulates recruitment of the PAF complex.", "journal": "Molecular and cellular biology", "date": "2009-09", "authors": "Liu Ying, Warfield Linda, Zhang Chao, Luo Jie, Allen Jasmina, Lang Walter H, Ranish Jeffrey, Shokat Kevan M, Hahn Steven", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" } ] } ], "crossref": [ { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GGASAWGGQGTGATSTWGGA", "down_seq": "AWGNKSSWGGASTWASGGES", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P23293-1", "kinase_gene_name": "SGV1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" } ], "site_lbl": "Ser975" }, { "kinase_uniprot_canonical_ac": "Q05949-1", "kinase_gene_name": "BUR2", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" } ], "site_lbl": "Ser975" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P27692-1.958.958", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P27692-1.969.969", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P27692-1.981.981", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P27692-1.987.987", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.981.981", "start_pos": 981, "end_pos": 981, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphorylation of the transcription elongation factor Spt5 by yeast Bur1 kinase stimulates recruitment of the PAF complex.", "journal": "Molecular and cellular biology", "date": "2009-09", "authors": "Liu Ying, Warfield Linda, Zhang Chao, Luo Jie, Allen Jasmina, Lang Walter H, Ranish Jeffrey, Shokat Kevan M, Hahn Steven", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" } ] } ], "crossref": [ { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GGQGTGATSTWGGASAWGNK", "down_seq": "SWGGASTWASGGESNGAMST", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P23293-1", "kinase_gene_name": "SGV1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" } ], "site_lbl": "Ser981" }, { "kinase_uniprot_canonical_ac": "Q05949-1", "kinase_gene_name": "BUR2", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" } ], "site_lbl": "Ser981" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P27692-1.969.969", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P27692-1.975.975", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P27692-1.987.987", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P27692-1.1000.1000", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P27692-1.987.987", "start_pos": 987, "end_pos": 987, "uniprot_canonical_ac": "P27692-1", "length": 1063, "uniprot_id": "SPT5_YEAST", "protein_name": "Transcription elongation factor SPT5", "refseq_ac": "NP_013703", "refseq_name": "transcription elongation factor SPT5", "gene_name": "SPT5", "gene_names_uniprotkb": "SPT5; YM9571.08", "gene_names_refseq": "SPT5", "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P27692", "url": "https://www.uniprot.org/uniprotkb/P27692" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "publication": [ { "title": "Phosphorylation of the transcription elongation factor Spt5 by yeast Bur1 kinase stimulates recruitment of the PAF complex.", "journal": "Molecular and cellular biology", "date": "2009-09", "authors": "Liu Ying, Warfield Linda, Zhang Chao, Luo Jie, Allen Jasmina, Lang Walter H, Ranish Jeffrey, Shokat Kevan M, Hahn Steven", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" } ], "reference": [ { "type": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" } ] } ], "crossref": [ { "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ATSTWGGASAWGNKSSWGGA", "down_seq": "TWASGGESNGAMSTWGGTGD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P23293-1", "kinase_gene_name": "SGV1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" } ], "site_lbl": "Ser987" }, { "kinase_uniprot_canonical_ac": "Q05949-1", "kinase_gene_name": "BUR2", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P27692", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P27692" }, { "database": "PubMed", "id": "19581288", "url": "https://glygen.org/publication/PubMed/19581288" } ], "site_lbl": "Ser987" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "501", "end_pos": "501" }, { "start_pos": "783", "end_pos": "783" }, { "start_pos": "784", "end_pos": "784" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1058", "end_pos": "1058" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1000", "end_pos": "1000" }, { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1025", "end_pos": "1025" }, { "start_pos": "1032", "end_pos": "1032" }, { "start_pos": "1043", "end_pos": "1043" }, { "start_pos": "1052", "end_pos": "1052" }, { "start_pos": "1054", "end_pos": "1054" }, { "start_pos": "1058", "end_pos": "1058" }, { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "133", "end_pos": "133" }, { "start_pos": "136", "end_pos": "136" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "240", "end_pos": "240" }, { "start_pos": "241", "end_pos": "241" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "358", "end_pos": "358" }, { "start_pos": "35", "end_pos": "35" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "47", "end_pos": "47" }, { "start_pos": "48", "end_pos": "48" }, { "start_pos": "523", "end_pos": "523" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "5", "end_pos": "5" }, { "start_pos": "793", "end_pos": "793" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "809", "end_pos": "809" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "931", "end_pos": "931" }, { "start_pos": "937", "end_pos": "937" }, { "start_pos": "948", "end_pos": "948" }, { "start_pos": "958", "end_pos": "958" }, { "start_pos": "969", "end_pos": "969" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "981", "end_pos": "981" }, { "start_pos": "987", "end_pos": "987" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P27692-1.969.969", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P27692-1.975.975", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P27692-1.981.981", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P27692-1.1000.1000", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] } ]