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"http://research.bioinformatics.udel.edu/iptmnet/entry/P42227" } ], "reference": [ { "type": "PubMed", "id": "15328362", "url": "https://glygen.org/publication/PubMed/15328362" } ] }, { "title": "A role of STAT3 in Rho GTPase-regulated cell migration and proliferation.", "journal": "The Journal of biological chemistry", "date": "2005", "authors": "Debidda M, Wang L, Zang H, Poli V, Zheng Y", "evidence": [ { "database": "iPTMnet", "id": "P42227", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42227" } ], "reference": [ { "type": "PubMed", "id": "15705584", "url": "https://glygen.org/publication/PubMed/15705584" } ] }, { "title": "Reduced STAT3 activity in mice mimics clinical disease syndromes.", "journal": "Biochemical and biophysical research communications", "date": "2005", "authors": "Shen Y, La Perle KM, Levy DE, Darnell JE Jr", "evidence": [ { "database": "iPTMnet", "id": "P42227", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42227" } ], "reference": [ { "type": "PubMed", "id": "15781265", "url": "https://glygen.org/publication/PubMed/15781265" } ] }, { "title": "Ultraviolet B exposure activates Stat3 signaling via phosphorylation at tyrosine705 in skin of SKH1 hairless mouse: a target for the management of skin cancer?", "journal": "Biochemical and biophysical research communications", "date": "2005", "authors": "Ahsan H, Aziz MH, Ahmad N", "evidence": [ { "database": "iPTMnet", "id": "P42227", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42227" } ], "reference": [ { "type": "PubMed", "id": "15936723", "url": "https://glygen.org/publication/PubMed/15936723" } ] }, { "title": "Differential effects of Stat3 inhibition in sparse vs confluent normal and breast cancer cells.", "journal": "Cancer letters", "date": "2006", "authors": "Anagnostopoulou A, Vultur A, Arulanandam R, Cao J, Turkson J, Jove R, Kim JS, Glenn M, Hamilton AD, Raptis L", "evidence": [ { "database": "iPTMnet", "id": "P42227", "url": 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"iPTMnet", "id": "P42227", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42227" } ], "reference": [ { "type": "PubMed", "id": "17283176", "url": "https://glygen.org/publication/PubMed/17283176" } ] }, { "title": "Sulindac induces apoptosis and inhibits tumor growth in vivo in head and neck squamous cell carcinoma.", "journal": "Neoplasia (New York, N.Y.)", "date": "2007", "authors": "Scheper MA, Nikitakis NG, Chaisuparat R, Montaner S, Sauk JJ", "evidence": [ { "database": "iPTMnet", "id": "P42227", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42227" } ], "reference": [ { "type": "PubMed", "id": "17401459", "url": "https://glygen.org/publication/PubMed/17401459" } ] }, { "title": "Therapeutic effects of STAT3 decoy oligodeoxynucleotide on human lung cancer in xenograft mice.", "journal": "BMC cancer", "date": "2007", "authors": "Zhang X, Zhang J, Wang L, Wei H, Tian Z", "evidence": [ { "database": "iPTMnet", "id": "P42227", "url": 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Kaluarachchi KK, Chen X, Bast RC Jr, Liao WS, McMurray JS", "evidence": [ { "database": "iPTMnet", "id": "P42227", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42227" } ], "reference": [ { "type": "PubMed", "id": "21486047", "url": "https://glygen.org/publication/PubMed/21486047" } ] }, { "title": "B7-H3 silencing increases paclitaxel sensitivity by abrogating Jak2/Stat3 phosphorylation.", "journal": "Molecular cancer therapeutics", "date": "2011", "authors": "Liu H, Tekle C, Chen YW, Kristian A, Zhao Y, Zhou M, Liu Z, Ding Y, Wang B, Maelandsmo GM, Nesland JM, Fodstad O, Tan M", "evidence": [ { "database": "iPTMnet", "id": "P42227", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42227" } ], "reference": [ { "type": "PubMed", "id": "21518725", "url": "https://glygen.org/publication/PubMed/21518725" } ] }, { "title": "Activation of peroxisome proliferator-activated receptor-beta/-delta (PPAR-beta/-delta) ameliorates insulin signaling and reduces SOCS3 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Pohlmann C", "evidence": [ { "database": "iPTMnet", "id": "P42227", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42227" } ], "reference": [ { "type": "PubMed", "id": "24093616", "url": "https://glygen.org/publication/PubMed/24093616" } ] }, { "title": "Suppression of HIF-1alpha by Valproic Acid Sustains Self-Renewal of Mouse Embryonic Stem Cells under Hypoxia In Vitro.", "journal": "Biomolecules & therapeutics", "date": "2012", "authors": "Lee HJ, Kim KW", "evidence": [ { "database": "iPTMnet", "id": "P42227", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42227" } ], "reference": [ { "type": "PubMed", "id": "24130924", "url": "https://glygen.org/publication/PubMed/24130924" } ] }, { "title": "Development, characterization, and reversal of acquired resistance to the MEK1 inhibitor selumetinib (AZD6244) in an in vivo model of childhood astrocytoma.", "journal": "Clinical cancer research : an official journal of the American Association for Cancer 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Smith DR, Morrow D, Tessler L, Calcutt NA, Fernyhough P", "evidence": [ { "database": "iPTMnet", "id": "P42227", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42227" } ], "reference": [ { "type": "PubMed", "id": "24682898", "url": "https://glygen.org/publication/PubMed/24682898" } ] }, { "title": "Evidence for a prosurvival role of alpha-7 nicotinic acetylcholine receptor in alternatively (M2)-activated macrophages.", "journal": "Physiological reports", "date": "2013", "authors": "Lee RH, Vazquez G", "evidence": [ { "database": "iPTMnet", "id": "P42227", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42227" } ], "reference": [ { "type": "PubMed", "id": "24744866", "url": "https://glygen.org/publication/PubMed/24744866" } ] }, { "title": "Metformin inhibits the IL-6-induced epithelial-mesenchymal transition and lung adenocarcinoma growth and metastasis.", "journal": "PloS one", "date": "2014", "authors": "Zhao Z, Cheng X, Wang Y, Han R, Li L, Xiang T, He L, Long H, Zhu B, He Y", "evidence": [ { "database": "iPTMnet", "id": "P42227", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42227" } ], "reference": [ { "type": "PubMed", "id": "24789104", "url": "https://glygen.org/publication/PubMed/24789104" } ] }, { "title": "Assessing the role of STAT3 in DC differentiation and autologous DC immunotherapy in mouse models of GBM.", "journal": "PloS one", "date": "2014", "authors": "Assi H, Espinosa J, Suprise S, Sofroniew M, Doherty R, Zamler D, Lowenstein PR, Castro MG", "evidence": [ { "database": "iPTMnet", "id": "P42227", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42227" } ], "reference": [ { "type": "PubMed", "id": "24806510", "url": "https://glygen.org/publication/PubMed/24806510" } ] }, { "title": "Biologically active leptin-related synthetic peptides activate STAT3 via phosphorylation of ERK1/2 and PI-3K.", "journal": "Peptides", "date": "2014", "authors": "Lin HY, Yang SH, Tang HY, Cheng GY, Davis PJ, 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}, { "title": "YAP1 and TAZ Control Pancreatic Cancer Initiation in Mice by Direct Up-regulation of JAK-STAT3 Signaling.", "journal": "Gastroenterology", "date": "2016", "authors": "Gruber R, Panayiotou R, Nye E, Spencer-Dene B, Stamp G, Behrens A", "evidence": [ { "database": "iPTMnet", "id": "P42227", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42227" } ], "reference": [ { "type": "PubMed", "id": "27215660", "url": "https://glygen.org/publication/PubMed/27215660" } ] }, { "title": "IL-6/STAT3 signaling in mice with dysfunctional type-2 ryanodine receptor.", "journal": "JAK-STAT", "date": "2015", "authors": "Huang TQ, Willis MS, Meissner G", "evidence": [ { "database": "iPTMnet", "id": "P42227", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42227" } ], "reference": [ { "type": "PubMed", "id": "27217982", "url": "https://glygen.org/publication/PubMed/27217982" } ] }, { "title": "Suspension survival mediated by PP2A-STAT3-Col XVII determines tumour 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"2018", "authors": "Cuvelier E, Mequinion M, Leghay C, Sibran W, Stievenard A, Sarchione A, Bonte MA, Vanbesien-Mailliot C, Viltart O, Saitoski K, Caron E, Labarthe A, Comptdaer T, Semaille P, Carrie H, Mutez E, Gressier B, Destee A, Chartier-Harlin MC, Belarbi K", "evidence": [ { "database": "iPTMnet", "id": "P42227", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42227" } ], "reference": [ { "type": "PubMed", "id": "30333721", "url": "https://glygen.org/publication/PubMed/30333721" } ] }, { "title": "Loss of Stat6 affects chromatin condensation in intestinal epithelial cells causing diverse outcome in murine models of inflammation-associated and sporadic colon carcinogenesis.", "journal": "Oncogene", "date": "2019", "authors": "De Oliveira T, Ramakrishnan M, Diamanti MA, Ziegler PK, Brombacher F, Greten FR", "evidence": [ { "database": "iPTMnet", "id": "P42227", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42227" } ], "reference": [ { "type": 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"date": "2011", "authors": "Hannigan A, Qureshi AM, Nixon C, Tsimbouri PM, Jones S, Philbey AW, Wilson JB", "evidence": [ { "database": "iPTMnet", "id": "P42227", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42227" } ], "reference": [ { "type": "PubMed", "id": "21291541", "url": "https://glygen.org/publication/PubMed/21291541" } ] }, { "title": "Ultraviolet radiation and 12-O-tetradecanoylphorbol-13-acetate-induced interaction of mouse epidermal protein kinase Cepsilon with Stat3 involve integration with ERK1/2.", "journal": "Molecular carcinogenesis", "date": "2012", "authors": "Sand JM, Bin Hafeez B, Aziz MH, Siebers EM, Dreckschmidt NE, Verma AK", "evidence": [ { "database": "iPTMnet", "id": "P42227", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42227" } ], "reference": [ { "type": "PubMed", "id": "21480396", "url": "https://glygen.org/publication/PubMed/21480396" } ] }, { "title": "Activation of peroxisome proliferator-activated receptor-beta/-delta (PPAR-beta/-delta) ameliorates insulin signaling and reduces SOCS3 levels by inhibiting STAT3 in interleukin-6-stimulated adipocytes.", "journal": "Diabetes", "date": "2011", "authors": "Serrano-Marco L, Rodriguez-Calvo R, El Kochairi I, Palomer X, Michalik L, Wahli W, Vazquez-Carrera M", "evidence": [ { "database": "iPTMnet", "id": "P42227", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42227" } ], "reference": [ { "type": "PubMed", "id": "21617181", "url": "https://glygen.org/publication/PubMed/21617181" } ] }, { "title": "FGF2 regulates melanocytes viability through the STAT3-transactivated PAX3 transcription.", "journal": "Cell death and differentiation", "date": "2012", "authors": "Dong L, Li Y, Cao J, Liu F, Pier E, Chen J, Xu Z, Chen C, Wang RA, Cui R", "evidence": [ { "database": "iPTMnet", "id": "P42227", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42227" } ], "reference": [ { "type": "PubMed", "id": "21997191", "url": 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"date": "2016", "authors": "Zhao L, Du X, Huang K, Zhang T, Teng Z, Niu W, Wang C, Xia G", "evidence": [ { "database": "iPTMnet", "id": "P42227", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42227" } ], "reference": [ { "type": "PubMed", "id": "27050391", "url": "https://glygen.org/publication/PubMed/27050391" } ] }, { "title": "Tissue-specific conditional PKCepsilon knockout mice: a model to precisely reveal PKCepsilon functional role in initiation, promotion and progression of cancer.", "journal": "Oncotarget", "date": "2016", "authors": "Hafeez BB, Meske L, Singh A, Singh A, Zhong W, Powers P, John M, Griep AE, Verma AK", "evidence": [ { "database": "iPTMnet", "id": "P42227", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42227" } ], "reference": [ { "type": "PubMed", "id": "27102301", "url": "https://glygen.org/publication/PubMed/27102301" } ] }, { "title": "Suspension survival mediated by PP2A-STAT3-Col XVII determines tumour initiation and 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Molecular basis of disease", "date": "2017-10", "authors": "DeMartini Theodore, Nowell Marchele, James Jeanne, Williamson Lauren, Lahni Patrick, Shen Hui, Kaplan Jennifer M", "evidence": [ { "database": "iPTMnet", "id": "P42227", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42227" } ], "reference": [ { "type": "PubMed", "id": "28625915", "url": "https://glygen.org/publication/PubMed/28625915" } ] }, { "title": "Inactivation of STAT3 Signaling Impairs Hair Cell Differentiation in the Developing Mouse Cochlea.", "journal": "Stem cell reports", "date": "2017", "authors": "Chen Q, Quan Y, Wang N, Xie C, Ji Z, He H, Chai R, Li H, Yin S, Chin YE, Wei X, Gao WQ", "evidence": [ { "database": "iPTMnet", "id": "P42227", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42227" } ], "reference": [ { "type": "PubMed", "id": "28669599", "url": "https://glygen.org/publication/PubMed/28669599" } ] }, { "title": "Phospho-valproic acid inhibits pancreatic cancer growth in 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